{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T03:53:33Z","timestamp":1791345213410,"version":"4.3.1"},"reference-count":194,"publisher":"Elsevier BV","issue":"3-4","license":[{"start":{"date-parts":[[2005,9,1]],"date-time":"2005-09-01T00:00:00Z","timestamp":1125532800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prostaglandins, Leukotrienes and Essential Fatty Acids"],"published-print":{"date-parts":[[2005,9]]},"DOI":"10.1016\/j.plefa.2005.05.002","type":"journal-article","created":{"date-parts":[[2005,7,7]],"date-time":"2005-07-07T14:56:08Z","timestamp":1120748168000},"page":"141-162","source":"Crossref","is-referenced-by-count":368,"title":["Lipoxins and aspirin-triggered 15-epi-lipoxins are the first lipid mediators of endogenous anti-inflammation and resolution"],"prefix":"10.1016","volume":"73","author":[{"given":"Charles N.","family":"Serhan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.plefa.2005.05.002_bib1","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1038\/scientificamerican0502-46","article-title":"Atherosclerosis: the new view","volume":"286","author":"Libby","year":"2002","journal-title":"Sci. Am."},{"key":"10.1016\/j.plefa.2005.05.002_bib2","doi-asserted-by":"crossref","first-page":"5335","DOI":"10.1073\/pnas.81.17.5335","article-title":"Lipoxins: novel series of biologically active compounds formed from arachidonic acid in human leukocytes","volume":"81","author":"Serhan","year":"1984","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.plefa.2005.05.002_bib3","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1172\/JCI114503","article-title":"Lipoxin formation during human neutrophil\u2013platelet interactions. Evidence for the transformation of leukotriene A4 by platelet 12-lipoxygenase in vitro","volume":"85","author":"Serhan","year":"1990","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.plefa.2005.05.002_bib4","doi-asserted-by":"crossref","first-page":"8720","DOI":"10.1016\/S0021-9258(18)31505-9","article-title":"Synthesis of lipoxins and other lipoxygenase products by macrophages from the rainbow trout, Oncorhynchus mykiss","volume":"266","author":"Pettitt","year":"1991","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.plefa.2005.05.002_bib5","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1021\/bi00170a002","article-title":"Lipoxin biosynthesis by trout macrophages involves the formation of epoxide intermediates","volume":"33","author":"Rowley","year":"1994","journal-title":"Biochemistry"},{"key":"10.1016\/j.plefa.2005.05.002_bib6","doi-asserted-by":"crossref","first-page":"9475","DOI":"10.1073\/pnas.92.21.9475","article-title":"Aspirin triggers previously undescribed bioactive eicosanoids by human endothelial cell\u2013leukocyte interactions","volume":"92","author":"Cl\u00e0ria","year":"1995","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.plefa.2005.05.002_bib7","doi-asserted-by":"crossref","first-page":"14609","DOI":"10.1021\/bi00044a041","article-title":"Design of lipoxin A4 stable analogs that block transmigration and adhesion of human neutrophils","volume":"34","author":"Serhan","year":"1995","journal-title":"Biochemistry"},{"key":"10.1016\/j.plefa.2005.05.002_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0005-2760(94)90185-6","article-title":"Lipoxin biosynthesis and its impact in inflammatory and vascular events","volume":"1212","author":"Serhan","year":"1994","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.plefa.2005.05.002_bib9","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/S0090-6980(97)00001-4","article-title":"Lipoxins and novel aspirin-triggered 15-epi-lipoxins (ATL): a jungle of cell\u2013cell interactions or a therapeutic opportunity?","volume":"53","author":"Serhan","year":"1997","journal-title":"Prostaglandins"},{"key":"10.1016\/j.plefa.2005.05.002_bib10","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1126\/science.2820055","article-title":"Leukotrienes and lipoxins: structures, biosynthesis, and biological effects","volume":"237","author":"Samuelsson","year":"1987","journal-title":"Science"},{"key":"10.1016\/j.plefa.2005.05.002_bib11","series-title":"Les Prix Nobel: Nobel Prizes, Presentations, Biographies and Lectures","first-page":"129","article-title":"The prostaglandins: from the laboratory to the clinic","author":"Bergstr\u00f6m","year":"1982"},{"key":"10.1016\/j.plefa.2005.05.002_bib12","series-title":"Les Prix Nobel: Nobel Prizes, Presentations, Biographies and Lectures","first-page":"153","article-title":"From studies of biochemical mechanisms to novel biological mediators: prostaglandin endoperoxides, thromboxanes and leukotrienes","author":"Samuelsson","year":"1982"},{"key":"10.1016\/j.plefa.2005.05.002_bib13","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1016\/0006-291X(84)91486-4","article-title":"Trihydroxytetraenes: a novel series of compounds formed from arachidonic acid in human leukocytes","volume":"118","author":"Serhan","year":"1984","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.plefa.2005.05.002_bib14","doi-asserted-by":"crossref","first-page":"1572","DOI":"10.1172\/JCI116738","article-title":"Human alveolar macrophages have 15-lipoxygenase and generate 15(S)-hydroxy-5,8,11-cis-13-trans-eicosatetraenoic acid and lipoxins","volume":"92","author":"Levy","year":"1993","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.plefa.2005.05.002_bib15","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/0005-2760(89)90264-6","article-title":"On the relationship between leukotriene and lipoxin production by human neutrophils: evidence for differential metabolism of 15-HETE and 5-HETE","volume":"1004","author":"Serhan","year":"1989","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.plefa.2005.05.002_bib16","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1084\/jem.179.4.1225","article-title":"Granulocyte\/macrophage colony-stimulating factor stimulates the expression of the 5-lipoxygenase-activating protein (FLAP) in human neutrophils","volume":"179","author":"Pouliot","year":"1994","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.plefa.2005.05.002_bib17","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1172\/JCI118545","article-title":"Lymphocytes stimulate expression of 5-lipoxygenase and its activating protein in monocytes in vitro via granulocyte-macrophage colony stimulating factor and interleukin-3","volume":"97","author":"Ring","year":"1996","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.plefa.2005.05.002_bib18","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1182\/blood.V85.2.522.522","article-title":"Diverging signal transduction pathways activated by interleukin-8 and related chemokines in human neutrophils: interleukin-8, but not NAP-2 or GROA\u03b1, stimulates phospholipase D activity","volume":"85","author":"L\u2019Heureux","year":"1995","journal-title":"Blood"},{"key":"10.1016\/j.plefa.2005.05.002_bib19","doi-asserted-by":"crossref","first-page":"8340","DOI":"10.1073\/pnas.85.21.8340","article-title":"Lipoxins A4 and B4: comparison of icosanoids having bronchoconstrictor and vasodilator actions but lacking platelet aggregatory activity","volume":"85","author":"Lefer","year":"1988","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.plefa.2005.05.002_bib20","series-title":"Lipoxygenases and Their Products","first-page":"235","article-title":"Lipoxins: bioactive lipoxygenase interaction products","author":"Dahl\u00e9n","year":"1991"},{"key":"10.1016\/j.plefa.2005.05.002_bib21","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.1016\/S0006-291X(05)81354-3","article-title":"Inhibition of leukotriene B4-induced neutrophil migration by lipoxin A4: structure\u2013function relationships","volume":"180","author":"Lee","year":"1991","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.plefa.2005.05.002_bib22","doi-asserted-by":"crossref","first-page":"3438","DOI":"10.1073\/pnas.86.9.3438","article-title":"Lipoxin A4 antagonizes cellular and in vivo actions of leukotriene D4 in rat glomerular mesangial cells: evidence for competition at a common receptor","volume":"86","author":"Badr","year":"1989","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.plefa.2005.05.002_bib23","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1111\/j.1748-1716.1989.tb08805.x","article-title":"Lipoxin A4 inhibits leukotriene B4-induced inflammation in the hamster cheek pouch","volume":"137","author":"Hedqvist","year":"1989","journal-title":"Acta Physiol. Scand."},{"key":"10.1016\/j.plefa.2005.05.002_bib24","doi-asserted-by":"crossref","first-page":"8247","DOI":"10.1073\/pnas.96.14.8247","article-title":"Local and systemic delivery of a stable aspirin-triggered lipoxin prevents neutrophil recruitment in vivo","volume":"96","author":"Clish","year":"1999","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.plefa.2005.05.002_bib25","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1007\/BF03401642","article-title":"Aspirin-triggered lipoxins (15-epi-LX) are generated by the human lung adenocarcinoma cell line (A549)-neutrophil interactions and are potent inhibitors of cell proliferation","volume":"2","author":"Cl\u00e0ria","year":"1996","journal-title":"Mol. Med."},{"key":"10.1016\/j.plefa.2005.05.002_bib26","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1042\/cs0770195","article-title":"Lipoxin A4 and lipoxin B4 inhibit chemotactic responses of human neutrophils stimulated by leukotriene B4 and N-formyl-l-methionyl-l-leucyl-l-phenylalanine","volume":"77","author":"Lee","year":"1989","journal-title":"Clin. Sci."},{"key":"10.1016\/j.plefa.2005.05.002_bib27","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1084\/jem.172.5.1451","article-title":"Formation of lipoxins and leukotrienes during receptor-mediated interactions of human platelets and recombinant human granulocyte\/macrophage colony-stimulating factor-primed neutrophils","volume":"172","author":"Fiore","year":"1990","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.plefa.2005.05.002_bib28","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1006\/bbrc.1995.1183","article-title":"5,15-diHETE and lipoxins generated by neutrophils from endogenous arachidonic acid as asthma biomarkers","volume":"207","author":"Chavis","year":"1995","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.plefa.2005.05.002_bib29","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1084\/jem.183.4.1633","article-title":"5(S),15(S)-dihydroxyeicosatetraenoic acid and lipoxin generation in human polymorphonuclear cells: dual specificity of 5-lipoxygenase towards endogenous and exogenous precursors","volume":"183","author":"Chavis","year":"1996","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.plefa.2005.05.002_bib30","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/BF01782022","article-title":"Conversion of endogenous arachidonic acid to 5,15-diHETE and lipoxins by polymorphonuclear cells from patients with rheumatoid arthritis","volume":"44","author":"Thomas","year":"1995","journal-title":"Inflamm. Res."},{"key":"10.1016\/j.plefa.2005.05.002_bib31","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1111\/j.1398-9995.2004.00617.x","article-title":"Lipoxins in asthma: potential therapeutic mediators on bronchial inflammation?","volume":"59","author":"Bonnans","year":"2004","journal-title":"Allergy"},{"key":"10.1016\/j.plefa.2005.05.002_bib32","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1016\/j.jaci.2004.06.012","article-title":"Lipoxins in asthma","volume":"114","author":"Celik","year":"2004","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.plefa.2005.05.002_bib33","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1124\/jpet.103.063651","article-title":"Cooperation between aspirin-triggered lipoxin and nitric oxide (NO) mediates anti-adhesive properties of NCX-4016 (NO-aspirin) on neutrophil\u2013endothelial cell adherence","volume":"309","author":"Fiorucci","year":"2004","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.plefa.2005.05.002_bib34","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1177\/154411130301400102","article-title":"Lipoxins in chronic inflammation","volume":"14","author":"Kantarci","year":"2003","journal-title":"Crit. Rev. Oral Biol. Med."},{"key":"10.1016\/j.plefa.2005.05.002_bib35","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1038\/ni1056","article-title":"Defective lipoxin-mediated anti-inflammatory activity in the cystic fibrosis airway","volume":"5","author":"Karp","year":"2004","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.plefa.2005.05.002_bib36","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1097\/01.LAB.0000028823.53486.4A","article-title":"Urinary excretion of lipoxin A4 and related compounds: development of new extraction techniques for lipoxins","volume":"82","author":"Romano","year":"2002","journal-title":"Lab Invest."},{"key":"10.1016\/j.plefa.2005.05.002_bib37","doi-asserted-by":"crossref","first-page":"4345","DOI":"10.4049\/jimmunol.174.7.4345","article-title":"Molecular circuits of resolution: formation and actions of resolvins and protectins","volume":"174","author":"Bannenberg","year":"2005","journal-title":"J. Immunol."},{"key":"10.1016\/j.plefa.2005.05.002_bib38","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1161\/01.CIR.86.1.56","article-title":"Angioplasty triggers intracoronary leukotrienes and lipoxin A4. Impact of aspirin therapy","volume":"86","author":"Brezinski","year":"1992","journal-title":"Circulation"},{"key":"10.1016\/j.plefa.2005.05.002_bib39","doi-asserted-by":"crossref","first-page":"2201","DOI":"10.1172\/JCI119029","article-title":"Macrophage-mediated 15-lipoxygenase expression protects against atherosclerosis development","volume":"98","author":"Shen","year":"1996","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.plefa.2005.05.002_bib40","doi-asserted-by":"crossref","first-page":"6856","DOI":"10.4049\/jimmunol.171.12.6856","article-title":"Reduced inflammation and tissue damage in transgenic rabbits overexpressing 15-lipoxygenase and endogenous anti-inflammatory lipid mediators","volume":"171","author":"Serhan","year":"2003","journal-title":"J. Immunol."},{"key":"10.1016\/j.plefa.2005.05.002_bib41","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1016\/S0006-291X(88)80320-6","article-title":"Transcellular conversion of endogenous arachidonic acid to lipoxins in mixed human platelet\u2013granulocyte suspensions [published erratum appears in Biochem Biophys Res Commun 1989 Feb 28;159(1):370]","volume":"157","author":"Edenius","year":"1988","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.plefa.2005.05.002_bib42","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/0165-6147(93)90092-X","article-title":"Transcellular biosynthesis of leukotrienes and lipoxins via leukotriene A4 transfer","volume":"14","author":"Lindgren","year":"1993","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.plefa.2005.05.002_bib43","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/0006-291X(89)90017-X","article-title":"Phospholipid bilayers enhance the stability of leukotriene A4 and epoxytetraenes: stabilization of eicosanoids by liposomes","volume":"159","author":"Fiore","year":"1989","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.plefa.2005.05.002_bib44","doi-asserted-by":"crossref","first-page":"5173","DOI":"10.1016\/S0040-4039(00)85161-8","article-title":"A stereoselective and practical synthesis of 5,6(S,S)-epoxy-15(S)-hydroxy-7(E),9(E),11(Z),13(E)-eicosatetraenoic acid (4), possible precursor of the lipoxins","volume":"27","author":"Corey","year":"1986","journal-title":"Tetrahedron Lett."},{"key":"10.1016\/j.plefa.2005.05.002_bib45","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/0167-4889(92)90073-K","article-title":"Lipoxin generation by human megakaryocyte-induced 12-lipoxygenase","volume":"1133","author":"Sheppard","year":"1992","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.plefa.2005.05.002_bib46","doi-asserted-by":"crossref","first-page":"8269","DOI":"10.1021\/bi00150a021","article-title":"Lipoxin generation by permeabilized human platelets","volume":"31","author":"Romano","year":"1992","journal-title":"Biochemistry"},{"key":"10.1016\/j.plefa.2005.05.002_bib47","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1042\/bj2960127","article-title":"Lipoxin synthase activity of human platelet 12-lipoxygenase","volume":"296","author":"Romano","year":"1993","journal-title":"Biochem. J."},{"key":"10.1016\/j.plefa.2005.05.002_bib48","first-page":"380","article-title":"P-selectin mediates the interaction of circulating leukocytes with platelets and microvascular endothelium in response to oxidized lipoprotein in vivo","volume":"71","author":"Lehr","year":"1994","journal-title":"Lab Invest."},{"key":"10.1016\/j.plefa.2005.05.002_bib49","doi-asserted-by":"crossref","first-page":"7688","DOI":"10.1073\/pnas.91.16.7688","article-title":"Vitamin C prevents cigarette smoke-induced leukocyte aggregation and adhesion to endothelium in vivo","volume":"91","author":"Lehr","year":"1994","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.plefa.2005.05.002_bib50","first-page":"309","article-title":"Human 15-lipoxygenase: a potential effector molecule for interleukin-4","volume":"22","author":"Sigal","year":"1994","journal-title":"Adv. Prostaglandin Thromboxane Leukot. Res."},{"key":"10.1016\/j.plefa.2005.05.002_bib51","doi-asserted-by":"crossref","first-page":"27631","DOI":"10.1016\/S0021-9258(18)47031-7","article-title":"Induction of 15-lipoxygenase by interleukin-13 in human blood monocytes","volume":"269","author":"Nassar","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.plefa.2005.05.002_bib52","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/0006-291X(82)91575-3","article-title":"Formation of leukotrienes and other hydroxy acids during platelet\u2013neutrophil interactions in vitro","volume":"109","author":"Marcus","year":"1982","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.plefa.2005.05.002_bib53","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1016\/S0006-291X(05)81548-7","article-title":"Adhesion promotes transcellular leukotriene biosynthesis during neutrophil-glomerular endothelial cell interactions: inhibition by antibodies against CD18 and l-selectin","volume":"186","author":"Brady","year":"1992","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.plefa.2005.05.002_bib54","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/0165-6147(94)90027-2","article-title":"TH2 and \u2018TH2-like\u2019 cells in allergy and asthma: pharmacological perspectives","volume":"15","author":"Anderson","year":"1994","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.plefa.2005.05.002_bib55","doi-asserted-by":"crossref","first-page":"6266","DOI":"10.4049\/jimmunol.170.12.6266","article-title":"Aspirin-triggered lipoxin A4 and B4 analogs block extracellular signal-regulated kinase-dependent TNF-\u03b1 secretion from human T cells","volume":"170","author":"Ariel","year":"2003","journal-title":"J. Immunol."},{"key":"10.1016\/j.plefa.2005.05.002_bib56","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1096\/fj.04-2565com","article-title":"A synthetic eicosanoid LX-mimetic unravels host\u2013donor interactions in allogeneic BMT-induced GvHD to reveal an early protective role for host neutrophils","volume":"19","author":"Devchand","year":"2005","journal-title":"FASEB J."},{"key":"10.1016\/j.plefa.2005.05.002_bib57","doi-asserted-by":"crossref","first-page":"2267","DOI":"10.4049\/jimmunol.164.5.2267","article-title":"Cutting edge: lipoxin (LX) A4 and aspirin-triggered 15-epi-LXA4 block allergen-induced eosinophil trafficking","volume":"164","author":"Bandeira-Melo","year":"2000","journal-title":"J. Immunol."},{"key":"10.1016\/j.plefa.2005.05.002_bib58","doi-asserted-by":"crossref","first-page":"1937","DOI":"10.1096\/fj.02-0224fje","article-title":"Aspirin (ASA) regulates 5-lipoxygenase activity and peroxisome proliferator-activated receptor \u03b1-mediated CINC-1 release in rat liver cells: novel actions of lipoxin A4 (LXA4) and ASA-triggered 15-epi-LXA4","volume":"16","author":"Planagum\u00e0","year":"2002","journal-title":"FASEB J."},{"key":"10.1016\/j.plefa.2005.05.002_bib59","doi-asserted-by":"crossref","first-page":"6248","DOI":"10.1073\/pnas.87.16.6248","article-title":"Selective incorporation of (15S)-hydroxyeicosatetraenoic acid in phosphatidylinositol of human neutrophils: agonist-induced deacylation and transformation of stored hydroxyeicosanoids","volume":"87","author":"Brezinski","year":"1990","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.plefa.2005.05.002_bib60","doi-asserted-by":"crossref","first-page":"6377","DOI":"10.1073\/pnas.96.11.6377","article-title":"Salicylates and sulfasalazine, but not glucocorticoids, inhibit leukocyte accumulation by an adenosine-dependent mechanism that is independent of inhibition of prostaglandin synthesis and p105 of NF\u03baB","volume":"96","author":"Cronstein","year":"1999","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.plefa.2005.05.002_bib61","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1056\/NEJM199704033361401","article-title":"Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men","volume":"336","author":"Ridker","year":"1997","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.plefa.2005.05.002_bib62","doi-asserted-by":"crossref","first-page":"15178","DOI":"10.1073\/pnas.0405445101","article-title":"Aspirin triggers anti-inflammatory 15-epi-lipoxin A4 and inhibits thromboxane in a randomized human trial","volume":"101","author":"Chiang","year":"2004","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.plefa.2005.05.002_bib63","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1056\/NEJMoa050613","article-title":"A randomized trial of low-dose aspirin in the primary prevention of cardiovascular disease in women","volume":"352","author":"Ridker","year":"2005","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.plefa.2005.05.002_bib64","series-title":"Les Prix Nobel: Nobel Prizes, Presentations, Biographies and Lectures","first-page":"181","article-title":"Adventures and excursions in bioassay: the stepping stones to prostacyclin","author":"Vane","year":"1982"},{"key":"10.1016\/j.plefa.2005.05.002_bib65","doi-asserted-by":"crossref","first-page":"1860","DOI":"10.1172\/JCI1339","article-title":"Pathogen-induced chemokine secretion from model intestinal epithelium is inhibited by lipoxin A4 analogs","volume":"101","author":"Gewirtz","year":"1998","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.plefa.2005.05.002_bib66","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/S0165-6147(03)00166-4","article-title":"A magic bullet for mucosal protection and aspirin is the trigger!","volume":"24","author":"Wallace","year":"2003","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.plefa.2005.05.002_bib67","doi-asserted-by":"crossref","first-page":"3902","DOI":"10.1073\/pnas.052533799","article-title":"Lipid mediator-induced expression of bactericidal\/permeability-increasing protein (BPI) in human mucosal epithelia","volume":"99","author":"Canny","year":"2002","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.plefa.2005.05.002_bib68","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1124\/mol.51.1.52","article-title":"Altered sensitivity of aspirin-acetylated prostaglandin G\/H synthase-2 inhibition by nonsteroidal anti-inflammatory drugs","volume":"51","author":"Mancini","year":"1997","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.plefa.2005.05.002_bib69","doi-asserted-by":"crossref","first-page":"6586","DOI":"10.1074\/jbc.275.9.6586","article-title":"Spatial requirements for 15-(R)-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid synthesis within the cyclooxygenase active site of murine COX-2","volume":"275","author":"Rowlinson","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.plefa.2005.05.002_bib70","doi-asserted-by":"crossref","first-page":"1933","DOI":"10.1126\/science.289.5486.1933","article-title":"The productive conformation of arachidonic acid bound to prostaglandin synthase","volume":"289","author":"Malkowski","year":"2000","journal-title":"Science"},{"key":"10.1016\/j.plefa.2005.05.002_bib71","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1038\/384644a0","article-title":"Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents","volume":"384","author":"Kurumbail","year":"1996","journal-title":"Nature"},{"key":"10.1016\/j.plefa.2005.05.002_bib72","doi-asserted-by":"crossref","first-page":"4478","DOI":"10.1073\/pnas.071052598","article-title":"Biomechanical activation of vascular endothelium as a determinant of its functional phenotype","volume":"98","author":"Garcia-Cardena","year":"2001","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.plefa.2005.05.002_bib73","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1126\/science.280.5367.1268","article-title":"Aspirin-like molecules that covalently inactivate cyclooxygenase-2","volume":"280","author":"Kalgutkar","year":"1998","journal-title":"Science"},{"key":"10.1016\/j.plefa.2005.05.002_bib74","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1084\/jem.192.8.1197","article-title":"Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and transcellular processing","volume":"192","author":"Serhan","year":"2000","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.plefa.2005.05.002_bib75","first-page":"779","article-title":"Aspirin-triggered 15-epi-lipoxin A4 (ATL) generation by human leukocytes and murine peritonitis exudates: development of a specific 15-epi-LXA4 ELISA","volume":"287","author":"Chiang","year":"1998","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.plefa.2005.05.002_bib76","doi-asserted-by":"crossref","first-page":"9049","DOI":"10.1016\/S0021-9258(18)52976-8","article-title":"Molecular cloning of human prostaglandin endoperoxide synthase type II and demonstration of expression in response to cytokines","volume":"268","author":"Jones","year":"1993","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.plefa.2005.05.002_bib77","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1111\/j.1749-6632.2000.tb06318.x","article-title":"Endothelial dysfunction, hemodynamic forces, and atherogenesis","volume":"902","author":"Gimbrone","year":"2000","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.plefa.2005.05.002_bib78","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/S1471-4906(03)00079-6","article-title":"Proinflammatory cytokines and sepsis syndrome: not enough, or too much of a good thing?","volume":"24","author":"Netea","year":"2003","journal-title":"Trends Immunol."},{"key":"10.1016\/j.plefa.2005.05.002_bib79","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1038\/nri915","article-title":"Anti-inflammatory lipid mediators and insights into the resolution of inflammation","volume":"2","author":"Lawrence","year":"2002","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.plefa.2005.05.002_bib80","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/S0165-6147(00)01771-5","article-title":"Lipoxins: revelations on resolution","volume":"22","author":"McMahon","year":"2001","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.plefa.2005.05.002_bib81","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1677\/joe.0.1780029","article-title":"Glucocorticoid-mediated regulation of granulocyte apoptosis and macrophage phagocytosis of apoptotic cells: implications for the resolution of inflammation","volume":"178","author":"Heasman","year":"2003","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.plefa.2005.05.002_bib82","doi-asserted-by":"crossref","first-page":"177","DOI":"10.2174\/1568014023355881","article-title":"Endogenous chemical mediators in anti-inflammation and pro-resolution","volume":"1","author":"Serhan","year":"2002","journal-title":"Curr. Med. Chem.\u2014Anti-Inflammatory Anti-Allergy Agents"},{"key":"10.1016\/j.plefa.2005.05.002_bib83","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1038\/89759","article-title":"Lipid mediator class switching during acute inflammation: signals in resolution","volume":"2","author":"Levy","year":"2001","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.plefa.2005.05.002_bib84","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1084\/jem.20020760","article-title":"Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter pro-inflammation signals","volume":"196","author":"Serhan","year":"2002","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.plefa.2005.05.002_bib85","doi-asserted-by":"crossref","first-page":"14677","DOI":"10.1074\/jbc.M300218200","article-title":"Novel docosatrienes and 17S-resolvins generated from docosahexaenoic acid in murine brain, human blood and glial cells: autacoids in anti-inflammation","volume":"278","author":"Hong","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.plefa.2005.05.002_bib86","doi-asserted-by":"crossref","first-page":"43807","DOI":"10.1074\/jbc.M305841200","article-title":"Novel docosanoids inhibit brain ischemia-reperfusion-mediated leukocyte infiltration and pro-inflammatory gene expression","volume":"278","author":"Marcheselli","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.plefa.2005.05.002_bib87","series-title":"The Healing Hand: Man and Wound in the Ancient World","author":"Majno","year":"1975"},{"key":"10.1016\/j.plefa.2005.05.002_bib88","series-title":"Inflammation: Basic Principles and Clinical Correlates","first-page":"1360","year":"1999"},{"key":"10.1016\/j.plefa.2005.05.002_bib89","series-title":"Robbins Pathologic Basis of Disease","first-page":"1425","year":"1999"},{"key":"10.1016\/j.plefa.2005.05.002_bib90","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1038\/nature01320","article-title":"Points of control in inflammation","volume":"420","author":"Nathan","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.plefa.2005.05.002_bib91","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1177\/154405910308200202","article-title":"Resolution of inflammation: a new paradigm for the pathogenesis of periodontal diseases","volume":"82","author":"Van Dyke","year":"2003","journal-title":"J. Dent. Res."},{"key":"10.1016\/j.plefa.2005.05.002_bib92","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1038\/nrd1034","article-title":"The development of COX2 inhibitors","volume":"2","author":"Flower","year":"2003","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.plefa.2005.05.002_bib93","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1056\/NEJM199901213400306","article-title":"Treatment of asthma with drugs modifying the leukotriene pathway","volume":"340","author":"Drazen","year":"1999","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.plefa.2005.05.002_bib94","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.2165\/00003495-200059060-00001","article-title":"COX-2 selective nonsteoridal anti-inflammatory drugs: do they really offer any advantages?","volume":"59","author":"Jackson","year":"2000","journal-title":"Drugs"},{"key":"10.1016\/j.plefa.2005.05.002_bib95","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1001\/archinte.163.4.481","article-title":"Effect of selective cyclooxygenase 2 inhibitors and naproxen on short-tem risk of acute myocardial infarction in the elderly","volume":"163","author":"Mamdani","year":"2003","journal-title":"Arch. Intern. Med."},{"key":"10.1016\/j.plefa.2005.05.002_bib96","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1056\/NEJMoa050493","article-title":"Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial","volume":"352","author":"Bresalier","year":"2005","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.plefa.2005.05.002_bib97","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1056\/NEJMoa050330","article-title":"Complications of the COX-2 inhibitors parecoxib and valdecoxib after cardiac surgery","volume":"352","author":"Nussmeier","year":"2005","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.plefa.2005.05.002_bib98","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1056\/NEJMoa050405","article-title":"Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention","volume":"352","author":"Solomon","year":"2005","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.plefa.2005.05.002_bib99","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1080\/09629350290000041","article-title":"Cyclooxygenase-2 inhibitors: promise or peril?","volume":"11","author":"Mengle-Gaw","year":"2002","journal-title":"Mediators Inflamm."},{"key":"10.1016\/j.plefa.2005.05.002_bib100","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1038\/9550","article-title":"Inducible cycloxygenase may have anti-inflammatory properties","volume":"5","author":"Gilroy","year":"1999","journal-title":"Nat. Med."},{"key":"10.1016\/j.plefa.2005.05.002_bib101","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1006\/bbrc.2001.5841","article-title":"Identification of dual cyclooxygenase-eicosanoid oxidoreductase inhibitors: NSAIDs that inhibit PG-LX reductase\/LTB(4) dehydrogenase","volume":"288","author":"Clish","year":"2001","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.plefa.2005.05.002_bib102","doi-asserted-by":"crossref","first-page":"1663","DOI":"10.4049\/jimmunol.164.4.1663","article-title":"Cutting edge: lipoxins rapidly stimulate nonphlogistic phagocytosis of apoptotic neutrophils by monocyte-derived macrophages","volume":"164","author":"Godson","year":"2000","journal-title":"J. Immunol."},{"key":"10.1016\/j.plefa.2005.05.002_bib103","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1038\/nm748","article-title":"Multi-pronged inhibition of airway hyper-responsiveness and inflammation by lipoxin A4","volume":"8","author":"Levy","year":"2002","journal-title":"Nat. Med."},{"key":"10.1016\/j.plefa.2005.05.002_bib104","doi-asserted-by":"crossref","first-page":"25372","DOI":"10.1074\/jbc.M002863200","article-title":"Oxidoreductases in lipoxin A4 metabolic inactivation","volume":"275","author":"Clish","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.plefa.2005.05.002_bib105","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1042\/bst0310795","article-title":"Expression of BPI (bactericidal\/permeability-increasing protein) in human mucosal epithelia","volume":"31","author":"Levy","year":"2003","journal-title":"Biochem. Soc. Trans."},{"key":"10.1016\/j.plefa.2005.05.002_bib106","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0165-6147(93)90207-Z","article-title":"Structure-based drug design: applications in immunopharmacology and immunosuppression","volume":"14","author":"Navia","year":"1993","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.plefa.2005.05.002_bib107","series-title":"Inflammation: Basic Principles and Clinical Correlates","author":"Gallin","year":"1999"},{"key":"10.1016\/j.plefa.2005.05.002_bib108","doi-asserted-by":"crossref","first-page":"6313","DOI":"10.1021\/bi00076a002","article-title":"Lipoxin A4 metabolism by differentiated HL-60 cells and human monocytes: conversion to novel 15-oxo and dihydro products","volume":"32","author":"Serhan","year":"1993","journal-title":"Biochemistry"},{"key":"10.1016\/j.plefa.2005.05.002_bib109","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1084\/jem.183.1.137","article-title":"Lipoxin A4 and B4 are potent stimuli for human monocyte migration and adhesion: selective inactivation by dehydrogenation and reduction","volume":"183","author":"Maddox","year":"1996","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.plefa.2005.05.002_bib110","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/1050-1738(95)00055-E","article-title":"Potential vascular roles for lipoxins in the \u201cstop programs\u201d of host defense and inflammation","volume":"5","author":"Brady","year":"1995","journal-title":"Trends Cardiovasc. Med."},{"key":"10.1016\/j.plefa.2005.05.002_bib111","doi-asserted-by":"crossref","first-page":"1693","DOI":"10.1084\/jem.185.9.1693","article-title":"Aspirin-triggered 15-epi-lipoxin A4 and LXA4 stable analogs are potent inhibitors of acute inflammation: evidence for anti-inflammatory receptors","volume":"185","author":"Takano","year":"1997","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.plefa.2005.05.002_bib112","doi-asserted-by":"crossref","first-page":"5","DOI":"10.4049\/jimmunol.171.1.5","article-title":"Leukotrienes, sphingolipids, and leukocyte trafficking","volume":"171","author":"Yopp","year":"2003","journal-title":"J. Immunol."},{"key":"10.1016\/j.plefa.2005.05.002_bib113","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1038\/nm786","article-title":"Endogenous lipid- and peptide-derived anti-inflammatory pathways generated with glucocorticoid and aspirin treatment activate the lipoxin A(4) receptor","volume":"8","author":"Perretti","year":"2002","journal-title":"Nat. Med."},{"key":"10.1016\/j.plefa.2005.05.002_bib114","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1038\/nrd1383","article-title":"Inflammation resolution: new opportunities for drug discovery","volume":"3","author":"Gilroy","year":"2004","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.plefa.2005.05.002_bib115","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1172\/JCI13375","article-title":"Unorthodox routes to prostanoid formation: new twists in cyclooxygenase-initiated pathways","volume":"107","author":"Serhan","year":"2001","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.plefa.2005.05.002_bib116","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.prostaglandins.2004.03.005","article-title":"Resolvins, docosatrienes, and neuroprotectins, novel omega-3-derived mediators, and their aspirin-triggered endogenous epimers: an overview of their protective roles in catabasis","volume":"73","author":"Serhan","year":"2004","journal-title":"Prostaglandins Other Lipid Mediat."},{"key":"10.1016\/j.plefa.2005.05.002_bib117","doi-asserted-by":"crossref","first-page":"6972","DOI":"10.1074\/jbc.272.11.6972","article-title":"Lipoxin A4 stable analogs are potent mimetics that stimulate human monocytes and THP-1 cells via a G-protein linked lipoxin A4 receptor","volume":"272","author":"Maddox","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.plefa.2005.05.002_bib118","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/S1471-4892(03)00072-9","article-title":"Targeting inflammatory diseases via apoptotic mechanisms","volume":"3","author":"Murphy","year":"2003","journal-title":"Curr. Opin. Phamacol."},{"key":"10.1016\/j.plefa.2005.05.002_bib119","series-title":"Robbins Pathologic Basis of Disease","first-page":"1","article-title":"Cellular pathology I: cell injury and cell death","author":"Cotran","year":"1999"},{"key":"10.1016\/j.plefa.2005.05.002_bib120","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1096\/fasebj.12.6.487","article-title":"Lipoxin B4 regulates human monocyte\/neutrophil adherence and motility: design of stable lipoxin B4 analogs with increased biologic activity","volume":"12","author":"Maddox","year":"1998","journal-title":"FASEB J."},{"key":"10.1016\/j.plefa.2005.05.002_bib121","doi-asserted-by":"crossref","first-page":"3223","DOI":"10.1016\/S0960-894X(03)00667-X","article-title":"Synthesis of methyl (5S,6R,7E,9E,11Z,13E,15S)-16-(4-fluorophenoxy)-5,6,15-trihydroxy-7,9,11,13-hexadecatetraenoate, an analogue of 15R-lipoxin A4","volume":"13","author":"Phillips","year":"2003","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.plefa.2005.05.002_bib122","doi-asserted-by":"crossref","first-page":"8717","DOI":"10.1016\/j.tetlet.2004.09.129","article-title":"First total synthesis of 7(S),16(R),17(S)-Resolvin D2, a potent anti-inflammatory lipid mediator","volume":"45","author":"Rodriguez","year":"2004","journal-title":"Tetrahedron Lett."},{"key":"10.1016\/j.plefa.2005.05.002_bib123","doi-asserted-by":"crossref","first-page":"2157","DOI":"10.1021\/jm030569l","article-title":"Novel 3-oxa lipoxin A4 analogues with enhanced chemical and metabolic stability have anti-inflammatory activity in vivo","volume":"47","author":"Guilford","year":"2004","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.plefa.2005.05.002_bib124","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1002\/bms.1200200202","article-title":"Characterization of lipoxins by combined gas chromatography and electron-capture negative ion chemical ionization mass spectrometry: formation of lipoxin A4 by stimulated human whole blood","volume":"20","author":"Brezinski","year":"1991","journal-title":"Biol. Mass Spectrom."},{"key":"10.1016\/j.plefa.2005.05.002_bib125","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1007\/BF02537069","article-title":"Agonist-induced lipoxin A4 generation: detection by a novel lipoxin A4-ELISA","volume":"28","author":"Levy","year":"1993","journal-title":"Lipids"},{"key":"10.1016\/j.plefa.2005.05.002_bib126","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/0145-2126(94)90053-1","article-title":"Leukotrienes and lipoxins\u2014new potential performers in the regulation of human myelopoiesis","volume":"18","author":"Stenke","year":"1994","journal-title":"Leukemia Res."},{"key":"10.1016\/j.plefa.2005.05.002_bib127","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1084\/jem.180.1.253","article-title":"Identification of a human cDNA encoding a functional high affinity lipoxin A4 receptor","volume":"180","author":"Fiore","year":"1994","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.plefa.2005.05.002_bib128","doi-asserted-by":"crossref","first-page":"3395","DOI":"10.1182\/blood.V81.12.3395.3395","article-title":"Induction of functional lipoxin A4 receptors in HL-60 cells","volume":"81","author":"Fiore","year":"1993","journal-title":"Blood"},{"key":"10.1016\/j.plefa.2005.05.002_bib129","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1124\/pr.55.1.8","article-title":"International Union of Pharmacology XXXVII. Nomenclature for leukotriene and lipoxin receptors","volume":"55","author":"Brink","year":"2003","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.plefa.2005.05.002_bib130","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0002-9440(10)63937-5","article-title":"Selectivity of recombinant human leukotriene D4, leukotriene B4, and lipoxin A4 receptors with aspirin-triggered 15-epi-LXA4 and regulation of vascular and inflammatory responses","volume":"158","author":"Gronert","year":"2001","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.plefa.2005.05.002_bib131","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1016\/0006-291X(86)90380-3","article-title":"Activation of protein kinase C by lipoxin A and other eicosanoids. Intracellular action of oxygenation products of arachidonic acid","volume":"134","author":"Hansson","year":"1986","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.plefa.2005.05.002_bib132","doi-asserted-by":"crossref","first-page":"2736","DOI":"10.1096\/fj.01-0576fje","article-title":"Aspirin-triggered lipoxin A4 and lipoxin A4 up-regulate transcriptional corepressor NAB1 in human neutrophils","volume":"15","author":"Qiu","year":"2001","journal-title":"FASEB J."},{"key":"10.1016\/j.plefa.2005.05.002_bib133","doi-asserted-by":"crossref","first-page":"2091","DOI":"10.4049\/jimmunol.173.3.2091","article-title":"A stable aspirin-triggered lipoxin A4 analog blocks phosphorylation of leukocyte-specific protein 1 in human neutrophils","volume":"173","author":"Ohira","year":"2004","journal-title":"J. Immunol."},{"key":"10.1016\/j.plefa.2005.05.002_bib134","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.yexcr.2004.07.015","article-title":"Differential inside-out activation of beta2-integrins by leukotriene B4 and fMLP in human neutrophils","volume":"300","author":"Patcha","year":"2004","journal-title":"Exp. Cell. Res."},{"key":"10.1016\/j.plefa.2005.05.002_bib135","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1111\/j.1523-1755.2004.00487.x","article-title":"Lipoxins: potential anti-inflammatory, proresolution, and antifibrotic mediators in renal disease","volume":"65","author":"Kieran","year":"2004","journal-title":"Kidney Int."},{"key":"10.1016\/j.plefa.2005.05.002_bib136","first-page":"252","article-title":"Characterization of human neutrophil and endothelial cell ligand-operated extracellular acidification rate by microphysiometry: impact of reoxygenation","volume":"285","author":"Gronert","year":"1998","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.plefa.2005.05.002_bib137","doi-asserted-by":"crossref","first-page":"7594","DOI":"10.1021\/bi982861e","article-title":"Lipoxin A4: a new class of ligand for the Ah receptor","volume":"38","author":"Schaldach","year":"1999","journal-title":"Biochemistry"},{"key":"10.1016\/j.plefa.2005.05.002_bib138","doi-asserted-by":"crossref","first-page":"C888","DOI":"10.1152\/ajpcell.00507.2001","article-title":"Lateral membrane LXA4 receptors mediate LXA4's anti-inflammatory actions on intestinal epithelium","volume":"284","author":"Kucharzik","year":"2003","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.plefa.2005.05.002_bib139","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1038\/ni745","article-title":"Lipoxin-mediated inhibition of IL-12 production by DCs: a mechanism for regulation of microbial immunity","volume":"3","author":"Aliberti","year":"2002","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.plefa.2005.05.002_bib140","doi-asserted-by":"crossref","first-page":"5033","DOI":"10.4049\/jimmunol.174.8.5033","article-title":"Cyclooxygenase 2 plays a pivotal role in the resolution of acute lung injury","volume":"174","author":"Fukunaga","year":"2005","journal-title":"J. Immunol."},{"key":"10.1016\/j.plefa.2005.05.002_bib141","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1084\/jem.20031325","article-title":"Exogenous pathogen and plant 15-lipoxygenase initiate endogenous lipoxin A4 biosynthesis","volume":"199","author":"Bannenberg","year":"2004","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.plefa.2005.05.002_bib142","doi-asserted-by":"crossref","first-page":"2135","DOI":"10.1073\/pnas.0307308101","article-title":"The opportunistic pathogen Pseudomonas aeruginosa carries a novel secretable arachidonate 15-lipoxygenase","volume":"101","author":"Vance","year":"2004","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.plefa.2005.05.002_bib143","doi-asserted-by":"crossref","first-page":"3169","DOI":"10.4049\/jimmunol.174.6.3169","article-title":"Cutting edge: novel role of lipoxygenases in the inflammatory response: promotion of TNF mRNA decay by 15-hydroperoxyeicosatetraenoic acid in a monocytic cell line","volume":"174","author":"Ferrante","year":"2005","journal-title":"J. Immunol."},{"key":"10.1016\/j.plefa.2005.05.002_bib144","doi-asserted-by":"crossref","first-page":"F189","DOI":"10.1152\/ajprenal.00224.2003","article-title":"Lipoxins: endogenous regulators of inflammation","volume":"286","author":"McMahon","year":"2004","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"10.1016\/j.plefa.2005.05.002_bib145","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1172\/JCI1578","article-title":"Neutrophil-mediated changes in vascular permeability are inhibited by topical application of aspirin-triggered 15-epi-lipoxin A4 and novel lipoxin B4 stable analogues","volume":"101","author":"Takano","year":"1998","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.plefa.2005.05.002_bib146","doi-asserted-by":"crossref","first-page":"3727","DOI":"10.4049\/jimmunol.174.6.3727","article-title":"Modulation of phagocytosis of apoptotic neutrophils by supernatant from dexamethasone-treated macrophages and annexin-derived peptide Ac(2\u201326)","volume":"174","author":"Maderna","year":"2005","journal-title":"J. Immunol."},{"key":"10.1016\/j.plefa.2005.05.002_bib147","doi-asserted-by":"crossref","first-page":"C988","DOI":"10.1152\/ajpcell.1999.276.4.C988","article-title":"LXA4, aspirin-triggered 15-epi-LXA4, and their analogs selectively downregulate PMN azurophilic degranulation","volume":"276","author":"Gewirtz","year":"1999","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.plefa.2005.05.002_bib148","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1016\/S0002-9440(10)63181-1","article-title":"Lipoxins inhibit Akt\/PKB activation and cell cycle progression in human mesangial cells","volume":"164","author":"Mitchell","year":"2004","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.plefa.2005.05.002_bib149","doi-asserted-by":"crossref","first-page":"15736","DOI":"10.1073\/pnas.0404722101","article-title":"A beta-oxidation-resistant lipoxin A4 analog treats hapten-induced colitis by attenuating inflammation and immune dysfunction","volume":"101","author":"Fiorucci","year":"2004","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.plefa.2005.05.002_bib150","doi-asserted-by":"crossref","first-page":"G76","DOI":"10.1152\/ajpgi.00295.2003","article-title":"Aspirin, but not NO-releasing aspirin (NCX-4016), interacts with selective COX-2 inhibitors to aggravate gastric damage and inflammation","volume":"286","author":"Wallace","year":"2004","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.plefa.2005.05.002_bib151","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1038\/sj.bjp.0705912","article-title":"Lipoxins and novel 15-epi-lipoxin analogs display potent anti-inflammatory actions after oral administration","volume":"143","author":"Bannenberg","year":"2004","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.plefa.2005.05.002_bib152","series-title":"Cells, Tissues, and Disease: Principles of General Pathology","author":"Majno","year":"2004"},{"key":"10.1016\/j.plefa.2005.05.002_bib153","doi-asserted-by":"crossref","first-page":"15267","DOI":"10.1074\/jbc.M410638200","article-title":"A role for the mouse 12\/15-lipoxygenase pathway in promoting epithelial wound healing and host defense","volume":"280","author":"Gronert","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.plefa.2005.05.002_bib154","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1096\/fj.02-0770com","article-title":"Human ALX receptor regulates neutrophil recruitment in transgenic mice: roles in inflammation and host-defense","volume":"17","author":"Devchand","year":"2003","journal-title":"FASEB J."},{"key":"10.1016\/j.plefa.2005.05.002_bib155","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1172\/JCI116601","article-title":"Lipoxin A4 modulates transmigration of human neutrophils across intestinal epithelial monolayers","volume":"92","author":"Colgan","year":"1993","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.plefa.2005.05.002_bib156","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.4049\/jimmunol.164.2.1029","article-title":"Cyclooxygenase-2-derived prostaglandin E2 and lipoxin A4 accelerate resolution of allergic edema in Angiostrongylus costaricensis-infected rats: relationship with concurrent eosinophilia","volume":"164","author":"Bandeira-Melo","year":"2000","journal-title":"J. Immunol."},{"key":"10.1016\/j.plefa.2005.05.002_bib157","doi-asserted-by":"crossref","first-page":"4761","DOI":"10.1021\/bi992551b","article-title":"Lipoxin A4 analogues inhibit leukocyte recruitment to Porphyromonas gingivalis: a role for cyclooxygenase-2 and lipoxins in periodontal disease","volume":"39","author":"Pouliot","year":"2000","journal-title":"Biochemistry"},{"key":"10.1016\/j.plefa.2005.05.002_bib158","doi-asserted-by":"crossref","first-page":"3650","DOI":"10.4049\/jimmunol.166.6.3650","article-title":"Nociceptin stimulates neutrophil chemotaxis and recruitment: inhibition by aspirin-triggered-15-epi-lipoxin A4","volume":"166","author":"Serhan","year":"2001","journal-title":"J. Immunol."},{"key":"10.1016\/j.plefa.2005.05.002_bib159","doi-asserted-by":"crossref","first-page":"2264","DOI":"10.4049\/jimmunol.156.6.2264","article-title":"Lipoxin A4 and B4 inhibit leukotriene-stimulated interactions of human neutrophils and endothelial cells","volume":"156","author":"Papayianni","year":"1996","journal-title":"J. Immunol."},{"key":"10.1016\/j.plefa.2005.05.002_bib160","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1096\/fasebj.13.8.903","article-title":"Polyisoprenyl phosphate (PIPP) signaling regulates phospholipase D activity: a \u201cstop\u201d signaling switch for aspirin-triggered lipoxin A4","volume":"13","author":"Levy","year":"1999","journal-title":"FASEB J."},{"key":"10.1016\/j.plefa.2005.05.002_bib161","doi-asserted-by":"crossref","first-page":"16678","DOI":"10.1021\/bi00051a016","article-title":"Lipoxin A4 receptor activation is distinct from that of the formyl peptide receptor in myeloid cells: inhibition of CD11\/18 expression by lipoxin A4-lipoxin A4 receptor interaction","volume":"34","author":"Fiore","year":"1995","journal-title":"Biochemistry"},{"key":"10.1016\/j.plefa.2005.05.002_bib162","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1016\/0006-291X(90)90625-W","article-title":"Lipoxin A4 inhibits phosphoinositide hydrolysis in human neutrophils","volume":"167","author":"Grandordy","year":"1990","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.plefa.2005.05.002_bib163","doi-asserted-by":"crossref","first-page":"4132","DOI":"10.1182\/blood.V94.12.4132","article-title":"Anti-inflammatory actions of lipoxin A4 stable analogs are demonstrable in human whole blood: modulation of leukocyte adhesion molecules and inhibition of neutrophil\u2013endothelial interactions","volume":"94","author":"Filep","year":"1999","journal-title":"Blood"},{"key":"10.1016\/j.plefa.2005.05.002_bib164","doi-asserted-by":"crossref","first-page":"266","DOI":"10.4049\/jimmunol.138.1.266","article-title":"Lipoxin A-induced inhibition of human natural killer cell cytotoxicity: studies on stereospecificity of inhibition and mode of action","volume":"138","author":"Ramstedt","year":"1987","journal-title":"J. Immunol."},{"key":"10.1016\/j.plefa.2005.05.002_bib165","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1084\/jem.187.8.1285","article-title":"Identification of a human enterocyte lipoxin A4 receptor that is regulated by IL-13 and IFN-\u03b3and inhibits TNF-\u03b1-induced IL-8 release","volume":"187","author":"Gronert","year":"1998","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.plefa.2005.05.002_bib166","doi-asserted-by":"crossref","first-page":"2660","DOI":"10.4049\/jimmunol.164.5.2660","article-title":"Lipoxin A4 inhibits IL-1 beta-induced IL-6, IL-8, and matrix metalloproteinase-3 production in human synovial fibroblasts and enhances synthesis of tissue inhibitors of metalloproteinases","volume":"164","author":"Sodin-Semrl","year":"2000","journal-title":"J. Immunol."},{"key":"10.1016\/j.plefa.2005.05.002_bib167","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/0014-5793(90)80718-X","article-title":"Protein kinase C-regulated production of prostacyclin by rat endothelium is increased in the presence of lipoxin A4","volume":"263","author":"Leszczynski","year":"1990","journal-title":"FEBS Lett."},{"key":"10.1016\/j.plefa.2005.05.002_bib168","doi-asserted-by":"crossref","first-page":"9967","DOI":"10.1073\/pnas.94.18.9967","article-title":"Lipoxin A4 stable analogs inhibit leukocyte rolling and adherence in the rat mesenteric microvasculature: role of P-selectin","volume":"94","author":"Scalia","year":"1997","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.plefa.2005.05.002_bib169","doi-asserted-by":"crossref","first-page":"27566","DOI":"10.1074\/jbc.M001015200","article-title":"Lipoxin A4 antagonizes the mitogenic effects of leukotriene D4 in human renal mesangial cells: differential activation of MAP kinases through distinct receptors","volume":"275","author":"McMahon","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.plefa.2005.05.002_bib170","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1164\/ajrccm\/145.6.1281","article-title":"The effects of lipoxin A4 on airway responses in asthmatic subjects","volume":"145","author":"Christie","year":"1992","journal-title":"Am. Rev. Respir. Dis."},{"key":"10.1016\/j.plefa.2005.05.002_bib171","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1084\/jem.191.7.1197","article-title":"Activation of lipoxin A4 receptors by aspirin-triggered lipoxins and select peptides evokes ligand-specific responses in inflammation","volume":"191","author":"Chiang","year":"2000","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.plefa.2005.05.002_bib172","doi-asserted-by":"crossref","first-page":"13551","DOI":"10.1021\/bi001196i","article-title":"Mutations of serine 235\u2013237 and tyrosine 302 residues in the human lipoxin A4 receptor intracellular domains result in sustained signaling","volume":"39","author":"Kang","year":"2000","journal-title":"Biochemistry"},{"key":"10.1016\/j.plefa.2005.05.002_bib173","first-page":"380","article-title":"Lipoxins: novel anti-inflammatory therapeutics?","volume":"1","author":"Godson","year":"2000","journal-title":"Curr. Opin. Invest. Drugs"},{"key":"10.1016\/j.plefa.2005.05.002_bib174","doi-asserted-by":"crossref","first-page":"7063","DOI":"10.4049\/jimmunol.169.12.7063","article-title":"An aspirin-triggered lipoxin A4 stable analog displays a unique topical anti-inflammatory profile","volume":"169","author":"Schottelius","year":"2002","journal-title":"J. Immunol."},{"key":"10.1016\/j.plefa.2005.05.002_bib175","doi-asserted-by":"crossref","first-page":"10937","DOI":"10.1073\/pnas.1933204100","article-title":"Interaction of a selective cyclooxygenase-2 inhibitor with aspirin and NO-releasing aspirin in the human gastric mucosa","volume":"100","author":"Fiorucci","year":"2003","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.plefa.2005.05.002_bib176","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1172\/JCI7016","article-title":"Leukotriene B4 receptor transgenic mice reveal novel protective roles for lipoxins and aspirin-triggered lipoxins in reperfusion","volume":"104","author":"Chiang","year":"1999","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.plefa.2005.05.002_bib177","doi-asserted-by":"crossref","first-page":"2497","DOI":"10.1097\/01.ASN.0000032417.73640.72","article-title":"Lipoxins, aspirin-triggered epi-lipoxins, lipoxin stable analogues, and the resolution of inflammation: stimulation of macrophage phagocytosis of apoptotic neutrophils in vivo","volume":"13","author":"Mitchell","year":"2002","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.plefa.2005.05.002_bib178","doi-asserted-by":"crossref","first-page":"1923","DOI":"10.1084\/jem.189.12.1923","article-title":"Lipoxin (LX)A4 and aspirin-triggered 15-epi-LXA4 inhibit tumor necrosis factor 1\u03b1-initiated neutrophil responses and trafficking: regulators of a cytokine-chemokine axis","volume":"189","author":"Hachicha","year":"1999","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.plefa.2005.05.002_bib179","doi-asserted-by":"crossref","first-page":"13266","DOI":"10.1073\/pnas.202296999","article-title":"Lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 inhibit peroxynitrite formation, NF-kappa B and AP-1 activation, and IL-8 gene expression in human leukocytes","volume":"99","author":"Jozsef","year":"2002","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.plefa.2005.05.002_bib180","first-page":"A949","article-title":"A novel inhibitor of angiogenesis: aspirin-triggered 15R lipoxin A4","volume":"15","author":"Fierro","year":"2001","journal-title":"FASEB J."},{"key":"10.1016\/j.plefa.2005.05.002_bib181","first-page":"177","article-title":"Lipoxins and aspirin-triggered 15-epi-lipoxins are endogenous components of antiinflammation: emergence of the counterregulatory side","volume":"49","author":"Serhan","year":"2001","journal-title":"Arch. Immunol. Ther. Exp."},{"key":"10.1016\/j.plefa.2005.05.002_bib182","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1164\/ajrccm\/141.6.1453","article-title":"Identification of lipoxin A4 and its relationship to the sulfidopeptide leukotrienes C4, D4, and E4 in the bronchoalveolar lavage fluids obtained from patients with selected pulmonary diseases","volume":"141","author":"Lee","year":"1990","journal-title":"Am. Rev. Respir. Dis."},{"key":"10.1016\/j.plefa.2005.05.002_bib183","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/S0006-291X(05)81285-9","article-title":"Formation and proliferative effects of lipoxins in human bone marrow","volume":"180","author":"Stenke","year":"1991","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.plefa.2005.05.002_bib184","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1164\/rccm.200201-053OC","article-title":"Lipoxins are potential endogenous antiinflammatory mediators in asthma","volume":"165","author":"Bonnans","year":"2002","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.plefa.2005.05.002_bib185","first-page":"18","article-title":"Differential expression of lipoxin and lipoxin receptors in osteoarthritis cartilage: a functional genomic analysis","author":"Dave","year":"2003","journal-title":"J. Leukocyte Biol. Suppl."},{"key":"10.1016\/j.plefa.2005.05.002_bib186","doi-asserted-by":"crossref","first-page":"2989","DOI":"10.1182\/blood.V78.11.2989.2989","article-title":"Deficient lipoxin synthesis: a novel platelet dysfunction in myeloproliferative disorders with special reference to blastic crisis of chronic myelogenous leukemia","volume":"78","author":"Stenke","year":"1991","journal-title":"Blood"},{"key":"10.1016\/j.plefa.2005.05.002_bib187","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1038\/sj.bjp.0705356","article-title":"Evidence that 5-lipoxygenase and acetylated cyclooxygenase 2-derived eicosanoids regulate leukocyte-endothelial adherence in response to aspirin","volume":"139","author":"Fiorucci","year":"2003","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.plefa.2005.05.002_bib188","doi-asserted-by":"crossref","first-page":"5260","DOI":"10.4049\/jimmunol.168.10.5260","article-title":"Lipoxin A4 analogs attenuate induction of intestinal epithelial proinflammatory gene expression and reduce the severity of dextran sodium sulfate-induced colitis","volume":"168","author":"Gewirtz","year":"2002","journal-title":"J. Immunol."},{"key":"10.1016\/j.plefa.2005.05.002_bib189","doi-asserted-by":"crossref","first-page":"13375","DOI":"10.1073\/pnas.96.23.13375","article-title":"Transfection of rat kidney with human 15-lipoxygenase suppresses inflammation and preserves function in experimental glomerulonephritis","volume":"96","author":"Munger","year":"1999","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.plefa.2005.05.002_bib190","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1097\/01.ASN.0000015795.74094.91","article-title":"15-epi-16-(para-fluorophenoxy)-lipoxin A4-methyl ester, a synthetic analogue of 15-epi-lipoxin A4, is protective in experimental ischemic acute renal failure","volume":"13","author":"Leonard","year":"2002","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.plefa.2005.05.002_bib191","doi-asserted-by":"crossref","first-page":"1817","DOI":"10.1096\/fj.02-0416fje","article-title":"Lipoxin, leukotriene, and PDGF receptors cross-talk to regulate mesangial cell proliferation","volume":"16","author":"McMahon","year":"2002","journal-title":"FASEB J."},{"key":"10.1016\/j.plefa.2005.05.002_bib192","doi-asserted-by":"crossref","first-page":"7671","DOI":"10.1073\/pnas.0409271102","article-title":"Resolvin E1, a novel endogenous lipid mediator derived from omega-3 eicosapentaenoic acid, protects against TNBS-induced colitis","volume":"102","author":"Arita","year":"2005","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.plefa.2005.05.002_bib193","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1124\/jpet.300.2.385","article-title":"Novel lipid mediator regulators of endothelial cell proliferation and migration: aspirin-triggered-15R-lipoxin A4 and lipoxin A4","volume":"300","author":"Fierro","year":"2002","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.plefa.2005.05.002_bib194","unstructured":"P.R. Cotran, C. Hsu, C.N. Serhan. 1995. Lipoxin derivatives reduce intraocular pressure in rabbits (abstract). Association for Research in Vision and Ophthalmology Conference, 1995."}],"container-title":["Prostaglandins, Leukotrienes and Essential Fatty Acids"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0952327805000803?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0952327805000803?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,1,27]],"date-time":"2024-01-27T19:47:34Z","timestamp":1706384854000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0952327805000803"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,9]]},"references-count":194,"journal-issue":{"issue":"3-4","published-print":{"date-parts":[[2005,9]]}},"alternative-id":["S0952327805000803"],"URL":"https:\/\/doi.org\/10.1016\/j.plefa.2005.05.002","relation":{},"ISSN":["0952-3278"],"issn-type":[{"value":"0952-3278","type":"print"}],"subject":[],"published":{"date-parts":[[2005,9]]}}}