{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T20:08:02Z","timestamp":1790626082280,"version":"4.1.0"},"reference-count":44,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T00:00:00Z","timestamp":1786924800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Plant Physiology and Biochemistry"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.plaphy.2026.111663","type":"journal-article","created":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T23:10:48Z","timestamp":1787008248000},"page":"111663","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["MdMYB70 transcription factor modulates malate accumulation under drought stress in apple"],"prefix":"10.1016","volume":"238","author":[{"given":"Ping","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shixiong","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zonghuan","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenfang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Mao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6963-1279","authenticated-orcid":false,"given":"Baihong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.plaphy.2026.111663_bib1","first-page":"307","article-title":"MYB transcription factor genes as regulators for plant responses: an overview","volume":"19","author":"Ambawat","year":"2013","journal-title":"PhysiolMolBiolPla"},{"key":"10.1016\/j.plaphy.2026.111663_bib2","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1002\/jsfa.4270","article-title":"Sensory characterisation enabled the first classification of dessert bananas","volume":"91","author":"Bugaud","year":"2011","journal-title":"J. Sci. FoodAgr."},{"key":"10.1016\/j.plaphy.2026.111663_bib3","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.plaphy.2019.01.024","article-title":"Advance of the negative regulation of anthocyanin biosynthesis by MYB transcription factors","volume":"136","author":"Chen","year":"2019","journal-title":"Plant. Physio. lBioch"},{"key":"10.1016\/j.plaphy.2026.111663_bib4","doi-asserted-by":"crossref","first-page":"tpab027","DOI":"10.1093\/treephys\/tpab027","article-title":"Metabolic responses of date palm (Phoenix dactyliferaL.) leaves to drought differ in summer and winter climate","volume":"41","author":"Du","year":"2021","journal-title":"Tree Physiol."},{"key":"10.1016\/j.plaphy.2026.111663_bib5","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1093\/jxb\/ert035","article-title":"What controls fleshy fruit acidity? A review of malate and citrate accumulation in fruit cells","volume":"64","author":"Etienne","year":"2013","journal-title":"J. Exp. Bot."},{"key":"10.1016\/j.plaphy.2026.111663_bib6","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.foodchem.2017.01.014","article-title":"Variation of ascorbic acid concentration in fruits of cultivated and wild apples","volume":"225","author":"Fang","year":"2017","journal-title":"Food Chem."},{"key":"10.1016\/j.plaphy.2026.111663_bib7","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.celrep.2013.12.009","article-title":"Hyper acidification of vacuoles by the combine daction of two different P-ATPases in the tonoplast determines flower color","volume":"6","author":"Faraco","year":"2014","journal-title":"Cell Rep."},{"key":"10.1016\/j.plaphy.2026.111663_bib8","doi-asserted-by":"crossref","first-page":"47","DOI":"10.3410\/B1-47","article-title":"The role of malate in plant homeostasis","volume":"1","author":"Finkemeier","year":"2009","journal-title":"F1000 Biol. Rep."},{"key":"10.1016\/j.plaphy.2026.111663_bib9","doi-asserted-by":"crossref","first-page":"uhab053","DOI":"10.1093\/hr\/uhab053","article-title":"Overexpression of the apple Ma12, amitochondrial pyrophosphatase pump gene, leads to malic acid accumulation and the upregulation of malate dehydrogenase in tomato and apple calli","volume":"9","author":"Gao","year":"2022","journal-title":"Hortic. Res."},{"key":"10.1016\/j.plaphy.2026.111663_bib10","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1111\/tpj.13579","article-title":"The R2R3-MYB transcription factor MdMYB73 is involved in malateaccumulation and vacuolar acidification in apple","volume":"91","author":"Hu","year":"2017","journal-title":"Plant J."},{"key":"10.1016\/j.plaphy.2026.111663_bib11","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1104\/pp.15.01333","article-title":"MdMYB1 regulates anthocyanin and malate accumulation by directly facilitating their transport into vacuoles in apples","volume":"170","author":"Hu","year":"2016","journal-title":"Plant Physiol."},{"key":"10.1016\/j.plaphy.2026.111663_bib12","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1007\/s00299-015-1914-6","article-title":"MdSOS2L1 phosphorylates MdVHA-B1 to modulate malate accumulation in response to salinity in apple","volume":"35","author":"Hu","year":"2016","journal-title":"Plant Cell Rep."},{"key":"10.1016\/j.plaphy.2026.111663_bib13","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1111\/tpj.13957","article-title":"Apple fruit acidity is genetically diversified by natural variations in three hierarchical epistatic genes MdSAUR37, MdPP2CH and MdALMTII","volume":"95","author":"Jia","year":"2018","journal-title":"Plant J."},{"key":"10.1016\/j.plaphy.2026.111663_bib14","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1093\/plphys\/kiab098","article-title":"Genetic variation in the promoter of an R2R3\u2013MYB transcription factor determines fruit malate content in apple (Malus domestica Borkh.)","volume":"186","author":"Jia","year":"2021","journal-title":"Plant Physiol."},{"key":"10.1016\/j.plaphy.2026.111663_bib15","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1104\/pp.107.110981","article-title":"Overexpression of AtMYB44enhances stomatal closure to confer abiotic stress tolerance in transgenic Arabidopsis","volume":"146","author":"Jung","year":"2008","journal-title":"Plant Physiol."},{"key":"10.1016\/j.plaphy.2026.111663_bib16","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.21273\/HORTSCI.46.8.1163","article-title":"Early navel orange fruityield, quality, and maturity in response to late-season water stress","volume":"46","author":"Kallsen","year":"2011","journal-title":"Hortscience"},{"key":"10.1016\/j.plaphy.2026.111663_bib17","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1007\/s11295-012-0571-y","article-title":"Differences in acidity of apples are probably mainly caused by a malic acid transporter gene on LG16","volume":"9","author":"Khan","year":"2013","journal-title":"Tree Genet. Genomes"},{"key":"10.1016\/j.plaphy.2026.111663_bib18","first-page":"909","article-title":"Effects of different irrigation methods and regimes on vegetative growth, fruit yield and quality of apple trees","volume":"23","author":"Koksal","year":"1999","journal-title":"Turkish J. AgrIC. Forestry Sci."},{"key":"10.1016\/j.plaphy.2026.111663_bib19","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1111\/j.1365-313X.2007.03367.x","article-title":"The Arabidopsis vacuolarmalate channel is a member of the ALMT family","volume":"52","author":"Kovermann","year":"2007","journal-title":"Plant J."},{"key":"10.1016\/j.plaphy.2026.111663_bib20","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/s00299-002-0492-6","article-title":"Agrobacterium-mediated transformation of embryogenic calluses of Ponkan mandarin and the regeneration of plants containing the chimeric ribonuclease gene","volume":"21","author":"Li","year":"2002","journal-title":"Plant Cell Rep."},{"key":"10.1016\/j.plaphy.2026.111663_bib21","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1038\/s41438-018-0064-8","article-title":"Sugar metabolism and accumulation in the fruit of transgenic apple trees with decreased sorbitol synthesis","volume":"5","author":"Li","year":"2018","journal-title":"Hortic. Res."},{"key":"10.1016\/j.plaphy.2026.111663_bib22","doi-asserted-by":"crossref","first-page":"3419","DOI":"10.1093\/jxb\/erx187","article-title":"Citrus CitNAC62 cooperates with CitWRKY1 to participate in citric acid degradation via up-regulation of CitAco3","volume":"68","author":"Li","year":"2017","journal-title":"J. Exp. Bot."},{"key":"10.1016\/j.plaphy.2026.111663_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2025.142332","article-title":"Transcription factor MdNAC18.1 regulates malic acid accumulation in apple fruits","volume":"308","author":"Liu","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.plaphy.2026.111663_bib24","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1111\/nph.12687","article-title":"Drought enhances folivory by shifting foliar metabolomes in Quercus ilex trees","volume":"202","author":"Mateu-Castell","year":"2014","journal-title":"New Phytol."},{"key":"10.1016\/j.plaphy.2026.111663_bib25","doi-asserted-by":"crossref","first-page":"1993","DOI":"10.1093\/jxb\/ery054","article-title":"Ammonium intensifies CAM photosynthesis and counteracts drought effects by increasing malate transport and antioxidant capacity in Guzmaniamonostachia","volume":"8","author":"Pereira","year":"2018","journal-title":"J. Exp. Bot."},{"key":"10.1016\/j.plaphy.2026.111663_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.envexpbot.2021.104523","article-title":"MdCIB1, an apple bHLH transcription factor, plays a positive regulator in response to drought stress","volume":"188","author":"Ren","year":"2021","journal-title":"Environ. Exp. Bot."},{"key":"10.1016\/j.plaphy.2026.111663_bib27","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/s00709-010-0169-x","article-title":"Antioxidant response of wheat roots to drought acclimation","volume":"245","author":"Selote","year":"2010","journal-title":"Protoplasma"},{"issue":"3","key":"10.1016\/j.plaphy.2026.111663_bib28","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/S1369-5266(00)80068-0","article-title":"Molecular responses to dehydration and low temperature: differences and cross-talk between two stress signaling pathways","volume":"3","author":"Shinozaki","year":"2000","journal-title":"Curr. Opin. Plant Biol."},{"key":"10.1016\/j.plaphy.2026.111663_bib29","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1093\/pcp\/pci251","article-title":"A highly efficient transformation protocol for micro-tom, a model cultivar for tomato functional genomics","volume":"47","author":"Sun","year":"2006","journal-title":"Plant Cell Physiol."},{"key":"10.1016\/j.plaphy.2026.111663_bib30","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1016\/j.phytochem.2009.08.006","article-title":"Regulation of malate metabolism in grape berry and other developing fruits","volume":"70","author":"Sweetman","year":"2009","journal-title":"Phytochemistry"},{"key":"10.1016\/j.plaphy.2026.111663_bib31","first-page":"112","article-title":"Responses of \u2018Spring Bright\u2019 and \u2018Summer Bright\u2019 nectarines to deficit irrigation: fruit growth and concentration of sugars and organic acids","volume":"135","author":"Thakur","year":"2012","journal-title":"SciHortic"},{"key":"10.1016\/j.plaphy.2026.111663_bib32","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1007\/s10341-016-0277-7","article-title":"Effects of irrigation frequency on yield and quality parameters in apple c","volume":"58","author":"Ucar","year":"2016","journal-title":"v. \u2018Gala, galaxy\u2019.Erwerbs-Obstbau"},{"key":"10.1016\/j.plaphy.2026.111663_bib33","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1111\/nph.70259","article-title":"MdARF2-mediated ABA signaling orchestrates malate biosynthesis and transport via repression of MdcyMDH and MdMATEL1 in apple","volume":"247","author":"Wang","year":"2025","journal-title":"New Phytol."},{"key":"10.1016\/j.plaphy.2026.111663_bib34","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1093\/treephys\/tpac149","article-title":"Physiological and transcriptome analyses of the effects of excessive water deficit on malic acid accumulation in apple","volume":"43","author":"Wang","year":"2022","journal-title":"Tree Physiol."},{"issue":"5","key":"10.1016\/j.plaphy.2026.111663_bib35","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.3390\/ijms20051171","article-title":"BplMYB46 from Betulaplatyphylla can form homodimers and heterodimers and is involved in salt and osmotic stresses","volume":"20","author":"Wang","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.plaphy.2026.111663_bib36","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1104\/pp.20.00476","article-title":"The apple microR171i-SCARECROW-LIKE PROTEINS 26.1 module enhances drought stress tolerance by integrating ascorbic acid metabolism","volume":"184","author":"Wang","year":"2020","journal-title":"Plant Physiol."},{"key":"10.1016\/j.plaphy.2026.111663_bib37","doi-asserted-by":"crossref","first-page":"1884","DOI":"10.1111\/j.1365-3040.2012.02523.x","article-title":"The bHLH transcription factor MdbHLH3 promotes anthocyan in accumulation and fruit colouration in response to low temperature in apples","volume":"35","author":"Xie","year":"2012","journal-title":"Plant Cell Environ."},{"key":"10.1016\/j.plaphy.2026.111663_bib38","first-page":"151","article-title":"Isolation of vacuoles from immature apple fruit flesh and compartmentation of sugars, organic acids, phenolic compounds and amino acids","volume":"25","author":"Yamaki","year":"1984","journal-title":"Plant Cell Physiol."},{"key":"10.1016\/j.plaphy.2026.111663_bib39","first-page":"305","article-title":"Responses of fruit growth, quality, and productivity to crop load in apple cv. Ultra Red Gala\/MM111","volume":"127","author":"Yuri","year":"2011","journal-title":"SciHorti"},{"key":"10.1016\/j.plaphy.2026.111663_bib40","doi-asserted-by":"crossref","first-page":"2059","DOI":"10.1093\/plphys\/kiac023","article-title":"MdWRKY126 modulates malate accumulation in apple fruit by regulating cytosolic malate dehydrogenase (MdMDH5)","volume":"188","author":"Zhang","year":"2022","journal-title":"Plant Physiol."},{"key":"10.1016\/j.plaphy.2026.111663_bib41","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1104\/pp.20.00208","article-title":"BTB-TAZ domain protein MdBT2 modulates malate accumulation and vacuolar acidification in response to nitrate","volume":"183","author":"Zhang","year":"2020","journal-title":"Plant Physiol."},{"key":"10.1016\/j.plaphy.2026.111663_bib42","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1016\/j.foodchem.2010.05.053","article-title":"Developmental changes of carbohydrates, organic acids, amino acids, and phenolic compounds in \u2018Honeycrisp\u2019 apple flesh","volume":"123","author":"Zhang","year":"2010","journal-title":"Food Chem."},{"key":"10.1016\/j.plaphy.2026.111663_bib43","doi-asserted-by":"crossref","first-page":"1877","DOI":"10.1093\/plphys\/kiad111","article-title":"Allelic variation of MdMYB123 controls malic acid content by regulating MdMa1 and MdMa11 expression in apple","volume":"192","author":"Zheng","year":"2023","journal-title":"Plant Physiol."},{"key":"10.1016\/j.plaphy.2026.111663_bib44","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1016\/S2095-3119(16)61571-X","article-title":"Peach yield and fruit quality is maintained under miId deficit irrigation in semi-arid China","volume":"5","author":"Zhou","year":"2017","journal-title":"J. Integr. Agric."}],"container-title":["Plant Physiology and Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0981942826006492?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0981942826006492?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T19:47:20Z","timestamp":1790624840000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0981942826006492"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":44,"alternative-id":["S0981942826006492"],"URL":"https:\/\/doi.org\/10.1016\/j.plaphy.2026.111663","relation":{},"ISSN":["0981-9428"],"issn-type":[{"value":"0981-9428","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"MdMYB70 transcription factor modulates malate accumulation under drought stress in apple","name":"articletitle","label":"Article Title"},{"value":"Plant Physiology and Biochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.plaphy.2026.111663","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Published by Elsevier Masson SAS.","name":"copyright","label":"Copyright"}],"article-number":"111663"}}