{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T00:55:04Z","timestamp":1788828904289,"version":"build-2803163510"},"reference-count":79,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2007,5,1]],"date-time":"2007-05-01T00:00:00Z","timestamp":1177977600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Progress in Neurobiology"],"published-print":{"date-parts":[[2007,5]]},"DOI":"10.1016\/j.pneurobio.2007.02.002","type":"journal-article","created":{"date-parts":[[2007,2,16]],"date-time":"2007-02-16T07:21:47Z","timestamp":1171610507000},"page":"1-10","source":"Crossref","is-referenced-by-count":104,"title":["Biological effects of toosendanin, a triterpenoid extracted from Chinese traditional medicine"],"prefix":"10.1016","volume":"82","author":[{"given":"Yu-Liang","family":"Shi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mu-Feng","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.pneurobio.2007.02.002_bib1","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1001\/jama.280.18.1585","article-title":"Treatment of irritable bowel syndrome with Chinese herbal medicine: a randomized controlled trial","volume":"280","author":"Bensoussan","year":"1998","journal-title":"JAMA"},{"key":"10.1016\/j.pneurobio.2007.02.002_bib2","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/0014-5793(87)80562-8","article-title":"The N-terminal half of the heavy chain of botulinum type A neurotoxin forms channels in planar phospholipid bilayers","volume":"226","author":"Blaustein","year":"1987","journal-title":"FEBS Lett."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib3","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1021\/jf025811w","article-title":"Antifeedant and insecticide properties of a limonoid from Melia azedarach (Meliaceae) with potential use for pest management","volume":"51","author":"Carpinella","year":"2003","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib4","first-page":"1","article-title":"The morphological changes induced by toosendanin on NG108-15 cells and SK-N-SH cells","volume":"23","author":"Chen","year":"2000","journal-title":"Chin. J. Anat."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib5","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1007\/BF02886136","article-title":"Toosendanin-induced change of dopamine level detected by microdialysis in vivo at rat striatum","volume":"44","author":"Chen","year":"1999","journal-title":"Chin. Sci. Bull."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib6","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1177\/00912700022009198","article-title":"Review: drug therapy in Chinese traditional medicine","volume":"40","author":"Cheng","year":"2000","journal-title":"J. Clin. Pharmacol."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib7","first-page":"69","article-title":"Recent advances in research on botanical insecticides in China","volume":"vol. 387","author":"Chiu","year":"1989"},{"key":"10.1016\/j.pneurobio.2007.02.002_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1083\/jcb.52.1.1","article-title":"Changes in the fine structure of neuromuscular junction of the frog caused by black widow spider venom","volume":"52","author":"Clark","year":"1972","journal-title":"J. Cell. Biol."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib9","doi-asserted-by":"crossref","first-page":"918","DOI":"10.3748\/wjg.v8.i5.918","article-title":"The pre-synaptic blocker toosendanin does not inhibit secretion in exocrine cells","volume":"8","author":"Cui","year":"2002","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib10","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/S0168-0102(01)00283-8","article-title":"Different actions of toosendanin on perineurially recorded Ca2+ currents in mouse and frog motor nerve terminals","volume":"41","author":"Ding","year":"2001","journal-title":"Neurosci. Res."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib11","doi-asserted-by":"crossref","first-page":"2872","DOI":"10.1021\/bi00358a020","article-title":"Ion-conducting channels produced by botulinum toxin in planar lipid membranes","volume":"25","author":"Donovan","year":"1986","journal-title":"Biochemistry"},{"key":"10.1016\/j.pneurobio.2007.02.002_bib12","first-page":"147","article-title":"Effects of toosendanin on electric and mechanical properties of guinea pig papillary muscles","volume":"15","author":"Gao","year":"1994","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib13","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1002\/stem.5530120110","article-title":"Highlight on the studies of anticancer drugs derived from plants in China","volume":"12","author":"Han","year":"1994","journal-title":"Stem Cells"},{"key":"10.1016\/j.pneurobio.2007.02.002_bib14","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/S0006-291X(03)00616-8","article-title":"Calcium signaling and apoptosis","volume":"304","author":"Hajnoczky","year":"2003","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib15","doi-asserted-by":"crossref","first-page":"1692","DOI":"10.1073\/pnas.82.6.1692","article-title":"Channels formed by botulinum, tetanus, and diphtheria toxins in planar lipid bilayers: relevance to translocation of proteins across membranes","volume":"82","author":"Hoch","year":"1985","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib16","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/S0006-8993(96)01389-3","article-title":"Inhibition of toosendanin on the delayed rectifier potassium current in neuroblastoma\u00d7glioma NG108-15 cells","volume":"751","author":"Hu","year":"1997","journal-title":"Brain Res."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib17","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1002\/19960402NT6","article-title":"Toosendanin facilitates [3H] noradrenaline release from rat hippocampal slices","volume":"4","author":"Huang","year":"1996","journal-title":"Nat. Toxins"},{"key":"10.1016\/j.pneurobio.2007.02.002_bib18","first-page":"385","article-title":"Effects of toosendanin on the fine structure of the mouse neuromuscular junction","volume":"32","author":"Huang","year":"1980","journal-title":"Acta Physiol. Sin."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib19","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1098\/rspb.1977.0029","article-title":"Transmitter leakage from motor nerve endings","volume":"196","author":"Katz","year":"1977","journal-title":"Proc. R. Soc. Lond. B Biol. Sci."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib20","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1126\/science.3887571","article-title":"Qinghaosu (artemisinin): an antimalarial drug from China","volume":"228","author":"Klayman","year":"1985","journal-title":"Science"},{"key":"10.1016\/j.pneurobio.2007.02.002_bib21","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1038\/nsb879","article-title":"Translocation of botulinum neurotoxin light chain protease through the heavy chain channel","volume":"10","author":"Koriazova","year":"2003","journal-title":"Nat. Struct. Biol."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib22","first-page":"718","article-title":"Chinaberry seeds combined with synthesized therapeutics saved patients from botulism","volume":"23","author":"Li","year":"2003","journal-title":"Chin. J. Crit. Care. Med."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib23","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.ejphar.2004.08.027","article-title":"Toosendanin, a triterpenoid derivative, acts as a novel agonist of L-type Ca2+ channels in neonatal rat ventricular cells","volume":"501","author":"Li","year":"2004","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib24","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.toxicon.2004.09.010","article-title":"The long-term effect of toosendanin on current through nifedipine-sensitive Ca2+ channels in NG108-15 cells","volume":"45","author":"Li","year":"2005","journal-title":"Toxicon"},{"key":"10.1016\/j.pneurobio.2007.02.002_bib25","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1111\/j.1745-7254.2006.00236.x","article-title":"Toosendanin inhibits pore formation of botulinum toxin type A at PC12 cell membrane","volume":"27","author":"Li","year":"2006","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib26","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.neures.2004.02.012","article-title":"Toosendanin, a triterpenoid derivative, increases Ca2+ current in NG108-15 cells via L-type channels","volume":"49","author":"Li","year":"2004","journal-title":"Neurosci. Res."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib27","first-page":"480","article-title":"Antibotulismic effect of toosendanin to botulinum toxins on neuromuscular preparations of mice","volume":"35","author":"Li","year":"1983","journal-title":"Acta Physiol. Sin."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib28","first-page":"28","article-title":"Therapeutic effect of toosendanin on animal botulism","volume":"13","author":"Li","year":"1982","journal-title":"Chin. Tradit. Herb. Drugs"},{"key":"10.1016\/j.pneurobio.2007.02.002_bib29","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1007\/BF00670529","article-title":"Presynaptic currents in frog motor endings","volume":"400","author":"Mallart","year":"1984","journal-title":"Pflugers. Arch."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib30","first-page":"4034","article-title":"Calcium regulation of neurite elongation and growth cone motility","volume":"7","author":"Nattson","year":"1987","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib31","doi-asserted-by":"crossref","first-page":"1704","DOI":"10.1523\/JNEUROSCI.08-05-01704.1988","article-title":"Neurite outgrowth in individual neurons of a neuronal population is differentially regulated by calcium and cyclic AMP","volume":"8","author":"Nattson","year":"1988","journal-title":"J. Neurosci."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib32","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1113\/jphysiol.1964.sp007447","article-title":"Antidromic activity in the rat phrenic nerve-diaphragm preparation","volume":"173","author":"Randic","year":"1964","journal-title":"J. Physiol."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib33","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1146\/annurev.physiol.64.083101.145105","article-title":"Cardiac ion channels","volume":"64","author":"Roden","year":"2002","journal-title":"Annu. Rev. Physiol."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib34","doi-asserted-by":"crossref","first-page":"10461","DOI":"10.1016\/S0021-9258(19)85105-0","article-title":"Separation, purification, partial characterization and comparison of the heavy and light chains of botulinum neurotoxin types A, B, and E","volume":"260","author":"Sathyamoorthy","year":"1985","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib35","first-page":"546","article-title":"The binding sites of H3-toosendanin in rat cerebral cortex homogenate","volume":"46","author":"Shen","year":"1994","journal-title":"Acta Physiol. Sin."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib36","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/S0041-0101(97)00131-1","article-title":"Gating and permeability of ion channels produced by botulinum toxin types A and E in PC12 cell membranes","volume":"36","author":"Sheridan","year":"1998","journal-title":"Toxicon"},{"key":"10.1016\/j.pneurobio.2007.02.002_bib37","first-page":"677","article-title":"Abolishment of non-quantal release of acetylcholine from the mouse phrenic nerve ending by toosendanin","volume":"33","author":"Shi","year":"1986","journal-title":"Jpn. J. Physiol."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib38","series-title":"Study and Utility of Toxins","first-page":"192","article-title":"Toosendanin, a new presynaptic blocker","author":"Shi","year":"1988"},{"key":"10.1016\/j.pneurobio.2007.02.002_bib39","series-title":"Exploitation and Utility of Biotoxins","article-title":"Chinaberry and toosendanin (in Chinese)","author":"Shi","year":"2007"},{"key":"10.1016\/j.pneurobio.2007.02.002_bib40","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S0006-8993(99)02129-0","article-title":"Effect of Toosendanin on acetylcholine release from rat brain, a microdialysis study","volume":"850","author":"Shi","year":"1999","journal-title":"Brain Res."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib41","first-page":"1489","article-title":"Toosendanin-induced Ca2+ conductance increase in neuroblastoma\u00d7glioma hybrid cells","volume":"38","author":"Shi","year":"1993","journal-title":"Chin. Sci. Bull."},{"issue":"Suppl. 1","key":"10.1016\/j.pneurobio.2007.02.002_bib42","first-page":"44","article-title":"Inhibition of toosendanin on the voltage-dependent K+ current in guinea pig ventricular myocytes","volume":"11","author":"Shi","year":"1992","journal-title":"CAPS News Commu."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib43","first-page":"211","article-title":"Selective binding of toosendanin to synaptosome fraction from rat brain","volume":"34","author":"Shi","year":"1982","journal-title":"Acta Physiol. Sin."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib44","first-page":"461","article-title":"Cell death and apoptosis-induced effect of toosendnin","volume":"20","author":"Shi","year":"2004","journal-title":"Chin. J Neurosci."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib45","first-page":"233","article-title":"Effect of toosendanin on the sensory inputs of chemoreceptors in the armyworm larvae (Mythimne Separata)","volume":"29","author":"Shi","year":"1986","journal-title":"Atca Entomal. Sin."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib46","first-page":"259","article-title":"Electrophysiological analysis on the presynaptic blocking effects of toosendanin on neuromuscular transmission","volume":"33","author":"Shi","year":"1981","journal-title":"Acta Physiol. Sin."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib47","first-page":"304","article-title":"Effects of calcium ions and nerve impulses on changes in miniature end-plate potential frequency produced by toosendanin","volume":"34","author":"Shi","year":"1982","journal-title":"Acta Physiol. Sin."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib48","first-page":"839","article-title":"Cure of experimental botulism and antibotulismic effect of toosendanin","volume":"25","author":"Shi","year":"2004","journal-title":"Acta Pharmacol. Sin."},{"issue":"2","key":"10.1016\/j.pneurobio.2007.02.002_bib49","first-page":"132","article-title":"Toosendanin modifies K+-and Ca2+-channel activity and intracellular Ca2+ concentration","volume":"34","author":"Shi","year":"2007","journal-title":"Prog. Biochem. Biophys."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib50","first-page":"293","article-title":"Toosendanin-a presynaptic neuromuscular blocking agent","volume":"32","author":"Shi","year":"1980","journal-title":"Acta Physiol. Sin."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib51","first-page":"885","article-title":"Antibotulismic effect of toosendanin","volume":"28","author":"Shi","year":"1983","journal-title":"Chin. Sci. Bull."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib52","doi-asserted-by":"crossref","first-page":"677","DOI":"10.2170\/jjphysiol.33.677","article-title":"Anti-botulismic effect of toosendanin and its facilitatory action on miniature end-plate potentials","volume":"33","author":"Shi","year":"1983","journal-title":"Jpn. J. Physiol."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib53","first-page":"141","article-title":"Influence of stimulus frequency, temperature and Ca2+ on onset of toosendanin paralysis of isolated neuromuscular preparations of rats","volume":"33","author":"Shi","year":"1981","journal-title":"Acta Physiol. Sin."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib54","first-page":"196","article-title":"A correction of the structure of Chuanliansu","volume":"38","author":"Shu","year":"1980","journal-title":"Acta Chim. Sin."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib55","series-title":"Botulinum Neurotoxin and Tetanus Toxin","author":"Simpson","year":"1989"},{"key":"10.1016\/j.pneurobio.2007.02.002_bib56","doi-asserted-by":"crossref","first-page":"6349","DOI":"10.1093\/emboj\/18.22.6349","article-title":"Apoptosis driven by IP(3)-linked mitochondria calcium signals","volume":"18","author":"Szalai","year":"1999","journal-title":"EMBO J."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib57","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/S0168-0102(02)00225-0","article-title":"Toosendanin induces outgrowth of neuronal processes and apoptosis in PC12 cells","volume":"45","author":"Tang","year":"2003","journal-title":"Neurosci. Res."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib58","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.tox.2004.03.023","article-title":"Involvement of cytochrome c release and caspase activation in toosendanin-induced apoptosis of PC12 cells","volume":"201","author":"Tang","year":"2004","journal-title":"Toxicology"},{"key":"10.1016\/j.pneurobio.2007.02.002_bib59","series-title":"Chinese Drugs of Plant Origin: Chemistry, Pharmacology, and Use in Traditional and Modern Medicine","author":"Tang","year":"1992"},{"key":"10.1016\/j.pneurobio.2007.02.002_bib60","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/0306-4522(83)90305-6","article-title":"An non-quantal release of acetylcholine at the mouse neuromuscular junction","volume":"9","author":"Vyskocil","year":"1983","journal-title":"Neuroscience"},{"key":"10.1016\/j.pneurobio.2007.02.002_bib61","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S0306-4522(01)00051-3","article-title":"Inhibition of large-conductance Ca2+-activated K+ channel in hippocampal neurons by toosendanin","volume":"104","author":"Wang","year":"2001","journal-title":"Neuroscience"},{"key":"10.1016\/j.pneurobio.2007.02.002_bib62","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/S0168-0102(01)00233-4","article-title":"Modulation of inward rectifier potassium channel by toosendanin, a presynaptic blocker","volume":"40","author":"Wang","year":"2001","journal-title":"Neurosci. Res."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib63","first-page":"313","article-title":"Toosendnin-induced inhibition of small-conductance calcium-activated potassium channels in CA1 pyramidal neurons of rat hippocampus","volume":"30","author":"Wang","year":"2001","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib64","first-page":"46","article-title":"A comprehensive report on clinic ascarid anthelminthic therepeutic effect of toosendanin pills","volume":"262","author":"Wang","year":"1959","journal-title":"J. Tradit. Chin. Med."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib65","first-page":"407","article-title":"Effect of toosendanin on the ultrastructural of the rat neuromuscular junction","volume":"17","author":"Xiong","year":"1982","journal-title":"Yao Xue Xue Bao"},{"key":"10.1016\/j.pneurobio.2007.02.002_bib66","first-page":"495","article-title":"The interaction between toosendanin and botulinum toxin at the neuromuscular junction, an ultrastructural observation","volume":"20","author":"Xiong","year":"1985","journal-title":"Yao Xue Xue Bao"},{"key":"10.1016\/j.pneurobio.2007.02.002_bib67","first-page":"597","article-title":"Toosendanin increased free-Ca2+ concentration in NG108-15 cells via L-type Ca2+ channels","volume":"25","author":"Xu","year":"2004","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib68","first-page":"321","article-title":"Inhibition of glutamate release from rat cerebral synaptosomes by a prejunctional blocker toosendanin","volume":"18","author":"Xu","year":"2004","journal-title":"Chin. J. Pharmacol. Toxicol."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib69","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/0006-8993(93)91184-T","article-title":"Action of toosendanin on the membrane current of motor nerve terminals","volume":"631","author":"Xu","year":"1993","journal-title":"Brain Res."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib70","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1159\/000079339","article-title":"Melia toosendan regulates PC12 Cell differentiation via the activation of protein kinase A and extracellular signal-regulated kinases","volume":"13","author":"Yu","year":"2004","journal-title":"Neurosignals"},{"key":"10.1016\/j.pneurobio.2007.02.002_bib71","first-page":"1","article-title":"An innocuous insecticide, toosendanin","volume":"21","author":"Zhang","year":"1993","journal-title":"Acta Northwe. Uni. Agricult. Sin."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib72","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1007\/s10637-005-0909-5","article-title":"Growth inhibition and apoptosis-induced effect on human cancer cells of toosendanin, a triterpenoid derivative from Chinese traditional medicine","volume":"23","author":"Zhang","year":"2005","journal-title":"Invest. New Drugs"},{"key":"10.1016\/j.pneurobio.2007.02.002_bib73","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1006\/nlme.1997.3767","article-title":"Inhibition of intermediate-term memory following passive avoidance training in neonate chicks by a presynaptic cholinergic blocker","volume":"67","author":"Zhao","year":"1997","journal-title":"Neurobiol. Learn Mem."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib74","first-page":"35","article-title":"The structure of Chuanliansu","volume":"33","author":"Zhong","year":"1975","journal-title":"Acta Chem. Sin."},{"issue":"6","key":"10.1016\/j.pneurobio.2007.02.002_bib75","first-page":"489","article-title":"Inhibition of botulinum toxin's association with rat brain synaptosomes by toosendanin, an antibotulismic triterpenoid","volume":"1","author":"Zhou","year":"2006","journal-title":"Neural Regen. Res."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib76","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/S0014-5793(03)01291-2","article-title":"Antagonism of botulinum toxin type A-induced cleavage of SNAP-25 in rat cerebral synaptosome by toosendanin","volume":"555","author":"Zhou","year":"2003","journal-title":"FEBS Lett."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib77","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/BF01872386","article-title":"Traditional Chinese herbal medicine","volume":"17","author":"Zhu","year":"1995","journal-title":"Pharm. World Sci."},{"key":"10.1016\/j.pneurobio.2007.02.002_bib78","first-page":"24","article-title":"A study on pharmacokinetics of toosendanin","volume":"13","author":"Zou","year":"1982","journal-title":"Chin. Tradit. Herb. Drugs"},{"key":"10.1016\/j.pneurobio.2007.02.002_bib79","first-page":"29","article-title":"The effect of toosendanin on monkey botulism","volume":"5","author":"Zou","year":"1985","journal-title":"J. Tridit. Chin. Med."}],"container-title":["Progress in Neurobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301008207000457?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301008207000457?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,8,8]],"date-time":"2021-08-08T16:55:51Z","timestamp":1628441751000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301008207000457"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,5]]},"references-count":79,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,5]]}},"alternative-id":["S0301008207000457"],"URL":"https:\/\/doi.org\/10.1016\/j.pneurobio.2007.02.002","relation":{},"ISSN":["0301-0082"],"issn-type":[{"value":"0301-0082","type":"print"}],"subject":[],"published":{"date-parts":[[2007,5]]}}}