{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T05:12:24Z","timestamp":1787807544725,"version":"build-2784847793"},"reference-count":30,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2008,7,1]],"date-time":"2008-07-01T00:00:00Z","timestamp":1214870400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,7,1]],"date-time":"2008-07-01T00:00:00Z","timestamp":1214870400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Placenta"],"published-print":{"date-parts":[[2008,7]]},"DOI":"10.1016\/j.placenta.2008.04.005","type":"journal-article","created":{"date-parts":[[2008,5,29]],"date-time":"2008-05-29T05:36:50Z","timestamp":1212039410000},"page":"614-623","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":57,"title":["Endovascular Trophoblast Invasion, Spiral Artery Remodelling and Uteroplacental Haemodynamics in a Transgenic Rat Model of Pre-eclampsia"],"prefix":"10.1016","volume":"29","author":[{"given":"N.","family":"Geusens","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Verlohren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Luyten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Taube","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Hering","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Vercruysse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Hanssens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.W.","family":"Dudenhausen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Dechend","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Pijnenborg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.placenta.2008.04.005_bib1","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1111\/j.1471-0528.1953.tb07668.x","article-title":"The maternal placental blood flow in normotensive and hypertensive women","volume":"60","author":"Browne","year":"1953","journal-title":"J Obstet Gynaecol Br Emp"},{"key":"10.1016\/j.placenta.2008.04.005_bib2","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/0028-2243(84)90047-9","article-title":"The making of the placental bed","volume":"18","author":"Robertson","year":"1984","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.placenta.2008.04.005_bib3","first-page":"177","article-title":"The role of the spiral arteries in the pathogenesis of preeclampsia","volume":"1","author":"Brosens","year":"1972","journal-title":"Obstet Gynecol Annu"},{"key":"10.1016\/j.placenta.2008.04.005_bib4","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1016\/j.placenta.2005.12.006","article-title":"The uterine spiral arteries in human pregnancy: facts and controversies","volume":"27","author":"Pijnenborg","year":"2006","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2008.04.005_bib5","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/S0140-6736(83)91970-0","article-title":"New Doppler technique for assessing uteroplacental blood flow","volume":"1","author":"Campbell","year":"1983","journal-title":"Lancet"},{"key":"10.1016\/j.placenta.2008.04.005_bib6","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1080\/jmf.12.2.78.88","article-title":"Second-trimester uterine artery Doppler screening in unselected populations: a review","volume":"12","author":"Papageorghiou","year":"2002","journal-title":"J Matern Fetal Neonatal Med"},{"key":"10.1016\/j.placenta.2008.04.005_bib7","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/0143-4004(88)90055-0","article-title":"Doppler blood flow in pregnancy","volume":"9","author":"McParland","year":"1988","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2008.04.005_bib8","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1515\/jpme.1992.20.2.139","article-title":"Doppler flow measurements and histomorphology of the placental bed in uteroplacental insufficiency","volume":"20","author":"Voigt","year":"1992","journal-title":"J Perinat Med"},{"key":"10.1016\/j.placenta.2008.04.005_bib9","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1111\/j.1479-828X.1999.tb03407.x","article-title":"The comparison of uterine artery Doppler velocimetry with the histopathology of the placental bed","volume":"39","author":"Sagol","year":"1999","journal-title":"Aust N Z J Obstet Gynaecol"},{"key":"10.1016\/j.placenta.2008.04.005_bib10","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1053\/plac.2001.0676","article-title":"Uterine artery Doppler flow and uteroplacental vascular pathology in normal pregnancies and pregnancies complicated by pre-eclampsia and small for gestational age fetuses","volume":"22","author":"Aardema","year":"2001","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2008.04.005_bib11","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.placenta.2004.11.004","article-title":"Interstitial trophoblast invasion in the decidua and mesometrial triangle during the last third of pregnancy in the rat","volume":"27","author":"Vercruysse","year":"2006","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2008.04.005_bib12","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1016\/j.placenta.2004.09.007","article-title":"Endovascular trophoblast invasion and associated structural changes in uterine spiral arteries of the pregnant rat","volume":"26","author":"Caluwaerts","year":"2005","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2008.04.005_bib13","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/S0146-0005(99)80055-X","article-title":"Animal models of preeclampsia","volume":"23","author":"Podjarny","year":"1999","journal-title":"Semin Perinatol"},{"key":"10.1016\/j.placenta.2008.04.005_bib14","doi-asserted-by":"crossref","first-page":"2056","DOI":"10.1681\/ASN.V11112056","article-title":"Rats transgenic for human renin and human angiotensinogen as a model for gestational hypertension","volume":"11","author":"Bohlender","year":"2000","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.placenta.2008.04.005_bib15","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1161\/01.HYP.0000154785.50570.63","article-title":"Agonistic autoantibodies to the AT1 receptor in a transgenic rat model of preeclampsia","volume":"45","author":"Dechend","year":"2005","journal-title":"Hypertension"},{"key":"10.1016\/j.placenta.2008.04.005_bib16","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1177\/42.8.8027531","article-title":"A simple technique for preservation of fixation-sensitive antigens in paraffin-embedded tissues","volume":"42","author":"Beckstead","year":"1994","journal-title":"J Histochem Cytochem"},{"key":"10.1016\/j.placenta.2008.04.005_bib17","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1177\/39.10.1682362","article-title":"An in situ hybridization histochemistry method for the use of alkaline phosphatase-labeled oligonucleotide probes in small intestine","volume":"39","author":"Kiyama","year":"1991","journal-title":"J Histochem Cytochem"},{"issue":"2","key":"10.1016\/j.placenta.2008.04.005_bib18","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1161\/HYPERTENSIONAHA.107.103176","article-title":"Uterine vascular function in a transgenic preeclampsia rat model","volume":"51","author":"Verlohren","year":"2008","journal-title":"Hypertension"},{"key":"10.1016\/j.placenta.2008.04.005_bib19","first-page":"11","article-title":"In vivo analysis of trophoblast cell invasion in the human","volume":"122","author":"Pijnenborg","year":"2006","journal-title":"Methods Mol Med"},{"key":"10.1016\/j.placenta.2008.04.005_bib20","series-title":"Chesley's hypertensive disorders in pregnancy","first-page":"43","article-title":"Epidemiology of hypertension","author":"Ness","year":"1999"},{"key":"10.1016\/j.placenta.2008.04.005_bib21","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1210\/me.2004-0158","article-title":"Differential roles of renin and angiotensinogen in the feto-maternal interface in the development of complications of pregnancy","volume":"19","author":"Takimoto-Ohnishi","year":"2005","journal-title":"Mol Endocrinol"},{"key":"10.1016\/j.placenta.2008.04.005_bib22","doi-asserted-by":"crossref","DOI":"10.1007\/BF01464333","article-title":"Renin-like immunoreactivity in human placenta and fetal membranes","volume":"104","author":"Hanssens","year":"1995","journal-title":"Histochem Cell Biol"},{"key":"10.1016\/j.placenta.2008.04.005_bib23","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0301-2115(98)00187-0","article-title":"Renin-like immunoreactivity in uterus and placenta from normotensive and hypertensive pregnancies","volume":"81","author":"Hanssens","year":"1998","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.placenta.2008.04.005_bib24","doi-asserted-by":"crossref","first-page":"H1421","DOI":"10.1152\/ajpheart.00031.2006","article-title":"Developmental changes in hemodynamics of uterine artery, utero- and umbilicoplacental, and vitelline circulations in mouse throughout gestation","volume":"291","author":"Mu","year":"2006","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.placenta.2008.04.005_bib25","doi-asserted-by":"crossref","first-page":"2139","DOI":"10.1172\/JCI119387","article-title":"Human cytotrophoblasts adopt a vascular phenotype as they differentiate. A strategy for successful endovascular invasion?","volume":"99","author":"Zhou","year":"1997","journal-title":"J Clin Invest"},{"issue":"1","key":"10.1016\/j.placenta.2008.04.005_bib26","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1096\/fasebj.14.1.208","article-title":"Hemeoxygenase expression in human placenta and placental bed implies a role in regulation of trophoblast invasion and placental function","volume":"14","author":"Lyall","year":"2000","journal-title":"FASEB J"},{"key":"10.1016\/j.placenta.2008.04.005_bib27","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1084\/jem.186.4.517","article-title":"Endothelial-dependent mechanisms regulate leukocyte transmigration: a process involving the proteasome and disruption of the vascular endothelial-cadherin complex at endothelial cell-to-cell junctions","volume":"186","author":"Allport","year":"1997","journal-title":"J Exp Med"},{"key":"10.1016\/j.placenta.2008.04.005_bib28","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1002\/path.1700930219","article-title":"The pathological response of the vessels of the placental bed to hypertensive pregnancy","volume":"93","author":"Robertson","year":"1967","journal-title":"J Pathol Bacteriol"},{"key":"10.1016\/j.placenta.2008.04.005_bib29","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1111\/j.1471-0528.1972.tb12922.x","article-title":"On the pathogenesis of placental infarcts in pre-eclampsia","volume":"79","author":"Brosens","year":"1972","journal-title":"J Obstet Gynaecol Br Commonw"},{"key":"10.1016\/j.placenta.2008.04.005_bib30","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1111\/j.1471-0528.1994.tb13182.x","article-title":"A study of placental bed spiral arteries and trophoblast invasion in normal and severe pre-eclamptic pregnancies","volume":"101","author":"Meekins","year":"1994","journal-title":"Br J Obstet Gynaecol"}],"container-title":["Placenta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400408001331?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400408001331?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T17:38:09Z","timestamp":1758908289000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0143400408001331"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,7]]},"references-count":30,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2008,7]]}},"alternative-id":["S0143400408001331"],"URL":"https:\/\/doi.org\/10.1016\/j.placenta.2008.04.005","relation":{},"ISSN":["0143-4004"],"issn-type":[{"value":"0143-4004","type":"print"}],"subject":[],"published":{"date-parts":[[2008,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Endovascular Trophoblast Invasion, Spiral Artery Remodelling and Uteroplacental Haemodynamics in a Transgenic Rat Model of Pre-eclampsia","name":"articletitle","label":"Article Title"},{"value":"Placenta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.placenta.2008.04.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2008 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}