{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:56:38Z","timestamp":1787169398164,"version":"build-2736575974"},"reference-count":197,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2013,4,1]],"date-time":"2013-04-01T00:00:00Z","timestamp":1364774400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Progress in Neuro-Psychopharmacology and Biological Psychiatry"],"published-print":{"date-parts":[[2013,4]]},"DOI":"10.1016\/j.pnpbp.2012.11.007","type":"journal-article","created":{"date-parts":[[2012,11,23]],"date-time":"2012-11-23T05:18:08Z","timestamp":1353647888000},"page":"135-145","source":"Crossref","is-referenced-by-count":95,"special_numbering":"C","title":["Putative neuroprotective agents in neuropsychiatric disorders"],"prefix":"10.1016","volume":"42","author":[{"given":"Seetal","family":"Dodd","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Maes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Anderson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivia M.","family":"Dean","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven","family":"Moylan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Berk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.pnpbp.2012.11.007_bb0005","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1002\/ajmg.b.30338","article-title":"BDNF gene variants and brain morphology in schizophrenia","volume":"141B","author":"Agartz","year":"2006","journal-title":"Am J Med Genet B Neuropsychiatr Genet"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0010","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.tox.2007.11.003","article-title":"Protective effect of minocycline, a semi-synthetic second-generation tetracycline against 3-nitropropionic acid (3-NP)-induced neurotoxicity","volume":"244","author":"Ahuja","year":"2008","journal-title":"Toxicology"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0015","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1111\/j.1440-1681.2007.04853.x","article-title":"In vitro anti-oxidant and DNA protective effects of the novel 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor rosuvastatin","volume":"35","author":"Ajith","year":"2008","journal-title":"Clin Exp Pharmacol Physiol"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0020","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.pnpbp.2012.08.015","article-title":"Dell'Osso B","volume":"42","author":"Altamura","year":"2013","journal-title":"Neurodevelopment and inflammatory patterns in schizophrenia in relation to pathophysiology. Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0025","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1038\/mp.2011.167","article-title":"Decreased nervonic acid levels in erythrocyte membranes predict psychosis in help-seeking ultra-high-risk individuals","volume":"17","author":"Amminger","year":"2012","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0030","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/s11011-012-9307-9","article-title":"Melatonin: an overlooked factor in schizophrenia and in the inhibition of anti-psychotic side effects","volume":"27","author":"Anderson","year":"2012","journal-title":"Metab Brain Dis"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0035","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.pnpbp.2012.06.014","article-title":"Schizophrenia: Linking prenatal infection to cytokines, the tryptophan catabolite (TRYCAT) pathway, NMDA receptor hypofunction, neurodevelopment and neuroprogression","volume":"42","author":"Anderson","year":"2013","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0040","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.pnpbp.2012.07.016","article-title":"Schizophrenia is primed for an increased expression of depression through activation of immuno-inflammatory, oxidative and nitrosative stress, and tryptophan catabolite pathways","volume":"42","author":"Anderson","year":"2013","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0045","doi-asserted-by":"crossref","first-page":"4209","DOI":"10.1097\/00001756-199812210-00038","article-title":"Modafinil prevents glutamate cytotoxicity in cultured cortical neurons","volume":"9","author":"Antonelli","year":"1998","journal-title":"Neuroreport"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0050","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1002\/jnr.10440","article-title":"Expression of brain-derived neurotrophic factor mRNA in rat hippocampus after treatment with antipsychotic drugs","volume":"71","author":"Bai","year":"2003","journal-title":"J Neurosci Res"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0055","doi-asserted-by":"crossref","first-page":"9134","DOI":"10.1523\/JNEUROSCI.22-20-09134.2002","article-title":"The origin and neuronal function of in vivo nonsynaptic glutamate","volume":"22","author":"Baker","year":"2002","journal-title":"J Neurosci"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0060","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1111\/j.1749-6632.2012.06568.x","article-title":"Role of the blood\u2013brain barrier in the evolution of feeding and cognition","volume":"1264","author":"Banks","year":"2012","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0065","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.pscychresns.2011.06.010","article-title":"Amygdala and insula volumes prior to illness onset in bipolar disorder: a magnetic resonance imaging study","volume":"201","author":"Bechdolf","year":"2012","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0070","doi-asserted-by":"crossref","first-page":"570","DOI":"10.2174\/138161212799316163","article-title":"Neuroprotective effects of low-dose lithium in individuals at ultra-high risk for psychosis. A longitudinal MRI\/MRS study","volume":"18","author":"Berger","year":"2012","journal-title":"Curr Pharm Des"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0075","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.jad.2011.06.005","article-title":"The efficacy of N-acetylcysteine as an adjunctive treatment in bipolar depression: an open label trial","volume":"135","author":"Berk","year":"2011","journal-title":"J Affect Disord"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0085","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1016\/j.neubiorev.2010.10.001","article-title":"Pathways underlying neuroprogression in bipolar disorder: focus on inflammation, oxidative stress and neurotrophic factors","volume":"35","author":"Berk","year":"2011","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0080","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1186\/1741-7015-10-91","article-title":"Maintenance N-acetyl cysteine treatment for bipolar disorder: a double-blind randomised placebo controlled trial","volume":"10","author":"Berk","year":"2012","journal-title":"BMC Med"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0090","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.pnpbp.2007.06.031","article-title":"The effect of atypical antipsychotics, perospirone, ziprasidone and quetiapine on microglial activation induced by interferon-gamma","volume":"32","author":"Bian","year":"2008","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0100","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1016\/j.biopsych.2010.01.020","article-title":"Voxelwise meta-analysis of gray matter abnormalities in bipolar disorder","volume":"67","author":"Bora","year":"2010","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0095","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.jad.2011.03.049","article-title":"Gray matter abnormalities in major depressive disorder: a meta-analysis of voxel based morphometry studies","volume":"138","author":"Bora","year":"2011","journal-title":"J Affect Disord"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0105","first-page":"1","article-title":"The effects of gender on grey matter abnormalities in major psychoses: a comparative voxelwise meta-analysis of schizophrenia and bipolar disorder","author":"Bora","year":"2011","journal-title":"Psychol Med"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0110","first-page":"1","article-title":"The effects of gender on grey matter abnormalities in major psychoses: a comparative voxelwise meta-analysis of schizophrenia and bipolar disorder","author":"Bora","year":"2011","journal-title":"Psychol Med"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0115","first-page":"1","article-title":"Meta-analysis of volumetric abnormalities in cortico\u2013striatal\u2013pallidal\u2013thalamic circuits in major depressive disorder","author":"Bora","year":"2011","journal-title":"Psychol Med"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0120","doi-asserted-by":"crossref","first-page":"e160","DOI":"10.1038\/tp.2012.84","article-title":"A longitudinal pilot proton MRS investigation of the manic and euthymic states of bipolar disorder","volume":"2","author":"Brady","year":"2012","journal-title":"Transl Psychiatry"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0125","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.neuroimage.2009.07.070","article-title":"Reduced prefrontal and orbitofrontal gray matter in female adolescents with borderline personality disorder: is it disorder specific?","volume":"49","author":"Brunner","year":"2010","journal-title":"Neuroimage"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0130","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.cbi.2011.12.007","article-title":"Differential protective effects of quercetin, resveratrol, rutin and epigallocatechin gallate against mitochondrial dysfunction induced by indomethacin in Caco-2 cells","volume":"195","author":"Carrasco-Pozo","year":"2012","journal-title":"Chem Biol Interact"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0135","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1111\/j.1471-4159.2005.03457.x","article-title":"Novel targets for valproic acid: up-regulation of melatonin receptors and neurotrophic factors in C6 glioma cells","volume":"95","author":"Castro","year":"2005","journal-title":"J Neurochem"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0140","doi-asserted-by":"crossref","first-page":"8745","DOI":"10.1073\/pnas.96.15.8745","article-title":"Lithium activates the serine\/threonine kinase Akt-1 and suppresses glutamate-induced inhibition of Akt-1 activity in neurons","volume":"96","author":"Chalecka-Franaszek","year":"1999","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0145","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.nbd.2012.03.021","article-title":"Role of the pituitary\u2013adrenal axis in granulocyte-colony stimulating factor-induced neuroprotection against hypoxia-ischemia in neonatal rats","volume":"47","author":"Charles","year":"2012","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0150","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/j.pnpbp.2010.01.020","article-title":"Functional neuroimaging of minocycline's effect in a patient with schizophrenia","volume":"34","author":"Chaves","year":"2010","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0155","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.psychres.2011.01.011","article-title":"Effects of antipsychotics on the serum BDNF levels in schizophrenia","volume":"189","author":"Chen","year":"2011","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0160","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1007\/s11481-012-9382-z","article-title":"Inflammation in patients with schizophrenia: the therapeutic benefits of risperidone plus add-on dextromethorphan","volume":"7","author":"Chen","year":"2012","journal-title":"J Neuroimmune Pharmacol"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0165","doi-asserted-by":"crossref","first-page":"15","DOI":"10.3389\/fnmol.2011.00015","article-title":"GSK-3 as a target for lithium-induced neuroprotection against excitotoxicity in neuronal cultures and animal models of ischemic stroke","volume":"4","author":"Chuang","year":"2011","journal-title":"Front Mol Neurosci"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0170","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.4049\/jimmunol.1000208","article-title":"Paroxetine prevents loss of nigrostriatal dopaminergic neurons by inhibiting brain inflammation and oxidative stress in an experimental model of Parkinson's disease","volume":"185","author":"Chung","year":"2010","journal-title":"J Immunol"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0175","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.ijdevneu.2010.08.007","article-title":"Mitochondrial dysfunction and pathology in bipolar disorder and schizophrenia","volume":"29","author":"Clay","year":"2011","journal-title":"Int J Dev Neurosci"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0180","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1111\/j.1601-183X.2011.00714.x","article-title":"No effect of 5HTTLPR or BDNF Val66Met polymorphism on hippocampal morphology in major depression","volume":"10","author":"Cole","year":"2011","journal-title":"Genes Brain Behav"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0185","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1017\/S1461145710001689","article-title":"3-Hydroxykynurenine and clinical symptoms in first-episode neuroleptic-naive patients with schizophrenia","volume":"14","author":"Condray","year":"2011","journal-title":"Int J Neuropsychopharmacol"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0190","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1016\/j.neuroscience.2006.11.010","article-title":"Role of glutathione in neuroprotective effects of mood stabilizing drugs lithium and valproate","volume":"144","author":"Cui","year":"2007","journal-title":"Neuroscience"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0195","doi-asserted-by":"crossref","first-page":"338","DOI":"10.4049\/jimmunol.181.1.338","article-title":"Lithium prevents and ameliorates experimental autoimmune encephalomyelitis","volume":"181","author":"De Sarno","year":"2008","journal-title":"J Immunol"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0200","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.psychres.2007.05.008","article-title":"Plasma apolipoprotein E is decreased in schizophrenia spectrum and bipolar disorder","volume":"158","author":"Dean","year":"2008","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0205","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1503\/jpn.100057","article-title":"N-acetylcysteine in psychiatry: current therapeutic evidence and potential mechanisms of action","volume":"36","author":"Dean","year":"2011","journal-title":"J Psychiatry Neurosci"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0215","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.neulet.2011.05.027","article-title":"N-acetyl cysteine restores brain glutathione loss in combined 2-cyclohexene-1-one and d-amphetamine-treated rats: relevance to schizophrenia and bipolar disorder","volume":"499","author":"Dean","year":"2011","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0210","doi-asserted-by":"crossref","first-page":"391","DOI":"10.2165\/11632000-000000000-00000","article-title":"Minocycline: therapeutic potential in psychiatry","volume":"26","author":"Dean","year":"2012","journal-title":"CNS Drugs"},{"issue":"7","key":"10.1016\/j.pnpbp.2012.11.007_bb5000","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1007\/s00210-012-0752-0","article-title":"Aspirin metabolites are GPR35 agonists","volume":"385","author":"Deng","year":"2012","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0220","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1111\/j.1471-4159.2005.03319.x","article-title":"Neuroprotection by stem cell factor in rat cortical neurons involves AKT and NFkappaB","volume":"95","author":"Dhandapani","year":"2005","journal-title":"J Neurochem"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0225","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1016\/j.neurobiolaging.2007.01.008","article-title":"Megalin mediates the transport of leptin across the blood\u2013CSF barrier","volume":"29","author":"Dietrich","year":"2008","journal-title":"Neurobiol Aging"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0230","doi-asserted-by":"crossref","first-page":"1955","DOI":"10.1517\/14728220802517901","article-title":"N-acetylcysteine for antioxidant therapy: pharmacology and clinical utility","volume":"8","author":"Dodd","year":"2008","journal-title":"Expert Opin Biol Ther"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0235","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1016\/j.bbi.2006.02.002","article-title":"Cytokines in schizophrenia and the effects of antipsychotic drugs","volume":"20","author":"Drzyzga","year":"2006","journal-title":"Brain Behav Immun"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0240","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1038\/sj.mp.4001442","article-title":"Erythropoietin: a candidate compound for neuroprotection in schizophrenia","volume":"9","author":"Ehrenreich","year":"2004","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0245","doi-asserted-by":"crossref","first-page":"1602","DOI":"10.1007\/s00134-010-1913-6","article-title":"Long-term evaluation of granulocyte-colony stimulating factor on hypoxic\u2013ischemic brain damage in infant rats","volume":"36","author":"Fathali","year":"2010","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0250","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1017\/S1092852900015303","article-title":"Psychiatric comorbidity in 36 adults with mitochondrial cytopathies","volume":"12","author":"Fattal","year":"2007","journal-title":"CNS Spectr"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0255","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/s00011-011-0392-8","article-title":"N-acetylcysteine prevents baker's-yeast-induced inflammation and fever","volume":"61","author":"Ferreira","year":"2012","journal-title":"Inflamm Res"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0260","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.ejpn.2009.07.005","article-title":"Treatment of mitochondrial disorders","volume":"14","author":"Finsterer","year":"2010","journal-title":"Eur J Paediatr Neurol"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0265","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1176\/appi.ajp.2009.09111661","article-title":"Strategies to close the \u201cmortality gap\u201d","volume":"167","author":"Flaum","year":"2010","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0270","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1111\/j.1440-1819.2012.02359.x","article-title":"Treating patients with schizophrenia deficit with erythropoietin?","volume":"66","author":"Fond","year":"2012","journal-title":"Psychiatry Clin Neurosci"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0275","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1097\/RMR.0b013e3181e8f22c","article-title":"Is there evidence of brain white-matter abnormalities in obsessive-compulsive disorder? A narrative review","volume":"20","author":"Fontenelle","year":"2009","journal-title":"Top Magn Reson Imaging"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0280","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1002\/hbm.20412","article-title":"Surface-based morphometry of the anterior cingulate cortex in first episode schizophrenia","volume":"29","author":"Fornito","year":"2008","journal-title":"Hum Brain Mapp"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0285","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1007\/BF02900219","article-title":"Interleukin-6-(IL-6) plasma levels in depression and schizophrenia: comparison between the acute state and after remission","volume":"247","author":"Frommberger","year":"1997","journal-title":"Eur Arch Psychiatry Clin Neurosci"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0290","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1017\/S1461145711000150","article-title":"Modulation of BDNF expression by repeated treatment with the novel antipsychotic lurasidone under basal condition and in response to acute stress","volume":"15","author":"Fumagalli","year":"2012","journal-title":"Int J Neuropsychopharmacol"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0295","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1097\/JCP.0b013e318248b7bb","article-title":"Eicosapentaenoic acid interventions in schizophrenia: meta-analysis of randomized, placebo-controlled studies","volume":"32","author":"Fusar-Poli","year":"2012","journal-title":"J Clin Psychopharmacol"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0300","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1002\/hup.1014","article-title":"Oxidative stress parameters after combined fluoxetine and acetylsalicylic acid therapy in depressive patients","volume":"24","author":"Galecki","year":"2009","journal-title":"Hum Psychopharmacol"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0305","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.bcp.2009.07.028","article-title":"Mitochondria and calcium flux as targets of neuroprotection caused by minocycline in cerebellar granule cells","volume":"79","author":"Garcia-Martinez","year":"2010","journal-title":"Biochem Pharmacol"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0310","series-title":"Cochrane Database Syst Rev, CD002086","article-title":"Minocycline for acne vulgaris: efficacy and safety","author":"Garner","year":"2003"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0315","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1017\/S1461145707007730","article-title":"Compromised myelin integrity during psychosis with repair during remission in drug-responding schizophrenia","volume":"11","author":"Garver","year":"2008","journal-title":"Int J Neuropsychopharmacol"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0320","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1017\/S1461145710000805","article-title":"Decreased levels of glutathione, the major brain antioxidant, in post-mortem prefrontal cortex from patients with psychiatric disorders","volume":"14","author":"Gawryluk","year":"2011","journal-title":"Int J Neuropsychopharmacol"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0325","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1089\/cap.2011.0009","article-title":"Preliminary findings regarding proinflammatory markers and brain-derived neurotrophic factor among adolescents with bipolar spectrum disorders","volume":"21","author":"Goldstein","year":"2011","journal-title":"J Child Adolesc Psychopharmacol"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0330","first-page":"1242","article-title":"Rosuvastatin and metformin decrease inflammation and oxidative stress in patients with hypertension and dyslipidemia","volume":"60","author":"Gomez-Garcia","year":"2007","journal-title":"Rev Esp Cardiol"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0335","doi-asserted-by":"crossref","first-page":"110","DOI":"10.3109\/15622975.2010.507786","article-title":"Association of the brain-derived neurotrophic factor Val66Met polymorphism with hippocampus volumes in drug-free depressed patients","volume":"12","author":"Gonul","year":"2011","journal-title":"World J Biol Psychiatry"},{"issue":"Suppl. 5","key":"10.1016\/j.pnpbp.2012.11.007_bb0340","first-page":"3","article-title":"The use of mood stabilizers as plasticity enhancers in the treatment of neuropsychiatric disorders","volume":"64","author":"Gray","year":"2003","journal-title":"J Clin Psychiatry"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0345","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.jpsychires.2006.01.005","article-title":"Reduced serum BDNF levels in schizophrenic patients on clozapine or typical antipsychotics","volume":"41","author":"Grillo","year":"2007","journal-title":"J Psychiatr Res"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0350","first-page":"786","article-title":"In vitro effects of 5-hydroxytryptophan, indoleamines and leptin on arylalkylamine N-acetyltransferase (AA-NAT) activity in pineal organ of the fish, Clarias gariepinus (Burchell, 1822) during different phases of the breeding cycle","volume":"48","author":"Gupta","year":"2010","journal-title":"Indian J Exp Biol"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0355","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1038\/sj.jcbfm.9600418","article-title":"Marked prevention of ischemic brain injury by Neu 2000, an NMDA antagonist and antioxidant derived from aspirin and sulfasalazine","volume":"27","author":"Gwag","year":"2007","journal-title":"J Cereb Blood Flow Metab"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0360","doi-asserted-by":"crossref","first-page":"2181","DOI":"10.1210\/en.2006-1355","article-title":"Rosuvastatin, a 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor, decreases cardiac oxidative stress and remodeling in Ren2 transgenic rats","volume":"148","author":"Habibi","year":"2007","journal-title":"Endocrinology"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0365","first-page":"43","article-title":"Pharmacological treatment of severe dyslipidaemia in patients with schizophrenia","volume":"22","author":"Hanssens","year":"2007","journal-title":"Int Clin Psychopharmacol"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0370","doi-asserted-by":"crossref","first-page":"470","DOI":"10.2174\/187152709789824633","article-title":"Can the sigma-1 receptor agonist fluvoxamine prevent schizophrenia?","volume":"8","author":"Hashimoto","year":"2009","journal-title":"CNS Neurol Disord Drug Targets"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0375","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.expneurol.2007.03.022","article-title":"Antidepressants inhibit interferon-gamma-induced microglial production of IL-6 and nitric oxide","volume":"206","author":"Hashioka","year":"2007","journal-title":"Exp Neurol"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0380","first-page":"535","article-title":"Lithium enabling use of clozapine in a patient with pre-existing neutropenia","volume":"71","author":"Hodgson","year":"2010","journal-title":"Br J Hosp Med (Lond.)"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0385","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.brainres.2009.07.031","article-title":"Minocycline effects on cerebral edema: relations with inflammatory and oxidative stress markers following traumatic brain injury in mice","volume":"1291","author":"Homsi","year":"2009","journal-title":"Brain Res"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0390","first-page":"336","article-title":"Activities of respiratory chain complexes and citrate synthase influenced by pharmacologically different antidepressants and mood stabilizers","volume":"31","author":"Hroudova","year":"2010","journal-title":"Neuro Endocrinol Lett"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0395","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1007\/s11481-011-9309-0","article-title":"Clozapine protects dopaminergic neurons from inflammation-induced damage by inhibiting microglial overactivation","volume":"7","author":"Hu","year":"2012","journal-title":"J Neuroimmune Pharmacol"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0400","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1254\/jphs.FP0061255","article-title":"Desipramine activated Bcl-2 expression and inhibited lipopolysaccharide-induced apoptosis in hippocampus-derived adult neural stem cells","volume":"104","author":"Huang","year":"2007","journal-title":"J Pharmacol Sci"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0405","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1093\/schbul\/sbm168","article-title":"What happens after the first episode? A review of progressive brain changes in chronically ill patients with schizophrenia","volume":"34","author":"Hulshoff Pol","year":"2008","journal-title":"Schizophr Bull"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0410","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1016\/j.pnpbp.2011.05.011","article-title":"Soluble interleukin-2 receptor levels correlated with positive symptoms during quetiapine treatment in schizophrenia-spectrum disorders","volume":"35","author":"Igue","year":"2011","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0415","doi-asserted-by":"crossref","first-page":"3876","DOI":"10.1073\/pnas.0912531107","article-title":"N-acetylserotonin activates TrkB receptor in a circadian rhythm","volume":"107","author":"Jang","year":"2010","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0420","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.brainres.2009.04.053","article-title":"Fluoxetine attenuates kainic acid-induced neuronal cell death in the mouse hippocampus","volume":"1281","author":"Jin","year":"2009","journal-title":"Brain Res"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0425","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1111\/j.1471-4159.2008.05435.x","article-title":"Inhibitory effects of aripiprazole on interferon-gamma-induced microglial activation via intracellular Ca2+ regulation in vitro","volume":"106","author":"Kato","year":"2008","journal-title":"J Neurochem"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0430","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1124\/mol.111.074120","article-title":"AC927, a sigma receptor ligand, blocks methamphetamine-induced release of dopamine and generation of reactive oxygen species in NG108-15 cells","volume":"81","author":"Kaushal","year":"2012","journal-title":"Mol Pharmacol"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0435","doi-asserted-by":"crossref","first-page":"591","DOI":"10.2147\/OPTH.S11216","article-title":"Minocycline is cytoprotective in human trabecular meshwork cells and optic nerve head astrocytes by increasing expression of XIAP, survivin, and Bcl-2","volume":"4","author":"Kernt","year":"2010","journal-title":"Clin Ophthalmol"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0440","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1007\/978-3-7091-0693-8_44","article-title":"Granulocyte colony-stimulating factor treatment provides neuroprotection in surgically induced brain injured mice","volume":"111","author":"Khatibi","year":"2011","journal-title":"Acta Neurochir Suppl"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0450","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1007\/BF02980066","article-title":"Inhibitory action of minocycline on lipopolysaccharide-induced release of nitric oxide and prostaglandin E2 in BV2 microglial cells","volume":"27","author":"Kim","year":"2004","journal-title":"Arch Pharm Res"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0455","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1097\/FJC.0b013e31804a5e34","article-title":"Rosuvastatin suppresses the inflammatory responses through inhibition of c-Jun N-terminal kinase and Nuclear Factor-kappaB in endothelial cells","volume":"49","author":"Kim","year":"2007","journal-title":"J Cardiovasc Pharmacol"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0445","doi-asserted-by":"crossref","first-page":"647","DOI":"10.5483\/BMBRep.2011.44.10.647","article-title":"Imipramine enhances neuroprotective effect of PEP-1-Catalase against ischemic neuronal damage","volume":"44","author":"Kim","year":"2011","journal-title":"BMB Rep"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0460","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1111\/j.1399-5618.2007.00444.x","article-title":"An imbalance in the production of IL-1beta and IL-6 by monocytes of bipolar patients: restoration by lithium treatment","volume":"9","author":"Knijff","year":"2007","journal-title":"Bipolar Disord"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0465","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.ejphar.2010.10.064","article-title":"Aripiprazole protects cortical neurons from glutamate toxicity","volume":"651","author":"Koprivica","year":"2011","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0470","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1016\/j.pnpbp.2010.08.026","article-title":"In animal models, psychosocial stress-induced (neuro)inflammation, apoptosis and reduced neurogenesis are associated to the onset of depression","volume":"35","author":"Kubera","year":"2011","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0475","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1097\/JCP.0b013e318234ee84","article-title":"Polymorphisms of INSIG2, MC4R, and LEP are associated with obesity- and metabolic-related traits in schizophrenic patients","volume":"31","author":"Kuo","year":"2011","journal-title":"J Clin Psychopharmacol"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0480","first-page":"41","article-title":"The HMG-CoA reductase inhibitor simvastatin inhibits IFN-gamma induced MHC class II expression in human vascular endothelial cells","volume":"131","author":"Kwak","year":"2001","journal-title":"Swiss Med Wkly"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0485","doi-asserted-by":"crossref","first-page":"1784","DOI":"10.1093\/emboj\/19.8.1784","article-title":"Polyunsaturated fatty acids are potent neuroprotectors","volume":"19","author":"Lauritzen","year":"2000","journal-title":"EMBO J"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0490","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1176\/appi.neuropsych.22.2.130","article-title":"Psychopharmacological neuroprotection in neurodegenerative disease: heuristic clinical applications","volume":"22","author":"Lauterbach","year":"2010","journal-title":"J Neuropsychiatry Clin Neurosci"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0495","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.taap.2012.06.005","article-title":"Reactive oxygen species regulated mitochondria-mediated apoptosis in PC12 cells exposed to chlorpyrifos","volume":"263","author":"Lee","year":"2012","journal-title":"Toxicol Appl Pharmacol"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0500","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1016\/j.neubiorev.2011.12.005","article-title":"Mechanistic explanations how cell-mediated immune activation, inflammation and oxidative and nitrosative stress pathways and their sequels and concomitants play a role in the pathophysiology of unipolar depression","volume":"36","author":"Leonard","year":"2012","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0505","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1176\/ajp.153.4.582b","article-title":"Possible antidepressant effect of minocycline","volume":"153","author":"Levine","year":"1996","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0510","doi-asserted-by":"crossref","first-page":"138","DOI":"10.4088\/JCP.08m04666yel","article-title":"A double-blind, randomized study of minocycline for the treatment of negative and cognitive symptoms in early-phase schizophrenia","volume":"71","author":"Levkovitz","year":"2010","journal-title":"J Clin Psychiatry"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0515","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1002\/jnr.21899","article-title":"Fluoxetine affords robust neuroprotection in the postischemic brain via its anti-inflammatory effect","volume":"87","author":"Lim","year":"2009","journal-title":"J Neurosci Res"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0520","doi-asserted-by":"crossref","first-page":"2945","DOI":"10.1093\/eurheartj\/ehl277","article-title":"Rapid immunomodulation by rosuvastatin in patients with acute coronary syndrome","volume":"27","author":"Link","year":"2006","journal-title":"Eur Heart J"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0525","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0033-3182(90)72212-8","article-title":"Somatization and depression","volume":"31","author":"Lipowski","year":"1990","journal-title":"Psychosomatics"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0535","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.brainres.2004.03.018","article-title":"Olanzapine produces trophic effects in vitro and stimulates phosphorylation of Akt\/PKB, ERK1\/2, and the mitogen-activated protein kinase p38","volume":"1011","author":"Lu","year":"2004","journal-title":"Brain Res"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0530","first-page":"1251","article-title":"Effect of clozapine and risperidone on serum cytokine levels in patients with first-episode paranoid schizophrenia","volume":"24","author":"Lu","year":"2004","journal-title":"Di Yi Jun Yi Da Xue Xue Bao"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0540","doi-asserted-by":"crossref","first-page":"28656","DOI":"10.1074\/jbc.M112.356584","article-title":"The antiepileptic drug valproic Acid restores T cell homeostasis and ameliorates pathogenesis of experimental autoimmune encephalomyelitis","volume":"287","author":"Lv","year":"2012","journal-title":"J Biol Chem"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0575","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.psychres.2011.09.029","article-title":"Diagnostic classifications in depression and somatization should include biomarkers, such as disorders in the tryptophan catabolite (TRYCAT) pathway","volume":"196","author":"Maes","year":"2012","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0570","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1111\/j.1600-0447.1994.tb01527.x","article-title":"Immune-inflammatory markers in schizophrenia: comparison to normal controls and effects of clozapine","volume":"89","author":"Maes","year":"1994","journal-title":"Acta Psychiatr Scand"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0550","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/S0920-9964(97)00057-1","article-title":"In vivo immunomodulatory effects of clozapine in schizophrenia","volume":"26","author":"Maes","year":"1997","journal-title":"Schizophr Res"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0555","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0165-1781(96)02915-0","article-title":"Acute phase proteins in schizophrenia, mania and major depression: modulation by psychotropic drugs","volume":"66","author":"Maes","year":"1997","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0580","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1007\/s002130050965","article-title":"In vitro immunoregulatory effects of lithium in healthy volunteers","volume":"143","author":"Maes","year":"1999","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0545","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0920-9964(00)00094-3","article-title":"Increased serum interleukin-8 and interleukin-10 in schizophrenic patients resistant to treatment with neuroleptics and the stimulatory effects of clozapine on serum leukemia inhibitory factor receptor","volume":"54","author":"Maes","year":"2002","journal-title":"Schizophr Res"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0565","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1016\/j.pnpbp.2010.05.004","article-title":"A review on the oxidative and nitrosative stress (O&NS) pathways in major depression and their possible contribution to the (neuro)degenerative processes in that illness","volume":"35","author":"Maes","year":"2011","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0560","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/s10787-011-0111-7","article-title":"New drug targets in depression: inflammatory, cell-mediated immune, oxidative and nitrosative stress, mitochondrial, antioxidant, and neuroprogressive pathways. And new drug candidates\u2013Nrf2 activators and GSK-3 inhibitors","volume":"20","author":"Maes","year":"2012","journal-title":"Inflammopharmacology"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0585","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1034\/j.1600-079X.2002.02113.x","article-title":"Several antioxidant pathways are involved in astrocyte protection by melatonin","volume":"33","author":"Martin","year":"2002","journal-title":"J Pineal Res"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0590","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1111\/j.1399-5618.2009.00729.x","article-title":"Lithium-induced enhancement of mitochondrial oxidative phosphorylation in human brain tissue","volume":"11","author":"Maurer","year":"2009","journal-title":"Bipolar Disord"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0595","doi-asserted-by":"crossref","first-page":"319","DOI":"10.5414\/CPP45319","article-title":"Rosuvastatin reduces interleukin-6-induced expression of C-reactive protein in human hepatocytes in a STAT3- and C\/EBP-dependent fashion","volume":"45","author":"Mayer","year":"2007","journal-title":"Int J Clin Pharmacol Ther"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0600","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/0920-9964(94)00067-I","article-title":"Posterior superior temporal gyrus in schizophrenia: grey matter changes and clinical correlates","volume":"16","author":"Menon","year":"1995","journal-title":"Schizophr Res"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0605","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/j.biopsych.2011.04.013","article-title":"Meta-analysis of cytokine alterations in schizophrenia: clinical status and antipsychotic effects","volume":"70","author":"Miller","year":"2011","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0610","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1007\/s00213-011-2511-1","article-title":"Erythropoietin: a candidate treatment for mood symptoms and memory dysfunction in depression","volume":"219","author":"Miskowiak","year":"2012","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0615","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1177\/1359786810382056","article-title":"Do deficits in cardiac care influence high mortality rates in schizophrenia? A systematic review and pooled analysis","volume":"24","author":"Mitchell","year":"2010","journal-title":"J Psychopharmacol"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0625","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/j.pnpbp.2006.08.013","article-title":"Possible antipsychotic effects of minocycline in patients with schizophrenia","volume":"31","author":"Miyaoka","year":"2007","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0630","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1097\/WNF.0b013e3181593d45","article-title":"Minocycline as adjunctive therapy for schizophrenia: an open-label study","volume":"31","author":"Miyaoka","year":"2008","journal-title":"Clin Neuropharmacol"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0620","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.pnpbp.2012.02.002","article-title":"Minocycline as adjunctive therapy for patients with unipolar psychotic depression: an open-label study","volume":"37","author":"Miyaoka","year":"2012","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0635","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1017\/S0033291709992297","article-title":"A systematic review of the effects of antipsychotic drugs on brain volume","volume":"40","author":"Moncrieff","year":"2010","journal-title":"Psychol Med"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0640","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.pnpbp.2011.12.002","article-title":"Neuroinflammation in schizophrenia especially focused on the role of microglia","volume":"42","author":"Monji","year":"2013","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0645","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1159\/000119377","article-title":"Decreased nocturnal secretion of melatonin in drug-free schizophrenics: no change after subchronic treatment with antipsychotics","volume":"36","author":"Monteleone","year":"1997","journal-title":"Neuropsychobiology"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0650","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0006-3223(00)00252-3","article-title":"Lithium increases N-acetyl-aspartate in the human brain: in vivo evidence in support of bcl-2's neurotrophic effects?","volume":"48","author":"Moore","year":"2000","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0655","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1007\/s00702-011-0763-x","article-title":"Kynurenic acid: a metabolite with multiple actions and multiple targets in brain and periphery","volume":"119","author":"Moroni","year":"2012","journal-title":"J Neural Transm"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0660","doi-asserted-by":"crossref","DOI":"10.1038\/mp.2012.33","article-title":"The neuroprogressive nature of major depressive disorder: pathways to disease evolution and resistance, and therapeutic implications","author":"Moylan","year":"2012","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0665","doi-asserted-by":"crossref","first-page":"130","DOI":"10.2174\/138161211795049552","article-title":"Kynurenine pathway in schizophrenia: pathophysiological and therapeutic aspects","volume":"17","author":"Muller","year":"2011","journal-title":"Curr Pharm Des"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0670","doi-asserted-by":"crossref","first-page":"1576","DOI":"10.1016\/j.bbi.2011.05.005","article-title":"Reversal of imbalance between kynurenic acid and 3-hydroxykynurenine by antipsychotics in medication-naive and medication-free schizophrenic patients","volume":"25","author":"Myint","year":"2011","journal-title":"Brain Behav Immun"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0675","unstructured":"Nierenberg AA, Kansky C, Brennan BP, Shelton RC, Perlis R, Iosifescu DV. Mitochondrial modulators for bipolar disorder: A pathophysiologically informed paradigm for new drug development. Aust N Z J Psychiatry in press, [Electronic publication ahead of print]."},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0680","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.1038\/emboj.2009.57","article-title":"The mechano-activated K+ channels TRAAK and TREK-1 control both warm and cold perception","volume":"28","author":"Noel","year":"2009","journal-title":"EMBO J"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0685","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1007\/s12640-009-9120-3","article-title":"A study on the mechanisms by which minocycline protects against MDMA (\u2018ecstasy\u2019)-induced neurotoxicity of 5-HT cortical neurons","volume":"18","author":"Orio","year":"2010","journal-title":"Neurotox Res"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0690","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.ejphar.2011.04.014","article-title":"Minocycline attenuates the development of diabetic neuropathic pain: possible anti-inflammatory and anti-oxidant mechanisms","volume":"661","author":"Pabreja","year":"2011","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0695","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1016\/j.intimp.2005.10.004","article-title":"Antipsychotic treatment may alter T-helper (TH) 2 arm cytokines","volume":"6","author":"Pae","year":"2006","journal-title":"Int Immunopharmacol"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0700","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0140-6736(03)12323-9","article-title":"Neuroanatomical abnormalities before and after onset of psychosis: a cross-sectional and longitudinal MRI comparison","volume":"361","author":"Pantelis","year":"2003","journal-title":"Lancet"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0705","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.euroneuro.2008.12.012","article-title":"Differential effects of aripiprazole and haloperidol on BDNF-mediated signal changes in SH-SY5Y cells","volume":"19","author":"Park","year":"2009","journal-title":"Eur Neuropsychopharmacol"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0710","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.neures.2011.08.010","article-title":"Effects of antipsychotic drugs on BDNF, GSK-3beta, and beta-catenin expression in rats subjected to immobilization stress","volume":"71","author":"Park","year":"2011","journal-title":"Neurosci Res"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0715","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.jad.2007.07.024","article-title":"Leptin in depressed women: cross-sectional and longitudinal data from an epidemiologic study","volume":"107","author":"Pasco","year":"2008","journal-title":"J Affect Disord"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0720","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1084\/jem.20040566","article-title":"15-epi-lipoxin A4-mediated induction of nitric oxide explains how aspirin inhibits acute inflammation","volume":"200","author":"Paul-Clark","year":"2004","journal-title":"J Exp Med"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0725","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.neulet.2011.01.039","article-title":"Serum brain-derived neurotrophic factor and clozapine daily dose in patients with schizophrenia: a positive correlation","volume":"491","author":"Pedrini","year":"2011","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0730","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.euroneuro.2007.05.002","article-title":"Neuroprotection by Imipramine against lipopolysaccharide-induced apoptosis in hippocampus-derived neural stem cells mediated by activation of BDNF and the MAPK pathway","volume":"18","author":"Peng","year":"2008","journal-title":"Eur Neuropsychopharmacol"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0735","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.expneurol.2007.10.015","article-title":"The antidepressant sertraline improves the phenotype, promotes neurogenesis and increases BDNF levels in the R6\/2 Huntington's disease mouse model","volume":"210","author":"Peng","year":"2008","journal-title":"Exp Neurol"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0740","unstructured":"Politi P, RocchettiM, Emanuele E, RondanelliM, Barale F. Randomized Placebo-Controlled Trials of Omega-3 Polyunsaturated Fatty Acids in Psychiatric Disorders: a Review of Current Literature. Curr Drug Discov Technol in press, [Electronic publication ahead of print]."},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0745","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/S0022-3565(24)36399-2","article-title":"Neuroleptic-induced mitochondrial enzyme alterations in the rat brain","volume":"280","author":"Prince","year":"1997","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0750","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1038\/aps.2009.72","article-title":"Neuron differentiation and neuritogenesis stimulated by N-acetylcysteine (NAC)","volume":"30","author":"Qian","year":"2009","journal-title":"Acta Pharmacol Sin"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0755","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1038\/sj.npp.1301093","article-title":"Olanzapine-induced weight gain and increased visceral adiposity is blocked by melatonin replacement therapy in rats","volume":"32","author":"Raskind","year":"2007","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0760","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1111\/j.1600-079X.2010.00798.x","article-title":"Melatonin effect on plasma adiponectin, leptin, insulin, glucose, triglycerides and cholesterol in normal and high fat-fed rats","volume":"49","author":"Rios-Lugo","year":"2010","journal-title":"J Pineal Res"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0765","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.4088\/JCP.v64n1114","article-title":"The attribution of somatization in schizophrenia patients: a naturalistic follow-up study","volume":"64","author":"Ritsner","year":"2003","journal-title":"J Clin Psychiatry"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0770","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.4088\/JCP.09l05805blu","article-title":"Minocycline augmentation of pharmacotherapy in obsessive-compulsive disorder: an open-label trial","volume":"71","author":"Rodriguez","year":"2010","journal-title":"J Clin Psychiatry"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0775","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.1001\/jama.279.20.1643","article-title":"Antiatherothrombotic properties of statins: implications for cardiovascular event reduction","volume":"279","author":"Rosenson","year":"1998","journal-title":"JAMA"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0780","doi-asserted-by":"crossref","first-page":"1617","DOI":"10.1016\/j.pnpbp.2008.04.017","article-title":"Neurodevelopmental basis of bipolar disorder: a critical appraisal","volume":"32","author":"Sanches","year":"2008","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0785","doi-asserted-by":"crossref","first-page":"81","DOI":"10.4088\/JCP.10r06710","article-title":"Omega-3 for bipolar disorder: meta-analyses of use in mania and bipolar depression","volume":"73","author":"Sarris","year":"2012","journal-title":"J Clin Psychiatry"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0795","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/S0304-3940(02)00615-8","article-title":"Increased gray matter volume in lithium-treated bipolar disorder patients","volume":"329","author":"Sassi","year":"2002","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0790","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.biopsych.2004.07.005","article-title":"Reduced left anterior cingulate volumes in untreated bipolar patients","volume":"56","author":"Sassi","year":"2004","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0800","doi-asserted-by":"crossref","first-page":"4991","DOI":"10.1074\/jbc.M110.169565","article-title":"Neuroprotection by minocycline caused by direct and specific scavenging of peroxynitrite","volume":"286","author":"Schildknecht","year":"2010","journal-title":"J Biol Chem"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0805","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.atherosclerosis.2007.11.016","article-title":"Rosuvastatin protects against oxidative stress and DNA damage in vitro via upregulation of glutathione synthesis","volume":"199","author":"Schupp","year":"2008","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0810","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1038\/aps.2010.211","article-title":"Combined prostaglandin E1 and lithium exert potent neuroprotection in a rat model of cerebral ischemia","volume":"32","author":"Sheng","year":"2011","journal-title":"Acta Pharmacol Sin"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0815","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1080\/10715760701885380","article-title":"Anti-hypertensive effects of Rosuvastatin are associated with decreased inflammation and oxidative stress markers in hypertensive rats","volume":"42","author":"Sicard","year":"2008","journal-title":"Free Radic Res"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0820","doi-asserted-by":"crossref","first-page":"307","DOI":"10.3233\/JAD-2010-101179","article-title":"Statins as neuroprotectants: a comparative in vitro study of lipophilicity, blood\u2013brain-barrier penetration, lowering of brain cholesterol, and decrease of neuron cell death","volume":"23","author":"Sierra","year":"2011","journal-title":"J Alzheimers Dis"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0825","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1016\/j.neuroscience.2007.12.026","article-title":"Lithium blocks stress-induced changes in depressive-like behavior and hippocampal cell fate: the role of glycogen-synthase-kinase-3beta","volume":"152","author":"Silva","year":"2008","journal-title":"Neuroscience"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0830","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1161\/01.ATV.0000157145.98200.55","article-title":"Rosuvastatin, but not simvastatin, provides end-organ protection in stroke-prone rats by antiinflammatory effects","volume":"25","author":"Sironi","year":"2005","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0835","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.pbb.2008.11.004","article-title":"Minocycline reduced craving for cigarettes but did not affect smoking or intravenous nicotine responses in humans","volume":"92","author":"Sofuoglu","year":"2009","journal-title":"Pharmacol Biochem Behav"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0840","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0920-9964(99)00116-4","article-title":"Immunosuppressive effects of clozapine and haloperidol: enhanced production of the interleukin-1 receptor antagonist","volume":"42","author":"Song","year":"2000","journal-title":"Schizophr Res"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0845","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.1176\/appi.ajp.159.11.1841","article-title":"Ventricular and periventricular structural volumes in first- versus multiple-episode bipolar disorder","volume":"159","author":"Strakowski","year":"2002","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0850","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.schres.2008.12.029","article-title":"Follow-up MRI study of the insular cortex in first-episode psychosis and chronic schizophrenia","volume":"108","author":"Takahashi","year":"2009","journal-title":"Schizophr Res"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0860","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/j.euroneuro.2007.03.010","article-title":"Immunomodulatory effect of selective serotonin reuptake inhibitors (SSRIs) on human T lymphocyte function and gene expression","volume":"17","author":"Taler","year":"2007","journal-title":"Eur Neuropsychopharmacol"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0855","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1016\/j.intimp.2007.12.003","article-title":"Evidence for an inhibitory immunomodulatory effect of selected antidepressants on rat splenocytes: possible relevance to depression and hyperactive-immune disorders","volume":"8","author":"Taler","year":"2008","journal-title":"Int Immunopharmacol"},{"issue":"559","key":"10.1016\/j.pnpbp.2012.11.007_bb0865","first-page":"e1","article-title":"A case of methamphetamine use disorder treated with the antibiotic drug minocycline","volume":"32","author":"Tanibuchi","year":"2009","journal-title":"Gen Hosp Psychiatry"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0870","doi-asserted-by":"crossref","unstructured":"Tasdemir S, Parlakpinar H, Vardi N, Kaya E, Acet A. Effect of endogen-exogenous melatonin and erythropoietin on dinitrobenzene sulfonic acid-induced colitis. Fundam Clin Pharmacol in press. http:\/\/dx.doi.org\/10.1111\/j.1472-8206.2011.01016.x. [Electronic publication ahead of print].","DOI":"10.1111\/j.1472-8206.2011.01016.x"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0875","doi-asserted-by":"crossref","first-page":"e38469","DOI":"10.1371\/journal.pone.0038469","article-title":"Bipolar disorder, brain-derived neurotrophic factor (BDNF) Val66Met polymorphism and brain morphology","volume":"7","author":"Teh","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0880","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.4088\/JCP.08m04754blu","article-title":"Reduced anterior cingulate and orbitofrontal volumes in child abuse-related complex PTSD","volume":"71","author":"Thomaes","year":"2010","journal-title":"J Clin Psychiatry"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0885","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/S0049-3848(03)00379-7","article-title":"The mechanism of action of aspirin","volume":"110","author":"Vane","year":"2003","journal-title":"Thromb Res"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0890","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/1471-2210-9-10","article-title":"Psychotropic drugs up-regulate the expression of cholesterol transport proteins including ApoE in cultured human CNS- and liver cells","volume":"9","author":"Vik-Mo","year":"2009","journal-title":"BMC Pharmacol"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0895","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1111\/j.1471-4159.2005.03033.x","article-title":"Erythropoietin protects primary hippocampal neurons increasing the expression of brain-derived neurotrophic factor","volume":"93","author":"Viviani","year":"2005","journal-title":"J Neurochem"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0900","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1002\/jnr.10281","article-title":"Atypical neuroleptics stimulate neurogenesis in adult rat brain","volume":"69","author":"Wakade","year":"2002","journal-title":"J Neurosci Res"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0910","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1186\/1742-2094-8-95","article-title":"Aspirin-triggered lipoxin A4 attenuates LPS-induced pro-inflammatory responses by inhibiting activation of NF-kappaB and MAPKs in BV-2 microglial cells","volume":"8","author":"Wang","year":"2011","journal-title":"J Neuroinflammation"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0905","doi-asserted-by":"crossref","first-page":"848","DOI":"10.3892\/mmr.2012.997","article-title":"Therapeutic effect of mesenchymal stem cells in rats with intracerebral hemorrhage: reduced apoptosis and enhanced neuroprotection","volume":"6","author":"Wang","year":"2012","journal-title":"Mol Med Report"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0915","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1093\/schbul\/sbq002","article-title":"Cortical kynurenine pathway metabolism: a novel target for cognitive enhancement in Schizophrenia","volume":"36","author":"Wonodi","year":"2010","journal-title":"Schizophr Bull"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0920","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/0920-9964(91)90073-Z","article-title":"Early intervention with neuroleptics may decrease the long-term morbidity of schizophrenia","volume":"5","author":"Wyatt","year":"1991","journal-title":"Schizophr Res"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0925","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1007\/s00213-011-2291-7","article-title":"Neuroprotection of paliperidone on SH-SY5Y cells against beta-amyloid peptide(25\u201335), N-methyl-4-phenylpyridinium ion, and hydrogen peroxide-induced cell death","volume":"217","author":"Yang","year":"2011","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0930","doi-asserted-by":"crossref","first-page":"e42676","DOI":"10.1371\/journal.pone.0042676","article-title":"Decreased serum levels of mature brain-derived neurotrophic factor (BDNF), but not its precursor proBDNF, in patients with major depressive disorder","volume":"7","author":"Yoshida","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0935","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1176\/appi.neuropsych.20.1.107-a","article-title":"The neuroprotective effect of olanzapine","volume":"20","author":"Yulug","year":"2008","journal-title":"J Neuropsychiatry Clin Neurosci"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0940","doi-asserted-by":"crossref","first-page":"2341","DOI":"10.1161\/STROKEAHA.110.586081","article-title":"Omega-3 polyunsaturated fatty acid supplementation confers long-term neuroprotection against neonatal hypoxic\u2013ischemic brain injury through anti-inflammatory actions","volume":"41","author":"Zhang","year":"2010","journal-title":"Stroke"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0945","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1007\/s00702-011-0713-7","article-title":"The effect of intrathecal administration of glial activation inhibitors on dorsal horn BDNF overexpression and hind paw mechanical allodynia in spinal nerve ligated rats","volume":"119","author":"Zhang","year":"2012","journal-title":"J Neural Transm"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0950","doi-asserted-by":"crossref","first-page":"2804","DOI":"10.1161\/STROKEAHA.107.486217","article-title":"Beneficial effects of hematopoietic growth factor therapy in chronic ischemic stroke in rats","volume":"38","author":"Zhao","year":"2007","journal-title":"Stroke"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0955","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/j.expneurol.2006.12.001","article-title":"Hematopoietic growth factors pass through the blood\u2013brain barrier in intact rats","volume":"204","author":"Zhao","year":"2007","journal-title":"Exp Neurol"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0960","doi-asserted-by":"crossref","first-page":"2584","DOI":"10.1161\/STROKEAHA.106.476457","article-title":"Brain repair by hematopoietic growth factors in a rat model of stroke","volume":"38","author":"Zhao","year":"2007","journal-title":"Stroke"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0965","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.neuint.2007.04.005","article-title":"Hydrogen peroxide attenuates insulin-like growth factor-1 neuroprotective effect, prevented by minocycline","volume":"51","author":"Zhong","year":"2007","journal-title":"Neurochem Int"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0970","doi-asserted-by":"crossref","first-page":"4493","DOI":"10.1523\/JNEUROSCI.4530-04.2005","article-title":"The anti-apoptotic, glucocorticoid receptor cochaperone protein BAG-1 is a long-term target for the actions of mood stabilizers","volume":"25","author":"Zhou","year":"2005","journal-title":"J Neurosci"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0975","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1111\/j.1460-9568.2008.06594.x","article-title":"Astrocyte-derived kynurenic acid modulates basal and evoked cortical acetylcholine release","volume":"29","author":"Zmarowski","year":"2009","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.pnpbp.2012.11.007_bb0980","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1590\/S1516-44462012000200009","article-title":"Energy metabolism, leptin, and biochemical parameters are altered in rats subjected to the chronic administration of olanzapine","volume":"34","author":"Zugno","year":"2012","journal-title":"Rev Bras Psiquiatr"}],"container-title":["Progress in Neuro-Psychopharmacology and Biological Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278584612002898?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278584612002898?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,4,22]],"date-time":"2025-04-22T12:41:19Z","timestamp":1745325679000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0278584612002898"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,4]]},"references-count":197,"alternative-id":["S0278584612002898"],"URL":"https:\/\/doi.org\/10.1016\/j.pnpbp.2012.11.007","relation":{},"ISSN":["0278-5846"],"issn-type":[{"value":"0278-5846","type":"print"}],"subject":[],"published":{"date-parts":[[2013,4]]}}}