{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T02:31:24Z","timestamp":1777775484301,"version":"3.51.4"},"reference-count":27,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1159261"],"award-info":[{"award-number":["1159261"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1136418"],"award-info":[{"award-number":["1136418"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1146128"],"award-info":[{"award-number":["1146128"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1150828"],"award-info":[{"award-number":["1150828"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Placenta"],"published-print":{"date-parts":[[2020,6]]},"DOI":"10.1016\/j.placenta.2020.04.012","type":"journal-article","created":{"date-parts":[[2020,4,27]],"date-time":"2020-04-27T12:50:00Z","timestamp":1587991800000},"page":"53-61","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Aurora kinase mRNA expression is reduced with increasing gestational age and in severe early onset fetal growth restriction"],"prefix":"10.1016","volume":"95","author":[{"given":"Sally","family":"Beard","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natasha","family":"Pritchard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalie","family":"Binder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen","family":"Schindler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natasha","family":"De Alwis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tu'uhevaha J.","family":"Kaitu'u-Lino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen","family":"Tong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalie J.","family":"Hannan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"9249","key":"10.1016\/j.placenta.2020.04.012_bib1","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0140-6736(00)03577-7","article-title":"Pathogenesis and genetics of pre-eclampsia","volume":"357","author":"Roberts","year":"2001","journal-title":"Lancet (London, England)"},{"key":"10.1016\/j.placenta.2020.04.012_bib2","doi-asserted-by":"crossref","first-page":"67","DOI":"10.4137\/CMPed.S40070","article-title":"Intrauterine growth restriction: antenatal and postnatal aspects","volume":"10","author":"Sharma","year":"2016","journal-title":"Clin. Med. Insights Pediatr."},{"issue":"9608","key":"10.1016\/j.placenta.2020.04.012_bib3","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/S0140-6736(08)60136-1","article-title":"Preterm Birth 3: an overview of mortality and sequelae of preterm birth from infancy to adulthood","volume":"371","author":"Saigal","year":"2008","journal-title":"Lancet"},{"issue":"4","key":"10.1016\/j.placenta.2020.04.012_bib4","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.ajog.2017.06.015","article-title":"Evidence that fetal death is associated with placental aging","volume":"217","author":"Maiti","year":"2017","journal-title":"Am. J. Obstet. Gynecol."},{"issue":"2, Supplement","key":"10.1016\/j.placenta.2020.04.012_bib5","doi-asserted-by":"crossref","first-page":"S762","DOI":"10.1016\/j.ajog.2017.11.567","article-title":"Is there a role for placental senescence in the genesis of obstetric complications and fetal growth restriction?","volume":"218","author":"Sultana","year":"2018","journal-title":"Am. J. Obstet. Gynecol."},{"issue":"2","key":"10.1016\/j.placenta.2020.04.012_bib6","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.cell.2007.07.003","article-title":"Cellular senescence in cancer and aging","volume":"130","author":"Collado","year":"2007","journal-title":"Cell"},{"issue":"22","key":"10.1016\/j.placenta.2020.04.012_bib7","doi-asserted-by":"crossref","first-page":"3569","DOI":"10.1016\/j.febslet.2011.10.022","article-title":"Down-regulation of Aurora B kinase induces cellular senescence in human fibroblasts and endothelial cells through a p53-dependent pathway","volume":"585","author":"Kim","year":"2011","journal-title":"FEBS (Fed. Eur. Biochem. Soc.) Lett."},{"issue":"5","key":"10.1016\/j.placenta.2020.04.012_bib8","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/S0092-8674(03)00642-1","article-title":"Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells","volume":"114","author":"Hirota","year":"2003","journal-title":"Cell"},{"issue":"21","key":"10.1016\/j.placenta.2020.04.012_bib9","doi-asserted-by":"crossref","first-page":"3458","DOI":"10.1016\/j.cub.2018.08.052","article-title":"Genetic interactions between the aurora kinases reveal new requirements for AURKB and AURKC during oocyte meiosis","volume":"28","author":"Nguyen","year":"2018","journal-title":"Curr. Biol. : CB (Curr. Biol.)"},{"key":"10.1016\/j.placenta.2020.04.012_bib10","doi-asserted-by":"crossref","first-page":"50","DOI":"10.3389\/fcell.2015.00050","article-title":"Functions of Aurora kinase C in meiosis and cancer","volume":"3","author":"Quartuccio","year":"2015","journal-title":"Front. Cell. Develop. Biol."},{"issue":"1","key":"10.1016\/j.placenta.2020.04.012_bib11","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.bbrc.2004.12.168","article-title":"Cloning and characterization of a novel human Aurora C splicing variant","volume":"328","author":"Yan","year":"2005","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"33","key":"10.1016\/j.placenta.2020.04.012_bib12","doi-asserted-by":"crossref","first-page":"E2215","DOI":"10.1073\/pnas.1120517109","article-title":"Maternally recruited Aurora C kinase is more stable than Aurora B to support mouse oocyte maturation and early development","volume":"109","author":"Schindler","year":"2012","journal-title":"Proc. Natl. Acad. Sci. Unit. States Am."},{"issue":"10\u201312","key":"10.1016\/j.placenta.2020.04.012_bib13","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1016\/j.bbagrm.2010.09.004","article-title":"Aurora kinase inhibitors as anticancer molecules","volume":"1799","author":"Katayama","year":"2010","journal-title":"Biochim. Biophys. Acta"},{"issue":"14","key":"10.1016\/j.placenta.2020.04.012_bib14","doi-asserted-by":"crossref","first-page":"23937","DOI":"10.18632\/oncotarget.14893","article-title":"Aurora kinases: novel therapy targets in cancers","volume":"8","author":"Tang","year":"2017","journal-title":"Oncotarget"},{"issue":"2","key":"10.1016\/j.placenta.2020.04.012_bib15","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1002\/path.2934","article-title":"Aberrantly expressed AURKC enhances the transformation and tumourigenicity of epithelial cells","volume":"225","author":"Tsou","year":"2011","journal-title":"J. Pathol."},{"issue":"7","key":"10.1016\/j.placenta.2020.04.012_bib16","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1111\/j.1440-1827.2006.01974.x","article-title":"Expression of serine threonine kinase 15 is associated with poor differentiation in lung squamous cell carcinoma and adenocarcinoma","volume":"56","author":"Xu","year":"2006","journal-title":"Pathol. Int."},{"issue":"5\u20136","key":"10.1016\/j.placenta.2020.04.012_bib17","doi-asserted-by":"crossref","first-page":"241","DOI":"10.3727\/096504013X13589503482978","article-title":"Gene amplification and overexpression of Aurora-C in breast and prostate cancer cell lines","volume":"20","author":"Zekri","year":"2012","journal-title":"Oncol. Res."},{"key":"10.1016\/j.placenta.2020.04.012_bib18","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1038\/ncomms2074","article-title":"Enhanced HSP70 lysine methylation promotes proliferation of cancer cells through activation of Aurora kinase B","volume":"3","author":"Cho","year":"2012","journal-title":"Nat. Commun."},{"key":"10.1016\/j.placenta.2020.04.012_bib19","doi-asserted-by":"crossref","first-page":"2632637","DOI":"10.1155\/2018\/2632637","article-title":"Clinical presentation of preeclampsia and the diagnostic value of proteins and their methylation products as biomarkers in pregnant women with preeclampsia and their newborns","volume":"2018","author":"Portelli","year":"2018","journal-title":"J. Pregnancy"},{"issue":"5","key":"10.1016\/j.placenta.2020.04.012_bib20","first-page":"1122","article-title":"American college of O, gynecologists, task force on hypertension in P. Hypertension in pregnancy. Report of the American college of obstetricians and gynecologists' task force on hypertension in pregnancy","volume":"122","year":"2013","journal-title":"Obstet. Gynecol."},{"issue":"5","key":"10.1016\/j.placenta.2020.04.012_bib21","doi-asserted-by":"crossref","first-page":"291","DOI":"10.5694\/mja11.11331","article-title":"Australian national birthweight percentiles by sex and gestational age, 1998-2007","volume":"197","author":"Dobbins","year":"2012","journal-title":"Med. J. Aust."},{"issue":"1","key":"10.1016\/j.placenta.2020.04.012_bib22","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.placenta.2013.11.005","article-title":"Optimising sample collection for placental research","volume":"35","author":"Burton","year":"2014","journal-title":"Placenta"},{"issue":"11","key":"10.1016\/j.placenta.2020.04.012_bib23","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0078487","article-title":"Circulating MicroRNAs in maternal blood as potential biomarkers for fetal hypoxia in-utero","volume":"8","author":"Whitehead","year":"2013","journal-title":"PloS One"},{"key":"10.1016\/j.placenta.2020.04.012_bib24","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.freeradbiomed.2016.12.031","article-title":"Oxidative stress induces mitotic arrest by inhibiting Aurora A-involved mitotic spindle formation","volume":"103","author":"Wang","year":"2017","journal-title":"Free Radic. Biol. Med."},{"issue":"8","key":"10.1016\/j.placenta.2020.04.012_bib25","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1097\/CAD.0000000000000523","article-title":"Reactive oxygen species generation and increase in mitochondrial copy number: new insight into the potential mechanism of cytotoxicity induced by aurora kinase inhibitor, AZD1152-HQPA","volume":"28","author":"Zekri","year":"2017","journal-title":"Anti Canc. Drugs"},{"key":"10.1016\/j.placenta.2020.04.012_bib26","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/bs.pmbts.2016.12.006","article-title":"Role of exosomes in placental homeostasis and pregnancy disorders","volume":"145","author":"Salomon","year":"2017","journal-title":"Prog. Mol. Biol. Transl. Sci."},{"issue":"4","key":"10.1016\/j.placenta.2020.04.012_bib27","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.placenta.2012.11.010","article-title":"The placental factor in early- and late-onset normotensive fetal growth restriction","volume":"34","author":"Kovo","year":"2013","journal-title":"Placenta"}],"container-title":["Placenta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400420301156?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400420301156?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T18:10:48Z","timestamp":1777486248000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0143400420301156"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6]]},"references-count":27,"alternative-id":["S0143400420301156"],"URL":"https:\/\/doi.org\/10.1016\/j.placenta.2020.04.012","relation":{},"ISSN":["0143-4004"],"issn-type":[{"value":"0143-4004","type":"print"}],"subject":[],"published":{"date-parts":[[2020,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Aurora kinase mRNA expression is reduced with increasing gestational age and in severe early onset fetal growth restriction","name":"articletitle","label":"Article Title"},{"value":"Placenta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.placenta.2020.04.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}