{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T19:41:15Z","timestamp":1786995675861,"version":"build-2736575974"},"reference-count":49,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100007162","name":"Guangdong Science and Technology Department","doi-asserted-by":"publisher","award":["2016A020210074"],"award-info":[{"award-number":["2016A020210074"]}],"id":[{"id":"10.13039\/501100007162","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007162","name":"Guangdong Science and Technology Department","doi-asserted-by":"publisher","award":["2016B020233006"],"award-info":[{"award-number":["2016B020233006"]}],"id":[{"id":"10.13039\/501100007162","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007162","name":"Guangdong Science and Technology Department","doi-asserted-by":"publisher","award":["2015TX01N081"],"award-info":[{"award-number":["2015TX01N081"]}],"id":[{"id":"10.13039\/501100007162","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Placenta"],"published-print":{"date-parts":[[2017,9]]},"DOI":"10.1016\/j.placenta.2017.06.010","type":"journal-article","created":{"date-parts":[[2017,6,16]],"date-time":"2017-06-16T05:16:03Z","timestamp":1497590163000},"page":"94-101","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"special_numbering":"C","title":["Birth weight, umbilical and placental traits in relation to neonatal loss in cloned pigs"],"prefix":"10.1016","volume":"57","author":[{"given":"Zheng","family":"Ao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dewu","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengfa","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhimin","family":"Yue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junsong","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gengyuan","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enqin","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zicong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenfang","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"29","key":"10.1016\/j.placenta.2017.06.010_bib1","doi-asserted-by":"crossref","first-page":"8874","DOI":"10.1073\/pnas.1501718112","article-title":"Artificial cloning of domestic animals","volume":"112","author":"Keefer","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"2","key":"10.1016\/j.placenta.2017.06.010_bib2","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.theriogenology.2010.08.012","article-title":"Effects of vascular endothelial growth factor on porcine preimplantation embryos produced by in\u00a0vitro fertilization and somatic cell nuclear transfer","volume":"75","author":"Biswas","year":"2011","journal-title":"Theriogenology"},{"issue":"SI","key":"10.1016\/j.placenta.2017.06.010_bib3","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1111\/j.1439-0531.2012.02121.x","article-title":"Somatic cell nuclear transfer cloning: practical applications and current legislation","volume":"475","author":"Niemann","year":"2012","journal-title":"Reprod. Domest. Anim."},{"key":"10.1016\/j.placenta.2017.06.010_bib4","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1186\/1471-2164-10-511","article-title":"Comparative proteomic analysis of malformed umbilical cords from somatic cell nuclear transfer-derived piglets: implications for early postnatal death","volume":"10","author":"Park","year":"2009","journal-title":"Bmc Genomics"},{"key":"10.1016\/j.placenta.2017.06.010_bib5","first-page":"245","article-title":"Genetically modified pigs for medicine and agriculture","volume":"25","author":"Prather","year":"2008","journal-title":"Biotechnol. Genet. Eng. Rev."},{"issue":"6","key":"10.1016\/j.placenta.2017.06.010_bib6","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1016\/j.theriogenology.2015.05.037","article-title":"Postmortem findings in cloned and transgenic piglets dead before weaning","volume":"84","author":"Schmidt","year":"2015","journal-title":"Theriogenology"},{"issue":"7","key":"10.1016\/j.placenta.2017.06.010_bib7","doi-asserted-by":"crossref","first-page":"1928","DOI":"10.1002\/pmic.200401079","article-title":"A\u00a0rare and often unrecognized cerebromeningitis and hemodynamic disorder: a major cause of sudden death in somatic cell cloned piglets","volume":"5","author":"Park","year":"2005","journal-title":"Proteomics"},{"issue":"6","key":"10.1016\/j.placenta.2017.06.010_bib8","doi-asserted-by":"crossref","first-page":"2647","DOI":"10.2527\/jas.2012-5531","article-title":"Postpartum deaths: piglet, placental, and umbilical characteristics","volume":"91","author":"Rootwelt","year":"2013","journal-title":"J.\u00a0Anim. Sci."},{"issue":"1","key":"10.1016\/j.placenta.2017.06.010_bib9","doi-asserted-by":"crossref","first-page":"144","DOI":"10.2527\/2005.831144x","article-title":"Preweaning piglet mortality in relation to placental efficiency","volume":"83","author":"van Rens","year":"2005","journal-title":"J.\u00a0Anim. Sci."},{"issue":"1\u20132","key":"10.1016\/j.placenta.2017.06.010_bib10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.anireprosci.2005.01.007","article-title":"Perinatal asphyxia pathophysiology in pig and human: a review","volume":"90","author":"Alonso-Spilsbury","year":"2005","journal-title":"Anim. Reprod. Sci."},{"key":"10.1016\/j.placenta.2017.06.010_bib11","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1186\/1472-6750-13-43","article-title":"Factors influencing the efficiency of generating genetically engineered pigs by nuclear transfer: multi-factorial analysis of a large data set","volume":"13","author":"Kurome","year":"2013","journal-title":"Bmc Biotechnol."},{"key":"10.1016\/j.placenta.2017.06.010_bib12","doi-asserted-by":"crossref","first-page":"S99","DOI":"10.1016\/j.placenta.2011.09.012","article-title":"Review: placental perturbations induce the developmental abnormalities often observed in bovine somatic cell nuclear transfer","volume":"33A","author":"Chavatte-Palmer","year":"2012","journal-title":"Placenta"},{"issue":"6","key":"10.1016\/j.placenta.2017.06.010_bib13","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1016\/j.theriogenology.2005.07.016","article-title":"Placental abnormalities associated with post-natal mortality in sheep somatic cell clones","volume":"65","author":"Loi","year":"2006","journal-title":"Theriogenology"},{"issue":"1","key":"10.1016\/j.placenta.2017.06.010_bib14","doi-asserted-by":"crossref","first-page":"e106663","DOI":"10.1371\/journal.pone.0106663","article-title":"Vascular alterations underlie developmental problems manifested in cloned cattle before or after birth","volume":"10","author":"Maiorka","year":"2015","journal-title":"PloS One"},{"issue":"4","key":"10.1016\/j.placenta.2017.06.010_bib15","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1016\/j.theriogenology.2007.04.060","article-title":"Placentation in cloned cattle: structure and microvascular architecture","volume":"68","author":"Miglino","year":"2007","journal-title":"Theriogenology"},{"key":"10.1016\/j.placenta.2017.06.010_bib16","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.anireprosci.2015.01.006","article-title":"Influence of embryo handling and transfer method on pig cloning efficiency","volume":"154","author":"Shi","year":"2015","journal-title":"Anim. Reprod. Sci."},{"issue":"1","key":"10.1016\/j.placenta.2017.06.010_bib17","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1089\/cell.2012.0042","article-title":"Effects of donor fibroblast cell type and transferred cloned embryo number on the efficiency of pig cloning","volume":"15","author":"Li","year":"2013","journal-title":"Cell Reprogr."},{"issue":"4","key":"10.1016\/j.placenta.2017.06.010_bib18","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1095\/biolreprod58.4.905","article-title":"Development of Meishan and Yorkshire littermate conceptuses in either a Meishan or Yorkshire uterine environment to day 90 of gestation and to term","volume":"58","author":"Wilson","year":"1998","journal-title":"Biol. Reprod."},{"issue":"7","key":"10.1016\/j.placenta.2017.06.010_bib19","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1016\/j.theriogenology.2010.05.026","article-title":"Pregnancies and piglets from large white sow recipients after two transfer methods of cloned and transgenic embryos of different pig breeds","volume":"74","author":"Schmidt","year":"2010","journal-title":"Theriogenology"},{"issue":"1","key":"10.1016\/j.placenta.2017.06.010_bib20","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1002\/biot.201400193","article-title":"Improving livestock for agriculture - technological progress from random transgenesis to precision genome editing heralds a new era","volume":"10","author":"Laible","year":"2015","journal-title":"Biotechnol. J."},{"issue":"1","key":"10.1016\/j.placenta.2017.06.010_bib21","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1095\/biolreprod.106.051581","article-title":"Large offspring or large placenta syndrome? Morphometric analysis of late gestation bovine placentomes from somatic nuclear transfer pregnancies complicated by hydrallantois","volume":"75","author":"Constant","year":"2006","journal-title":"Biol. Reprod."},{"issue":"5\u20136","key":"10.1016\/j.placenta.2017.06.010_bib22","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/j.placenta.2006.08.003","article-title":"Placental abnormalities in ovine somatic cell clones at term: a light and electron microscopic investigation","volume":"28","author":"Palmieri","year":"2007","journal-title":"Placenta"},{"issue":"6","key":"10.1016\/j.placenta.2017.06.010_bib23","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.1095\/biolreprod65.6.1813","article-title":"Placentomegaly in cloned mouse concepti caused by expansion of the spongiotrophoblast layer","volume":"65","author":"Tanaka","year":"2001","journal-title":"Biol. Reprod."},{"issue":"1","key":"10.1016\/j.placenta.2017.06.010_bib24","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.bbrc.2006.08.057","article-title":"Chorioallantoic placenta defects in cloned mice","volume":"349","author":"Wakisaka-Saito","year":"2006","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"6","key":"10.1016\/j.placenta.2017.06.010_bib25","doi-asserted-by":"crossref","first-page":"1573","DOI":"10.1016\/j.theriogenology.2016.05.017","article-title":"Placental abnormalities in equine pregnancies generated by SCNT from one donor horse","volume":"86","author":"Pozor","year":"2016","journal-title":"Theriogenology"},{"issue":"2","key":"10.1016\/j.placenta.2017.06.010_bib26","doi-asserted-by":"crossref","first-page":"177","DOI":"10.4161\/epi.6.2.13519","article-title":"DNA methylation in porcine preimplantation embryos developed in\u00a0vivo and produced by in\u00a0vitro fertilization, parthenogenetic activation and somatic cell nuclear transfer","volume":"6","author":"Deshmukh","year":"2011","journal-title":"Epigenet.-Us"},{"issue":"Suppl 2","key":"10.1016\/j.placenta.2017.06.010_bib27","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1111\/j.1439-0531.2008.01178.x","article-title":"Epigenetic regulation of foetal development in nuclear transfer animal models","volume":"43","author":"Dinnyes","year":"2008","journal-title":"Reprod. Domest. Anim."},{"issue":"9","key":"10.1016\/j.placenta.2017.06.010_bib28","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1074\/mcp.M500427-MCP200","article-title":"Proteomic analysis of the extraembryonic tissue from cloned porcine embryos","volume":"5","author":"Chae","year":"2006","journal-title":"Mol. Cell Proteom."},{"issue":"2","key":"10.1016\/j.placenta.2017.06.010_bib29","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.theriogenology.2008.07.025","article-title":"Abnormal gene expression in extraembryonic tissue from cloned porcine embryos","volume":"71","author":"Chae","year":"2009","journal-title":"Theriogenology"},{"issue":"3","key":"10.1016\/j.placenta.2017.06.010_bib30","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1093\/humupd\/dmq052","article-title":"Epigenetics and the placenta","volume":"17","author":"Nelissen","year":"2011","journal-title":"Hum. Reprod. Update"},{"issue":"11\u201312","key":"10.1016\/j.placenta.2017.06.010_bib31","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1016\/j.placenta.2005.12.001","article-title":"Characterization of the placenta specific bovine mammalian achaete scute-like homologue 2 (Mash2) gene","volume":"27","author":"Arnold","year":"2006","journal-title":"Placenta"},{"issue":"1","key":"10.1016\/j.placenta.2017.06.010_bib32","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.pbiomolbio.2010.11.005","article-title":"Imprinted genes and the epigenetic regulation of placental phenotype","volume":"106","author":"Fowden","year":"2011","journal-title":"Prog. Biophys. Mol. Biol."},{"issue":"6","key":"10.1016\/j.placenta.2017.06.010_bib33","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/j.placenta.2010.03.004","article-title":"Abnormal expression of the imprinted gene Phlda2 in cloned bovine placenta","volume":"31","author":"Guillomot","year":"2010","journal-title":"Placenta"},{"issue":"Suppl A","key":"10.1016\/j.placenta.2017.06.010_bib34","doi-asserted-by":"crossref","first-page":"S10","DOI":"10.1016\/j.placenta.2004.12.009","article-title":"Imprinted genes in the placenta\u2013a review","volume":"26","author":"Coan","year":"2005","journal-title":"Placenta"},{"issue":"5553","key":"10.1016\/j.placenta.2017.06.010_bib35","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1126\/science.295.5553.297","article-title":"Faithful expression of imprinted genes in cloned mice","volume":"295","author":"Inoue","year":"2002","journal-title":"Science"},{"issue":"2","key":"10.1016\/j.placenta.2017.06.010_bib36","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1089\/cell.2009.0090","article-title":"Aberrant expression and methylation status of putatively imprinted genes in placenta of cloned piglets","volume":"12","author":"Wei","year":"2010","journal-title":"Cell Reprogr."},{"issue":"6","key":"10.1016\/j.placenta.2017.06.010_bib37","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/j.placenta.2010.03.004","article-title":"Abnormal expression of the imprinted gene Phlda2 in cloned bovine placenta","volume":"31","author":"Guillomot","year":"2010","journal-title":"Placenta"},{"issue":"8","key":"10.1016\/j.placenta.2017.06.010_bib38","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1002\/pmic.200601045","article-title":"Comparative proteomic analysis associated with term placental insufficiency in cloned pig","volume":"7","author":"Lee","year":"2007","journal-title":"Proteomics"},{"key":"10.1016\/j.placenta.2017.06.010_bib39","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1146\/annurev.cellbio.15.1.269","article-title":"Biochemical pathways of caspase activation during apoptosis","volume":"15","author":"Budihardjo","year":"1999","journal-title":"Annu. Rev. Cell Dev. Bi"},{"issue":"4","key":"10.1016\/j.placenta.2017.06.010_bib40","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1007\/s00418-004-0677-x","article-title":"Oxidative stress in the placenta","volume":"122","author":"Myatt","year":"2004","journal-title":"Histochem Cell Biol."},{"issue":"2","key":"10.1016\/j.placenta.2017.06.010_bib41","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1017\/S1357729800054096","article-title":"Estimation of colostrum intake in the neonatal pig","volume":"78","author":"Devillers","year":"2004","journal-title":"Anim. Sci."},{"issue":"6","key":"10.1016\/j.placenta.2017.06.010_bib42","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/j.theriogenology.2007.12.007","article-title":"Investigating the behavioural and physiological indicators of neonatal survival in pigs","volume":"69","author":"Baxter","year":"2008","journal-title":"Theriogenology"},{"issue":"6","key":"10.1016\/j.placenta.2017.06.010_bib43","doi-asserted-by":"crossref","first-page":"2647","DOI":"10.2527\/jas.2012-5531","article-title":"Postpartum deaths: piglet, placental, and umbilical characteristics","volume":"91","author":"Rootwelt","year":"2013","journal-title":"J.\u00a0Anim. Sci."},{"issue":"1","key":"10.1016\/j.placenta.2017.06.010_bib44","doi-asserted-by":"crossref","first-page":"144","DOI":"10.2527\/2005.831144x","article-title":"Preweaning piglet mortality in relation to placental efficiency","volume":"83","author":"van Rens","year":"2005","journal-title":"J.\u00a0Anim. Sci."},{"issue":"3","key":"10.1016\/j.placenta.2017.06.010_bib45","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1038\/ng1973","article-title":"Nuclear reprogramming of cloned embryos and its implications for therapeutic cloning","volume":"39","author":"Yang","year":"2007","journal-title":"Nat. Genet."},{"issue":"6","key":"10.1016\/j.placenta.2017.06.010_bib46","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.placenta.2010.03.005","article-title":"The effect of intrauterine growth retardation on the expression of developmental factors in porcine placenta subsequent to the initiation of placentation","volume":"31","author":"Blomberg","year":"2010","journal-title":"Placenta"},{"issue":"6","key":"10.1016\/j.placenta.2017.06.010_bib47","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1354\/vp.45-6-865","article-title":"Review paper: a review of the pathology of abnormal placentae of somatic cell nuclear transfer clone pregnancies in cattle, sheep, and mice","volume":"45","author":"Palmieri","year":"2008","journal-title":"Vet. Pathol."},{"issue":"4","key":"10.1016\/j.placenta.2017.06.010_bib48","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1124\/pr.56.4.3","article-title":"Vascular endothelial growth factor and angiogenesis","volume":"56","author":"Hoeben","year":"2004","journal-title":"Pharmacol. Rev."},{"issue":"4","key":"10.1016\/j.placenta.2017.06.010_bib49","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1634\/stemcells.2005-0350","article-title":"Epigenetic modification is central to genome reprogramming in somatic cell nuclear transfer","volume":"24","author":"Armstrong","year":"2006","journal-title":"Stem Cells"}],"container-title":["Placenta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400417303065?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400417303065?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T17:56:11Z","timestamp":1758909371000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0143400417303065"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9]]},"references-count":49,"alternative-id":["S0143400417303065"],"URL":"https:\/\/doi.org\/10.1016\/j.placenta.2017.06.010","relation":{},"ISSN":["0143-4004"],"issn-type":[{"value":"0143-4004","type":"print"}],"subject":[],"published":{"date-parts":[[2017,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Birth weight, umbilical and placental traits in relation to neonatal loss in cloned pigs","name":"articletitle","label":"Article Title"},{"value":"Placenta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.placenta.2017.06.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}