{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T23:30:01Z","timestamp":1792279801326,"version":"4.4.0"},"reference-count":184,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001411","name":"Indian Council of Medical Research","doi-asserted-by":"publisher","award":["5\/7\/1069\/13-RCH"],"award-info":[{"award-number":["5\/7\/1069\/13-RCH"]}],"id":[{"id":"10.13039\/501100001411","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","plefa.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Prostaglandins, Leukotrienes and Essential Fatty Acids"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1016\/j.plefa.2020.102203","type":"journal-article","created":{"date-parts":[[2020,11,12]],"date-time":"2020-11-12T11:58:13Z","timestamp":1605182293000},"page":"102203","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":37,"special_numbering":"C","title":["Exploring the role of LC-PUFA metabolism in pregnancy complications"],"prefix":"10.1016","volume":"163","author":[{"given":"Aditi A.","family":"Godhamgaonkar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nisha S.","family":"Wadhwani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sadhana R.","family":"Joshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.plefa.2020.102203_bib0001","doi-asserted-by":"crossref","first-page":"S4","DOI":"10.1186\/1471-2458-11-S3-S4","article-title":"The effect of folic acid, protein energy and multiple micronutrient supplements in pregnancy on stillbirths","volume":"11","author":"Imdad","year":"2011","journal-title":"BMC Public Health"},{"key":"10.1016\/j.plefa.2020.102203_bib0002","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1159\/000348459","article-title":"One-carbon metabolism, fetal growth and long-term consequences","volume":"74","author":"Kalhan","year":"2013","journal-title":"Nestle Nutr. Inst. Workshop Ser."},{"key":"10.1016\/j.plefa.2020.102203_bib0003","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1007\/s00394-014-0654-7","article-title":"Maternal diet, bioactive molecules, and exercising as reprogramming tools of metabolic programming","volume":"53","author":"Mathias","year":"2014","journal-title":"Eur. J. Nutr."},{"key":"10.1016\/j.plefa.2020.102203_bib0004","doi-asserted-by":"crossref","first-page":"439","DOI":"10.21608\/jhiph.2011.20174","article-title":"Relationship between nutritional pattern and occurrence of pre-eclampsia and eclampsia among primigravidae","volume":"41","author":"Abdel-Fattah","year":"2011","journal-title":"J. High Inst. Public Heal."},{"key":"10.1016\/j.plefa.2020.102203_bib0005","doi-asserted-by":"crossref","first-page":"3517","DOI":"10.1210\/jc.2007-0718","article-title":"Maternal vitamin D deficiency increases the risk of preeclampsia","volume":"92","author":"Bodnar","year":"2007","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.plefa.2020.102203_bib0006","doi-asserted-by":"crossref","first-page":"9492","DOI":"10.3390\/nu7115467","article-title":"Impact of maternal diet on the epigenome during in utero life and the developmental programming of diseases in childhood and adulthood","volume":"7","author":"Lee","year":"2015","journal-title":"Nutrients"},{"key":"10.1016\/j.plefa.2020.102203_bib0007","doi-asserted-by":"crossref","first-page":"506","DOI":"10.5468\/ogs.2017.60.6.506","article-title":"What is fetal programming?: A lifetime health is under the control of in utero health","volume":"60","author":"Kwon","year":"2017","journal-title":"Obstet. Gynecol. Sci."},{"key":"10.1016\/j.plefa.2020.102203_bib0008","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1093\/jn\/137.4.855","article-title":"Dietary (n-3) fatty acids and brain development","volume":"137","author":"Innis","year":"2007","journal-title":"J. Nutr."},{"key":"10.1016\/j.plefa.2020.102203_bib0009","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.earlhumdev.2006.11.003","article-title":"Visual acuity and cognitive outcomes at 4 years of age in a double-blind, randomized trial of long-chain polyunsaturated fatty acid-supplemented infant formula","volume":"83","author":"Birch","year":"2007","journal-title":"Early Hum. Dev."},{"key":"10.1016\/j.plefa.2020.102203_bib0010","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1515\/jpm.2010.112","article-title":"Long chain polyunsaturated fatty acids in mothers of preterm babies","volume":"38","author":"Kilari","year":"2010","journal-title":"J. Perinat. Med."},{"key":"10.1016\/j.plefa.2020.102203_bib0011","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.plefa.2016.08.010","article-title":"The effect of n-3 LCPUFA supplementation on oxidative stress and inflammation in the placenta and maternal plasma during pregnancy","volume":"113","author":"Leghi","year":"2016","journal-title":"Prostaglandins Leukot. Essent. Fat. Acids"},{"key":"10.1016\/j.plefa.2020.102203_bib0012","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1002\/fsn3.121","article-title":"Long-chain polyunsaturated fatty acid sources and evaluation of their nutritional and functional properties","volume":"2","author":"Abedi","year":"2014","journal-title":"Food Sci. Nutr."},{"key":"10.1016\/j.plefa.2020.102203_bib0013","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.plefa.2012.10.001","article-title":"Effects of fatty acids on angiogenic activity in the placental extravillious trophoblast cells","volume":"88","author":"Basak","year":"2013","journal-title":"Prostaglandins. Leukot. Essent. Fatty Acids"},{"key":"10.1016\/j.plefa.2020.102203_bib0014","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1016\/j.placenta.2011.06.009","article-title":"Docosahexaenoic acid stimulates tube formation in first trimester trophoblast cells, HTR8\/SVneo","volume":"32","author":"Johnsen","year":"2011","journal-title":"Placenta"},{"key":"10.1016\/j.plefa.2020.102203_bib0015","doi-asserted-by":"crossref","first-page":"1505S","DOI":"10.1093\/ajcn\/83.6.1505S","article-title":"n-3 polyunsaturated fatty acids, inflammation, and inflammatory diseases","volume":"83","author":"Calder","year":"2006","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.plefa.2020.102203_bib0016","doi-asserted-by":"crossref","first-page":"611","DOI":"10.3109\/09637486.2015.1077790","article-title":"A review of recent evidence in human studies of n-3 and n-6 PUFA intake on cardiovascular disease, cancer, and depressive disorders: Does the ratio really matter?","volume":"66","author":"Marventano","year":"2015","journal-title":"Int. J. Food Sci. Nutr."},{"key":"10.1016\/j.plefa.2020.102203_bib0017","doi-asserted-by":"crossref","unstructured":"W.R.Schgfer, K.Werner, Arachidonate decidua metabolites metabolism as main in human placenta, profiles fetal membranes, and myometrium\u00a0: lipoxygenase in HPLC and cytochrome products, (1996) 231\u2013238.","DOI":"10.1016\/S0143-4004(96)90043-0"},{"key":"10.1016\/j.plefa.2020.102203_bib0018","doi-asserted-by":"crossref","first-page":"4743","DOI":"10.1167\/iovs.08-2462","article-title":"Novel anti inflammatory and pro resolving lipid mediators block inflammatory angiogenesis","volume":"50","author":"Jin","year":"2009","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.plefa.2020.102203_bib0019","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.plefa.2017.09.017","article-title":"The role of specialized pro-resolving mediators in maternal-fetal health","volume":"126","author":"Elliott","year":"2017","journal-title":"Prostaglandins. Leukot. Essent. Fatty Acids"},{"key":"10.1016\/j.plefa.2020.102203_bib0020","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1007\/s00011-020-01358-6","article-title":"Changes of lipoxin levels during pregnancy and the monthly-cycle, condition the normal course of pregnancy or pathology","volume":"69","author":"Szczuko","year":"2020","journal-title":"Inflamm. Res."},{"key":"10.1016\/j.plefa.2020.102203_bib0021","doi-asserted-by":"crossref","DOI":"10.3390\/ijms20184402","article-title":"Omega-3 fatty acid-derived resolvin D2 regulates human placental vascular smooth muscle and extravillous trophoblast activities","volume":"20","author":"Ulu","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.plefa.2020.102203_bib0022","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1038\/nature13479","article-title":"Novel pro-resolving lipid mediators in inflammation are leads for resolution physiology","volume":"510","author":"Serhan","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.plefa.2020.102203_bib0023","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1016\/j.bbalip.2010.08.002","article-title":"Specialized pro-resolving lipid mediators in the inflammatory response: An update","volume":"1801","author":"Bannenberg","year":"2010","journal-title":"Biochim. Biophys. Acta."},{"key":"10.1016\/j.plefa.2020.102203_bib0024","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1038\/mi.2015.99","article-title":"Human milk proresolving mediators stimulate resolution of acute inflammation","volume":"9","author":"Arnardottir","year":"2016","journal-title":"Mucosal. Immunol."},{"key":"10.1016\/j.plefa.2020.102203_bib0025","first-page":"11","article-title":"Omega-3 fatty acid supplementation, pro-resolving mediators, and clinical outcomes in maternal-infant pairs","author":"Nordgren","year":"2019","journal-title":"Nutrients"},{"key":"10.1016\/j.plefa.2020.102203_bib0026","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1530\/REP-14-0549","article-title":"Effects of maternal n-3 fatty acid supplementation on placental cytokines, pro-resolving lipid mediators and their precursors","volume":"149","author":"Keelan","year":"2015","journal-title":"Reproduction"},{"key":"10.1016\/j.plefa.2020.102203_bib0027","article-title":"Regulation of arachidonic acid oxidation and metabolism by lipid electrophiles","author":"Trostchansky","year":"2020","journal-title":"Prostaglandins Other Lipid Mediat."},{"key":"10.1016\/j.plefa.2020.102203_bib0028","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1189\/jlb.0811402","article-title":"Lipid-cytokine-chemokine cascades orchestrate leukocyte recruitment in inflammation","volume":"91","author":"Sadik","year":"2012","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.plefa.2020.102203_bib0029","first-page":"302","article-title":"Reno-protective mechanisms of epoxyeicosatrienoic acids in cardiovascular disease","author":"Elmarakby","year":"2012","journal-title":"Am. J. Physiol. - Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.plefa.2020.102203_bib0030","unstructured":"Wood;, A. Trostchansky, H.Rubbo, ur l P re, Biochimie. (2020) 106408. 10.1016\/j.prostaglandins.2020.106408."},{"key":"10.1016\/j.plefa.2020.102203_bib0031","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1038\/ncprheum0616","article-title":"New endogenous anti-inflammatory and proresolving lipid mediators: implications for rheumatic diseases","volume":"3","author":"Yacoubian","year":"2007","journal-title":"Nat. Clin. Pract. Rheumatol."},{"key":"10.1016\/j.plefa.2020.102203_bib0032","doi-asserted-by":"crossref","DOI":"10.2174\/1570159X18666200807144530","article-title":"The emerging role for the double-edged impact of arachidonic acidderived eicosanoids in the neuroinflammatory background of depression","author":"Regulska","year":"2020","journal-title":"Curr. Neuropharmacol."},{"key":"10.1016\/j.plefa.2020.102203_bib0033","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/aji.13206","article-title":"Pre-eclampsia is associated with reduced resolvin D1 and maresin 1 to leukotriene B4 ratios in the plasma","volume":"83","author":"Oliveira Perucci","year":"2020","journal-title":"Am. J. Reprod. Immunol."},{"key":"10.1016\/j.plefa.2020.102203_bib0034","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.tjog.2019.11.002","article-title":"Efficacy of n-3 fatty acids supplementation on the prevention of pregnancy induced-hypertension or preeclampsia: A systematic review and meta-analysis","volume":"59","author":"Bakouei","year":"2020","journal-title":"taiwan J. Obstet. Gynecol."},{"key":"10.1016\/j.plefa.2020.102203_bib0035","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1111\/j.1365-3016.2012.01281.x","article-title":"Effect of women's nutrition before and during early pregnancy on maternal and infant outcomes: A systematic review","volume":"26","author":"Ramakrishnan","year":"2012","journal-title":"Paediatr. Perinat. Epidemiol."},{"key":"10.1016\/j.plefa.2020.102203_bib0036","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1093\/humupd\/dmp025","article-title":"Role of micronutrients in the periconceptional period","volume":"16","author":"Cetin","year":"2009","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.plefa.2020.102203_bib0037","doi-asserted-by":"crossref","first-page":"3441","DOI":"10.1113\/jphysiol.2009.173062","article-title":"Long chain fatty acids and dietary fats in fetal nutrition","volume":"587","author":"Cetin","year":"2009","journal-title":"J. Physiol."},{"key":"10.1016\/j.plefa.2020.102203_bib0038","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1002\/wdev.238","article-title":"Altered development and function of the placental regions in preeclampsia and its association with long-chain polyunsaturated fatty acids","volume":"5","author":"Rani","year":"2016","journal-title":"Wiley Interdiscip. Rev. Dev. Biol."},{"key":"10.1016\/j.plefa.2020.102203_bib0039","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1385\/ENDO:19:1:43","article-title":"Lipid metabolism in pregnancy and its consequences in the fetus and newborn","volume":"19","author":"Herrera","year":"2002","journal-title":"Endocrine"},{"key":"10.1016\/j.plefa.2020.102203_bib0040","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000365423","article-title":"Introduction to fatty acids and lipids","volume":"112","author":"Burdge","year":"2015","journal-title":"World Rev. Nutr. Diet."},{"key":"10.1016\/j.plefa.2020.102203_bib0041","doi-asserted-by":"crossref","first-page":"3831","DOI":"10.3390\/ijms16023831","article-title":"Fatty acid signaling: The new function of intracellular lipases","volume":"16","author":"Papackova","year":"2015","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.plefa.2020.102203_bib0042","doi-asserted-by":"crossref","first-page":"529","DOI":"10.3390\/nu3050529","article-title":"Docosahexaenoic acid (DHA): An ancient nutrient for the modern human brain","volume":"3","year":"2011","journal-title":"Nutrients"},{"key":"10.1016\/j.plefa.2020.102203_bib0043","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.mehy.2017.01.009","article-title":"Altered metabolic homeostasis between vitamin D and long chain polyunsaturated fatty acids in preeclampsia","volume":"100","author":"Nandi","year":"2017","journal-title":"Med. Hypotheses"},{"key":"10.1016\/j.plefa.2020.102203_bib0044","first-page":"248","volume":"19","author":"Flowers","year":"2014","journal-title":"Metabolism"},{"key":"10.1016\/j.plefa.2020.102203_bib0045","doi-asserted-by":"crossref","first-page":"16","DOI":"10.3945\/ajcn.117.153825","article-title":"\u03c9-3 and \u03c9-6 long-chain PUFAs and their enzymatic metabolites in neovascular eye diseases","volume":"106","author":"Gong","year":"2017","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.plefa.2020.102203_bib0046","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.tips.2014.03.001","article-title":"COX-2-derived endocannabinoid metabolites as novel inflammatory mediators","volume":"35","author":"Alhouayek","year":"2014","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.plefa.2020.102203_bib0047","doi-asserted-by":"crossref","DOI":"10.1016\/j.plefa.2020.102080","article-title":"Maternal dietary fatty acids and their roles in human placental development","volume":"155","author":"Duttaroy","year":"2020","journal-title":"Prostaglandins Leukot. Essent. Fat. Acids"},{"key":"10.1016\/j.plefa.2020.102203_bib0048","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1159\/000193000","article-title":"An assessment of dietary docosahexaenoic acid requirements for brain accretion and turnover during early childhood","volume":"99","author":"Hadley","year":"2009","journal-title":"World Rev. Nutr. Diet."},{"key":"10.1016\/j.plefa.2020.102203_bib0049","doi-asserted-by":"crossref","DOI":"10.1155\/2012\/539426","article-title":"Health implications of high dietary omega-6 polyunsaturated Fatty acids","volume":"2012","author":"Patterson","year":"2012","journal-title":"J. Nutr. Metab."},{"key":"10.1016\/j.plefa.2020.102203_bib0050","doi-asserted-by":"crossref","unstructured":"D.W.Nebert, K.Wikvall, W.L.Miller, D.W.Nebert, Human cytochromes P450 in health and disease, (2013).","DOI":"10.1098\/rstb.2012.0431"},{"key":"10.1016\/j.plefa.2020.102203_bib0051","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1016\/S0021-9258(18)81182-6","article-title":"The stoichiometry of C21 hydroxylation of steroids by adrenocortical microsomes","volume":"238","author":"Cooper","year":"1963","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.plefa.2020.102203_bib0052","first-page":"1619","article-title":"Some aspects on the hydroxylation of drugs, steroid hormones and fatty acids (omega-oxidation) in rat liver microsomes","volume":"349","author":"Orrenius","year":"1968","journal-title":"Hoppe. Seylers. Z. Physiol. Chem."},{"key":"10.1016\/j.plefa.2020.102203_bib0053","doi-asserted-by":"crossref","unstructured":"A.A.S.Hee-Yong, Acid metabolism, 1851 (2016) 356\u2013365. 10.1016\/j.bbalip.2014.07.020.Cytochrome.","DOI":"10.1016\/j.bbalip.2014.07.020"},{"key":"10.1016\/j.plefa.2020.102203_bib0054","doi-asserted-by":"crossref","first-page":"2845","DOI":"10.1681\/ASN.2017030252","article-title":"Effect of cytochrome P450 metabolites of arachidonic acid in nephrology","volume":"28","author":"Fan","year":"2017","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.plefa.2020.102203_bib0055","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1016\/S1734-1140(10)70311-X","article-title":"Cytochrome p450-dependent metabolism of \u03c9-6 and \u03c9-3 long-chain polyunsaturated fatty acids","volume":"62","author":"Arnold","year":"2010","journal-title":"Pharmacol. Rep."},{"key":"10.1016\/j.plefa.2020.102203_bib0056","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1146\/annurev.nutr.012809.104742","article-title":"Fatty acid supply to the human fetus","volume":"30","author":"Haggarty","year":"2010","journal-title":"Annu. Rev. Nutr."},{"key":"10.1016\/j.plefa.2020.102203_bib0057","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.plefa.2014.05.006","article-title":"Altered maternal proportions of long chain polyunsaturated fatty acids and their transport leads to disturbed fetal stores in preeclampsia","volume":"91","author":"Wadhwani","year":"2014","journal-title":"Prostaglandins Leukot. Essent. Fat. Acids"},{"key":"10.1016\/j.plefa.2020.102203_bib0058","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1079\/PNS2001130","article-title":"Dietary essential fatty acids and brain function: a developmental perspective on mechanisms","volume":"61","author":"Wainwright","year":"2002","journal-title":"Proc. Nutr. Soc."},{"key":"10.1016\/j.plefa.2020.102203_bib0059","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1007\/s00418-003-0538-z","article-title":"Localization of brain-type fatty acid-binding protein in Kupffer cells of mice and its transient decrease in response to lipopolysaccharide","volume":"119","author":"Abdelwahab","year":"2003","journal-title":"Histochem. Cell Biol."},{"key":"10.1016\/j.plefa.2020.102203_bib0060","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fgene.2011.00057","article-title":"Mechanisms involved in the selective transfer of long chain polyunsaturated fatty acids to the fetus","volume":"2","author":"Gil-S\u00e1nchez","year":"2011","journal-title":"Front. Genet."},{"key":"10.1016\/j.plefa.2020.102203_bib0061","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1093\/advances\/nmy120","article-title":"The importance of maternal folate status for brain development and function of offspring","volume":"10","author":"Naninck","year":"2019","journal-title":"Adv. Nutr."},{"key":"10.1016\/j.plefa.2020.102203_bib0062","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1146\/annurev.cellbio.21.122303.120624","article-title":"Docosahexaenoic acid, fatty acid\u2013interacting proteins, and neuronal function: breastmilk and fish are good for you","volume":"21","author":"Marszalek","year":"2005","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"10.1016\/j.plefa.2020.102203_bib0063","first-page":"162","article-title":"Omega-3 Fatty Acid supplementation during pregnancy","volume":"1","author":"Greenberg","year":"2008","journal-title":"Rev. Obstet. Gynecol."},{"key":"10.1016\/j.plefa.2020.102203_bib0064","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.bbacli.2015.06.004","article-title":"Differential regional fatty acid distribution in normotensive and preeclampsia placenta","volume":"4","author":"Rani","year":"2015","journal-title":"BBA Clin."},{"key":"10.1016\/j.plefa.2020.102203_bib0065","doi-asserted-by":"crossref","first-page":"799","DOI":"10.3390\/nu4070799","article-title":"Benefits of docosahexaenoic acid, folic acid, vitamin D and iodine on foetal and infant brain development and function following maternal supplementation during pregnancy and lactation","volume":"4","author":"Morse","year":"2012","journal-title":"Nutrients"},{"key":"10.1016\/j.plefa.2020.102203_bib0066","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.placenta.2017.02.007","article-title":"Implantation and extravillous trophoblast invasion: From rare archival specimens to modern biobanking","volume":"56","author":"Moser","year":"2017","journal-title":"Placenta"},{"key":"10.1016\/j.plefa.2020.102203_bib0067","doi-asserted-by":"crossref","first-page":"2077","DOI":"10.1016\/j.ejca.2009.04.026","article-title":"The effect of omega-3 FAs on tumour angiogenesis and their therapeutic potential","volume":"45","author":"Spencer","year":"2009","journal-title":"Eur. J. Cancer"},{"key":"10.1016\/j.plefa.2020.102203_bib0068","first-page":"147","article-title":"Maternal dietary omega-3 fatty acids and placental function","author":"Jones","year":"2014","journal-title":"Reproduction"},{"key":"10.1016\/j.plefa.2020.102203_bib0069","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1095\/biolreprod.112.103754","article-title":"Maternal dietary omega-3 fatty acid supplementation reduces placental oxidative stress and increases fetal and placental growth in the Rat1","volume":"88","author":"Jones","year":"2013","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.plefa.2020.102203_bib0070","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.earlhumdev.2009.02.003","article-title":"Effect of docosahexaenoic acid on oxidative stress in placental trophoblast cells","volume":"85","author":"Shoji","year":"2009","journal-title":"Early Hum. Dev."},{"key":"10.1016\/j.plefa.2020.102203_bib0071","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1530\/REP-13-0239","article-title":"Differential effects of docosahexaenoic acid on preterm and term placental pro-oxidant\/antioxidant balance","volume":"146","author":"Stark","year":"2013","journal-title":"Reproduction"},{"key":"10.1016\/j.plefa.2020.102203_bib0072","first-page":"2690","article-title":"A diet supplemented with n-3 polyunsaturated fatty acids influences the metabomscic and endocrine response of rabbit does and their offspring","volume":"95","author":"Rodr\u00edguez","year":"2017","journal-title":"J. Anim. Sci."},{"key":"10.1016\/j.plefa.2020.102203_bib0073","first-page":"19","article-title":"Effects of arachidonic and docosohexahenoic acid supplementation during gestation in rats. Implication of placental oxidative stress","author":"Reyes-Hern\u00e1ndez","year":"2018","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.plefa.2020.102203_bib0074","doi-asserted-by":"crossref","unstructured":"Shresthaa, J.S.Cuffea, O.J.Hollanda, A. VPerkinsa, D.AndrewJMcAinchb, c Deanne H.Hryciwb, Linoleic acid increases prostaglandin E2 release and reduces mitochondrial respiration and cell viability in human, (2019) 94\u2013108. 10.33594\/000000007.","DOI":"10.33594\/000000007"},{"key":"10.1016\/j.plefa.2020.102203_bib0075","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0137309","article-title":"Dietary omega-3 fatty acid supplementation reduces inflammation in obese pregnant women: a randomized double-blind controlled clinical trial","volume":"10","author":"Haghiac","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.plefa.2020.102203_bib0076","doi-asserted-by":"crossref","DOI":"10.1016\/j.jri.2020.103177","article-title":"Inflammation with the participation of arachidonic (AA) and linoleic acid (LA) derivatives (HETEs and HODEs) is necessary in the course of a normal reproductive cycle and pregnancy","volume":"141","author":"Kikut","year":"2020","journal-title":"J. Reprod. Immunol."},{"key":"10.1016\/j.plefa.2020.102203_bib0077","doi-asserted-by":"crossref","DOI":"10.1016\/j.plefa.2019.102041","article-title":"Plasma oxylipins and unesterified precursor fatty acids are altered by DHA supplementation in pregnancy: Can they help predict risk of preterm birth?","volume":"153","author":"Ramsden","year":"2020","journal-title":"Prostaglandins Leukot. Essent. Fat. Acids"},{"key":"10.1016\/j.plefa.2020.102203_bib0078","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1095\/biolreprod.107.064717","article-title":"Effect of the interaction between lipoxygenase pathway and progesterone on the regulation of hydroxysteroid 11-beta dehydrogenase 2 in cultured human term placental trophoblasts1","volume":"78","author":"Sato","year":"2008","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.plefa.2020.102203_bib0079","doi-asserted-by":"crossref","first-page":"1889","DOI":"10.3892\/mmr.2014.2017","article-title":"Effect of 20-hydroxyeicosatetraenoic acid on biological behavior of human villous trophoblasts and uterine vascular smooth muscle cells","volume":"9","author":"Lu","year":"2014","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.plefa.2020.102203_bib0080","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.2741\/2151","article-title":"Role of the prostaglandins in labour and prostaglandin receptor inhibitors in the prevention of preterm labour","volume":"12","author":"Olson","year":"2007","journal-title":"Front. Biosci."},{"key":"10.1016\/j.plefa.2020.102203_bib0081","unstructured":"T.Sun, S.Li, H.Diao, C.Teng, H.Wang, Z.Yang, endometrium of the rhesus monkey during the menstrual cycle, (2004). 10.1530\/rep.1.00121."},{"key":"10.1016\/j.plefa.2020.102203_bib0082","first-page":"11570","article-title":"A novel pathway involving progesterone receptor, 12 \/ 15-lipoxygenase-derived eicosanoids, and peroxisome proliferator-activated receptor","volume":"279","author":"Li","year":"2004","journal-title":"Regulates Implantation in Mice *"},{"key":"10.1016\/j.plefa.2020.102203_bib0083","doi-asserted-by":"crossref","first-page":"372","DOI":"10.3389\/fphys.2014.00372","article-title":"Endothelial dysfunction and preeclampsia: role of oxidative stress","volume":"5","author":"S\u00e1nchez-Aranguren","year":"2014","journal-title":"Front. Physiol."},{"key":"10.1016\/j.plefa.2020.102203_bib0084","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.theriogenology.2019.09.046","article-title":"Prostaglandin F2\u03b1 stimulates angiogenesis at the embryo-maternal interface during early pregnancy in the pig","volume":"142","author":"Kaczynski","year":"2020","journal-title":"Theriogenology"},{"key":"10.1016\/j.plefa.2020.102203_bib0085","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1093\/ajh\/hps011","article-title":"Maternal and fetal epoxyeicosatrienoic acids in normotensive and preeclamptic pregnancies","volume":"26","author":"Jiang","year":"2013","journal-title":"Am. J. Hypertens."},{"key":"10.1016\/j.plefa.2020.102203_bib0086","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1159\/000365767","article-title":"Current information and asian perspectives on long-chain polyunsaturated fatty acids in pregnancy, lactation, and infancy: Systematic review and practice recommendations from an early nutrition academy workshop","volume":"65","author":"Koletzko","year":"2014","journal-title":"Ann. Nutr. Metab."},{"key":"10.1016\/j.plefa.2020.102203_bib0087","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0148752","article-title":"Polyunsaturated fatty acid (PUFA) status in pregnant women: associations with sleep quality, inflammation, and length of gestation","volume":"11","author":"Christian","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.plefa.2020.102203_bib0088","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1038\/s41372-019-0573-9","article-title":"Impact of erythrocyte long-chain omega-3 polyunsaturated fatty acid levels in early pregnancy on birth outcomes: findings from a Belgian cohort study","volume":"40","author":"Hoge","year":"2020","journal-title":"J. Perinatol."},{"key":"10.1016\/j.plefa.2020.102203_bib0089","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1017\/S0007114508006740","article-title":"Associations between neonatal birth dimensions and maternal essential and trans fatty acid contents during pregnancy and at delivery","volume":"101","author":"Dirix","year":"2009","journal-title":"Br. J. Nutr."},{"key":"10.1016\/j.plefa.2020.102203_bib0090","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1016\/j.clnu.2017.06.010","article-title":"Maternal plasma n-3 and n-6 polyunsaturated fatty acids during pregnancy and features of fetal health: Fetal growth velocity, birth weight and duration of pregnancy","volume":"37","author":"Grootendorst-van Mil","year":"2018","journal-title":"Clin. Nutr."},{"key":"10.1016\/j.plefa.2020.102203_bib0091","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1002\/ajhb.21129","article-title":"Associations of long-chain polyunsaturated fatty acid concentrations with birth outcome in term Indian mothers and their neonates","volume":"23","author":"Kilari","year":"2011","journal-title":"Am. J. Hum. Biol."},{"key":"10.1016\/j.plefa.2020.102203_bib0092","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0147359","article-title":"Maternal fatty acids and their association with birth outcome: A prospective study","volume":"11","author":"Meher","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.plefa.2020.102203_bib0093","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/s11745-015-4098-5","article-title":"Reduced maternal erythrocyte long chain polyunsaturated fatty acids exist in early pregnancy in preeclampsia","volume":"51","author":"Wadhwani","year":"2016","journal-title":"Lipids"},{"key":"10.1016\/j.plefa.2020.102203_bib0094","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.ebiom.2018.07.009","article-title":"Plasma concentrations of long chain N-3 fatty acids in early and mid-pregnancy and risk of early preterm birth","volume":"35","author":"Olsen","year":"2018","journal-title":"EBioMedicine"},{"key":"10.1016\/j.plefa.2020.102203_bib0095","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.plefa.2005.11.002","article-title":"n-6 and n-3 Long-chain polyunsaturated fatty acids in the erythrocyte membrane of Brazilian preterm and term neonates and their mothers at delivery","volume":"74","author":"Pontes","year":"2006","journal-title":"Prostaglandins Leukot. Essent. Fat. Acids"},{"key":"10.1016\/j.plefa.2020.102203_bib0096","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.plefa.2011.06.003","article-title":"Reduced levels of placental long chain polyunsaturated fatty acids in preterm deliveries","volume":"85","author":"Dhobale","year":"2011","journal-title":"Prostaglandins Leukot. Essent. Fat. Acids"},{"key":"10.1016\/j.plefa.2020.102203_bib0097","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.prostaglandins.2017.07.003","article-title":"Cord blood eicosanoid signatures and newborn gestational age","volume":"133","author":"Gouveia-Figueira","year":"2017","journal-title":"Prostaglandins Other Lipid Mediat."},{"key":"10.1016\/j.plefa.2020.102203_bib0098","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S0301-2115(00)00266-9","article-title":"Maternal thromboxane and prostacyclin levels in relation to fetal birth weight","volume":"93","author":"De Jong","year":"2000","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"key":"10.1016\/j.plefa.2020.102203_bib0099","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1002\/1520-6661(200007\/08)9:4<209::AID-MFM4>3.0.CO;2-S","article-title":"Umbilical cord serum levels of thromboxane B2 in term infants of women who participated in a placebo-controlled trial of low-dose aspirin","volume":"9","author":"Parker","year":"2000","journal-title":"J. Matern. Fetal. Med."},{"key":"10.1016\/j.plefa.2020.102203_bib0100","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/0002-9378(95)90285-6","article-title":"Maternal serum thromboxane B2 reduction versus pregnancy outcome in a low-dose aspirin trial","volume":"173","author":"Hauth","year":"1995","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.plefa.2020.102203_bib0101","article-title":"Periodontal disease, inflammatory cytokines, and PGE2 in pregnant patients at risk of preterm delivery: a pilot study","volume":"2018","author":"Uriza","year":"2018","journal-title":"Infect. Dis. Obstet. Gynecol."},{"key":"10.1016\/j.plefa.2020.102203_bib0102","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0038445","article-title":"Maternal diet modulates placenta growth and gene expression in a mouse model of diabetic pregnancy","volume":"7","author":"Kappen","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.plefa.2020.102203_bib0103","first-page":"1","article-title":"Impaired adenosine-mediated angiogenesis in preeclampsia: Potential implications for fetal programming","author":"Escudero","year":"2014","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.plefa.2020.102203_bib0104","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/j.placenta.2012.10.003","article-title":"The ever growing complexity of placental epigenetics - Role in adverse pregnancy outcomes and fetal programming","volume":"33","author":"Novakovic","year":"2012","journal-title":"Placenta"},{"key":"10.1016\/j.plefa.2020.102203_bib0105","doi-asserted-by":"crossref","first-page":"2256","DOI":"10.1210\/jc.2006-2403","article-title":"Dysregulation of placental endothelial lipase and lipoprotein lipase in intrauterine growth-restricted pregnancies","volume":"92","author":"Gauster","year":"2007","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.plefa.2020.102203_bib0106","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.plefa.2017.08.002","article-title":"Maternal long chain polyunsaturated fatty acid status and pregnancy complications","volume":"136","author":"Wadhwani","year":"2018","journal-title":"Prostaglandins Leukot. Essent. Fat. Acids"},{"key":"10.1016\/j.plefa.2020.102203_bib0107","first-page":"1","article-title":"A brief overview of preeclampsia","volume":"6","year":"2013","journal-title":"J. Clin. Med. Res."},{"key":"10.1016\/j.plefa.2020.102203_bib0108","unstructured":"M.J.Bell, NIH Public Access, (2011) 1\u201313. 10.1111\/j.1552-6909.2010.01172.x.A."},{"key":"10.1016\/j.plefa.2020.102203_bib0109","doi-asserted-by":"crossref","unstructured":"J.C.Pera\u00e7oli, R.De Carvalho, C.S\u00e9rgio, H.De Almeida, M.Costa, L.Gustavo, D.O.Francisco, L.Pereira, D.S.Henri, A.Korkes, I.Rodrigues, B.Maria, L.Costa, M.Dias, C.Junior, N.Sass, Pre-eclampsia \/ Eclampsia, (2019) 318\u2013332.","DOI":"10.1055\/s-0039-1687859"},{"key":"10.1016\/j.plefa.2020.102203_bib0110","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/j.tjog.2017.08.004","article-title":"Taiwanese Journal of Obstetrics & Gynecology Preeclampsia\u00a0: A review of the pathogenesis and possible management strategies based on its pathophysiological derangements","volume":"56","author":"El-sayed","year":"2017","journal-title":"taiwan J. Obstet. Gynecol."},{"key":"10.1016\/j.plefa.2020.102203_bib0111","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/j.placenta.2015.06.016","article-title":"Oxidative stress-induced C\/EBP\u03b2 inhibits \u03b2-catenin signaling molecule involving in the pathology of preeclampsia","volume":"36","author":"Zhuang","year":"2015","journal-title":"Placenta"},{"key":"10.1016\/j.plefa.2020.102203_bib0112","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1016\/j.placenta.2009.10.004","article-title":"Long-chain polyunsaturated fatty acids stimulate cellular fatty acid uptake in human placental choriocarcinoma (BeWo) cells","volume":"30","author":"Johnsen","year":"2009","journal-title":"Placenta"},{"key":"10.1016\/j.plefa.2020.102203_bib0113","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1093\/ajh\/hpw053","article-title":"Lipoxin A4 is increased in the plasma of preeclamptic women","volume":"29","author":"Perucci","year":"2016","journal-title":"Am. J. Hypertens."},{"key":"10.1016\/j.plefa.2020.102203_bib0114","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1111\/1440-1681.13095","article-title":"Metabolomics revealed decreased level of omega-3 PUFA-derived protective eicosanoids in pregnant women with pre-eclampsia","volume":"46","author":"Liu","year":"2019","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"key":"10.1016\/j.plefa.2020.102203_bib0115","doi-asserted-by":"crossref","unstructured":"K.D.Dangat, S.Mehendale, H.R.Yadav, S.Kilari, Long-chain polyunsaturated fatty acid composition of breast milk in pre-eclamptic mothers, (2010) 190\u2013194. 10.1159\/000252971.","DOI":"10.1159\/000252971"},{"key":"10.1016\/j.plefa.2020.102203_bib0116","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.plefa.2010.09.005","article-title":"Reduced placental docosahexaenoic acid levels associated with increased levels of sFlt-1 in preeclampsia","volume":"84","author":"Kulkarni","year":"2011","journal-title":"Prostaglandins Leukot. Essent. Fat. Acids"},{"key":"10.1016\/j.plefa.2020.102203_bib0117","doi-asserted-by":"crossref","first-page":"1973","DOI":"10.3109\/14767058.2014.974537","article-title":"Differential oxidative stress levels in mothers with preeclampsia delivering male and female babies","volume":"28","author":"Roy","year":"2015","journal-title":"J. Matern. Fetal. Neonatal Med."},{"key":"10.1016\/j.plefa.2020.102203_bib0118","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.ijgo.2007.08.011","article-title":"Fatty acids, antioxidants, and oxidative stress in pre-eclampsia","volume":"100","author":"Mehendale","year":"2008","journal-title":"Int. J. Gynecol. Obstet."},{"key":"10.1016\/j.plefa.2020.102203_bib0119","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/s00404-006-0140-4","article-title":"Erythrocyte omega-3 and omega-6 polyunsaturated fatty acids and preeclampsia risk in Peruvian women","volume":"274","author":"Qiu","year":"2006","journal-title":"Arch. Gynecol. Obstet."},{"key":"10.1016\/j.plefa.2020.102203_bib0120","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1097\/00001648-199505000-00007","article-title":"Omega-3 fatty acids in maternal erythrocytes and risk of preeclampsia","volume":"6","author":"Williams","year":"1995","journal-title":"Epidemiology"},{"key":"10.1016\/j.plefa.2020.102203_bib0121","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1016\/0002-9378(91)90521-R","article-title":"Decreased levels of polyunsaturated fatty acids in preeclampsia","volume":"164","author":"Wang","year":"1991","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.plefa.2020.102203_bib0122","doi-asserted-by":"crossref","unstructured":"K.H.Bakheit, K.Ghebremeskel, K.Pol, M.I.Elbashir, I.Adam, Erythrocyte omega-3 and omega-6 fatty acids profile in Sudanese women with pre-eclampsia, 30 (2010) 151\u2013154. 10.3109\/01443610903391005.","DOI":"10.3109\/01443610903391005"},{"key":"10.1016\/j.plefa.2020.102203_bib0123","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1016\/j.clinbiochem.2006.09.008","article-title":"Maternal erythrocyte omega-3 and omega-6 fatty acids, and plasma lipid concentrations, are associated with habitual dietary fish consumption in early pregnancy","volume":"39","author":"Williams","year":"2006","journal-title":"Clin. Biochem."},{"key":"10.1016\/j.plefa.2020.102203_bib0124","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1080\/10641950500281118","article-title":"Placental tissue levels of nonesterified polyunsaturated fatty acids in normal and preeclamptic pregnancies","volume":"24","author":"Wang","year":"2005","journal-title":"Hypertens. Pregnancy"},{"key":"10.1016\/j.plefa.2020.102203_bib0125","doi-asserted-by":"crossref","first-page":"449","DOI":"10.3109\/10641955.2014.931419","article-title":"Expression of lipoxin A4, TNF\u03b1 and IL-1\u03b2 in maternal peripheral blood, umbilical cord blood and placenta, and their significance in pre-eclampsia","volume":"33","author":"Dong","year":"2014","journal-title":"Hypertens. Pregnancy"},{"key":"10.1016\/j.plefa.2020.102203_bib0126","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/S0002-9378(98)70626-X","article-title":"The release of 15-hydroxyeicosatetraenoic acid by human placental trophoblast is increased in preeclampsia","volume":"178","author":"Johnson","year":"1998","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.plefa.2020.102203_bib0127","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1016\/0002-9378(95)90505-7","article-title":"The essential fatty acid status of mother and child in pregnancy-induced hypertension: a prospective longitudinal study","volume":"172","author":"Al","year":"1995","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.plefa.2020.102203_bib0128","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.ijgo.2015.10.024","article-title":"Association between the maternal serum levels of 19 eicosanoids and pre-eclampsia","volume":"133","author":"Long","year":"2016","journal-title":"Int. J. Gynecol. Obstet."},{"key":"10.1016\/j.plefa.2020.102203_bib0129","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1001\/jama.282.4.356","article-title":"Prostacyclin and thromboxane changes predating clinical onset of preeclampsia: A multicenter prospective study","volume":"282","author":"Mills","year":"1999","journal-title":"J. Am. Med. Assoc."},{"key":"10.1016\/j.plefa.2020.102203_bib0130","doi-asserted-by":"crossref","first-page":"3977","DOI":"10.3109\/14767058.2016.1152249","article-title":"Intrauterine growth restriction\u2013part 1","volume":"29","author":"Shastri","year":"2016","journal-title":"J. Matern. Neonatal. Med."},{"key":"10.1016\/j.plefa.2020.102203_bib0131","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajog.2020.03.006","article-title":"Expert review iron deficiency in pregnancy","author":"Georgieff","year":"2020","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.plefa.2020.102203_bib0132","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1203\/00006450-200211000-00023","article-title":"Intrauterine growth restriction is associated with changes in polyunsaturated fatty acid fetal-maternal relationships","volume":"52","year":"2002","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.plefa.2020.102203_bib0133","doi-asserted-by":"crossref","unstructured":"A.M.Marconi, E.Davoli, A.M.Baggiani, R.Fanelli, P. VFennessey, F.C.Battaglia, G.Pardi, An evaluation of fetal glucogenesis in intrauterine growth-retarded pregnancies, (1993) 860\u2013864.","DOI":"10.1016\/0026-0495(93)90060-2"},{"key":"10.1016\/j.plefa.2020.102203_bib0134","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.plefa.2017.08.011","article-title":"Fatty acid profile of maternal and fetal erythrocytes and placental expression of fatty acid transport proteins in normal and intrauterine growth restriction pregnancies","volume":"125","author":"Assump\u00e7\u00e3o","year":"2017","journal-title":"Prostaglandins Leukot. Essent. Fat. Acids"},{"key":"10.1016\/j.plefa.2020.102203_bib0135","doi-asserted-by":"crossref","first-page":"96","DOI":"10.3109\/14767058.2012.722717","article-title":"Comparison of the fatty acid composition of maternal blood and cord blood of mothers who delivered healthy full-term babies, preterm babies, and full-term small for gestational age infants","volume":"26","author":"Bobi\u0144ski","year":"2013","journal-title":"J. Matern. Neonatal. Med."},{"key":"10.1016\/j.plefa.2020.102203_bib0136","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1042\/CS20171340","article-title":"Alterations in placental long chain polyunsaturated fatty acid metabolism in human intrauterine growth restriction","volume":"132","author":"Chassen","year":"2018","journal-title":"Clin. Sci."},{"key":"10.1016\/j.plefa.2020.102203_bib0137","doi-asserted-by":"crossref","first-page":"4607","DOI":"10.1210\/jc.2003-032234","article-title":"Triglyceride hydrolase activities and expression of fatty acid binding proteins in the human placenta in pregnancies complicated by intrauterine growth restriction and diabetes, J","volume":"89","author":"Magnusson","year":"2004","journal-title":"Clin. Endocrinol. Metab."},{"key":"10.1016\/j.plefa.2020.102203_bib0138","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1203\/PDR.0b013e31818702a2","article-title":"Maternal and fetal fatty acid profile in normal and intrauterine growth restriction pregnancies with and without preeclampsia","volume":"64","author":"Alvino","year":"2008","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.plefa.2020.102203_bib0139","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1161\/HYPERTENSIONAHA.112.197897","article-title":"Preeclampsia is associated with compromised maternal synthesis of long-chain polyunsaturated fatty acids, leading to offspring deficiency","volume":"60","author":"Mackay","year":"2012","journal-title":"Hypertens"},{"key":"10.1016\/j.plefa.2020.102203_bib0140","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1042\/CS20090292","article-title":"Enhanced circulating retinol and non-esterified fatty acids in pregnancies complicated with intrauterine growth restriction","volume":"118","author":"Ortega-Senovilla","year":"2010","journal-title":"Clin. Sci."},{"key":"10.1016\/j.plefa.2020.102203_bib0141","doi-asserted-by":"crossref","first-page":"2495","DOI":"10.1080\/14767058.2016.1254182","article-title":"Lipoxin A4 (LXA4) as a potential first trimester biochemical marker of intrauterine growth disorders","volume":"30","author":"Lipa","year":"2017","journal-title":"J. Matern. Neonatal. Med."},{"key":"10.1016\/j.plefa.2020.102203_bib0142","doi-asserted-by":"crossref","first-page":"1858","DOI":"10.2337\/dc08-0039","article-title":"Maternal lipids as strong determinants of fetal environment and growth in pregnancies with gestational diabetes mellitus","volume":"31","author":"Schaefer-Graf","year":"2008","journal-title":"Diabetes Care"},{"key":"10.1016\/j.plefa.2020.102203_bib0143","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.2337\/dc12-0901","article-title":"Variation in prevalence of gestational diabetes mellitus among hospital discharges for obstetric delivery across 23 states in the United States","volume":"36","author":"Bardenheier","year":"2013","journal-title":"Diabetes Care"},{"key":"10.1016\/j.plefa.2020.102203_bib0144","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1152\/ajpregu.00342.2004","article-title":"Gender-related long-term effects in adult rats by perinatal dietary ratio of n-6\/n-3 fatty acids","volume":"288","author":"Korotkova","year":"2005","journal-title":"Am. J. Physiol. - Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.plefa.2020.102203_bib0145","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1007\/s00125-020-05136-1","article-title":"Correction to: Pregnant women with gestational diabetes and with well controlled glucose levels have decreased concentrations of individual fatty acids in maternal and cord serum","volume":"63","author":"Ortega-Senovilla","year":"2020","journal-title":"Diabetologia"},{"key":"10.1016\/j.plefa.2020.102203_bib0146","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.plefa.2016.10.006","article-title":"Fatty acid profile in cord blood of neonates born to optimally controlled gestational diabetes mellitus","volume":"115","author":"L\u00e9veill\u00e9","year":"2016","journal-title":"Prostaglandins Leukot. Essent. Fat. Acids"},{"key":"10.1016\/j.plefa.2020.102203_bib0147","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1016\/j.jnutbio.2013.03.003","article-title":"Gestational diabetes mellitus decreases placental uptake of long-chain polyunsaturated fatty acids: Involvement of long-chain acyl-CoA synthetase","volume":"24","author":"Ara\u00fajo","year":"2013","journal-title":"J. Nutr. Biochem."},{"key":"10.1016\/j.plefa.2020.102203_bib0148","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/s00125-003-1275-5","article-title":"Adverse effect of obesity on red cell membrane arachidonic and docosahexaenoic acids in gestational diabetes","volume":"47","author":"Min","year":"2004","journal-title":"Diabetologia"},{"key":"10.1016\/j.plefa.2020.102203_bib0149","doi-asserted-by":"crossref","first-page":"1492","DOI":"10.1038\/sj.ejcn.1601996","article-title":"Plasma AA and DHA levels are not compromised in newly diagnosed gestational diabetic women","volume":"58","author":"Thomas","year":"2004","journal-title":"Eur. J. Clin. Nutr."},{"key":"10.1016\/j.plefa.2020.102203_bib0150","doi-asserted-by":"crossref","first-page":"120","DOI":"10.2337\/dc08-0679","article-title":"Gestational diabetes mellitus upsets the proportion of fatty acids in umbilical arterial but not venous plasma","volume":"32","author":"Ortega-Senovilla","year":"2009","journal-title":"Diabetes Care"},{"key":"10.1016\/j.plefa.2020.102203_bib0151","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1007\/s11745-006-5104-8","article-title":"Gestational diabetes mellitus enhances arachidonic and docosahexaenoic acids in placental phospholipids","volume":"41","author":"Bitsanis","year":"2006","journal-title":"Lipids"},{"key":"10.1016\/j.plefa.2020.102203_bib0152","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pmed.1002910","article-title":"Plasma phospholipid n-3 and n-6 polyunsaturated fatty acids in relation to cardiometabolic markers and gestational diabetes: A longitudinal study within the prospective NICHD Fetal Growth Studies","volume":"16","author":"Zhu","year":"2019","journal-title":"PLoS Med."},{"key":"10.1016\/j.plefa.2020.102203_bib0153","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1111\/dme.12978","article-title":"Longitudinal circulating concentrations of long-chain polyunsaturated fatty acids in the third trimester of pregnancy in gestational diabetes","volume":"33","author":"Zhao","year":"2016","journal-title":"Diabet. Med."},{"key":"10.1016\/j.plefa.2020.102203_bib0154","doi-asserted-by":"crossref","first-page":"2049","DOI":"10.2337\/dc10-0693","article-title":"Differences in maternal circulating fatty acid composition and dietary fat intake in women with gestational diabetes mellitus or mild gestational hyperglycemia","volume":"33","author":"Chen","year":"2010","journal-title":"Diabetes Care"},{"key":"10.1016\/j.plefa.2020.102203_bib0155","first-page":"305","article-title":"Materno-fetal transfer of docosahexaenoic acid is impaired by gestational diabetes mellitus","author":"Pag\u00e1n","year":"2013","journal-title":"Am. J. Physiol. - Endocrinol. Metab."},{"key":"10.1016\/j.plefa.2020.102203_bib0156","doi-asserted-by":"crossref","unstructured":"S.G.Kuper, A.R.Abramovici, V.C.Jauk, L.M.Harper, J.R.Biggio, A.T.Tita, By smoking status, 217 (2018) 1\u201311. 10.1016\/j.ajog.2017.05.033.The.","DOI":"10.1016\/j.ajog.2017.05.033"},{"key":"10.1016\/j.plefa.2020.102203_bib0157","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1515\/jpm-2016-0037","article-title":"The effect of fish oil supplementation on maternal and neonatal outcomes: A triple-blind, randomized controlled trial","volume":"45","author":"Ostadrahimi","year":"2017","journal-title":"J. Perinat. Med."},{"key":"10.1016\/j.plefa.2020.102203_bib0158","doi-asserted-by":"crossref","first-page":"808","DOI":"10.3945\/ajcn.112.050021","article-title":"DHA supplementation and pregnancy outcomes","volume":"97","author":"Carlson","year":"2013","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.plefa.2020.102203_bib0159","doi-asserted-by":"crossref","first-page":"8024","DOI":"10.3390\/ijms15058024","article-title":"Docosahexaenoic acid supplementation during pregnancy: A potential tool to prevent membrane rupture and preterm labor","volume":"15","author":"Pietrantoni","year":"2014","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.plefa.2020.102203_bib0160","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1111\/j.1471-0528.2000.tb13235.x","article-title":"Randomised clinical trials of fish oil supplementation in high risk pregnancies","volume":"107","author":"Olsen","year":"2000","journal-title":"BJOG An Int. J. Obstet. Gynaecol."},{"key":"10.1016\/j.plefa.2020.102203_bib0161","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1056\/NEJMoa1816832","article-title":"A randomized trial of prenatal n\u22123 fatty acid supplementation and preterm delivery","volume":"381","author":"Makrides","year":"2019","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.plefa.2020.102203_bib0162","first-page":"1","volume":"210","author":"Caritis","year":"2015","journal-title":"NIH Public Access"},{"key":"10.1016\/j.plefa.2020.102203_bib0163","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1136\/jech.47.6.436","article-title":"Frequency of seafood intake in pregnancy as a determinant of birth weight: Evidence for a dose dependent relationship","volume":"47","author":"Olsen","year":"1993","journal-title":"J. Epidemiol. Community Health"},{"key":"10.1016\/j.plefa.2020.102203_bib0164","doi-asserted-by":"crossref","first-page":"2017","DOI":"10.3109\/14767058.2015.1072163","article-title":"Fish oil supplementation improves pregnancy outcomes and size of the newborn: A meta-analysis of 21 randomized controlled trials","volume":"29","author":"Chen","year":"2016","journal-title":"J. Matern. Neonatal. Med."},{"key":"10.1016\/j.plefa.2020.102203_bib0165","article-title":"Omega-3 fatty acid addition during pregnancy","volume":"11","author":"Middleton","year":"2018","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.plefa.2020.102203_bib0166","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1093\/jn\/nxy204","article-title":"Fish oil supplementation in pregnancy increases gestational age, size for gestational age, and birth weight in infants: A randomized controlled trial","volume":"149","author":"Vinding","year":"2019","journal-title":"J. Nutr."},{"key":"10.1016\/j.plefa.2020.102203_bib0167","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1038\/sj.ejcn.1602609","article-title":"Duration of pregnancy in relation to fish oil supplementation and habitual fish intake: A randomised clinical trial with fish oil","volume":"61","author":"Olsen","year":"2007","journal-title":"Eur. J. Clin. Nutr."},{"key":"10.1016\/j.plefa.2020.102203_bib0168","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1016\/0140-6736(92)90533-9","article-title":"Randomised controlled trial of effect of fish-oil supplementation on pregnancy duration","volume":"339","author":"Olsen","year":"1992","journal-title":"Lancet"},{"key":"10.1016\/j.plefa.2020.102203_bib0169","first-page":"469","article-title":"A randomized trial of docosahexaenoic acid supplementation during the third trimester of pregnancy","volume":"101","author":"Smuts","year":"2003","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.plefa.2020.102203_bib0170","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1017\/S0007114511000961","article-title":"Consumption of a DHA-containing functional food during pregnancy is associated with lower infant ponderal index and cord plasma insulin concentration","volume":"106","author":"Courville","year":"2011","journal-title":"Br. J. Nutr."},{"key":"10.1016\/j.plefa.2020.102203_bib0171","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1177\/15648265100312S203","article-title":"Effects of docosahexaenoic acid supplementation during pregnancy on gestational age and size at birth: Randomized, double-blind, placebo-controlled trial in Mexico","volume":"31","author":"Ramakrishnan","year":"2010","journal-title":"Food Nutr. Bull."},{"key":"10.1016\/j.plefa.2020.102203_bib0172","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1097\/AOG.0b013e3181cbd60e","article-title":"Omega-3 fatty acid supplementation to prevent recurrent preterm birth: A randomized controlled trial","volume":"115","author":"Harper","year":"2010","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.plefa.2020.102203_bib0173","doi-asserted-by":"crossref","DOI":"10.1542\/peds.108.5.e82","article-title":"Similar effects on infants of n-3 and n-6 fatty acids supplementation to pregnant and lactating women","volume":"108","author":"Helland","year":"2001","journal-title":"Pediatrics"},{"key":"10.1016\/j.plefa.2020.102203_bib0174","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1136\/fn.88.5.F383","article-title":"Maternal docosahexaenoic acid supplementation during pregnancy and visual evoked potential development in term infants: A double blind, prospective, randomised trial","volume":"88","author":"Malcolm","year":"2003","journal-title":"Arch. Dis. Child. Fetal Neonatal. Ed."},{"key":"10.1016\/j.plefa.2020.102203_bib0175","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1111\/j.1471-0528.1995.tb09059.x","article-title":"A randomised double blind placebo controlled trial of fish oil in high risk pregnancy","volume":"102","author":"Onwude","year":"1995","journal-title":"BJOG An Int. J. Obstet. Gynaecol."},{"key":"10.1016\/j.plefa.2020.102203_bib0176","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1007\/S11745-000-0602-2","article-title":"Fetal erythrocyte phospholipid polyunsaturated fatty acids are altered in pregnancy complicated with gestational diabetes mellitus","volume":"35","author":"Wijendran","year":"2000","journal-title":"Lipids"},{"key":"10.1016\/j.plefa.2020.102203_bib0177","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/j.clnu.2014.06.005","article-title":"Effects of omega-3 fatty acid supplementation on insulin metabolism and lipid profiles in gestational diabetes: Randomized, double-blind, placebo-controlled trial","volume":"34","author":"Samimi","year":"2015","journal-title":"Clin. Nutr."},{"key":"10.1016\/j.plefa.2020.102203_bib0178","doi-asserted-by":"crossref","unstructured":"F.Lalooha, T.D.Ghaleh, H.Pakniiat, F.Ranjkesh, Evaluation of the effect of omega-3 supplements in the prevention of preeclampsia among high risk women, 6 (2012) 2580\u20132583. 10.5897\/AJPP11.836.","DOI":"10.5897\/AJPP11.836"},{"key":"10.1016\/j.plefa.2020.102203_bib0179","first-page":"585","article-title":"Prevention of preeclampsia by linoleic acid and calcium supplementation: A randomized controlled trial","volume":"91","author":"Herrera M.","year":"1998","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.plefa.2020.102203_bib0180","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1300\/J013v19n02_07","article-title":"Effects of a combination of evening primrose oil (Gamma linolenic acid) and fish oil (eicosapentaenoic\u00a0+\u00a0docahexaenoic acid) versus magnesium, and versus placebo in preventing pre-eclampsia","volume":"19","author":"D\u2019Almeida","year":"1992","journal-title":"Women Heal."},{"key":"10.1016\/j.plefa.2020.102203_bib0181","doi-asserted-by":"crossref","first-page":"1378","DOI":"10.3945\/ajcn.111.033217","article-title":"Fish-oil supplementation in pregnancy does not reduce the risk of gestational diabetes or preeclampsia","volume":"95","author":"Zhou","year":"2012","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.plefa.2020.102203_bib0182","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.ejogrb.2017.01.002","article-title":"Evaluation of the effectiveness of low-dose aspirin and omega 3 in treatment of asymmetrically intrauterine growth restriction: A randomized clinical trial","volume":"210","author":"Ali","year":"2017","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"key":"10.1016\/j.plefa.2020.102203_bib0183","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1111\/j.1471-0528.1995.tb09064.x","article-title":"The effects of 3g eicosapentaenoic acid daily on recurrence of intrauterine growth retardation and pregnancy induced hypertension","volume":"102","author":"Bulstra-Ramakers","year":"1995","journal-title":"BJOG An Int. J. Obstet. Gynaecol."},{"key":"10.1016\/j.plefa.2020.102203_bib0184","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1186\/s12884-019-2450-0","article-title":"The REVAMP study: research exploring various aspects and mechanisms in preeclampsia: study protocol","volume":"19","author":"Wadhwani","year":"2019","journal-title":"BMC Pregnancy Childbirth"}],"container-title":["Prostaglandins, Leukotrienes and Essential Fatty Acids"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0952327820301617?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0952327820301617?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T05:14:41Z","timestamp":1778562881000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0952327820301617"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12]]},"references-count":184,"alternative-id":["S0952327820301617"],"URL":"https:\/\/doi.org\/10.1016\/j.plefa.2020.102203","relation":{},"ISSN":["0952-3278"],"issn-type":[{"value":"0952-3278","type":"print"}],"subject":[],"published":{"date-parts":[[2020,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Exploring the role of LC-PUFA metabolism in pregnancy complications","name":"articletitle","label":"Article Title"},{"value":"Prostaglandins, Leukotrienes and Essential Fatty Acids","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.plefa.2020.102203","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"102203"}}