{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T20:32:43Z","timestamp":1791232363750,"version":"4.1.0"},"reference-count":126,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2012,6,1]],"date-time":"2012-06-01T00:00:00Z","timestamp":1338508800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Progress in Neurobiology"],"published-print":{"date-parts":[[2012,6]]},"DOI":"10.1016\/j.pneurobio.2012.04.005","type":"journal-article","created":{"date-parts":[[2012,5,6]],"date-time":"2012-05-06T04:09:44Z","timestamp":1336277384000},"page":"288-303","source":"Crossref","is-referenced-by-count":51,"title":["The pig model of chronic paraplegia: A challenge for experimental studies in spinal cord injury"],"prefix":"10.1016","volume":"97","author":[{"given":"Mercedes","family":"Zurita","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Concepci\u00f3n","family":"Aguayo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Celia","family":"Bonilla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Otero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel","family":"Rico","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alicia","family":"Rodr\u00edguez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jes\u00fas","family":"Vaquero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.pneurobio.2012.04.005_bib0005","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1016\/j.spinee.2010.09.018","article-title":"Recurrent autonomic dysreflexia exacerbates vascular dysfunction after spinal cord injury","volume":"10","author":"Alan","year":"2010","journal-title":"Spine Journal"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0010","unstructured":"Alc\u00e1ntara, S., Hern\u00e1ndez, M.A., Ortega, E., Sanmart\u00edn, M.V., 1995. Fundamentals of Physiotherapy. Ed. S\u00edntesis, S.A., Madrid (in Spanish)."},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0015","doi-asserted-by":"crossref","first-page":"761","DOI":"10.3233\/RNN-2010-0547","article-title":"Survival of neurally induced mesenchymal cells may determine degree of motor recovery in injured spinal cord rats","volume":"28","author":"Alexanian","year":"2010","journal-title":"Restorative Neurology and Neuroscience"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0020","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1001\/jama.1911.04260090100008","article-title":"Surgery of experimental lesion of spinal cord equivalent to crush injury of fracture dislocation of spinal column: a preliminary report","volume":"57","author":"Allen","year":"1911","journal-title":"Journal of the American Medical Association"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0025","first-page":"540","article-title":"Preliminary trial of carisoprodol in multiple sclerosis","volume":"192","author":"Ashworth","year":"1964","journal-title":"Practitioner"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0030","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1123\/mcj.11.4.322","article-title":"Locomotor behavior of bonnet macaques after spinal cord injury","volume":"11","author":"Babu","year":"2007","journal-title":"Motor Control"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0035","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1152\/jn.1950.13.3.223","article-title":"Lack of regeneration in spinal cord rat","volume":"13","author":"Barnard","year":"1950","journal-title":"Journal of Neurophysiology"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0040","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1089\/neu.1995.12.1","article-title":"A sensitive and reliable locomotor rating scale for open field testing in rats","volume":"12","author":"Basso","year":"1995","journal-title":"Journal of Neurotrauma"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0045","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.tins.2008.09.008","article-title":"Spinal cord injury: plasticity, regeneration and the challenger of traslational drug development","volume":"32","author":"Blesch","year":"2009","journal-title":"Trends in Neurosciences"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0050","series-title":"Spinal Cord Medicine","first-page":"389","article-title":"Pain in patients with spinal cord injury","author":"Bockenek","year":"2002"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0055","doi-asserted-by":"crossref","first-page":"133","DOI":"10.2174\/1568016043477242","article-title":"Cardiovascular alterations after spinal cord injury: an overview","volume":"2","author":"Bravo","year":"2004","journal-title":"Current Medicinal Chemistry \u2013 Cardiovascular & Hematological Agents"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0060","doi-asserted-by":"crossref","first-page":"9728","DOI":"10.1523\/JNEUROSCI.1924-10.2010","article-title":"Local and remote growth factor effects after primate spinal cord injury","volume":"30","author":"Brock","year":"2010","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0065","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1002\/cne.900870204","article-title":"Abortive regeneration of the transacted spinal cord","volume":"87","author":"Brown","year":"1947","journal-title":"Journal of Comparative Neurology"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0070","series-title":"Spinal Cord Medicine","first-page":"123","article-title":"Autonomic and cardiovascular complications of spinal cord injury","author":"Campagnolo","year":"2002"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0075","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1016\/j.transproceed.2008.02.055","article-title":"Functional outcome of bone marrow stem cells (CD45+, CD34\u2212) after cell therapy in acute spinal cord injury: in exercise training and in sedentary rats","volume":"40","author":"Carvalho","year":"2008","journal-title":"Transplantation Proceedings"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0080","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1002\/nau.20929","article-title":"Intermittent catherization with hydrophilic catheters as a treatment of chronic neurogenic urinary retention","volume":"30","author":"Chartier-Kastler","year":"2011","journal-title":"Neurourology and Urodynamics"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0085","series-title":"Spinal Cord Medicine","article-title":"Gastrointestinal disorders","author":"Chen","year":"2002"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0090","doi-asserted-by":"crossref","first-page":"3001","DOI":"10.1097\/00001756-200009110-00035","article-title":"Spinal cord injury in rat: treatment with bone marrow stromal cells transplantation","volume":"11","author":"Chopp","year":"2000","journal-title":"Neuroreport"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0095","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1126\/science.6171034","article-title":"Axonal elongation into peripheral nervous system bridges after central nervous system injury in adults rats","volume":"214","author":"David","year":"1981","journal-title":"Science"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0100","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.neulet.2004.11.060","article-title":"Detection of 111In-oxine-labeled bone marrow stromal cells after intravenous or intralesional administration in chronic paraplegic rats","volume":"377","author":"De Haro","year":"2005","journal-title":"Neuroscience Letters"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0105","first-page":"1533","article-title":"Functional recovery after rhesus monkey spinal cord injury by transplantation of bone marrow mesenchymal stem cell derived neurons","volume":"118","author":"Deng","year":"2005","journal-title":"Chinese Medical Journal (English Edition)"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0110","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1016\/S1388-2457(03)00120-2","article-title":"Spinal cord pattern generations for locomotion","volume":"114","author":"Dietz","year":"2003","journal-title":"Clinical Neurophysiology"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0115","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1038\/sj.sc.3100590","article-title":"Locomotor pattern in paraplegic patients: training effects and recovery of spinal cord function","volume":"36","author":"Dietz","year":"1998","journal-title":"Spinal Cord"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0120","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1212\/01.wnl.0000202600.72018.39","article-title":"Weight-supported treadmill vs over-ground training for walking after acute incomplete SCI","volume":"66","author":"Dobkin","year":"2006","journal-title":"Neurology"},{"issue":"1","key":"10.1016\/j.pneurobio.2012.04.005_bib0125","doi-asserted-by":"crossref","first-page":"e16456","DOI":"10.1371\/journal.pone.0016456","article-title":"Spinal cord injury causes sustained disruption of the blood-testis barrier in the rat","volume":"6","author":"Dulin","year":"2011","journal-title":"PloS One"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0130","doi-asserted-by":"crossref","first-page":"C1124","DOI":"10.1152\/ajpcell.1998.275.4.C1124","article-title":"Early changes in muscle fiber size and gene expression in response to spinal cord transection and exercise","volume":"275","author":"Dupont-Versteegden","year":"1998","journal-title":"American Journal of Physiology"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0135","unstructured":"Esclarin de Ruz, A., 2010. Spinal cord injury: multidisciplinary approach. Ed. Panamericana. Madrid (in Spanish)."},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0140","doi-asserted-by":"crossref","first-page":"2479","DOI":"10.1111\/j.1460-9568.2004.03716.x","article-title":"Regenerating corticospinal fibers in the Marmoset (Callitrix jacchus) after spinal cord lesion and treatment with the anti-Nogo-A antibody IN-1","volume":"20","author":"Fouad","year":"2004","journal-title":"European Journal of Neuroscience"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0145","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0959-4388(00)00178-1","article-title":"Repulsive factors and axon regeneration in the CNS","volume":"11","author":"Fournier","year":"2001","journal-title":"Current Opinion in Neurobiology"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0150","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.expneurol.2004.01.032","article-title":"Partial recovery after treatment of chronic paraplegia in rat","volume":"188","author":"Fraidakis","year":"2004","journal-title":"Experimental Neurology"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0155","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1002\/cne.20204","article-title":"Effects of limb exercise after spinal cord injury on motor neuron dendrite structure","volume":"476","author":"Gazula","year":"2004","journal-title":"Journal of Comparative Neurology"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0160","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1021\/nn102461w","article-title":"Transplantation of nanostructured composite scaffolds results in the regeneration of chronically injured spinal cords","volume":"5","author":"Gelain","year":"2011","journal-title":"ACS Nano"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0165","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1146\/annurev.neuro.23.1.579","article-title":"The relationship between neuronal survival and regeneration","volume":"23","author":"Goldberg","year":"2000","journal-title":"Annual Review of Neuroscience"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0170","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1089\/neu.2006.0219","article-title":"Overground locomotion after incomplete spinal lesions in the rat: quantitative gait analysis","volume":"24","author":"Gorska","year":"2007","journal-title":"Journal of Neurotrauma"},{"issue":"196","key":"10.1016\/j.pneurobio.2012.04.005_bib0175","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1016\/j.bbr.2008.09.019","article-title":"Recovery of overground locomotion following partial spinal lesions of different extent in the rat","volume":"23","author":"Gorska","year":"2009","journal-title":"Behavioural Brain Research"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0180","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1152\/physrev.1975.55.2.247","article-title":"Locomotion in vertebrates: central mechanisms and reflex interaction","volume":"55","author":"Grillner","year":"1975","journal-title":"Physiological Reviews"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0185","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1146\/annurev.ne.08.030185.001313","article-title":"Central pattern generators for locomotion, with special reference to vertebrates","volume":"8","author":"Grillner","year":"1985","journal-title":"Annual Review of Neuroscience"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0190","unstructured":"Guttmann, L.S., 1981. Spinal Cord Injury. Comprehensive treatment and research. Ed. JIMS. Barcelona (in Spanish)."},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0195","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1111\/j.1600-0404.2011.01547.x","article-title":"Cardiovascular and urological dysfunction in spinal cord injury","volume":"191","author":"Hagen","year":"2011","journal-title":"Acta Neurologica Scandinavica Supplementum"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0200","doi-asserted-by":"crossref","first-page":"50","DOI":"10.3171\/spi.2005.2.1.0050","article-title":"Postoperative fibrosis after surgical treatment of the porcine spinal cord: a comparison of dural substitutes. Invited submission from the Joint Section Meeting on Disorders of the Spine and Peripheral Nerves, March 2004","volume":"2","author":"Haq","year":"2005","journal-title":"Journal of Neurosurgery: Spine"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0205","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1097\/BRS.0b013e3181fd6b36","article-title":"Neurological improvement after thoracic, thoracolumbar, and lumbar spinal cord (conus medullaris) injuries","volume":"1","author":"Harrop","year":"2011","journal-title":"Spine (Phila Pa 1976)"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0210","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/S0195-5616(92)50632-5","article-title":"Postoperative analgesia","volume":"22","author":"Haskins","year":"1992","journal-title":"Veterinary Clinics of North America: Small Animal Practice"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0215","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/S0195-5616(92)50634-9","article-title":"The case against the routine use of analgesics","volume":"22","author":"Haskins","year":"1992","journal-title":"Veterinary Clinics of North America: Small Animal Practice"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0220","unstructured":"Henke, J., Erhardt, W., 2004. How to recognize pain in animals? In: Control of pain in small animals and pets. Ed. Masson, Barcelona (in Spanish)."},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0225","first-page":"156","article-title":"Electrical stimulation of reinnervating rat muscle","author":"Herbison","year":"1973","journal-title":"Archives of Physical Medicine and Rehabilitation^pV 54"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0230","doi-asserted-by":"crossref","first-page":"2199","DOI":"10.1073\/pnas.042678299","article-title":"Marrow stromal cells form guiding strands in the injured spinal cord and promote recovery","volume":"99","author":"Hofstetter","year":"2002","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0235","doi-asserted-by":"crossref","first-page":"169","DOI":"10.3171\/2010.3.SPINE09190","article-title":"Glial scar and neuroregeneration: histological, functional, and magnetic resonance imaging analysis in chronic spinal cord injury","volume":"13","author":"Hu","year":"2010","journal-title":"Journal of Neurosurgery: Spine"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0240","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1093\/brain\/awh160","article-title":"Three exercise paradigms differentially improve sensory recovery after spinal cord contusion in rats","volume":"127","author":"Hutchinson","year":"2004","journal-title":"Brain"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0245","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/S0306-4522(01)00436-5","article-title":"Autonomic dysreflexia in a mouse model of spinal cord injury","volume":"108","author":"Jacob","year":"2001","journal-title":"Neuroscience"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0250","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1111\/j.1749-6632.1998.tb09040.x","article-title":"Initiation of locomotion in mammals","volume":"860","author":"Jordan","year":"1998","journal-title":"Annals of the New York Academy of Sciences"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0255","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1089\/08977150252806947","article-title":"Development and characterization of a novel, graded model of clip compressive spinal cord injury in the mouse: Part 1. Clip design, behavioural outcomes and histopathology","volume":"19","author":"Joshi","year":"2002","journal-title":"Journal of Neurotrauma"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0260","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1089\/08977150252806956","article-title":"Development and characterization of a novel, graded model of clip compressive spinal cord injury in the mouse: Part 2. Quantitative neuroanatomical assessment and analysis of the relationships between axonal tracts, residual tissue and locomotor recovery","volume":"19","author":"Joshi","year":"2002","journal-title":"Journal of Neurotrauma"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0265","doi-asserted-by":"crossref","first-page":"745","DOI":"10.3171\/jns.1977.46.6.0745","article-title":"The mechanism of spinal cord cavitation following spinal cord transaction.II. Electron microscopic observations","volume":"46","author":"Kao","year":"1977","journal-title":"Journal of Neurosurgery"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0270","doi-asserted-by":"crossref","first-page":"1811","DOI":"10.1016\/j.apmr.2004.03.015","article-title":"Late neurologic recovery after traumatic spinal cord injury","volume":"85","author":"Kirshblum","year":"2004","journal-title":"Archives of Physical Medicine and Rehabilitation"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0275","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1177\/1545968310369801","article-title":"Case control series of intrathecal autologous bone marrow mesenchymal stem cell therapy for chronic spinal cord injury","volume":"24","author":"Kishk","year":"2010","journal-title":"Neurorehabilitation & Neural Repair"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0280","unstructured":"K\u00f6nig, H.E., 2004. Anatomy of pets. Editorial Panamericana, Madrid (in Spanish)."},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0285","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.expneurol.2010.03.008","article-title":"Task-specificity vs. ceiling effect: step-training in shallow water after spinal cord injury","volume":"224","author":"Kuerzi","year":"2010","journal-title":"Experimental Neurology"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0290","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1080\/10790268.2010.11689673","article-title":"Pediatric spinal cord injury in infant piglet: description of a new large animal model and review of the literature","volume":"33","author":"Kuluz","year":"2010","journal-title":"Journal of Spinal Cord Medicine"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0295","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1006\/exnr.1993.1017","article-title":"Methods to assess the development and recovery of locomotor function after spinal cord injury in rats","volume":"119","author":"Kunkel-Bagden","year":"1993","journal-title":"Experimental Neurology"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0300","doi-asserted-by":"crossref","first-page":"360","DOI":"10.4321\/S1130-14732009000400004","article-title":"Comparison of Oxiplex and Gore-Tex effectivity in an experimental peridural fibrosis model","volume":"20","author":"Kurt","year":"2009","journal-title":"Neurocirug\u00eda"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0305","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1177\/1545968309335976","article-title":"Effect of treadmill training on autonomic dysreflexia in spinal cord injured rats","volume":"23","author":"Laird","year":"2009","journal-title":"Neurorehabilitation & Neural Repair"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0310","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/0304-3959(81)90190-1","article-title":"The deafferentation syndrome in monkeys: dysesthesias of spinal origin","volume":"10","author":"Levitt","year":"1981","journal-title":"Pain"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0315","doi-asserted-by":"crossref","first-page":"10514","DOI":"10.1523\/JNEUROSCI.18-24-10514.1998","article-title":"Regeneration of adult rat corticospinal axons induced by transplanted olfactory ensheathing cells","volume":"18","author":"Li","year":"1998","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0320","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1089\/cell.2010.0039","article-title":"Development a model of sacrocaudal spinal cord injury in cloned Yucatan minipig for cellular transplantation research","volume":"12","author":"Lim","year":"2010","journal-title":"Cellular Reprogramming"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0325","series-title":"Spinal Cord Medicine","first-page":"181","article-title":"Neurogenic bladder following spinal cord injury","author":"Lisenmeyer","year":"2002"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0330","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1097\/00007632-200204150-00021","article-title":"Olfactory ensheathing cells: their potential use for repaiting the injured spinal cord","volume":"27","author":"Lu","year":"2002","journal-title":"Spine"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0335","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1093\/brain\/awf014","article-title":"Olfactory ensheathing cells promote recovery after delayed transplantation into transected spinal cord","volume":"125","author":"Lu","year":"2002","journal-title":"Brain"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0340","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.expneurol.2006.07.030","article-title":"Axon regeneration through scars and into sites of chronic spinal cord injury","volume":"203","author":"Lu","year":"2007","journal-title":"Experimental Neurology"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0635","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1089\/neu.2010.1423","article-title":"Combined VEGF and PDGF treatment reduces secondary degeneration after spinal cord injury","volume":"29","author":"Lutton","year":"2012","journal-title":"Journal of Neurotrauma"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0350","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1186\/1471-2202-10-144","article-title":"Exercise-induced motor improvement after complete spinal cord transection and its relation to expression of brain-derived neurotrophic factor and presynaptic markers","volume":"10","author":"Macias","year":"2009","journal-title":"BMC Neuroscience"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0355","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1177\/1545968308331147","article-title":"Swimming as a model of task-specific locomotor retraining after spinal cord injury in the rat","volume":"23","author":"Magnuson","year":"2009","journal-title":"Neurorehabilitation & Neural Repair"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0360","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1016\/S0003-9993(99)90251-4","article-title":"Long-term medical complications after traumatic spinal cord injury: a regional model systems analysis","volume":"80","author":"McKinley","year":"1999","journal-title":"Archives of Physical Medicine and Rehabilitation"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0365","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1067\/mva.2000.107571","article-title":"Prevention of paraplegia in pigs by segmental artery perfusion during aortic cross clamping","volume":"32","author":"Meylaerdts","year":"2000","journal-title":"Journal of Vascular Surgery"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0370","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/S0079-6123(02)37024-9","article-title":"Chondroitin sulphate proteoglycans in the CNS injury response","volume":"137","author":"Morgenstern","year":"2002","journal-title":"Progress in Brain Research"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0375","unstructured":"Muir, W.W., Hubbell, J.A., Skarda, R.T., Bednarski, R.M., 2003. Procedures and anesthetic techniques in swine. In: Manual of Veterinary Anesthesia. Harcourt, Madrid, pp. 352\u2013358 (in Spanish)."},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0380","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1089\/089771503767869935","article-title":"The effect of treadmill training on motor recovery after a partial spinal cord compression injury in the adult rat","volume":"20","author":"Multon","year":"2003","journal-title":"Journal of Neurotrauma"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0385","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1097\/NEN.0b013e3181c34bbe","article-title":"Chronic spinal injury repair by olfactory bulb ensheating glia and feasibility for autologous therapy","volume":"68","author":"Mu\u00f1oz-Quiles","year":"2009","journal-title":"Journal of Neuropathology and Experimental Neurology"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0390","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1152\/jn.00970.2004","article-title":"Reduced functional recovery by delaying motor training after spinal cord injury","volume":"94","author":"Norrie","year":"2005","journal-title":"Journal of Neurophysiology"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0395","series-title":"Spinal Cord Medicine","first-page":"207","article-title":"Pressure ulcers and spinal cord injury","author":"O\u2019Connor","year":"2002"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0400","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1093\/ilar.47.4.364","article-title":"Establishing an appropriate period of acclimatization following transportation of laboratory animals","volume":"47","author":"Obernier","year":"2006","journal-title":"ILAR Journal"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0405","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.expneurol.2004.01.021","article-title":"Bone marrow stromal cells infused into the cerebrospinal fluid promote functional recovery of the injured rat spinal cord with reduced cavity formation","volume":"187","author":"Ohta","year":"2004","journal-title":"Experimental Neurology"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0410","doi-asserted-by":"crossref","first-page":"792","DOI":"10.3109\/14653249.2010.487899","article-title":"Functional recovery after transplantation of bone marrow-derived human mesenchymal stromal cells in a rat model of spinal cord injury","volume":"12","author":"Pal","year":"2010","journal-title":"Cythoterapy"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0415","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1038\/sj.bmt.1705757","article-title":"Bone marrow-derived mesenchyal stromal cells for the repair of central nervous system injury","volume":"40","author":"Parr","year":"2007","journal-title":"Bone Marrow Transplantation"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0420","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1146\/annurev.ne.16.030193.001405","article-title":"Common principles of motor control in vertebrates and invertebrates","volume":"16","author":"Pearson","year":"1993","journal-title":"Annual Review of Neuroscience"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0425","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1056\/NEJM198906083202303","article-title":"Intrathecal baclofen for severe spinal spasticity","volume":"320","author":"Penn","year":"1989","journal-title":"New England Journal of Medicine"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0430","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.neures.2010.11.002","article-title":"Clinical care evolution of paraplegic monkeys (Macaca Mulatta) over fourteen months post-lesion","volume":"69","author":"Piedras","year":"2011","journal-title":"Neuroscience Research"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0435","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1259\/bjr\/11881183","article-title":"Pictorial review: MRI of chronic spinal cord injury","volume":"76","author":"Potter","year":"2003","journal-title":"British Journal of Radiology"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0440","unstructured":"Ram\u00f3n y Cajal, S., 1914. Studies on the degeneration and regeneration of nervous system, vol. II. Printing Nicholas Moya Sons, Madrid (in Spanish)."},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0445","unstructured":"Ram\u00f3n y Cajal, S. 1991. Degeneration and Regeneration of the Nervous System. De Felipe and E.G. Jones (Eds.), Oxford University Press, New York."},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0450","doi-asserted-by":"crossref","first-page":"1709","DOI":"10.1089\/neu.2010.1382","article-title":"Care of rats with complete high-thoracic spinal cord injury","volume":"27","author":"Ramsey","year":"2010","journal-title":"Journal of Neurotrauma"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0455","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/S0166-2236(97)01139-9","article-title":"Reactive astrocytes: cellular and molecular cues to biological function","volume":"20","author":"Ridet","year":"1997","journal-title":"Trends in Neuroscience"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0460","first-page":"38","article-title":"Effect of duration of acute spinal cord compression in a new acute cord injury model in the rat","volume":"10","author":"Rivlin","year":"1978","journal-title":"Surgical Neurology"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0465","doi-asserted-by":"crossref","first-page":"E1273","DOI":"10.1097\/BRS.0b013e3181e3fc5f","article-title":"The effects of different rehabilitation strategies on the functional recovery of spinal cord injured rats: an experimental study","volume":"35","author":"Robert","year":"2010","journal-title":"Spine (Phila Pa 1976)"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0470","unstructured":"Rodr\u00edguez-Boto, G., Vaquero, J., 2009. Spinal cord trauma. Ed. D\u00edaz de Santos, Madrid (in Spanish)."},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0475","unstructured":"Roldan, A., 2002. Nursing and Injured Spinal Cord. Ed. Asepeyo, Madrid (in Spanish)."},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0480","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1002\/cne.21940","article-title":"Extensive spinal decussation and bilateral termination of cervical corticospinal projections in rhesus monkeys","volume":"513","author":"Rosenzweig","year":"2009","journal-title":"Journal of Comparative Neurology"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0485","doi-asserted-by":"crossref","first-page":"1505","DOI":"10.1038\/nn.2691","article-title":"Extensive spontaneous plasticity of corticospinal projections after primate spinal cord injury","volume":"13","author":"Rosenzweig","year":"2010","journal-title":"Nature Neuroscience"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0490","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1089\/neu.2006.23.521","article-title":"Long term care of paraplegic laboratory mammals","volume":"23","author":"Santos-Benito","year":"2006","journal-title":"Journal of Neurotrauma"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0495","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1146\/annurev.ne.16.030193.003025","article-title":"Inhibitors of neurite growth","volume":"16","author":"Schwab","year":"1993","journal-title":"Annual Review of Neuroscience"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0500","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1038\/nrn1326","article-title":"Regeneration beyond the glial scar","volume":"5","author":"Silver","year":"2004","journal-title":"Nature Reviews Neuroscience"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0505","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1089\/neu.2006.23.908","article-title":"Effects of swimming on functional recovery after incomplete spinal cord injury in rats","volume":"23","author":"Smith","year":"2006","journal-title":"Journal of Neurotrauma"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0510","unstructured":"Sopena, J., Sanju\u00e1n, A., Carrillo, J.M., Garc\u00eda, M., Mazo, R., Ortiz, M.L., Rubio, M., S\u00e1nchez de la Muela, M., Whyte, A., 2009. General management of skin wounds. In: Management of wounds and principles of plastic surgery in small animals Ed. Servet, Zaragoza, pp. 62\u201370 (in Spanish)."},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0515","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1016\/j.ejcts.2004.01.007","article-title":"Mild hypothermia protects the spinal cord from ischemic injury in a chronic porcine model","volume":"25","author":"Strauch","year":"2004","journal-title":"European Journal of Cardiothoracic Surgery"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0520","series-title":"Swine in the Laboratory: Surgery, Anesthesia, Imaging, and Experimental Techniques","author":"Swindle","year":"2007"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0525","doi-asserted-by":"crossref","first-page":"6670","DOI":"10.1523\/JNEUROSCI.22-15-06670.2002","article-title":"Schwann cell but not olfactory ensheathing glia transplants improve hindlimb locomotor performance in the moderately contused adult rat thoracic spinal cord","volume":"22","author":"Takami","year":"2002","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0530","series-title":"Spinal Cord Compression: Mechanism of Paralysis and Treatment","author":"Tarlov","year":"1957"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0535","first-page":"63","article-title":"Recovery of locomotor function after treadmill training of incomplete spinal cord injured rats","volume":"37","author":"Thota","year":"2001","journal-title":"Biomedical Sciences Instrumentation"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0540","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/S0079-6123(02)38089-0","article-title":"New strategies in neural repair","volume":"138","author":"Tuszynski","year":"2002","journal-title":"Progress in Brain Research"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0545","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1002\/cne.10266","article-title":"Spontaneous and augmented growth of axons in the primate spinal cord: effects of local injury and nerve growth factor-secreting cell grafts","volume":"449","author":"Tuszynski","year":"2002","journal-title":"Journal of Comparative Neurology"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0550","first-page":"145","article-title":"Effect of polytetrafluoroethylene prosthesis on epidural scar in spinal surgery","volume":"10","author":"Vaquero","year":"1999","journal-title":"Mapfre Medicine"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0555","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.pneurobio.2010.12.002","article-title":"Functional recovery after severe CNS trauma: current perspectives for cell therapy with bone marrow stromal cells","volume":"93","author":"Vaquero","year":"2011","journal-title":"Progress in Neurobiology"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0560","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1002\/glia.10217","article-title":"Olfactory ensheathing cells transplanted in lesioned spinal cord prevent loss of spinal cord parenchyma and promote functional recovery","volume":"42","author":"Verd\u00fa","year":"2003","journal-title":"Glia"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0565","unstructured":"Vidal, J., 2009. Neurorehabilitation treatment of traumatic spinal cord injury. In: Spinal cord trauma. Ed. D\u00edaz de Santos, Madrid, pp. 325\u2013336 (in Spanish)."},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0570","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1111\/j.1749-6632.1998.tb09095.x","article-title":"Stepping in nonhuman primates with a complete spinal cord transection: old and new data, and implications for humans","volume":"860","author":"Vilensky","year":"1998","journal-title":"Annals of the New York Academy of Sciences"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0575","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/S0079-6123(05)52016-8","article-title":"Autonomic dysreflexia after spinal cord injury: central mechanisms and strategies for prevention","volume":"152","author":"Weaver","year":"2006","journal-title":"Progress in Brain Research"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0580","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1038\/sc.1992.61","article-title":"Laufband locomotion with body weight support improved walking in persons with severe spinal cord injuries","volume":"30","author":"Wernig","year":"1992","journal-title":"Paraplegia"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0585","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1111\/j.1460-9568.1995.tb00686.x","article-title":"Laufband therapy based on rules of spinal locomotion is effective in spinal cord injured persons","volume":"7","author":"Wernig","year":"1995","journal-title":"European Journal of Neuroscience"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0590","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.neulet.2011.01.009","article-title":"Implanted spike wave electric stimulation promotes survival of the bone marrow mesenchynal stem cells and functional recovery in the spinal cord injuried rats","volume":"491","author":"Wu","year":"2011","journal-title":"Neuroscience Letters"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0595","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/0306-4530(85)90043-5","article-title":"Habituation of the prolactin response in rats to psychological stress","volume":"10","author":"Yelvington","year":"1985","journal-title":"Psychoneuroendocrin"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0600","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1007\/s12028-010-9364-z","article-title":"Acute changes in systemic hemodynamics and serum vasopressin after complete cervical spinal cord injury in piglets","volume":"13","author":"Zahra","year":"2010","journal-title":"Neurocritical Care"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0605","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1159\/000020133","article-title":"Audit of early bladder management complications after spinal cord injury in first treating hospitals","volume":"37","author":"Zermann","year":"2000","journal-title":"European Urology"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0610","first-page":"107","article-title":"Factors influencing axon regeneration after CNS damage","volume":"35","author":"Zhao","year":"2004","journal-title":"Sheng Li Ke Xue Jin Zhan"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0615","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1007\/s11064-010-0377-y","article-title":"KPC1 expression and essential role after acute spinal cord injury in adult rat","volume":"36","author":"Zhao","year":"2011","journal-title":"Neurochemical Research"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0620","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1097\/00001756-200405190-00004","article-title":"Functional recovery in chronic paraplegia after bone marrow stromal cells transplantation","volume":"15","author":"Zurita","year":"2004","journal-title":"Neuroreport"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0625","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.neulet.2006.03.069","article-title":"Bone marrow stromal cells can achieve cure of chronic paraplegic rats: functional and morphological outcome one year after transplantation","volume":"402","author":"Zurita","year":"2006","journal-title":"Neuroscience Letters"},{"key":"10.1016\/j.pneurobio.2012.04.005_bib0630","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1097\/TP.0b013e318186198f","article-title":"Functional recovery of chronic paraplegic pigs after autologous transplantation of bone marrow stromal cells","volume":"86","author":"Zurita","year":"2008","journal-title":"Transplantation"}],"container-title":["Progress in Neurobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301008212000627?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301008212000627?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,7,7]],"date-time":"2020-07-07T05:28:47Z","timestamp":1594099727000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301008212000627"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,6]]},"references-count":126,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,6]]}},"alternative-id":["S0301008212000627"],"URL":"https:\/\/doi.org\/10.1016\/j.pneurobio.2012.04.005","relation":{},"ISSN":["0301-0082"],"issn-type":[{"value":"0301-0082","type":"print"}],"subject":[],"published":{"date-parts":[[2012,6]]}}}