{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T01:40:33Z","timestamp":1790991633406,"version":"4.1.0"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Placenta"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.placenta.2024.10.013","type":"journal-article","created":{"date-parts":[[2024,10,22]],"date-time":"2024-10-22T03:26:40Z","timestamp":1729567600000},"page":"145-155","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Puerarin alleviates symptoms of preeclampsia through the repression of trophoblast ferroptosis via the CREB\/HO-1 pathway"],"prefix":"10.1016","volume":"158","author":[{"given":"Xiaojing","family":"Yue","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Menglan","family":"Pang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhixing","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruisi","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiqiang","family":"Zha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liping","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.placenta.2024.10.013_bib1","doi-asserted-by":"crossref","first-page":"543","DOI":"10.2215\/CJN.03761106","article-title":"Pathophysiology of the clinical manifestations of preeclampsia","volume":"2","author":"Hladunewich","year":"2007","journal-title":"Clin. J. Am. Soc. Nephrol."},{"issue":"9741","key":"10.1016\/j.placenta.2024.10.013_bib2","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/S0140-6736(10)60279-6","article-title":"Pre-eclampsia","volume":"376","author":"Steegers","year":"2010","journal-title":"Lancet"},{"issue":"8","key":"10.1016\/j.placenta.2024.10.013_bib3","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1038\/nrneph.2014.102","article-title":"Pre-eclampsia part 1: current understanding of its pathophysiology","volume":"10","author":"Chaiworapongsa","year":"2014","journal-title":"Nat. Rev. Nephrol."},{"issue":"3","key":"10.1016\/j.placenta.2024.10.013_bib4","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1136\/gutjnl-2019-319101","article-title":"Gut dysbiosis induces the development of pre-eclampsia through bacterial translocation","volume":"69","author":"Chen","year":"2020","journal-title":"Gut"},{"issue":"1","key":"10.1016\/j.placenta.2024.10.013_bib5","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1186\/s12884-022-04423-6","article-title":"Expression profiles and functions of ferroptosis-related genes in the placental tissue samples of early- and late-onset preeclampsia patients","volume":"22","author":"Yang","year":"2022","journal-title":"BMC Pregnancy Childbirth"},{"key":"10.1016\/j.placenta.2024.10.013_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2019.101402","article-title":"miR-30-5p-mediated ferroptosis of trophoblasts is implicated in the pathogenesis of preeclampsia","volume":"29","author":"Zhang","year":"2020","journal-title":"Redox Biol."},{"key":"10.1016\/j.placenta.2024.10.013_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2022.102555","article-title":"Ferritin light chain deficiency-induced ferroptosis is involved in preeclampsia pathophysiology by disturbing uterine spiral artery remodelling","volume":"58","author":"Yang","year":"2022","journal-title":"Redox Biol."},{"issue":"44","key":"10.1016\/j.placenta.2024.10.013_bib8","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000031583","article-title":"Identification of ferroptosis-related genes in syncytiotrophoblast-derived extracellular vesicles of preeclampsia","volume":"101","author":"Wu","year":"2022","journal-title":"Medicine"},{"issue":"2","key":"10.1016\/j.placenta.2024.10.013_bib9","first-page":"273","article-title":"Ferroptosis: a regulated cell death nexus linking metabolism","volume":"171","author":"Stockwell","year":"2017","journal-title":"redox biology, and disease, Cell"},{"key":"10.1016\/j.placenta.2024.10.013_bib10","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.placenta.2021.03.007","article-title":"Ferroptosis, trophoblast lipotoxic damage, and adverse pregnancy outcome","volume":"108","author":"Beharier","year":"2021","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2024.10.013_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2022.102555","article-title":"Ferritin light chain deficiency-induced ferroptosis is involved in preeclampsia pathophysiology by disturbing uterine spiral artery remodelling","volume":"58","author":"Yang","year":"2022","journal-title":"Redox Biol."},{"key":"10.1016\/j.placenta.2024.10.013_bib12","doi-asserted-by":"crossref","DOI":"10.1038\/srep33300","article-title":"Evaluation of glutathione peroxidase 4 role in preeclampsia","volume":"6","author":"Peng","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.placenta.2024.10.013_bib13","doi-asserted-by":"crossref","DOI":"10.1155\/2020\/4683798","article-title":"Haplotype analysis of candidate genes involved in inflammation and oxidative stress and the susceptibility to preeclampsia","volume":"2020","author":"Chen","year":"2020","journal-title":"J Immunol Res"},{"issue":"2","key":"10.1016\/j.placenta.2024.10.013_bib14","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1007\/s12011-015-0545-7","article-title":"Selenium and preeclampsia: a systematic review and meta-analysis","volume":"171","author":"Xu","year":"2016","journal-title":"Biol. Trace Elem. Res."},{"issue":"11","key":"10.1016\/j.placenta.2024.10.013_bib15","doi-asserted-by":"crossref","first-page":"2703","DOI":"10.7150\/ijbs.59404","article-title":"Tagitinin C induces ferroptosis through PERK-Nrf2-HO-1 signaling pathway in colorectal cancer cells","volume":"17","author":"Wei","year":"2021","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.placenta.2024.10.013_bib16","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.imlet.2020.06.005","article-title":"Ferroptosis mediated DSS-induced ulcerative colitis associated with Nrf2\/HO-1 signaling pathway","volume":"225","author":"Chen","year":"2020","journal-title":"Immunol. Lett."},{"issue":"7","key":"10.1016\/j.placenta.2024.10.013_bib17","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1002\/ptr.5083","article-title":"Puerarin: a review of pharmacological effects","volume":"28","author":"Zhou","year":"2014","journal-title":"Phytother Res."},{"key":"10.1016\/j.placenta.2024.10.013_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2020.110734","article-title":"A comprehensive review on Pueraria: insights on its chemistry and medicinal value","volume":"131","author":"Wang","year":"2020","journal-title":"Biomed. Pharmacother."},{"issue":"8","key":"10.1016\/j.placenta.2024.10.013_bib19","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1002\/jcph.96","article-title":"Radix Puerariae: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use","volume":"53","author":"Zhang","year":"2013","journal-title":"J. Clin. Pharmacol."},{"issue":"23","key":"10.1016\/j.placenta.2024.10.013_bib20","doi-asserted-by":"crossref","DOI":"10.3390\/nu14235025","article-title":"Puerariae lobatae radix alleviates pre-eclampsia by remodeling gut microbiota and protecting the gut and placental barriers","volume":"14","author":"Huang","year":"2022","journal-title":"Nutrients"},{"issue":"6","key":"10.1016\/j.placenta.2024.10.013_bib21","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1007\/s00210-008-0388-2","article-title":"Analysis of the mechanisms underlying the endothelium-dependent antivasoconstriction of puerarin in rat aorta","volume":"379","author":"Yan","year":"2009","journal-title":"Naunyn-Schmiedeberg\u2019s Arch. Pharmacol."},{"issue":"3\u20134","key":"10.1016\/j.placenta.2024.10.013_bib22","first-page":"373","article-title":"The effect of puerarin on serum nitric oxide concentration and myocardial eNOS expression in rats with myocardial infarction","volume":"10","author":"Zhang","year":"2008","journal-title":"J. Asian Nat. Prod. Res."},{"issue":"4","key":"10.1016\/j.placenta.2024.10.013_bib23","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1179\/174313209X444017","article-title":"Puerarin protects against ischemic brain injury in a rat model of transient focal ischemia","volume":"31","author":"Gao","year":"2009","journal-title":"Neurol. Res."},{"issue":"1\u20133","key":"10.1016\/j.placenta.2024.10.013_bib24","first-page":"1","article-title":"Puerarin protects rat pancreatic islets from damage by hydrogen peroxide","volume":"529","author":"Xiong","year":"2006","journal-title":"Eur. J. Pharmacol."},{"issue":"16","key":"10.1016\/j.placenta.2024.10.013_bib25","first-page":"2522","article-title":"Inducible nitric oxide synthase and Fas\/FasL with C3 expression of mouse retinal pigment epithelial cells in response to stimulation by peroxynitrite and antagonism of puerarin","volume":"124","author":"Hao","year":"2011","journal-title":"Chin Med J (Engl)"},{"issue":"8","key":"10.1016\/j.placenta.2024.10.013_bib26","doi-asserted-by":"crossref","first-page":"3617","DOI":"10.18632\/aging.204033","article-title":"Puerarin protects against sepsis-induced myocardial injury through AMPK-mediated ferroptosis signaling","volume":"14","author":"Zhou","year":"2022","journal-title":"Aging (Albany NY)"},{"key":"10.1016\/j.placenta.2024.10.013_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2022.113403","article-title":"Puerarin activates adaptive autophagy and protects the myocardium against doxorubicin-induced cardiotoxicity via the 14-3-3gamma\/PKCepsilon pathway","volume":"153","author":"Peng","year":"2022","journal-title":"Biomed. Pharmacother."},{"issue":"1","key":"10.1016\/j.placenta.2024.10.013_bib28","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.bbrc.2018.02.061","article-title":"Puerarin protects against heart failure induced by pressure overload through mitigation of ferroptosis","volume":"497","author":"Liu","year":"2018","journal-title":"Biochem Bioph Res Co"},{"key":"10.1016\/j.placenta.2024.10.013_bib29","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2021.664766","article-title":"Collagen I induces preeclampsia-like symptoms by suppressing proliferation and invasion of trophoblasts","volume":"12","author":"Feng","year":"2021","journal-title":"Front. Endocrinol."},{"issue":"2","key":"10.1016\/j.placenta.2024.10.013_bib30","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/0301-2115(95)02106-H","article-title":"Pre-eclampsia: physiology and immunological aspects","volume":"61","author":"Vinatier","year":"1995","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"key":"10.1016\/j.placenta.2024.10.013_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2021.108001","article-title":"The natural compound puerarin alleviates inflammation and apoptosis in experimental cell and rat preeclampsia models","volume":"99","author":"Liang","year":"2021","journal-title":"Int. Immunopharm."},{"issue":"2","key":"10.1016\/j.placenta.2024.10.013_bib32","doi-asserted-by":"crossref","DOI":"10.1111\/aji.13510","article-title":"Puerarin attenuates preeclampsia-induced trophoblast mobility loss and inflammation by modulating miR-181b-5p\/RBAK axis","volume":"87","author":"Guo","year":"2022","journal-title":"Am. J. Reprod. Immunol."},{"key":"10.1016\/j.placenta.2024.10.013_bib33","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.placenta.2022.06.015","article-title":"Puerarin protects against H(2)O(2)-induced apoptosis of HTR-8\/SVneo cells by regulating the miR-20a-5p\/VEGFA\/Akt axis","volume":"126","author":"He","year":"2022","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2024.10.013_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2023.115466","article-title":"Impact of ferroptosis on preeclampsia: a review","volume":"167","author":"Shan","year":"2023","journal-title":"Biomed. Pharmacother."},{"issue":"1","key":"10.1016\/j.placenta.2024.10.013_bib35","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/s00404-012-2502-4","article-title":"Trace elements and oxidative stress in hypertensive disorders of pregnancy","volume":"287","author":"Fenzl","year":"2013","journal-title":"Arch. Gynecol. Obstet."},{"issue":"1","key":"10.1016\/j.placenta.2024.10.013_bib36","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1080\/01443615.2018.1450368","article-title":"Increased serum iron levels in pregnant women with preeclampsia: a meta-analysis of observational studies","volume":"39","author":"Liu","year":"2019","journal-title":"J. Obstet. Gynaecol."},{"issue":"1\u20132","key":"10.1016\/j.placenta.2024.10.013_bib37","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/s11010-008-9739-z","article-title":"Alterations in lipid peroxidation and antioxidant status in pregnancy with preeclampsia","volume":"313","author":"Kaur","year":"2008","journal-title":"Mol. Cell. Biochem."},{"issue":"3","key":"10.1016\/j.placenta.2024.10.013_bib38","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.ijgo.2006.10.011","article-title":"Antioxidant enzyme activities and lipid peroxidation in preeclampsia","volume":"96","author":"Biri","year":"2007","journal-title":"Int. J. Gynaecol. Obstet."},{"issue":"16","key":"10.1016\/j.placenta.2024.10.013_bib39","doi-asserted-by":"crossref","DOI":"10.3390\/ijms23169395","article-title":"Iron metabolism and ferroptosis in physiological and pathological pregnancy","volume":"23","author":"Zhang","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.placenta.2024.10.013_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.abb.2019.108073","article-title":"HO-1 overexpression and underexpression: clinical implications","volume":"673","author":"Drummond","year":"2019","journal-title":"Arch. Biochem. Biophys."},{"issue":"5","key":"10.1016\/j.placenta.2024.10.013_bib41","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1093\/humupd\/dmaa014","article-title":"Haem oxygenases play a pivotal role in placental physiology and pathology","volume":"26","author":"Peoc'h","year":"2020","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.placenta.2024.10.013_bib42","doi-asserted-by":"crossref","DOI":"10.1155\/2018\/6035868","article-title":"Circulating heme oxygenase-1: not a predictor of preeclampsia but highly expressed in pregnant women who subsequently develop severe preeclampsia","volume":"2018","author":"Sandrim","year":"2018","journal-title":"Oxid. Med. Cell. Longev."},{"issue":"4","key":"10.1016\/j.placenta.2024.10.013_bib43","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1016\/j.transci.2018.05.028","article-title":"Haemin-induced cell death in human monocytic cells is consistent with ferroptosis","volume":"57","author":"Imoto","year":"2018","journal-title":"Transfus. Apher. Sci."},{"issue":"7","key":"10.1016\/j.placenta.2024.10.013_bib44","doi-asserted-by":"crossref","first-page":"3329","DOI":"10.1007\/s10571-023-01388-8","article-title":"The mechanisms of ferroptosis under hypoxia","volume":"43","author":"Gao","year":"2023","journal-title":"Cell. Mol. Neurobiol."},{"key":"10.1016\/j.placenta.2024.10.013_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2021.101971","article-title":"HO-1-mediated ferroptosis as a target for protection against retinal pigment epithelium degeneration","volume":"43","author":"Tang","year":"2021","journal-title":"Redox Biol."},{"key":"10.1016\/j.placenta.2024.10.013_bib46","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/3846217","article-title":"HO-1 contributes to luteolin-triggered ferroptosis in clear cell renal cell carcinoma via increasing the labile iron pool and promoting lipid peroxidation","volume":"2022","author":"Han","year":"2022","journal-title":"Oxid. Med. Cell. Longev."},{"issue":"6","key":"10.1016\/j.placenta.2024.10.013_bib47","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1182\/blood.2020008455","article-title":"Excess heme upregulates heme oxygenase 1 and promotes cardiac ferroptosis in mice with sickle cell disease","volume":"139","author":"Menon","year":"2022","journal-title":"Blood"},{"key":"10.1016\/j.placenta.2024.10.013_bib48","article-title":"Maresin1 protect against ferroptosis-induced liver injury through ROS inhibition and Nrf2\/HO-1\/GPX4 activation","volume":"13","author":"Yang","year":"2022","journal-title":"Front. Pharmacol."},{"issue":"11","key":"10.1016\/j.placenta.2024.10.013_bib49","doi-asserted-by":"crossref","first-page":"2966","DOI":"10.1002\/2211-5463.13276","article-title":"Icariin inhibits hypoxia\/reoxygenation-induced ferroptosis of cardiomyocytes via regulation of the Nrf2\/HO-1 signaling pathway","volume":"11","author":"Liu","year":"2021","journal-title":"FEBS Open Bio"},{"issue":"11","key":"10.1016\/j.placenta.2024.10.013_bib50","doi-asserted-by":"crossref","first-page":"3797","DOI":"10.1111\/jog.15009","article-title":"Activation of Nrf2 signaling protects hypoxia-induced HTR-8\/SVneo cells against ferroptosis","volume":"47","author":"Wang","year":"2021","journal-title":"J. Obstet. Gynaecol. Res."},{"issue":"14","key":"10.1016\/j.placenta.2024.10.013_bib51","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1089\/ars.2019.7991","article-title":"Regulation of the expression of heme oxygenase-1: signal transduction, gene promoter activation, and beyond","volume":"32","author":"Medina","year":"2020","journal-title":"Antioxidants Redox Signal."},{"issue":"2","key":"10.1016\/j.placenta.2024.10.013_bib52","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1530\/JME-16-0005","article-title":"Role of CREB on heme oxygenase-1 induction in adrenal cells: involvement of the PI3K pathway","volume":"57","author":"Astort","year":"2016","journal-title":"J. Mol. Endocrinol."},{"key":"10.1016\/j.placenta.2024.10.013_bib53","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.molimm.2017.08.006","article-title":"Glutaredoxin 1 (GRX1) inhibits oxidative stress and apoptosis of chondrocytes by regulating CREB\/HO-1 in osteoarthritis","volume":"90","author":"Sun","year":"2017","journal-title":"Mol. Immunol."},{"issue":"4","key":"10.1016\/j.placenta.2024.10.013_bib54","doi-asserted-by":"crossref","DOI":"10.3390\/antiox11040649","article-title":"Menthae herba attenuates neuroinflammation by regulating CREB\/Nrf2\/HO-1 pathway in BV2 microglial cells","volume":"11","author":"Park","year":"2022","journal-title":"Antioxidants"},{"key":"10.1016\/j.placenta.2024.10.013_bib55","doi-asserted-by":"crossref","DOI":"10.1016\/j.neulet.2022.136754","article-title":"Melatonin mitigates traumatic brain injury-induced depression-like behaviors through HO-1\/CREB signal in rats","volume":"784","author":"Xie","year":"2022","journal-title":"Neurosci. Lett."}],"container-title":["Placenta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400424006854?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400424006854?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T08:24:40Z","timestamp":1733991880000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0143400424006854"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":55,"alternative-id":["S0143400424006854"],"URL":"https:\/\/doi.org\/10.1016\/j.placenta.2024.10.013","relation":{},"ISSN":["0143-4004"],"issn-type":[{"value":"0143-4004","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Puerarin alleviates symptoms of preeclampsia through the repression of trophoblast ferroptosis via the CREB\/HO-1 pathway","name":"articletitle","label":"Article Title"},{"value":"Placenta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.placenta.2024.10.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}