{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,8]],"date-time":"2026-08-08T21:03:21Z","timestamp":1786223001042,"version":"build-2736575974"},"reference-count":60,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology of the People's Republic of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001407","name":"India Ministry of Science & Technology Department of Biotechnology","doi-asserted-by":"publisher","award":["BT \/PR22491\/MED\/97\/361\/2016"],"award-info":[{"award-number":["BT \/PR22491\/MED\/97\/361\/2016"]}],"id":[{"id":"10.13039\/501100001407","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Placenta"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.placenta.2024.10.019","type":"journal-article","created":{"date-parts":[[2024,10,24]],"date-time":"2024-10-24T02:49:52Z","timestamp":1729738192000},"page":"206-215","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Methylation and expression of imprinted genes in circulating extracellular vesicles from women experiencing early onset preeclampsia"],"prefix":"10.1016","volume":"158","author":[{"given":"Uma","family":"Shinde","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kushaan","family":"Khambata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanketa","family":"Raut","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aishwarya","family":"Rao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vandana","family":"Bansal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niranjan","family":"Mayadeo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dhanjit kumar","family":"Das","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taruna","family":"Madan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5610-0770","authenticated-orcid":false,"given":"Vinoth","family":"Prasanna Gunasekaran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9937-7518","authenticated-orcid":false,"given":"Nafisa Huseni","family":"Balasinor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.placenta.2024.10.019_bib1","doi-asserted-by":"crossref","first-page":"e237","DOI":"10.1097\/AOG.0000000000003891","volume":"135","year":"2020","journal-title":"Obstet. Gynecol."},{"issue":"5","key":"10.1016\/j.placenta.2024.10.019_bib2","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/j.jogc.2022.02.010","volume":"44","author":"Chari","year":"2022","journal-title":"J. Obstet. Gynaecol. Can."},{"issue":"7","key":"10.1016\/j.placenta.2024.10.019_bib3","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1161\/CIRCRESAHA.118.313276","article-title":"Preeclampsia: pathophysiology, challenges, and perspectives","volume":"124","author":"Rana","year":"2019","journal-title":"Circ. Res."},{"issue":"10297","key":"10.1016\/j.placenta.2024.10.019_bib4","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/S0140-6736(20)32335-7","article-title":"Pre-eclampsia","volume":"398","author":"Chappell","year":"2021","journal-title":"Lancet (London, England)"},{"key":"10.1016\/j.placenta.2024.10.019_bib5","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.preghy.2018.10.011","article-title":"Preeclampsia: disease biology and burden, its management strategies with reference to India","volume":"15","author":"Malik","year":"2019","journal-title":"Pregnancy hyperten."},{"issue":"2","key":"10.1016\/j.placenta.2024.10.019_bib6","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.gocm.2023.01.002","article-title":"Prevalence of hypertensive disorders of pregnancy, associated factors and pregnancy complications in a primigravida population","volume":"3","author":"Mathew","year":"2023","journal-title":"Gynecol. Obstet. Clini. Medi."},{"issue":"5","key":"10.1016\/j.placenta.2024.10.019_bib7","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1038\/s41581-019-0119-6","article-title":"Pre-eclampsia: pathogenesis, novel diagnostics and therapies","volume":"15","author":"Phipps","year":"2019","journal-title":"Nat. Rev. Nephrol."},{"issue":"6","key":"10.1016\/j.placenta.2024.10.019_bib8","doi-asserted-by":"crossref","first-page":"953","DOI":"10.3390\/biom10060953","article-title":"Pathogenesis of preeclampsia and therapeutic approaches targeting the placenta","volume":"10","author":"Jena","year":"2020","journal-title":"Biomolecules"},{"issue":"8","key":"10.1016\/j.placenta.2024.10.019_bib9","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1177\/1933719118766265","article-title":"Placental defects: an epigenetic perspective","volume":"25","author":"Deshpande","year":"2018","journal-title":"Reprod. Sci."},{"issue":"1","key":"10.1016\/j.placenta.2024.10.019_bib10","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1186\/s13148-019-0630-4","article-title":"Differences in expression rather than methylation at placenta-specific imprinted loci is associated with intrauterine growth restriction","volume":"11","author":"Monteagudo-S\u00e1nchez","year":"2019","journal-title":"Clin. Epigenet."},{"issue":"6","key":"10.1016\/j.placenta.2024.10.019_bib11","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1161\/HYPERTENSIONAHA.116.08261","article-title":"Associations between fetal imprinted genes and maternal blood pressure in pregnancy","volume":"68","author":"Petry","year":"2016","journal-title":"Hypertension"},{"issue":"12","key":"10.1016\/j.placenta.2024.10.019_bib12","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1093\/molehr\/8.12.1129","article-title":"Deficiency in p57Kip2 expression induces preeclampsia-like symptoms in mice","volume":"8","author":"Kanayama","year":"2002","journal-title":"Mol. Hum. Reprod."},{"issue":"6","key":"10.1016\/j.placenta.2024.10.019_bib13","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/j.acthis.2011.11.003","article-title":"Elevated expression of PEG10 in human placentas from preeclamptic pregnancies","volume":"114","author":"Chen","year":"2012","journal-title":"Acta Histochem."},{"issue":"4","key":"10.1016\/j.placenta.2024.10.019_bib14","doi-asserted-by":"crossref","first-page":"10607","DOI":"10.4238\/2014.December.18.2","article-title":"Expression and significance of the imprinted gene PEG10 in placenta of patients with preeclampsia","volume":"13","author":"Liang","year":"2014","journal-title":"Genet. Mol. Res.: GMR"},{"key":"10.1016\/j.placenta.2024.10.019_bib15","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.placenta.2020.02.007","article-title":"Trophoblast lineage-specific differentiation and associated alterations in preeclampsia and fetal growth restriction","volume":"102","author":"Farah","year":"2020","journal-title":"Placenta"},{"issue":"1","key":"10.1016\/j.placenta.2024.10.019_bib16","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-021-97799-y","article-title":"Oxidative stress-induced impairment of trophoblast function causes preeclampsia through the unfolded protein response pathway","volume":"11","author":"Mukherjee","year":"2021","journal-title":"Sci. Rep."},{"issue":"5","key":"10.1016\/j.placenta.2024.10.019_bib17","doi-asserted-by":"crossref","first-page":"317","DOI":"10.14348\/molcells.2021.0211","article-title":"Trophoblast cell subtypes and dysfunction in the placenta of individuals with preeclampsia revealed by single-cell RNA sequencing","volume":"45","author":"Zhou","year":"2022","journal-title":"Mol. Cell."},{"issue":"4","key":"10.1016\/j.placenta.2024.10.019_bib18","doi-asserted-by":"crossref","first-page":"2158","DOI":"10.3390\/ijms22042158","article-title":"Human placenta exosomes: biogenesis, isolation, composition, and prospects for use in diagnostics","volume":"22","author":"Burkova","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.placenta.2024.10.019_bib19","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.837281","article-title":"Synergies of extracellular vesicles and microchimerism in promoting immunotolerance during pregnancy","volume":"13","author":"Murrieta-Coxca","year":"2022","journal-title":"Front. Immunol."},{"issue":"7","key":"10.1016\/j.placenta.2024.10.019_bib20","doi-asserted-by":"crossref","first-page":"727","DOI":"10.3390\/cells8070727","article-title":"Overview of extracellular vesicles, their origin, composition, purpose, and methods for exosome isolation and analysis","volume":"8","author":"Doyle","year":"2019","journal-title":"Cells"},{"issue":"4","key":"10.1016\/j.placenta.2024.10.019_bib21","doi-asserted-by":"crossref","first-page":"1542","DOI":"10.1172\/JCI66517","article-title":"BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression","volume":"123","author":"Roccaro","year":"2013","journal-title":"J. Clin. Invest."},{"issue":"Suppl A","key":"10.1016\/j.placenta.2024.10.019_bib22","doi-asserted-by":"crossref","first-page":"S73","DOI":"10.1016\/j.placenta.2007.11.016","article-title":"Circulating microparticles in normal pregnancy and pre-eclampsia","volume":"29","author":"Redman","year":"2008","journal-title":"Placenta"},{"issue":"6","key":"10.1016\/j.placenta.2024.10.019_bib23","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1002\/cyto.a.20886","article-title":"Flow cytometric analysis of circulating microparticles in plasma","volume":"77","author":"Orozco","year":"2010","journal-title":"Cytometry Part A : the journal of the International Society for Analytical Cytology"},{"issue":"6","key":"10.1016\/j.placenta.2024.10.019_bib24","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0098667","article-title":"A gestational profile of placental exosomes in maternal plasma and their effects on endothelial cell migration","volume":"9","author":"Salomon","year":"2014","journal-title":"PLoS One"},{"issue":"7","key":"10.1016\/j.placenta.2024.10.019_bib25","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1093\/neuonc\/noab012","article-title":"Genome-wide methylation profiling of glioblastoma cell-derived extracellular vesicle DNA allows tumor classification","volume":"23","author":"Maire","year":"2021","journal-title":"Neuro Oncol."},{"key":"10.1016\/j.placenta.2024.10.019_bib26","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.atherosclerosis.2022.06.1026","article-title":"De novo DNA methylation induced by circulating extracellular vesicles from acute coronary syndrome patients","volume":"354","author":"Schiano","year":"2022","journal-title":"Atherosclerosis"},{"issue":"6","key":"10.1016\/j.placenta.2024.10.019_bib27","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1038\/cr.2014.44","article-title":"Double-stranded DNA in exosomes: a novel biomarker in cancer detection","volume":"24","author":"Thakur","year":"2014","journal-title":"Cell Res."},{"issue":"4","key":"10.1016\/j.placenta.2024.10.019_bib28","doi-asserted-by":"crossref","DOI":"10.1002\/jev2.12206","article-title":"Analysis of extracellular vesicle DNA at the single-vesicle level by nano-flow cytometry","volume":"11","author":"Liu","year":"2022","journal-title":"J. Extracell. Vesicles"},{"issue":"1","key":"10.1016\/j.placenta.2024.10.019_bib29","doi-asserted-by":"crossref","DOI":"10.1080\/20013078.2018.1535750","article-title":"Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines","volume":"7","author":"Th\u00e9ry","year":"2018","journal-title":"J. Extracell. Vesicles"},{"issue":"4","key":"10.1016\/j.placenta.2024.10.019_bib30","doi-asserted-by":"crossref","DOI":"10.1530\/REP-23-0215","article-title":"Isolation of serum-derived placental\/amnio-chorionic extracellular vesicles across pregnancy by immunoaffinity using PLAP and HLA-G","volume":"167","author":"Shinde","year":"2024","journal-title":"Reproduction"},{"issue":"11","key":"10.1016\/j.placenta.2024.10.019_bib31","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1101\/gr.161600","article-title":"Novel imprinted DLK11\/GTL2 domain on human chromosome 14 contains motifs that mimic those implicated in IGF2\/H19 regulation","volume":"10","author":"Wylie","year":"2000","journal-title":"Genome Res."},{"issue":"3","key":"10.1016\/j.placenta.2024.10.019_bib32","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0060105","article-title":"Molecular and clinical studies in 138 Japanese patients with Silver-Russell syndrome","volume":"8","author":"Fuke","year":"2013","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.placenta.2024.10.019_bib33","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1038\/hdy.2014.54","article-title":"The specification of imprints in mammals","volume":"113","author":"Hanna","year":"2014","journal-title":"Heredity"},{"issue":"4","key":"10.1016\/j.placenta.2024.10.019_bib34","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/j.jhep.2017.05.019","article-title":"Dendritic cell-derived exosomes elicit tumor regression in autochthonous hepatocellular carcinoma mouse models","volume":"67","author":"Lu","year":"2017","journal-title":"J. Hepatol."},{"issue":"6","key":"10.1016\/j.placenta.2024.10.019_bib35","doi-asserted-by":"crossref","first-page":"F1315","DOI":"10.1152\/ajprenal.00071.2020","article-title":"Preeclampsia beyond pregnancy: long-term consequences for mother and child","volume":"318","author":"Turbeville","year":"2020","journal-title":"Am. J. Physiol. Ren. Physiol."},{"key":"10.1016\/j.placenta.2024.10.019_bib36","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1186\/1471-2164-6-111","article-title":"Hypoxia-activated genes from early placenta are elevated in preeclampsia, but not in Intra-Uterine Growth Retardation","volume":"6","author":"Vaiman","year":"2005","journal-title":"BMC Genom."},{"issue":"11","key":"10.1016\/j.placenta.2024.10.019_bib37","doi-asserted-by":"crossref","DOI":"10.1098\/rsbl.2017.0643","article-title":"Associations between imprinted gene expression in the placenta, human fetal growth and preeclampsia","volume":"13","author":"Christians","year":"2017","journal-title":"Biol. Lett."},{"issue":"10","key":"10.1016\/j.placenta.2024.10.019_bib38","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.3390\/genes11101146","article-title":"Differences in placental imprinted gene expression across preeclamptic and non-preeclamptic pregnancies","volume":"11","author":"Deyssenroth","year":"2020","journal-title":"Genes"},{"issue":"3","key":"10.1016\/j.placenta.2024.10.019_bib39","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0174514","article-title":"Oxygen tension regulates the miRNA profile and bioactivity of exosomes released from extravillous trophoblast cells - liquid biopsies for monitoring complications of pregnancy","volume":"12","author":"Truong","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.placenta.2024.10.019_bib40","doi-asserted-by":"crossref","first-page":"175","DOI":"10.3389\/fphar.2014.00175","article-title":"Extravillous trophoblast cells-derived exosomes promote vascular smooth muscle cell migration","volume":"5","author":"Salomon","year":"2014","journal-title":"Front. Pharmacol."},{"issue":"9","key":"10.1016\/j.placenta.2024.10.019_bib41","doi-asserted-by":"crossref","first-page":"3182","DOI":"10.1210\/jc.2017-00672","article-title":"Placental exosomes as early biomarker of preeclampsia: potential role of exosomal MicroRNAs across gestation","volume":"102","author":"Salomon","year":"2017","journal-title":"J. Clin. Endocrinol. Metabol."},{"key":"10.1016\/j.placenta.2024.10.019_bib42","doi-asserted-by":"crossref","first-page":"1681","DOI":"10.2147\/IJWH.S382836","article-title":"An investigation of exosome concentration and exosomal microRNA (miR-155 and miR-222) expression in pregnant women with gestational hypertension and preeclampsia","volume":"14","author":"Ntsethe","year":"2022","journal-title":"Int. J. Wom. Health"},{"issue":"2","key":"10.1016\/j.placenta.2024.10.019_bib43","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/0168-9525(91)90230-N","article-title":"Genomic imprinting in mammalian development: a parental tug-of-war","volume":"7","author":"Moore","year":"1991","journal-title":"Trends Genet. : TIG (Trends Genet.)"},{"issue":"26","key":"10.1016\/j.placenta.2024.10.019_bib44","doi-asserted-by":"crossref","first-page":"10705","DOI":"10.1073\/pnas.1308998110","article-title":"Paternally expressed genes predominate in the placenta","volume":"110","author":"Wang","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"1","key":"10.1016\/j.placenta.2024.10.019_bib45","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1038\/ng1699","article-title":"Deletion of PEG10, an imprinted gene acquired from a retrotransposon, causes early embryonic lethality","volume":"38","author":"Ono","year":"2006","journal-title":"Nat. Genet."},{"issue":"19","key":"10.1016\/j.placenta.2024.10.019_bib46","doi-asserted-by":"crossref","DOI":"10.1242\/dev.199564","article-title":"PEG10 viral aspartic protease domain is essential for the maintenance of fetal capillary structure in the mouse placenta","volume":"148","author":"Shiura","year":"2021","journal-title":"Development"},{"issue":"4","key":"10.1016\/j.placenta.2024.10.019_bib47","doi-asserted-by":"crossref","first-page":"10607","DOI":"10.4238\/2014.December.18.2","article-title":"Expression and significance of the imprinted gene PEG10 in placenta of patients with preeclampsia","volume":"13","author":"Liang","year":"2014","journal-title":"Genet. Mol. Res.\u202f: GMR"},{"key":"10.1016\/j.placenta.2024.10.019_bib48","doi-asserted-by":"crossref","DOI":"10.1038\/srep40774","article-title":"Epigenetic modifications at DMRs of placental genes are subjected to variations in normal gestation, pathological conditions and folate supplementation","volume":"7","author":"Rahat","year":"2017","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.placenta.2024.10.019_bib49","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1186\/s12958-023-01116-3","article-title":"Paternal Expressed Gene 10 (PEG10) is decreased in early-onset preeclampsia","volume":"21","author":"Baird","year":"2023","journal-title":"Reprod. Biol. Endocrinol.\u202f: RB Elektron."},{"issue":"1","key":"10.1016\/j.placenta.2024.10.019_bib50","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1186\/s13059-024-03265-z","article-title":"Disruption of maternal vascular remodeling by a fetal endoretrovirus-derived gene in preeclampsia","volume":"25","author":"Gong","year":"2024","journal-title":"Genome Biol."},{"issue":"12","key":"10.1016\/j.placenta.2024.10.019_bib51","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0083359","article-title":"PEG3 mutational effects on reproduction and placenta-specific gene families","volume":"8","author":"Kim","year":"2013","journal-title":"PLoS One"},{"issue":"10","key":"10.1016\/j.placenta.2024.10.019_bib52","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1093\/hmg\/10.10.1093","article-title":"Paternal monoallelic expression of PEG3 in the human placenta","volume":"10","author":"Hiby","year":"2001","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.placenta.2024.10.019_bib53","doi-asserted-by":"crossref","first-page":"123","DOI":"10.3389\/fcell.2018.00123","article-title":"PEG3 deficiency results in sexually dimorphic losses and gains in the normal repertoire of placental hormones","volume":"6","author":"Tunster","year":"2018","journal-title":"Front. Cell Dev. Biol."},{"issue":"6769","key":"10.1016\/j.placenta.2024.10.019_bib54","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1038\/35000656","article-title":"Demethylation of the zygotic paternal genome","volume":"403","author":"Mayer","year":"2000","journal-title":"Nature"},{"issue":"7","key":"10.1016\/j.placenta.2024.10.019_bib55","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1001015","article-title":"The importance of imprinting in the human placenta","volume":"6","author":"Frost","year":"2010","journal-title":"PLoS Genet."},{"key":"10.1016\/j.placenta.2024.10.019_bib56","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.placenta.2016.08.093","article-title":"DNA methylation-associated repression of MEST\/PEG1 expression contributes to the invasion of extravillous trophoblast cells","volume":"46","author":"Peng","year":"2016","journal-title":"Placenta"},{"issue":"15","key":"10.1016\/j.placenta.2024.10.019_bib57","doi-asserted-by":"crossref","first-page":"5585","DOI":"10.1128\/MCB.22.15.5585-5592.2002","article-title":"Mice lacking paternally expressed Pref-1\/DLK11 display growth retardation and accelerated adiposity","volume":"22","author":"Moon","year":"2002","journal-title":"Mol. Cell Biol."},{"issue":"2","key":"10.1016\/j.placenta.2024.10.019_bib58","article-title":"Gene dosage effects of the imprinted delta-like homologue 1 (DLK11\/pref1) in development: implications for the evolution of imprinting","volume":"5","author":"da Rocha","year":"2009","journal-title":"PLoS Genet."},{"issue":"1663","key":"10.1016\/j.placenta.2024.10.019_bib59","doi-asserted-by":"crossref","DOI":"10.1098\/rstb.2014.0074","article-title":"The role and interaction of imprinted genes in human fetal growth","volume":"370","author":"Moore","year":"2015","journal-title":"Phil. Trans. Roy. Soc. Lond. B Biol. Sci."},{"issue":"3","key":"10.1016\/j.placenta.2024.10.019_bib60","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1097\/HJH.0000000000001942","article-title":"Hypermethylation of delta-like homolog 1\/maternally expressed gene 3 loci in human umbilical veins: insights into offspring vascular dysfunction born after preeclampsia","volume":"37","author":"Yu","year":"2019","journal-title":"J. Hypertens."}],"container-title":["Placenta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S014340042400691X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S014340042400691X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T10:25:52Z","timestamp":1778667952000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S014340042400691X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":60,"alternative-id":["S014340042400691X"],"URL":"https:\/\/doi.org\/10.1016\/j.placenta.2024.10.019","relation":{},"ISSN":["0143-4004"],"issn-type":[{"value":"0143-4004","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Methylation and expression of imprinted genes in circulating extracellular vesicles from women experiencing early onset preeclampsia","name":"articletitle","label":"Article Title"},{"value":"Placenta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.placenta.2024.10.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}