{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T20:00:08Z","timestamp":1779307208646,"version":"3.51.4"},"reference-count":33,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2008,5,1]],"date-time":"2008-05-01T00:00:00Z","timestamp":1209600000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,5,1]],"date-time":"2008-05-01T00:00:00Z","timestamp":1209600000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Placenta"],"published-print":{"date-parts":[[2008,5]]},"DOI":"10.1016\/j.placenta.2008.01.001","type":"journal-article","created":{"date-parts":[[2008,3,19]],"date-time":"2008-03-19T01:40:43Z","timestamp":1205890843000},"page":"454-460","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":38,"title":["Placental Mesenchymal Dysplasia with Beckwith\u2013Wiedemann Syndrome Fetus in the Context of Biparental and Androgenic Cell Lines"],"prefix":"10.1016","volume":"29","author":[{"given":"D.","family":"H'mida","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Gribaa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Yacoubi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Chaieb","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Adala","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Elghezal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Saad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.placenta.2008.01.001_bib1","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/S0344-0338(11)80791-0","article-title":"Placental vascular anomaly with diffuse mesenchymal stem villous hyperplasia. A new clinico-pathological entity?","volume":"187","author":"Moscoso","year":"1991","journal-title":"Pathol Res Pract"},{"key":"10.1016\/j.placenta.2008.01.001_bib2","doi-asserted-by":"crossref","first-page":"621","DOI":"10.3109\/15513819309048250","article-title":"Angiomatous malformation of placental chorionic stem vessels and pseudo-partial molar placentas: report of five cases","volume":"13","author":"Sander","year":"1993","journal-title":"Pediatr Pathol"},{"key":"10.1016\/j.placenta.2008.01.001_bib3","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/S0143-4004(97)90012-6","article-title":"Perinatal features associated with placental mesenchymal dysplasia","volume":"18","author":"Jauniaux","year":"1997","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2008.01.001_bib4","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1309\/RV45HRD53YQ2YFTP","article-title":"Placental mesenchymal dysplasia is associated with high rates of intrauterine growth restriction and fetal demise: a report of 11 new cases and a review of the literature","volume":"126","author":"Pham","year":"2006","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.placenta.2008.01.001_bib5","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1038\/268633a0","article-title":"Androgenetic origin of hydatidiform mole","volume":"268","author":"Kajii","year":"1977","journal-title":"Nature"},{"key":"10.1016\/j.placenta.2008.01.001_bib6","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1038\/292551a0","article-title":"Dispermic origin of XY hydatidiform moles","volume":"292","author":"Ohama","year":"1981","journal-title":"Nature"},{"key":"10.1016\/j.placenta.2008.01.001_bib7","first-page":"1664","article-title":"Genetic studies of hydatidiform mole with 46,XY karyotype","volume":"33","author":"Ohama","year":"1981","journal-title":"Nippon Sanka Fujinka Gakkai Zasshi"},{"key":"10.1016\/j.placenta.2008.01.001_bib8","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/0002-9378(78)90829-3","article-title":"The syndromes of hydatidiform mole. I. Cytogenetic and morphologic correlations","volume":"131","author":"Szulman","year":"1978","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.placenta.2008.01.001_bib9","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/0090-8258(91)90080-O","article-title":"Application of gene amplification by polymerase chain reaction to genetic analysis of molar mitochondrial DNA: the detection of anuclear empty ovum as the cause of complete mole","volume":"40","author":"Azuma","year":"1991","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.placenta.2008.01.001_bib10","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1111\/j.1471-0528.1982.tb04693.x","article-title":"Complete and partial hydatidiform mole in Hawaii: cytogenetics, morphology and epidemiology","volume":"89","author":"Jacobs","year":"1982","journal-title":"Br J Obstet Gynaecol"},{"key":"10.1016\/j.placenta.2008.01.001_bib11","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1007\/BF00216452","article-title":"Parental origin of triploidy in human fetuses: evidence for genomic imprinting","volume":"92","author":"McFadden","year":"1993","journal-title":"Hum Genet"},{"key":"10.1016\/j.placenta.2008.01.001_bib12","first-page":"228","article-title":"Pathology of abortion: chromosomal and genetic correlations","author":"Kalousek","year":"1991","journal-title":"Monogr Pathol"},{"key":"10.1016\/j.placenta.2008.01.001_bib13","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1111\/j.1741-4520.2002.tb00897.x","article-title":"Suspected involvement of the X chromosome in placental mesenchymal dysplasia","volume":"42","author":"Arizawa","year":"2002","journal-title":"Congenit Anom Kyoto"},{"key":"10.1016\/j.placenta.2008.01.001_bib14","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1136\/jmg.2005.033571","article-title":"Androgenetic\/biparental mosaicism causes placental mesenchymal dysplasia","volume":"43","author":"Kaiser-Rogers","year":"2006","journal-title":"J Med Genet"},{"key":"10.1016\/j.placenta.2008.01.001_bib15","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1002\/pd.1103","article-title":"Placental mesenchymal dysplasia associated with fetal aneuploidy","volume":"25","author":"Cohen","year":"2005","journal-title":"Prenat Diagn"},{"key":"10.1016\/j.placenta.2008.01.001_bib16","first-page":"2638","article-title":"Sur une nouvelle technique d'analyse du caryotype humain","author":"Dutrillaux","year":"1971","journal-title":"C R Acad Sci Hebd Seances Acad Sci D"},{"key":"10.1016\/j.placenta.2008.01.001_bib17","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/0168-9525(91)90103-W","article-title":"Fluorescence in situ hybridization: applications in cytogenetics and gene mapping","volume":"7","author":"Trask","year":"1991","journal-title":"Trends Genet"},{"issue":"316","key":"10.1016\/j.placenta.2008.01.001_bib18","first-page":"318","article-title":"A nontoxic and versatile protein salting-out method for isolation of DNA","volume":"17","author":"Laitinen","year":"1994","journal-title":"Biotechniques"},{"key":"10.1016\/j.placenta.2008.01.001_bib19","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1046\/j.1365-2559.2001.01256.x","article-title":"Pseudo-partial moles: placental stem vessel hydrops and the association with Beckwith\u2013Wiedemann syndrome and complete moles","volume":"39","author":"Paradinas","year":"2001","journal-title":"Histopathology"},{"key":"10.1016\/j.placenta.2008.01.001_bib20","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1046\/j.0004-8666.2003.00130.x","article-title":"Placental mesenchymal dysplasia: a report of four cases with differentiation from partial hydatidiform mole","volume":"43","author":"Chan","year":"2003","journal-title":"Aust N Z J Obstet Gynaecol"},{"key":"10.1016\/j.placenta.2008.01.001_bib21","doi-asserted-by":"crossref","first-page":"e39","DOI":"10.1136\/jmg.2005.038398","article-title":"Molecular and genomic characterisation of cryptic chromosomal alterations leading to paternal duplication of the 11p15.5 Beckwith\u2013Wiedemann region","volume":"43","author":"Russo","year":"2006","journal-title":"J Med Genet"},{"key":"10.1016\/j.placenta.2008.01.001_bib22","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1002\/ajmg.10143","article-title":"Wiedemann\u2013Beckwith syndrome: further prenatal characterization of the condition","volume":"107","author":"Reish","year":"2002","journal-title":"Am J Med Genet"},{"key":"10.1016\/j.placenta.2008.01.001_bib23","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1086\/346031","article-title":"Association of in vitro fertilization with Beckwith\u2013Wiedemann syndrome and epigenetic alterations of LIT1 and H19","volume":"72","author":"DeBaun","year":"2003","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.placenta.2008.01.001_bib24","doi-asserted-by":"crossref","first-page":"3115","DOI":"10.1101\/gad.13.23.3115","article-title":"Oppositely imprinted genes p57(Kip2) and igf2 interact in a mouse model for Beckwith\u2013Wiedemann syndrome","volume":"13","author":"Caspary","year":"1999","journal-title":"Genes Dev"},{"key":"10.1016\/j.placenta.2008.01.001_bib25","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1136\/jmg.37.12.921","article-title":"Epigenotype\u2013phenotype correlations in Beckwith\u2013Wiedemann syndrome","volume":"37","author":"Engel","year":"2000","journal-title":"J Med Genet"},{"key":"10.1016\/j.placenta.2008.01.001_bib26","doi-asserted-by":"crossref","first-page":"2077","DOI":"10.1097\/01.ASN.0000023431.16173.55","article-title":"Renal abnormalities in Beckwith\u2013Wiedemann syndrome are associated with 11p15.5 uniparental disomy","volume":"13","author":"Goldman","year":"2002","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.placenta.2008.01.001_bib27","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1002\/ajmg.a.30595","article-title":"Factors associated with preterm delivery in mothers of children with Beckwith\u2013Wiedemann syndrome: a case cohort study from the BWS registry","volume":"134","author":"Wangler","year":"2005","journal-title":"Am J\u00a0Med Genet A"},{"key":"10.1016\/j.placenta.2008.01.001_bib28","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S1084-8592(99)80045-9","article-title":"Molecular genetic testing from paraffin-embedded tissue distinguishes nonmolar hydropic abortion from hydatidiform mole","volume":"4","author":"Bell","year":"1999","journal-title":"Mol Diagn"},{"key":"10.1016\/j.placenta.2008.01.001_bib29","first-page":"687","article-title":"Re: \u201cGestational trophoblastic diseases.\u201d Potential mechanism of formation of complete diploid moles","volume":"29","author":"Petignat","year":"2000","journal-title":"J Gynecol Obstet Biol Reprod (Paris)"},{"key":"10.1016\/j.placenta.2008.01.001_bib30","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1046\/j.1440-1827.2000.01100.x","article-title":"Mesenchymal dysplasia of the placenta","volume":"50","author":"Ohyama","year":"2000","journal-title":"Pathol Int"},{"key":"10.1016\/j.placenta.2008.01.001_bib31","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1093\/ajcp\/95.1.48","article-title":"An unusual venous anomaly of the placenta","volume":"95","author":"Lee","year":"1991","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.placenta.2008.01.001_bib32","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1002\/pd.1255","article-title":"Twin pregnancy with a chimeric androgenetic and biparental placenta in one twin displaying placental mesenchymal dysplasia phenotype","volume":"25","author":"Surti","year":"2005","journal-title":"Prenat Diagn"},{"key":"10.1016\/j.placenta.2008.01.001_bib33","doi-asserted-by":"crossref","first-page":"2459","DOI":"10.1093\/humrep\/17.9.2459","article-title":"Complete hydatidiform mole and normal live birth: a novel case of confined placental mosaicism: case report","volume":"17","author":"Makrydimas","year":"2002","journal-title":"Hum Reprod"}],"container-title":["Placenta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400408000155?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400408000155?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T17:38:29Z","timestamp":1758908309000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0143400408000155"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,5]]},"references-count":33,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2008,5]]}},"alternative-id":["S0143400408000155"],"URL":"https:\/\/doi.org\/10.1016\/j.placenta.2008.01.001","relation":{},"ISSN":["0143-4004"],"issn-type":[{"value":"0143-4004","type":"print"}],"subject":[],"published":{"date-parts":[[2008,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Placental Mesenchymal Dysplasia with Beckwith\u2013Wiedemann Syndrome Fetus in the Context of Biparental and Androgenic Cell Lines","name":"articletitle","label":"Article Title"},{"value":"Placenta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.placenta.2008.01.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2008 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}