{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T06:08:08Z","timestamp":1779430088246,"version":"3.53.1"},"reference-count":50,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology of the People's Republic of China","doi-asserted-by":"publisher","award":["2025YFC2708002"],"award-info":[{"award-number":["2025YFC2708002"]}],"id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology of the People's Republic of China","doi-asserted-by":"publisher","award":["2021YFC2701103"],"award-info":[{"award-number":["2021YFC2701103"]}],"id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology of the People's Republic of China","doi-asserted-by":"publisher","award":["2021YFC2701100"],"award-info":[{"award-number":["2021YFC2701100"]}],"id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012232","name":"National Key Clinical Specialty Discipline Construction Program of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012232","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82171654"],"award-info":[{"award-number":["82171654"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Placenta"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1016\/j.placenta.2026.03.022","type":"journal-article","created":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T15:53:32Z","timestamp":1774972412000},"page":"1-13","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Trophoblast KHSRP deficiency induces DNA damage and apoptosis via TFPI2 in unexplained spontaneous miscarriage"],"prefix":"10.1016","volume":"179","author":[{"given":"Gehui","family":"Jin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinyuan","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoye","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengjie","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenxue","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7685-0675","authenticated-orcid":false,"given":"Chan","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.placenta.2026.03.022_bib1","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1016\/j.fertnstert.2023.09.006","article-title":"Series of overviews on miscarriage and recurrent miscarriage","volume":"120","author":"van Wely","year":"2023","journal-title":"Fertil. Steril."},{"issue":"1","key":"10.1016\/j.placenta.2026.03.022_bib2","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1038\/s41572-020-00228-z","article-title":"Recurrent pregnancy loss","volume":"6","author":"Dimitriadis","year":"2020","journal-title":"Nat. Rev. Dis. Primers"},{"issue":"10285","key":"10.1016\/j.placenta.2026.03.022_bib3","doi-asserted-by":"crossref","first-page":"1658","DOI":"10.1016\/S0140-6736(21)00682-6","article-title":"Miscarriage matters: the epidemiological, physical, psychological, and economic costs of early pregnancy loss","volume":"397","author":"Quenby","year":"2021","journal-title":"Lancet"},{"issue":"3","key":"10.1016\/j.placenta.2026.03.022_bib4","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.7150\/ijbs.68335","article-title":"Insight of autophagy in spontaneous miscarriage","volume":"18","author":"Qin","year":"2022","journal-title":"Int. J. Biol. Sci."},{"issue":"1","key":"10.1016\/j.placenta.2026.03.022_bib5","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.ogc.2014.10.002","article-title":"Recurrent pregnancy loss: evaluation and treatment","volume":"42","author":"Shahine","year":"2015","journal-title":"Obstet. Gynecol. Clin. N. Am."},{"issue":"9","key":"10.1016\/j.placenta.2026.03.022_bib6","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/j.kjms.2017.06.012","article-title":"Placental apoptosis in recurrent miscarriage","volume":"33","author":"Atia","year":"2017","journal-title":"Kaohsiung J. Med. Sci."},{"issue":"10","key":"10.1016\/j.placenta.2026.03.022_bib7","doi-asserted-by":"crossref","first-page":"2255","DOI":"10.1080\/15548627.2024.2362122","article-title":"The novel lnc-HZ12 suppresses autophagy degradation of BBC3 by preventing its interactions with HSPA8 to induce trophoblast cell apoptosis","volume":"20","author":"Zhao","year":"2024","journal-title":"Autophagy"},{"key":"10.1016\/j.placenta.2026.03.022_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2024.116815","article-title":"The crosstalk between cell death and pregnancy related diseases: a narrative review","volume":"176","author":"Xie","year":"2024","journal-title":"Biomed. Pharmacother."},{"issue":"1","key":"10.1016\/j.placenta.2026.03.022_bib9","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0086791","article-title":"In vivo and in vitro evidence for placental DNA damage in preeclampsia","volume":"9","author":"Tadesse","year":"2014","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.placenta.2026.03.022_bib10","doi-asserted-by":"crossref","DOI":"10.3390\/cells10040857","article-title":"A role for RAGE in DNA double strand breaks (DSBs) detected in pathological placentas and trophoblast cells","volume":"10","author":"Tsai","year":"2021","journal-title":"Cells"},{"issue":"6","key":"10.1016\/j.placenta.2026.03.022_bib11","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1007\/s10565-021-09583-3","article-title":"Novel lnc-HZ03 and miR-hz03 promote BPDE-induced human trophoblastic cell apoptosis and induce miscarriage by upregulating p53\/SAT1 pathway","volume":"37","author":"Liang","year":"2021","journal-title":"Cell Biol. Toxicol."},{"key":"10.1016\/j.placenta.2026.03.022_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2023.131543","article-title":"BPDE exposure promotes trophoblast cell pyroptosis and induces miscarriage by up-regulating lnc-HZ14\/ZBP1\/NLRP3 axis","volume":"455","author":"Wang","year":"2023","journal-title":"J. Hazard. Mater."},{"issue":"5","key":"10.1016\/j.placenta.2026.03.022_bib13","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1016\/j.cell.2016.05.008","article-title":"Zika virus infection during pregnancy in mice causes placental damage and fetal demise","volume":"165","author":"Miner","year":"2016","journal-title":"Cell"},{"issue":"25","key":"10.1016\/j.placenta.2026.03.022_bib14","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2216206120","article-title":"Trophoblast PR-SET7 dysfunction induces viral mimicry response and necroptosis associated with recurrent miscarriage","volume":"120","author":"Zhou","year":"2023","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"6","key":"10.1016\/j.placenta.2026.03.022_bib15","article-title":"Roles of K(H)SRP in modulating gene transcription throughout cancer progression: insights from cellular studies to clinical perspectives","volume":"1879","author":"Yang","year":"2024","journal-title":"Biochim. Biophys. Acta Rev. Canc"},{"issue":"10","key":"10.1016\/j.placenta.2026.03.022_bib16","doi-asserted-by":"crossref","first-page":"5772","DOI":"10.1093\/nar\/gkac337","article-title":"Intra-axonal translation of Khsrp mRNA slows axon regeneration by destabilizing localized mRNAs","volume":"50","author":"Patel","year":"2022","journal-title":"Nucleic Acids Res."},{"issue":"21","key":"10.1016\/j.placenta.2026.03.022_bib17","doi-asserted-by":"crossref","first-page":"3602","DOI":"10.1158\/0008-5472.CAN-24-0927","article-title":"KHSRP stabilizes m6A-Modified transcripts to activate FAK signaling and promote pancreatic ductal adenocarcinoma progression","volume":"84","author":"Xu","year":"2024","journal-title":"Cancer Res."},{"issue":"8","key":"10.1016\/j.placenta.2026.03.022_bib18","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1038\/s41419-024-06886-1","article-title":"KHSRP ameliorates acute liver failure by regulating pre-mRNA splicing through its interaction with SF3B1","volume":"15","author":"Li","year":"2024","journal-title":"Cell Death Dis."},{"issue":"12","key":"10.1016\/j.placenta.2026.03.022_bib19","doi-asserted-by":"crossref","first-page":"3781","DOI":"10.7150\/ijbs.85063","article-title":"Intergenic CircRNA Circ_0007379 inhibits colorectal cancer progression by modulating miR-320a biogenesis in a KSRP-dependent manner","volume":"19","author":"Long","year":"2023","journal-title":"Int. J. Biol. Sci."},{"issue":"9","key":"10.1016\/j.placenta.2026.03.022_bib20","first-page":"2314","article-title":"Acetylated KHSRP impairs DNA-damage-response-related mRNA decay and facilitates prostate cancer tumorigenesis","volume":"18","author":"Yuan","year":"2024","journal-title":"Mol. Oncol."},{"key":"10.1016\/j.placenta.2026.03.022_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.cellsig.2022.110447","article-title":"KHSRP modulated cell proliferation and cell cycle via regulating PPP2CA and p27 expression in Wilms tumor","volume":"100","author":"Cheng","year":"2022","journal-title":"Cell. Signal."},{"issue":"1","key":"10.1016\/j.placenta.2026.03.022_bib22","article-title":"KHSRP has oncogenic functions and regulates the expression and alternative splicing of DNA repair genes in breast cancer MDA-MB-231 cells","volume":"14","author":"Paizula","year":"2024","journal-title":"Sci. Rep."},{"issue":"10","key":"10.1016\/j.placenta.2026.03.022_bib23","doi-asserted-by":"crossref","first-page":"4629","DOI":"10.7150\/ijbs.111142","article-title":"Tissue factor pathway inhibitor 2 enhances hepatocellular carcinoma chemosensitivity by activating CCAR2-GADD45A-Mediated DNA damage repair","volume":"21","author":"Zhou","year":"2025","journal-title":"Int. J. Biol. Sci."},{"issue":"12","key":"10.1016\/j.placenta.2026.03.022_bib24","doi-asserted-by":"crossref","first-page":"3507","DOI":"10.1158\/1078-0432.CCR-06-3023","article-title":"Restoration of tissue factor pathway inhibitor-2 in a human glioblastoma cell line triggers caspase-mediated pathway and apoptosis","volume":"13","author":"George","year":"2007","journal-title":"Clin. Cancer Res."},{"issue":"12","key":"10.1016\/j.placenta.2026.03.022_bib25","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1038\/s41419-018-1183-8","article-title":"Long noncoding RNA AC003092.1 promotes temozolomide chemosensitivity through miR-195\/TFPI-2 signaling modulation in glioblastoma","volume":"9","author":"Xu","year":"2018","journal-title":"Cell Death Dis."},{"issue":"2","key":"10.1016\/j.placenta.2026.03.022_bib26","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.ejphar.2010.12.015","article-title":"Recombinant TFPI-2 enhances macrophage apoptosis through upregulation of Fas\/FasL","volume":"654","author":"Pan","year":"2011","journal-title":"Eur. J. Pharmacol."},{"issue":"11","key":"10.1016\/j.placenta.2026.03.022_bib27","doi-asserted-by":"crossref","first-page":"2575","DOI":"10.1111\/jog.15770","article-title":"Tissue factor pathway inhibitor 2: current understanding, challenges, and future perspectives","volume":"49","author":"Kobayashi","year":"2023","journal-title":"J. Obstet. Gynaecol. Res."},{"issue":"1","key":"10.1016\/j.placenta.2026.03.022_bib28","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1186\/s12958-023-01108-3","article-title":"Downregulated DUXAP8 lncRNA impedes trophoblast cell proliferation and migration by epigenetically upregulating TFPI2 expression","volume":"21","author":"Tang","year":"2023","journal-title":"Reprod. Biol. Endocrinol."},{"key":"10.1016\/j.placenta.2026.03.022_bib29","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.omtn.2018.05.020","article-title":"Long noncoding RNA 00473 is involved in preeclampsia by LSD1 binding-regulated TFPI2 transcription in trophoblast cells","volume":"12","author":"Wu","year":"2018","journal-title":"Mol. Ther. Nucleic Acids"},{"issue":"5","key":"10.1016\/j.placenta.2026.03.022_bib30","doi-asserted-by":"crossref","DOI":"10.1111\/cpr.12490","article-title":"MiR-616-3p modulates cell proliferation and migration through targeting tissue factor pathway inhibitor 2 in preeclampsia","volume":"51","author":"Xu","year":"2018","journal-title":"Cell Prolif."},{"issue":"5","key":"10.1016\/j.placenta.2026.03.022_bib31","doi-asserted-by":"crossref","first-page":"e251","DOI":"10.1016\/j.thromres.2009.11.026","article-title":"Involvement of heparanase in early pregnancy losses","volume":"125","author":"Nadir","year":"2010","journal-title":"Thromb. Res."},{"issue":"9","key":"10.1016\/j.placenta.2026.03.022_bib32","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1080\/15384047.2015.1070979","article-title":"Pixantrone induces cell death through mitotic perturbations and subsequent aberrant cell divisions","volume":"16","author":"Beeharry","year":"2015","journal-title":"Cancer Biol. Ther."},{"key":"10.1016\/j.placenta.2026.03.022_bib33","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.placenta.2020.10.011","article-title":"Cytogenomics of six human trophoblastic cell lines","volume":"103","author":"Weber","year":"2021","journal-title":"Placenta"},{"issue":"5","key":"10.1016\/j.placenta.2026.03.022_bib34","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1177\/1076029611429785","article-title":"Effects of tissue factor pathway inhibitor-2 expression on biological behavior of BeWo and JEG-3 cell lines","volume":"18","author":"Zhou","year":"2012","journal-title":"Clin. Appl. Thromb. Hemost."},{"issue":"D1","key":"10.1016\/j.placenta.2026.03.022_bib35","doi-asserted-by":"crossref","first-page":"D90","DOI":"10.1093\/nar\/gkv1238","article-title":"AREsite2: an enhanced database for the comprehensive investigation of AU\/GU\/U-rich elements","volume":"44","author":"Fallmann","year":"2016","journal-title":"Nucleic Acids Res."},{"issue":"1","key":"10.1016\/j.placenta.2026.03.022_bib36","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1038\/s42003-021-02214-x","article-title":"Placental secretome characterization identifies candidates for pregnancy complications","volume":"4","author":"Napso","year":"2021","journal-title":"Commun. Biol."},{"issue":"5","key":"10.1016\/j.placenta.2026.03.022_bib37","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1038\/cdd.2009.1","article-title":"Glial cell missing-1 transcription factor is required for the differentiation of the human trophoblast","volume":"16","author":"Baczyk","year":"2009","journal-title":"Cell Death Differ."},{"issue":"36","key":"10.1016\/j.placenta.2026.03.022_bib38","article-title":"Dissecting the impact of maternal androgen exposure on developmental programming through targeting the androgen receptor","volume":"11","author":"Lu","year":"2024","journal-title":"Adv. Sci. (Weinh.)"},{"issue":"12","key":"10.1016\/j.placenta.2026.03.022_bib39","doi-asserted-by":"crossref","first-page":"2083","DOI":"10.1242\/dev.020099","article-title":"Early patterning of the chorion leads to the trilaminar trophoblast cell structure in the placental labyrinth","volume":"135","author":"Simmons","year":"2008","journal-title":"Development"},{"key":"10.1016\/j.placenta.2026.03.022_bib40","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.ydbio.2023.03.009","article-title":"Gse1, a component of the CoREST complex, is required for placenta development in the mouse","volume":"498","author":"Hiver","year":"2023","journal-title":"Dev. Biol."},{"issue":"1","key":"10.1016\/j.placenta.2026.03.022_bib41","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1038\/s41467-023-36740-5","article-title":"Defects in placental syncytiotrophoblast cells are a common cause of developmental heart disease","volume":"14","author":"Radford","year":"2023","journal-title":"Nat. Commun."},{"issue":"2","key":"10.1016\/j.placenta.2026.03.022_bib42","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1093\/humupd\/dml048","article-title":"Molecular circuits shared by placental and cancer cells, and their implications in the proliferative, invasive and migratory capacities of trophoblasts","volume":"13","author":"Ferretti","year":"2007","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.placenta.2026.03.022_bib43","article-title":"Extracellular vesicles derived from human umbilical cord mesenchymal stem cells promote trophoblast cell proliferation and migration by targeting TFPI2 in preeclampsia","volume":"2023","author":"Chen","year":"2023","journal-title":"Stem Cell. Int."},{"issue":"1","key":"10.1016\/j.placenta.2026.03.022_bib44","first-page":"127","article-title":"Overexpression of tissue factor pathway inhibitor-2 (TFPI-2), decreases the invasiveness of prostate cancer cells in vitro","volume":"18","author":"Konduri","year":"2001","journal-title":"Int. J. Oncol."},{"issue":"9","key":"10.1016\/j.placenta.2026.03.022_bib45","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0073337","article-title":"Function of survivin in trophoblastic cells of the placenta","volume":"8","author":"Muschol-Steinmetz","year":"2013","journal-title":"PLoS One"},{"issue":"9","key":"10.1016\/j.placenta.2026.03.022_bib46","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.1038\/s41563-025-02269-9","article-title":"Cytoplasmic anillin and Ect2 promote RhoA\/myosin II-dependent confined migration and invasion","volume":"24","author":"Tran","year":"2025","journal-title":"Nat. Mater."},{"issue":"3","key":"10.1016\/j.placenta.2026.03.022_bib47","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbc.2021.101036","article-title":"Epithelial cell transforming factor ECT2 is an important regulator of DNA double-strand break repair and genome stability","volume":"297","author":"Cao","year":"2021","journal-title":"J. Biol. Chem."},{"issue":"6","key":"10.1016\/j.placenta.2026.03.022_bib48","doi-asserted-by":"crossref","first-page":"e317","DOI":"10.1016\/j.thromres.2010.02.017","article-title":"Changes of plasma and placental tissue factor pathway inhibitor-2 in women with preeclampsia and normal pregnancy","volume":"125","author":"Xiong","year":"2010","journal-title":"Thromb. Res."},{"issue":"4","key":"10.1016\/j.placenta.2026.03.022_bib49","doi-asserted-by":"crossref","DOI":"10.1093\/gpbjnl\/qzaf072","article-title":"The GSA family in 2025: a broadened sharing platform for multi-omics and multimodal data","volume":"23","author":"Zhang","year":"2025","journal-title":"Genom. Proteom. Bioinform."},{"issue":"D1","key":"10.1016\/j.placenta.2026.03.022_bib50","doi-asserted-by":"crossref","first-page":"D30","DOI":"10.1093\/nar\/gkae978","article-title":"Database resources of the national genomics data center, China national center for bioinformation in 2025","volume":"53","year":"2025","journal-title":"Nucleic Acids Res."}],"container-title":["Placenta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400426001074?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400426001074?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T05:42:12Z","timestamp":1779428532000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0143400426001074"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":50,"alternative-id":["S0143400426001074"],"URL":"https:\/\/doi.org\/10.1016\/j.placenta.2026.03.022","relation":{},"ISSN":["0143-4004"],"issn-type":[{"value":"0143-4004","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Trophoblast KHSRP deficiency induces DNA damage and apoptosis via TFPI2 in unexplained spontaneous miscarriage","name":"articletitle","label":"Article Title"},{"value":"Placenta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.placenta.2026.03.022","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}