{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T14:09:02Z","timestamp":1761919742218,"version":"3.44.0"},"reference-count":47,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2013,12,1]],"date-time":"2013-12-01T00:00:00Z","timestamp":1385856000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,12,1]],"date-time":"2013-12-01T00:00:00Z","timestamp":1385856000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Placenta"],"published-print":{"date-parts":[[2013,12]]},"DOI":"10.1016\/j.placenta.2013.10.006","type":"journal-article","created":{"date-parts":[[2013,10,15]],"date-time":"2013-10-15T22:41:54Z","timestamp":1381876914000},"page":"1142-1149","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"title":["Oxidatively modified LDL particles in the human placenta in early and late onset intrauterine growth restriction"],"prefix":"10.1016","volume":"34","author":[{"given":"U.","family":"Pecks","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Rath","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Caspers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Sosnowsky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Ziems","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.-J.","family":"Thiesen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Maass","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0784-1262","authenticated-orcid":false,"given":"B.","family":"Huppertz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"Suppl.\u00a0A","key":"10.1016\/j.placenta.2013.10.006_bib1","doi-asserted-by":"crossref","first-page":"S77","DOI":"10.1016\/j.placenta.2008.12.006","article-title":"Intrauterine growth restriction: implications for placental metabolism and transport. A review","volume":"30","author":"Cetin","year":"2009","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2013.10.006_bib2","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S0020-7292(00)90000-6","article-title":"Intrauterine growth restriction. Clinical management guidelines for obstetrician-gynecologists. American College of Obstetricians and Gynecologists","volume":"72","author":"ACOG","year":"2001","journal-title":"Int J Gynaecol Obstet"},{"issue":"111","key":"10.1016\/j.placenta.2013.10.006_bib3","first-page":"1253","article-title":"International small for gestational age advisory board consensus development conference statement: management of short children born small for gestational age","volume":"2003","author":"Lee","year":"2001","journal-title":"Pediatrics"},{"key":"10.1016\/j.placenta.2013.10.006_bib4","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1515\/JPM.2008.050","article-title":"Intrauterine restriction (IUGR)","volume":"36","author":"Mandruzzato","year":"2008","journal-title":"J\u00a0Perinat Med"},{"key":"10.1016\/j.placenta.2013.10.006_bib5","doi-asserted-by":"crossref","first-page":"35","DOI":"10.2307\/1602506","article-title":"The direct cost of low birth weight","volume":"5","author":"Lewit","year":"1995","journal-title":"Future Child"},{"key":"10.1016\/j.placenta.2013.10.006_bib6","doi-asserted-by":"crossref","first-page":"20","DOI":"10.12927\/hcq.2013.21121","article-title":"CIHI survey: hospital costs for preterm and small-for-gestational age babies in Canada","volume":"12","author":"Lim","year":"2009","journal-title":"Healthc Q"},{"key":"10.1016\/j.placenta.2013.10.006_bib7","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1136\/bmj.311.6998.171","article-title":"Fetal origins of coronary heart disease","volume":"311","author":"Barker","year":"1995","journal-title":"BMJ"},{"key":"10.1016\/j.placenta.2013.10.006_bib8","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1136\/bmj.319.7222.1403","article-title":"Growth in utero and during childhood among women who develop coronary heart disease: longitudinal study","volume":"319","author":"Forsen","year":"1999","journal-title":"BMJ"},{"key":"10.1016\/j.placenta.2013.10.006_bib9","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1161\/CIRCULATIONAHA.107.710715","article-title":"Perinatal risk factors for ischemic heart disease: disentangling the roles of birth weight and preterm birth","volume":"117","author":"Kaijser","year":"2008","journal-title":"Circulation"},{"key":"10.1016\/j.placenta.2013.10.006_bib10","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1136\/bmj.38434.629630.E0","article-title":"Longitudinal study of birth weight and adult body mass index in predicting risk of coronary heart disease and stroke in women","volume":"330","author":"Rich-Edwards","year":"2005","journal-title":"BMJ"},{"key":"10.1016\/j.placenta.2013.10.006_bib11","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1053\/plac.1999.0395","article-title":"Uterine doppler velocimetry and placental hypoxic-ischemic lesion in pregnancies with fetal intrauterine growth restriction","volume":"20","author":"Ferrazzi","year":"1999","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2013.10.006_bib12","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1515\/JPM.2006.052","article-title":"Altered protease expression by periarterial trophoblast cells in severe early-onset preeclampsia with IUGR","volume":"34","author":"Reister","year":"2006","journal-title":"J\u00a0Perinat Med"},{"key":"10.1016\/j.placenta.2013.10.006_bib13","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1159\/000106488","article-title":"Role of oxidative stress in intrauterine growth restriction","volume":"64","author":"Biri","year":"2007","journal-title":"Gynecol Obstet Invest"},{"key":"10.1016\/j.placenta.2013.10.006_bib14","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/j.placenta.2009.02.009","article-title":"Rheological and physiological consequences of conversion of the maternal spiral arteries for uteroplacental blood flow during human pregnancy","volume":"30","author":"Burton","year":"2009","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2013.10.006_bib15","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1161\/HYPERTENSIONAHA.107.107607","article-title":"Placental origins of preeclampsia: challenging the current hypothesis","volume":"51","author":"Huppertz","year":"2008","journal-title":"Hypertension"},{"key":"10.1016\/j.placenta.2013.10.006_bib16","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1111\/j.1600-0897.1985.tb00344.x","article-title":"Immunohistochemical findings in acute atherosis associated with intrauterine growth retardation","volume":"7","author":"Labarrere","year":"1985","journal-title":"Am J Reprod Immunol Microbiol"},{"key":"10.1016\/j.placenta.2013.10.006_bib17","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1111\/j.1471-0528.1976.tb00781.x","article-title":"The ultrastructure of the arterial supply of the human placenta in pregnancy complicated by fetal growth retardation","volume":"83","author":"Sheppard","year":"1976","journal-title":"Br J Obstet Gynaecol"},{"key":"10.1016\/j.placenta.2013.10.006_bib18","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1089\/ars.2009.2733","article-title":"diversity, patterns of recognition, and pathophysiology","volume":"13","author":"Levitan","year":"2010","journal-title":"Antioxid Redox Signal"},{"key":"10.1016\/j.placenta.2013.10.006_bib19","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1111\/j.1600-0897.2012.01157.x","article-title":"Anti-oxidized low-density lipoprotein (oxLDL) antibody levels are not related to increasing circulating oxLDL concentrations during the course of pregnancy","volume":"68","author":"Pecks","year":"2012","journal-title":"Am J Reprod Immunol"},{"key":"10.1016\/j.placenta.2013.10.006_bib20","first-page":"2483","article-title":"Lipoprotein subfraction changes in normal pregnancy: threshold effect of plasma triglyceride on appearance of small, dense low density lipoprotein","volume":"82","author":"Sattar","year":"1997","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.placenta.2013.10.006_bib21","doi-asserted-by":"crossref","first-page":"4543","DOI":"10.1210\/jcem.85.12.7027","article-title":"Low density lipoprotein (LDL) subfractions during pregnancy: accumulation of buoyant LDL with advancing gestation","volume":"85","author":"Winkler","year":"2000","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.placenta.2013.10.006_bib22","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1194\/jlr.M800538-JLR200","article-title":"Transport of maternal cholesterol to the fetus is affected by maternal plasma cholesterol concentrations in the golden Syrian hamster","volume":"50","author":"Burke","year":"2009","journal-title":"J\u00a0Lipid Res"},{"key":"10.1016\/j.placenta.2013.10.006_bib23","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1161\/CIRCRESAHA.108.185066","article-title":"Human endothelial cells of the placental barrier efficiently deliver cholesterol to the fetal circulation via ABCA1 and ABCG1","volume":"104","author":"Stefulj","year":"2009","journal-title":"Circ Res"},{"key":"10.1016\/j.placenta.2013.10.006_bib24","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1095\/biolreprod.112.102442","article-title":"The role of maternal-fetal cholesterol transport in early fetal life: current insights","volume":"88","author":"Baardman","year":"2013","journal-title":"Biol Reprod"},{"key":"10.1016\/j.placenta.2013.10.006_bib25","doi-asserted-by":"crossref","first-page":"156","DOI":"10.3109\/10641955.2010.544805","article-title":"The evaluation of the oxidative state of low-density lipoproteins in intrauterine growth restriction and preeclampsia","volume":"31","author":"Pecks","year":"2012","journal-title":"Hypertens Pregnancy"},{"key":"10.1016\/j.placenta.2013.10.006_bib26","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.atherosclerosis.2004.04.026","article-title":"Fetal cord plasma lipoprotein status in uncomplicated human pregnancies and in pregnancies complicated by pre-eclampsia and intrauterine growth restriction","volume":"176","author":"Rodie","year":"2004","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.placenta.2013.10.006_bib27","first-page":"128","article-title":"Lipid and lipoprotein concentrations in pregnancies complicated by intrauterine growth restriction","volume":"84","author":"Sattar","year":"1999","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.placenta.2013.10.006_bib28","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1515\/jpm.2011.135","article-title":"Maternal and fetal cord blood lipids in intrauterine growth restriction","volume":"40","author":"Pecks","year":"2012","journal-title":"J\u00a0Perinat Med"},{"key":"10.1016\/j.placenta.2013.10.006_bib29","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.2353\/ajpath.2007.070528","article-title":"Oxidative stress, gene expression, and protein changes induced in the human placenta during labor","volume":"171","author":"Cindrova-Davies","year":"2007","journal-title":"Am J Pathol"},{"key":"10.1016\/j.placenta.2013.10.006_bib30","doi-asserted-by":"crossref","first-page":"IX","DOI":"10.3109\/10641950109152635","article-title":"The classification and diagnosis of the hypertensive disorders of pregnancy: statement from the International Society for the Study of Hypertension in Pregnancy (ISSHP)","volume":"20","author":"Brown","year":"2001","journal-title":"Hypertens Pregnancy"},{"key":"10.1016\/j.placenta.2013.10.006_bib31","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1007\/s00418-006-0182-5","article-title":"Expression of the actin stress fiber-associated protein CLP36 in the human placenta","volume":"126","author":"Miehe","year":"2006","journal-title":"Histochem Cell Biol"},{"key":"10.1016\/j.placenta.2013.10.006_bib32","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1007\/s13361-010-0031-6","article-title":"Mass spectrometric characterization of protein structure details refines the proteome signature for invasive ductal breast carcinoma","volume":"22","author":"Rower","year":"2011","journal-title":"J\u00a0Am Soc Mass Spectrom"},{"key":"10.1016\/j.placenta.2013.10.006_bib33","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/0021-9150(94)05404-7","article-title":"Metabolism of modified LDL by cultured human placental cells","volume":"112","author":"Bonet","year":"1995","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.placenta.2013.10.006_bib34","doi-asserted-by":"crossref","first-page":"862982","DOI":"10.1155\/2013\/862982","article-title":"Levels of oxidized LDL, estrogens and progesterone in placenta tissues and serum paraoxonase activity in preeclampsia","volume":"2013","author":"Acikgoz","year":"2013","journal-title":"Mediat Inflamm"},{"key":"10.1016\/j.placenta.2013.10.006_bib35","first-page":"220","article-title":"Determination of maternal and foetal serum lipid profile and placental oxidised low density lipoprotein accumulation in preeclampsia and normotensive pregnancies","volume":"216","author":"Pecks","year":"2012","journal-title":"Z\u00a0Geburtshilfe Neonatol"},{"key":"10.1016\/j.placenta.2013.10.006_bib36","first-page":"578","article-title":"The correlation of arterial lesions with umbilical artery Doppler velocimetry in the placentas of small-for-dates pregnancies","volume":"75","author":"Fok","year":"1990","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.placenta.2013.10.006_bib37","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1016\/S0029-7844(97)00473-0","article-title":"Placental pathology of absent and reversed end-diastolic flow in growth-restricted fetuses","volume":"90","author":"Salafia","year":"1997","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.placenta.2013.10.006_bib38","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1194\/jlr.M500439-JLR200","article-title":"OxLDL increases endothelial stiffness, force generation, and network formation","volume":"47","author":"Byfield","year":"2006","journal-title":"J\u00a0Lipid Res"},{"key":"10.1016\/j.placenta.2013.10.006_bib39","doi-asserted-by":"crossref","first-page":"1969","DOI":"10.1210\/jc.2003-032042","article-title":"Oxidized low-density lipoproteins inhibit trophoblastic cell invasion","volume":"89","author":"Pavan","year":"2004","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.placenta.2013.10.006_bib40","doi-asserted-by":"crossref","first-page":"4583","DOI":"10.1210\/en.2003-1747","article-title":"Lipids from oxidized low-density lipoprotein modulate human trophoblast invasion: involvement of nuclear liver X receptors","volume":"145","author":"Pavan","year":"2004","journal-title":"Endocrinology"},{"key":"10.1016\/j.placenta.2013.10.006_bib41","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1016\/j.bbalip.2010.05.015","article-title":"Placental ABCA1 and ABCG1 transporters efflux cholesterol and protect trophoblasts from oxysterol induced toxicity","volume":"1801","author":"Aye","year":"2010","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.placenta.2013.10.006_bib42","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.cardiores.2005.07.003","article-title":"Oxidized LDL downregulates ATP-binding cassette transporter-1 in human vascular endothelial cells via inhibiting liver X receptor (LXR)","volume":"68","author":"Zhu","year":"2005","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.placenta.2013.10.006_bib43","doi-asserted-by":"crossref","first-page":"2680","DOI":"10.1172\/JCI119813","article-title":"Fatty streak formation occurs in human fetal aortas and is greatly enhanced by maternal hypercholesterolemia. Intimal accumulation of low density lipoprotein and its oxidation precede monocyte recruitment into early atherosclerotic lesions","volume":"100","author":"Napoli","year":"1997","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.placenta.2013.10.006_bib44","doi-asserted-by":"crossref","first-page":"1252","DOI":"10.1210\/mend-3-8-1252","article-title":"Expression of low density lipoprotein receptor gene in human placenta during pregnancy","volume":"3","author":"Furuhashi","year":"1989","journal-title":"Mol Endocrinol"},{"key":"10.1016\/j.placenta.2013.10.006_bib45","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1074\/mcp.M112.018192","article-title":"Longitudinal analysis of maternal plasma apolipoproteins in pregnancy: a targeted proteomics approach","volume":"12","author":"Flood-Nichols","year":"2012","journal-title":"Mol Cell Proteomics"},{"key":"10.1016\/j.placenta.2013.10.006_bib46","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1210\/endo.136.1.7828550","article-title":"Localization and regulation of the human very low density lipoprotein\/apolipoprotein-E receptor: trophoblast expression predicts a role for the receptor in placental lipid transport","volume":"136","author":"Wittmaack","year":"1995","journal-title":"Endocrinology"},{"key":"10.1016\/j.placenta.2013.10.006_bib47","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1530\/REP-12-0114","article-title":"Low abundance plasma proteins in labour","volume":"144","author":"Yuan","year":"2012","journal-title":"Reproduction"}],"container-title":["Placenta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400413007789?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400413007789?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T17:48:37Z","timestamp":1758908917000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0143400413007789"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12]]},"references-count":47,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2013,12]]}},"alternative-id":["S0143400413007789"],"URL":"https:\/\/doi.org\/10.1016\/j.placenta.2013.10.006","relation":{},"ISSN":["0143-4004"],"issn-type":[{"type":"print","value":"0143-4004"}],"subject":[],"published":{"date-parts":[[2013,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Oxidatively modified LDL particles in the human placenta in early and late onset intrauterine growth restriction","name":"articletitle","label":"Article Title"},{"value":"Placenta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.placenta.2013.10.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}