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Self\u2010reported physical activity was not significantly different between patients and controls (<jats:italic>P<\/jats:italic> = .99), but levels of moderate and vigorous physical activity as measured by actigraphy were significantly lower in patients (<jats:italic>P<\/jats:italic> = .012 and <jats:italic>P<\/jats:italic> = .047, respectively). Exercise capacity (6\u2010Minute Walk) was poorer in patients (<jats:italic>P<\/jats:italic> = .0006), but there was no significant difference in maximal volume of oxygen consumption (<jats:italic>P<\/jats:italic> = .07).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Patients with fibromyalgia report more severe symptoms across all domains, including physical activity and autonomic symptoms, compared with controls, but the objective assessments only showed modest differences. Our results suggest that patients with widespread subjective impairment of function have only modest objective measures of autonomic dysfunction. We recommend that the primary treatment goal should be focused on restoration of function, which may also ameliorate symptoms.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.pmrj.2015.08.008","type":"journal-article","created":{"date-parts":[[2015,8,24]],"date-time":"2015-08-24T08:40:02Z","timestamp":1440405602000},"page":"425-435","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":39,"title":["Patients With Fibromyalgia Have Significant Autonomic Symptoms But Modest Autonomic Dysfunction"],"prefix":"10.1002","volume":"8","author":[{"given":"Ann","family":"Vincent","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary O.","family":"Whipple","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phillip 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