{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T16:54:49Z","timestamp":1792169689502,"version":"4.4.0"},"reference-count":17,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Placenta"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.placenta.2026.08.338","type":"journal-article","created":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T22:39:55Z","timestamp":1787438395000},"page":"144-151","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Ginkgolide B alleviates placental inflammation and ferroptosis in gestational diabetes through inhibition of the NLRP3 inflammasome and activation of Nrf2\/HO-1 signaling"],"prefix":"10.1016","volume":"183","author":[{"given":"Yan","family":"Cao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.placenta.2026.08.338_bib1","doi-asserted-by":"crossref","DOI":"10.1155\/2018\/4207067","article-title":"Higher concentrations of BCAAs and 3-HIB are associated with insulin resistance in the transition from gestational diabetes to type 2 diabetes","volume":"2018","author":"Andersson-Hall","year":"2018","journal-title":"J. Diabetes Res."},{"key":"10.1016\/j.placenta.2026.08.338_bib2","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1159\/000521080","article-title":"Asperulosidic acid, a bioactive iridoid, alleviates placental oxidative stress and inflammatory responses in gestational diabetes mellitus by suppressing NF-kappaB and MAPK signaling pathways","volume":"107","author":"Wu","year":"2022","journal-title":"Pharmacology"},{"key":"10.1016\/j.placenta.2026.08.338_bib3","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1186\/s41065-025-00465-w","article-title":"Astragaloside IV regulates FOXM1 deubiquitination to ameliorate trophoblast damage caused by high glucose","volume":"162","author":"Li","year":"2025","journal-title":"Hereditas"},{"key":"10.1016\/j.placenta.2026.08.338_bib4","doi-asserted-by":"crossref","DOI":"10.2478\/aite-2025-0006","article-title":"Isorhynchophylline inhibits NLRP3 inflammasome and improves gestational diabetes","volume":"73","author":"Pu","year":"2025","journal-title":"Arch. Immunol. Ther. Exp."},{"key":"10.1016\/j.placenta.2026.08.338_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2025.114057","article-title":"Urolithin A alleviates NLRP3 inflammasome activation and pyroptosis by promoting microglial mitophagy following spinal cord injury","volume":"148","author":"Chen","year":"2025","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.placenta.2026.08.338_bib6","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.1021\/acs.jafc.4c07635","article-title":"Ganoderic acid A alleviates severe acute pancreatitis by modulating gut homeostasis and inhibiting TLR4-NLRP3 signaling","volume":"73","author":"Zhang","year":"2025","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.placenta.2026.08.338_bib7","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1111\/cns.13657","article-title":"Zinc attenuates ferroptosis and promotes functional recovery in contusion spinal cord injury by activating Nrf2\/GPX4 defense pathway","volume":"27","author":"Ge","year":"2021","journal-title":"CNS Neurosci. Ther."},{"key":"10.1016\/j.placenta.2026.08.338_bib8","doi-asserted-by":"crossref","DOI":"10.3892\/ijmm.2026.5746","article-title":"Ginkgolide C alleviates atherosclerosis via activating Nrf2 to inhibit ROS-dependent NLRP3 inflammasome activation","volume":"57","author":"Zhang","year":"2026","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.placenta.2026.08.338_bib9","doi-asserted-by":"crossref","DOI":"10.1002\/iid3.70364","article-title":"Ginkgolide B alleviates airway inflammation in hyperoxia lung injury","volume":"14","author":"Wang","year":"2026","journal-title":"Immunity, inflammation and disease"},{"key":"10.1016\/j.placenta.2026.08.338_bib10","volume":"106","author":"Zhong","year":"2025"},{"key":"10.1016\/j.placenta.2026.08.338_bib11","article-title":"Ginkgolide B effectively mitigates neuropathic pain by suppressing the activation of the NLRP3 inflammasome through the induction of mitophagy in rats","volume":"177","author":"Liang","year":"2024","journal-title":"Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie"},{"key":"10.1016\/j.placenta.2026.08.338_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.taap.2025.117237","article-title":"Ginkgolide B binds to GPX4 and FSP1 to alleviate cerebral ischemia\/reperfusion injury in rats","volume":"495","author":"Zou","year":"2025","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.placenta.2026.08.338_bib13","doi-asserted-by":"crossref","first-page":"8309","DOI":"10.2147\/DDDT.S541290","article-title":"Ginkgolide B alleviates LPS-induced inhibition of osteogenic differentiation in human periodontal ligament stem cells by suppressing the p-IkappaBalpha\/NF-kappaB pathway","volume":"19","author":"Du","year":"2025","journal-title":"Drug Des. Dev. Ther."},{"key":"10.1016\/j.placenta.2026.08.338_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcp.2026.117733","article-title":"Ginkgolide B alleviates diabetic retinopathy by inhibiting ferroptosis in retinal vascular endothelial cells via the TSPO\/Nrf2 pathway","volume":"246","author":"Lu","year":"2026","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.placenta.2026.08.338_bib15","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1007\/s12272-020-01242-1","article-title":"Cryptotanshinone ameliorates placental oxidative stress and inflammation in mice with gestational diabetes mellitus","volume":"43","author":"Wang","year":"2020","journal-title":"Arch Pharm. Res. (Seoul)"},{"key":"10.1016\/j.placenta.2026.08.338_bib16","doi-asserted-by":"crossref","DOI":"10.1002\/jbt.22904","article-title":"Myrtenol alleviates oxidative stress and inflammation in diabetic pregnant rats via TLR4\/MyD88\/NF-kappaB signaling pathway","volume":"35","author":"Xuemei","year":"2021","journal-title":"J. Biochem. Mol. Toxicol."},{"key":"10.1016\/j.placenta.2026.08.338_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2024.117887","article-title":"Ginkgolide C inhibits ROS-mediated activation of NLRP3 inflammasome in chondrocytes to ameliorate osteoarthritis","volume":"325","author":"Jia","year":"2024","journal-title":"J. Ethnopharmacol."}],"container-title":["Placenta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400426006715?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400426006715?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T16:38:43Z","timestamp":1792168723000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0143400426006715"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":17,"alternative-id":["S0143400426006715"],"URL":"https:\/\/doi.org\/10.1016\/j.placenta.2026.08.338","relation":{},"ISSN":["0143-4004"],"issn-type":[{"value":"0143-4004","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Ginkgolide B alleviates placental inflammation and ferroptosis in gestational diabetes through inhibition of the NLRP3 inflammasome and activation of Nrf2\/HO-1 signaling","name":"articletitle","label":"Article Title"},{"value":"Placenta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.placenta.2026.08.338","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}