{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T21:16:45Z","timestamp":1761513405600},"reference-count":13,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2014,1,15]],"date-time":"2014-01-15T00:00:00Z","timestamp":1389744000000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["PM&amp;R"],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:sec><jats:label \/><jats:p>Juvenile rheumatoid arthritis (JRA) is the most common rheumatologic disease in children. Moreover, multiple sclerosis (MS) is the most frequent demyelinating disease and has been associated with various chronic inflammatory diseases. However, its association with JRA has not been frequently described. Autoimmunity in both JRA and MS has been documented in the scientific literature, although there has been no definitive finding that patients with JRA are prone to the development of MS. An increasing frequency of MS resulting from an increased use of antitumor necrosis factor agents in the treatment of rheumatoid arthritis and other chronic inflammatory diseases has been reported recently. In this study, we report on the development of MS in a patient with JRA who did not have a history of antitumor necrosis factor use.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.pmrj.2013.08.608","type":"journal-article","created":{"date-parts":[[2014,1,15]],"date-time":"2014-01-15T14:22:21Z","timestamp":1389795741000},"page":"96-99","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Dual Diagnosis: Rheumatoid Arthritis and Multiple Sclerosis"],"prefix":"10.1002","volume":"6","author":[{"given":"Mustafa","family":"Ozsahin","sequence":"first","affiliation":[{"name":"Medical School of Duzce University Department of Physical Medicine and Rehabilitation Duzce Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suber","family":"Dikici","sequence":"additional","affiliation":[{"name":"Department of Neurology Medical School of Duzce University Duzce Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00fclsen","family":"Kocaman","sequence":"additional","affiliation":[{"name":"Department of Neurology Bezmi Alem Vakif University Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fahri Halit","family":"Besir","sequence":"additional","affiliation":[{"name":"Department of Radiology Medical School of Duzce University Duzce Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Davut","family":"Baltaci","sequence":"additional","affiliation":[{"name":"Department of Family Medicine Medical School of Duzce University Duzce Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Safinaz","family":"Ataoglu","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation Medical School of Duzce University Duzce Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,1,15]]},"reference":[{"key":"e_1_2_5_2_2","first-page":"85","article-title":"Coincidence of juvenile idiopathic arthritis and multiple sclerosis: Case report","volume":"52","author":"Puszczewicz M.J.","year":"2006","journal-title":"Ann Acad Med Stetin"},{"key":"e_1_2_5_3_2","first-page":"162857","article-title":"Concurrence of juvenile idiopathic arthritis and multiple sclerosis","volume":"2011","author":"Kaouther B.A.","year":"2011","journal-title":"Case Rep Rheumatol"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.1032"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.61.10.1613"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.10370"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780400822"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2003.014886"},{"key":"e_1_2_5_9_2","first-page":"1027","article-title":"Association of rheumatoid arthritis with multiple sclerosis: Report of 14 cases and discussion of its significance","volume":"33","author":"Toussirot E.","year":"2006","journal-title":"J Rheumatol"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2003.016410"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.1996.tb00004.x"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1177\/1352458510369146"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(200109)44:9<1977::AID-ART345>3.0.CO;2-6"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(200112)44:12<2862::AID-ART474>3.0.CO;2-W"}],"container-title":["PM&amp;R"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1016%2Fj.pmrj.2013.08.608","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1934148213010733?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1934148213010733?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.pmrj.2013.08.608","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,3]],"date-time":"2023-11-03T11:23:53Z","timestamp":1699010633000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1016\/j.pmrj.2013.08.608"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,1]]}},"alternative-id":["10.1016\/j.pmrj.2013.08.608"],"URL":"https:\/\/doi.org\/10.1016\/j.pmrj.2013.08.608","archive":["Portico"],"relation":{},"ISSN":["1934-1482","1934-1563"],"issn-type":[{"value":"1934-1482","type":"print"},{"value":"1934-1563","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,1]]},"assertion":[{"value":"2013-02-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-08-23","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-01-15","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}