{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T05:34:32Z","timestamp":1783488872593,"version":"3.55.0"},"reference-count":19,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T00:00:00Z","timestamp":1780704000000},"content-version":"am","delay-in-days":370,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["RR020141-01"],"award-info":[{"award-number":["RR020141-01"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["RR15459-01"],"award-info":[{"award-number":["RR15459-01"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P51OD11106"],"award-info":[{"award-number":["P51OD11106"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000071","name":"National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["R01HD113327"],"award-info":[{"award-number":["R01HD113327"]}],"id":[{"id":"10.13039\/100000071","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000071","name":"National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["R01HD090657"],"award-info":[{"award-number":["R01HD090657"]}],"id":[{"id":"10.13039\/100000071","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Placenta"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.placenta.2024.09.013","type":"journal-article","created":{"date-parts":[[2024,9,20]],"date-time":"2024-09-20T11:51:00Z","timestamp":1726833060000},"page":"103-108","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Nanoparticle-mediated delivery of placental gene therapy via uterine artery catheterization in a pregnant rhesus macaque"],"prefix":"10.1016","volume":"166","author":[{"given":"Jenna K.","family":"Schmidt","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca L.","family":"Wilson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baylea N.","family":"Davenport","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy A.","family":"Hacker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Casey","family":"Fitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather A.","family":"Simmons","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele L.","family":"Schotzko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thaddeus G.","family":"Golos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7356-8420","authenticated-orcid":false,"given":"Helen N.","family":"Jones","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.placenta.2024.09.013_bib1","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.ajog.2010.08.009","article-title":"The \"Great Obstetrical Syndromes\" are associated with disorders of deep placentation","volume":"204","author":"Brosens","year":"2011","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.placenta.2024.09.013_bib2","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.placenta.2017.06.009","article-title":"Child neurodevelopmental outcomes following preterm and term birth: what can the placenta tell us?","volume":"57","author":"Hodyl","year":"2017","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2024.09.013_bib3","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1111\/j.1479-828X.2006.00506.x","article-title":"The developmental origins of adult disease (Barker) hypothesis","volume":"46","author":"De Boo","year":"2006","journal-title":"Aust. N. Z. J. Obstet. Gynaecol."},{"key":"10.1016\/j.placenta.2024.09.013_bib4","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1159\/000273066","article-title":"Developmental origins of adult disease","volume":"19","author":"Langley-Evans","year":"2010","journal-title":"Med. Princ. Pract. : international journal of the Kuwait University, Health Science Centre"},{"key":"10.1016\/j.placenta.2024.09.013_bib5","doi-asserted-by":"crossref","first-page":"588S","DOI":"10.1080\/07315724.2004.10719428","article-title":"The developmental origins of adult disease","volume":"23","author":"Barker","year":"2004","journal-title":"J. Am. Coll. Nutr."},{"key":"10.1016\/j.placenta.2024.09.013_bib6","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0140879","article-title":"Development of non-viral, trophoblast-specific gene delivery for placental therapy","volume":"10","author":"Abd Ellah","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.placenta.2024.09.013_bib7","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2022.1055234","article-title":"Placental treatment with insulin-like growth factor 1 via nanoparticle differentially impacts vascular remodeling factors in Guinea pig sub-placenta\/decidua","volume":"13","author":"Davenport","year":"2023","journal-title":"Front. Physiol."},{"key":"10.1016\/j.placenta.2024.09.013_bib8","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1002\/mrd.23644","article-title":"Nanoparticle-mediated transgene expression of insulin-like growth factor 1 in the growth restricted Guinea pig placenta increases placenta nutrient transporter expression and fetal glucose concentrations","volume":"89","author":"Wilson","year":"2022","journal-title":"Mol. Reprod. Dev."},{"key":"10.1016\/j.placenta.2024.09.013_bib9","doi-asserted-by":"crossref","first-page":"R653","DOI":"10.1152\/ajpregu.00250.2020","article-title":"Insulin-like growth factor 1 signaling in the placenta requires endothelial nitric oxide synthase to support trophoblast function and normal fetal growth","volume":"320","author":"Wilson","year":"2021","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.placenta.2024.09.013_bib10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.placenta.2020.02.006","article-title":"Nanoparticle mediated increased insulin-like growth factor 1 expression enhances human placenta syncytium function","volume":"93","author":"Wilson","year":"2020","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2024.09.013_bib11","doi-asserted-by":"crossref","first-page":"5057","DOI":"10.1113\/JP273330","article-title":"Placental phenotype and the insulin-like growth factors: resource allocation to fetal growth","volume":"595","author":"Sferruzzi-Perri","year":"2017","journal-title":"J. Physiol."},{"key":"10.1016\/j.placenta.2024.09.013_bib12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1677\/JOE-10-0174","article-title":"Maternal growth factor regulation of human placental development and fetal growth","volume":"207","author":"Forbes","year":"2010","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.placenta.2024.09.013_bib13","doi-asserted-by":"crossref","first-page":"108S","DOI":"10.1177\/0192623308326095","article-title":"The macaque placenta-A mini-review","volume":"36","author":"de Rijk","year":"2008","journal-title":"Toxicol. Pathol."},{"key":"10.1016\/j.placenta.2024.09.013_bib14","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1006378","article-title":"Highly efficient maternal-fetal Zika virus transmission in pregnant rhesus macaques","volume":"13","author":"Nguyen","year":"2017","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.placenta.2024.09.013_bib15","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1011274","article-title":"Vertical transmission of African-lineage Zika virus through the fetal membranes in a rhesus macaque (Macaca mulatta) model","volume":"19","author":"Koenig","year":"2023","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.placenta.2024.09.013_bib16","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(T)(-Delta Delta C) method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.placenta.2024.09.013_bib17","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1002\/ajp.1350150405","article-title":"Prenatal growth in the cynomolgus and rhesus macaque (Macaca fascicularis and Macaca mulatta): a comparison by ultrasonography","volume":"15","author":"Tarantal","year":"1988","journal-title":"Am. J. Primatol."},{"key":"10.1016\/j.placenta.2024.09.013_bib18","doi-asserted-by":"crossref","DOI":"10.1002\/ajp.23526","article-title":"Rhesus macaque fetal and placental growth demographics: a resource for laboratory animal researchers","volume":"85","author":"Roberts","year":"2023","journal-title":"Am. J. Primatol."},{"key":"10.1016\/j.placenta.2024.09.013_bib19","article-title":"Molecular actions of heparin and their implications in preventing pre-eclampsia","volume":"JTH","author":"Wat","year":"2018","journal-title":"J. Thromb. Haemostasis"}],"container-title":["Placenta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400424006568?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400424006568?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T07:56:46Z","timestamp":1762243006000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0143400424006568"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":19,"alternative-id":["S0143400424006568"],"URL":"https:\/\/doi.org\/10.1016\/j.placenta.2024.09.013","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2024.04.10.588902","asserted-by":"object"}]},"ISSN":["0143-4004"],"issn-type":[{"value":"0143-4004","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Nanoparticle-mediated delivery of placental gene therapy via uterine artery catheterization in a pregnant rhesus macaque","name":"articletitle","label":"Article Title"},{"value":"Placenta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.placenta.2024.09.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}