{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T11:31:13Z","timestamp":1785238273914,"version":"3.55.0"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,7,1]],"date-time":"2018-07-01T00:00:00Z","timestamp":1530403200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,7,1]],"date-time":"2018-07-01T00:00:00Z","timestamp":1530403200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81741015"],"award-info":[{"award-number":["81741015"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Placenta"],"published-print":{"date-parts":[[2018,7]]},"DOI":"10.1016\/j.placenta.2018.05.012","type":"journal-article","created":{"date-parts":[[2018,5,29]],"date-time":"2018-05-29T12:44:01Z","timestamp":1527597841000},"page":"38-44","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"special_numbering":"C","title":["Estrogen-related receptor \u03b3 regulates expression of 17\u03b2-hydroxysteroid dehydrogenase type 1 in fetal growth restriction"],"prefix":"10.1016","volume":"67","author":[{"given":"Hui","family":"Zhu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linhuan","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiming","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiyong","family":"Zou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7354-0767","authenticated-orcid":false,"given":"Yanmin","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.placenta.2018.05.012_bib1","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1111\/j.0001-6349.2004.00602.x","article-title":"Restricted fetal growth in sudden intrauterine unexplained death","volume":"83","author":"Froen","year":"2004","journal-title":"Acta Obstet. Gynecol. Scand."},{"key":"10.1016\/j.placenta.2018.05.012_bib2","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1542\/peds.2005-1368","article-title":"Growth in the neonatal intensive care unit influences neurodevelopment and growth outcomes of extremely low birth weight infants","volume":"117","author":"Ehrenkranz","year":"2006","journal-title":"Pediatrics"},{"key":"10.1016\/j.placenta.2018.05.012_bib3","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1111\/j.1471-0528.2008.01827.x","article-title":"Cerebral palsy and restricted growth status at birth: population-based case-control study","volume":"115","author":"Jacobsson","year":"2008","journal-title":"BJOG"},{"key":"10.1016\/j.placenta.2018.05.012_bib4","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.ejogrb.2010.11.017","article-title":"Placental pathology in fetal growth restriction","volume":"155","author":"Vedmedovska","year":"2011","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"key":"10.1016\/j.placenta.2018.05.012_bib5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1600-0897.2012.01132.x","article-title":"Changes in the maternal cytokine profile in pregnancies complicated by fetal growth restriction","volume":"68","author":"Mullins","year":"2012","journal-title":"Am. J. Reprod. Immunol."},{"key":"10.1016\/j.placenta.2018.05.012_bib6","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1055\/s-0031-1275515","article-title":"Placental dysfunction and fetal programming: the importance of placental size, shape, histopathology, and molecular composition","volume":"29","author":"Longtine","year":"2011","journal-title":"Semin. Reprod. Med."},{"key":"10.1016\/j.placenta.2018.05.012_bib7","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1038\/331091a0","article-title":"Identification of a new class of steroid hormone receptors","volume":"331","author":"Gigu\u00e8re","year":"1988","journal-title":"Nature"},{"key":"10.1016\/j.placenta.2018.05.012_bib8","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1016\/j.placenta.2012.06.002","article-title":"Estrogen-related receptor gamma modulates energy metabolism target genes in human trophoblast","volume":"33","author":"Poidatz","year":"2012","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2018.05.012_bib9","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1093\/jb\/mvp049","article-title":"Placenta expressing the greatest quantity of bisphenol A receptor ERR{gamma} among the human reproductive tissues: predominant expression of type-1 ERRgamma isoform","volume":"146","author":"Takeda","year":"2009","journal-title":"J. Biochem."},{"key":"10.1016\/j.placenta.2018.05.012_bib10","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1210\/me.2011-1012","article-title":"Estrogen-related receptor {gamma} (ERR{gamma}) mediates oxygen-dependent induction of aromatase (CYP19) gene expression during human trophoblast differentiation","volume":"25","author":"Kumar","year":"2011","journal-title":"Mol. Endocrinol."},{"key":"10.1016\/j.placenta.2018.05.012_bib11","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1210\/me.2014-1003","article-title":"Estrogen-related receptor gamma serves a role in blood pressure homeostasis during pregnancy","volume":"28","author":"Luo","year":"2014","journal-title":"Mol. Endocrinol."},{"key":"10.1016\/j.placenta.2018.05.012_bib12","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.mce.2005.12.007","article-title":"Structure and function of human 17beta-hydroxysteroid dehydrogenases","volume":"248","author":"Lukacik","year":"2006","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.placenta.2018.05.012_bib13","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.jsbmb.2014.09.017","article-title":"Reductive 17beta-hydroxysteroid dehydrogenases which synthesize estradiol and inactivate dihydrotestosterone constitute major and concerted players in ER+ breast cancer cells","volume":"150","author":"Zhang","year":"2015","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.placenta.2018.05.012_bib14","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.mce.2016.11.030","article-title":"High mRNA levels of 17\u03b2-hydroxysteroid dehydrogenase type 1 correlate with poor prognosis in endometrial cancer","volume":"442","author":"Cornel","year":"2017","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.placenta.2018.05.012_bib15","doi-asserted-by":"crossref","first-page":"2250","DOI":"10.3109\/14767058.2014.984289","article-title":"Evidence for association of the rs605059 polymorphism of HSD17B1 gene with recurrent spontaneous abortions","volume":"28","author":"Ntostis","year":"2015","journal-title":"J. Matern. Fetal Neonatal Med."},{"key":"10.1016\/j.placenta.2018.05.012_bib16","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1210\/me.2008-0371","article-title":"Estrogen receptor alpha (ERalpha) mediates stimulatory effects of estrogen on aromatase (CYP19) gene expression in human placenta","volume":"23","author":"Kumar","year":"2009","journal-title":"Mol. Endocrinol."},{"key":"10.1016\/j.placenta.2018.05.012_bib17","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1210\/me.2013-1038","article-title":"Estrogen-related receptor \u03b3 (ERR\u03b3) regulates oxygen-dependent expression of voltage-gated potassium (K+) channels and tissue kallikrein during human trophoblast differentiation","volume":"27","author":"Luo","year":"2013","journal-title":"Mol. Endocrinol."},{"key":"10.1016\/j.placenta.2018.05.012_bib18","first-page":"97","article-title":"Chinese neonatal birth weight curve for different gestational age","volume":"53","author":"Zhu","year":"2015","journal-title":"Chin. J. Pediatr"},{"key":"10.1016\/j.placenta.2018.05.012_bib19","doi-asserted-by":"crossref","first-page":"813","DOI":"10.7863\/jum.1999.18.12.813","article-title":"Estimation of fetal growth mean: value from multiple formulas","volume":"18","author":"Pinette","year":"1999","journal-title":"J. Ultrasound Med."},{"key":"10.1016\/j.placenta.2018.05.012_bib20","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.placenta.2018.05.012_bib21","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/1477-7827-5-6","article-title":"Control of human trophoblast function","volume":"5","author":"Lunghi","year":"2007","journal-title":"Reprod. Biol. Endocrinol."},{"key":"10.1016\/j.placenta.2018.05.012_bib22","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/0028-2243(84)90047-9","article-title":"The making of placental bed","volume":"18","author":"Robertson","year":"1984","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"key":"10.1016\/j.placenta.2018.05.012_bib23","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/S0140-6736(10)60279-6","article-title":"Preeclampsia","volume":"376","author":"Steegers","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.placenta.2018.05.012_bib24","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.fertnstert.2015.05.005","article-title":"Involvement of estrogen-related receptor-\u03b3 and mitochondrial content in intrauterine growth restriction and preeclampsia","volume":"104","author":"Poidat","year":"2015","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.placenta.2018.05.012_bib25","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1210\/er.2008-0017","article-title":"Transcriptional control of energy homeostasis by the estrogen-related receptors","volume":"29","author":"Giguere","year":"2008","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.placenta.2018.05.012_bib26","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.cmet.2011.01.019","article-title":"Exercise and PGC-1alpha-independent synchronization of type I muscle metabolism and vasculature by ERRgamma","volume":"13","author":"Narkar","year":"2011","journal-title":"Cell Metabol."},{"key":"10.1016\/j.placenta.2018.05.012_bib27","doi-asserted-by":"crossref","first-page":"e213","DOI":"10.1038\/emm.2015.115","article-title":"Estrogen-related receptor \u03b3 is upregulated in liver cancer and its inhibition suppresses liver cancer cell proliferation via induction of p21 and p27","volume":"48","author":"Kim","year":"2016","journal-title":"Exp. Mol. Med."},{"key":"10.1016\/j.placenta.2018.05.012_bib28","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jsbmb.2010.09.002","article-title":"Estrogen-related receptor \u03b3 modulates cell proliferation and estrogen signaling in breast cancer","volume":"123","author":"Ijichi","year":"2011","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.placenta.2018.05.012_bib29","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1186\/s13046-015-0150-9","article-title":"ERR\u03b3 target genes are poor prognostic factors in Tamoxifen-treated breast cancer","volume":"34","author":"Madhavan","year":"2015","journal-title":"J. Exp. Clin. Canc. Res."},{"key":"10.1016\/j.placenta.2018.05.012_bib30","doi-asserted-by":"crossref","DOI":"10.1139\/y02-006","article-title":"Human placental trophoblast as an in vitro model for tumor progression","volume":"80","author":"Lala","year":"2002","journal-title":"Can. J. Physiol. Pharmacol."},{"key":"10.1016\/j.placenta.2018.05.012_bib31","doi-asserted-by":"crossref","DOI":"10.1186\/bcr3207","article-title":"17beta-hydroxysteroid dehydrogenase type 1 modulates breast cancer protein profile and impacts cell migration","volume":"14","author":"Aka","year":"2012","journal-title":"Breast Cancer Res."},{"key":"10.1016\/j.placenta.2018.05.012_bib32","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1186\/1479-5876-11-167","article-title":"Intratumoral localization and activity of 17\u03b2 -hydroxysteroid dehydrogenase type 1 in non-small cell lung cancer: a potent prognostic factor","volume":"11","author":"Verma","year":"2013","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.placenta.2018.05.012_bib33","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.1210\/mend.14.10.0539","article-title":"Hypoxia prevents induction of aromatase expression in human trophoblast cells in culture: potential inhibitory role of the hypoxia-inducible transcription factor Mash-2 (mammalian achaete-scute homologous protein-2)","volume":"14","author":"Jiang","year":"2000","journal-title":"Mol. Endocrinol."},{"key":"10.1016\/j.placenta.2018.05.012_bib34","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1113\/jphysiol.2005.086439","article-title":"Uterine blood flow responses to ICI 182 780 in ovariectomized oestradiol-17beta-treated, intact follicular and pregnant sheep","volume":"565","author":"Magness","year":"2005","journal-title":"J. Physiol."},{"key":"10.1016\/j.placenta.2018.05.012_bib35","doi-asserted-by":"crossref","first-page":"4341","DOI":"10.1210\/jc.2001-010588","article-title":"17beta-estradiol up-regulates vascular endothelial growth factor receptor-2 expression in human myometrial microvascular endothelial cells: role of estrogen receptor-alpha and -beta","volume":"87","author":"Gargett","year":"2002","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.placenta.2018.05.012_bib36","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.bbrc.2015.03.055","article-title":"Retinal hypoxia induces vascular endothelial growth factor through induction of estrogen-related receptor \u03b3","volume":"460","author":"Do","year":"2015","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.placenta.2018.05.012_bib37","doi-asserted-by":"crossref","first-page":"2384","DOI":"10.1161\/ATVBAHA.115.306102","article-title":"Estrogen-related receptor \u03b3 plays a key role in vascular calcification through the upregulation of BMP2 expression","volume":"35","author":"Kim","year":"2015","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.placenta.2018.05.012_bib38","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1038\/nrd1551","article-title":"Principles for modulation of the nuclear receptor superfamily","volume":"3","author":"Gronemeyer","year":"2004","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.placenta.2018.05.012_bib39","doi-asserted-by":"crossref","first-page":"37773","DOI":"10.1074\/jbc.M608410200","article-title":"X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation","volume":"281","author":"Wang","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.placenta.2018.05.012_bib40","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1038\/nrc3396","article-title":"Oestrogen-related receptors in breast cancer: control of cellular metabolism and beyond","volume":"13","author":"Deblois","year":"2013","journal-title":"Nat. Rev. Canc."}],"container-title":["Placenta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400418302704?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400418302704?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T17:58:00Z","timestamp":1758909480000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0143400418302704"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7]]},"references-count":40,"alternative-id":["S0143400418302704"],"URL":"https:\/\/doi.org\/10.1016\/j.placenta.2018.05.012","relation":{},"ISSN":["0143-4004"],"issn-type":[{"value":"0143-4004","type":"print"}],"subject":[],"published":{"date-parts":[[2018,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Estrogen-related receptor \u03b3 regulates expression of 17\u03b2-hydroxysteroid dehydrogenase type 1 in fetal growth restriction","name":"articletitle","label":"Article Title"},{"value":"Placenta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.placenta.2018.05.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}