{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T19:42:46Z","timestamp":1786995766754,"version":"build-2736575974"},"reference-count":75,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001411","name":"Indian Council of Medical Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001411","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100019483","name":"National Honey Board","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100019483","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012117","name":"Lady Tata Memorial Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012117","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Placenta"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.placenta.2024.10.068","type":"journal-article","created":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T18:10:08Z","timestamp":1730916608000},"page":"275-284","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Methylation aberrations in partner spermatozoa and impaired expression of imprinted genes in the placentae of early-onset preeclampsia"],"prefix":"10.1016","volume":"158","author":[{"given":"Sweta","family":"Nair","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kushaan","family":"Khambata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Himangi","family":"Warke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vandana","family":"Bansal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anushree","family":"Patil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zakiya","family":"Ansari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9937-7518","authenticated-orcid":false,"given":"Nafisa H.","family":"Balasinor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.placenta.2024.10.068_bib1","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1055\/s-0037-1604471","article-title":"Preeclampsia","volume":"39","author":"Ramos","year":"2017","journal-title":"Rev. Bras. Ginecol. Obstet."},{"key":"10.1016\/j.placenta.2024.10.068_bib2","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1161\/CIRCRESAHA.118.313276","article-title":"Preeclampsia: Pathophysiology, challenges, and perspectives","volume":"124","author":"Rana","year":"2019","journal-title":"Circ. Res."},{"key":"10.1016\/j.placenta.2024.10.068_bib3","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1081\/PRG-120016792","article-title":"Summary of the NHLBI working group on research on hypertension during pregnancy","volume":"22","author":"Roberts","year":"2003","journal-title":"Hypertens. Pregnancy"},{"key":"10.1016\/j.placenta.2024.10.068_bib4","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1016\/S0002-9378(98)70160-7","article-title":"Etiology and pathogenesis of preeclampsia: current concepts","volume":"179","author":"Dekker","year":"1998","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.placenta.2024.10.068_bib5","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1056\/NEJM200103223441201","article-title":"Paternal and maternal components to the predisposition to preeclampsia","volume":"344","author":"Esplin","year":"2001","journal-title":"N. Eng. J. Med."},{"key":"10.1016\/j.placenta.2024.10.068_bib6","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/0143-4004(91)90339-H","article-title":"Current topic: pre-eclampsia and the placenta","volume":"12","author":"Redman","year":"1991","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2024.10.068_bib7","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1016\/S0002-9378(96)70056-X","article-title":"Heterogeneous causes constituting the single syndrome of preeclampsia: a hypothesis and its implications","volume":"175","author":"Ness","year":"1996","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.placenta.2024.10.068_bib8","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1097\/OGX.0b013e3182331028","article-title":"A critical review of early-onset and late-onset preeclampsia","volume":"66","author":"Raymond","year":"2011","journal-title":"Obstet. Gynecol. Surv."},{"key":"10.1016\/j.placenta.2024.10.068_bib9","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1002\/path.4394","article-title":"Differential activation of placental unfolded protein response pathways implies heterogeneity in causation of early- and late-onset pre-eclampsia","volume":"234","author":"Yung","year":"2014","journal-title":"J. Pathol."},{"issue":"Suppl 4","key":"10.1016\/j.placenta.2024.10.068_bib10","doi-asserted-by":"crossref","first-page":"S115","DOI":"10.1016\/j.ajog.2015.08.042","article-title":"Why is placentation abnormal in preeclampsia?","volume":"213","author":"Fisher","year":"2015","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.placenta.2024.10.068_bib11","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/0092-8674(84)90313-1","article-title":"Completion of mouse embryogenesis requires both the maternal and paternal genomes","volume":"37","author":"McGrath","year":"1984","journal-title":"Cell"},{"key":"10.1016\/j.placenta.2024.10.068_bib12","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1038\/308548a0","article-title":"Development of reconstituted mouse eggs suggests imprinting of the genome during gametogenesis","volume":"308","author":"Surani","year":"1984","journal-title":"Nature"},{"key":"10.1016\/j.placenta.2024.10.068_bib13","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1038\/349084a0","article-title":"The mouse insulin-like growth factor type-2 receptor is imprinted and closely linked to the Tme locus","volume":"349","author":"Barlow","year":"1991","journal-title":"Nature"},{"key":"10.1016\/j.placenta.2024.10.068_bib14","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1038\/362751a0","article-title":"Parental-origin-specific epigenetic modification of the mouse H19 gene","volume":"362","author":"Ferguson-Smith","year":"1993","journal-title":"Nature"},{"key":"10.1016\/j.placenta.2024.10.068_bib15","doi-asserted-by":"crossref","first-page":"a018382","DOI":"10.1101\/cshperspect.a018382","article-title":"Genomic imprinting in mammals","volume":"6","author":"Barlow","year":"2014","journal-title":"Cold Spring Harb. Perspect. Biol."},{"key":"10.1016\/j.placenta.2024.10.068_bib16","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1001015","article-title":"The importance of imprinting in the human placenta","volume":"6","author":"Frost","year":"2010","journal-title":"PLoS Genet."},{"key":"10.1016\/j.placenta.2024.10.068_bib17","first-page":"8934","article-title":"The expression of imprinted genes IGF2 and PHLDA2 in mid-pregnancy have predictive values for the development of pre-eclampsia","volume":"10","author":"Guo","year":"2017","journal-title":"Int. J. Clin. Exp. Med."},{"key":"10.1016\/j.placenta.2024.10.068_bib18","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.3390\/genes11101146","article-title":"Differences in placental imprinted gene expression across preeclamptic and non-preeclamptic pregnancies","volume":"11","author":"Deyssenroth","year":"2020","journal-title":"Genes"},{"key":"10.1016\/j.placenta.2024.10.068_bib19","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1186\/s12958-023-01116-3","article-title":"Paternal expressed gene 10 (PEG10) is decreased in early-onset preeclampsia","volume":"21","author":"Baird","year":"2023","journal-title":"Reprod. Biol. Endocrinol."},{"key":"10.1016\/j.placenta.2024.10.068_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajog.2008.04.020","article-title":"Differential placental gene expression in preeclampsia","volume":"199","author":"Enquobahrie","year":"2008","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.placenta.2024.10.068_bib21","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.tice.2014.04.003","article-title":"The expression of cell cycle related proteins PCNA, Ki67, p27 and p57 in normal and preeclamptic human placentas","volume":"46","author":"Unek","year":"2014","journal-title":"Tissue Cell"},{"key":"10.1016\/j.placenta.2024.10.068_bib22","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1111\/1440-1681.12468","article-title":"The expression of the imprinted gene pleckstrin homology-like domain family A member 2 in placental tissues of preeclampsia and its effects on the proliferation, migration and invasion of trophoblast cells JEG-3","volume":"42","author":"Jin","year":"2015","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"key":"10.1016\/j.placenta.2024.10.068_bib23","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/j.placenta.2009.02.011","article-title":"The H19 gene imprinting in normal pregnancy and pre-eclampsia","volume":"30","author":"Yu","year":"2009","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2024.10.068_bib24","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1097\/HJH.0000000000001942","article-title":"Hypermethylation of delta-like homolog 1\/maternally expressed gene 3 loci in human umbilical veins: insights into offspring vascular dysfunction born after preeclampsia","volume":"37","author":"Yu","year":"2019","journal-title":"J. Hypertens."},{"issue":"Suppl 5","key":"10.1016\/j.placenta.2024.10.068_bib25","doi-asserted-by":"crossref","first-page":"2253","DOI":"10.1016\/j.fertnstert.2008.07.1709","article-title":"Effect of tamoxifen treatment on global and insulin-like growth factor 2-H19 locus-specific DNA methylation in rat spermatozoa and its association with embryo loss","volume":"91","author":"Pathak","year":"2009","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.placenta.2024.10.068_bib26","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1071\/RD09154","article-title":"Disrupted imprinting status at H19 differentially methylated region is associated with resorbed embryo phenotype in rats","volume":"22","author":"Pathak","year":"2010","journal-title":"Reprod. Fertil. Dev."},{"key":"10.1016\/j.placenta.2024.10.068_bib27","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/j.lfs.2011.02.005","article-title":"Aberrant expression of imprinted genes in post-implantation rat embryos","volume":"88","author":"Kedia-Mokashi","year":"2011","journal-title":"Life Sci."},{"key":"10.1016\/j.placenta.2024.10.068_bib28","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1016\/j.fertnstert.2012.07.1143","article-title":"Methylation analysis of idiopathic recurrent spontaneous miscarriage cases reveals aberrant imprinting at H19 ICR in normozoospermic individuals","volume":"98","author":"Ankolkar","year":"2012","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.placenta.2024.10.068_bib29","first-page":"48","article-title":"DNA methylation defects in spermatozoa of male partners from couples experiencing recurrent pregnancy loss","volume":"36","author":"Khambata","year":"2021","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.placenta.2024.10.068_bib30","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/j.fertnstert.2022.12.017","article-title":"Whole genome bisulfite sequencing of sperm reveals differentially methylated regions in male partners of idiopathic recurrent pregnancy loss cases","volume":"119","author":"Irani","year":"2023","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.placenta.2024.10.068_bib31","first-page":"1122","article-title":"Report of the American College of Obstetricians and Gynecologists' task force on hypertension in pregnancy","volume":"122","year":"2013","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.placenta.2024.10.068_bib32","series-title":"WHO Laboratory Manual for the Examination and Processing of Human Semen","year":"2010"},{"key":"10.1016\/j.placenta.2024.10.068_bib33","series-title":"WHO Laboratory Manual for the Examination and Processing of Human Semen","year":"2021"},{"key":"10.1016\/j.placenta.2024.10.068_bib34","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1095\/biolreprod49.5.1083","article-title":"Effect of deoxyribonucleic acid protamination on fluorochrome staining and in situ nick-translation of murine and human mature spermatozoa","volume":"49","author":"Bianchi","year":"1993","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.placenta.2024.10.068_bib35","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1093\/bioinformatics\/18.11.1427","article-title":"MethPrimer: designing primers for methylation PCRs","volume":"18","author":"Li","year":"2002","journal-title":"Bioinformatics"},{"key":"10.1016\/j.placenta.2024.10.068_bib36","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1093\/molehr\/6.11.1019","article-title":"p57(Kip2) regulates the proper development of labyrinthine and spongiotrophoblasts","volume":"6","author":"Takahashi","year":"2000","journal-title":"Mol. Hum. Reprod."},{"key":"10.1016\/j.placenta.2024.10.068_bib37","doi-asserted-by":"crossref","first-page":"7490","DOI":"10.1073\/pnas.122039999","article-title":"Placental overgrowth in mice lacking the imprinted gene Ipl","volume":"99","author":"Frank","year":"2002","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.placenta.2024.10.068_bib38","article-title":"Low birth weight and its associated risk factors: health facility-based case-control study","volume":"15","author":"Anil","year":"2020","journal-title":"PLoS One"},{"key":"10.1016\/j.placenta.2024.10.068_bib39","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2021-058068","article-title":"Impact of gestational hypertension and pre-eclampsia on preterm birth in China: a large prospective cohort study","volume":"12","author":"An","year":"2022","journal-title":"BMJ Open"},{"key":"10.1016\/j.placenta.2024.10.068_bib40","doi-asserted-by":"crossref","first-page":"1486","DOI":"10.3390\/medicina60091486","article-title":"Health impacts of pre-eclampsia: a comprehensive analysis of maternal and neonatal outcomes","volume":"60","author":"Socol","year":"2024","journal-title":"Medicina (Kaunas)"},{"key":"10.1016\/j.placenta.2024.10.068_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.jsbmb.2020.105729","article-title":"Vitamin-D dysregulation in early- and late-onset preeclampsia: a gestational-age matched study","volume":"203","author":"Martin","year":"2020","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.placenta.2024.10.068_bib42","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1186\/s12881-019-0835-6","article-title":"Effect of prematurity on genome wide methylation in the placenta","volume":"20","author":"Schuster","year":"2019","journal-title":"BMC Med. Genet."},{"key":"10.1016\/j.placenta.2024.10.068_bib43","first-page":"497","article-title":"Impact of age on semen parameters in male partners of infertile couples in a rural tertiary care center of central India: a cross-sectional study","volume":"15","author":"Kumar","year":"2017","journal-title":"Int. J. Reprod. Biomed."},{"key":"10.1016\/j.placenta.2024.10.068_bib44","first-page":"60","article-title":"Methylation status of imprinted genes and repetitive elements in sperm DNA from infertile males, Sex","volume":"5","author":"El Hajj","year":"2011","journal-title":"Dev"},{"key":"10.1016\/j.placenta.2024.10.068_bib45","doi-asserted-by":"crossref","first-page":"2542","DOI":"10.1093\/hmg\/ddm187","article-title":"Aberrant DNA methylation of imprinted loci in sperm from oligospermic patients","volume":"16","author":"Kobayashi","year":"2007","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.placenta.2024.10.068_bib46","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1016\/0092-8674(91)90513-X","article-title":"Parental imprinting of the mouse insulin-like growth factor II gene","volume":"64","author":"DeChiara","year":"1991","journal-title":"Cell"},{"key":"10.1016\/j.placenta.2024.10.068_bib47","doi-asserted-by":"crossref","first-page":"3413","DOI":"10.1242\/dev.036061","article-title":"H19 acts as a trans regulator of the imprinted gene network controlling growth in mice","volume":"136","author":"Gabory","year":"2009","journal-title":"Development"},{"key":"10.1016\/j.placenta.2024.10.068_bib48","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.placenta.2010.10.017","article-title":"Hypomethylation along with increased H19 expression in placentas from pregnancies complicated with fetal growth restriction","volume":"32","author":"Koukoura","year":"2011","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2024.10.068_bib49","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/j.placenta.2005.07.004","article-title":"Unbalanced placental expression of imprinted genes in human intrauterine growth restriction","volume":"27","author":"McMinn","year":"2006","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2024.10.068_bib50","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.ydbio.2008.04.025","article-title":"Altered gene expression and methylation of the human chromosome 11 imprinted region in small for gestational age (SGA) placentae","volume":"320","author":"Guo","year":"2008","journal-title":"Dev. Biol."},{"key":"10.1016\/j.placenta.2024.10.068_bib51","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.placenta.2009.12.003","article-title":"Decreased placental methylation at the H19\/IGF2 imprinting control region is associated with normotensive intrauterine growth restriction but not preeclampsia","volume":"31","author":"Bourque","year":"2010","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2024.10.068_bib52","first-page":"481","article-title":"Loss of imprinting and aberrant methylation of IGF2 in placentas from pregnancies complicated with fetal growth restriction","volume":"28","author":"Koukoura","year":"2011","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.placenta.2024.10.068_bib53","doi-asserted-by":"crossref","first-page":"3344","DOI":"10.1210\/en.2005-1328","article-title":"Maternal insulin-like growth factors-I and -II act via different pathways to promote fetal growth","volume":"147","author":"Sferruzzi-Perri","year":"2006","journal-title":"Endocrinol"},{"key":"10.1016\/j.placenta.2024.10.068_bib54","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1038\/nature00819","article-title":"Placental-specific IGF-II is a major modulator of placental and fetal growth","volume":"417","author":"Const\u00e2ncia","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.placenta.2024.10.068_bib55","doi-asserted-by":"crossref","first-page":"8204","DOI":"10.1073\/pnas.0402508101","article-title":"Placental-specific insulin-like growth factor 2 (Igf2) regulates the diffusional exchange characteristics of the mouse placenta","volume":"101","author":"Sibley","year":"2004","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.placenta.2024.10.068_bib56","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.ygeno.2004.03.008","article-title":"The KCNQ1OT1 promoter, a key regulator of genomic imprinting in human chromosome 11p15.5","volume":"84","author":"Du","year":"2004","journal-title":"Genomics"},{"key":"10.1016\/j.placenta.2024.10.068_bib57","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1101\/gad.9.6.639","article-title":"Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution","volume":"9","author":"Lee","year":"1995","journal-title":"Genes Dev."},{"key":"10.1016\/j.placenta.2024.10.068_bib58","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1007\/s00109-006-0131-8","article-title":"Elevated placental expression of the imprinted PHLDA2 gene is associated with low birth weight","volume":"85","author":"Apostolidou","year":"2007","journal-title":"J. Mol. Med."},{"key":"10.1016\/j.placenta.2024.10.068_bib59","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.bone.2011.11.003","article-title":"Relationship between placental expression of the imprinted PHLDA2 gene, intrauterine skeletal growth and childhood bone mass","volume":"50","author":"Lewis","year":"2012","journal-title":"Bone"},{"key":"10.1016\/j.placenta.2024.10.068_bib60","doi-asserted-by":"crossref","first-page":"5585","DOI":"10.1128\/MCB.22.15.5585-5592.2002","article-title":"Mice lacking paternally expressed Pref-1\/Dlk1 display growth retardation and accelerated adiposity","volume":"22","author":"Moon","year":"2002","journal-title":"Mol. Cell Biol."},{"key":"10.1016\/j.placenta.2024.10.068_bib61","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1016\/j.ydbio.2007.02.043","article-title":"Restricted co-expression of Dlk1 and the reciprocally imprinted non-coding RNA, Gtl2: implications for cis-acting control","volume":"306","author":"da Rocha","year":"2007","journal-title":"Dev. Biol."},{"key":"10.1016\/j.placenta.2024.10.068_bib62","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1093\/cvr\/cvr296","article-title":"The noncanonical NOTCH ligand DLK1 exhibits a novel vascular role as a strong inhibitor of angiogenesis","volume":"93","author":"Rodriguez","year":"2012","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.placenta.2024.10.068_bib63","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/10641955.2017.1397689","article-title":"Alteration in methylation level at differential methylated regions of MEST and DLK1 in fetus of preeclampsia","volume":"37","author":"Wang","year":"2018","journal-title":"Hypertens. Pregnancy"},{"key":"10.1016\/j.placenta.2024.10.068_bib64","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/j.tig.2007.08.010","article-title":"The potential role of epigenomic dysregulation in complex human disease","volume":"23","author":"Hatchwell","year":"2007","journal-title":"Trends Genet."},{"key":"10.1016\/j.placenta.2024.10.068_bib65","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1534\/genetics.111.131912","article-title":"Environment-sensitive epigenetics and the heritability of complex diseases","volume":"189","author":"Furrow","year":"2011","journal-title":"Genetics"},{"key":"10.1016\/j.placenta.2024.10.068_bib66","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/(SICI)1097-0177(200001)217:1<1::AID-DVDY1>3.0.CO;2-4","article-title":"Expression of the imprinted genes MEST\/Mest in human and murine placenta suggests a role in angiogenesis","volume":"217","author":"Mayer","year":"2000","journal-title":"Dev. Dyn."},{"key":"10.1016\/j.placenta.2024.10.068_bib67","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1038\/2464","article-title":"Abnormal maternal behaviour and growth retardation associated with loss of the imprinted gene Mest","volume":"20","author":"Lefebvre","year":"1998","journal-title":"Nat. Genet."},{"key":"10.1016\/j.placenta.2024.10.068_bib68","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1126\/science.284.5412.330","article-title":"Regulation of maternal behavior and offspring growth by paternally expressed Peg3","volume":"284","author":"Li","year":"1999","journal-title":"Science"},{"key":"10.1016\/j.placenta.2024.10.068_bib69","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1101\/gr.157271.113","article-title":"De novo DNA demethylation and noncoding transcription define active intergenic regulatory elements","volume":"23","author":"Schlesinger","year":"2013","journal-title":"Genome Res."},{"key":"10.1016\/j.placenta.2024.10.068_bib70","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1038\/ng1699","article-title":"Deletion of Peg10, an imprinted gene acquired from a retrotransposon, causes early embryonic lethality","volume":"38","author":"Ono","year":"2006","journal-title":"Nat. Genet."},{"key":"10.1016\/j.placenta.2024.10.068_bib71","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/j.acthis.2011.11.003","article-title":"Elevated expression of PEG10 in human placentas from preeclamptic pregnancies","volume":"114","author":"Chen","year":"2012","journal-title":"Acta Histochem."},{"key":"10.1016\/j.placenta.2024.10.068_bib72","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1289\/ehp.1103927","article-title":"In utero exposures, infant growth, and DNA methylation of repetitive elements and developmentally related genes in human placenta","volume":"120","author":"Wilhelm-Benartzi","year":"2012","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.placenta.2024.10.068_bib73","article-title":"Transition of LINE-1 DNA methylation status and altered expression in first and third trimester placentas","volume":"9","author":"He","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.placenta.2024.10.068_bib74","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0025254","article-title":"Birthweight, maternal weight trajectories and global DNA methylation of LINE-1 repetitive elements","volume":"6","author":"Michels","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.placenta.2024.10.068_bib75","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2019.16777","article-title":"Association of periconception paternal body mass index with persistent changes in DNA methylation of offspring in childhood","volume":"2","author":"Noor","year":"2019","journal-title":"JAMA Netw. Open"}],"container-title":["Placenta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400424007409?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400424007409?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T03:25:14Z","timestamp":1733973914000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0143400424007409"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":75,"alternative-id":["S0143400424007409"],"URL":"https:\/\/doi.org\/10.1016\/j.placenta.2024.10.068","relation":{},"ISSN":["0143-4004"],"issn-type":[{"value":"0143-4004","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Methylation aberrations in partner spermatozoa and impaired expression of imprinted genes in the placentae of early-onset preeclampsia","name":"articletitle","label":"Article Title"},{"value":"Placenta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.placenta.2024.10.068","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}