{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T11:51:50Z","timestamp":1788954710570,"version":"build-2803163510"},"reference-count":59,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2013,8,1]],"date-time":"2013-08-01T00:00:00Z","timestamp":1375315200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,8,1]],"date-time":"2013-08-01T00:00:00Z","timestamp":1375315200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Nature Science Foundation of China","award":["81102432"],"award-info":[{"award-number":["81102432"]}]},{"name":"Doctoral Fund of Ministry of Education of China","award":["20112134120005"],"award-info":[{"award-number":["20112134120005"]}]},{"name":"Project of Innovative Research Team in Liaoning Colleges and Universities","award":["LT2010098"],"award-info":[{"award-number":["LT2010098"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Progress in Neuro-Psychopharmacology and Biological Psychiatry"],"published-print":{"date-parts":[[2013,8]]},"DOI":"10.1016\/j.pnpbp.2013.04.006","type":"journal-article","created":{"date-parts":[[2013,4,18]],"date-time":"2013-04-18T06:28:19Z","timestamp":1366266499000},"page":"107-116","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":50,"special_numbering":"C","title":["Neuronal injury, but not microglia activation, is associated with ketamine-induced experimental schizophrenic model in mice"],"prefix":"10.1016","volume":"45","author":[{"given":"Yue","family":"Hou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongli","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guanbo","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyue","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"YaNan","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhihao","family":"Mao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingyu","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunfu","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.pnpbp.2013.04.006_bb0005","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1001\/archpsyc.55.3.225","article-title":"Absence of neurodegeneration and neural injury in the cerebral cortex in a sample of elderly patients with schizophrenia","volume":"55","author":"Arnold","year":"1998","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0010","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.pnpbp.2012.12.009","article-title":"Inhibition of central angiotensin II enhances memory function and reduces oxidative stress status in rat hippocampus","volume":"43","author":"Bild","year":"2013","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0015","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1016\/j.neubiorev.2010.10.008","article-title":"Oxidative stress in schizophrenia: an integrated approach","volume":"35","author":"Bitanihirwe","year":"2011","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0020","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1176\/appi.ajp.161.4.742","article-title":"Pathology of layer V pyramidal neurons in the prefrontal cortex of patients with schizophrenia","volume":"161","author":"Black","year":"2004","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0025","doi-asserted-by":"crossref","first-page":"301","DOI":"10.2174\/157015911795596595","article-title":"Oxidative stress in schizophrenia","volume":"9","author":"Bo\u0161kovi\u0107","year":"2011","journal-title":"Curr Neuropharmacol"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0030","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S0920-9964(02)00201-3","article-title":"Evidence for a decrease in basilar dendrites of pyramidal cells in schizophrenic medial prefrontal cortex","volume":"58","author":"Broadbelt","year":"2002","journal-title":"Schizophr Res"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0035","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S0024-3205(97)00228-2","article-title":"Neurotransmitter aberrations in schizophrenia: new perspectives and therapeutic implications","volume":"61","author":"Carlsson","year":"1997","journal-title":"Life Sci"},{"issue":"1","key":"10.1016\/j.pnpbp.2013.04.006_bb0040","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.bbr.2010.08.001","article-title":"Effect of \u2018chronic\u2019 versus \u2018acute\u2019 ketamine administration and its \u2018withdrawal\u2019 effect on behavioural alterations in mice: implications for experimental psychosis","volume":"216","author":"Chatterjee","year":"2011","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0045","first-page":"237","article-title":"Oxidative stress in schizophrenia-focusing on the main markers","volume":"23","author":"Ciobica","year":"2011","journal-title":"Psychiatr Danub"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0050","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1016\/j.expneurol.2007.11.013","article-title":"Adenosine A2A receptor blockade prevents memory dysfunction caused by beta-amyloid peptides but not by scopolamine or MK-801","volume":"210","author":"Cunha","year":"2008","journal-title":"Exp Neurol"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0055","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1007\/s00213-005-0117-1","article-title":"Supplementation of vitamin C with atypical antipsychotics reduces oxidative stress and improves the outcome of schizophrenia","volume":"182","author":"Dakhale","year":"2005","journal-title":"Psychopharmacology (Berl)"},{"issue":"2\u20133","key":"10.1016\/j.pnpbp.2013.04.006_bb0060","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/S0165-0173(99)00002-8","article-title":"An integrated view of pathophysiological models of schizophrenia","volume":"29","author":"Duncan","year":"1999","journal-title":"Brain Res Brain Res Rev"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0065","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/0166-4328(88)90157-X","article-title":"A new one-trial test for neurobiological studies of memory in rats","volume":"31","author":"Ennaceur","year":"1988","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0070","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1016\/j.jpsychires.2012.07.004","article-title":"Myelination and oxidative stress alterations in the cerebellum of the G72\/G30 transgenic schizophrenia mouse model","volume":"46","author":"Filiou","year":"2012","journal-title":"J Psychiatr Res"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0075","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1017\/S1461145710000805","article-title":"Decreased levels of glutathione, the major brain antioxidant, in post-mortem prefrontal cortex from patients with psychiatric disorders","volume":"14","author":"Gawryluk","year":"2011","journal-title":"Int J Neuropsychopharmacol"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0080","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1001\/archpsyc.57.1.65","article-title":"Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia","volume":"57","author":"Glantz","year":"2000","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0085","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1093\/oxfordjournals.schbul.a033430","article-title":"Neurocognitive deficits and functional outcome in schizophrenia: are we measuring the \u201cright stuff\u201d?","volume":"26","author":"Green","year":"2000","journal-title":"Schizophr Bull"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0090","doi-asserted-by":"crossref","first-page":"361","DOI":"10.4088\/JCP.v65n0312","article-title":"Cognitive functioning in schizophrenia: a consensus statement on its role in the definition and evaluation of effective treatments for the illness","volume":"65","author":"Harvey","year":"2004","journal-title":"J Clin Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0095","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.ejphar.2005.07.002","article-title":"Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of clozapine, but not haloperidol","volume":"519","author":"Hashimoto","year":"2005","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0100","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S0006-8993(96)01290-5","article-title":"MK-801-induced neuronal damage in rats","volume":"753","author":"Horv\u00e1th","year":"1997","journal-title":"Brain Res"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0105","doi-asserted-by":"crossref","first-page":"1486","DOI":"10.1016\/j.pnpbp.2006.06.001","article-title":"Differential effects of haloperidol, clozapine and olanzapine on learning and memory functions in mice","volume":"30","author":"Hou","year":"2006","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0110","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0165-3806(00)00059-6","article-title":"Maturation of locomotor and Fos responses to the NMDA antagonists, PCP and MK-801","volume":"122","author":"Jacobs","year":"2000","journal-title":"Brain Res Dev Brain Res"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0115","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1176\/ajp.148.10.1301","article-title":"Recent advances in the phencyclidine model of schizophrenia","volume":"148","author":"Javitt","year":"1991","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0120","first-page":"770","article-title":"Cerebral oligemic hypoxia and MK-801 treatment: effect on alternation behavior in mice","volume":"58","author":"J\u00f3zwiak","year":"2006","journal-title":"Pharmacol Rep"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0125","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.schres.2011.06.018","article-title":"Microglial activation in a neuroinflammational animal model of schizophrenia\u2014a pilot study","volume":"131","author":"Juckel","year":"2011","journal-title":"Schizophr Res"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0130","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1007\/s00213-010-2102-6","article-title":"The effects of NMDA receptor antagonists on attentional set-shifting task performance in mice","volume":"214","author":"Kos","year":"2011","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0140","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1001\/archpsyc.1994.03950030035004","article-title":"Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses","volume":"51","author":"Krystal","year":"1994","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0135","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/s00213-003-1582-z","article-title":"NMDA receptor antagonist effects, cortical glutamatergic function, and schizophrenia: toward a paradigm shift in medication development","volume":"169","author":"Krystal","year":"2003","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0145","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.brainres.2009.05.004","article-title":"Phencyclidine-induced cognitive deficits in mice are ameliorated by subsequent subchronic administration of donepezil: role of sigma-1 receptors","volume":"1279","author":"Kunitachi","year":"2009","journal-title":"Brain Res"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0150","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1631\/jzus.2006.B0981","article-title":"Imbalanced free radicals and antioxidant defense systems in schizophrenia: a comparative study","volume":"7","author":"Li","year":"2006","journal-title":"J Zhejiang Univ Sci B"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0155","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.nbd.2010.07.011","article-title":"Similarities in the behavior and molecular deficits in the frontal cortex between the neurotensin receptor subtype 1 knockout mice and chronic phencyclidine-treated mice: relevance to schizophrenia","volume":"40","author":"Li","year":"2010","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0160","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1111\/j.1440-1819.2009.01945.x","article-title":"Cytokines and schizophrenia: microglia hypothesis of schizophrenia","volume":"63","author":"Monji","year":"2009","journal-title":"Psychiatry Clin Neurosci"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0165","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.euroneuro.2009.08.001","article-title":"Mazindol attenuates ketamine-induced cognitive deficit in the attentional set shifting task in rats","volume":"20","author":"Nikiforuk","year":"2010","journal-title":"Eur Neuropsychopharmacol"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0170","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.neuroscience.2007.07.019","article-title":"Differential effects of the N-methyl-d-Aspartate receptor antagonist MK-801 on different stages of object recognition memory in mice","volume":"149","author":"Nilsson","year":"2007","journal-title":"Neuroscience"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0190","doi-asserted-by":"crossref","first-page":"2531","DOI":"10.1111\/j.1476-5381.1995.tb15106.x","article-title":"Enhancement of immobility in a forced swimming test by subacute or repeated treatment with phencyclidine: a new model of schizophrenia","volume":"116","author":"Noda","year":"1995","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0185","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/S0014-2999(97)00067-8","article-title":"Effects of antidepressants on phencyclidine-induced enhancement of immobility in a forced swimming test in mice","volume":"324","author":"Noda","year":"1997","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0180","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/S0893-133X(00)00138-X","article-title":"Repeated phencyclidine treatment induces negative symptom-like behavior in forced swimming test in mice: imbalance of prefrontal serotonergic and dopaminergic functions","volume":"23","author":"Noda","year":"2000","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0195","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.schres.2004.09.007","article-title":"Identification of separable cognitive factors in schizophrenia","volume":"72","author":"Nuechterlein","year":"2004","journal-title":"Schizophr Res"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0200","doi-asserted-by":"crossref","first-page":"1866","DOI":"10.1111\/j.1460-9568.2012.08130.x","article-title":"Cortical interneurons, immune factors and oxidative stress as early targets for schizophrenia","volume":"35","author":"O'Donnell","year":"2012","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0205","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1001\/archpsyc.1995.03950240016004","article-title":"Glutamate receptor dysfunction and schizophrenia","volume":"52","author":"Olney","year":"1995","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0210","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1002\/1531-8249(200010)48:4<556::AID-ANA2>3.0.CO;2-2","article-title":"Neurobiology of schizophrenia","volume":"48","author":"Pearlson","year":"2000","journal-title":"Ann Neurol"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0215","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1016\/j.neuroscience.2008.04.001","article-title":"Effects of sub-anesthetic doses of ketamine on rats' spatial and non-spatial recognition memory","volume":"154","author":"Pitsikas","year":"2008","journal-title":"Neuroscience"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0220","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/j.neuropharm.2009.12.009","article-title":"Decreased glutathione levels and altered antioxidant defense in an animal model of schizophrenia: long-term effects of perinatal phencyclidine administration","volume":"58","author":"Radonji\u0107","year":"2010","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0225","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1146\/annurev.immunol.021908.132528","article-title":"Microglial physiology: unique stimuli, specialized responses","volume":"27","author":"Ransohoff","year":"2009","journal-title":"Annu Rev Immunol"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0230","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1016\/S1734-1140(12)70879-4","article-title":"Mangiferin ameliorates 6-hydroxydopamine-induced cytotoxicity and oxidative stress in ketamine model of schizophrenia","volume":"64","author":"Rao","year":"2012","journal-title":"Pharmacol Rep"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0235","series-title":"Harrison's principles of internal medicine","first-page":"2710","article-title":"Mental disorders","author":"Reus","year":"2008"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0240","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/S0893-133X(97)00200-5","article-title":"Effects of continuous d-amphetamine and phencyclidine administration on social behaviour, stereotyped behaviour, and locomotor activity in rats","volume":"19","author":"Sams-Dodd","year":"1998","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0245","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1007\/BF00212843","article-title":"Attenuation of scopolamine-induced impairment of spontaneous alternation behavior by antagonist but not inverse agonist and agonist beta-carbolines","volume":"94","author":"Sarter","year":"1988","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0250","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1001\/archpsyc.1991.01810310036007","article-title":"Neuropsychological function in schizophrenia. Selective impairment in memory and learning","volume":"48","author":"Saykin","year":"1991","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0255","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1007\/s00401-006-0090-8","article-title":"Distribution of HLA-DR-positive microglia in schizophrenia reflects impaired cerebral lateralization","volume":"112","author":"Steiner","year":"2006","journal-title":"Acta Neuropathol"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0260","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.pnpbp.2012.06.013","article-title":"Risperidone reverses phencyclidine induced decrease in glutathione levels and alterations of antioxidant defense in rat brain","volume":"39","author":"Stojkovi\u0107","year":"2012","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0265","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1093\/schbul\/sbs052","article-title":"Inhibitory interneurons, oxidative stress, and schizophrenia","volume":"38","author":"Sullivan","year":"2012","journal-title":"Schizophr Bull"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0270","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1146\/annurev.pharmtox.42.082701.160735","article-title":"Glutamatergic mechanisms in schizophrenia","volume":"42","author":"Tsai","year":"2002","journal-title":"Annu Rev Pharmacol Toxicol"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0275","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1016\/j.biopsych.2008.04.025","article-title":"Microglia activation in recent-onset schizophrenia: a quantitative (R)-[11C]PK11195 positron emission tomography study","volume":"64","author":"van Berckel","year":"2008","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0280","first-page":"81","article-title":"Quantitative analysis of activated microglia, ramified and damage of processes in the frontal and temporal lobes of chronic schizophrenics","volume":"43","author":"Wierzba-Bobrowicz","year":"2005","journal-title":"Folia Neuropathol"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0285","doi-asserted-by":"crossref","DOI":"10.1016\/j.pnpbp.2013.02.015","article-title":"Free radicals, antioxidant defense systems, and schizophrenia","author":"Wu","year":"2013","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0290","doi-asserted-by":"crossref","first-page":"2011","DOI":"10.1089\/ars.2010.3603","article-title":"Antioxidants, redox signaling, and pathophysiology in schizophrenia: an integrative view","volume":"15","author":"Yao","year":"2011","journal-title":"Antioxid Redox Signal"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0295","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.bbr.2012.08.052","article-title":"Activated microglia are implicated in cognitive deficits, neuronal death, and successful recovery following intermittent ethanol exposure","volume":"236","author":"Zhao","year":"2013","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.pnpbp.2013.04.006_bb0300","doi-asserted-by":"crossref","first-page":"2172","DOI":"10.1016\/j.lfs.2005.09.022","article-title":"Effect of acute and chronic MK-801 administration on extracellular glutamate and ascorbic acid release in the prefrontal cortex of freely moving mice on line with open-field behavior","volume":"78","author":"Zuo","year":"2006","journal-title":"Life Sci"}],"container-title":["Progress in Neuro-Psychopharmacology and Biological Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278584613000729?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278584613000729?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T19:42:30Z","timestamp":1759520550000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0278584613000729"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,8]]},"references-count":59,"alternative-id":["S0278584613000729"],"URL":"https:\/\/doi.org\/10.1016\/j.pnpbp.2013.04.006","relation":{},"ISSN":["0278-5846"],"issn-type":[{"value":"0278-5846","type":"print"}],"subject":[],"published":{"date-parts":[[2013,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Neuronal injury, but not microglia activation, is associated with ketamine-induced experimental schizophrenic model in mice","name":"articletitle","label":"Article Title"},{"value":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pnpbp.2013.04.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}