{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T05:17:16Z","timestamp":1784697436687,"version":"3.55.0"},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,7,24]],"date-time":"2022-07-24T00:00:00Z","timestamp":1658620800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","plefa.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Prostaglandins, Leukotrienes and Essential Fatty Acids"],"published-print":{"date-parts":[[2022,9]]},"DOI":"10.1016\/j.plefa.2022.102474","type":"journal-article","created":{"date-parts":[[2022,7,23]],"date-time":"2022-07-23T10:20:34Z","timestamp":1658571634000},"page":"102474","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Levels of eicosanoids in nasal secretions associated with nasal polyp severity in chronic rhinosinusitis"],"prefix":"10.1016","volume":"184","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2314-3322","authenticated-orcid":false,"given":"Axel","family":"Nordstr\u00f6m","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mattias","family":"Jangard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Svedberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Ryott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Kumlin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"Suppl S29","key":"10.1016\/j.plefa.2022.102474_bib0001","first-page":"1","article-title":"European position paper on rhinosinusitis and nasal polyps 2020","volume":"58","author":"Fokkens","year":"2020","journal-title":"Rhinology"},{"key":"10.1016\/j.plefa.2022.102474_bib0002","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1038\/s41572-020-00218-1","article-title":"Adult chronic rhinosinusitis","volume":"6","author":"Bachert","year":"2020","journal-title":"Nat. Rev. Dis. Primers"},{"key":"10.1016\/j.plefa.2022.102474_bib0003","doi-asserted-by":"crossref","first-page":"925","DOI":"10.3390\/jcm9040925","article-title":"Associations between the quality of life and nasal polyp size in patients suffering from chronic rhinosinusitis without nasal polyps, with nasal polyps or aspirin-exacerbated respiratory disease","volume":"9","author":"Schneider","year":"2020","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.plefa.2022.102474_bib0004","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1016\/j.jaip.2016.12.027","article-title":"Clinical characteristics of patients with chronic rhinosinusitis with nasal polyps, asthma, and aspirin-exacerbated respiratory disease","volume":"5","author":"Stevens","year":"2017","journal-title":"J. Allergy Clin. Immunol. Pract."},{"key":"10.1016\/j.plefa.2022.102474_bib0005","doi-asserted-by":"crossref","first-page":"e97581","DOI":"10.1371\/journal.pone.0097581","article-title":"Mixed T helper cell signatures in chronic rhinosinusitis with and without polyps","volume":"9","author":"Derycke","year":"2014","journal-title":"PLoS ONE"},{"key":"10.1016\/j.plefa.2022.102474_bib0006","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1016\/j.jaci.2015.12.1324","article-title":"Inflammatory endotypes of chronic rhinosinusitis based on cluster analysis of biomarkers","volume":"137","author":"Tomassen","year":"2016","journal-title":"J. Allergy Clin. Immunol.."},{"key":"10.1016\/j.plefa.2022.102474_bib0007","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1111\/cea.12472","article-title":"Pathogenesis of nasal polyposis","volume":"45","author":"Hulse","year":"2015","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.plefa.2022.102474_bib0008","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1016\/j.jaci.2010.07.007","article-title":"Presence of IL-5 protein and IgE antibodies to staphylococcal enterotoxins in nasal polyps is associated with comorbid asthma","volume":"126","author":"Bachert","year":"2010","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.plefa.2022.102474_bib0009","doi-asserted-by":"crossref","first-page":"192","DOI":"10.2500\/ajra.2014.28.4033","article-title":"Differences in initial immunoprofiles between recurrent and nonrecurrent chronic rhinosinusitis with nasal polyps","volume":"28","author":"Van Zele","year":"2014","journal-title":"Am. J. Rhinol. Allergy"},{"key":"10.1016\/j.plefa.2022.102474_bib0010","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1042\/EBC20190083","article-title":"Eicosanoids","volume":"64","author":"Calder","year":"2020","journal-title":"Essays Biochem."},{"key":"10.1016\/j.plefa.2022.102474_bib0011","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1111\/all.13726","article-title":"Dysregulated fatty acid metabolism in nasal polyp-derived eosinophils from patients with chronic rhinosinusitis","volume":"74","author":"Miyata","year":"2019","journal-title":"Allergy"},{"key":"10.1016\/j.plefa.2022.102474_bib0012","doi-asserted-by":"crossref","DOI":"10.1016\/j.plefa.2020.102218","article-title":"Altered tissue specialized pro-resolving mediators in chronic rhinosinusitis","volume":"164","author":"Vickery","year":"2021","journal-title":"Prostaglandins Leukot. Essent. Fatty Acids"},{"key":"10.1016\/j.plefa.2022.102474_bib0013","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.1016\/j.jaci.2015.10.020","article-title":"Thymic stromal lymphopoietin controls prostaglandin D2 generation in patients with aspirin-exacerbated respiratory disease","volume":"137","author":"Buchheit","year":"2016","journal-title":"J. Allergy Clin. Immunol.."},{"key":"10.1016\/j.plefa.2022.102474_bib0014","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1186\/s12931-014-0100-7","article-title":"Prostaglandin E2 receptors in asthma and in chronic rhinosinusitis\/nasal polyps with and without aspirin hypersensitivity","volume":"15","author":"Machado-Carvalho","year":"2014","journal-title":"Respir. Res."},{"key":"10.1016\/j.plefa.2022.102474_bib0015","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1016\/j.jaci.2005.02.029","article-title":"Prostaglandin, leukotriene, and lipoxin balance in chronic rhinosinusitis with and without nasal polyposis","volume":"115","author":"P\u00e9rez-Novo","year":"2005","journal-title":"J. Allergy Clin. Immunol.."},{"key":"10.1016\/j.plefa.2022.102474_bib0016","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1164\/ajrccm\/146.1.96","article-title":"Urinary excretion of leukotriene E4 and 11-dehydro-thromboxane B2 in response to bronchial provocations with allergen, aspirin, leukotriene D4, and histamine in asthmatics","volume":"146","author":"Kumlin","year":"1992","journal-title":"Am. Rev. Respir. Dis."},{"key":"10.1016\/j.plefa.2022.102474_bib0017","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/j.jaip.2016.03.004","article-title":"Diagnostic utility of urinary LTE4 in asthma, allergic rhinitis, chronic rhinosinusitis, nasal polyps, and aspirin sensitivity","volume":"4","author":"Divekar","year":"2016","journal-title":"J. Allergy Clin. Immunol. Pract."},{"key":"10.1016\/j.plefa.2022.102474_bib0018","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1164\/rccm.201909-1869OC","article-title":"Urinary leukotriene E(4) and prostaglandin D(2) metabolites increase in adult and childhood severe asthma characterized by type 2 inflammation. A clinical observational study","volume":"203","author":"Kolmert","year":"2021","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.plefa.2022.102474_bib0019","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1177\/01945998211011060","article-title":"Urine leukotriene E4: implications as a biomarker in chronic rhinosinusitis","volume":"166","author":"Choby","year":"2022","journal-title":"Otolaryngol. Head Neck Surg."},{"key":"10.1016\/j.plefa.2022.102474_bib0020","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1177\/0194599819871700","article-title":"Establishing urinary leukotriene E(4) as a diagnostic biomarker for chronic rhinosinusitis with comorbid asthma and atopy","volume":"161","author":"Santarelli","year":"2019","journal-title":"Otolaryngol. Head Neck Surg."},{"key":"10.1016\/j.plefa.2022.102474_bib0021","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1002\/lary.29137","article-title":"Elevated urine leukotriene E4 is associated with worse objective markers in nasal polyposis patients","volume":"131","author":"Choby","year":"2021","journal-title":"Laryngoscope"},{"key":"10.1016\/j.plefa.2022.102474_bib0022","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1002\/alr.22632","article-title":"Machine learning of biomarkers and clinical observation to predict eosinophilic chronic rhinosinusitis: a pilot study","volume":"11","author":"Thorwarth","year":"2021","journal-title":"Int. Forum Allergy Rhinol."},{"key":"10.1016\/j.plefa.2022.102474_bib0023","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1016\/S2213-2600(21)00097-7","article-title":"Mepolizumab for chronic rhinosinusitis with nasal polyps (SYNAPSE): a randomised, double-blind, placebo-controlled, phase 3 trial","volume":"9","author":"Han","year":"2021","journal-title":"Lancet Respir. Med."},{"key":"10.1016\/j.plefa.2022.102474_bib0024","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/j.jaci.2020.01.020","article-title":"Biologics for chronic rhinosinusitis with nasal polyps","volume":"145","author":"Bachert","year":"2020","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.plefa.2022.102474_bib0025","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1016\/j.jaci.2021.05.043","article-title":"Mepolizumab targets multiple immune cells in aspirin-exacerbated respiratory disease","volume":"148","author":"Buchheit","year":"2021","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.plefa.2022.102474_bib0026","doi-asserted-by":"crossref","first-page":"AB185","DOI":"10.1016\/j.jaci.2019.12.324","article-title":"Dupilumab reduces blood, urine, and nasal biomarkers of type 2 inflammation in patients with chronic rhinosinusitis with nasal polyps in the phase 3 SINUS-52 trial","volume":"145","author":"Bachert","year":"2020","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.plefa.2022.102474_bib0027","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4193\/Rhino12.000","article-title":"European position paper on rhinosinusitis and nasal polyps 2012. A summary for otorhinolaryngologists","volume":"50","author":"Fokkens","year":"2012","journal-title":"Rhinology"},{"key":"10.1016\/j.plefa.2022.102474_bib0028","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1007\/s00405-018-5248-1","article-title":"Updated Sniffin' sticks normative data based on an extended sample of 9139 subjects","volume":"276","author":"Oleszkiewicz","year":"2019","journal-title":"Eur. Arch. Otorhinolaryngol."},{"key":"10.1016\/j.plefa.2022.102474_bib0029","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1016\/j.rmed.2014.02.005","article-title":"Current evidence and future research needs for FeNO measurement in respiratory diseases","volume":"108","author":"Bjermer","year":"2014","journal-title":"Respir. Med."},{"key":"10.1016\/j.plefa.2022.102474_bib0030","first-page":"91","article-title":"A comparison of computerized tomographic staging systems in chronic sinusitis","volume":"21","author":"Oluwole","year":"1996","journal-title":"Clin. Otolaryngol. Allied Sci."},{"key":"10.1016\/j.plefa.2022.102474_bib0031","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.jaci.2006.09.005","article-title":"Rhinosinusitis: developing guidance for clinical trials","volume":"118","author":"Meltzer","year":"2006","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.plefa.2022.102474_bib0032","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1136\/thx.2008.101196","article-title":"Increased levels of cysteinyl-leukotrienes in saliva, induced sputum, urine and blood from patients with aspirin-intolerant asthma","volume":"63","author":"Gaber","year":"2008","journal-title":"Thorax"},{"key":"10.1016\/j.plefa.2022.102474_bib0033","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/S0091-6749(96)70167-7","article-title":"Increased urinary excretion of the prostaglandin D2 metabolite 9 alpha, 11 beta-prostaglandin F2 after aspirin challenge supports mast cell activation in aspirin-induced airway obstruction","volume":"98","author":"O'Sullivan","year":"1996","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.plefa.2022.102474_bib0034","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1111\/all.13411","article-title":"Multidimensional endotypes of chronic rhinosinusitis and their association with treatment outcomes","volume":"73","author":"Liao","year":"2018","journal-title":"Allergy"},{"key":"10.1016\/j.plefa.2022.102474_bib0035","doi-asserted-by":"crossref","first-page":"82","DOI":"10.2500\/ar.2015.6.0120","article-title":"Commentary on gender differences in prevalence, treatment, and quality of life of patients with chronic rhinosinusitis","volume":"6","author":"Ference","year":"2015","journal-title":"Allergy Rhinol. (Providence)"},{"key":"10.1016\/j.plefa.2022.102474_bib0036","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1111\/j.1365-2222.2004.1912.x","article-title":"Urinary leukotriene E4 and 9 alpha, 11 beta-prostaglandin F concentrations in mild, moderate and severe asthma, and in healthy subjects","volume":"34","author":"Misso","year":"2004","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.plefa.2022.102474_bib0037","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1183\/09031936.03.00113403","article-title":"Evidence of mast cell activation and leukotriene release after mannitol inhalation","volume":"22","author":"Brannan","year":"2003","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.plefa.2022.102474_bib0038","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1046\/j.1365-2222.1998.00368.x","article-title":"Urinary excretion of inflammatory mediators during allergen-induced early and late phase asthmatic reactions","volume":"28","author":"O'Sullivan","year":"1998","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.plefa.2022.102474_bib0039","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1164\/ajrccm\/143.5_Pt_1.1025","article-title":"Urinary leukotriene E4 concentrations increase after aspirin challenge in aspirin-sensitive asthmatic subjects","volume":"143","author":"Christie","year":"1991","journal-title":"Am. Rev. Respir. Dis."},{"key":"10.1016\/j.plefa.2022.102474_bib0040","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1183\/09031936.93.06071018","article-title":"The leukotriene-receptor antagonist MK-0679 blocks airway obstruction induced by inhaled lysine-aspirin in aspirin-sensitive asthmatics","volume":"6","author":"Dahl\u00e9n","year":"1993","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.plefa.2022.102474_bib0041","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1111\/j.1398-9995.2001.00913.x","article-title":"Possible involvement of mast-cell activation in aspirin provocation of aspirin-induced asthma","volume":"56","author":"Mita","year":"2001","journal-title":"Allergy"},{"key":"10.1016\/j.plefa.2022.102474_bib0042","first-page":"162","article-title":"Urinary LTE4 is higher after nasal provocation test with L-ASA in bronchial than in only nasal responders","volume":"39","author":"Micheletto","year":"2007","journal-title":"Eur. Ann. Allergy Clin. Immunol."},{"key":"10.1016\/j.plefa.2022.102474_bib0043","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.jaci.2008.09.005","article-title":"Clinical course and urinary eicosanoids in patients with aspirin-induced urticaria followed up for 4 years","volume":"123","author":"Setkowicz","year":"2009","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.plefa.2022.102474_bib0044","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1111\/cea.13129","article-title":"Complex association patterns for inflammatory mediators in induced sputum from subjects with asthma","volume":"48","author":"Hastie","year":"2018","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.plefa.2022.102474_bib0045","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1016\/j.jaci.2020.11.001","article-title":"Inflammatory heterogeneity in aspirin-exacerbated respiratory disease","volume":"147","author":"Scott","year":"2021","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.plefa.2022.102474_bib0046","doi-asserted-by":"crossref","first-page":"28517","DOI":"10.3402\/ecrj.v2.28517","article-title":"Application of nitric oxide measurements in clinical conditions beyond asthma","volume":"2","author":"Malinovschi","year":"2015","journal-title":"Eur. Clin. Respir. J."},{"key":"10.1016\/j.plefa.2022.102474_bib0047","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1016\/S2213-2600(21)00124-7","article-title":"Baseline FeNO as a prognostic biomarker for subsequent severe asthma exacerbations in patients with uncontrolled, moderate-to-severe asthma receiving placebo in the liberty asthma quest study: a post-hoc analysis","volume":"9","author":"Busse","year":"2021","journal-title":"Lancet Respir. Med."},{"key":"10.1016\/j.plefa.2022.102474_bib0048","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1056\/NEJMra2032506","article-title":"Biologic therapies for severe asthma","volume":"386","author":"Brusselle","year":"2022","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.plefa.2022.102474_bib0049","doi-asserted-by":"crossref","first-page":"3537","DOI":"10.4049\/jimmunol.1500905","article-title":"Aspirin-exacerbated respiratory disease involves a cysteinyl leukotriene-driven IL-33-mediated mast cell activation pathway","volume":"195","author":"Liu","year":"2015","journal-title":"J. Immunol."},{"key":"10.1016\/j.plefa.2022.102474_bib0050","first-page":"544","article-title":"Endotypes of chronic rhinosinusitis with nasal polyps with and without NSAID \u00e2\u20ac\" intolerance","volume":"58","author":"Steiner","year":"2020","journal-title":"Rhinology"},{"key":"10.1016\/j.plefa.2022.102474_bib0051","doi-asserted-by":"crossref","first-page":"E304","DOI":"10.1002\/lary.27112","article-title":"Olfactory and middle meatal cytokine levels correlate with olfactory function in chronic rhinosinusitis","volume":"128","author":"Wu","year":"2018","journal-title":"Laryngoscope"},{"key":"10.1016\/j.plefa.2022.102474_bib0052","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1002\/alr.22770","article-title":"Olfactory cleft mucus inflammatory proteins in CRS: a case-control study","volume":"11","author":"Smith","year":"2021","journal-title":"Int. Forum Allergy Rhinol."},{"key":"10.1016\/j.plefa.2022.102474_bib0053","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1080\/14712598.2020.1714027","article-title":"Anti-IL-4\/IL-13 for the treatment of asthma: the story so far","volume":"20","author":"Moran","year":"2020","journal-title":"Expert Opin. Biol. Ther."},{"key":"10.1016\/j.plefa.2022.102474_bib0054","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.1016\/j.jaci.2018.02.002","article-title":"Identification of clinically relevant chronic rhinosinusitis endotypes using cluster analysis of mucus cytokines","volume":"141","author":"Turner","year":"2018","journal-title":"J. Allergy Clin. Immunol."}],"container-title":["Prostaglandins, Leukotrienes and Essential Fatty Acids"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0952327822000862?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0952327822000862?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T08:11:42Z","timestamp":1760602302000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0952327822000862"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9]]},"references-count":54,"alternative-id":["S0952327822000862"],"URL":"https:\/\/doi.org\/10.1016\/j.plefa.2022.102474","relation":{},"ISSN":["0952-3278"],"issn-type":[{"value":"0952-3278","type":"print"}],"subject":[],"published":{"date-parts":[[2022,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Levels of eicosanoids in nasal secretions associated with nasal polyp severity in chronic rhinosinusitis","name":"articletitle","label":"Article Title"},{"value":"Prostaglandins, Leukotrienes and Essential Fatty Acids","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.plefa.2022.102474","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"102474"}}