{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T13:22:32Z","timestamp":1765545752298},"reference-count":47,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2012,8,1]],"date-time":"2012-08-01T00:00:00Z","timestamp":1343779200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Progress in Neuro-Psychopharmacology and Biological Psychiatry"],"published-print":{"date-parts":[[2012,8]]},"DOI":"10.1016\/j.pnpbp.2012.03.013","type":"journal-article","created":{"date-parts":[[2012,4,4]],"date-time":"2012-04-04T19:34:58Z","timestamp":1333568098000},"page":"207-215","source":"Crossref","is-referenced-by-count":26,"title":["Salutary effect of NF\u03baB inhibitor and folacin in hyperhomocysteinemia\u2013hyperlipidemia induced vascular dementia"],"prefix":"10.1016","volume":"38","author":[{"given":"Bhupesh","family":"Sharma","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nirmal","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.pnpbp.2012.03.013_bb0005","doi-asserted-by":"crossref","first-page":"270","DOI":"10.4103\/0250-474X.56025","article-title":"Effect of folic acid on hematological changes in methionine-induced hyperhomocysteinemia in rats","volume":"71","author":"Ansari","year":"2009","journal-title":"Indian J Pharm Sci"},{"issue":"8","key":"10.1016\/j.pnpbp.2012.03.013_bb0010","doi-asserted-by":"crossref","first-page":"678","DOI":"10.18632\/aging.100080","article-title":"Role of NF\u03baB in age-related vascular endothelial dysfunction in humans","volume":"1","author":"Anthony","year":"2009","journal-title":"Aging"},{"key":"10.1016\/j.pnpbp.2012.03.013_bb0015","first-page":"1","article-title":"B vitamins and berries and age-related neurodegenerative disorders","volume":"134","author":"Balk","year":"2006","journal-title":"Evid Rep Technol Assess"},{"key":"10.1016\/j.pnpbp.2012.03.013_bb0020","first-page":"82","article-title":"Reduced glutathione estimation","volume":"61","author":"Beutler","year":"1963","journal-title":"J Lab Clin Med"},{"issue":"9","key":"10.1016\/j.pnpbp.2012.03.013_bb0025","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1001\/archneurol.2011.100","article-title":"Risk factors and preventive interventions for Alzheimer disease, state of the science","volume":"68","author":"Daviglus","year":"2011","journal-title":"Arch Neurol"},{"key":"10.1016\/j.pnpbp.2012.03.013_bb0030","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/S0008-6363(01)00403-5","article-title":"Estradiol prevents homocysteine induced endothelial injury in male rats","volume":"53","author":"Dimitrova","year":"2002","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.pnpbp.2012.03.013_bb0035","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/0006-2952(61)90145-9","article-title":"A new and rapid colorimetric determination of acetylcholinesterase activity","volume":"7","author":"Ellman","year":"1961","journal-title":"Biochem Pharmacol"},{"key":"10.1016\/j.pnpbp.2012.03.013_bb0040","doi-asserted-by":"crossref","first-page":"401604","DOI":"10.4061\/2011\/401604","article-title":"Neurobiology of vascular dementia","volume":"2011","author":"Enciu","year":"2011","journal-title":"J Aging Res"},{"key":"10.1016\/j.pnpbp.2012.03.013_bb0045","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1186\/1471-2202-9-62","article-title":"NF-kappaB activation is associated with homocysteine-induced injury in Neuro2a cells","volume":"9","author":"Ferlazzo","year":"2008","journal-title":"BMC Neurosci"},{"issue":"4","key":"10.1016\/j.pnpbp.2012.03.013_bb0050","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.arr.2010.04.007","article-title":"Metabolic-cognitive syndrome, a cross-talk between metabolic syndrome and Alzheimer's disease","volume":"9","author":"Frisardi","year":"2010","journal-title":"Ageing Res Rev"},{"issue":"1","key":"10.1016\/j.pnpbp.2012.03.013_bb0055","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/s10072-011-0645-x","article-title":"Cognitive and neurochemical alterations in hyperhomocysteinemic rat","volume":"33","author":"Gao","year":"2012","journal-title":"Neurol Sci"},{"issue":"4","key":"10.1016\/j.pnpbp.2012.03.013_bb0060","doi-asserted-by":"crossref","first-page":"809","DOI":"10.3233\/JAD-2009-0976","article-title":"Inflammation and NF-kappaB in Alzheimer's disease and diabetes","volume":"16","author":"Granic","year":"2009","journal-title":"J Alzheimers Dis"},{"issue":"3","key":"10.1016\/j.pnpbp.2012.03.013_bb0065","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1515\/CCLM.2011.084","article-title":"Homocysteine, a biomarker in neurodegenerative diseases","volume":"49","author":"Herrmann","year":"2011","journal-title":"Clin Chem Lab Med"},{"issue":"1","key":"10.1016\/j.pnpbp.2012.03.013_bb0070","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1161\/HYPERTENSIONAHA.110.160929","article-title":"25-Hydroxyvitamin D deficiency is associated with inflammation-linked vascular endothelial dysfunction in middle-aged and older adults","volume":"57","author":"Jablonski","year":"2011","journal-title":"Hypertension"},{"issue":"2","key":"10.1016\/j.pnpbp.2012.03.013_bb0075","doi-asserted-by":"crossref","first-page":"S74","DOI":"10.1111\/j.1753-4887.2010.00352.x","article-title":"Vascular basis for brain degeneration faltering controls and risk factors for dementia","volume":"68","author":"Kalaria","year":"2010","journal-title":"Nutr Rev"},{"issue":"11","key":"10.1016\/j.pnpbp.2012.03.013_bb0080","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1016\/j.freeradbiomed.2009.09.008","article-title":"l-Theanine an amino acid in green tea attenuates beta-amyloid-induced cognitive dysfunction and neurotoxicity reduction in oxidative damage and inactivation of ERK\/p38 kinase and NF-kappaB pathways","volume":"47","author":"Kim","year":"2009","journal-title":"Free Radic Biol Med"},{"issue":"6","key":"10.1016\/j.pnpbp.2012.03.013_bb0085","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.exger.2010.03.005","article-title":"Modulation of age-related NF-kappaB activation by dietary zingerone via MAPK pathway","volume":"45","author":"Kim","year":"2010","journal-title":"Exp Gerontol"},{"key":"10.1016\/j.pnpbp.2012.03.013_bb0090","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/1471-2210-8-14","article-title":"Ameliorative role of atorvastatin and pitavastatin in l-methionine induced vascular dementia in rats","volume":"8","author":"Koladiya","year":"2008","journal-title":"BMC Pharmacol"},{"key":"10.1016\/j.pnpbp.2012.03.013_bb0095","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1248\/jhs.55.215","article-title":"Beneficial effects of donepezil on vascular endothelial dysfunction-associated dementia induced by l-methionine in rats","volume":"552","author":"Koladiya","year":"2009","journal-title":"J. Health Sci"},{"issue":"1","key":"10.1016\/j.pnpbp.2012.03.013_bb0100","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/s12012-010-9094-7","article-title":"Homocysteine induces oxidative\u2013nitrative stress in heart of rats, prevention by folic acid","volume":"11","author":"Kolling","year":"2011","journal-title":"Cardiovasc Toxicol"},{"issue":"3","key":"10.1016\/j.pnpbp.2012.03.013_bb0105","doi-asserted-by":"crossref","first-page":"315","DOI":"10.2174\/156652409787847146","article-title":"Folic acid, neurodegenerative and neuropsychiatric disease","volume":"9","author":"Kronenberg","year":"2009","journal-title":"Curr Mol Med"},{"issue":"2","key":"10.1016\/j.pnpbp.2012.03.013_bb0110","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.pbb.2008.12.012","article-title":"Suppression of NF-kappabeta signaling pathway by tocotrienol can prevent diabetes associated cognitive deficits","volume":"92","author":"Kuhad","year":"2009","journal-title":"Pharmacol Biochem Behav"},{"issue":"2","key":"10.1016\/j.pnpbp.2012.03.013_bb0115","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.bcp.2011.04.001","article-title":"Ginsenoside Rb1 prevents homocysteine-induced endothelial dysfunction via PI3K\/Akt activation and PKC inhibition","volume":"82","author":"Lan","year":"2011","journal-title":"Biochem Pharmacol"},{"key":"10.1016\/j.pnpbp.2012.03.013_bb0120","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","article-title":"Protein measurement with folin\u2013phenol reagent","volume":"193","author":"Lowry","year":"1951","journal-title":"J Biol Chem"},{"issue":"4","key":"10.1016\/j.pnpbp.2012.03.013_bb0125","first-page":"CD004514","article-title":"Folic acid with or without vitamin B12 for the prevention and treatment of healthy elderly and demented people","author":"Malouf","year":"2008","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.pnpbp.2012.03.013_bb0130","doi-asserted-by":"crossref","first-page":"250970","DOI":"10.4061\/2011\/250970","article-title":"Cardiovascular prevention of cognitive decline","volume":"2011","author":"Monsuez","year":"2011","journal-title":"Cardiol Res Pract"},{"key":"10.1016\/j.pnpbp.2012.03.013_bb0135","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/0165-0270(84)90007-4","article-title":"Developments of a water maze producer for studying spatial learning in the rats","volume":"11","author":"Morris","year":"1984","journal-title":"J Neurosci Methods"},{"issue":"1","key":"10.1016\/j.pnpbp.2012.03.013_bb0140","doi-asserted-by":"crossref","first-page":"F98","DOI":"10.1152\/ajprenal.00386.2010","article-title":"Exercise reduces oxidative stress but does not alleviate hyperinsulinemia or renal dopamine D1 receptor dysfunction in obese rats","volume":"300","author":"Muhammad","year":"2011","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1016\/j.pnpbp.2012.03.013_bb0150","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/0003-2697(79)90738-3","article-title":"Assay for lipid peroxided in animal tissues by thiobarbituric acid reaction","volume":"95","author":"Ohokawa","year":"1979","journal-title":"Anal Biochem"},{"issue":"4","key":"10.1016\/j.pnpbp.2012.03.013_bb0155","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1089\/jmf.2007.0146","article-title":"Methionine supplementation accelerates oxidative stress and nuclear factor kappaB activation in livers of C57BL\/6 mice","volume":"11","author":"Park","year":"2008","journal-title":"J Med Food"},{"issue":"7","key":"10.1016\/j.pnpbp.2012.03.013_bb0240","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1248\/yakushi.127.1125","article-title":"Reversal of memory deficits by Atorvastatin and Simvastatin in rats","volume":"127","author":"Parle","year":"2007","journal-title":"Yakugaku Zasshi"},{"issue":"2","key":"10.1016\/j.pnpbp.2012.03.013_bb0160","doi-asserted-by":"crossref","first-page":"203","DOI":"10.4103\/0253-7613.77371","article-title":"Antihyperhomocysteinemic and antihyperlipidemic effect of Trichilia connaroides in methionine-induced hyperhomocysteinemic animals","volume":"43","author":"Prasanna","year":"2011","journal-title":"Indian J Pharmacol"},{"issue":"10","key":"10.1016\/j.pnpbp.2012.03.013_bb0165","doi-asserted-by":"crossref","first-page":"2712","DOI":"10.1002\/jcp.22621","article-title":"Folic acid improves acetylcholine-induced vasoconstriction of coronary vessels isolated from hyperhomocysteinemic mice, an implication to coronary vasospasm","volume":"226","author":"Qipshidze","year":"2011","journal-title":"J Cell Physiol"},{"key":"10.1016\/j.pnpbp.2012.03.013_bb0170","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/j.neuroscience.2011.07.002","article-title":"Pharmacological investigations on potential of peroxisome proliferator-activated receptor-gamma agonists in hyperhomocysteinemia-induced vascular dementia in rats","volume":"192","author":"Sain","year":"2011","journal-title":"Neuroscience"},{"issue":"8","key":"10.1016\/j.pnpbp.2012.03.013_bb0175","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1681\/ASN.2010020218","article-title":"NF-kappaB in renal inflammation","volume":"21","author":"Sanz","year":"2010","journal-title":"J Am Soc Nephrol"},{"issue":"1","key":"10.1016\/j.pnpbp.2012.03.013_bb0180","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1006\/abio.2002.5676","article-title":"Spectrophotometric determination of serum nitrite and nitrate by copper\u2013cadmium alloy","volume":"306","author":"Sastry","year":"2002","journal-title":"Anal Biochem"},{"issue":"3","key":"10.1016\/j.pnpbp.2012.03.013_bb0185","doi-asserted-by":"crossref","first-page":"180","DOI":"10.2174\/156720210792231831","article-title":"Pitavastatin and 4\u2032-hydroxy-3\u2032-methoxyacetophenone HMAP reduce cognitive dysfunction in vascular dementia during experimental diabetes","volume":"7","author":"Sharma","year":"2010","journal-title":"Curr Neurovasc Res"},{"issue":"4","key":"10.1016\/j.pnpbp.2012.03.013_bb0190","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1007\/s00213-011-2164-0","article-title":"Attenuation of vascular dementia by sodium butyrate in streptozotocin diabetic rats","volume":"215","author":"Sharma","year":"2011","journal-title":"Psychopharmacology"},{"issue":"2","key":"10.1016\/j.pnpbp.2012.03.013_bb0195","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.pbb.2011.08.020","article-title":"Behavioral and biochemical investigations to explore pharmacological potential of PPAR-gamma agonists in vascular dementia of diabetic rats","volume":"100","author":"Sharma","year":"2011","journal-title":"Pharmacol Biochem Behav"},{"issue":"2","key":"10.1016\/j.pnpbp.2012.03.013_bb0200","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1177\/0269881107081553","article-title":"Modulation of celecoxib- and streptozotocin-induced experimental dementia of Alzheimer's disease by Pitavastatin and Donepezil","volume":"22","author":"Sharma","year":"2008","journal-title":"J Psychopharmacol"},{"issue":"4","key":"10.1016\/j.pnpbp.2012.03.013_bb0205","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.pbb.2008.02.012","article-title":"Exploitation of HIV protease inhibitor Indinavir as a memory restorative agent in experimental dementia","volume":"89","author":"Sharma","year":"2008","journal-title":"Pharmacol Biochem Behav"},{"issue":"4","key":"10.1016\/j.pnpbp.2012.03.013_bb0210","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.mcn.2010.08.001","article-title":"Hypercholesterolemia in rats impairs the cholinergic system and leads to memory deficits","volume":"45","author":"Ullrich","year":"2010","journal-title":"Mol Cell Neurosci"},{"key":"10.1016\/j.pnpbp.2012.03.013_bb0215","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1161\/01.RES.82.7.810","article-title":"Superoxide anion from the adventitia of the rat thoracic aorta inactivates nitric oxide","volume":"82","author":"Wang","year":"1998","journal-title":"Circ Res"},{"issue":"5","key":"10.1016\/j.pnpbp.2012.03.013_bb0220","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1159\/000322791","article-title":"Challenges of longevity in developed countries vascular prevention of dementia as an immediate clue to tackle an upcoming medical social and economic stretch","volume":"8","author":"Wehling","year":"2011","journal-title":"Neurodegener Dis"},{"issue":"4","key":"10.1016\/j.pnpbp.2012.03.013_bb0225","doi-asserted-by":"crossref","first-page":"R1086","DOI":"10.1152\/ajpregu.00293.2009","article-title":"Induction of hepatic cyclooxygenase-2 by hyperhomocysteinemia via nuclear factor-kappaB activation","volume":"297","author":"Wu","year":"2009","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"issue":"2","key":"10.1016\/j.pnpbp.2012.03.013_bb0230","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.neulet.2011.02.076","article-title":"Methionine diet-induced hyperhomocysteinemia accelerates cerebral aneurysm formation in rats","volume":"494","author":"Xu","year":"2011","journal-title":"Neurosci Lett"},{"issue":"3","key":"10.1016\/j.pnpbp.2012.03.013_bb0235","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.amjcard.2011.03.049","article-title":"Impact of hypertriglyceridemia on endothelial dysfunction during statin\u00b1ezetimibe therapy in patients with coronary heart disease","volume":"108","author":"Yunoki","year":"2011","journal-title":"Am J Cardiol"}],"container-title":["Progress in Neuro-Psychopharmacology and Biological Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S027858461200070X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S027858461200070X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,6,21]],"date-time":"2023-06-21T19:20:42Z","timestamp":1687375242000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S027858461200070X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,8]]},"references-count":47,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,8]]}},"alternative-id":["S027858461200070X"],"URL":"https:\/\/doi.org\/10.1016\/j.pnpbp.2012.03.013","relation":{},"ISSN":["0278-5846"],"issn-type":[{"value":"0278-5846","type":"print"}],"subject":[],"published":{"date-parts":[[2012,8]]}}}