{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T07:22:34Z","timestamp":1780730554362,"version":"3.54.1"},"reference-count":50,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Placenta"],"published-print":{"date-parts":[[2013,1]]},"DOI":"10.1016\/j.placenta.2012.10.016","type":"journal-article","created":{"date-parts":[[2012,11,22]],"date-time":"2012-11-22T06:31:11Z","timestamp":1353565871000},"page":"35-41","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"title":["Lack of activation of peripheral blood dendritic cells in human pregnancies complicated by intrauterine growth restriction"],"prefix":"10.1016","volume":"34","author":[{"given":"M.","family":"Cappelletti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Giannelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Martinelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Cetin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Colombo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Calcaterra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Mavilio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Della Bella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.placenta.2012.10.016_bib1","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1196\/annals.1434.006","article-title":"Inflammation and pregnancy \u2013 the role of toll-like receptors in trophoblast-immune interaction","volume":"1127","author":"Mor","year":"2008","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.placenta.2012.10.016_bib2","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1111\/j.1600-0897.2009.00792.x","article-title":"Inflammation and implantation","volume":"63","author":"Dekel","year":"2010","journal-title":"Am J Reprod Immunol"},{"key":"10.1016\/j.placenta.2012.10.016_bib3","doi-asserted-by":"crossref","first-page":"141.e1","DOI":"10.1016\/j.ajog.2012.05.025","article-title":"Proangiogenic immature myeloid cells populate the human placenta and their presence correlates with placental and birth weight","volume":"207","author":"Mei-Dan","year":"2012","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.placenta.2012.10.016_bib4","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1038\/nm1452","article-title":"Decidual NK cells regulate key developmental processes at the human fetal-maternal interface","volume":"12","author":"Hanna","year":"2006","journal-title":"Nat Med"},{"key":"10.1016\/j.placenta.2012.10.016_bib5","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1095\/biolreprod.103.017574","article-title":"Dendritic cells in the human decidua","volume":"69","author":"Gardner","year":"2003","journal-title":"Biol Reprod"},{"key":"10.1016\/j.placenta.2012.10.016_bib6","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.imlet.2007.09.014","article-title":"Fetal tolerance in human pregnancy \u2013 a crucial balance between acceptance and limitation of trophoblast invasion","volume":"115","author":"Von Rango","year":"2008","journal-title":"Immunol Lett"},{"key":"10.1016\/j.placenta.2012.10.016_bib7","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.siny.2006.04.001","article-title":"Inflammation and pre-eclampsia","volume":"11","author":"Borzychowski","year":"2006","journal-title":"Semin Fetal Neonat Med"},{"key":"10.1016\/j.placenta.2012.10.016_bib8","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.it.2006.06.009","article-title":"NK cells and human pregnancy\u2013an inflammatory view","volume":"27","author":"Sargent","year":"2006","journal-title":"Trends Immunol"},{"key":"10.1016\/j.placenta.2012.10.016_bib9","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1038\/nature06175","article-title":"Taking dendritic cells into medicine","volume":"449","author":"Steinman","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.placenta.2012.10.016_bib10","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1586\/1744666X.3.3.411","article-title":"Disarming dendritic cells: a tumor strategy to escape from immune control?","volume":"3","author":"Della Bella","year":"2007","journal-title":"Expert Rev Clin Immunol"},{"key":"10.1016\/j.placenta.2012.10.016_bib11","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1080\/08820130802191334","article-title":"Role of dendritic cells in the regulation of maternal immune responses to the fetus during mammalian gestation","volume":"37","author":"Kammerer","year":"2008","journal-title":"Immunol Invest"},{"key":"10.1016\/j.placenta.2012.10.016_bib12","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1095\/biolreprod.107.060632","article-title":"Dendritic cells: key to fetal tolerance?","volume":"77","author":"Blois","year":"2007","journal-title":"Biol Reprod"},{"key":"10.1016\/j.placenta.2012.10.016_bib13","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1111\/j.1365-2249.2011.04330.x","article-title":"Incomplete activation of peripheral blood dendritic cells during healthy human pregnancy","volume":"164","author":"Della Bella","year":"2011","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.placenta.2012.10.016_bib14","doi-asserted-by":"crossref","first-page":"S77","DOI":"10.1016\/j.placenta.2008.12.006","article-title":"Intrauterine growth restriction: implications for placental metabolism and transport. A review","volume":"30","author":"Cetin","year":"2009","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2012.10.016_bib15","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1111\/j.1471-0528.2004.00273.x","article-title":"Fetal responses to placental insufficiency: an update","volume":"111","author":"Baschat","year":"2004","journal-title":"Br J Obstet Gynaecol"},{"key":"10.1016\/j.placenta.2012.10.016_bib16","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1203\/01.PDR.0000181381.82856.23","article-title":"Placental phenotypes of intrauterine growth","volume":"58","author":"Sibley","year":"2005","journal-title":"Pediatr Res"},{"key":"10.1016\/j.placenta.2012.10.016_bib17","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1148\/radiology.182.2.1732970","article-title":"Fetal crown-rump length: reevaluation of relation to menstrual age (5\u201318 weeks) with high resolution real-time US","volume":"182","author":"Hadlock","year":"1992","journal-title":"Radiology"},{"key":"10.1016\/j.placenta.2012.10.016_bib18","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1002\/jcu.1870150203","article-title":"Fitting growth curves to head and abdomen measurements of the fetus: a multicentric study","volume":"15","author":"Todros","year":"1987","journal-title":"J\u00a0Clin Ultrasound"},{"key":"10.1016\/j.placenta.2012.10.016_bib19","first-page":"203","article-title":"Standard di peso alla nascita in Italia","volume":"112","author":"Parazzini","year":"1991","journal-title":"Ann Ostet Ginecol Med Perinat"},{"key":"10.1016\/j.placenta.2012.10.016_bib20","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1002\/cyto.b.20434","article-title":"A\u00a0six-color flow cytometric assay for the analysis of peripheral blood dendritic cells","volume":"74","author":"Giannelli","year":"2008","journal-title":"Cytometry B Clin Cytom"},{"key":"10.1016\/j.placenta.2012.10.016_bib21","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.jim.2008.09.009","article-title":"Application of six-color flow cytometry for the assessment of dendritic cell responses in whole blood assays","volume":"339","author":"Della Bella","year":"2008","journal-title":"J\u00a0Immunol Methods"},{"key":"10.1016\/j.placenta.2012.10.016_bib22","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1016\/j.molimm.2007.07.020","article-title":"Keyhole limpet hemocyanin induces the activation and maturation of human dendritic cells through the involvement of mannose receptor","volume":"45","author":"Presicce","year":"2008","journal-title":"Mol Immunol"},{"key":"10.1016\/j.placenta.2012.10.016_bib23","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.clim.2006.01.011","article-title":"Quantitative and functional defects of dendritic cells in classic Kaposi's sarcoma","volume":"119","author":"Della Bella","year":"2006","journal-title":"Clin Immunol"},{"key":"10.1016\/j.placenta.2012.10.016_bib24","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1146\/annurev.immunol.23.021704.115633","article-title":"IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors","volume":"23","author":"Liu","year":"2005","journal-title":"Annu Rev Immunol"},{"key":"10.1016\/j.placenta.2012.10.016_bib25","doi-asserted-by":"crossref","first-page":"5535","DOI":"10.1158\/0008-5472.CAN-04-1272","article-title":"Dendritic cell subsets differentially regulate angiogenesis in human ovarian cancer","volume":"64","author":"Curiel","year":"2004","journal-title":"Cancer Res"},{"key":"10.1016\/j.placenta.2012.10.016_bib26","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.jri.2010.11.002","article-title":"Decidualization and angiogenesis in early pregnancy: unravelling the functions of DC and NK cells","volume":"88","author":"Blois","year":"2001","journal-title":"J\u00a0Reprod Immunol"},{"key":"10.1016\/j.placenta.2012.10.016_bib27","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.it.2010.05.004","article-title":"Trafficking properties of plasmacytoid dendritic cells in health and disease","volume":"31","author":"Sozzani","year":"2010","journal-title":"Trends Immunol"},{"key":"10.1016\/j.placenta.2012.10.016_bib28","doi-asserted-by":"crossref","first-page":"2669","DOI":"10.1093\/humrep\/den308","article-title":"Chemokine CXCL12 promotes the cross-talk between trophoblasts and decidual stromal cells in human first-trimester pregnancy","volume":"23","author":"Zhou","year":"2008","journal-title":"Hum Reprod"},{"key":"10.1016\/j.placenta.2012.10.016_bib29","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.placenta.2012.02.007","article-title":"Expression and regulation of chemerin during rat pregnancy","volume":"33","author":"Garces","year":"2012","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2012.10.016_bib30","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1038\/ni1141","article-title":"Plasmacytoid dendritic cells in immunity","volume":"5","author":"Colonna","year":"2004","journal-title":"Nat Immunol"},{"key":"10.1016\/j.placenta.2012.10.016_bib31","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1016\/0952-7915(90)90048-L","article-title":"The cytokine basis for cross-talk between the maternal immune and reproductive systems","volume":"2","author":"Wegmann","year":"1990","journal-title":"Curr Opin Immunol"},{"key":"10.1016\/j.placenta.2012.10.016_bib32","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1111\/j.1600-0897.1996.tb00011.x","article-title":"Aspirin-interleukin-3 interrelationships in patients with anti-phospholipid syndrome","volume":"35","author":"Fishman","year":"1996","journal-title":"Am J Reprod Immunol"},{"key":"10.1016\/j.placenta.2012.10.016_bib33","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1111\/j.1600-0897.2008.00619.x","article-title":"Distribution and maturity of dendritic cells in diseases of insufficient placentation","volume":"60","author":"Scholz","year":"2008","journal-title":"Am J Reprod Immunol"},{"key":"10.1016\/j.placenta.2012.10.016_bib34","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1056\/NEJMcibr1207279","article-title":"Inducing tolerance to pregnancy","volume":"367","author":"Williams","year":"2012","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.placenta.2012.10.016_bib35","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.jri.2009.07.011","article-title":"The impact of dendritic cells on angiogenic responses at the fetal-maternal interface","volume":"83","author":"Barrientos","year":"2009","journal-title":"J\u00a0Reprod Immunol"},{"key":"10.1016\/j.placenta.2012.10.016_bib36","doi-asserted-by":"crossref","first-page":"e32347","DOI":"10.1371\/journal.pone.0032347","article-title":"Pregnancy close to the edge: an immunosuppressive infiltrate in the chronic plate of placentas from uncomplicated egg cell donation","volume":"7","author":"Schonkeren","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1016\/j.placenta.2012.10.016_bib37","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/S1471-4906(02)00009-1","article-title":"The dual role of IL-10","volume":"24","author":"Mocellin","year":"2003","journal-title":"Trends Immunol"},{"key":"10.1016\/j.placenta.2012.10.016_bib38","doi-asserted-by":"crossref","first-page":"4020","DOI":"10.1182\/blood-2004-03-0885","article-title":"Are interleukin-16 and thrombopoietin new tools for the generation of dendritic cells?","volume":"104","author":"Della Bella","year":"2004","journal-title":"Blood"},{"key":"10.1016\/j.placenta.2012.10.016_bib39","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1093\/humrep\/der358","article-title":"MIC-1 (a multifunctional modulator of dendritic cell phenotype and function) is produced by decidual stromal cells and trophoblasts","volume":"27","author":"Segerer","year":"2012","journal-title":"Hum Reprod"},{"key":"10.1016\/j.placenta.2012.10.016_bib40","first-page":"40","article-title":"Shared and disparate components of the pathophysiologies of fetal growth restriction and preeclampsia","volume":"195","author":"Ness","year":"2006","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.placenta.2012.10.016_bib41","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.1016\/S0002-9378(13)90438-5","article-title":"Tumor necrosis factor-alpha in pregnancies associated with preeclampsia or small-for-gestational-age newborns","volume":"170","author":"Schiff","year":"1994","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.placenta.2012.10.016_bib42","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2010\/790605","article-title":"Circulating levels of inflammatory markers in intrauterine growth restriction","volume":"2010","author":"Boutsikou","year":"2010","journal-title":"Mediators Inflamm"},{"key":"10.1016\/j.placenta.2012.10.016_bib43","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.placenta.2012.01.004","article-title":"Myeloperoxidase in the plasma and placenta of normal pregnant women and women with pregnancies complicated by preeclampsia and intrauterine growth restriction","volume":"33","author":"Hung","year":"2012","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2012.10.016_bib44","doi-asserted-by":"crossref","first-page":"2061","DOI":"10.1182\/blood-2009-11-252940","article-title":"Thymic stromal lymphopoietin from trophoblasts induces dendritic cell-mediated regulatory Th2 bias in the decidua during early gestation in humans","volume":"116","author":"Guo","year":"2010","journal-title":"Blood"},{"key":"10.1016\/j.placenta.2012.10.016_bib45","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1164\/rccm.201001-0107OC","article-title":"Inhibition of allergic bronchial asthma by thrombomodulin is mediated by dendritic cells","volume":"183","author":"Takagi","year":"2011","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.placenta.2012.10.016_bib46","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1515\/JPM.2002.047","article-title":"Increased endothelial thrombomodulin (TM) expression in pregnancies complicated by IUGR","volume":"30","author":"Wienhard","year":"2002","journal-title":"J\u00a0Perinat Med"},{"key":"10.1016\/j.placenta.2012.10.016_bib47","first-page":"245","article-title":"Placental immunoregulation","volume":"6","author":"Hunziker","year":"1986","journal-title":"Crit Rev Immunol"},{"key":"10.1016\/j.placenta.2012.10.016_bib48","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.jri.2009.05.003","article-title":"Fetal-maternal HLA-C mismatch is associated with decidual T cell activation and induction of functional T regulatory cells","volume":"82","author":"Tilburgs","year":"2009","journal-title":"J\u00a0Reprod Immunol"},{"key":"10.1016\/j.placenta.2012.10.016_bib49","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1530\/REP-09-0007","article-title":"Altered decidual leukocyte populations in the placental bed in pre-eclampsia and foetal growth restriction: a comparison with late normal pregnancy","volume":"138","author":"Williams","year":"2009","journal-title":"Reproduction"},{"key":"10.1016\/j.placenta.2012.10.016_bib50","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1097\/01.AOG.0000167389.97019.37","article-title":"Immunogenetic determinants of preeclampsia and related pregnancy disorders","volume":"106","author":"Saftlas","year":"2005","journal-title":"Obstet Gynecol"}],"container-title":["Placenta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400412004092?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400412004092?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T17:47:33Z","timestamp":1758908853000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0143400412004092"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1]]},"references-count":50,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["S0143400412004092"],"URL":"https:\/\/doi.org\/10.1016\/j.placenta.2012.10.016","relation":{},"ISSN":["0143-4004"],"issn-type":[{"value":"0143-4004","type":"print"}],"subject":[],"published":{"date-parts":[[2013,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Lack of activation of peripheral blood dendritic cells in human pregnancies complicated by intrauterine growth restriction","name":"articletitle","label":"Article Title"},{"value":"Placenta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.placenta.2012.10.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}