{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T08:46:39Z","timestamp":1777106799022,"version":"3.51.4"},"reference-count":21,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100017950","name":"Shanghai Municipal Health Commission","doi-asserted-by":"publisher","award":["202440131"],"award-info":[{"award-number":["202440131"]}],"id":[{"id":"10.13039\/100017950","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology of the People's Republic of China","doi-asserted-by":"publisher","award":["2023YFC2705901"],"award-info":[{"award-number":["2023YFC2705901"]}],"id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004921","name":"Shanghai Jiao Tong University","doi-asserted-by":"publisher","award":["YG2024QNA59"],"award-info":[{"award-number":["YG2024QNA59"]}],"id":[{"id":"10.13039\/501100004921","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004921","name":"Shanghai Jiao Tong University","doi-asserted-by":"publisher","award":["YG2023ZD26"],"award-info":[{"award-number":["YG2023ZD26"]}],"id":[{"id":"10.13039\/501100004921","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003399","name":"Science and Technology Commission of Shanghai Municipality","doi-asserted-by":"publisher","award":["23DZ2300300"],"award-info":[{"award-number":["23DZ2300300"]}],"id":[{"id":"10.13039\/501100003399","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003399","name":"Science and Technology Commission of Shanghai Municipality","doi-asserted-by":"publisher","award":["22Y11902300"],"award-info":[{"award-number":["22Y11902300"]}],"id":[{"id":"10.13039\/501100003399","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Placenta"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1016\/j.placenta.2025.06.024","type":"journal-article","created":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T04:38:49Z","timestamp":1751431129000},"page":"268-275","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Placental epigenetic and transcriptional dysregulation in type I selective fetal growth restriction"],"prefix":"10.1016","volume":"168","author":[{"given":"Yan","family":"Bi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiawen","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yucheng","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuhong","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Gao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juanxiu","family":"Lv","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanlin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"12","key":"10.1016\/j.placenta.2025.06.024_bib1","doi-asserted-by":"crossref","first-page":"1684","DOI":"10.1111\/1471-0528.17891","article-title":"Diagnosis and management of selective fetal growth restriction in monochorionic twin pregnancies: a cross-sectional international survey","volume":"131","author":"Prasad","year":"2024","journal-title":"Bjog"},{"issue":"1","key":"10.1016\/j.placenta.2025.06.024_bib2","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1002\/uog.20114","article-title":"Perinatal outcome of monochorionic twin pregnancy complicated by selective fetal growth restriction according to management: systematic review and meta-analysis","volume":"53","author":"Townsend","year":"2019","journal-title":"Ultrasound Obstet. Gynecol."},{"issue":"9","key":"10.1016\/j.placenta.2025.06.024_bib3","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/S2352-4642(22)00159-6","article-title":"Long-term effects of selective fetal growth restriction (LEMON): a cohort study of neurodevelopmental outcome in growth discordant identical twins in the Netherlands","volume":"6","author":"Groene","year":"2022","journal-title":"Lancet Child Adolesc Health"},{"key":"10.1016\/j.placenta.2025.06.024_bib4","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.placenta.2024.09.005","article-title":"Mitochondrial dysfunction and oxidative stress in selective fetal growth restriction","volume":"156","author":"Hu","year":"2024","journal-title":"Placenta"},{"issue":"2","key":"10.1016\/j.placenta.2025.06.024_bib5","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1002\/uog.26111","article-title":"Determinants of placental insufficiency in fetal growth restriction","volume":"61","author":"Dall'Asta","year":"2023","journal-title":"Ultrasound Obstet. Gynecol."},{"issue":"5","key":"10.1016\/j.placenta.2025.06.024_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajog.2020.05.008","article-title":"Monochorionic twins with selective fetal growth restriction: insight from placental whole-transcriptome analysis","volume":"223","author":"Li","year":"2020","journal-title":"Am. J. Obstet. Gynecol."},{"issue":"9","key":"10.1016\/j.placenta.2025.06.024_bib7","doi-asserted-by":"crossref","first-page":"1688","DOI":"10.1111\/aogs.14204","article-title":"Placental characteristics in different types of selective fetal growth restriction in monochorionic diamniotic twins","volume":"100","author":"Wang","year":"2021","journal-title":"Acta Obstet. Gynecol. Scand."},{"issue":"8","key":"10.1016\/j.placenta.2025.06.024_bib8","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1038\/s41366-024-01538-y","article-title":"An epigenome-wide association study of waist circumference in Chinese monozygotic twins","volume":"48","author":"Xing","year":"2024","journal-title":"Int. J. Obes."},{"issue":"3","key":"10.1016\/j.placenta.2025.06.024_bib9","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1080\/19768354.2021.1925741","article-title":"DNA methylation and gene expression patterns are widely altered in fetal growth restriction and associated with FGR development","volume":"25","author":"Lee","year":"2021","journal-title":"Anim. Cell Syst."},{"issue":"6","key":"10.1016\/j.placenta.2025.06.024_bib10","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1007\/s40291-022-00611-4","article-title":"Epigenetics beyond fetal growth restriction: a comprehensive overview","volume":"26","author":"Salmeri","year":"2022","journal-title":"Mol. Diagn. Ther."},{"issue":"9","key":"10.1016\/j.placenta.2025.06.024_bib11","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1002\/pd.6206","article-title":"Gestational age at birth and outcome in monochorionic twins with different types of selective fetal growth restriction: a systematic literature review","volume":"42","author":"El","year":"2022","journal-title":"Prenat. Diagn."},{"issue":"2","key":"10.1016\/j.placenta.2025.06.024_bib12","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1002\/uog.19078","article-title":"Prediction of adverse pregnancy outcome in monochorionic diamniotic twin pregnancy complicated by selective fetal growth restriction","volume":"53","author":"Monaghan","year":"2019","journal-title":"Ultrasound Obstet. Gynecol."},{"issue":"1","key":"10.1016\/j.placenta.2025.06.024_bib13","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1002\/uog.19013","article-title":"Consensus definition and essential reporting parameters of selective fetal growth restriction in twin pregnancy: a Delphi procedure","volume":"53","author":"Khalil","year":"2019","journal-title":"Ultrasound Obstet. Gynecol."},{"issue":"4","key":"10.1016\/j.placenta.2025.06.024_bib14","article-title":"Comprehensive characterization, annotation and innovative use of Infinium DNA methylation BeadChip probes","volume":"45","author":"Zhou","year":"2017","journal-title":"Nucleic Acids Res."},{"issue":"3","key":"10.1016\/j.placenta.2025.06.024_bib15","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1016\/j.fertnstert.2016.04.038","article-title":"Assisted reproductive technology and perinatal outcomes: conventional versus discordant-sibling design","volume":"106","author":"Dhalwani","year":"2016","journal-title":"Fertil. Steril."},{"issue":"3","key":"10.1016\/j.placenta.2025.06.024_bib16","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.ajog.2021.11.1357","article-title":"Clinical opinion: the diagnosis and management of suspected fetal growth restriction: an evidence-based approach","volume":"226","author":"Lees","year":"2022","journal-title":"Am. J. Obstet. Gynecol."},{"issue":"2","key":"10.1016\/j.placenta.2025.06.024_bib17","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.ogc.2021.02.001","article-title":"Placental function and the development of fetal overgrowth and fetal growth restriction","volume":"48","author":"Dumolt","year":"2021","journal-title":"Obstet. Gynecol. Clin. N. Am."},{"issue":"1","key":"10.1016\/j.placenta.2025.06.024_bib18","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1186\/s12964-022-00943-y","article-title":"HK2: a potential regulator of osteoarthritis via glycolytic and non-glycolytic pathways","volume":"20","author":"Bao","year":"2022","journal-title":"Cell Commun. Signal."},{"issue":"3","key":"10.1016\/j.placenta.2025.06.024_bib19","doi-asserted-by":"crossref","DOI":"10.1530\/REP-24-0093","article-title":"RNA-binding protein SORBS2 increases human trophoblast cell migration via stabilizing HK2 mRNA in preeclampsia","volume":"168","author":"Song","year":"2024","journal-title":"Reproduction"},{"key":"10.1016\/j.placenta.2025.06.024_bib20","doi-asserted-by":"crossref","DOI":"10.3389\/fmolb.2023.1248771","article-title":"Elevated expression of glycolytic genes as a prominent feature of early-onset preeclampsia: insights from integrative transcriptomic analysis","volume":"10","author":"He","year":"2023","journal-title":"Front. Mol. Biosci."},{"issue":"11","key":"10.1016\/j.placenta.2025.06.024_bib21","doi-asserted-by":"crossref","first-page":"4088","DOI":"10.1111\/cas.14614","article-title":"Hypoxia-inducible hexokinase-2 enhances anti-apoptotic function via activating autophagy in multiple myeloma","volume":"111","author":"Ikeda","year":"2020","journal-title":"Cancer Sci."}],"container-title":["Placenta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400425002310?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400425002310?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T08:17:15Z","timestamp":1777105035000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0143400425002310"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":21,"alternative-id":["S0143400425002310"],"URL":"https:\/\/doi.org\/10.1016\/j.placenta.2025.06.024","relation":{},"ISSN":["0143-4004"],"issn-type":[{"value":"0143-4004","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Placental epigenetic and transcriptional dysregulation in type I selective fetal growth restriction","name":"articletitle","label":"Article Title"},{"value":"Placenta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.placenta.2025.06.024","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}