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This is a report of sudden onset, pure hand weakness, without any other neurological signs or symptoms in the setting of a prolonged hospital stay for bilateral diabetic foot ulceration. A cerebral magnetic resonance image identified an \u201cinverted omega sign\u201d along the right precentral gyrus and paracentral lobule, consistent with an area of acute cortical infarction. Patients with acute pure hand weakness, and risk factors for cerebral vascular disease, should be carefully evaluated for a cortical lesion in addition to the routine peripheral neurologic workup.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.pmrj.2016.10.024","type":"journal-article","created":{"date-parts":[[2016,11,11]],"date-time":"2016-11-11T02:47:59Z","timestamp":1478832479000},"page":"419-421","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Isolated Unilateral Hand Weakness Due to Cortical Cerebral Ischemia"],"prefix":"10.1002","volume":"9","author":[{"given":"Wei","family":"Qu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew","family":"Gardiner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,11,11]]},"reference":[{"key":"e_1_2_4_2_2","first-page":"429","article-title":"Hand monoparesis due to small cortical ischemic stroke, etiology, prognosis and medical management: Case report and literature review","volume":"4","author":"Eboli P.","year":"2013","journal-title":"J Med Cases"},{"key":"e_1_2_4_3_2","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1093\/ageing\/afp025","article-title":"Pseudoperipheral palsy due to cortical infarction","volume":"38","author":"Rankin E.M.","year":"2009","journal-title":"Age Ageing"},{"key":"e_1_2_4_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/NRL.0b013e31814db093"},{"key":"e_1_2_4_5_2","first-page":"10","article-title":"Pure motor upper limb weakness and infarction in the precentral gyrus: Mechanisms of stroke","volume":"4","author":"Pikula A.","year":"2011","journal-title":"J Vasc Interv Neurol"},{"key":"e_1_2_4_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0929-6646(09)60276-X"},{"key":"e_1_2_4_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/NRL.0b013e318220c690"},{"key":"e_1_2_4_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.62.8.1221"},{"key":"e_1_2_4_9_2","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1007\/s00415-009-5104-8","article-title":"Ischemic stroke of the cortical \u201chand knob\u201d area: Stroke mechanisms and prognosis","volume":"256","author":"Peters N.","year":"2009","journal-title":"J Neurol"}],"container-title":["PM&amp;R"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1016%2Fj.pmrj.2016.10.024","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1934148216311236?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1934148216311236?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.pmrj.2016.10.024","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T17:05:45Z","timestamp":1694711145000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1016\/j.pmrj.2016.10.024"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11,11]]},"references-count":8,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,4]]}},"alternative-id":["10.1016\/j.pmrj.2016.10.024"],"URL":"https:\/\/doi.org\/10.1016\/j.pmrj.2016.10.024","archive":["Portico"],"relation":{},"ISSN":["1934-1482","1934-1563"],"issn-type":[{"value":"1934-1482","type":"print"},{"value":"1934-1563","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,11,11]]},"assertion":[{"value":"2015-12-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-10-27","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-11-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}