{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T12:21:46Z","timestamp":1790770906395,"version":"4.1.0"},"reference-count":43,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100009633","name":"National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["HD097485"],"award-info":[{"award-number":["HD097485"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000070","name":"National Institute of Biomedical Imaging and Bioengineering","doi-asserted-by":"publisher","award":["P41EB017183"],"award-info":[{"award-number":["P41EB017183"]}],"id":[{"id":"10.13039\/100000070","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Institutes of Health National Cancer Institute","doi-asserted-by":"publisher","award":["P30CA016087"],"award-info":[{"award-number":["P30CA016087"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart Lung and Blood Institute","doi-asserted-by":"publisher","award":["HL159869"],"award-info":[{"award-number":["HL159869"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Placenta"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1016\/j.placenta.2026.05.026","type":"journal-article","created":{"date-parts":[[2026,5,23]],"date-time":"2026-05-23T15:40:35Z","timestamp":1779550835000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Contrast-agent-free visualization of murine embryo-placental vasculature with ultrafast plane-wave ultrasound"],"prefix":"10.1016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5312-7473","authenticated-orcid":false,"given":"Mark T.","family":"Burgess","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9912-135X","authenticated-orcid":false,"given":"Orlando","family":"Aristiz\u00e1bal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7175-9397","authenticated-orcid":false,"given":"Youssef Z.","family":"Wadghiri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1389-7756","authenticated-orcid":false,"given":"Jeffrey A.","family":"Ketterling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.placenta.2026.05.026_b1","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S0169-409X(99)00005-8","article-title":"Nutrient transport across the placenta","volume":"38","author":"Knipp","year":"1999","journal-title":"Adv. Drug Deliv. Rev.","ISSN":"https:\/\/id.crossref.org\/issn\/0169-409X","issn-type":"print"},{"issue":"2","key":"10.1016\/j.placenta.2026.05.026_b2","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1006\/dbio.2002.0773","article-title":"Interactions between Trophoblast Cells and the Maternal and Fetal Circulation in the Mouse Placenta","volume":"250","author":"Lee Adamson","year":"2002","journal-title":"Dev. Biol.","ISSN":"https:\/\/id.crossref.org\/issn\/0012-1606","issn-type":"print"},{"issue":"2","key":"10.1016\/j.placenta.2026.05.026_b3","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1093\/bjaceaccp\/mku013","article-title":"Placental structure, function and drug transfer","volume":"15","author":"Griffiths","year":"2015","journal-title":"Contin. Educ. Anaesth. Crit. Care & Pain","ISSN":"https:\/\/id.crossref.org\/issn\/1743-1816","issn-type":"print"},{"issue":"8","key":"10.1016\/j.placenta.2026.05.026_b4","doi-asserted-by":"crossref","first-page":"941","DOI":"10.2217\/nnm-2015-0012","article-title":"Nanoparticle transport across the placental barrier: pushing the field forward!","volume":"11","author":"Muoth","year":"2016","journal-title":"Nanomed","ISSN":"https:\/\/id.crossref.org\/issn\/1748-6963","issn-type":"print"},{"key":"10.1016\/j.placenta.2026.05.026_b5","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.placenta.2020.12.014","article-title":"Research on nanoparticles in human perfused placenta: State of the art and perspectives","volume":"104","author":"Aengenheister","year":"2021","journal-title":"Placenta","ISSN":"https:\/\/id.crossref.org\/issn\/0143-4004","issn-type":"print"},{"issue":"3","key":"10.1016\/j.placenta.2026.05.026_b6","doi-asserted-by":"crossref","first-page":"H1421","DOI":"10.1152\/ajpheart.00031.2006","article-title":"Developmental changes in hemodynamics of uterine artery, utero- and umbilicoplacental, and vitelline circulations in mouse throughout gestation","volume":"291","author":"Mu","year":"2006","journal-title":"Am. J. Physiol.-Heart Circ. Physiol.","ISSN":"https:\/\/id.crossref.org\/issn\/0363-6135","issn-type":"print"},{"issue":"2","key":"10.1016\/j.placenta.2026.05.026_b7","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1095\/biolreprod.116.140681","article-title":"Quantification of Gestational Changes in the Uteroplacental Vascular Tree Reveals Vessel Specific Hemodynamic Roles During Pregnancy in Mice","volume":"95","author":"Rennie","year":"2016","journal-title":"Biol. Reprod.","ISSN":"https:\/\/id.crossref.org\/issn\/1529-7268","issn-type":"print"},{"key":"10.1016\/j.placenta.2026.05.026_b8","doi-asserted-by":"crossref","DOI":"10.1016\/j.placenta.2026.03.011","article-title":"Emerging ultrasound-based imaging of the placenta during complications of pregnancy","author":"Shi","year":"2026","journal-title":"Placenta","ISSN":"https:\/\/id.crossref.org\/issn\/0143-4004","issn-type":"print"},{"issue":"1","key":"10.1016\/j.placenta.2026.05.026_b9","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1148\/radiol.2351040192","article-title":"Placental perfusion MR imaging with contrast agents in a mouse model","volume":"235","author":"Salomon","year":"2005","journal-title":"Radiology"},{"key":"10.1016\/j.placenta.2026.05.026_b10","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.placenta.2015.12.019","article-title":"A longitudinal study of placental perfusion using dynamic contrast enhanced magnetic resonance imaging in murine pregnancy","volume":"43","author":"Yadav","year":"2016","journal-title":"Placenta"},{"issue":"28","key":"10.1016\/j.placenta.2026.05.026_b11","doi-asserted-by":"crossref","first-page":"10353","DOI":"10.1073\/pnas.1401695111","article-title":"Major mouse placental compartments revealed by diffusion-weighted MRI, contrast-enhanced MRI, and fluorescence imaging","volume":"111","author":"Solomon","year":"2014","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"5","key":"10.1016\/j.placenta.2026.05.026_b12","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1002\/jmri.25867","article-title":"In vivo assessment of the placental anatomy and perfusion in a mouse model of intrauterine inflammation","volume":"47","author":"Wu","year":"2018","journal-title":"J. Magn. Reson. Imaging"},{"issue":"5","key":"10.1016\/j.placenta.2026.05.026_b13","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1016\/j.placenta.2013.01.019","article-title":"New insights into uteroplacental perfusion: Quantitative analysis using Doppler and contrast-enhanced ultrasound imaging","volume":"34","author":"Arthuis","year":"2013","journal-title":"Placenta","ISSN":"https:\/\/id.crossref.org\/issn\/1532-3102","issn-type":"print"},{"issue":"5","key":"10.1016\/j.placenta.2026.05.026_b14","doi-asserted-by":"crossref","DOI":"10.1098\/rsfs.2019.0024","article-title":"Longitudinal characterization of local perfusion of the rat placenta using contrast-enhanced ultrasound imaging","volume":"9","author":"Lawrence","year":"2019","journal-title":"Interface Focus."},{"issue":"4","key":"10.1016\/j.placenta.2026.05.026_b15","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0058986","article-title":"Real-Time Placental Perfusion on Contrast-Enhanced Ultrasound and Parametric Imaging Analysis in Rats at Different Gestation Time and Different Portions of Placenta","volume":"8","author":"Zhou","year":"2013","journal-title":"PLOS ONE","ISSN":"https:\/\/id.crossref.org\/issn\/1932-6203","issn-type":"print"},{"issue":"12","key":"10.1016\/j.placenta.2026.05.026_b16","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.adk1278","article-title":"Longitudinal intravital imaging of mouse placenta","volume":"10","author":"Zhu","year":"2024","journal-title":"Sci. Adv."},{"issue":"1","key":"10.1016\/j.placenta.2026.05.026_b17","doi-asserted-by":"crossref","first-page":"13394","DOI":"10.1038\/srep13394","article-title":"Discriminative imaging of maternal and fetal blood flow within the placenta using ultrafast ultrasound","volume":"5","author":"Osmanski","year":"2015","journal-title":"Sci Rep","ISSN":"https:\/\/id.crossref.org\/issn\/2045-2322","issn-type":"print"},{"issue":"6487","key":"10.1016\/j.placenta.2026.05.026_b18","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1126\/science.aba0210","article-title":"Intravital imaging of mouse embryos","volume":"368","author":"Huang","year":"2020","journal-title":"Science"},{"key":"10.1016\/j.placenta.2026.05.026_b19","doi-asserted-by":"crossref","DOI":"10.1016\/j.placenta.2026.01.019","article-title":"In vivo imaging of the rodent placenta","author":"Cahill","year":"2026","journal-title":"Placenta","ISSN":"https:\/\/id.crossref.org\/issn\/0143-4004","issn-type":"print"},{"issue":"10","key":"10.1016\/j.placenta.2026.05.026_b20","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1016\/j.ultrasmedbio.2004.07.018","article-title":"Developmental changes in integrated ultrasound backscatter from embryonic blood in vivo in mice at high US frequency","volume":"30","author":"Floc\u2019h","year":"2004","journal-title":"Ultrasound Med. Biol.","ISSN":"https:\/\/id.crossref.org\/issn\/0301-5629","issn-type":"print"},{"key":"10.1016\/j.placenta.2026.05.026_b21","doi-asserted-by":"crossref","DOI":"10.1016\/j.placenta.2026.01.020","article-title":"High sensitivity ultrasound microvessel imaging for the assessment of placental health","author":"Santos","year":"2026","journal-title":"Placenta","ISSN":"https:\/\/id.crossref.org\/issn\/0143-4004","issn-type":"print"},{"key":"10.1016\/j.placenta.2026.05.026_b22","doi-asserted-by":"crossref","DOI":"10.1016\/j.ultras.2020.106309","article-title":"So you think you can DAS? A viewpoint on delay-and-sum beamforming","volume":"111","author":"Perrot","year":"2021","journal-title":"Ultrasonics","ISSN":"https:\/\/id.crossref.org\/issn\/0041-624X","issn-type":"print"},{"issue":"11","key":"10.1016\/j.placenta.2026.05.026_b23","doi-asserted-by":"crossref","first-page":"2271","DOI":"10.1109\/TMI.2015.2428634","article-title":"Spatiotemporal Clutter Filtering of Ultrafast Ultrasound Data Highly Increases Doppler and fUltrasound Sensitivity","volume":"34","author":"Demen\u00e9","year":"2015","journal-title":"IEEE Trans. Med. Imaging","ISSN":"https:\/\/id.crossref.org\/issn\/1558-254X","issn-type":"print"},{"issue":"6","key":"10.1016\/j.placenta.2026.05.026_b24","doi-asserted-by":"crossref","first-page":"2075","DOI":"10.1109\/TUFFC.2021.3055498","article-title":"Simultaneous noise suppression and incoherent artifact reduction in ultrafast ultrasound vascular imaging","volume":"68","author":"Huang","year":"2021","journal-title":"IEEE Trans. Ultrason. Ferroelectr. Freq. Control"},{"issue":"3","key":"10.1016\/j.placenta.2026.05.026_b25","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1109\/T-SU.1985.31615","article-title":"Real-Time Two-Dimensional Blood Flow Imaging Using an Autocorrelation Technique","volume":"32","author":"Kasai","year":"1985","journal-title":"IEEE Trans. Sonics Ultrason.","ISSN":"https:\/\/id.crossref.org\/issn\/0018-9537","issn-type":"print"},{"issue":"3","key":"10.1016\/j.placenta.2026.05.026_b26","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/S0301-5629(98)00147-1","article-title":"Umbilical arterial blood flow in the mouse embryo during development and following acutely increased heart rate","volume":"25","author":"MacLennan","year":"1999","journal-title":"Ultrasound Med. Biol.","ISSN":"https:\/\/id.crossref.org\/issn\/0301-5629","issn-type":"print"},{"issue":"9","key":"10.1016\/j.placenta.2026.05.026_b27","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1161\/01.CIR.98.9.912","article-title":"In utero imaging of mouse embryonic heart development with 40-MHz echocardiography","volume":"98","author":"Srinivasan","year":"1998","journal-title":"Circulation"},{"key":"10.1016\/j.placenta.2026.05.026_b28","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1016\/S0301-5629(00)00278-7","article-title":"40 MHz Doppler characterization of umbilical and dorsal aortic blood flow in the early mouse embryo","volume":"26","author":"Phoon","year":"2000","journal-title":"Ultrasound Med. Biol."},{"issue":"6","key":"10.1016\/j.placenta.2026.05.026_b29","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1002\/mrm.22113","article-title":"Three-dimensional micro-MRI analysis of cerebral artery development in mouse embryos","volume":"62","author":"Berrios-Otero","year":"2009","journal-title":"Magn Reson. Med"},{"issue":"8","key":"10.1016\/j.placenta.2026.05.026_b30","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0002853","article-title":"Three-dimensional analysis of vascular development in the mouse embryo","volume":"3","author":"Walls","year":"2008","journal-title":"PLoS One","ISSN":"https:\/\/id.crossref.org\/issn\/1932-6203","issn-type":"print"},{"key":"10.1016\/j.placenta.2026.05.026_b31","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1038\/nature19356","article-title":"High-throughput discovery of novel developmental phenotypes","volume":"537","author":"Dickinson","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.placenta.2026.05.026_b32","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1038\/nature26002","article-title":"Placentation defects are highly prevalent in embryonic lethal mouse mutants","volume":"555","author":"Perez-Garcia","year":"2018","journal-title":"Nature"},{"key":"10.1016\/j.placenta.2026.05.026_b33","article-title":"Whole-genome sequencing of patients with rare diseases in a national health system","volume":"147","author":"Turro","year":"2020","journal-title":"Development"},{"issue":"1","key":"10.1016\/j.placenta.2026.05.026_b34","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1109\/TUFFC.2014.2882","article-title":"Ultrafast imaging in biomedical ultrasound","volume":"61","author":"Tanter","year":"2014","journal-title":"IEEE Trans. Ultrason. Ferroelectr. Freq. Control"},{"issue":"8","key":"10.1016\/j.placenta.2026.05.026_b35","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1038\/nmeth.1641","article-title":"Functional ultrasound imaging of the brain","volume":"8","author":"Mac\u00e9","year":"2011","journal-title":"Nat Methods","ISSN":"https:\/\/id.crossref.org\/issn\/1548-7105","issn-type":"print"},{"issue":"3","key":"10.1016\/j.placenta.2026.05.026_b36","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/j.zemedi.2023.02.004","article-title":"Ultrasound localization microscopy","volume":"33","author":"Dencks","year":"2023","journal-title":"Z. F\u00fcr Med. Phys.","ISSN":"https:\/\/id.crossref.org\/issn\/0939-3889","issn-type":"print"},{"issue":"1","key":"10.1016\/j.placenta.2026.05.026_b37","doi-asserted-by":"crossref","first-page":"16658","DOI":"10.1038\/s41598-017-16933-x","article-title":"Silverman. High-speed high-frequency ultrasound in utero vector-flow imaging of mouse embryos","volume":"7","author":"Ketterling","year":"2017","journal-title":"Sci Rep","ISSN":"https:\/\/id.crossref.org\/issn\/2045-2322","issn-type":"print"},{"issue":"1","key":"10.1016\/j.placenta.2026.05.026_b38","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.ultrasmedbio.2022.09.008","article-title":"Longitudinal in Utero Analysis of Engrailed-1 Knockout Mouse Embryonic Phenotypes Using High-Frequency Ultrasound","volume":"49","author":"Aristiz\u00e1bal","year":"2023","journal-title":"Ultrasound Med. Biol."},{"issue":"3","key":"10.1016\/j.placenta.2026.05.026_b39","article-title":"Effects of isoflurane anesthesia on the cardiovascular function of the c57bl\/6 mouse","volume":"52","author":"Constantinides","year":"2011","journal-title":"ILAR J."},{"issue":"1","key":"10.1016\/j.placenta.2026.05.026_b40","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1038\/sj.mt.6300332","article-title":"Efficient in vivo targeting of epidermal stem cells by early gestational intraamniotic injection of lentiviral vector driven by the keratin 5 promoter","volume":"16","author":"Endo","year":"2008","journal-title":"Mol. Ther."},{"key":"10.1016\/j.placenta.2026.05.026_b41","doi-asserted-by":"crossref","first-page":"3759","DOI":"10.1242\/dev.128.19.3759","article-title":"In utero fate mapping reveals distinct migratory pathways and fates of neurons born in the mammalian basal forebrain","volume":"128","author":"Wichterle","year":"2001","journal-title":"Development"},{"issue":"1\u20132","key":"10.1016\/j.placenta.2026.05.026_b42","first-page":"107","article-title":"Alteration of limb and brain patterning in early mouse embryos by ultrasound-guided injection of Shh-expressing cells","volume":"75","author":"Liu","year":"1998","journal-title":"MOD"},{"key":"10.1016\/j.placenta.2026.05.026_b43","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/1471-213X-6-10","article-title":"High resolution ultrasound-guided microinjection for interventional studies of early embryonic and placental development in vivo in mice","volume":"6","author":"Slevin","year":"2006","journal-title":"BMC Dev. Biol."}],"container-title":["Placenta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400426001888?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400426001888?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T18:00:59Z","timestamp":1783188059000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0143400426001888"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":43,"alternative-id":["S0143400426001888"],"URL":"https:\/\/doi.org\/10.1016\/j.placenta.2026.05.026","relation":{},"ISSN":["0143-4004"],"issn-type":[{"value":"0143-4004","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Contrast-agent-free visualization of murine embryo-placental vasculature with ultrafast plane-wave ultrasound","name":"articletitle","label":"Article Title"},{"value":"Placenta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.placenta.2026.05.026","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}