{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T15:44:44Z","timestamp":1792511084395,"version":"4.5.0"},"reference-count":49,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T00:00:00Z","timestamp":1786060800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012246","name":"Priority Academic Program Development of Jiangsu Higher Education Institutions","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012246","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32272756"],"award-info":[{"award-number":["32272756"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32430096"],"award-info":[{"award-number":["32430096"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Plant Physiology and Biochemistry"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.plaphy.2026.111634","type":"journal-article","created":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T23:35:59Z","timestamp":1786145759000},"page":"111634","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["CmPP6 and CmMIEL1 interact with CmBBX7 to regulate flowering time in chrysanthemum"],"prefix":"10.1016","volume":"238","author":[{"given":"Yuqing","family":"Zhu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinyu","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiwen","family":"Zhai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lixia","family":"Qin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weimin","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fadi","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiafu","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.plaphy.2026.111634_bib1","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1111\/pbi.13201","article-title":"An apple MYB transcription factor regulates cold tolerance and anthocyanin accumulation and undergoes MIEL1-mediated degradation","volume":"18","author":"An","year":"2020","journal-title":"Plant Biotechnol. J."},{"key":"10.1016\/j.plaphy.2026.111634_bib2","doi-asserted-by":"crossref","first-page":"2707","DOI":"10.1111\/nph.17050","article-title":"Apple B-box protein BBX37 regulates jasmonic acid mediated cold tolerance through the JAZ-BBX37-ICE1-CBF pathway and undergoes MIEL1-mediated ubiquitination and degradation","volume":"229","author":"An","year":"2021","journal-title":"New Phytol."},{"key":"10.1016\/j.plaphy.2026.111634_bib3","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1139\/cjps-2018-0154","article-title":"Constitutive expression of chrysanthemum CmBBX29 delays flowering time in transgenic Arabidopsis","volume":"100","author":"Chen","year":"2020","journal-title":"Can. J. Plant Sci."},{"key":"10.1016\/j.plaphy.2026.111634_bib4","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1093\/plphys\/kiab420","article-title":"Zinc-finger protein MdBBX7\/MdCOL9, a target of MdMIEL1 E3 ligase, confers drought tolerance in apple","volume":"188","author":"Chen","year":"2022","journal-title":"Plant Physiol."},{"key":"10.1016\/j.plaphy.2026.111634_bib5","doi-asserted-by":"crossref","first-page":"1652","DOI":"10.1111\/tpj.16453","article-title":"The RAV transcription factor TEMPRANILLO1 involved in ethylene-mediated delay of chrysanthemum flowering","volume":"116","author":"Cheng","year":"2023","journal-title":"Plant J."},{"key":"10.1016\/j.plaphy.2026.111634_bib6","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1111\/pce.14488","article-title":"An ethylene-responsive transcription factor and a B-box protein coordinate vegetative growth and photoperiodic flowering in chrysanthemum","volume":"46","author":"Cheng","year":"2023","journal-title":"Plant Cell Environ."},{"key":"10.1016\/j.plaphy.2026.111634_bib7","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/j.molp.2023.01.010","article-title":"Ca(2+)-dependent TaCCD1 cooperates with TaSAUR215 to enhance plasma membrane H(+)-ATPase activity and alkali stress tolerance by inhibiting PP2C-mediated dephosphorylation of TaHA2 in wheat","volume":"16","author":"Cui","year":"2023","journal-title":"Mol. Plant"},{"key":"10.1016\/j.plaphy.2026.111634_bib8","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1105\/tpc.112.105767","article-title":"The PP6 phosphatase regulates ABI5 phosphorylation and abscisic acid signaling in Arabidopsis","volume":"25","author":"Dai","year":"2013","journal-title":"Plant Cell"},{"key":"10.1016\/j.plaphy.2026.111634_bib9","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1111\/nph.70513","article-title":"A U-box E3 ubiquitin ligase CmPUB15 targets CmMYB73 to regulate anthocyanin biosynthesis in response to low temperatures in chrysanthemum","volume":"248","author":"Geng","year":"2025","journal-title":"New Phytol."},{"key":"10.1016\/j.plaphy.2026.111634_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.xplc.2025.101457","article-title":"The multifaceted roles of PP2C phosphatases in plant growth, signaling, and responses to abiotic and biotic stresses","volume":"6","author":"Ghanizadeh","year":"2025","journal-title":"Plant Commun."},{"key":"10.1016\/j.plaphy.2026.111634_bib11","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1038\/s41438-021-00525-y","article-title":"Overexpression of the CmJAZ1-like gene delays flowering in Chrysanthemum morifolium","volume":"8","author":"Guan","year":"2021","journal-title":"Hortic. Res."},{"key":"10.1016\/j.plaphy.2026.111634_bib12","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/bs.mie.2016.09.030","article-title":"Posttranslational modifications and plant-environment interaction","volume":"586","author":"Hashiguchi","year":"2017","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.plaphy.2026.111634_bib13","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1270\/jsbbs.17084","article-title":"Florigen and anti-florigen: flowering regulation in horticultural crops","volume":"68","author":"Higuchi","year":"2018","journal-title":"Breed. Sci."},{"key":"10.1016\/j.plaphy.2026.111634_bib14","doi-asserted-by":"crossref","first-page":"2192","DOI":"10.1093\/jxb\/eraf019","article-title":"Late flowering in chrysanthemum induced by low ambient temperature is mediated by FLOWERING LOCUS C-like","volume":"76","author":"Hu","year":"2025","journal-title":"J. Exp. Bot."},{"key":"10.1016\/j.plaphy.2026.111634_bib15","first-page":"369","article-title":"Chemical control of flowering time","volume":"68","author":"Ionescu","year":"2017","journal-title":"J. Exp. Bot."},{"key":"10.1016\/j.plaphy.2026.111634_bib16","first-page":"1","article-title":"Post-Translational control of TaFT1 by WAPO1 ubiquitination shapes spike architecture and yield in wheat","author":"Jiang","year":"2026","journal-title":"Plant Biotechnol. J."},{"key":"10.1016\/j.plaphy.2026.111634_bib17","doi-asserted-by":"crossref","first-page":"3043","DOI":"10.1105\/tpc.005306","article-title":"A phytochrome-associated protein phosphatase 2A modulates light signals in flowering time control in Arabidopsis","volume":"14","author":"Kim","year":"2002","journal-title":"Plant Cell"},{"issue":"14","key":"10.1016\/j.plaphy.2026.111634_bib18","doi-asserted-by":"crossref","first-page":"4508","DOI":"10.1093\/jxb\/erag152","article-title":"A reciprocal feedback loop between general regulatory factor 9 and SNF1-related protein kinase 1 integrates shade signaling with autophagy-mediated flower bud abortion in lotus","volume":"77","author":"Kuang","year":"2026","journal-title":"J. Exp. Bot."},{"key":"10.1016\/j.plaphy.2026.111634_bib19","doi-asserted-by":"crossref","first-page":"2040","DOI":"10.1093\/pcp\/pcx116","article-title":"The MIEL1 E3 ubiquitin ligase negatively regulates cuticular wax biosynthesis in arabidopsis stems","volume":"58","author":"Lee","year":"2017","journal-title":"Plant Cell Physiol."},{"key":"10.1016\/j.plaphy.2026.111634_bib20","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/j.devcel.2024.10.014","article-title":"Dephosphorylation of bZIP59 by PP2A ensures appropriate shade avoidance response in Arabidopsis","volume":"60","author":"Li","year":"2025","journal-title":"Dev. Cell"},{"key":"10.1016\/j.plaphy.2026.111634_bib21","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1007\/978-1-0716-1625-3_3","article-title":"Protein phosphorylation in plant cell signaling","volume":"2358","author":"Li","year":"2021","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.plaphy.2026.111634_bib22","doi-asserted-by":"crossref","DOI":"10.1093\/plcell\/koaf269","article-title":"The peptide CmGAST1 integrates calcium and gibberellin signaling to regulate flowering in chrysanthemum","volume":"37","author":"Liu","year":"2025","journal-title":"Plant Cell"},{"key":"10.1016\/j.plaphy.2026.111634_bib23","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1093\/plphys\/kiae109","article-title":"Flowering time: from physiology, through genetics to mechanism","volume":"195","author":"Maple","year":"2024","journal-title":"Plant Physiol."},{"key":"10.1016\/j.plaphy.2026.111634_bib24","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.1038\/ncomms2479","article-title":"Arabidopsis ubiquitin ligase MIEL1 mediates degradation of the transcription factor MYB30 weakening plant defence","volume":"4","author":"Marino","year":"2013","journal-title":"Nat. Commun."},{"key":"10.1016\/j.plaphy.2026.111634_bib25","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1038\/s41467-019-09341-4","article-title":"Addendum: arabidopsis ubiquitin ligase MIEL1 mediates degradation of the transcription factor MYB30 weakening plant defence","volume":"10","author":"Marino","year":"2019","journal-title":"Nat. Commun."},{"key":"10.1016\/j.plaphy.2026.111634_bib26","doi-asserted-by":"crossref","DOI":"10.3390\/ijms22020975","article-title":"The protein Phosphatase PP2A plays multiple roles in plant development by regulation of vesicle traffic-facts and questions","volume":"22","author":"Mathe","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.plaphy.2026.111634_bib27","doi-asserted-by":"crossref","first-page":"E8528","DOI":"10.1073\/pnas.1704189114","article-title":"BPM-CUL3 E3 ligase modulates thermotolerance by facilitating negative regulatory domain-mediated degradation of DREB2A in Arabidopsis","volume":"114","author":"Morimoto","year":"2017","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.plaphy.2026.111634_bib28","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1111\/jipb.13234","article-title":"The MIEL1-ABI5\/MYB30 regulatory module fine tunes abscisic acid signaling during seed germination","volume":"64","author":"Nie","year":"2022","journal-title":"J. Integr. Plant Biol."},{"key":"10.1016\/j.plaphy.2026.111634_bib29","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/j.plaphy.2019.10.019","article-title":"The heterologous expression in Arabidopsis thaliana of a chrysanthemum gene encoding the BBX family transcription factor CmBBX13 delays flowering","volume":"144","author":"Ping","year":"2019","journal-title":"Plant Physiol. Biochem."},{"key":"10.1016\/j.plaphy.2026.111634_bib30","doi-asserted-by":"crossref","first-page":"1514","DOI":"10.1111\/jipb.13281","article-title":"PP2A interacts with KATANIN to promote microtubule organization and conical cell morphogenesis","volume":"64","author":"Ren","year":"2022","journal-title":"J. Integr. Plant Biol."},{"key":"10.1016\/j.plaphy.2026.111634_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.indcrop.2024.118568","article-title":"Identification and function analysis of PP2C gene family shows that BnaA2.PP2C73 negatively regulates drought and salt stress responses in Brassica napus L","volume":"214","author":"Ruan","year":"2024","journal-title":"Ind. Crop. Prod."},{"key":"10.1016\/j.plaphy.2026.111634_bib32","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1111\/tpj.13022","article-title":"Phosphorylation of CONSTANS and its COP1-dependent degradation during photoperiodic flowering of Arabidopsis","volume":"84","author":"Sarid-Krebs","year":"2015","journal-title":"Plant J."},{"key":"10.1016\/j.plaphy.2026.111634_bib33","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1038\/nmeth.2519","article-title":"Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation","volume":"10","author":"Swaney","year":"2013","journal-title":"Nat. Methods"},{"key":"10.1016\/j.plaphy.2026.111634_bib34","doi-asserted-by":"crossref","DOI":"10.1093\/plcell\/koaf276","article-title":"Phosphorylation and ubiquitination synergistically promote the degradation of OsRbohB to modulate rice immunity","volume":"37","author":"Tao","year":"2025","journal-title":"Plant Cell"},{"key":"10.1016\/j.plaphy.2026.111634_bib35","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1016\/j.tplants.2018.09.004","article-title":"Protein language: post-translational modifications talking to each other","volume":"23","author":"Vu","year":"2018","journal-title":"Trends Plant Sci."},{"key":"10.1016\/j.plaphy.2026.111634_bib36","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1016\/j.hpj.2023.09.012","article-title":"CmNLP7 interacts with CmPP6 to suppress flowering time in Chrysanthemum","volume":"11","author":"Wang","year":"2025","journal-title":"Hortic. Plant J."},{"key":"10.1016\/j.plaphy.2026.111634_bib37","doi-asserted-by":"crossref","first-page":"2923","DOI":"10.1111\/pce.14919","article-title":"Two B-box proteins orchestrate vegetative and reproductive growth in summer chrysanthemum","volume":"47","author":"Wang","year":"2024","journal-title":"Plant Cell Environ."},{"key":"10.1016\/j.plaphy.2026.111634_bib38","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1038\/s41467-017-00812-0","article-title":"Control of chrysanthemum flowering through integration with an aging pathway","volume":"8","author":"Wei","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.plaphy.2026.111634_bib39","doi-asserted-by":"crossref","DOI":"10.1093\/plcell\/koaf032","article-title":"The maize GSK3-like kinase ZmSK1 negatively regulates drought tolerance by phosphorylating the transcription factor ZmCPP2","volume":"37","author":"Xiang","year":"2025","journal-title":"Plant Cell"},{"key":"10.1016\/j.plaphy.2026.111634_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.plaphy.2024.108726","article-title":"CsMIEL1 effectively inhibits the accumulation of anthocyanins under low temperatures in tea plants (Camelliasinensis)","volume":"211","author":"Xing","year":"2024","journal-title":"Plant Physiol. Biochem."},{"key":"10.1016\/j.plaphy.2026.111634_bib41","doi-asserted-by":"crossref","first-page":"2038","DOI":"10.1105\/tpc.114.124867","article-title":"A zinc finger protein regulates flowering time and abiotic stress tolerance in chrysanthemum by Modulating Gibberellin biosynthesis","volume":"26","author":"Yang","year":"2014","journal-title":"Plant Cell"},{"key":"10.1016\/j.plaphy.2026.111634_bib42","doi-asserted-by":"crossref","first-page":"2573","DOI":"10.1093\/plphys\/kiad502","article-title":"Rose long noncoding RNA lncWD83 promotes flowering by modulating ubiquitination of the floral repressor RcMYC2L","volume":"193","author":"Yeqing","year":"2023","journal-title":"Plant Physiol."},{"key":"10.1016\/j.plaphy.2026.111634_bib43","doi-asserted-by":"crossref","first-page":"20218","DOI":"10.1073\/pnas.1907540116","article-title":"Arabidopsis PP6 phosphatases dephosphorylate PIF proteins to repress photomorphogenesis","volume":"116","author":"Yu","year":"2019","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.plaphy.2026.111634_bib44","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/s43897-023-00055-2","article-title":"BBX7 interacts with BBX8 to accelerate flowering in chrysanthemum","volume":"3","author":"Zhai","year":"2023","journal-title":"Mol. Horticult."},{"key":"10.1016\/j.plaphy.2026.111634_bib45","doi-asserted-by":"crossref","first-page":"3562","DOI":"10.1093\/plcell\/koae167","article-title":"Phosphorylated transcription factor PuHB40 mediates ROS-dependent anthocyanin biosynthesis in pear exposed to high light","volume":"36","author":"Zhang","year":"2024","journal-title":"Plant Cell"},{"key":"10.1016\/j.plaphy.2026.111634_bib46","article-title":"Protein phosphorylation: a molecular switch in plant signaling","volume":"42","author":"Zhang","year":"2023","journal-title":"Cell Rep."},{"key":"10.1016\/j.plaphy.2026.111634_bib47","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1111\/jipb.13826","article-title":"Apple MIEL1\/ABI5-MAX2 regulatory module links strigolactone and abscisic acid signals","volume":"67","author":"Zhang","year":"2025","journal-title":"J. Integr. Plant Biol."},{"key":"10.1016\/j.plaphy.2026.111634_bib48","doi-asserted-by":"crossref","first-page":"2413","DOI":"10.1093\/plphys\/kiad476","article-title":"Flowering repressor CmSVP recruits the TOPLESS corepressor to control flowering in chrysanthemum","volume":"193","author":"Zhang","year":"2023","journal-title":"Plant Physiol."},{"key":"10.1016\/j.plaphy.2026.111634_bib49","doi-asserted-by":"crossref","first-page":"2848","DOI":"10.1093\/plphys\/kiad503","article-title":"PHOTOLYASE\/BLUE LIGHT RECEPTOR2 regulates chrysanthemum flowering by compensating for gibberellin perception","volume":"193","author":"Zhao","year":"2023","journal-title":"Plant Physiol."}],"container-title":["Plant Physiology and Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0981942826006200?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0981942826006200?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T15:00:38Z","timestamp":1792508438000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0981942826006200"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":49,"alternative-id":["S0981942826006200"],"URL":"https:\/\/doi.org\/10.1016\/j.plaphy.2026.111634","relation":{},"ISSN":["0981-9428"],"issn-type":[{"value":"0981-9428","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"CmPP6 and CmMIEL1 interact with CmBBX7 to regulate flowering time in chrysanthemum","name":"articletitle","label":"Article Title"},{"value":"Plant Physiology and Biochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.plaphy.2026.111634","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Masson SAS.","name":"copyright","label":"Copyright"}],"article-number":"111634"}}