{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T03:37:03Z","timestamp":1781581023586,"version":"3.54.5"},"reference-count":141,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,6,18]],"date-time":"2024-06-18T00:00:00Z","timestamp":1718668800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["509140"],"award-info":[{"award-number":["509140"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["509178"],"award-info":[{"award-number":["509178"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Placenta"],"published-print":{"date-parts":[[2024,11]]},"DOI":"10.1016\/j.placenta.2024.06.010","type":"journal-article","created":{"date-parts":[[2024,6,18]],"date-time":"2024-06-18T12:16:48Z","timestamp":1718713008000},"page":"28-36","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Homeobox genes in the human placenta: Twists and turns on the path to find novel targets"],"prefix":"10.1016","volume":"157","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2535-5134","authenticated-orcid":false,"given":"Padma","family":"Murthi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bill","family":"Kalionis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6761","key":"10.1016\/j.placenta.2024.06.010_bib1","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1136\/bmj.301.6761.1111","article-title":"The fetal and infant origins of adult disease","volume":"301","author":"Barker","year":"1990","journal-title":"BMJ"},{"issue":"2","key":"10.1016\/j.placenta.2024.06.010_bib2","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.placenta.2013.11.015","article-title":"Association between first-trimester placental volume and birth weight","volume":"35","author":"Effendi","year":"2014","journal-title":"Placenta"},{"issue":"3","key":"10.1016\/j.placenta.2024.06.010_bib3","doi-asserted-by":"crossref","first-page":"253 e1","DOI":"10.1016\/j.ajog.2014.02.033","article-title":"First-trimester placental ultrasound and maternal serum markers as predictors of small-for-gestational-age infants","volume":"211","author":"Schwartz","year":"2014","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.placenta.2024.06.010_bib4","series-title":"Obstetrics: Normal and Problem Pregnancies","first-page":"771","article-title":"Intrauterine growth restriction","author":"Baschat","year":"2007"},{"issue":"3","key":"10.1016\/j.placenta.2024.06.010_bib5","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.ajog.2010.08.009","article-title":"The \"Great Obstetrical Syndromes\" are associated with disorders of deep placentation","volume":"204","author":"Brosens","year":"2011","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.placenta.2024.06.010_bib6","series-title":"Fetal and Neonatal Physiology","first-page":"133","article-title":"Mechanisms of transfer across the human placenta","author":"Jones","year":"2011"},{"issue":"3","key":"10.1016\/j.placenta.2024.06.010_bib7","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1067\/mob.2002.125243","article-title":"Decreased vascularization and cell proliferation in placentas of intrauterine growth-restricted fetuses with abnormal umbilical artery flow velocity waveforms","volume":"187","author":"Chen","year":"2002","journal-title":"Am. J. Obstet. Gynecol."},{"issue":"9","key":"10.1016\/j.placenta.2024.06.010_bib8","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1016\/j.placenta.2008.07.003","article-title":"Live and let die - regulation of villous trophoblast apoptosis in normal and abnormal pregnancies","volume":"29","author":"Heazell","year":"2008","journal-title":"Placenta"},{"issue":"2","key":"10.1016\/j.placenta.2024.06.010_bib9","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1007\/s10495-010-0551-3","article-title":"Intra-uterine growth restriction is associated with increased apoptosis and altered expression of proteins in the p53 pathway in villous trophoblast","volume":"16","author":"Heazell","year":"2011","journal-title":"Apoptosis"},{"issue":"3","key":"10.1016\/j.placenta.2024.06.010_bib10","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1111\/j.1600-0897.2010.00837.x","article-title":"Placental apoptosis in health and disease","volume":"64","author":"Sharp","year":"2010","journal-title":"Am. J. Reprod. Immunol."},{"issue":"7","key":"10.1016\/j.placenta.2024.06.010_bib11","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1111\/j.1471-0528.1981.tb01268.x","article-title":"An ultrastructural study of utero-placental spiral arteries in hypertensive and normotensive pregnancy and fetal growth retardation","volume":"88","author":"Sheppard","year":"1981","journal-title":"Br. J. Obstet. Gynaecol."},{"issue":"3","key":"10.1016\/j.placenta.2024.06.010_bib12","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.bpobgyn.2010.10.016","article-title":"Oxidative stress","volume":"25","author":"Burton","year":"2011","journal-title":"Best Pract. Res. Clin. Obstet. Gynaecol."},{"issue":"Suppl A","key":"10.1016\/j.placenta.2024.06.010_bib13","doi-asserted-by":"crossref","first-page":"S141","DOI":"10.1016\/j.placenta.2006.01.011","article-title":"Trophoblast differentiation: progenitor cells, fusion and migration -- a workshop report","volume":"27","author":"Aplin","year":"2006","journal-title":"Placenta"},{"issue":"9","key":"10.1016\/j.placenta.2024.06.010_bib14","doi-asserted-by":"crossref","first-page":"4213","DOI":"10.1210\/jc.2002-020195","article-title":"Human placental vascular development: vasculogenic and angiogenic (branching and nonbranching) transformation is regulated by vascular endothelial growth factor-A, angiopoietin-1, and angiopoietin-2","volume":"87","author":"Geva","year":"2002","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"2 Suppl 1","key":"10.1016\/j.placenta.2024.06.010_bib15","first-page":"183","article-title":"Growth factors and their receptors: fundamental molecules for human placental development","volume":"110","author":"Marzioni","year":"2005","journal-title":"Ital. J. Anat Embryol."},{"issue":"2","key":"10.1016\/j.placenta.2024.06.010_bib16","first-page":"151","article-title":"Hypoxia down-regulates placenta growth factor, whereas fetal growth restriction up-regulates placenta growth factor expression: molecular evidence for \"placental hyperoxia\" in intrauterine growth restriction","volume":"79","author":"Khaliq","year":"1999","journal-title":"Lab. Invest."},{"issue":"6","key":"10.1016\/j.placenta.2024.06.010_bib17","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1053\/beog.2000.0139","article-title":"Baillieres Best Pract. Res. Clin. Obstet. Gynaecol.","volume":"14","author":"Ahmed","year":"2000","journal-title":"Baillieres Best Pract Res Clin Obstet Gynaecol"},{"issue":"1","key":"10.1016\/j.placenta.2024.06.010_bib18","doi-asserted-by":"crossref","first-page":"F21","DOI":"10.1136\/fn.76.1.F21","article-title":"Third trimester fetal growth and measures of carbohydrate and lipid metabolism in umbilical venous blood at term","volume":"76","author":"Spencer","year":"1997","journal-title":"Arch. Dis. Child. Fetal Neonatal Ed."},{"issue":"Suppl A","key":"10.1016\/j.placenta.2024.06.010_bib19","doi-asserted-by":"crossref","first-page":"S83","DOI":"10.1053\/plac.2001.0648","article-title":"Key regulatory transcription factors involved in placental trophoblast development--a review","volume":"22","author":"Knofler","year":"2001","journal-title":"Placenta"},{"issue":"2\u20133","key":"10.1016\/j.placenta.2024.06.010_bib20","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1387\/ijdb.082769mk","article-title":"Critical growth factors and signalling pathways controlling human trophoblast invasion","volume":"54","author":"Knofler","year":"2010","journal-title":"Int. J. Dev. Biol."},{"issue":"Suppl A","key":"10.1016\/j.placenta.2024.06.010_bib21","doi-asserted-by":"crossref","first-page":"S71","DOI":"10.1053\/plac.1999.0531","article-title":"Novel genes and transcription factors in placental development--a workshop report","volume":"21","author":"Knofler","year":"2000","journal-title":"Placenta"},{"issue":"Suppl A","key":"10.1016\/j.placenta.2024.06.010_bib22","doi-asserted-by":"crossref","first-page":"S49","DOI":"10.1016\/j.placenta.2005.02.001","article-title":"Trophoblast signalling: knowns and unknowns--a workshop report","volume":"26","author":"Knofler","year":"2005","journal-title":"Placenta"},{"issue":"42","key":"10.1016\/j.placenta.2024.06.010_bib23","doi-asserted-by":"crossref","first-page":"28729","DOI":"10.1074\/jbc.M109.016840","article-title":"GATA3 is selectively expressed in the trophectoderm of peri-implantation embryo and directly regulates Cdx2 gene expression","volume":"284","author":"Home","year":"2009","journal-title":"J. Biol. Chem."},{"issue":"Suppl 1","key":"10.1016\/j.placenta.2024.06.010_bib24","doi-asserted-by":"crossref","first-page":"S61","DOI":"10.1016\/j.placenta.2017.05.005","article-title":"GATA factors: master regulators of gene expression in trophoblast progenitors","volume":"60","author":"Paul","year":"2017","journal-title":"Placenta"},{"issue":"Pt 3","key":"10.1016\/j.placenta.2024.06.010_bib25","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1042\/bj3610641","article-title":"Human Hand1 basic helix-loop-helix (bHLH) protein: extra-embryonic expression pattern, interaction partners and identification of its transcriptional repressor domains","volume":"361","author":"Knofler","year":"2002","journal-title":"Biochem. J."},{"issue":"Suppl A","key":"10.1016\/j.placenta.2024.06.010_bib26","doi-asserted-by":"crossref","first-page":"S25","DOI":"10.1053\/plac.1999.0522","article-title":"Oxygen and placental development during the first trimester: implications for the pathophysiology of pre-eclampsia","volume":"21","author":"Caniggia","year":"2000","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2024.06.010_bib27","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.placenta.2017.03.010","article-title":"Hypoxia and HIF pathway in cancer and the placenta","volume":"56","author":"Macklin","year":"2017","journal-title":"Placenta"},{"issue":"11","key":"10.1016\/j.placenta.2024.06.010_bib28","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1016\/j.placenta.2010.08.008","article-title":"Regulation of hypoxia inducible factors (HIF) in hypoxia and normoxia during placental development","volume":"31","author":"Patel","year":"2010","journal-title":"Placenta"},{"issue":"1","key":"10.1016\/j.placenta.2024.06.010_bib29","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.rbmo.2012.02.015","article-title":"The role of transcription factor Tcfap2c\/TFAP2C in trophectoderm development","volume":"25","author":"Kuckenberg","year":"2012","journal-title":"Reprod. Biomed. Online"},{"issue":"18","key":"10.1016\/j.placenta.2024.06.010_bib30","doi-asserted-by":"crossref","first-page":"3163","DOI":"10.1128\/MCB.00118-15","article-title":"Dynamic regulation of AP-1 transcriptional complexes directs trophoblast differentiation","volume":"35","author":"Kubota","year":"2015","journal-title":"Mol. Cell Biol."},{"issue":"1","key":"10.1016\/j.placenta.2024.06.010_bib31","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0029745","article-title":"AP-1 transcription factors, mucin-type molecules and MMPs regulate the IL-11 mediated invasiveness of JEG-3 and HTR-8\/SVneo trophoblastic cells","volume":"7","author":"Suman","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.placenta.2024.06.010_bib32","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/1471-2199-8-14","article-title":"Ets-2 and C\/EBP-beta are important mediators of ovine trophoblast Kunitz domain protein-1 gene expression in trophoblast","volume":"8","author":"Chakrabarty","year":"2007","journal-title":"BMC Mol. Biol."},{"issue":"5","key":"10.1016\/j.placenta.2024.06.010_bib33","doi-asserted-by":"crossref","first-page":"1851","DOI":"10.1210\/en.2014-1760","article-title":"ETS1 induces human trophoblast differentiation","volume":"156","author":"Kessler","year":"2015","journal-title":"Endocrinology"},{"issue":"1","key":"10.1016\/j.placenta.2024.06.010_bib34","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.ydbio.2007.09.024","article-title":"Ets2 is required for trophoblast stem cell self-renewal","volume":"312","author":"Wen","year":"2007","journal-title":"Dev. Biol."},{"key":"10.1016\/j.placenta.2024.06.010_bib35","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0070-2153(08)60363-4","article-title":"Homeobox genes in cardiovascular development","volume":"40","author":"Patterson","year":"1998","journal-title":"Curr. Top. Dev. Biol."},{"issue":"1","key":"10.1016\/j.placenta.2024.06.010_bib36","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S0378-1119(96)00706-8","article-title":"Isolation and identification of homeobox genes from the human placenta including a novel member of the Distal-less family, DLX4","volume":"187","author":"Quinn","year":"1997","journal-title":"Gene"},{"issue":"2","key":"10.1016\/j.placenta.2024.06.010_bib37","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1006\/scdb.2000.0156","article-title":"Genetic insights into trophoblast differentiation and placental morphogenesis","volume":"11","author":"Cross","year":"2000","journal-title":"Semin. Cell Dev. Biol."},{"issue":"3","key":"10.1016\/j.placenta.2024.06.010_bib38","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1038\/3129","article-title":"Esx1 is an X-chromosome-imprinted regulator of placental development and fetal growth","volume":"20","author":"Li","year":"1998","journal-title":"Nat. Genet."},{"key":"10.1016\/j.placenta.2024.06.010_bib39","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1146\/annurev.bi.63.070194.002415","article-title":"Homeodomain proteins","volume":"63","author":"Gehring","year":"1994","journal-title":"Annu. Rev. Biochem."},{"issue":"2","key":"10.1016\/j.placenta.2024.06.010_bib40","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1002\/(SICI)1521-1878(199802)20:2<116::AID-BIES4>3.0.CO;2-R","article-title":"Shaping animal body plans in development and evolution by modulation of Hox expression patterns","volume":"20","author":"Gellon","year":"1998","journal-title":"Bioessays"},{"issue":"1","key":"10.1016\/j.placenta.2024.06.010_bib41","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1055\/s-2000-13478","article-title":"The role of HOX genes in the development and function of the female reproductive tract","volume":"18","author":"Taylor","year":"2000","journal-title":"Semin. Reprod. Med."},{"issue":"2","key":"10.1016\/j.placenta.2024.06.010_bib42","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1002\/jcp.1115","article-title":"Homeobox genes in normal and malignant cells","volume":"188","author":"Cillo","year":"2001","journal-title":"J. Cell. Physiol."},{"issue":"17","key":"10.1016\/j.placenta.2024.06.010_bib43","doi-asserted-by":"crossref","first-page":"3321","DOI":"10.1242\/dev.124.17.3321","article-title":"A genetic screen for modifiers of Deformed homeotic function identifies novel genes required for head development","volume":"124","author":"Gellon","year":"1997","journal-title":"Development"},{"issue":"5461","key":"10.1016\/j.placenta.2024.06.010_bib44","doi-asserted-by":"crossref","first-page":"2216","DOI":"10.1126\/science.287.5461.2216","article-title":"A brief history of Drosophila's contributions to genome research","volume":"287","author":"Rubin","year":"2000","journal-title":"Science"},{"key":"10.1016\/j.placenta.2024.06.010_bib45","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1101\/SQB.1985.050.01.021","article-title":"Regulation of the genes of the bithorax complex in Drosophila","volume":"50","author":"Lewis","year":"1985","journal-title":"Cold Spring Harbor Symp. Quant. Biol."},{"issue":"6107","key":"10.1016\/j.placenta.2024.06.010_bib46","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1038\/325816a0","article-title":"Redesigning the body plan of Drosophila by ectopic expression of the homoeotic gene Antennapedia","volume":"325","author":"Schneuwly","year":"1987","journal-title":"Nature"},{"issue":"3","key":"10.1016\/j.placenta.2024.06.010_bib47","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1093\/genetics\/138.3.709","article-title":"The Drosophila homeotic mutation Nasobemia (AntpNs) and its revertants: an analysis of mutational reversion","volume":"138","author":"Talbert","year":"1994","journal-title":"Genetics"},{"key":"10.1016\/j.placenta.2024.06.010_bib48","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2021.718308","article-title":"Homeotic genes: clustering, modularity, and diversity","volume":"9","author":"Hajirnis","year":"2021","journal-title":"Front. Cell Dev. Biol."},{"issue":"10","key":"10.1016\/j.placenta.2024.06.010_bib49","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1002\/mrd.22212","article-title":"CDX2 regulates multiple trophoblast genes in bovine trophectoderm CT-1 cells","volume":"80","author":"Schiffmacher","year":"2013","journal-title":"Mol. Reprod. Dev."},{"issue":"1","key":"10.1016\/j.placenta.2024.06.010_bib50","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1067\/mob.2002.122850","article-title":"Expression of homeobox gene transcripts in trophoblastic cells","volume":"187","author":"Zhang","year":"2002","journal-title":"Am. J. Obstet. Gynecol."},{"issue":"5","key":"10.1016\/j.placenta.2024.06.010_bib51","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1000073","article-title":"HOXA13 Is essential for placental vascular patterning and labyrinth endothelial specification","volume":"4","author":"Shaut","year":"2008","journal-title":"PLoS Genet."},{"key":"10.1016\/j.placenta.2024.06.010_bib52","doi-asserted-by":"crossref","first-page":"570","DOI":"10.3389\/fendo.2018.00570","article-title":"Regulation of placental development and its impact on fetal growth-new insights from mouse models","volume":"9","author":"Woods","year":"2018","journal-title":"Front. Endocrinol."},{"issue":"7","key":"10.1016\/j.placenta.2024.06.010_bib53","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1038\/35080570","article-title":"Placental development: lessons from mouse mutants","volume":"2","author":"Rossant","year":"2001","journal-title":"Nat. Rev. Genet."},{"issue":"5","key":"10.1016\/j.placenta.2024.06.010_bib54","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1023\/A:1012085713898","article-title":"Use of transgenic mice model for understanding the placentation: towards clinical applications in human obstetrical pathologies?","volume":"10","author":"Sapin","year":"2001","journal-title":"Transgenic Res."},{"issue":"4","key":"10.1016\/j.placenta.2024.06.010_bib55","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/S1043-2760(01)00375-7","article-title":"Genes governing placental development","volume":"12","author":"Hemberger","year":"2001","journal-title":"Trends Endocrinol. Metabol."},{"issue":"2\u20133","key":"10.1016\/j.placenta.2024.06.010_bib56","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1053\/plac.2002.0887","article-title":"Genes, development and evolution of the placenta","volume":"24","author":"Cross","year":"2003","journal-title":"Placenta"},{"issue":"1","key":"10.1016\/j.placenta.2024.06.010_bib57","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1073\/pnas.96.1.162","article-title":"Placental failure in mice lacking the homeobox gene Dlx3","volume":"96","author":"Morasso","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"Suppl A","key":"10.1016\/j.placenta.2024.06.010_bib58","doi-asserted-by":"crossref","first-page":"S104","DOI":"10.1053\/plac.2002.0929","article-title":"Regulatory transcription factors controlling function and differentiation of human trophoblast--a review","volume":"24","author":"Loregger","year":"2003","journal-title":"Placenta"},{"issue":"8","key":"10.1016\/j.placenta.2024.06.010_bib59","first-page":"617","article-title":"Analysis of a candidate gene associated with growth suppression of choriocarcinoma and differentiation of trophoblasts","volume":"49","author":"Asanoma","year":"2004","journal-title":"J. Reprod. Med."},{"issue":"3","key":"10.1016\/j.placenta.2024.06.010_bib60","doi-asserted-by":"crossref","first-page":"245","DOI":"10.2174\/1389203013381116","article-title":"Life and death in the placenta: new peptides and genes regulating human syncytiotrophoblast and extravillous cytotrophoblast lineage formation and renewal","volume":"2","author":"Morrish","year":"2001","journal-title":"Curr. Protein Pept. Sci."},{"issue":"1","key":"10.1016\/j.placenta.2024.06.010_bib61","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0143-4004(98)90103-5","article-title":"A distal-less class homeobox gene, DLX4, is a candidate for regulating epithelial-mesenchymal cell interactions in the human placenta","volume":"19","author":"Quinn","year":"1998","journal-title":"Placenta"},{"issue":"3","key":"10.1016\/j.placenta.2024.06.010_bib62","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1071\/RD07159","article-title":"Homeodomain protein HLX is expressed primarily in cytotrophoblast cell types in the early pregnancy human placenta","volume":"20","author":"Rajaraman","year":"2008","journal-title":"Reprod. Fertil. Dev."},{"issue":"5","key":"10.1016\/j.placenta.2024.06.010_bib63","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1093\/molehr\/gal037","article-title":"Homeobox gene ESX1L expression is decreased in human pre-term idiopathic fetal growth restriction","volume":"12","author":"Murthi","year":"2006","journal-title":"Mol. Hum. Reprod."},{"issue":"8","key":"10.1016\/j.placenta.2024.06.010_bib64","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/j.placenta.2010.05.003","article-title":"Homeobox gene distal-less 3 is expressed in proliferating and differentiating cells of the human placenta","volume":"31","author":"Chui","year":"2010","journal-title":"Placenta"},{"issue":"12","key":"10.1016\/j.placenta.2024.06.010_bib65","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1093\/molehr\/gal087","article-title":"Homeobox gene DLX4 expression is increased in idiopathic human fetal growth restriction","volume":"12","author":"Murthi","year":"2006","journal-title":"Mol. Hum. Reprod."},{"issue":"10","key":"10.1016\/j.placenta.2024.06.010_bib66","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1093\/molehr\/gat042","article-title":"Homeobox gene transforming growth factor beta-induced factor-1 (TGIF-1) is a regulator of villous trophoblast differentiation and its expression is increased in human idiopathic fetal growth restriction","volume":"19","author":"Pathirage","year":"2013","journal-title":"Mol. Hum. Reprod."},{"issue":"5","key":"10.1016\/j.placenta.2024.06.010_bib67","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1530\/REP-14-0646","article-title":"Isolation and characterisation of a novel trophoblast side-population from first trimester placentae","volume":"150","author":"James","year":"2015","journal-title":"Reproduction"},{"issue":"2","key":"10.1016\/j.placenta.2024.06.010_bib68","doi-asserted-by":"crossref","first-page":"511","DOI":"10.2353\/ajpath.2006.050637","article-title":"Homeobox gene HLX1 expression is decreased in idiopathic human fetal growth restriction","volume":"168","author":"Murthi","year":"2006","journal-title":"Am. J. Pathol."},{"issue":"10","key":"10.1016\/j.placenta.2024.06.010_bib69","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/j.placenta.2011.07.007","article-title":"Homeobox gene Distal-less 3 (DLX3) is a regulator of villous cytotrophoblast differentiation","volume":"32","author":"Chui","year":"2011","journal-title":"Placenta"},{"issue":"6\u20137","key":"10.1016\/j.placenta.2024.06.010_bib70","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.placenta.2005.05.011","article-title":"Sequential steps during vasculogenesis and angiogenesis in the very early human placenta","volume":"27","author":"Demir","year":"2006","journal-title":"Placenta"},{"issue":"1","key":"10.1016\/j.placenta.2024.06.010_bib71","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S0301-2115(00)00423-1","article-title":"Development of the placental villous tree and its consequences for fetal growth","volume":"92","author":"Kingdom","year":"2000","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"issue":"2\u20133","key":"10.1016\/j.placenta.2024.06.010_bib72","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.placenta.2006.02.012","article-title":"Homeobox genes are differentially expressed in macrovascular human umbilical vein endothelial cells and microvascular placental endothelial cells","volume":"28","author":"Murthi","year":"2007","journal-title":"Placenta"},{"issue":"7","key":"10.1016\/j.placenta.2024.06.010_bib73","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/j.placenta.2008.04.006","article-title":"Novel homeobox genes are differentially expressed in placental microvascular endothelial cells compared with macrovascular cells","volume":"29","author":"Murthi","year":"2008","journal-title":"Placenta"},{"issue":"9","key":"10.1016\/j.placenta.2024.06.010_bib74","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1093\/molehr\/gaz047","article-title":"The role of insulin-like growth factor 2 receptor-mediated homeobox gene expression in human placental apoptosis, and its implications in idiopathic fetal growth restriction","volume":"25","author":"Harris","year":"2019","journal-title":"Mol. Hum. Reprod."},{"issue":"1","key":"10.1016\/j.placenta.2024.06.010_bib75","doi-asserted-by":"crossref","first-page":"4523","DOI":"10.1038\/s41598-017-04776-5","article-title":"Increased methylation and decreased expression of homeobox genes TLX1, HOXA10 and DLX5 in human placenta are associated with trophoblast differentiation","volume":"7","author":"Novakovic","year":"2017","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.placenta.2024.06.010_bib76","doi-asserted-by":"crossref","first-page":"645","DOI":"10.2119\/molmed.2015.00071","article-title":"An EG-VEGF-dependent decrease in homeobox gene NKX3.1 contributes to cytotrophoblast dysfunction: a possible mechanism in human fetal growth restriction","volume":"21","author":"Murthi","year":"2015","journal-title":"Mol. Med."},{"issue":"5","key":"10.1016\/j.placenta.2024.06.010_bib77","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1530\/REP-16-0068","article-title":"Homeobox gene TGIF-1 is increased in placental endothelial cells of human fetal growth restriction","volume":"152","author":"Gunatillake","year":"2016","journal-title":"Reproduction"},{"issue":"11","key":"10.1016\/j.placenta.2024.06.010_bib78","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1177\/1933719114526471","article-title":"A novel combination of homeobox genes is expressed in mesenchymal chorionic stem\/stromal cells in first trimester and term pregnancies","volume":"21","author":"Liu","year":"2014","journal-title":"Reprod. Sci."},{"issue":"5","key":"10.1016\/j.placenta.2024.06.010_bib79","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1007\/s12265-012-9371-x","article-title":"The vascular stem cell niche","volume":"5","author":"Gomez-Gaviro","year":"2012","journal-title":"J. Cardiovasc. Transl. Res."},{"issue":"7","key":"10.1016\/j.placenta.2024.06.010_bib80","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1002\/jcp.25255","article-title":"MSCs: the sentinel and safe-guards of injury","volume":"231","author":"Caplan","year":"2016","journal-title":"J. Cell. Physiol."},{"issue":"1","key":"10.1016\/j.placenta.2024.06.010_bib81","doi-asserted-by":"crossref","first-page":"278","DOI":"10.2353\/ajpath.2010.090187","article-title":"Downstream targets of homeobox gene HLX show altered expression in human idiopathic fetal growth restriction","volume":"176","author":"Rajaraman","year":"2010","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.placenta.2024.06.010_bib82","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.placenta.2016.12.007","article-title":"HTR-8\/SVneo cell line contains a mixed population of cells","volume":"50","author":"Abou-Kheir","year":"2017","journal-title":"Placenta"},{"issue":"1\u20132","key":"10.1016\/j.placenta.2024.06.010_bib83","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.mce.2013.06.032","article-title":"Downstream targets of the homeobox gene DLX3 are differentially expressed in the placentae of pregnancies affected by human idiopathic fetal growth restriction","volume":"377","author":"Chui","year":"2013","journal-title":"Mol. Cell. Endocrinol."},{"issue":"Suppl","key":"10.1016\/j.placenta.2024.06.010_bib84","doi-asserted-by":"crossref","first-page":"S55","DOI":"10.1016\/j.placenta.2010.11.019","article-title":"Effects of calcium, magnesium, low-dose aspirin and low-molecular-weight heparin on the release of PP13 from placental explants","volume":"32","author":"Grimpel","year":"2011","journal-title":"Placenta"},{"issue":"5","key":"10.1016\/j.placenta.2024.06.010_bib85","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/j.placenta.2010.02.017","article-title":"Effects of vitamins C and E, acetylsalicylic acid and heparin on fusion, beta-hCG and PP13 expression in BeWo cells","volume":"31","author":"Orendi","year":"2010","journal-title":"Placenta"},{"issue":"Suppl","key":"10.1016\/j.placenta.2024.06.010_bib86","doi-asserted-by":"crossref","first-page":"S49","DOI":"10.1016\/j.placenta.2010.11.023","article-title":"Placental and trophoblastic in vitro models to study preventive and therapeutic agents for preeclampsia","volume":"32","author":"Orendi","year":"2011","journal-title":"Placenta"},{"issue":"10","key":"10.1016\/j.placenta.2024.06.010_bib87","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.tem.2012.05.006","article-title":"EG-VEGF: a key endocrine factor in placental development","volume":"23","author":"Brouillet","year":"2012","journal-title":"Trends Endocrinol. Metabol."},{"issue":"3","key":"10.1016\/j.placenta.2024.06.010_bib88","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1007\/s00018-012-1141-z","article-title":"EG-VEGF controls placental growth and survival in normal and pathological pregnancies: case of fetal growth restriction (FGR)","volume":"70","author":"Brouillet","year":"2013","journal-title":"Cell. Mol. Life Sci."},{"issue":"4","key":"10.1016\/j.placenta.2024.06.010_bib89","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1210\/er.2005-0018","article-title":"Endocrine regulation of HOX genes","volume":"27","author":"Daftary","year":"2006","journal-title":"Endocr. Rev."},{"issue":"4","key":"10.1016\/j.placenta.2024.06.010_bib90","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1095\/biolreprod.109.078634","article-title":"Homeobox gene HLX is a regulator of HGF\/c-met-mediated migration of human trophoblast-derived cell lines","volume":"83","author":"Rajaraman","year":"2010","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.placenta.2024.06.010_bib91","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/1457398","article-title":"The imbalance expression of DLX3 may perform critical function in the occurrence and progression of preeclampsia","volume":"2022","author":"Hou","year":"2022","journal-title":"Comput. Math. Methods Med."},{"issue":"6","key":"10.1016\/j.placenta.2024.06.010_bib92","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1080\/01443615.2020.1819211","article-title":"The effect of gestational diabetes on identification of key genes and pathways in human umbilical vein endothelial cell by integrated bioinformatics analysis","volume":"41","author":"Liu","year":"2021","journal-title":"J. Obstet. Gynaecol."},{"issue":"2","key":"10.1016\/j.placenta.2024.06.010_bib93","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1093\/molehr\/gay053","article-title":"ZEB2, a master regulator of the epithelial-mesenchymal transition, mediates trophoblast differentiation","volume":"25","author":"DaSilva-Arnold","year":"2019","journal-title":"Mol. Hum. Reprod."},{"issue":"3","key":"10.1016\/j.placenta.2024.06.010_bib94","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/S0090-8258(03)00357-3","article-title":"Expression of HOX gene products in normal and abnormal trophoblastic tissue","volume":"90","author":"Amesse","year":"2003","journal-title":"Gynecol. Oncol."},{"key":"10.1016\/j.placenta.2024.06.010_bib95","series-title":"Molecular Cell Biology","author":"Lodish","year":"2003"},{"issue":"3","key":"10.1016\/j.placenta.2024.06.010_bib96","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1038\/3129","article-title":"Esx1 is an X-chromosome-imprinted regulator of placental development and fetal growth","volume":"20","author":"Li","year":"1998","journal-title":"Nat. Genet."},{"issue":"1","key":"10.1016\/j.placenta.2024.06.010_bib97","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.ydbio.2015.10.015","article-title":"The imprinted Phlda2 gene modulates a major endocrine compartment of the placenta to regulate placental demands for maternal resources","volume":"409","author":"Tunster","year":"2016","journal-title":"Dev. Biol."},{"issue":"2","key":"10.1016\/j.placenta.2024.06.010_bib98","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.placenta.2011.11.018","article-title":"Ontogeny of growth-regulating genes in the placenta","volume":"33","author":"Kumar","year":"2012","journal-title":"Placenta"},{"issue":"6\u20137","key":"10.1016\/j.placenta.2024.06.010_bib99","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/j.placenta.2005.07.004","article-title":"Unbalanced placental expression of imprinted genes in human intrauterine growth restriction","volume":"27","author":"McMinn","year":"2006","journal-title":"Placenta"},{"issue":"34","key":"10.1016\/j.placenta.2024.06.010_bib100","doi-asserted-by":"crossref","first-page":"32124","DOI":"10.1074\/jbc.M302847200","article-title":"Protein kinase B alpha\/Akt1 regulates placental development and fetal growth","volume":"278","author":"Yang","year":"2003","journal-title":"J. Biol. Chem."},{"issue":"3","key":"10.1016\/j.placenta.2024.06.010_bib101","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1210\/en.2004-1332","article-title":"Intrauterine growth restriction in humans is associated with abnormalities in placental insulin-like growth factor signaling","volume":"146","author":"Laviola","year":"2005","journal-title":"Endocrinology"},{"issue":"1","key":"10.1016\/j.placenta.2024.06.010_bib102","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1073\/pnas.96.1.162","article-title":"Placental failure in mice lacking the homeobox gene Dlx3","volume":"96","author":"Morasso","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"5221","key":"10.1016\/j.placenta.2024.06.010_bib103","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1126\/science.7618085","article-title":"Strain-dependent epithelial defects in mice lacking the EGF receptor","volume":"269","author":"Sibilia","year":"1995","journal-title":"Science"},{"key":"10.1016\/j.placenta.2024.06.010_bib104","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1126\/science.7618084","article-title":"Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype","volume":"269","author":"Threadgill","year":"1995","journal-title":"Science"},{"issue":"3","key":"10.1016\/j.placenta.2024.06.010_bib105","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1172\/JCI117067","article-title":"Alterations of human placental epidermal growth factor receptor in intrauterine growth retardation","volume":"93","author":"Fondacci","year":"1994","journal-title":"J. Clin. Invest."},{"issue":"6","key":"10.1016\/j.placenta.2024.06.010_bib106","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1002\/jcb.25789","article-title":"Placental-specific overexpression of sFlt-1 alters trophoblast differentiation and nutrient transporter expression in an IUGR mouse model","volume":"118","author":"Kuhnel","year":"2017","journal-title":"J. Cell. Biochem."},{"issue":"1","key":"10.1016\/j.placenta.2024.06.010_bib107","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1210\/jc.2007-1042","article-title":"Placental expression of soluble fms-like tyrosine kinase 1 is increased in singletons and twin pregnancies with intrauterine growth restriction","volume":"93","author":"Nevo","year":"2008","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.placenta.2024.06.010_bib108","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1038\/376066a0","article-title":"Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium","volume":"376","author":"Fong","year":"1995","journal-title":"Nature"},{"issue":"2\u20133","key":"10.1016\/j.placenta.2024.06.010_bib109","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1053\/plac.2001.0757","article-title":"Placental expression of VEGF, PlGF and their receptors in a model of placental insufficiency-intrauterine growth restriction (PI-IUGR)","volume":"23","author":"Regnault","year":"2002","journal-title":"Placenta"},{"issue":"3","key":"10.1016\/j.placenta.2024.06.010_bib110","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1038\/77076","article-title":"The glial cells missing-1 protein is essential for branching morphogenesis in the chorioallantoic placenta","volume":"25","author":"Anson-Cartwright","year":"2000","journal-title":"Nat. Genet."},{"issue":"5","key":"10.1016\/j.placenta.2024.06.010_bib111","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1038\/cdd.2009.1","article-title":"Glial cell missing-1 transcription factor is required for the differentiation of the human trophoblast","volume":"16","author":"Baczyk","year":"2009","journal-title":"Cell Death Differ."},{"issue":"4","key":"10.1016\/j.placenta.2024.06.010_bib112","doi-asserted-by":"crossref","first-page":"e2730","DOI":"10.1038\/cddis.2017.127","article-title":"p45 NF-E2 regulates syncytiotrophoblast differentiation by post-translational GCM1 modifications in human intrauterine growth restriction","volume":"8","author":"Kohli","year":"2017","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.placenta.2024.06.010_bib113","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1038\/373699a0","article-title":"Scatter factor\/hepatocyte growth factor is essential for liver development","volume":"373","author":"Schmidt","year":"1995","journal-title":"Nature"},{"key":"10.1016\/j.placenta.2024.06.010_bib114","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1038\/373702a0","article-title":"Placental defect and embryonic lethality in mice lacking hepatocyte growth factor\/scatter factor","volume":"373","author":"Uehara","year":"1995","journal-title":"Nature"},{"issue":"4","key":"10.1016\/j.placenta.2024.06.010_bib115","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1016\/S0002-9440(10)65658-1","article-title":"Ontogeny of hepatocyte growth factor (HGF) and its receptor (c-met) in human placenta: reduced HGF expression in intrauterine growth restriction","volume":"153","author":"Somerset","year":"1998","journal-title":"Am. J. Pathol."},{"issue":"6892","key":"10.1016\/j.placenta.2024.06.010_bib116","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1038\/nature00819","article-title":"Placental-specific IGF-II is a major modulator of placental and fetal growth","volume":"417","author":"Const\u00e2ncia","year":"2002","journal-title":"Nature"},{"issue":"21","key":"10.1016\/j.placenta.2024.06.010_bib117","doi-asserted-by":"crossref","first-page":"8204","DOI":"10.1073\/pnas.0402508101","article-title":"Placental-specific insulin-like growth factor 2 (Igf2) regulates the diffusional exchange characteristics of the mouse placenta","volume":"101","author":"Sibley","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"4","key":"10.1016\/j.placenta.2024.06.010_bib118","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1093\/emboj\/18.4.934","article-title":"JunB is essential for mammalian placentation","volume":"18","author":"Schorpp-Kistner","year":"1999","journal-title":"EMBO J."},{"issue":"11","key":"10.1016\/j.placenta.2024.06.010_bib119","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1046\/j.1365-2443.2003.00680.x","article-title":"Essential role for ERK2 mitogen-activated protein kinase in placental development","volume":"8","author":"Hatano","year":"2003","journal-title":"Gene Cell."},{"issue":"1","key":"10.1016\/j.placenta.2024.06.010_bib120","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S1097-2765(05)00014-6","article-title":"Essential role of p38alpha MAP kinase in placental but not embryonic cardiovascular development","volume":"6","author":"Adams","year":"2000","journal-title":"Mol. Cell"},{"issue":"19","key":"10.1016\/j.placenta.2024.06.010_bib121","doi-asserted-by":"crossref","first-page":"10454","DOI":"10.1073\/pnas.180316397","article-title":"Essential role for p38alpha mitogen-activated protein kinase in placental angiogenesis","volume":"97","author":"Mudgett","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"11","key":"10.1016\/j.placenta.2024.06.010_bib122","doi-asserted-by":"crossref","first-page":"2235","DOI":"10.1242\/dev.059105","article-title":"p45NF-E2 represses Gcm1 in trophoblast cells to regulate syncytium formation, placental vascularization and embryonic growth","volume":"138","author":"Kashif","year":"2011","journal-title":"Development"},{"issue":"11","key":"10.1016\/j.placenta.2024.06.010_bib123","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1101\/gad.14.11.1343","article-title":"Notch signaling is essential for vascular morphogenesis in mice","volume":"14","author":"Krebs","year":"2000","journal-title":"Genes Dev."},{"issue":"3","key":"10.1016\/j.placenta.2024.06.010_bib124","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.acthis.2009.10.006","article-title":"Distribution of Notch family proteins in intrauterine growth restriction and hypertension complicated human term placentas","volume":"113","author":"Sahin","year":"2011","journal-title":"Acta Histochem."},{"issue":"3","key":"10.1016\/j.placenta.2024.06.010_bib125","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1111\/j.1432-0436.2006.00137.x","article-title":"Notch2 is required for formation of the placental circulatory system, but not for cell-type specification in the developing mouse placenta","volume":"75","author":"Hamada","year":"2007","journal-title":"Differentiation"},{"issue":"10","key":"10.1016\/j.placenta.2024.06.010_bib126","doi-asserted-by":"crossref","first-page":"2276","DOI":"10.1161\/ATVBAHA.114.303693","article-title":"Gestational loss and growth restriction by angiogenic defects in placental growth factor transgenic mice","volume":"34","author":"Kang","year":"2014","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"3","key":"10.1016\/j.placenta.2024.06.010_bib127","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1053\/j.semperi.2008.02.006","article-title":"Vasculogenesis and angiogenesis in the IUGR placenta","volume":"32","author":"Arroyo","year":"2008","journal-title":"Semin. Perinatol."},{"issue":"4","key":"10.1016\/j.placenta.2024.06.010_bib128","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/S1097-2765(00)80209-9","article-title":"PPAR gamma is required for placental, cardiac, and adipose tissue development","volume":"4","author":"Barak","year":"1999","journal-title":"Mol. Cell"},{"issue":"11","key":"10.1016\/j.placenta.2024.06.010_bib129","doi-asserted-by":"crossref","first-page":"e8055","DOI":"10.1371\/journal.pone.0008055","article-title":"PPARgamma regulates trophoblast proliferation and promotes labyrinthine trilineage differentiation","volume":"4","author":"Parast","year":"2009","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.placenta.2024.06.010_bib130","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.placenta.2008.11.013","article-title":"Peroxisome proliferator-activated receptors and retinoid X receptor-alpha in term human gestational tissues: tissue specific and labour-associated changes","volume":"30","author":"Holdsworth-Carson","year":"2009","journal-title":"Placenta"},{"issue":"3","key":"10.1016\/j.placenta.2024.06.010_bib131","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.placenta.2009.12.009","article-title":"Peroxisome proliferator-activated receptors are altered in pathologies of the human placenta: gestational diabetes mellitus, intrauterine growth restriction and preeclampsia","volume":"31","author":"Holdsworth-Carson","year":"2010","journal-title":"Placenta"},{"issue":"6926","key":"10.1016\/j.placenta.2024.06.010_bib132","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1038\/nature01417","article-title":"Extra-embryonic function of Rb is essential for embryonic development and viability","volume":"421","author":"Wu","year":"2003","journal-title":"Nature"},{"issue":"2","key":"10.1016\/j.placenta.2024.06.010_bib133","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1242\/dev.121.2.489","article-title":"Defective development of the embryonic and extraembryonic circulatory systems in vascular cell adhesion molecule (VCAM-1) deficient mice","volume":"121","author":"Kwee","year":"1995","journal-title":"Development"},{"issue":"1","key":"10.1016\/j.placenta.2024.06.010_bib134","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1101\/gad.9.1.1","article-title":"Targeted disruption of the murine VCAM1 gene: essential role of VCAM-1 in chorioallantoic fusion and placentation","volume":"9","author":"Gurtner","year":"1995","journal-title":"Genes Dev."},{"issue":"4","key":"10.1016\/j.placenta.2024.06.010_bib135","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1111\/j.1600-0897.1997.tb00518.x","article-title":"Expression of cell adhesion molecules in the extravillous trophoblast is altered in IUGR","volume":"38","author":"Zygmunt","year":"1997","journal-title":"Am. J. Reprod. Immunol."},{"issue":"6573","key":"10.1016\/j.placenta.2024.06.010_bib136","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1038\/380435a0","article-title":"Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele","volume":"380","author":"Carmeliet","year":"1996","journal-title":"Nature"},{"issue":"6573","key":"10.1016\/j.placenta.2024.06.010_bib137","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1038\/380439a0","article-title":"Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene","volume":"380","author":"Ferrara","year":"1996","journal-title":"Nature"},{"issue":"4","key":"10.1016\/j.placenta.2024.06.010_bib138","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/S0143-4004(97)80061-6","article-title":"Placental expression of vascular endothelial growth factor in placentae from pregnancies complicated by pre-eclampsia and intrauterine growth restriction does not support placental hypoxia at delivery","volume":"18","author":"Lyall","year":"1997","journal-title":"Placenta"},{"issue":"10","key":"10.1016\/j.placenta.2024.06.010_bib139","doi-asserted-by":"crossref","first-page":"984","DOI":"10.3109\/14767058.2013.766702","article-title":"Gene expression patterns of vascular endothelial growth factor (VEGF-A) in human placenta from pregnancies with intrauterine growth restriction","volume":"26","author":"Szentpeteri","year":"2013","journal-title":"J. Matern. Fetal Neonatal Med."},{"issue":"11","key":"10.1016\/j.placenta.2024.06.010_bib140","doi-asserted-by":"crossref","first-page":"3343","DOI":"10.1242\/dev.122.11.3343","article-title":"Targeted disruption of the Wnt2 gene results in placentation defects","volume":"122","author":"Monkley","year":"1996","journal-title":"Development"},{"issue":"1","key":"10.1016\/j.placenta.2024.06.010_bib141","doi-asserted-by":"crossref","first-page":"33","DOI":"10.2217\/epi.15.101","article-title":"Fetal growth restriction and methylation of growth-related genes in the placenta","volume":"8","author":"Xiao","year":"2016","journal-title":"Epigenomics"}],"container-title":["Placenta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400424002844?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400424002844?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T18:12:49Z","timestamp":1777486369000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0143400424002844"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":141,"alternative-id":["S0143400424002844"],"URL":"https:\/\/doi.org\/10.1016\/j.placenta.2024.06.010","relation":{},"ISSN":["0143-4004"],"issn-type":[{"value":"0143-4004","type":"print"}],"subject":[],"published":{"date-parts":[[2024,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Homeobox genes in the human placenta: Twists and turns on the path to find novel targets","name":"articletitle","label":"Article Title"},{"value":"Placenta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.placenta.2024.06.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}