{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,12]],"date-time":"2026-11-12T19:09:24Z","timestamp":1794510564530,"version":"4.9.1"},"reference-count":79,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Physical Medicine and Rehabilitation Clinics of North America"],"published-print":{"date-parts":[[2023,11]]},"DOI":"10.1016\/j.pmr.2023.05.002","type":"journal-article","created":{"date-parts":[[2023,7,20]],"date-time":"2023-07-20T00:25:02Z","timestamp":1689812702000},"page":"783-798","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":46,"title":["Hypertrophic Scar"],"prefix":"10.1016","volume":"34","author":[{"given":"Shyla Kajal","family":"Bharadia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lindsay","family":"Burnett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Gabriel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.pmr.2023.05.002_bib1","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1097\/BCR.0000000000000257","article-title":"Long-term outcomes in patients surviving large burns: the musculoskeletal system","volume":"37","author":"Holavanahalli","year":"2016","journal-title":"J\u00a0Burn Care Res"},{"issue":"4","key":"10.1016\/j.pmr.2023.05.002_bib2","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1097\/BCR.0b013e3181e4ca62","article-title":"Long-term outcomes in patients surviving large burns: the skin","volume":"31","author":"Holavanahalli","year":"2010","journal-title":"J\u00a0Burn Care Res"},{"issue":"2","key":"10.1016\/j.pmr.2023.05.002_bib3","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.jpsychores.2007.09.003","article-title":"From survival to socialization: a longitudinal study of body image in survivors of severe burn injury","volume":"64","author":"Thombs","year":"2008","journal-title":"J\u00a0Psychosom Res"},{"issue":"3","key":"10.1016\/j.pmr.2023.05.002_bib4","doi-asserted-by":"crossref","first-page":"606","DOI":"10.3390\/ijms18030606","article-title":"Keloid and hypertrophic scars are the result of chronic inflammation in the reticular dermis","volume":"18","author":"Ogawa","year":"2017","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.pmr.2023.05.002_bib5","doi-asserted-by":"crossref","unstructured":"Karppinen S.M., Heljasvaara R., Gullberg D., et al., Toward understanding scarless skin wound healing and pathological scarring. F1000Res. 2019;8:F1000 Faculty Rev-787. https:\/\/doi.org\/10.12688\/f1000research.18293.1.","DOI":"10.12688\/f1000research.18293.1"},{"issue":"4","key":"10.1016\/j.pmr.2023.05.002_bib6","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/S0305-4179(03)00067-6","article-title":"What is the prevalence of hypertrophic scarring following burns?","volume":"29","author":"Bombaro","year":"2003","journal-title":"Burns"},{"issue":"3","key":"10.1016\/j.pmr.2023.05.002_bib7","first-page":"215","article-title":"The cost of post-burn scarring","volume":"28","author":"Mirastschijski","year":"2015","journal-title":"Ann Burns Fire Disasters"},{"issue":"6","key":"10.1016\/j.pmr.2023.05.002_bib8","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1097\/01.BCR.0000245652.26648.36","article-title":"Quality of life after burn injury: the impact of joint contracture","volume":"27","author":"Leblebici","year":"2006","journal-title":"J\u00a0Burn Care Res"},{"key":"10.1016\/j.pmr.2023.05.002_bib9","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1097\/JDN.0b013e3182274a98","article-title":"Anatomy and Physiology of the Skin","volume":"3","author":"Kolarsick","year":"2011","journal-title":"Journal of the Dermatology Nurses' Association"},{"issue":"3","key":"10.1016\/j.pmr.2023.05.002_bib10","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.clindermatol.2011.08.007","article-title":"Structure and function of the epidermis related to barrier properties","volume":"30","author":"Baroni","year":"2012","journal-title":"Clin Dermatol"},{"issue":"8","key":"10.1016\/j.pmr.2023.05.002_bib11","doi-asserted-by":"crossref","first-page":"1811","DOI":"10.3390\/ijms20081811","article-title":"The dynamics of the skin's immune system","volume":"20","author":"Nguyen","year":"2019","journal-title":"Int J Mol Sci"},{"issue":"2","key":"10.1016\/j.pmr.2023.05.002_bib12","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.hcl.2016.12.004","article-title":"Biological principles of scar and contracture","volume":"33","author":"Kwan","year":"2017","journal-title":"Hand Clin"},{"issue":"1","key":"10.1016\/j.pmr.2023.05.002_bib13","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1002\/jcp.10474","article-title":"Site-matched papillary and reticular human dermal fibroblasts differ in their release of specific growth factors\/cytokines and in their interaction with keratinocytes","volume":"200","author":"Sorrell","year":"2004","journal-title":"J\u00a0Cell Physiol"},{"issue":"1","key":"10.1016\/j.pmr.2023.05.002_bib14","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1159\/000339613","article-title":"Wound repair and regeneration","volume":"49","author":"Reinke","year":"2012","journal-title":"Eur Surg Res"},{"issue":"7","key":"10.1016\/j.pmr.2023.05.002_bib15","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1016\/j.imbio.2011.01.001","article-title":"Macrophages in skin injury and repair","volume":"216","author":"Mahdavian Delavary","year":"2011","journal-title":"Immunobiology"},{"issue":"2","key":"10.1016\/j.pmr.2023.05.002_bib16","doi-asserted-by":"crossref","first-page":"897","DOI":"10.3390\/ijms22020897","article-title":"Molecular changes underlying hypertrophic scarring following burns involve specific deregulations at all wound healing stages (inflammation, proliferation and maturation)","volume":"22","author":"\u010coma","year":"2021","journal-title":"Int J Mol Sci"},{"issue":"1","key":"10.1016\/j.pmr.2023.05.002_bib17","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1097\/01.ASW.0000547415.38888.c4","article-title":"Duration of scar maturation: retrospective analyses of 361 hypertrophic scars over 5 years","volume":"32","author":"Kant","year":"2019","journal-title":"Adv Skin Wound Care"},{"issue":"5","key":"10.1016\/j.pmr.2023.05.002_bib18","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1111\/1523-1747.ep12606979","article-title":"Increased types I and III collagen and transforming growth factor-beta 1 mRNA and protein in hypertrophic burn scar","volume":"104","author":"Zhang","year":"1995","journal-title":"J\u00a0Invest Dermatol"},{"issue":"5","key":"10.1016\/j.pmr.2023.05.002_bib19","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1111\/j.1365-2559.1995.tb00249.x","article-title":"Immunohistochemical localization of the proteoglycans decorin, biglycan and versican and transforming growth factor-beta in human post-burn hypertrophic and mature scars","volume":"26","author":"Scott","year":"1995","journal-title":"Histopathology"},{"issue":"2","key":"10.1016\/j.pmr.2023.05.002_bib20","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1097\/BCR.0b013e3182335980","article-title":"Reduced decorin, fibromodulin, and transforming growth factor-\u03b23 in deep dermis leads to hypertrophic scarring","volume":"33","author":"Honardoust","year":"2012","journal-title":"J\u00a0Burn Care Res"},{"key":"10.1016\/j.pmr.2023.05.002_bib21","series-title":"Herndon, DN. Total burn care","first-page":"455","article-title":"Molecular and cellular basis of hypertrophic scarring","author":"Kwan","year":"2018"},{"issue":"5","key":"10.1016\/j.pmr.2023.05.002_bib22","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/j.burns.2006.08.018","article-title":"Recombinant human decorin inhibits cell proliferation and downregulates TGF-beta1 production in hypertrophic scar fibroblasts","volume":"33","author":"Zhang","year":"2007","journal-title":"Burns"},{"issue":"4","key":"10.1016\/j.pmr.2023.05.002_bib23","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.burns.2008.08.021","article-title":"Recombinant human decorin inhibits TGF-beta1-induced contraction of collagen lattice by hypertrophic scar fibroblasts","volume":"35","author":"Zhang","year":"2009","journal-title":"Burns"},{"issue":"1","key":"10.1016\/j.pmr.2023.05.002_bib24","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1097\/00042728-200501000-00010","article-title":"Objective assessment of burn scar vascularity, erythema, pliability, thickness, and planimetry","volume":"31","author":"Oliveira","year":"2005","journal-title":"Dermatol Surg"},{"issue":"2","key":"10.1016\/j.pmr.2023.05.002_bib25","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/S0749-0712(21)00203-1","article-title":"Molecular and cellular aspects of fibrosis following thermal injury","volume":"16","author":"Scott","year":"2000","journal-title":"Hand Clin"},{"issue":"4","key":"10.1016\/j.pmr.2023.05.002_bib26","doi-asserted-by":"crossref","first-page":"428","DOI":"10.5021\/ad.2013.25.4.428","article-title":"Clinical and histological correlation in post-burn hypertrophic scar for pain and itching sensation","volume":"25","author":"Choi","year":"2013","journal-title":"Ann Dermatol"},{"issue":"2","key":"10.1016\/j.pmr.2023.05.002_bib27","doi-asserted-by":"crossref","first-page":"111","DOI":"10.5999\/aps.2014.41.2.111","article-title":"Analysis of frequency of use of different scar assessment scales based on the scar condition and treatment method","volume":"41","author":"Bae","year":"2014","journal-title":"Arch Plast Surg"},{"issue":"3","key":"10.1016\/j.pmr.2023.05.002_bib28","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.burns.2016.09.008","article-title":"Comparison between high-frequency ultrasonography and histological assessment reveals weak correlation for measurements of scar tissue thickness","volume":"43","author":"Agabalyan","year":"2017","journal-title":"Burns"},{"issue":"6","key":"10.1016\/j.pmr.2023.05.002_bib29","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1016\/j.burns.2017.02.018","article-title":"Evaluating accuracy and reliability of active stereophotogrammetry using MAVIS III Wound Camera for three-dimensional assessment of hypertrophic scars","volume":"43","author":"Su","year":"2017","journal-title":"Burns"},{"issue":"7","key":"10.1016\/j.pmr.2023.05.002_bib30","doi-asserted-by":"crossref","first-page":"1614","DOI":"10.1016\/j.burns.2019.05.005","article-title":"Incorporation of 3D stereophotogrammetry as a reliable method for assessing scar volume in standard clinical practice","volume":"45","author":"Peake","year":"2019","journal-title":"Burns"},{"issue":"3","key":"10.1016\/j.pmr.2023.05.002_bib31","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1097\/BCR.0b013e3181710881","article-title":"Quantitative measurement of hypertrophic scar: interrater reliability and concurrent validity","volume":"29","author":"Nedelec","year":"2008","journal-title":"J\u00a0Burn Care Res"},{"issue":"4","key":"10.1016\/j.pmr.2023.05.002_bib32","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1111\/wrr.12709","article-title":"Patient-reported scar quality of adults after burn injuries: a five-year multicenter follow-up study","volume":"27","author":"Spronk","year":"2019","journal-title":"Wound Repair Regen"},{"issue":"6","key":"10.1016\/j.pmr.2023.05.002_bib33","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1016\/j.burns.2017.03.017","article-title":"Identification of factors predicting scar outcome after burn in adults: a prospective case-control study","volume":"43","author":"Wallace","year":"2017","journal-title":"Burns"},{"key":"10.1016\/j.pmr.2023.05.002_bib34","doi-asserted-by":"crossref","first-page":"88","DOI":"10.3390\/ebj2030008","article-title":"Systematic quantification of hypertrophic scar in adult burn survivors","volume":"2","author":"Edger-Lacoursi\u00e8re","year":"2021","journal-title":"European Burn Journal"},{"issue":"8","key":"10.1016\/j.pmr.2023.05.002_bib35","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.1016\/j.burns.2014.03.002","article-title":"Longitudinal burn scar quantification","volume":"40","author":"Nedelec","year":"2014","journal-title":"Burns"},{"issue":"5","key":"10.1016\/j.pmr.2023.05.002_bib36","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1111\/j.1524-475X.2012.00820.x","article-title":"Outcome after burns: an observational study on burn scar maturation and predictors for severe scarring","volume":"20","author":"van der Wal","year":"2012","journal-title":"Wound Repair Regen"},{"issue":"2","key":"10.1016\/j.pmr.2023.05.002_bib37","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1097\/01.PRS.0000101530.33096.5B","article-title":"The effect of myofibroblast on contracture of hypertrophic scar","volume":"113","author":"Shin","year":"2004","journal-title":"Plast Reconstr Surg"},{"issue":"1","key":"10.1016\/j.pmr.2023.05.002_bib38","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1083\/jcb.122.1.103","article-title":"Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts","volume":"122","author":"Desmouli\u00e8re","year":"1993","journal-title":"J\u00a0Cell Biol"},{"issue":"2","key":"10.1016\/j.pmr.2023.05.002_bib39","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/j.burns.2020.07.018","article-title":"Direct comparison of reproducibility and reliability in quantitative assessments of burn scar properties","volume":"47","author":"Baumann","year":"2021","journal-title":"Burns"},{"issue":"1 Pt 1","key":"10.1016\/j.pmr.2023.05.002_bib40","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1097\/00004630-200021010-00011","article-title":"Assessment with the dermal torque meter of skin pliability after treatment of burns with cultured skin substitutes","volume":"21","author":"Boyce","year":"2000","journal-title":"J\u00a0Burn Care Rehabil"},{"issue":"4","key":"10.1016\/j.pmr.2023.05.002_bib41","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1093\/jbcr\/irx009","article-title":"Burn scar evaluation using the Cutometer\u00ae MPA 580 in comparison to \"Patient and Observer Scar Assessment Scale\" and \"Vancouver Scar Scale\"","volume":"39","author":"Busche","year":"2018","journal-title":"J\u00a0Burn Care Res"},{"issue":"1","key":"10.1016\/j.pmr.2023.05.002_bib42","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1097\/01.bcr.0000194531.93753.c5","article-title":"Tissue tonometry is a simple, objective measure for pliability of burn scar: is it reliable?","volume":"27","author":"Lye","year":"2006","journal-title":"J\u00a0Burn Care Res"},{"issue":"4","key":"10.1016\/j.pmr.2023.05.002_bib43","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1016\/j.burns.2016.10.012","article-title":"Predictive validity of short term scar quality on final burn scar outcome using the Patient and Observer Scar Assessment Scale in patients with minor to moderate burn severity","volume":"43","author":"Goei","year":"2017","journal-title":"Burns"},{"key":"10.1016\/j.pmr.2023.05.002_bib44","doi-asserted-by":"crossref","first-page":"tkab028","DOI":"10.1093\/burnst\/tkab028","article-title":"Longitudinal monitoring and prediction of long-term outcome of scar stiffness on pediatric patients","volume":"9","author":"M\u00fcller","year":"2021","journal-title":"Burns Trauma"},{"issue":"5","key":"10.1016\/j.pmr.2023.05.002_bib45","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1097\/00004630-199709000-00012","article-title":"Postburn dyspigmentation: its assessment, management, and relationship to scarring--a review of the literature","volume":"18","author":"Tyack","year":"1997","journal-title":"J\u00a0Burn Care Rehabil"},{"issue":"3","key":"10.1016\/j.pmr.2023.05.002_bib46","doi-asserted-by":"crossref","first-page":"e187","DOI":"10.1097\/BCR.0b013e318264bf7d","article-title":"Objective color measurements: clinimetric performance of three devices on normal skin and scar tissue","volume":"34","author":"van der Wal","year":"2013","journal-title":"J\u00a0Burn Care Res"},{"issue":"8","key":"10.1016\/j.pmr.2023.05.002_bib47","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1016\/j.burns.2010.03.016","article-title":"Burn scar assessment: a systematic review of objective scar assessment tools","volume":"36","author":"Brusselaers","year":"2010","journal-title":"Burns"},{"issue":"11","key":"10.1016\/j.pmr.2023.05.002_bib48","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21113880","article-title":"Post-burn pruritus","volume":"21","author":"Chung","year":"2020","journal-title":"Int J Mol Sci"},{"issue":"8","key":"10.1016\/j.pmr.2023.05.002_bib49","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.1016\/j.burns.2014.04.004","article-title":"Immunohistochemical analysis of neuropeptides (protein gene product 9.5, substance P and calcitonin gene-related peptide) in hypertrophic burn scar with pain and itching","volume":"40","author":"Kwak","year":"2014","journal-title":"Burns"},{"issue":"3","key":"10.1016\/j.pmr.2023.05.002_bib50","first-page":"156","article-title":"The pruritus severity scale-a novel tool to assess itch in burns patients","volume":"11","author":"Beecher","year":"2021","journal-title":"Int J Burns Trauma"},{"issue":"3","key":"10.1016\/j.pmr.2023.05.002_bib51","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1111\/j.1365-2133.2009.09586.x","article-title":"The 5-D itch scale: a new measure of pruritus","volume":"162","author":"Elman","year":"2010","journal-title":"Br J Dermatol"},{"issue":"3","key":"10.1016\/j.pmr.2023.05.002_bib52","doi-asserted-by":"crossref","first-page":"e47","DOI":"10.1016\/j.burns.2017.02.007","article-title":"Complex regional pain syndrome in burn pathological scarring: a case report and review of the literature","volume":"43","author":"Mewa Kinoo","year":"2017","journal-title":"Burns"},{"issue":"6","key":"10.1016\/j.pmr.2023.05.002_bib53","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1016\/j.burns.2021.08.007","article-title":"Analysis of the predictors of hypertrophic scarring pain and neuropathic pain after burn","volume":"48","author":"Shu","year":"2022","journal-title":"Burns"},{"key":"10.1016\/j.pmr.2023.05.002_bib54","series-title":"Total burn care","first-page":"679","article-title":"Management of pain and other discomforts in burned patients","author":"Meyer","year":"2018"},{"issue":"10052","key":"10.1016\/j.pmr.2023.05.002_bib55","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1016\/S0140-6736(16)31406-4","article-title":"Hypertrophic scarring: the greatest unmet challenge after burn injury","volume":"388","author":"Finnerty","year":"2016","journal-title":"Lancet"},{"issue":"5","key":"10.1016\/j.pmr.2023.05.002_bib56","doi-asserted-by":"crossref","first-page":"1650","DOI":"10.1097\/PRS.0b013e31816a9f6f","article-title":"Maturation of the human scar: an observational study","volume":"121","author":"Bond","year":"2008","journal-title":"Plast Reconstr Surg"},{"issue":"4","key":"10.1016\/j.pmr.2023.05.002_bib57","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1097\/SLA.0000000000001439","article-title":"Genome-wide association study of postburn scarring identifies a novel protective variant","volume":"262","author":"Sood","year":"2015","journal-title":"Ann Surg"},{"issue":"10","key":"10.1016\/j.pmr.2023.05.002_bib58","first-page":"895","article-title":"Hypertrophic burn scars: analysis of variables","volume":"23","author":"Deitch","year":"1983","journal-title":"J\u00a0Trauma"},{"key":"10.1016\/j.pmr.2023.05.002_bib59","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s41038-016-0068-2","article-title":"A\u00a0prospective study of time to healing and hypertrophic scarring in paediatric burns: every day counts","volume":"5","author":"Chipp","year":"2017","journal-title":"Burns Trauma"},{"issue":"1","key":"10.1016\/j.pmr.2023.05.002_bib60","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1097\/BCR.0B013E31802CB860","article-title":"Retrospective study of the association between hypertrophic burn scarring and bacterial colonization","volume":"28","author":"Baker","year":"2007","journal-title":"J\u00a0Burn Care Res"},{"issue":"2","key":"10.1016\/j.pmr.2023.05.002_bib61","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1097\/01.PRS.0000041445.76730.23","article-title":"Effects of burn wound excision on bacterial colonization and invasion","volume":"111","author":"Barret","year":"2003","journal-title":"Plast Reconstr Surg"},{"issue":"3","key":"10.1016\/j.pmr.2023.05.002_bib62","first-page":"97","article-title":"Comparison of healing time of the 2 degree burn wounds with two dressing methods of fundermol herbal ointment and 1% silver sulfadiazine cream","volume":"15","author":"Daryabeigi","year":"2010","journal-title":"Iran J Nurs Midwifery Res"},{"issue":"4","key":"10.1016\/j.pmr.2023.05.002_bib63","first-page":"481","article-title":"Comparison of topical sucralfate and silver sulfadiazine cream in second degree burns in rats","volume":"22","author":"Beheshti","year":"2013","journal-title":"Adv Clin Exp Med"},{"issue":"4","key":"10.1016\/j.pmr.2023.05.002_bib64","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1111\/j.0909-752X.2006.00165.x","article-title":"Mechanobiology and force transduction in scars developed in darker skin types","volume":"12","author":"Quatresooz","year":"2006","journal-title":"Skin Res Technol"},{"issue":"7","key":"10.1016\/j.pmr.2023.05.002_bib65","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1016\/j.burns.2008.01.010","article-title":"Mechanical tension stimulates the transdifferentiation of fibroblasts into myofibroblasts in human burn scars","volume":"34","author":"Junker","year":"2008","journal-title":"Burns"},{"issue":"8","key":"10.1016\/j.pmr.2023.05.002_bib66","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1016\/j.burns.2014.02.005","article-title":"The effect of burn rehabilitation massage therapy on hypertrophic scar after burn: a randomized controlled trial","volume":"40","author":"Cho","year":"2014","journal-title":"Burns"},{"key":"10.1016\/j.pmr.2023.05.002_bib67","series-title":"Total burn care","first-page":"648","article-title":"Laser for burn scar treatment","author":"McLaughlin","year":"2018"},{"issue":"3","key":"10.1016\/j.pmr.2023.05.002_bib68","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1097\/PRS.0000000000001507","article-title":"Burn scar biomechanics after pressure garment therapy","volume":"136","author":"Kim","year":"2015","journal-title":"Plast Reconstr Surg. Sep"},{"issue":"7","key":"10.1016\/j.pmr.2023.05.002_bib69","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1089\/wound.2015.0625","article-title":"The use of silicone adhesives for scar reduction","volume":"4","author":"Bleasdale","year":"2015","journal-title":"Adv Wound Care"},{"issue":"1","key":"10.1016\/j.pmr.2023.05.002_bib70","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.burns.2018.08.018","article-title":"Randomized controlled trial of the immediate and long-term effect of massage on adult postburn scar","volume":"45","author":"Nedelec","year":"2019","journal-title":"Burns"},{"issue":"5","key":"10.1016\/j.pmr.2023.05.002_bib71","doi-asserted-by":"crossref","first-page":"678","DOI":"10.3390\/cells12050678","article-title":"An updated review of hypertrophic scarring","volume":"12","author":"Mony","year":"2023","journal-title":"Cells"},{"key":"10.1016\/j.pmr.2023.05.002_bib72","unstructured":"Sinha S, Gabriel VA, Arora RK, et\u00a0al. Interventions for postburn pruritus. Manuscript submitted for publication."},{"issue":"1","key":"10.1016\/j.pmr.2023.05.002_bib73","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.burns.2018.08.011","article-title":"Comparison of efficacy and safety of intralesional triamcinolone and combination of triamcinolone with 5-fluorouracil in the treatment of keloids and hypertrophic scars: randomised control trial","volume":"45","author":"Khalid","year":"2019","journal-title":"Burns. Feb"},{"issue":"5","key":"10.1016\/j.pmr.2023.05.002_bib74","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1016\/j.burns.2021.02.013","article-title":"The safety and efficacy of intralesional triamcinolone acetonide for keloids and hypertrophic scars: a systematic review and meta-analysis","volume":"47","author":"Zhuang","year":"2021","journal-title":"Burns. Aug"},{"issue":"6","key":"10.1016\/j.pmr.2023.05.002_bib75","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1016\/j.burns.2018.05.005","article-title":"Comparison of intralesional verapamil versus intralesional corticosteroids in treatment of keloids and hypertrophic scars: A randomized controlled trial","volume":"44","author":"Abedini","year":"2018","journal-title":"Burns. Sep"},{"issue":"7","key":"10.1016\/j.pmr.2023.05.002_bib76","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1016\/j.burns.2010.04.014","article-title":"12-Year within-wound study of the effectiveness of custom pressure garment therapy","volume":"36","author":"Engrav","year":"2010","journal-title":"Burns. Nov"},{"issue":"3","key":"10.1016\/j.pmr.2023.05.002_bib77","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1016\/j.burns.2015.12.006","article-title":"The effects of conservative treatments on burn scars: a systematic review","volume":"42","author":"Anthonissen","year":"2016","journal-title":"Burns. May"},{"issue":"3","key":"10.1016\/j.pmr.2023.05.002_bib78","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1097\/BCR.0000000000000124","article-title":"Practice guidelines for the application of nonsilicone or silicone gels and gel sheets after burn injury","volume":"36","author":"Nedelec","year":"2015","journal-title":"J\u00a0Burn Care Res"},{"issue":"2","key":"10.1016\/j.pmr.2023.05.002_bib79","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1002\/lsm.23201","article-title":"Laser treatment of traumatic scars and contractures: 2020 international consensus recommendations","volume":"52","author":"Seago","year":"2020","journal-title":"Lasers Surg Med. Feb"}],"container-title":["Physical Medicine and Rehabilitation Clinics of North America"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1047965123000347?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1047965123000347?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T03:44:27Z","timestamp":1760931867000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1047965123000347"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11]]},"references-count":79,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,11]]}},"alternative-id":["S1047965123000347"],"URL":"https:\/\/doi.org\/10.1016\/j.pmr.2023.05.002","relation":{},"ISSN":["1047-9651"],"issn-type":[{"value":"1047-9651","type":"print"}],"subject":[],"published":{"date-parts":[[2023,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hypertrophic Scar","name":"articletitle","label":"Article Title"},{"value":"Physical Medicine and Rehabilitation Clinics of North America","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pmr.2023.05.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}