{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T12:19:52Z","timestamp":1784895592031,"version":"3.55.0"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Jeanne and Jean-Louis L\u00e9vesque Perinatal Research Chair, Universit\u00e9 Laval"},{"DOI":"10.13039\/501100000156","name":"Fonds de recherche du Qu\u00e9bec - Sant\u00e9","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000156","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Jeanne et Jean-Louis L\u00e9vesque Foundation"},{"name":"Jeanne et Jean-Louis L\u00e9vesque Perinatal Research Chair at Universit\u00e9 Laval"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Placenta"],"published-print":{"date-parts":[[2017,9]]},"DOI":"10.1016\/j.placenta.2017.06.016","type":"journal-article","created":{"date-parts":[[2017,6,19]],"date-time":"2017-06-19T23:31:20Z","timestamp":1497915080000},"page":"123-128","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":31,"special_numbering":"C","title":["First-trimester placental thickness and the risk of preeclampsia or SGA"],"prefix":"10.1016","volume":"57","author":[{"given":"Chantale","family":"Vachon-Marceau","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzanne","family":"Demers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0754-4161","authenticated-orcid":false,"given":"St\u00e9phanie","family":"Markey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nan","family":"Okun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Girard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Kingdom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6936-4369","authenticated-orcid":false,"given":"Emmanuel","family":"Bujold","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.placenta.2017.06.016_bib1","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/0143-4004(88)90072-0","article-title":"Intrauterine growth retardation: morphometry of the microvillous membrane of the human placenta","volume":"9","author":"Teasdale","year":"1988","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2017.06.016_bib2","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1053\/plac.2001.0676","article-title":"Uterine artery Doppler flow and uteroplacental vascular pathology in normal pregnancies and pregnancies complicated by pre-eclampsia and small for gestational age fetuses","volume":"22","author":"Aardema","year":"2001","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2017.06.016_bib3","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1067\/S0002-9378(03)00576-3","article-title":"The frequency and severity of placental findings in women with preeclampsia are gestational age dependent","volume":"189","author":"Moldenhauer","year":"2003","journal-title":"Am. J. Obstet. Gynecol."},{"issue":"330","key":"10.1016\/j.placenta.2017.06.016_bib4","first-page":"e1","article-title":"Determinants of adverse perinatal outcome in high-risk women with abnormal uterine artery Doppler images","volume":"198","author":"Toal","year":"2008","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.placenta.2017.06.016_bib5","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/j.placenta.2005.06.002","article-title":"Pre-eclampsia and fetal growth restriction: how morphometrically different is the placenta?","volume":"27","author":"Egbor","year":"2006","journal-title":"Placenta"},{"issue":"561","key":"10.1016\/j.placenta.2017.06.016_bib6","first-page":"e1","article-title":"Placental vascular lesion differences in pregnancy-induced hypertension and normotensive fetal growth restriction","volume":"202","author":"Kovo","year":"2010","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.placenta.2017.06.016_bib7","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1016\/j.placenta.2012.03.011","article-title":"Sex-specific basis of severe placental dysfunction leading to extreme preterm delivery","volume":"33","author":"Walker","year":"2012","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2017.06.016_bib8","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1159\/000341712","article-title":"Combined screening for preeclampsia and small for gestational age at 11-13 weeks","volume":"33","author":"Poon","year":"2013","journal-title":"Fetal Diagn Ther."},{"issue":"383","key":"10.1016\/j.placenta.2017.06.016_bib9","first-page":"e1","article-title":"Screening for preeclampsia using first-trimester serum markers and uterine artery Doppler in nulliparous women","volume":"203","author":"Audibert","year":"2010","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.placenta.2017.06.016_bib10","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1373\/clinchem.2009.134080","article-title":"Combining biochemical and ultrasonographic markers in predicting preeclampsia: a systematic review","volume":"56","author":"Giguere","year":"2010","journal-title":"Clin. Chem."},{"key":"10.1016\/j.placenta.2017.06.016_bib11","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.placenta.2013.11.015","article-title":"Association between first-trimester placental volume and birth weight","volume":"35","author":"Effendi","year":"2014","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2017.06.016_bib12","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/j.placenta.2013.05.003","article-title":"2D-Ultrasound and endocrinologic evaluation of placentation in early pregnancy and its relationship to fetal birthweight in normal pregnancies and pre-eclampsia","volume":"34","author":"Suri","year":"2013","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2017.06.016_bib13","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.placenta.2011.01.010","article-title":"Placental volume and vascular flow assessed by 3D power Doppler and adverse pregnancy outcomes","volume":"32","author":"Odibo","year":"2011","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2017.06.016_bib14","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1159\/000324318","article-title":"Placental volume at 11-13 weeks' gestation in the prediction of birth weight percentile","volume":"30","author":"Plasencia","year":"2011","journal-title":"Fetal Diagn. Ther."},{"key":"10.1016\/j.placenta.2017.06.016_bib15","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1002\/uog.7308","article-title":"Placental size and the prediction of severe early-onset intrauterine growth restriction in women with low pregnancy-associated plasma protein-A","volume":"34","author":"Proctor","year":"2009","journal-title":"Ultrasound Obstet. Gynecol."},{"key":"10.1016\/j.placenta.2017.06.016_bib16","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.placenta.2010.11.001","article-title":"Three-dimensional ultrasound evaluation of the placenta","volume":"32","author":"Hata","year":"2011","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2017.06.016_bib17","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1002\/uog.14819","article-title":"Prediction and prevention of early-onset pre-eclampsia: impact of aspirin after first-trimester screening","volume":"46","author":"Park","year":"2015","journal-title":"Ultrasound Obstet. Gynecol."},{"key":"10.1016\/j.placenta.2017.06.016_bib18","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1097\/AOG.0b013e3181e9322a","article-title":"Prevention of preeclampsia and intrauterine growth restriction with aspirin started in early pregnancy: a meta-analysis","volume":"116","author":"Bujold","year":"2010","journal-title":"Obstetrics Gynecol."},{"key":"10.1016\/j.placenta.2017.06.016_bib19","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1002\/uog.12421","article-title":"Prevention of perinatal death and adverse perinatal outcome using low-dose aspirin: a meta-analysis","volume":"41","author":"Roberge","year":"2013","journal-title":"Ultrasound Obstetrics Gynecol. Official J. Int. Soc. Ultrasound Obstetrics Gynecol."},{"key":"10.1016\/j.placenta.2017.06.016_bib20","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1111\/j.1471-0528.2006.00882.x","article-title":"Morphometric placental villous and vascular abnormalities in early- and late-onset pre-eclampsia with and without fetal growth restriction","volume":"113","author":"Egbor","year":"2006","journal-title":"BJOG"},{"key":"10.1016\/j.placenta.2017.06.016_bib21","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1053\/plac.1999.0466","article-title":"Sonographically thick placenta: a marker for increased perinatal risk\u2013a prospective cross-sectional study","volume":"21","author":"Elchalal","year":"2000","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2017.06.016_bib22","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1002\/uog.12386","article-title":"Placental hyperinflation and the risk of adverse perinatal outcome","volume":"42","author":"Porat","year":"2013","journal-title":"Ultrasound Obstet. Gynecol."},{"key":"10.1016\/j.placenta.2017.06.016_bib23","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.7863\/jum.2010.29.8.1203","article-title":"Novel 3-dimensional placental measurements in early pregnancy as predictors of adverse pregnancy outcomes","volume":"29","author":"Schwartz","year":"2010","journal-title":"J.\u00a0Ultrasound Med."},{"key":"10.1016\/j.placenta.2017.06.016_bib24","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1053\/plac.2001.0684","article-title":"Three-dimensional ultrasound measurement of the placental volume in early pregnancy: method and correlation with biochemical placenta parameters","volume":"22","author":"Metzenbauer","year":"2001","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2017.06.016_bib25","doi-asserted-by":"crossref","first-page":"E35","DOI":"10.1542\/peds.108.2.e35","article-title":"Fetal\/Infant Health Study Group of the Canadian Perinatal Surveillance S: a new and improved population-based Canadian reference for birth weight for gestational age","volume":"108","author":"Kramer","year":"2001","journal-title":"Pediatrics"},{"issue":"253","key":"10.1016\/j.placenta.2017.06.016_bib26","first-page":"e1","article-title":"First-trimester placental ultrasound and maternal serum markers as predictors of small-for-gestational-age infants","volume":"211","author":"Schwartz","year":"2014","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.placenta.2017.06.016_bib27","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.placenta.2016.02.005","article-title":"Ultrasound and endocrinological markers of first trimester placentation and subsequent fetal size","volume":"40","author":"David","year":"2016","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2017.06.016_bib28","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1016\/S0002-9378(96)70103-5","article-title":"Intrauterine growth restriction with absent end-diastolic flow velocity in the umbilical artery is associated with maldevelopment of the placental terminal villous tree","volume":"175","author":"Krebs","year":"1996","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.placenta.2017.06.016_bib29","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1159\/000357842","article-title":"Maternal serum placental growth factor (PlGF) isoforms 1 and 2 at 11-13 weeks' gestation in normal and pathological pregnancies","volume":"36","author":"Nucci","year":"2014","journal-title":"Fetal Diagn Ther."},{"key":"10.1016\/j.placenta.2017.06.016_bib30","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1002\/pd.2143","article-title":"Maternal serum placental growth factor (PlGF) in small for gestational age pregnancy at 11(+0) to 13(+6) weeks of gestation","volume":"28","author":"Poon","year":"2008","journal-title":"Prenat. Diagn"},{"key":"10.1016\/j.placenta.2017.06.016_bib31","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1002\/pd.2525","article-title":"First-trimester placental growth factor as a marker for hypertensive disorders and SGA","volume":"30","author":"Cowans","year":"2010","journal-title":"Prenat. Diagn."},{"issue":"595","key":"10.1016\/j.placenta.2017.06.016_bib32","first-page":"e1","article-title":"Placental weight and birthweight: does the association differ between pregnancies with and without preeclampsia?","volume":"201","author":"Eskild","year":"2009","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.placenta.2017.06.016_bib33","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1161\/HYPERTENSIONAHA.111.182170","article-title":"Transcriptionally active syncytial aggregates in the maternal circulation may contribute to circulating soluble fms-like tyrosine kinase 1 in preeclampsia","volume":"59","author":"Rajakumar","year":"2012","journal-title":"Hypertension"},{"key":"10.1016\/j.placenta.2017.06.016_bib34","doi-asserted-by":"crossref","first-page":"2486","DOI":"10.1111\/j.1538-7836.2011.04526.x","article-title":"Heparin promotes soluble VEGF receptor expression in human placental villi to impair endothelial VEGF signaling","volume":"9","author":"Drewlo","year":"2011","journal-title":"J.\u00a0Thromb. Haemost."},{"key":"10.1016\/j.placenta.2017.06.016_bib35","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1056\/NEJMoa1414838","article-title":"Predictive value of the sFlt-1:PlGF ratio in women with suspected preeclampsia","volume":"374","author":"Zeisler","year":"2016","journal-title":"N.\u00a0Engl. J. Med."},{"key":"10.1016\/j.placenta.2017.06.016_bib36","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1038\/jp.2013.176","article-title":"Placental pathology, first-trimester biomarkers and adverse pregnancy outcomes","volume":"34","author":"Odibo","year":"2014","journal-title":"J.\u00a0Perinatol."},{"key":"10.1016\/j.placenta.2017.06.016_bib37","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1503\/cmaj.070430","article-title":"Use of uterine artery Doppler ultrasonography to predict pre-eclampsia and intrauterine growth restriction: a systematic review and bivariable meta-analysis","volume":"178","author":"Cnossen","year":"2008","journal-title":"CMAJ"},{"key":"10.1016\/j.placenta.2017.06.016_bib38","doi-asserted-by":"crossref","first-page":"199","DOI":"10.2217\/whe.15.95","article-title":"The use of ultrasound and other markers for early detection of preeclampsia","volume":"12","author":"O'Gorman","year":"2016","journal-title":"Womens Health (Lond Engl)"},{"key":"10.1016\/j.placenta.2017.06.016_bib39","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1002\/pd.4519","article-title":"First trimester screening for early and late preeclampsia based on maternal characteristics, biophysical parameters, and angiogenic factors","volume":"35","author":"Crovetto","year":"2015","journal-title":"Prenat. Diagn"},{"issue":"2","key":"10.1016\/j.placenta.2017.06.016_bib40","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1002\/uog.15982","article-title":"Validation of a first-trimester screening model for pre-eclampsia in an unselected population","volume":"49","author":"Scazzocchio","year":"2016","journal-title":"Ultrasound Obstetrics Gynecol. Official J. Int. Soc. Ultrasound Obstetrics Gynecol."}],"container-title":["Placenta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400417303120?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400417303120?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T17:56:27Z","timestamp":1758909387000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0143400417303120"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9]]},"references-count":40,"alternative-id":["S0143400417303120"],"URL":"https:\/\/doi.org\/10.1016\/j.placenta.2017.06.016","relation":{},"ISSN":["0143-4004"],"issn-type":[{"value":"0143-4004","type":"print"}],"subject":[],"published":{"date-parts":[[2017,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"First-trimester placental thickness and the risk of preeclampsia or SGA","name":"articletitle","label":"Article Title"},{"value":"Placenta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.placenta.2017.06.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}