{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T23:56:49Z","timestamp":1792108609543,"version":"4.4.0"},"reference-count":161,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2013,7,1]],"date-time":"2013-07-01T00:00:00Z","timestamp":1372636800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000738","name":"Veterans Affairs Department","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100000738","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Progress in Neuro-Psychopharmacology and Biological Psychiatry"],"published-print":{"date-parts":[[2013,7]]},"DOI":"10.1016\/j.pnpbp.2013.01.001","type":"journal-article","created":{"date-parts":[[2013,1,12]],"date-time":"2013-01-12T06:42:29Z","timestamp":1357972949000},"page":"1-16","source":"Crossref","is-referenced-by-count":59,"special_numbering":"C","title":["Differential effectiveness of tianeptine, clonidine and amitriptyline in blocking traumatic memory expression, anxiety and hypertension in an animal model of PTSD"],"prefix":"10.1016","volume":"44","author":[{"given":"Phillip R.","family":"Zoladz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monika","family":"Fleshner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David M.","family":"Diamond","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.pnpbp.2013.01.001_bb0005","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/0031-9384(93)90050-P","article-title":"Lasting effects on rodent anxiety of a single exposure to a cat","volume":"54","author":"Adamec","year":"1993","journal-title":"Physiol Behav"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0010","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/S0022-3956(02)00058-4","article-title":"Psychopharmacological treatment in PTSD: a critical review","volume":"36","author":"Albucher","year":"2002","journal-title":"J Psychiatr Res"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0015","series-title":"Diagnostic and statistical manual of mental disorders: DSM-IV","author":"American Psychiatric Association","year":"1994"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0020","doi-asserted-by":"crossref","first-page":"383","DOI":"10.2165\/00003495-200464040-00004","article-title":"SSRIs versus non-SSRIs in post-traumatic stress disorder: an update with recommendations","volume":"64","author":"Asnis","year":"2004","journal-title":"Drugs"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0025","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S0306-4522(96)00435-6","article-title":"Temporal dynamics of glutamate efflux in the prefrontal cortex and in the hippocampus following repeated stress: effects of pretreatment with saline or diazepam","volume":"77","author":"Bagley","year":"1997","journal-title":"Neuroscience"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0030","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1101\/lm.46102","article-title":"Effects of stress and hippocampal NMDA receptor antagonism on recognition memory in rats","volume":"9","author":"Baker","year":"2002","journal-title":"Learn Mem"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0035","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1007\/BF02246271","article-title":"A double-blind, randomized, placebo-controlled, multi-center study of brofaromine in the treatment of post-traumatic stress disorder","volume":"122","author":"Baker","year":"1995","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0040","first-page":"64","article-title":"Comparison of the cardiovascular effects of amineptine with those of amitriptyline and imipramine in anaesthetized rats","volume":"309","author":"Balcioglu","year":"1991","journal-title":"Arch Int Pharmacodyn Ther"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0045","first-page":"25","article-title":"Regulation of corticosteroid receptor gene expression in depression and antidepressant action","volume":"24","author":"Barden","year":"1999","journal-title":"J Psychiatry Neurosci"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0050","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/0306-4522(95)00084-V","article-title":"Stress-induced changes in messenger RNA levels of N-methyl-d-aspartate and AMPA receptor subunits in selected regions of the rat hippocampus and hypothalamus","volume":"66","author":"Bartanusz","year":"1995","journal-title":"Neuroscience"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0055","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1192\/apt.bp.105.001909","article-title":"Pharmacological treatment of post-traumatic stress disorder","volume":"13","author":"Bisson","year":"2007","journal-title":"Adv Psychiatr Treat"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0060","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1111\/j.1440-1681.1991.tb01385.x","article-title":"Effects of clonidine on blood-pressure and heart-rate responses to an emotional-stress in the Rat \u2014 a spectral study","volume":"18","author":"Blanc","year":"1991","journal-title":"Clin Exp Pharmacol Physiol"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0065","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1007\/BF00181937","article-title":"The effects of chronic antidepressant treatment in an animal model of anxiety","volume":"95","author":"Bodnoff","year":"1988","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0070","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1097\/01.pra.0000265763.79753.c1","article-title":"Pharmacologic reduction of CNS noradrenergic activity in PTSD: the case for clonidine and prazosin","volume":"13","author":"Boehnlein","year":"2007","journal-title":"J Psychiatr Pract"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0075","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1196\/annals.1314.011","article-title":"Posttraumatic stress disorder and physical illness: results from clinical and epidemiologic studies","volume":"1032","author":"Boscarino","year":"2004","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0080","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1097\/PSY.0b013e3181d9a80c","article-title":"A twin study of the association between PTSD symptoms and rheumatoid arthritis","volume":"72","author":"Boscarino","year":"2010","journal-title":"Psychosom Med"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0085","doi-asserted-by":"crossref","first-page":"1837","DOI":"10.1001\/jama.283.14.1837","article-title":"Efficacy and safety of sertraline treatment of posttraumatic stress disorder: a randomized controlled trial","volume":"283","author":"Brady","year":"2000","journal-title":"JAMA"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0090","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1037\/0022-006X.68.5.748","article-title":"Meta-analysis of risk factors for posttraumatic stress disorder in trauma-exposed adults","volume":"68","author":"Brewin","year":"2000","journal-title":"J Consult Clin Psychol"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0095","doi-asserted-by":"crossref","first-page":"29","DOI":"10.2174\/157488906775245327","article-title":"Tianeptine: a novel atypical antidepressant that may provide new insights into the biomolecular basis of depression","volume":"1","author":"Brink","year":"2006","journal-title":"Recent Pat CNS Drug Discov"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0100","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1097\/01.CHI.0000052509.98293.97","article-title":"Prazosin in PTSD","volume":"42","author":"Brkanac","year":"2003","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0105","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1177\/0269881106074062","article-title":"A single dose of citalopram increases fear recognition in healthy subjects","volume":"21","author":"Browning","year":"2007","journal-title":"J Psychopharmacol"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0110","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1097\/JCP.0b013e318222f360","article-title":"Trauma reactivation under the influence of propranolol decreases posttraumatic stress symptoms and disorder: 3 open-label trials","volume":"31","author":"Brunet","year":"2011","journal-title":"J Clin Psychopharmacol"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0115","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1097\/00006842-200107000-00011","article-title":"A meta-analytic examination of basal cardiovascular activity in posttraumatic stress disorder","volume":"63","author":"Buckley","year":"2001","journal-title":"Psychosom Med"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0120","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1016\/j.biopsych.2004.02.029","article-title":"The selective serotonin reuptake inhibitor citalopram increases fear after acute treatment but reduces fear with chronic treatment: A comparison with tianeptine","volume":"55","author":"Burghardt","year":"2004","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0125","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1016\/j.biopsych.2006.11.023","article-title":"Acute selective serotonin reuptake inhibitors increase conditioned fear expression: blockade with a 5-HT(2C) receptor antagonist","volume":"62","author":"Burghardt","year":"2007","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0130","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/S0033-3182(84)72977-X","article-title":"Treatment of post-traumatic stress disorder with imipramine","volume":"25","author":"Burstein","year":"1984","journal-title":"Psychosomatics"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0135","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.euroneuro.2007.04.004","article-title":"Pre-training administration of tianeptine, but not propranolol, protects hippocampus-dependent memory from being impaired by predator stress","volume":"18","author":"Campbell","year":"2008","journal-title":"Eur Neuropsychopharmacol"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0140","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1007\/s002130000595","article-title":"Chronic treatment with the atypical antidepressant tianeptine attenuates sickness behavior induced by peripheral but not central lipopolysaccharide and interleukin-1 beta in the rat","volume":"154","author":"Castanon","year":"2001","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0145","doi-asserted-by":"crossref","first-page":"179","DOI":"10.5455\/bcp.20110627111141","article-title":"Efficacy of paroxetine and amitriptyline in posttraumatic stress disorder: an open-label comparative study","volume":"21","author":"Celik","year":"2011","journal-title":"Bull Clin Psychopharmacol"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0150","first-page":"274","article-title":"Glutamate and post-traumatic stress disorder: toward a psychobiology of dissociation","volume":"4","author":"Chambers","year":"1999","journal-title":"Semin Clin Neuropsychiatry"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0155","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1037\/0735-7044.113.5.902","article-title":"Repeated restraint stress facilitates fear conditioning independently of causing hippocampal CA3 dendritic atrophy [In Process Citation]","volume":"113","author":"Conrad","year":"1999","journal-title":"Behav Neurosci"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0160","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1002\/neu.20025","article-title":"Chronic stress alters dendritic morphology in rat medial prefrontal cortex","volume":"60","author":"Cook","year":"2004","journal-title":"J Neurobiol"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0165","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1001\/archpsyc.1990.01810150059010","article-title":"Treatment of posttraumatic stress disorder with amitriptyline and placebo","volume":"47","author":"Davidson","year":"1990","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0170","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1176\/ajp.150.7.1024","article-title":"Predicting response to amitriptyline in posttraumatic stress disorder","volume":"150","author":"Davidson","year":"1993","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0175","doi-asserted-by":"crossref","first-page":"465","DOI":"10.2165\/00023210-200620060-00003","article-title":"Long-term pharmacotherapy for post-traumatic stress disorder","volume":"20","author":"Davis","year":"2006","journal-title":"CNS Drugs"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0180","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/0014-2999(94)90406-5","article-title":"Effect of chronic treatment with the antidepressant tianeptine on the hypothalamo-pituitary-adrenal axis","volume":"251","author":"Delbende","year":"1994","journal-title":"Eur J Pharmacol"},{"issue":"Suppl. 5","key":"10.1016\/j.pnpbp.2013.01.001_bb0185","doi-asserted-by":"crossref","first-page":"S491","DOI":"10.1016\/j.euroneuro.2004.09.003","article-title":"Preclinical research on stress, memory, and the brain in the development of pharmacotherapy for depression","volume":"14","author":"Diamond","year":"2004","journal-title":"Eur Neuropsychopharmacol"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0190","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/BF03033356","article-title":"Common efficacy of psychotropic drugs in restoring stress-induced impairment of prefrontal plasticity","volume":"10","author":"Dupin","year":"2006","journal-title":"Neurotox Res"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0195","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1080\/09658210444000025","article-title":"Intrusive re-experiencing in post-traumatic stress disorder: phenomenology, theory, and therapy","volume":"12","author":"Ehlers","year":"2004","journal-title":"Memory"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0200","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0165-0327(01)00351-2","article-title":"Are the neural substrates of memory the final common pathway in posttraumatic stress disorder (PTSD)?","volume":"70","author":"Elzinga","year":"2002","journal-title":"J Affect Disord"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0205","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.bbr.2004.11.004","article-title":"Piracetam counteracts the effects of amitriptyline on inhibitory avoidance in CD1 mice","volume":"159","author":"Everss","year":"2005","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0210","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.neulet.2010.12.006","article-title":"Cage mate separation in pair-housed male rats evokes an acute stress corticosterone response","volume":"489","author":"Ferland","year":"2011","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0215","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/0014-2999(95)00172-H","article-title":"Biochemical and behaviour changes induced by acute stress in a chronic variate stress model of depression: the effect of Amitriptyline","volume":"280","author":"Ferretti","year":"1995","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0220","first-page":"103","article-title":"Protective actions of carbocromene against amitriptyline-induced cardiotoxicity in anesthetized rats","volume":"279","author":"Fiedler","year":"1986","journal-title":"Arch Int Pharmacodyn Ther"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0225","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1176\/ajp.145.10.1289","article-title":"A randomized clinical trial of phenelzine and imipramine for posttraumatic stress disorder","volume":"145","author":"Frank","year":"1988","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0230","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.pbb.2008.01.022","article-title":"Changes in brain oxidative metabolism induced by inhibitory avoidance learning and acute administration of amitriptyline","volume":"89","author":"Gonzalez-Pardo","year":"2008","journal-title":"Pharmacol Biochem Behav"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0235","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1023\/B:JOTS.0000029266.88369.fd","article-title":"Characteristics and content of intrusive memories in PTSD and their changes with treatment","volume":"17","author":"Hackmann","year":"2004","journal-title":"J Trauma Stress"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0240","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1097\/00004583-199609000-00022","article-title":"Clonidine for posttraumatic stress disorder in preschool children","volume":"35","author":"Harmon","year":"1996","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0245","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0306-4530(99)00035-9","article-title":"The potential role of hypocortisolism in the pathophysiology of stress-related bodily disorders","volume":"25","author":"Heim","year":"2000","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0250","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1177\/026988110001400110","article-title":"Selective serotonin reuptake inhibitors in post-traumatic stress disorder","volume":"14","author":"Hidalgo","year":"2000","journal-title":"J Psychopharmacol"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0255","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1111\/j.1755-5949.2010.00227.x","article-title":"Effect of acute posttrauma propranolol on PTSD outcome and physiological responses during script-driven imagery","volume":"18","author":"Hoge","year":"2012","journal-title":"CNS Neurosci Ther"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0260","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1378\/chest.66.3.304","article-title":"Amitriptyline cardiotoxicity","volume":"66","author":"Hong","year":"1974","journal-title":"Chest"},{"issue":"Suppl. 5","key":"10.1016\/j.pnpbp.2013.01.001_bb0265","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1097\/00004850-199206005-00003","article-title":"Serotonin, panic disorder and agoraphobia: short-term and long-term efficacy of citalopram in panic disorders","volume":"6","author":"Humble","year":"1992","journal-title":"Int Clin Psychopharmacol"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0270","first-page":"1088","article-title":"Pharmacotherapy for post-traumatic stress disorder \u2014 a systematic review and meta-analysis","volume":"96","author":"Ipser","year":"2006","journal-title":"S Afr Med J"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0275","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1097\/00008877-199102000-00006","article-title":"Effects of tianeptine on spontaneous alternation, simple and concurrent spatial discrimination learning and on alcohol-induced alternation deficits in mice","volume":"2","author":"Jaffard","year":"1991","journal-title":"Behav Pharmacol"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0280","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1034\/j.1600-0447.2003.00065.x","article-title":"Olanzapine in the treatment-resistant, combat-related PTSD\u2014a series of case reports","volume":"107","author":"Jakovljevic","year":"2003","journal-title":"Acta Psychiatr Scand"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0285","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1046\/j.1460-9568.2003.02845.x","article-title":"Acute stress increases calcium current amplitude in rat hippocampus: temporal changes in physiology and gene expression","volume":"18","author":"Joels","year":"2003","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0290","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1007\/BF00547046","article-title":"A comparison of the cardiovascular effects and subjective tolerability of binedaline and amitriptylene in healthy volunteers","volume":"27","author":"Joubert","year":"1985","journal-title":"Eur J Clin Pharmacol"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0295","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1097\/00002826-199002000-00005","article-title":"Lack of cardiovascular side effects of the new tricyclic antidepressant tianeptine. A double-blind, placebo-controlled study in young healthy volunteers","volume":"13","author":"Juvent","year":"1990","journal-title":"Clin Neuropharmacol"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0300","doi-asserted-by":"crossref","first-page":"15","DOI":"10.2165\/00023210-200822010-00002","article-title":"Neurobiological and clinical effects of the antidepressant tianeptine","volume":"22","author":"Kasper","year":"2008","journal-title":"CNS Drugs"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0305","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/0149-7634(81)90008-7","article-title":"Amitriptyline and scopolamine in an animal-model of depression","volume":"5","author":"Katz","year":"1981","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0310","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1002\/anxi.3070010404","article-title":"Pharmacotherapy of post-traumatic stress disorder with a novel psychotropic","volume":"1","author":"Katz","year":"1994","journal-title":"Anxiety"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0315","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1046\/j.1365-2125.1996.39016.x","article-title":"The effects of reboxetine and amitriptyline, with and without alcohol on cognitive function and psychomotor performance","volume":"42","author":"Kerr","year":"1996","journal-title":"Br J Clin Pharmacol"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0320","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1046\/j.1460-9568.2002.02136.x","article-title":"The antidepressant tianeptine persistently modulates glutamate receptor currents of the hippocampal CA3 commissural associational synapse in chronically stressed rats","volume":"16","author":"Kole","year":"2002","journal-title":"Eur J Neurosci"},{"issue":"Suppl. 1","key":"10.1016\/j.pnpbp.2013.01.001_bb0325","first-page":"29S","article-title":"Anticholinergic and blood pressure effects of mianserin, amitriptyline and placebo","volume":"5","author":"Kopera","year":"1978","journal-title":"Br J Clin Pharmacol"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0330","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1097\/00005053-199106000-00011","article-title":"Pharmacotherapy for posttraumatic stress disorder using phenelzine or imipramine","volume":"179","author":"Kosten","year":"1991","journal-title":"J Nerv Ment Dis"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0335","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/0304-3940(93)90174-J","article-title":"A single social stress-experience alters glutamate receptor-binding in rat hippocampal CA3 area","volume":"154","author":"Krugers","year":"1993","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0340","first-page":"431","article-title":"Influence of antidepressant drugs on learning and memory paradigms in mice","volume":"34","author":"Kumar","year":"1996","journal-title":"Indian J Exp Biol"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0345","first-page":"1858","article-title":"Cardiovascular tolerance to tianeptine","volume":"20","author":"Lasnier","year":"1991","journal-title":"Presse Med"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0350","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.pnpbp.2005.10.013","article-title":"Acute effects of tianeptine on circulating neurotransmitters and cardiovascular parameters","volume":"30","author":"Lechin","year":"2006","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0355","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1111\/j.1365-2125.1978.tb01616.x","article-title":"Amitriptyline- and mianserin-induced changes in acquisition of paired-association learning-task","volume":"5","author":"Liljequist","year":"1978","journal-title":"Br J Clin Pharmacol"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0360","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1002\/mus.880151208","article-title":"Differential effects of amitriptyline on sudomotor, cardiovagal, and adrenergic function in human subjects","volume":"15","author":"Low","year":"1992","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0365","doi-asserted-by":"crossref","first-page":"1957","DOI":"10.1111\/j.1471-4159.1993.tb09839.x","article-title":"Adrenalectomy attenuates stress-induced elevations in extracellular glutamate concentrations in the hippocampus","volume":"61","author":"Lowy","year":"1993","journal-title":"J Neurochem"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0370","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1046\/j.1471-4159.1995.65010268.x","article-title":"Effect of acute stress on hippocampal glutamate levels and spectrin proteolysis in young and aged rats","volume":"65","author":"Lowy","year":"1995","journal-title":"J Neurochem"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0375","doi-asserted-by":"crossref","first-page":"3534","DOI":"10.1523\/JNEUROSCI.16-10-03534.1996","article-title":"Chronic psychosocial stress causes apical dendritic atrophy of hippocampal CA3 pyramidal neurons in subordinate tree shrews","volume":"16","author":"Magarinos","year":"1996","journal-title":"J Neurosci"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0380","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/S0014-2999(99)00163-6","article-title":"Effects of antidepressants and benzodiazepine treatments on the dendritic structure of CA3 pyramidal neurons after chronic stress","volume":"371","author":"Magarinos","year":"1999","journal-title":"Eur J Pharmacol"},{"issue":"Suppl. 1","key":"10.1016\/j.pnpbp.2013.01.001_bb0385","first-page":"53S","article-title":"Effects of amitriptyline and mianserin on psychomotor skills and memory in man","volume":"5","author":"Mattila","year":"1978","journal-title":"Br J Clin Pharmacol"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0390","doi-asserted-by":"crossref","first-page":"318S","DOI":"10.1016\/S0924-9338(02)00650-8","article-title":"Structural plasticity and tianeptine: cellular and molecular targets","volume":"17","author":"McEwen","year":"2002","journal-title":"Eur Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0395","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1038\/mp.2009.80","article-title":"The neurobiological properties of tianeptine (Stablon): from monoamine hypothesis to glutamatergic modulation","author":"McEwen","year":"2010","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0400","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.brainres.2007.05.042","article-title":"The effects of chronic stress on Hippocampal morphology and function: an evaluation of chronic restraint paradigms","volume":"1161","author":"McLaughlin","year":"2007","journal-title":"Brain Res"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0405","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S0149-7634(02)00005-2","article-title":"Tianeptine: 5-HT uptake sites and 5-HT1-7 receptors modulate memory formation in an autoshaping Pavlovian\/instrumental task","volume":"26","author":"Meneses","year":"2002","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0410","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1016\/S0022-3565(24)39023-8","article-title":"S18616, a highly potent spiroimidazoline agonist at alpha(2)-adrenoceptors: II. Influence on monoaminergic transmission, motor function, and anxiety in comparison with dexmedetomidine and clonidine","volume":"295","author":"Millan","year":"2000","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0415","doi-asserted-by":"crossref","first-page":"1650","DOI":"10.1111\/j.1471-4159.1993.tb13387.x","article-title":"Stress preferentially increases extraneuronal levels of excitatory amino acids in the prefrontal cortex: comparison to hippocampus and basal ganglia","volume":"60","author":"Moghaddam","year":"1993","journal-title":"J Neurochem"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0420","first-page":"887.10","article-title":"The enhancement of long-term (24hr) spatial memory by tianeptine, memantine and CPP supports the hypothesis that a reduction of NMDA receptor activity during learning will enhance memory","volume":"35","author":"Munoz","year":"2005","journal-title":"Soc Neurosci Abstr"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0425","doi-asserted-by":"crossref","first-page":"7768","DOI":"10.1523\/JNEUROSCI.16-23-07768.1996","article-title":"Dopamine and spatial working memory in rats and monkeys: pharmacological reversal of stress-induced impairment","volume":"16","author":"Murphy","year":"1996","journal-title":"J Neurosci"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0430","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1017\/S1092852900016862","article-title":"The role of the glutamatergic system in posttraumatic stress disorder","volume":"13","author":"Nair","year":"2008","journal-title":"CNS Spectr"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0435","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1097\/00004850-199707000-00008","article-title":"An open trial of moclobemide in the treatment of post-traumatic stress disorder","volume":"12","author":"Neal","year":"1997","journal-title":"Int Clin Psychopharmacol"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0440","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jpsychires.2005.07.005","article-title":"Posttraumatic stress disorder: a state-of-the-science review","volume":"40","author":"Nemeroff","year":"2006","journal-title":"J Psychiatr Res"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0445","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/S0959-4388(00)00080-5","article-title":"Neurobiology of posttraumatic stress disorder","volume":"10","author":"Newport","year":"2000","journal-title":"Curr Opin Neurobiol"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0450","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.eurpsy.2005.03.007","article-title":"A comparative study of fluoxetine, moclobemide, and tianeptine in the treatment of posttraumatic stress disorder following an earthquake","volume":"21","author":"Onder","year":"2006","journal-title":"Eur Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0455","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1037\/0022-006X.58.3.329","article-title":"Psychometric profile of posttraumatic stress disorder, anxious, and healthy Vietnam veterans: correlations with psychophysiologic responses","volume":"58","author":"Orr","year":"1990","journal-title":"J Consult Clin Psychol"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0460","doi-asserted-by":"crossref","first-page":"1783","DOI":"10.1038\/sj.npp.1301291","article-title":"Quetiapine prevents anhedonia induced by acute or chronic stress","volume":"32","author":"Orsetti","year":"2007","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0465","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/S0006-3223(00)01088-X","article-title":"Glucocorticoid receptors in major depression: relevance to pathophysiology and treatment","volume":"49","author":"Pariante","year":"2001","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0470","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1016\/S0006-3223(01)01255-0","article-title":"Chronic psychosocial stress impairs learning and memory and increases sensitivity to yohimbine in adult rats","volume":"50","author":"Park","year":"2001","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0475","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/S0166-4328(97)00066-1","article-title":"Prevention of amitriptyline-induced avoidance impairment by tacrine in mice","volume":"89","author":"Pavone","year":"1997","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0480","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1177\/0891988703256050","article-title":"Prazosin reduces trauma-related nightmares in older men with chronic posttraumatic stress disorder","volume":"16","author":"Peskind","year":"2003","journal-title":"J Geriatr Psychiatry Neurol"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0485","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1177\/026988110001400105","article-title":"The effects of some antidepressant drugs on prepulse inhibition of the acoustic startle (eyeblink) response and the N1\/P2 auditory evoked response in man","volume":"14","author":"Phillips","year":"2000","journal-title":"J Psychopharmacol"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0490","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/S0006-3223(01)01279-3","article-title":"Pilot study of secondary prevention of posttraumatic stress disorder with propranolol","volume":"51","author":"Pitman","year":"2002","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0495","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1016\/S0028-3908(03)00066-2","article-title":"Neuroprotective properties of tianeptine: interactions with cytokines","volume":"44","author":"Plaisant","year":"2003","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0500","first-page":"541A","article-title":"Neuroprotective properties of tianeptine against neonatal excitotoxic brain lesions: Effects of cytokines","volume":"53","author":"Plaisant","year":"2003","journal-title":"Pediatr Res"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0505","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1037\/0033-2909.133.5.725","article-title":"The psychophysiology of posttraumatic stress disorder: a meta-analysis","volume":"133","author":"Pole","year":"2007","journal-title":"Psychol Bull"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0510","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1007\/s00213-003-1577-9","article-title":"Gender difference in the prevention of hyperanxiety in adult prenatally stressed rats by chronic treatment with amitriptyline","volume":"171","author":"Poltyrev","year":"2004","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0515","first-page":"475","article-title":"The use of clonidine in post-traumatic stress disorder","volume":"91","author":"Porter","year":"1999","journal-title":"J Natl Med Assoc"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0520","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/0304-3940(93)90297-X","article-title":"The effect of long-term treatment with antidepressant drugs on the hippocampal mineralocorticoid and glucocorticoid receptors in rats","volume":"161","author":"Przegalinski","year":"1993","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0525","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.neuropharm.2008.06.068","article-title":"Antidepressants reverse the attenuation of the neurotrophic MEK\/MAPK cascade in frontal cortex by elevated platform stress; reversal of effects on LTP is associated with GluA1 phosphorylation","volume":"56","author":"Qi","year":"2009","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0530","doi-asserted-by":"crossref","first-page":"565","DOI":"10.4088\/JCP.v63n0705","article-title":"Prazosin reduces nightmares in combat veterans with posttraumatic stress disorder","volume":"63","author":"Raskind","year":"2002","journal-title":"J Clin Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0535","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1176\/appi.ajp.160.2.371","article-title":"Reduction of nightmares and other PTSD symptoms in combat veterans by prazosin: a placebo-controlled study","volume":"160","author":"Raskind","year":"2003","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0540","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1016\/S0006-3223(99)00185-7","article-title":"Low baseline and yohimbine-stimulated plasma neuropeptide Y (NPY) levels in combat-related PTSD","volume":"47","author":"Rasmusson","year":"2000","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0545","doi-asserted-by":"crossref","first-page":"88","DOI":"10.3389\/fnbeh.2011.00088","article-title":"Cellular correlates of enhanced anxiety caused by acute treatment with the selective serotonin reuptake inhibitor fluoxetine in rats","volume":"5","author":"Ravinder","year":"2011","journal-title":"Front Behav Neurosci"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0550","doi-asserted-by":"crossref","first-page":"2179","DOI":"10.1073\/pnas.0307294101","article-title":"Chronic restraint stress up-regulates GLT-1 mRNA and protein expression in the rat hippocampus: reversal by tianeptine","volume":"101","author":"Reagan","year":"2004","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0555","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1097\/00005053-200006000-00003","article-title":"Individual predictors of traumatic reactions in firefighters","volume":"188","author":"Regehr","year":"2000","journal-title":"J Nerv Ment Dis"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0560","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1176\/ajp.146.4.513","article-title":"A controlled trial of desipramine in 18 men with posttraumatic stress disorder","volume":"146","author":"Reist","year":"1989","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0565","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1177\/0269881108094617","article-title":"Glutamate and cortisol\u2014a critical confluence in PTSD?","volume":"22","author":"Reul","year":"2008","journal-title":"J Psychopharmacol"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0570","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1210\/endo.133.1.8391426","article-title":"Chronic treatment of rats with the antidepressant amitriptyline attenuates the activity of the hypothalamic\u2013pituitary\u2013adrenocortical system","volume":"133","author":"Reul","year":"1993","journal-title":"Endocrinology"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0575","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/S0005-7967(98)00013-8","article-title":"Intrusive cognitions, coping strategies and emotional responses in depression, post-traumatic stress disorder and a non-clinical population","volume":"36","author":"Reynolds","year":"1998","journal-title":"Behav Res Ther"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0580","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/S0005-7967(98)00132-6","article-title":"Intrusive memories in depression and posttraumatic stress disorder","volume":"37","author":"Reynolds","year":"1999","journal-title":"Behav Res Ther"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0585","doi-asserted-by":"crossref","first-page":"3109","DOI":"10.1111\/j.1460-9568.2007.05560.x","article-title":"Acute stress-mediated increases in extracellular glutamate levels in the rat amygdala: differential effects of antidepressant treatment","volume":"25","author":"Reznikov","year":"2007","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0590","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.bbr.2011.01.051","article-title":"Acute and chronic anxiogenic-like response to fluoxetine in rats in the elevated plus-maze: modulation by stressful handling","volume":"220","author":"Robert","year":"2011","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0595","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1016\/j.jpsychires.2011.01.013","article-title":"Epigenetic modification of hippocampal Bdnf DNA in adult rats in an animal model of post-traumatic stress disorder","volume":"45","author":"Roth","year":"2011","journal-title":"J Psychiatr Res"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0605","doi-asserted-by":"crossref","first-page":"520","DOI":"10.4088\/JCP.v69n0402","article-title":"Placebo-controlled trial of risperidone augmentation for selective serotonin reuptake inhibitor-resistant civilian posttraumatic stress disorder","volume":"69","author":"Rothbaum","year":"2008","journal-title":"J Clin Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0610","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/0014-2999(93)90586-7","article-title":"Tianeptine raises dopamine and blocks stress-induced noradrenaline release in the rat frontal cortex","volume":"236","author":"Sacchetti","year":"1993","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0615","doi-asserted-by":"crossref","first-page":"3638","DOI":"10.1523\/JNEUROSCI.22-09-03638.2002","article-title":"Overcoming the effects of stress on synaptic plasticity in the intact hippocampus: rapid actions of serotonergic and antidepressant agents","volume":"22","author":"Shakesby","year":"2002","journal-title":"J Neurosci"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0620","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/0165-1781(88)90057-1","article-title":"A controlled trial of phenelzine in posttraumatic stress disorder","volume":"24","author":"Shestatzky","year":"1988","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0625","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1016\/0091-3057(86)90196-6","article-title":"Biochemical and behavioral correlates of chronic stress: effects of tricyclic antidepressants","volume":"24","author":"Soblosky","year":"1986","journal-title":"Pharmacol Biochem Behav"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0630","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1037\/0022-3514.55.2.279","article-title":"Coping, locus of control, social support, and combat-related posttraumatic stress disorder: a prospective study","volume":"55","author":"Solomon","year":"1988","journal-title":"J Pers Soc Psychol"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0635","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1111\/j.2044-8260.1989.tb00823.x","article-title":"Locus of control and combat-related post-traumatic stress disorder: the intervening role of battle intensity, threat appraisal and coping","volume":"28","author":"Solomon","year":"1989","journal-title":"Br J Clin Psychol"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0640","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1001\/archpsyc.1993.01820160036003","article-title":"Abnormal noradrenergic function in posttraumatic stress disorder","volume":"50","author":"Southwick","year":"1993","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0645","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1016\/S0006-3223(99)00219-X","article-title":"Role of norepinephrine in the pathophysiology and treatment of posttraumatic stress disorder","volume":"46","author":"Southwick","year":"1999","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0650","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1016\/S0006-3223(99)00107-9","article-title":"Yohimbine use in a natural setting: effects on posttraumatic stress disorder","volume":"46","author":"Southwick","year":"1999","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0655","first-page":"242","article-title":"Neurotransmitter alterations in PTSD: catecholamines and serotonin","volume":"4","author":"Southwick","year":"1999","journal-title":"Semin Clin Neuropsychiatry"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0660","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.janxdis.2005.02.004","article-title":"Changes in intrusive memories associated with imaginal reliving in posttraumatic stress disorder","volume":"20","author":"Speckens","year":"2006","journal-title":"J Anxiety Disord"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0665","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1080\/09658210701256449","article-title":"Intrusive memories and rumination in patients with post-traumatic stress disorder: a phenomenological comparison","volume":"15","author":"Speckens","year":"2007","journal-title":"Memory"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0670","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1007\/BF02245119","article-title":"Amitriptyline, clovoxamine and cognitive function: a placebo-controlled comparison in depressed outpatients","volume":"108","author":"Spring","year":"1992","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0675","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1016\/j.neubiorev.2006.11.010","article-title":"PTSD and stress sensitisation: a tale of brain and body Part 1: human studies","volume":"31","author":"Stam","year":"2007","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0680","doi-asserted-by":"crossref","first-page":"1777","DOI":"10.1176\/appi.ajp.159.10.1777","article-title":"Adjunctive olanzapine for SSRI-resistant combat-related PTSD: a double-blind, placebo-controlled study","volume":"159","author":"Stein","year":"2002","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0685","first-page":"CD002795","article-title":"Pharmacotherapy for post traumatic stress disorder (PTSD)","author":"Stein","year":"2006","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0690","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1002\/da.20292","article-title":"Noradrenergic dysfunction and the psychopharmacology of posttraumatic stress disorder","volume":"25","author":"Strawn","year":"2008","journal-title":"Depress Anxiety"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0695","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1097\/00004714-200202000-00013","article-title":"The alpha1-adrenergic antagonist prazosin improves sleep and nightmares in civilian trauma posttraumatic stress disorder","volume":"22","author":"Taylor","year":"2002","journal-title":"J Clin Psychopharmacol"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0700","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/j.biopsych.2005.09.023","article-title":"Daytime prazosin reduces psychological distress to trauma specific cues in civilian trauma posttraumatic stress disorder","volume":"59","author":"Taylor","year":"2006","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0705","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1016\/S0006-3223(03)00412-8","article-title":"Immediate treatment with propranolol decreases posttraumatic stress disorder two months after trauma","volume":"54","author":"Vaiva","year":"2003","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0710","doi-asserted-by":"crossref","first-page":"S49","DOI":"10.1002\/hup.270","article-title":"The psychobiology and psychopharmacology of PTSD","volume":"16","author":"Van der Kolk","year":"2001","journal-title":"Hum Psychopharmacol Clin Exp"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0715","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1007\/s00213-002-1116-0","article-title":"Differential effects of amitriptyline, nefazodone and paroxetine on performance and brain indices of visual selective attention and working memory","volume":"162","author":"van Laar","year":"2002","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0720","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S0278-5846(02)00338-X","article-title":"Role of selective serotonin reuptake inhibitors in psychiatric disorders: a comprehensive review","volume":"27","author":"Vaswani","year":"2003","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0725","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1093\/milmed\/162.9.616","article-title":"Pharmacological management of post-traumatic stress disorder: clinical summary of a five-year retrospective study, 1990\u20131995","volume":"162","author":"Viola","year":"1997","journal-title":"Mil Med"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0730","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1080\/10253890600610973","article-title":"Differential effects of predator stress and the antidepressant tianeptine on physiological plasticity in the hippocampus and basolateral amygdala","volume":"9","author":"Vouimba","year":"2006","journal-title":"Stress"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0735","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1002\/hipo.450020410","article-title":"Phenytoin prevents stress- and corticosterone-induced atrophy of CA3 pyramidal neurons","volume":"2","author":"Watanabe","year":"1992","journal-title":"Hippocampus"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0740","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/0014-2999(92)90830-W","article-title":"Tianeptine attenuates stress-induced morphological changes in the hippocampus","volume":"222","author":"Watanabe","year":"1992","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0745","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/0006-8993(92)91597-8","article-title":"Stress induces atrophy of apical dendrites of hippocampal CA3 pyramidal neurons","volume":"588","author":"Watanabe","year":"1992","journal-title":"Brain Res"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0750","doi-asserted-by":"crossref","first-page":"11045","DOI":"10.1523\/JNEUROSCI.3652-05.2005","article-title":"Reversal of maternal programming of stress responses in adult offspring through methyl supplementation: altering epigenetic marking later in life","volume":"25","author":"Weaver","year":"2005","journal-title":"J Neurosci"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0755","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1002\/neu.1079","article-title":"Dendritic reorganization in pyramidal neurons in medial prefrontal cortex after chronic corticosterone administration","volume":"49","author":"Wellman","year":"2001","journal-title":"J Neurobiol"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0760","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s00213-005-0048-x","article-title":"A selective test for antidepressant treatments using rats bred for stress-induced reduction of motor activity in the swim test","volume":"182","author":"West","year":"2005","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0765","doi-asserted-by":"crossref","first-page":"4288","DOI":"10.1523\/JNEUROSCI.0406-05.2005","article-title":"Behavioral stress enhances hippocampal CA1 long-term depression through the blockade of the glutamate uptake","volume":"25","author":"Yang","year":"2005","journal-title":"J Neurosci"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0770","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1007\/3-540-28082-0_13","article-title":"Neuroendocrine aspects of PTSD","author":"Yehuda","year":"2005","journal-title":"Handb Exp Pharmacol"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0775","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1254\/jjp.45.335","article-title":"Cardiovascular effects of paroxetine, a newly developed antidepressant, in anesthetized dogs in comparison with those of imipramine, amitriptyline and clomipramine","volume":"45","author":"Yokota","year":"1987","journal-title":"Jpn J Pharmacol"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0780","first-page":"157","article-title":"The effects of single and repeated administration of MAO inhibitors on acoustic startle response in rats","volume":"45","author":"Zajaczkowski","year":"1993","journal-title":"Pol J Pharmacol"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0785","first-page":"115","article-title":"Fluoxetine-induced anxiety and nervousness","volume":"58","author":"Zienowicz","year":"2006","journal-title":"Pharmacol Rep"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0790","first-page":"6","article-title":"An animal model of PTSD which integrates inescapable predator exposure and social instability","volume":"15","author":"Zoladz","year":"2010","journal-title":"Culture Psychol Neurosci"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0795","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1080\/10253890701768613","article-title":"Acute episodes of predator exposure in conjunction with chronic social instability as an animal model of post-traumatic stress disorder","volume":"11","author":"Zoladz","year":"2008","journal-title":"Stress"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0800","doi-asserted-by":"crossref","first-page":"311","DOI":"10.2174\/157015908787386096","article-title":"Tianeptine: an antidepressant with memory-protective properties","volume":"6","author":"Zoladz","year":"2008","journal-title":"Curr Neuropharmacol"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0805","doi-asserted-by":"crossref","first-page":"3143","DOI":"10.3390\/ph3103143","article-title":"Beneficial effects of tianeptine on hippocampus-dependent long-term memory and stress-induced alterations of brain structure and function","volume":"3","author":"Zoladz","year":"2010","journal-title":"Pharmaceuticals"},{"key":"10.1016\/j.pnpbp.2013.01.001_bb0810","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1016\/j.psyneuen.2012.02.007","article-title":"Psychosocial animal model of PTSD produces a long-lasting traumatic memory, an increase in general anxiety and PTSD-like glucocorticoid abnormalities","volume":"37","author":"Zoladz","year":"2012","journal-title":"Psychoneuroendocrinology"}],"container-title":["Progress in Neuro-Psychopharmacology and Biological Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278584613000031?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278584613000031?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T16:58:02Z","timestamp":1745945882000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0278584613000031"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7]]},"references-count":161,"alternative-id":["S0278584613000031"],"URL":"https:\/\/doi.org\/10.1016\/j.pnpbp.2013.01.001","relation":{},"ISSN":["0278-5846"],"issn-type":[{"value":"0278-5846","type":"print"}],"subject":[],"published":{"date-parts":[[2013,7]]}}}