{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T22:24:45Z","timestamp":1788819885786,"version":"build-2803163510"},"reference-count":30,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,2,13]],"date-time":"2019-02-13T00:00:00Z","timestamp":1550016000000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["PM&amp;R"],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The relation between chronic musculoskeletal pain and joint hypermobility in a small percentage of the pediatric population is well described. However, literature discussing the treatment of chronic pain associated with joint hypermobility in pediatrics is limited. The present study examines the impact of interdisciplinary treatment on chronic pain in pediatrics with joint hypermobility syndrome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To determine if pediatric patients with chronic pain related to joint hypermobility can be effectively treated with an intensive, interdisciplinary pain management program, as measured by changes in pain, psychosocial and physical functioning, as well as parental coping.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Retrospective cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Urban academic tertiary intensive outpatient interdisciplinary pain management clinic.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>The study involved 30 patients who met the criteria for a diagnosis of joint hypermobility and chronic pain and completed an interdisciplinary pain management program.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Intervention<\/jats:title>\n                    <jats:p>All patients were treated in an intensive pediatric interdisciplinary pain management program for a duration of 6 to 8\u2009weeks. The program provided physical therapy, occupational therapy, psychological counseling, and weekly pediatric rehabilitation medicine follow\u2010up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcome Measures<\/jats:title>\n                    <jats:p>\n                      Outcome measures included numeric rating scale pain scores, the Bath Adolescent Pain Questionnaire, and the Bath Adolescent Pain\u2010Parent Impact Questionnaire. Changes from pre\u2010 to post\u2010treatment were analyzed using paired\u2010samples\n                      <jats:italic>t<\/jats:italic>\n                      tests.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Patients endorsed pre\u2010 to post\u2010treatment improvements in pain, depression, general anxiety, pain\u2010related anxiety, social functioning, and physical functioning (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u2009.05). The patients' parents showed significant improvements in depression, anxiety, catastrophic thinking, self\u2010blame and helplessness, leisure functioning, and parental behavior (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u2009.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The present findings suggest that an intensive interdisciplinary rehabilitation pain management program yields short\u2010term improvements in pain, emotional and physical function, and daily activity in a pediatric population diagnosed with joint hypermobility. Parents also experienced benefits from the program. A larger prospective study with longer\u2010term follow\u2010up is needed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>III<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.pmrj.2018.06.018","type":"journal-article","created":{"date-parts":[[2018,7,30]],"date-time":"2018-07-30T22:01:30Z","timestamp":1532988090000},"page":"150-157","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Interdisciplinary Pain Management Improves Pain and Function in Pediatric Patients with Chronic Pain Associated with Joint Hypermobility Syndrome"],"prefix":"10.1002","volume":"11","author":[{"given":"Gadi","family":"Revivo","sequence":"first","affiliation":[{"name":"Pain Management Center, Shirley Ryan Abilitylab  Chicago IL"},{"name":"Pain Management Center, Department of Physical Medicine and Rehabilitation, McGaw Medical Center Northwestern University Feinberg School of Medicine  Chicago Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diane K.","family":"Amstutz","sequence":"additional","affiliation":[{"name":"Pain Management Center Shirley Ryan Abilitylab  Chicago IL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine M.","family":"Gagnon","sequence":"additional","affiliation":[{"name":"Pain Management Center, Shirley Ryan Abilitylab  Chicago IL"},{"name":"Department of Physical Medicine and Rehabilitation, McGaw Medical Center Northwestern University Feinberg School of Medicine  Chicago Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zachary L.","family":"McCormick","sequence":"additional","affiliation":[{"name":"Physical Medicine and Rehabilitation, Department of Orthopaedic Surgery University of California  San Francisco California"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,2,13]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12969-015-0039-3"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kep362"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-9406(05)61005-X"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2005-2219"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keh557"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2005.12.003"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.33070"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.c.31552"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.c.31539"},{"key":"e_1_2_7_11_1","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1136\/adc.66.8.931","article-title":"Prognosis of motor development and joint hypermobility","volume":"66","author":"Triosh E","year":"1991","journal-title":"Arch Dis Child"},{"key":"e_1_2_7_12_1","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1097\/01.pep.0000186505.32548.84","article-title":"The relationship between generalized joint hypermobility and motor development","volume":"12","author":"Engelbert RH","year":"2005","journal-title":"Pediatr Phys Ther"},{"key":"e_1_2_7_13_1","first-page":"1777","article-title":"The revised (Brighton 1998) criteria for the diagnosis of benign joint hypermobility syndrome (BJHS)","volume":"27","author":"Grahame R","year":"2000","journal-title":"J Rheumatol"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2010.07.021"},{"key":"e_1_2_7_15_1","first-page":"798","article-title":"Are diagnostic criteria for general joint hypermobility and benign joint hypermobility syndrome based on reproducible and valid tests? 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