{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T13:36:33Z","timestamp":1791466593055,"version":"4.3.4"},"reference-count":64,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,5,20]],"date-time":"2021-05-20T00:00:00Z","timestamp":1621468800000},"content-version":"am","delay-in-days":323,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000199","name":"U.S. Department of Agriculture","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000199","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Placenta"],"published-print":{"date-parts":[[2020,7]]},"DOI":"10.1016\/j.placenta.2020.05.002","type":"journal-article","created":{"date-parts":[[2020,5,7]],"date-time":"2020-05-07T11:42:45Z","timestamp":1588851765000},"page":"1-9","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":27,"special_numbering":"C","title":["Adaptive responses to maternal nutrient restriction alter placental transport in ewes"],"prefix":"10.1016","volume":"96","author":[{"given":"Ashley K.","family":"Edwards","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sorin M.","family":"McKnight","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katharine","family":"Askelson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason R.","family":"McKnight","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathrin A.","family":"Dunlap","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Carey","family":"Satterfield","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"Pt 1","key":"10.1016\/j.placenta.2020.05.002_bib1","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1113\/jphysiol.2004.082032","article-title":"Investigating the causes of low birth weight in contrasting ovine paradigms","volume":"565","author":"Wallace","year":"2005","journal-title":"J. Physiol."},{"issue":"9","key":"10.1016\/j.placenta.2020.05.002_bib2","doi-asserted-by":"crossref","first-page":"2316","DOI":"10.2527\/jas.2006-156","article-title":"Board-invited review: intrauterine growth retardation: implications for the animal sciences","volume":"84","author":"Wu","year":"2006","journal-title":"J. Anim. Sci."},{"issue":"5","key":"10.1016\/j.placenta.2020.05.002_bib3","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1111\/j.1365-2796.2007.01809.x","article-title":"The origins of the developmental origins theory","volume":"261","author":"Barker","year":"2007","journal-title":"J. Intern. Med."},{"issue":"1","key":"10.1016\/j.placenta.2020.05.002_bib4","doi-asserted-by":"crossref","first-page":"R12","DOI":"10.1152\/ajpregu.00687.2003","article-title":"Programming of adult cardiovascular function after early maternal undernutrition in sheep","volume":"287","author":"Gopalakrishnan","year":"2004","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"issue":"3","key":"10.1016\/j.placenta.2020.05.002_bib5","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1038\/sj.ki.5002276","article-title":"Hypertension and impaired renal function accompany juvenile obesity: the effect of prenatal diet","volume":"72","author":"Williams","year":"2007","journal-title":"Kidney Int."},{"key":"10.1016\/j.placenta.2020.05.002_bib6","first-page":"411","article-title":"Flock differences in the impact of maternal dietary restriction on offspring growth and glucose tolerance in female offspring","volume":"64","author":"Burt","year":"2007","journal-title":"Soc. Reprod. Fertil. Suppl."},{"issue":"4","key":"10.1016\/j.placenta.2020.05.002_bib7","doi-asserted-by":"crossref","first-page":"R947","DOI":"10.1152\/ajpregu.00120.2005","article-title":"Programming of glucose-insulin metabolism in adult sheep after maternal undernutrition","volume":"289","author":"Gardner","year":"2005","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"issue":"3","key":"10.1016\/j.placenta.2020.05.002_bib8","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1095\/biolreprod.104.029645","article-title":"Maternal nutrient restriction reduces concentrations of amino acids and polyamines in ovine maternal and fetal plasma and fetal fluids","volume":"71","author":"Kwon","year":"2004","journal-title":"Biol. Reprod."},{"issue":"2","key":"10.1016\/j.placenta.2020.05.002_bib9","doi-asserted-by":"crossref","first-page":"251","DOI":"10.3945\/jn.109.114678","article-title":"Sildenafil citrate treatment enhances amino acid availability in the conceptus and fetal growth in an ovine model of intrauterine growth restriction","volume":"140","author":"Satterfield","year":"2010","journal-title":"J. Nutr."},{"issue":"1","key":"10.1016\/j.placenta.2020.05.002_bib10","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1095\/biolreprod.102.012120","article-title":"Maternal undernutrition from early- to mid-gestation leads to growth retardation, cardiac ventricular hypertrophy, and increased liver weight in the fetal sheep","volume":"69","author":"Vonnahme","year":"2003","journal-title":"Biol. Reprod."},{"issue":"6","key":"10.1016\/j.placenta.2020.05.002_bib11","doi-asserted-by":"crossref","first-page":"1826","DOI":"10.2527\/2004.8261826x","article-title":"The effect of dietary restriction, pregnancy, and fetal type in different Ewe types on fetal weight, maternal body weight, and visceral organ mass in ewes","volume":"82","author":"Scheaffer","year":"2004","journal-title":"J. Anim. Sci."},{"issue":"6","key":"10.1016\/j.placenta.2020.05.002_bib12","doi-asserted-by":"crossref","first-page":"1950","DOI":"10.2527\/jas.2008-1672","article-title":"Effects of early gestational undernutrition on fetal growth, organ development, and placentomal composition in the bovine","volume":"87","author":"Long","year":"2009","journal-title":"J. Anim. Sci."},{"issue":"12","key":"10.1016\/j.placenta.2020.05.002_bib13","doi-asserted-by":"crossref","first-page":"3451","DOI":"10.2527\/jas.2006-132","article-title":"Placentomal differentiation may compensate for maternal nutrient restriction in ewes adapted to harsh range conditions","volume":"84","author":"Vonnahme","year":"2006","journal-title":"J. Anim. Sci."},{"issue":"4","key":"10.1016\/j.placenta.2020.05.002_bib14","doi-asserted-by":"crossref","first-page":"820","DOI":"10.2527\/jas.2007-0624","article-title":"Baggs ewes adapt to maternal undernutrition and maintain conceptus growth by maintaining fetal plasma concentrations of amino acids","volume":"86","author":"Jobgen","year":"2008","journal-title":"J. Anim. Sci."},{"issue":"3 Pt 2","key":"10.1016\/j.placenta.2020.05.002_bib15","first-page":"R427","article-title":"Effect of restriction of placental growth on umbilical and uterine blood flows","volume":"250","author":"Owens","year":"1986","journal-title":"Am. J. Physiol."},{"issue":"Suppl 1","key":"10.1016\/j.placenta.2020.05.002_bib16","doi-asserted-by":"crossref","first-page":"S55","DOI":"10.1016\/S0301-2115(03)00173-8","article-title":"Uterine blood flow--a determinant of fetal growth","volume":"110","author":"Lang","year":"2003","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"issue":"Pt 3","key":"10.1016\/j.placenta.2020.05.002_bib17","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1113\/jphysiol.2009.181214","article-title":"Adaptations in placental phenotype support fetal growth during undernutrition of pregnant mice","volume":"588","author":"Coan","year":"2010","journal-title":"J. Physiol."},{"issue":"1 Pt 1","key":"10.1016\/j.placenta.2020.05.002_bib18","doi-asserted-by":"crossref","first-page":"C295","DOI":"10.1152\/ajpcell.1996.271.1.C295","article-title":"Effect of low-protein diet-induced intrauterine growth retardation on rat placental amino acid transport","volume":"271","author":"Malandro","year":"1996","journal-title":"Am. J. Physiol."},{"issue":"Pt 3","key":"10.1016\/j.placenta.2020.05.002_bib19","first-page":"935","article-title":"Down-regulation of placental transport of amino acids precedes the development of intrauterine growth restriction in rats fed a low protein diet","volume":"576","author":"Jansson","year":"2006","journal-title":"J. Physiol."},{"issue":"1","key":"10.1016\/j.placenta.2020.05.002_bib20","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1677\/joe.0.1740037","article-title":"Maternal undernutrition during late gestation-induced intrauterine growth restriction in the rat is associated with impaired placental GLUT3 expression, but does not correlate with endogenous corticosterone levels","volume":"174","author":"Lesage","year":"2002","journal-title":"J. Endocrinol."},{"issue":"7","key":"10.1016\/j.placenta.2020.05.002_bib21","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.3945\/jn.110.125658","article-title":"Parenteral administration of L-arginine prevents fetal growth restriction in undernourished ewes","volume":"140","author":"Lassala","year":"2010","journal-title":"J. Nutr."},{"issue":"2","key":"10.1016\/j.placenta.2020.05.002_bib22","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1095\/biolreprod.106.054684","article-title":"Placental growth throughout the last two thirds of pregnancy in sheep: vascular development and angiogenic factor expression","volume":"76","author":"Borowicz","year":"2007","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.placenta.2020.05.002_bib23","series-title":"Arginine Nutrition and Fetal Brown Adipose Tissue Development in Nutrient-Restricted Sheep","author":"Satterfield","year":"2011"},{"issue":"4","key":"10.1016\/j.placenta.2020.05.002_bib24","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1093\/jn\/135.4.714","article-title":"Dietary L-arginine supplementation reduces fat mass in Zucker diabetic fatty rats","volume":"135","author":"Fu","year":"2005","journal-title":"J. Nutr."},{"issue":"Pt 3","key":"10.1016\/j.placenta.2020.05.002_bib25","first-page":"717","article-title":"Urea synthesis in enterocytes of developing pigs","volume":"312","author":"Wu","year":"1995","journal-title":"Biochem. J."},{"issue":"11","key":"10.1016\/j.placenta.2020.05.002_bib26","doi-asserted-by":"crossref","first-page":"2859","DOI":"10.1093\/jn\/125.11.2859","article-title":"Developmental changes of free amino acid concentrations in fetal fluids of pigs","volume":"125","author":"Wu","year":"1995","journal-title":"J. Nutr."},{"issue":"6","key":"10.1016\/j.placenta.2020.05.002_bib27","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1161\/01.RES.52.6.730","article-title":"Fetal blood volume responses to acute fetal hemorrhage","volume":"52","author":"Brace","year":"1983","journal-title":"Circ. Res."},{"issue":"4","key":"10.1016\/j.placenta.2020.05.002_bib28","first-page":"H487","article-title":"Blood volume and its measurement in the chronically catheterized sheep fetus","volume":"244","author":"Brace","year":"1983","journal-title":"Am. J. Physiol."},{"issue":"2","key":"10.1016\/j.placenta.2020.05.002_bib29","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1530\/rep.0.1240289","article-title":"Evidence that absence of endometrial gland secretions in uterine gland knockout ewes compromises conceptus survival and elongation","volume":"124","author":"Gray","year":"2002","journal-title":"Reproduction"},{"issue":"11","key":"10.1016\/j.placenta.2020.05.002_bib30","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1002\/ar.23472","article-title":"The use of stereology method to estimate the volume of feto-maternal exchange area of the bovine placentome during gestation","volume":"299","author":"Adeyinka","year":"2016","journal-title":"Anat. Rec."},{"issue":"6","key":"10.1016\/j.placenta.2020.05.002_bib31","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.1095\/biolreprod62.6.1779","article-title":"Prolactin receptor and uterine milk protein expression in the ovine endometrium during the estrous cycle and pregnancy","volume":"62","author":"Stewart","year":"2000","journal-title":"Biol. Reprod."},{"issue":"6","key":"10.1016\/j.placenta.2020.05.002_bib32","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1095\/biolreprod.108.071787","article-title":"Progesterone regulates FGF10, MET, IGFBP1, and IGFBP3 in the endometrium of the ovine uterus","volume":"79","author":"Satterfield","year":"2008","journal-title":"Biol. Reprod."},{"issue":"5","key":"10.1016\/j.placenta.2020.05.002_bib33","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1203\/01.PDR.0000181381.82856.23","article-title":"Placental phenotypes of intrauterine growth","volume":"58","author":"Sibley","year":"2005","journal-title":"Pediatr. Res."},{"issue":"Suppl","key":"10.1016\/j.placenta.2020.05.002_bib34","doi-asserted-by":"crossref","first-page":"S70","DOI":"10.1016\/j.placenta.2009.12.020","article-title":"Review: adaptation in placental nutrient supply to meet fetal growth demand: implications for programming","volume":"31","author":"Sibley","year":"2010","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2020.05.002_bib35","doi-asserted-by":"crossref","first-page":"3659","DOI":"10.1113\/jphysiol.2011.208629","article-title":"Dietary composition programmes placental phenotype in mice","volume":"589","author":"Coan","year":"2011","journal-title":"J. Physiol."},{"issue":"Pt 1","key":"10.1016\/j.placenta.2020.05.002_bib36","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1113\/jphysiol.2006.104968","article-title":"Placental adaptive responses and fetal programming","volume":"572","author":"Myatt","year":"2006","journal-title":"J. Physiol."},{"issue":"3","key":"10.1016\/j.placenta.2020.05.002_bib37","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1210\/en.2010-1153","article-title":"Maternal protein restriction in the rat inhibits placental insulin, mTOR, and STAT3 signaling and down-regulates placental amino acid transporters","volume":"152","author":"Rosario","year":"2011","journal-title":"Endocrinology"},{"issue":"8\u20139","key":"10.1016\/j.placenta.2020.05.002_bib38","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/j.placenta.2007.05.002","article-title":"Regulation of placental nutrient transport--a review","volume":"28","author":"Jones","year":"2007","journal-title":"Placenta"},{"issue":"Suppl A","key":"10.1016\/j.placenta.2020.05.002_bib39","doi-asserted-by":"crossref","first-page":"S91","DOI":"10.1016\/j.placenta.2005.11.010","article-title":"IFPA 2005 Award in Placentology Lecture. Human placental transport in altered fetal growth: does the placenta function as a nutrient sensor? -- a review","volume":"27","author":"Jansson","year":"2006","journal-title":"Placenta"},{"issue":"Pt 1","key":"10.1016\/j.placenta.2020.05.002_bib40","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1113\/jphysiol.2005.104430","article-title":"Evidence for altered placental blood flow and vascularity in compromised pregnancies","volume":"572","author":"Reynolds","year":"2006","journal-title":"J. Physiol."},{"issue":"2","key":"10.1016\/j.placenta.2020.05.002_bib41","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0301-2115(01)00321-9","article-title":"Undernutrition during the first half of gestation increases the predominance of fetal tissue in late-gestation ovine placentomes","volume":"98","author":"Steyn","year":"2001","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"issue":"4","key":"10.1016\/j.placenta.2020.05.002_bib42","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1095\/biolreprod64.4.1033","article-title":"Angiogenesis in the placenta","volume":"64","author":"Reynolds","year":"2001","journal-title":"Biol. Reprod."},{"issue":"2 Pt 2","key":"10.1016\/j.placenta.2020.05.002_bib43","first-page":"R441","article-title":"Nitric oxide and pregnancy","volume":"272","author":"Sladek","year":"1997","journal-title":"Am. J. Physiol."},{"issue":"2","key":"10.1016\/j.placenta.2020.05.002_bib44","doi-asserted-by":"crossref","first-page":"R245","DOI":"10.1152\/ajpregu.00108.2002","article-title":"Possible mechanisms underlying pregnancy-induced changes in uterine artery endothelial function","volume":"284","author":"Bird","year":"2003","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"issue":"4","key":"10.1016\/j.placenta.2020.05.002_bib45","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1007\/s00726-008-0052-7","article-title":"Proline metabolism in the conceptus: implications for fetal growth and development","volume":"35","author":"Wu","year":"2008","journal-title":"Amino Acids"},{"issue":"5","key":"10.1016\/j.placenta.2020.05.002_bib46","doi-asserted-by":"crossref","first-page":"1626","DOI":"10.1095\/biolreprod.103.019067","article-title":"Developmental changes in polyamine levels and synthesis in the ovine conceptus","volume":"69","author":"Kwon","year":"2003","journal-title":"Biol. Reprod."},{"issue":"10","key":"10.1016\/j.placenta.2020.05.002_bib47","doi-asserted-by":"crossref","first-page":"5012","DOI":"10.1210\/en.2008-0084","article-title":"Molecular and morphological changes in placenta and embryo development associated with the inhibition of polyamine synthesis during midpregnancy in mice","volume":"149","author":"Lopez-Garcia","year":"2008","journal-title":"Endocrinology"},{"issue":"19","key":"10.1016\/j.placenta.2020.05.002_bib48","doi-asserted-by":"crossref","first-page":"6549","DOI":"10.1128\/MCB.21.19.6549-6558.2001","article-title":"The ornithine decarboxylase gene is essential for cell survival during early murine development","volume":"21","author":"Pendeville","year":"2001","journal-title":"Mol. Cell Biol."},{"issue":"12","key":"10.1016\/j.placenta.2020.05.002_bib49","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1016\/S0024-3205(01)01510-7","article-title":"Inhibition of placental ornithine decarboxylase by DL-alpha-difluoro- methyl ornithine causes fetal growth restriction in rat","volume":"70","author":"Ishida","year":"2002","journal-title":"Life Sci."},{"issue":"5","key":"10.1016\/j.placenta.2020.05.002_bib50","doi-asserted-by":"crossref","first-page":"849","DOI":"10.3945\/jn.111.138172","article-title":"Parenteral administration of L-arginine enhances fetal survival and growth in sheep carrying multiple fetuses","volume":"141","author":"Lassala","year":"2011","journal-title":"J. Nutr."},{"issue":"2\u20133","key":"10.1016\/j.placenta.2020.05.002_bib51","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1053\/plac.2002.0887","article-title":"Genes, development And evolution of the placenta","volume":"24","author":"Cross","year":"2003","journal-title":"Placenta"},{"issue":"Pt 3","key":"10.1016\/j.placenta.2020.05.002_bib52","first-page":"557","article-title":"The development of the placenta in the sheep and goat: an electron microscope study","volume":"105","author":"Lawn","year":"1969","journal-title":"J. Anat."},{"issue":"1","key":"10.1016\/j.placenta.2020.05.002_bib53","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.rvsc.2005.09.006","article-title":"A stereological method for estimating the feto-maternal exchange surface area in the bovine placentome at 135 days gestation","volume":"81","author":"Kannekens","year":"2006","journal-title":"Res. Vet. Sci."},{"issue":"11","key":"10.1016\/j.placenta.2020.05.002_bib54","doi-asserted-by":"crossref","first-page":"1873","DOI":"10.1002\/ar.21231","article-title":"Morphometric analysis of yak placentomes during gestation","volume":"293","author":"Liu","year":"2010","journal-title":"Anat. Rec."},{"issue":"3 Pt 1","key":"10.1016\/j.placenta.2020.05.002_bib55","first-page":"E349","article-title":"Effect of insulin on uptake of metabolic substrates by the sheep fetus","volume":"251","author":"Milley","year":"1986","journal-title":"Am. J. Physiol."},{"issue":"1","key":"10.1016\/j.placenta.2020.05.002_bib56","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1677\/joe.0.0960107","article-title":"Somatomedin activity and growth hormone levels in body fluids of the fetal pig: effect of chronic hyperinsulinaemia","volume":"96","author":"Spencer","year":"1983","journal-title":"J. Endocrinol."},{"issue":"12","key":"10.1016\/j.placenta.2020.05.002_bib57","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.2337\/diab.28.12.1058","article-title":"Chronic hyperinsulinemia in the fetal rhesus monkey: effects on fetal growth and composition","volume":"28","author":"Susa","year":"1979","journal-title":"Diabetes"},{"issue":"5","key":"10.1016\/j.placenta.2020.05.002_bib58","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1007\/BF00252765","article-title":"Effects on rat fetuses of intrauterine injections of insulin","volume":"20","author":"Angervall","year":"1981","journal-title":"Diabetologia"},{"issue":"Pt 3","key":"10.1016\/j.placenta.2020.05.002_bib59","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1113\/jphysiol.2007.142141","article-title":"Restriction of placental growth in sheep impairs insulin secretion but not sensitivity before birth","volume":"584","author":"Owens","year":"2007","journal-title":"J. Physiol."},{"issue":"4","key":"10.1016\/j.placenta.2020.05.002_bib60","first-page":"247","article-title":"Maternal insulin and placental 3-O-methyl glucose transport","volume":"8","author":"Rankin","year":"1986","journal-title":"J. Dev. Physiol."},{"issue":"3","key":"10.1016\/j.placenta.2020.05.002_bib61","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1210\/jc.2002-021332","article-title":"Leptin stimulates the activity of the system A amino acid transporter in human placental villous fragments","volume":"88","author":"Jansson","year":"2003","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"5","key":"10.1016\/j.placenta.2020.05.002_bib62","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.2337\/db09-0824","article-title":"Full-length adiponectin attenuates insulin signaling and inhibits insulin-stimulated amino Acid transport in human primary trophoblast cells","volume":"59","author":"Jones","year":"2010","journal-title":"Diabetes"},{"issue":"4 Pt 1","key":"10.1016\/j.placenta.2020.05.002_bib63","doi-asserted-by":"crossref","first-page":"C834","DOI":"10.1152\/ajpcell.1992.262.4.C834","article-title":"Amino acid transport by the cultured human placental trophoblast: effect of insulin on AIB transport","volume":"262","author":"Karl","year":"1992","journal-title":"Am. J. Physiol."},{"issue":"4","key":"10.1016\/j.placenta.2020.05.002_bib64","doi-asserted-by":"crossref","first-page":"460","DOI":"10.2174\/157016109789043973","article-title":"Insulin action on the human placental endothelium in normal and diabetic pregnancy","volume":"7","author":"Hiden","year":"2009","journal-title":"Curr. Vasc. Pharmacol."}],"container-title":["Placenta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400420301326?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400420301326?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T18:01:31Z","timestamp":1758909691000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0143400420301326"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7]]},"references-count":64,"alternative-id":["S0143400420301326"],"URL":"https:\/\/doi.org\/10.1016\/j.placenta.2020.05.002","relation":{},"ISSN":["0143-4004"],"issn-type":[{"value":"0143-4004","type":"print"}],"subject":[],"published":{"date-parts":[[2020,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Adaptive responses to maternal nutrient restriction alter placental transport in ewes","name":"articletitle","label":"Article Title"},{"value":"Placenta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.placenta.2020.05.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}