{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T06:49:09Z","timestamp":1788504549359,"version":"build-2803163510"},"reference-count":20,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2011,5,11]],"date-time":"2011-05-11T00:00:00Z","timestamp":1305072000000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["PM&amp;R"],"published-print":{"date-parts":[[2011,5]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To investigate whether intermittent catheterization (IC) with a hydrophilic\u2010coated catheter delays the onset of the first symptomatic urinary tract infection (UTI) and reduces the number of symptomatic UTIs in patients with acute spinal cord injury (SCI) compared with IC with standard, uncoated catheters.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>A prospective, randomized, parallel\u2010group trial.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Fifteen North American SCI centers. Participants were followed up while in the hospital or rehabilitation unit (institutional period) and up to 3 months after institutional discharge (community period). The maximal study period was 6 months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>A total of 224 subjects with traumatic SCI of less than 3 months' duration who use IC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The participants were randomized within 10 days of starting IC to either single\u2010use hydrophilic\u2010coated (SpeediCath) or polyvinyl chloride uncoated (Conveen) catheters.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main Outcome Measurements<\/jats:title><jats:p>The time from the first catheterization to the first antibiotic\u2010treated symptomatic UTI was measured as well as the total number of symptomatic UTIs during the study period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The time to the first antibiotic\u2010treated symptomatic UTI was significantly delayed in the hydrophilic\u2010coated catheter group compared with the uncoated catheter group. The delay corresponded to a 33% decrease in the daily risk of developing the first symptomatic UTI among participants who used the hydrophilic\u2010coated catheter. In the institutional period, the incidence of antibiotic\u2010treated symptomatic UTIs was reduced by 21% (<jats:italic>P<\/jats:italic> &lt; .05) in the hydrophilic\u2010coated catheter group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The use of a hydrophilic\u2010coated catheter for IC is associated with a delay in the onset of the first antibiotic\u2010treated symptomatic UTI and with a reduction in the incidence of symptomatic UTI in patients with acute SCI during the acute inpatient rehabilitation. Using a hydrophilic\u2010coated catheter could minimize UTI\u2010related complications, treatment costs, and rehabilitation delays in this group of patients, and reduce the emergence of antibiotic\u2010resistant organisms.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.pmrj.2011.01.001","type":"journal-article","created":{"date-parts":[[2011,5,20]],"date-time":"2011-05-20T23:07:17Z","timestamp":1305932837000},"page":"408-417","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":111,"title":["Intermittent Catheterization With a Hydrophilic\u2010Coated Catheter Delays Urinary Tract Infections in Acute Spinal Cord Injury: A Prospective, Randomized, Multicenter Trial"],"prefix":"10.1002","volume":"3","author":[{"given":"Diana D.","family":"Cardenas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine 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