{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T09:34:51Z","timestamp":1791279291089,"version":"4.1.0"},"reference-count":50,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2008,12,1]],"date-time":"2008-12-01T00:00:00Z","timestamp":1228089600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,12,1]],"date-time":"2008-12-01T00:00:00Z","timestamp":1228089600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Revue de Pneumologie Clinique"],"published-print":{"date-parts":[[2008,12]]},"DOI":"10.1016\/j.pneumo.2008.09.004","type":"journal-article","created":{"date-parts":[[2008,11,18]],"date-time":"2008-11-18T07:06:18Z","timestamp":1226991978000},"page":"282-289","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Maladie veineuse thromboembolique et cancer"],"prefix":"10.1016","volume":"64","author":[{"given":"R.","family":"Descourt","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Jezequel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Couturaud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Leroyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Girard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.pneumo.2008.09.004_bib1","unstructured":"Dieulafoy G. Cancer de l\u2019estomac. Manuel de pathologie interne. Tome 2. 1861."},{"key":"10.1016\/j.pneumo.2008.09.004_bib2","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1177\/1073274805012003S02","article-title":"Cancer and venous thromboembolism: scope of the problem","volume":"12","author":"Heit","year":"2005","journal-title":"Cancer Control"},{"key":"10.1016\/j.pneumo.2008.09.004_bib3","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1056\/NEJMp030086","article-title":"Cancer-associated thrombosis","volume":"349","author":"Bick","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pneumo.2008.09.004_bib4","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/S0305-7372(02)00044-0","article-title":"Cancer and thromboembolic disease: pathogenic mechanisms","volume":"28","author":"Lee","year":"2002","journal-title":"Cancer Treat Rev"},{"key":"10.1016\/j.pneumo.2008.09.004_bib5","doi-asserted-by":"crossref","unstructured":"Khorana AA. Increasing risk for venous thromboembolism among hospitalized cancer patients. J Clin Oncol 2007; ASCO Annual Meeting Proceedings. Part I. 25.","DOI":"10.1200\/jco.2007.25.18_suppl.9009"},{"key":"10.1016\/j.pneumo.2008.09.004_bib6","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1001\/archinte.160.6.809","article-title":"Risk factors for deep vein thrombosis and pulmonary embolism: a population-based case-control study","volume":"160","author":"Heit","year":"2000","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.pneumo.2008.09.004_bib7","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1001\/jama.293.6.715","article-title":"Malignancies, prothrombotic mutations, and the risk of venous thrombosis","volume":"293","author":"Blom","year":"2005","journal-title":"JAMA"},{"key":"10.1016\/j.pneumo.2008.09.004_bib8","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1001\/archinte.160.6.761","article-title":"Predictors of recurrence after deep vein thrombosis and pulmonary embolism: a population-based cohort study","volume":"160","author":"Heit","year":"2000","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.pneumo.2008.09.004_bib9","doi-asserted-by":"crossref","first-page":"3484","DOI":"10.1182\/blood-2002-01-0108","article-title":"Recurrent venous thromboembolism and bleeding complications during anticoagulant treatment in patients with cancer and venous thrombosis","volume":"100","author":"Prandoni","year":"2002","journal-title":"Blood"},{"key":"10.1016\/j.pneumo.2008.09.004_bib10","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1160\/TH06-01-0009","article-title":"Recurrent venous thromboembolism under anticoagulant therapy: a high risk in adenocarcinoma?","volume":"95","author":"Descourt","year":"2006","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.pneumo.2008.09.004_bib11","doi-asserted-by":"crossref","first-page":"1846","DOI":"10.1056\/NEJM200012213432504","article-title":"Prognosis of cancers associated with venous thromboembolism","volume":"343","author":"Sorensen","year":"2000","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pneumo.2008.09.004_bib12","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1001\/archinte.166.4.458","article-title":"Incidence of venous thromboembolism and its effect on survival among patients with common cancers","volume":"166","author":"Chew","year":"2006","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.pneumo.2008.09.004_bib13","doi-asserted-by":"crossref","first-page":"2731","DOI":"10.1200\/JCO.1996.14.10.2731","article-title":"Increased thromboembolic complications with concurrent tamoxifen and chemotherapy in a randomized trial of adjuvant therapy for women with breast cancer. National Cancer Institute of Canada Clinical Trials Group Breast Cancer Site Group","volume":"14","author":"Pritchard","year":"1996","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.pneumo.2008.09.004_bib14","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/j.ygyno.2004.10.023","article-title":"Thromboembolic events in patients treated with definitive chemotherapy and radiation therapy for invasive cervical cancer","volume":"96","author":"Jacobson","year":"2005","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.pneumo.2008.09.004_bib15","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1002\/cncr.20893","article-title":"Prospective evaluation of major vascular events in patients with nonsmall cell lung carcinoma treated with cisplatin and gemcitabine","volume":"103","author":"Numico","year":"2005","journal-title":"Cancer"},{"key":"10.1016\/j.pneumo.2008.09.004_bib16","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1634\/theoncologist.9-suppl_1-43","article-title":"Bevacizumab in the treatment of breast cancer: rationale and current data","volume":"9","author":"Rugo","year":"2004","journal-title":"Oncologist"},{"key":"10.1016\/j.pneumo.2008.09.004_bib17","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1634\/theoncologist.9-suppl_1-19","article-title":"Non-small cell lung cancer and antiangiogenic therapy: what can be expected of bevacizumab?","volume":"9","author":"Herbst","year":"2004","journal-title":"Oncologist"},{"key":"10.1016\/j.pneumo.2008.09.004_bib18","doi-asserted-by":"crossref","first-page":"5490","DOI":"10.1200\/JCO.2007.14.1283","article-title":"American Society of Clinical Oncology guideline: recommendations for venous thromboembolism prophylaxis and treatment in patients with cancer","volume":"25","author":"Lyman","year":"2007","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.pneumo.2008.09.004_bib19","unstructured":"Luksenburg H et al. (2004) FDA oncologic drugs advisory committee briefing document: safety concerns associated with Aranesp (darbepotin alfa) Amgen, Inc. and Procrit (epoetin alfa) Ortho Biotech, L.P., for the treatment of anemia associated with cancer chemotherapy, FDA. [http:\/\/www.fda.gov:ohrms\/dockets\/ac\/04\/briefing\/4037b2.htm] (accessed 22 June 2005)."},{"key":"10.1016\/j.pneumo.2008.09.004_bib20","doi-asserted-by":"crossref","first-page":"1514","DOI":"10.1002\/cncr.11700","article-title":"Increased incidence of symptomatic venous thrombosis in patients with cervical carcinoma treated with concurrent chemotherapy, radiation, and erythropoietin","volume":"98","author":"Wun","year":"2003","journal-title":"Cancer"},{"key":"10.1016\/j.pneumo.2008.09.004_bib21","doi-asserted-by":"crossref","first-page":"338S","DOI":"10.1378\/chest.126.3_suppl.338S","article-title":"Prevention of venous thromboembolism: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy","volume":"126","author":"Geerts","year":"2004","journal-title":"Chest"},{"key":"10.1016\/j.pneumo.2008.09.004_bib22","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1160\/TH03-03-0152","article-title":"Incidence of symptomatic venous thromboembolism after different elective or urgent surgical procedures","volume":"90","author":"White","year":"2003","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.pneumo.2008.09.004_bib23","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1056\/NEJMoa012385","article-title":"Duration of prophylaxis against venous thromboembolism with enoxaparin after surgery for cancer","volume":"346","author":"Bergqvist","year":"2002","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pneumo.2008.09.004_bib24","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1055\/s-2007-994916","article-title":"Thrombotic complications of central venous catheters in cancer patients","volume":"25","author":"Bona","year":"1999","journal-title":"Semin Thromb Hemost"},{"key":"10.1016\/j.pneumo.2008.09.004_bib25","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.revmed.2005.11.016","article-title":"Venous thromboembolism and cancer","volume":"27","author":"Pavic","year":"2006","journal-title":"Rev Med Interne"},{"key":"10.1016\/j.pneumo.2008.09.004_bib26","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1160\/TH05-12-0791","article-title":"Clinical usefulness of D-dimer testing in cancer patients with suspected pulmonary embolism","volume":"95","author":"Righini","year":"2006","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.pneumo.2008.09.004_bib27","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.critrevonc.2006.05.001","article-title":"Venous thromboembolism and cancer: guidelines of the Italian Association of Medical Oncology (AIOM)","volume":"59","author":"Mandala","year":"2006","journal-title":"Crit Rev Oncol Hematol"},{"key":"10.1016\/j.pneumo.2008.09.004_bib28","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1056\/NEJMoa025313","article-title":"Low-molecular-weight heparin versus a coumarin for the prevention of recurrent venous thromboembolism in patients with cancer","volume":"349","author":"Lee","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pneumo.2008.09.004_bib29","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1001\/archinte.162.15.1729","article-title":"Comparison of low-molecular-weight heparin and warfarin for the secondary prevention of venous thromboembolism in patients with cancer: a randomized controlled study","volume":"162","author":"Meyer","year":"2002","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.pneumo.2008.09.004_bib30","doi-asserted-by":"crossref","first-page":"S58","DOI":"10.3747\/co.2008.177","article-title":"Cancer-associated thrombosis: prevention and treatment","volume":"15","author":"Brose","year":"2008","journal-title":"Curr Oncol"},{"key":"10.1016\/j.pneumo.2008.09.004_bib31","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1634\/theoncologist.12-11-1361","article-title":"The NCCN Clinical Practice Guidelines on Venous Thromboembolic Disease: strategies for improving VTE prophylaxis in hospitalized cancer patients","volume":"12","author":"Khorana","year":"2007","journal-title":"Oncologist"},{"key":"10.1016\/j.pneumo.2008.09.004_bib32","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0037-1963(01)90096-4","article-title":"Benefits of deep-vein thrombosis prophylaxis in the nonsurgical patient: The MEDENOX trial","volume":"38","author":"Cohen","year":"2001","journal-title":"Semin Hematol"},{"key":"10.1016\/j.pneumo.2008.09.004_bib33","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1177\/1358863X07079017","article-title":"Thromboprophylaxis with dalteparin in medical patients: which patients benefit?","volume":"12","author":"Cohen","year":"2007","journal-title":"Vasc Med"},{"key":"10.1016\/j.pneumo.2008.09.004_bib34","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1136\/bmj.38733.466748.7C","article-title":"Efficacy and safety of fondaparinux for the prevention of venous thromboembolism in older acute medical patients: randomised placebo controlled trial","volume":"332","author":"Cohen","year":"2006","journal-title":"BMJ"},{"key":"10.1016\/j.pneumo.2008.09.004_bib35","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1056\/NEJM199210153271604","article-title":"Deep-vein thrombosis and the incidence of subsequent symptomatic cancer","volume":"327","author":"Prandoni","year":"1992","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pneumo.2008.09.004_bib36","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1002\/(SICI)1097-0142(19980701)83:1<180::AID-CNCR24>3.0.CO;2-S","article-title":"Undiagnosed malignancy in patients with deep vein thrombosis: incidence, risk indicators, and diagnosis","volume":"83","author":"Hettiarachchi","year":"1998","journal-title":"Cancer"},{"key":"10.1016\/j.pneumo.2008.09.004_bib37","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1055\/s-0038-1657740","article-title":"Occult cancer in patients with venous thromboembolism: which patients,which cancers","volume":"78","author":"Monreal","year":"1997","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.pneumo.2008.09.004_bib38","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1056\/NEJM199804233381701","article-title":"The risk of a diagnosis of cancer after primary deep venous thrombosis or pulmonary embolism","volume":"338","author":"Sorensen","year":"1998","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pneumo.2008.09.004_bib39","doi-asserted-by":"crossref","first-page":"1782","DOI":"10.1001\/archinte.165.15.1782","article-title":"Incidence of venous thromboembolism in the year before the diagnosis of cancer in 528,693 adults","volume":"165","author":"White","year":"2005","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.pneumo.2008.09.004_bib40","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1016\/S0140-6736(97)10018-6","article-title":"Venous thromboembolism and cancer","volume":"351","author":"Baron","year":"1998","journal-title":"Lancet"},{"key":"10.1016\/j.pneumo.2008.09.004_bib41","doi-asserted-by":"crossref","first-page":"V187","DOI":"10.1016\/S0049-3848(01)00235-3","article-title":"Venous thromboembolism and occult malignancy","volume":"102","author":"Otten","year":"2001","journal-title":"Thromb Res"},{"key":"10.1016\/j.pneumo.2008.09.004_bib42","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1097\/00001721-199912000-00001","article-title":"Venous thromboses of upper limbs are more frequently associated with occult cancer as compared with those of lower limbs","volume":"10","author":"Girolami","year":"1999","journal-title":"Blood Coag Fibrinol"},{"key":"10.1016\/j.pneumo.2008.09.004_bib43","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1111\/j.1538-7836.2005.01393.x","article-title":"Site and clinical outcome of deep vein thrombosis of the lower limbs: an epidemiological study","volume":"3","author":"Seinturier","year":"2005","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.pneumo.2008.09.004_bib44","article-title":"The location of deep-vein thrombosis as a predictive factor for recurrence and cancer discovery after proximal deep-vein thrombosis","volume":"88","author":"Laporte","year":"2003","journal-title":"Haematologica"},{"key":"10.1016\/j.pneumo.2008.09.004_bib45","doi-asserted-by":"crossref","first-page":"3078","DOI":"10.1200\/JCO.2000.18.17.3078","article-title":"Incidence of recurrent thromboembolic and bleeding complications among patients with venous thromboembolism in relation to both malignancy and achieved internationalised ratio: a retrospective analysis","volume":"18","author":"Hutten","year":"2000","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.pneumo.2008.09.004_bib46","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1111\/j.1538-7836.2008.02837.x","article-title":"Clinical outcome in patients with venous thromboembolism and hidden cancer: findings from the RIETE Registry","volume":"6","author":"Trujillo-Santos","year":"2008","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.pneumo.2008.09.004_bib47","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1111\/j.1538-7836.2004.00721.x","article-title":"Screening for occult cancer in patients with acute deep vein thrombosis or pulmonary embolism","volume":"2","author":"Monreal","year":"2004","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.pneumo.2008.09.004_bib48","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1111\/j.1538-7836.2004.00720.x","article-title":"Extensive screening for occult malignant disease in idiopathic venous thromboembolism: a prospective randomized clinical trial","volume":"2","author":"Piccioli","year":"2004","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.pneumo.2008.09.004_bib49","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1097\/00005792-199909000-00001","article-title":"Rates of initial and recurrent thromboembolic disease among patients with malignancy versus those without malignancy. Risk analysis using Medicare claims data","volume":"78","author":"Levitan","year":"1999","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.pneumo.2008.09.004_bib50","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1055\/s-0037-1613136","article-title":"Variation in relative risk of venous thromboembolism in different cancers","volume":"87","author":"Thodiyil","year":"2002","journal-title":"Thromb Haemost"}],"container-title":["Revue de Pneumologie Clinique"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0761841708001259?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0761841708001259?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T14:12:26Z","timestamp":1760105546000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0761841708001259"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,12]]},"references-count":50,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2008,12]]}},"alternative-id":["S0761841708001259"],"URL":"https:\/\/doi.org\/10.1016\/j.pneumo.2008.09.004","relation":{},"ISSN":["0761-8417"],"issn-type":[{"value":"0761-8417","type":"print"}],"subject":[],"published":{"date-parts":[[2008,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Maladie veineuse thromboembolique et cancer","name":"articletitle","label":"Article Title"},{"value":"Revue de Pneumologie Clinique","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pneumo.2008.09.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2008 Published by Elsevier Masson SAS","name":"copyright","label":"Copyright"}]}}