{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T14:13:21Z","timestamp":1787062401574,"version":"build-2736575974"},"reference-count":68,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T00:00:00Z","timestamp":1744848000000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100012285","name":"BC Children&apos;s Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012285","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["SVB-158613"],"award-info":[{"award-number":["SVB-158613"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["PJT-169131"],"award-info":[{"award-number":["PJT-169131"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Placenta"],"published-print":{"date-parts":[[2025,4]]},"DOI":"10.1016\/j.placenta.2025.04.014","type":"journal-article","created":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T12:18:33Z","timestamp":1744892313000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Some lessons learned from genomic and epigenomic studies of the placenta"],"prefix":"10.1016","author":[{"given":"Amy M.","family":"Inkster","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah J.","family":"Illing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2010-6174","authenticated-orcid":false,"given":"Wendy P.","family":"Robinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.placenta.2025.04.014_bib1","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1093\/hmg\/ddx391","article-title":"Mining DNA methylation alterations towards a classification of placental pathologies","volume":"27","author":"Wilson","year":"2018","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.placenta.2025.04.014_bib2","article-title":"The human placenta: new perspectives on its formation and function during early pregnancy","volume":"290","author":"Burton","year":"2023","journal-title":"Proc. Biol. Sci."},{"key":"10.1016\/j.placenta.2025.04.014_bib3","doi-asserted-by":"crossref","first-page":"dev163428","DOI":"10.1242\/dev.163428","article-title":"Development of the human placenta","volume":"146","author":"Turco","year":"2019","journal-title":"Development"},{"key":"10.1016\/j.placenta.2025.04.014_bib4","author":"Wang","year":"2024","journal-title":"Chromosomal Instability in Human Trophoblast Stem Cells and Placentas"},{"key":"10.1016\/j.placenta.2025.04.014_bib5","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-024-54953-0","article-title":"On the origin of mitosis-derived human embryo aneuploidy","volume":"15","author":"Leem","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.placenta.2025.04.014_bib6","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1038\/s41586-021-03345-1","article-title":"Inherent mosaicism and extensive mutation of human placentas","volume":"592","author":"Coorens","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.placenta.2025.04.014_bib7","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1136\/jmg.33.7.529","article-title":"Confined placental mosaicism","volume":"33","author":"Kalousek","year":"1996","journal-title":"J. Med. Genet."},{"key":"10.1016\/j.placenta.2025.04.014_bib8","doi-asserted-by":"crossref","first-page":"1745","DOI":"10.1093\/humrep\/des072","article-title":"Patterns of placental development evaluated by X chromosome inactivation profiling provide a basis to evaluate the origin of epigenetic variation","volume":"27","author":"Pe\u00f1aherrera","year":"2012","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.placenta.2025.04.014_bib9","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1002\/pd.483","article-title":"Origin of amnion and implications for evaluation of the fetal genotype in cases of mosaicism","volume":"22","author":"Robinson","year":"2002","journal-title":"Prenat. Diagn."},{"key":"10.1016\/j.placenta.2025.04.014_bib10","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/s12864-020-07186-6","article-title":"Cell-specific characterization of the placental methylome","volume":"22","author":"Yuan","year":"2021","journal-title":"BMC Genom."},{"key":"10.1016\/j.placenta.2025.04.014_bib11","series-title":"Human Reproductive and Prenatal Genetics","first-page":"289","article-title":"Epigenetic modifications in the human placenta","author":"Robinson","year":"2023"},{"key":"10.1016\/j.placenta.2025.04.014_bib12","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1136\/jmg.33.7.529","article-title":"Confined placental mosaicism","volume":"33","author":"Kalousek","year":"1996","journal-title":"J. Med. Genet."},{"key":"10.1016\/j.placenta.2025.04.014_bib13","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1093\/humupd\/dmab009","article-title":"Confined placental mosaicism and the association with pregnancy outcome and fetal growth: a review of the literature","volume":"27","author":"Eggenhuizen","year":"2021","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.placenta.2025.04.014_bib14","first-page":"917","article-title":"Meiotic origin of trisomy in confined placental mosaicism is correlated with presence of fetal uniparental disomy, high levels of trisomy in trophoblast, and increased risk of fetal intrauterine growth restriction","volume":"60","author":"Robinson","year":"1997","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.placenta.2025.04.014_bib15","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1136\/jmg.40.3.175","article-title":"Clinical aspects, prenatal diagnosis, and pathogenesis of trisomy 16 mosaicism","volume":"40","author":"Yong","year":"2003","journal-title":"J. Med. Genet."},{"key":"10.1016\/j.placenta.2025.04.014_bib16","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1002\/(SICI)1096-8628(19980901)79:2<121::AID-AJMG8>3.0.CO;2-T","article-title":"Trisomy 16 and trisomy 16 Mosaicism: a review","volume":"79","author":"Benn","year":"1998","journal-title":"Am. J. Med. Genet."},{"key":"10.1016\/j.placenta.2025.04.014_bib17","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1038\/gim.2017.23","article-title":"Mosaic trisomy 16: what are the obstetric and long-term childhood outcomes?","volume":"19","author":"Sparks","year":"2017","journal-title":"Genet. Med."},{"key":"10.1016\/j.placenta.2025.04.014_bib18","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1002\/pd.1534","article-title":"The association between preeclampsia and placental trisomy 16 mosaicism","volume":"26","author":"Yong","year":"2006","journal-title":"Prenat. Diagn."},{"key":"10.1016\/j.placenta.2025.04.014_bib19","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s10020-020-00253-4","article-title":"Genomic imbalances in the placenta are associated with poor fetal growth","volume":"27","author":"Del Gobbo","year":"2021","journal-title":"Mol Med"},{"key":"10.1016\/j.placenta.2025.04.014_bib20","doi-asserted-by":"crossref","first-page":"R30","DOI":"10.1186\/gb-2014-15-2-r30","article-title":"Using high-density DNA methylation arrays to profile copy number alterations","volume":"15","author":"Feber","year":"2014","journal-title":"Genome Biol."},{"key":"10.1016\/j.placenta.2025.04.014_bib21","doi-asserted-by":"crossref","DOI":"10.1093\/bioinformatics\/btae029","article-title":"Conumee 2.0: enhanced copy-number variation analysis from DNA methylation arrays for humans and mice","volume":"40","author":"Daenekas","year":"2024","journal-title":"Bioinformatics"},{"key":"10.1016\/j.placenta.2025.04.014_bib22","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.placenta.2014.01.001","article-title":"Overlapping DNA methylation profile between placentas with trisomy 16 and early-onset preeclampsia","volume":"35","author":"Blair","year":"2014","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2025.04.014_bib23","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/1756-8935-4-10","article-title":"Genome-wide mapping of imprinted differentially methylated regions by DNA methylation profiling of human placentas from triploidies","volume":"4","author":"Yuen","year":"2011","journal-title":"Epigenetics Chromatin"},{"key":"10.1016\/j.placenta.2025.04.014_bib24","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1038\/nature26002","article-title":"Placentation defects are highly prevalent in embryonic lethal mouse mutants","volume":"555","author":"Perez-Garcia","year":"2018","journal-title":"Nature"},{"key":"10.1016\/j.placenta.2025.04.014_bib25","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1038\/ng.3895","article-title":"Variants in the fetal genome near FLT1 are associated with risk of preeclampsia","volume":"49","author":"McGinnis","year":"2017","journal-title":"Nat. Genet."},{"key":"10.1016\/j.placenta.2025.04.014_bib26","doi-asserted-by":"crossref","first-page":"2384","DOI":"10.1038\/s41467-022-30007-1","article-title":"Placental multi-omics integration identifies candidate functional genes for birthweight","volume":"13","author":"Tekola-Ayele","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.placenta.2025.04.014_bib27","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1038\/s41591-018-0021-y","article-title":"Convergence of placenta biology and genetic risk for schizophrenia","volume":"24","author":"Ursini","year":"2018","journal-title":"Nat Med"},{"key":"10.1016\/j.placenta.2025.04.014_bib28","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2019789118","article-title":"Placental genomic risk scores and early neurodevelopmental outcomes","volume":"118","author":"Ursini","year":"2021","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.placenta.2025.04.014_bib29","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1177\/0956797611417632","article-title":"False-positive psychology: undisclosed flexibility in data collection and analysis allows presenting anything as significant","volume":"22","author":"Simmons","year":"2011","journal-title":"Psychol. Sci."},{"key":"10.1016\/j.placenta.2025.04.014_bib30","doi-asserted-by":"crossref","DOI":"10.1037\/lhb0000579","article-title":"Degrees of freedom as a breeding ground for biases-A threat to forensic practice","author":"Oeberst","year":"2024","journal-title":"Law Hum. Behav."},{"key":"10.1016\/j.placenta.2025.04.014_bib31","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2018.00083","article-title":"Adjusting for batch effects in DNA methylation microarray data, a lesson learned","volume":"9","author":"Price","year":"2018","journal-title":"Front. Genet."},{"key":"10.1016\/j.placenta.2025.04.014_bib32","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.placenta.2013.11.005","article-title":"Optimising sample collection for placental research","volume":"35","author":"Burton","year":"2014","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2025.04.014_bib33","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.placenta.2019.01.006","article-title":"Considerations when processing and interpreting genomics data of the placenta","volume":"84","author":"Konwar","year":"2019","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2025.04.014_bib34","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1186\/s13072-023-00507-5","article-title":"The application of epiphenotyping approaches to DNA methylation array studies of the human placenta","volume":"16","author":"Khan","year":"2023","journal-title":"Epigenetics Chromatin"},{"key":"10.1016\/j.placenta.2025.04.014_bib35","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1093\/humupd\/dmae006","article-title":"Revealing the molecular landscape of human placenta: a systematic review and meta-analysis of single-cell RNA sequencing studies","volume":"30","author":"Derisoud","year":"2024","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.placenta.2025.04.014_bib36","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1038\/s41588-023-01647-w","article-title":"Single-nucleus multi-omic profiling of human placental syncytiotrophoblasts identifies cellular trajectories during pregnancy","volume":"56","author":"Wang","year":"2024","journal-title":"Nat. Genet."},{"key":"10.1016\/j.placenta.2025.04.014_bib37","doi-asserted-by":"crossref","unstructured":"R. Pique-Regi, R. Romero, A.L. Tarca, E.D. Sendler, Y. Xu, V. Garcia-Flores, Y. Leng, F. Luca, S.S. Hassan, N. Gomez-Lopez, Single cell transcriptional signatures of the human placenta in term and preterm parturition, Elife 8 (n.d.) e52004. https:\/\/doi.org\/10.7554\/eLife.52004.","DOI":"10.7554\/eLife.52004"},{"key":"10.1016\/j.placenta.2025.04.014_bib38","doi-asserted-by":"crossref","first-page":"5478","DOI":"10.1073\/pnas.0508035103","article-title":"Gene expression patterns in human placenta","volume":"103","author":"Sood","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.placenta.2025.04.014_bib39","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.placenta.2004.07.003","article-title":"The correlation between sampling site and gene expression in the term human placenta","volume":"26","author":"Wyatt","year":"2005","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2025.04.014_bib40","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.placenta.2009.12.002","article-title":"Differences in gene expression dependent on sampling site in placental tissue of fetuses with intrauterine growth restriction","volume":"31","author":"Tzschoppe","year":"2010","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2025.04.014_bib41","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1016\/j.placenta.2015.06.011","article-title":"Placental expression of imprinted genes varies with sampling site and mode of delivery","volume":"36","author":"Janssen","year":"2015","journal-title":"Placenta"},{"key":"10.1016\/j.placenta.2025.04.014_bib43","author":"Lemaire","year":"2024","journal-title":"Examining Fetal Sex-Specific Placental DNA Methylation Intensities and Variability Post In Vitro Fertilization"},{"key":"10.1016\/j.placenta.2025.04.014_bib44","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1038\/s41467-017-01586-1","article-title":"Obligatory and facilitative allelic variation in the DNA methylome within common disease-associated loci","volume":"9","author":"Bell","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.placenta.2025.04.014_bib45","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1186\/s13059-017-1173-7","article-title":"Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome","volume":"18","author":"Cheung","year":"2017","journal-title":"Genome Biol."},{"key":"10.1016\/j.placenta.2025.04.014_bib46","doi-asserted-by":"crossref","first-page":"R10","DOI":"10.1186\/gb-2011-12-1-r10","article-title":"DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines","volume":"12","author":"Bell","year":"2011","journal-title":"Genome Biol."},{"key":"10.1016\/j.placenta.2025.04.014_bib47","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1186\/s13059-017-1250-y","article-title":"Genetic-epigenetic interactions in cis: a major focus in the post-GWAS era","volume":"18","author":"Do","year":"2017","journal-title":"Genome Biol."},{"key":"10.1016\/j.placenta.2025.04.014_bib48","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1007785","article-title":"Genetic variants influence on the placenta regulatory landscape","volume":"14","author":"Delahaye","year":"2018","journal-title":"PLoS Genet."},{"key":"10.1016\/j.placenta.2025.04.014_bib49","doi-asserted-by":"crossref","first-page":"3432","DOI":"10.1093\/hmg\/ddx265","article-title":"Expression quantitative trait loci (eQTLs) in human placentas suggest developmental origins of complex diseases","volume":"26","author":"Peng","year":"2017","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.placenta.2025.04.014_bib50","doi-asserted-by":"crossref","first-page":"R8","DOI":"10.1186\/gb-2012-13-2-r8","article-title":"Population-specificity of human DNA methylation","volume":"13","author":"Fraser","year":"2012","journal-title":"Genome Biol."},{"key":"10.1016\/j.placenta.2025.04.014_bib51","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1038\/s41590-018-0049-7","article-title":"Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors","volume":"19","author":"Patin","year":"2018","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.placenta.2025.04.014_bib52","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.20532","article-title":"Differential methylation between ethnic sub-groups reflects the effect of genetic ancestry and environmental exposures","volume":"6","author":"Galanter","year":"2017","journal-title":"Elife"},{"key":"10.1016\/j.placenta.2025.04.014_bib53","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1534\/genetics.113.151381","article-title":"Genome-wide variation of cytosine modifications between European and African populations and the implications for complex traits","volume":"194","author":"Moen","year":"2013","journal-title":"Genetics"},{"key":"10.1016\/j.placenta.2025.04.014_bib54","doi-asserted-by":"crossref","first-page":"2713","DOI":"10.1038\/s41467-024-47005-0","article-title":"Genetic control of DNA methylation is largely shared across European and East Asian populations","volume":"15","author":"Hatton","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.placenta.2025.04.014_bib55","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2023.1125972","article-title":"Ancestry dependent balancing selection of placental dysferlin at high-altitude","volume":"11","author":"Gundling","year":"2023","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.placenta.2025.04.014_bib56","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/s12881-019-0768-0","article-title":"Association of a placental Interleukin-6 genetic variant (rs1800796) with DNA methylation, gene expression and risk of acute chorioamnionitis","volume":"20","author":"Konwar","year":"2019","journal-title":"BMC Med. Genet."},{"key":"10.1016\/j.placenta.2025.04.014_bib57","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1186\/s13072-019-0296-3","article-title":"Accurate ethnicity prediction from placental DNA methylation data","volume":"12","author":"Yuan","year":"2019","journal-title":"Epigenetics Chromatin"},{"key":"10.1016\/j.placenta.2025.04.014_bib58","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1016\/j.fertnstert.2010.04.003","article-title":"The relationship between blastocyst morphology, chromosomal abnormality, and embryo gender","volume":"95","author":"Alfarawati","year":"2011","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.placenta.2025.04.014_bib59","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1007\/s10815-009-9337-3","article-title":"Blastocyst transfer and gender: IVF versus ICSI","volume":"26","author":"Hentemann","year":"2009","journal-title":"J. Assist. Reprod. Genet."},{"key":"10.1016\/j.placenta.2025.04.014_bib60","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/S0140-6736(20)31561-0","article-title":"Sex and gender: modifiers of health, disease, and medicine","volume":"396","author":"Mauvais-Jarvis","year":"2020","journal-title":"Lancet"},{"key":"10.1016\/j.placenta.2025.04.014_bib61","doi-asserted-by":"crossref","first-page":"2044","DOI":"10.1016\/j.cell.2023.04.014","article-title":"Quality control and analytic best practices for testing genetic models of sex differences in large populations","volume":"186","author":"Khramtsova","year":"2023","journal-title":"Cell"},{"key":"10.1016\/j.placenta.2025.04.014_bib62","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1017\/S2040174415001348","article-title":"When are sex-specific effects really sex-specific?","volume":"6","author":"Chin","year":"2015","journal-title":"J Dev Orig Health Dis"},{"key":"10.1016\/j.placenta.2025.04.014_bib63","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1038\/npp.2016.79","article-title":"Incorporating sex as a biological variable in neuropsychiatric research: where are we now and where should we Be?","volume":"42","author":"Joel","year":"2017","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.placenta.2025.04.014_bib64","doi-asserted-by":"crossref","first-page":"2241","DOI":"10.1523\/JNEUROSCI.5372-11.2012","article-title":"Sex differences in the brain: the not so inconvenient truth","volume":"32","author":"McCarthy","year":"2012","journal-title":"J. Neurosci."},{"key":"10.1016\/j.placenta.2025.04.014_bib65","doi-asserted-by":"crossref","DOI":"10.1136\/bmjgh-2021-005714","article-title":"Stop \u2018controlling\u2019 for sex and gender in global health research","volume":"6","author":"Shapiro","year":"2021","journal-title":"BMJ Glob. Health"},{"key":"10.1016\/j.placenta.2025.04.014_bib66","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0215987","article-title":"Insights from deconvolution of cell subtype proportions enhance the interpretation of functional genomic data","volume":"14","author":"Kong","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.placenta.2025.04.014_bib67","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1038\/s42003-023-04623-6","article-title":"Placental cell type deconvolution reveals that cell proportions drive preeclampsia gene expression differences","volume":"6","author":"Campbell","year":"2023","journal-title":"Commun. Biol."},{"key":"10.1016\/j.placenta.2025.04.014_bib68","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1038\/s41562-016-0021","article-title":"A manifesto for reproducible science","volume":"1","author":"Munaf\u00f2","year":"2017","journal-title":"Nat. Hum. Behav."},{"key":"10.1016\/j.placenta.2025.04.014_bib69","article-title":"Recommendations to enhance rigor and reproducibility in biomedical research","volume":"9","author":"Brito","year":"2020","journal-title":"GigaScience"}],"container-title":["Placenta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400425001237?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400425001237?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T18:10:01Z","timestamp":1777486201000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0143400425001237"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":68,"alternative-id":["S0143400425001237"],"URL":"https:\/\/doi.org\/10.1016\/j.placenta.2025.04.014","relation":{},"ISSN":["0143-4004"],"issn-type":[{"value":"0143-4004","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Some lessons learned from genomic and epigenomic studies of the placenta","name":"articletitle","label":"Article Title"},{"value":"Placenta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.placenta.2025.04.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Crown Copyright \u00a9 2025 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}