{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:22:18Z","timestamp":1788870138113,"version":"build-2803163510"},"reference-count":60,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2014,4,1]],"date-time":"2014-04-01T00:00:00Z","timestamp":1396310400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science, and Technology of Japan","doi-asserted-by":"crossref","award":["13201342"],"award-info":[{"award-number":["13201342"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Ministry of Health, Labor, and Welfare of Japan","award":["04T-580"],"award-info":[{"award-number":["04T-580"]}]},{"name":"Hashiya Scholarship Foundation"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Progress in Neuro-Psychopharmacology and Biological Psychiatry"],"published-print":{"date-parts":[[2014,4]]},"DOI":"10.1016\/j.pnpbp.2013.12.017","type":"journal-article","created":{"date-parts":[[2014,1,2]],"date-time":"2014-01-02T17:46:38Z","timestamp":1388684798000},"page":"184-190","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":34,"special_numbering":"C","title":["Minocycline improves recognition memory and attenuates microglial activation in Gunn rat: A possible hyperbilirubinemia-induced animal model of schizophrenia"],"prefix":"10.1016","volume":"50","author":[{"given":"Kristian","family":"Liaury","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsuyoshi","family":"Miyaoka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiko","family":"Tsumori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Motohide","family":"Furuya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sadayuki","family":"Hashioka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rei","family":"Wake","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keiko","family":"Tsuchie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michiyo","family":"Fukushima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erlyn","family":"Limoa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andi Jayalangkara","family":"Tanra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Horiguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.pnpbp.2013.12.017_bb0005","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.pnpbp.2007.06.031","article-title":"The effect of atypical antipsychotics, perospirone, ziprasidone and quetiapine on microglial activation induced by interferon-gamma","volume":"32","author":"Bian","year":"2008","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"issue":"1","key":"10.1016\/j.pnpbp.2013.12.017_bb0010","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1002\/glia.22372","article-title":"Microglia as modulators of cognition and neuropsychiatric disorders","volume":"61","author":"Blank","year":"2013","journal-title":"Glia"},{"issue":"5","key":"10.1016\/j.pnpbp.2013.12.017_bb0015","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1212\/01.WNL.0000049936.85487.7A","article-title":"Minocycline for Huntington's disease: an open label study","volume":"60","author":"Bonelli","year":"2003","journal-title":"Neurology"},{"issue":"1\u20133","key":"10.1016\/j.pnpbp.2013.12.017_bb0020","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.ejphar.2012.09.005","article-title":"Minocycline restores spatial but not fear memory in olfactory bulbectomized rats","volume":"697","author":"Borre","year":"2012","journal-title":"Eur J Pharmacol"},{"issue":"9","key":"10.1016\/j.pnpbp.2013.12.017_bb0025","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1177\/0269881112444941","article-title":"Minocycline benefits negative symptoms in early schizophrenia: a randomised double-blind placebo-controlled clinical trial in patients on standard treatment","volume":"26","author":"Chaudhry","year":"2012","journal-title":"J Psychopharmacol"},{"issue":"5","key":"10.1016\/j.pnpbp.2013.12.017_bb0030","doi-asserted-by":"crossref","first-page":"391","DOI":"10.2165\/11632000-000000000-00000","article-title":"Minocycline: therapeutic potential in psychiatry","volume":"26","author":"Dean","year":"2012","journal-title":"CNS Drugs"},{"issue":"1\u20133","key":"10.1016\/j.pnpbp.2013.12.017_bb0035","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.schres.2007.08.007","article-title":"Disturbed social behavior and motivation in rats selectively bred for deficient sensorimotor gating","volume":"97","author":"Dieckmann","year":"2007","journal-title":"Schizophr Res"},{"issue":"11","key":"10.1016\/j.pnpbp.2013.12.017_bb0040","doi-asserted-by":"crossref","first-page":"1801","DOI":"10.2967\/jnumed.109.066647","article-title":"Neuroinflammation in schizophrenia-related psychosis: a PET study","volume":"50","author":"Doorduin","year":"2009","journal-title":"J Nucl Med"},{"issue":"3","key":"10.1016\/j.pnpbp.2013.12.017_bb0045","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1080\/09629350123895","article-title":"Serum IL-1beta, sIL-2R, IL-6, IL-8 and TNF-alpha in schizophrenic patients, relation with symptomatology and responsiveness to risperidone treatment","volume":"10","author":"Erbagci","year":"2001","journal-title":"Mediators Inflamm"},{"issue":"1\u20132","key":"10.1016\/j.pnpbp.2013.12.017_bb0050","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.jneuroim.2004.04.007","article-title":"Cytokine production, glutamate release and cell death in rat cultured astrocytes treated with unconjugated bilirubin and LPS","volume":"153","author":"Fernandes","year":"2004","journal-title":"J Neuroimmunol"},{"issue":"62","key":"10.1016\/j.pnpbp.2013.12.017_bb0055","first-page":"1742","article-title":"Minocycline corrects early, pre-plaque neuroinflammation and inhibits BACE-1 in a transgenic model of Alzheimer's disease-like amyloid pathology","volume":"9","author":"Ferretti","year":"2012","journal-title":"J Neuroinflammation"},{"key":"10.1016\/j.pnpbp.2013.12.017_bb0060","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1192\/bjp.126.5.414","article-title":"The brain stem in psychosis","volume":"126","author":"Fisman","year":"1975","journal-title":"Br J Psychiatry"},{"issue":"2","key":"10.1016\/j.pnpbp.2013.12.017_bb0065","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/j.pnpbp.2007.08.031","article-title":"Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of the antibiotic drug minocycline","volume":"32","author":"Fujita","year":"2008","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"issue":"3","key":"10.1016\/j.pnpbp.2013.12.017_bb0070","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1523\/JNEUROSCI.22-03-00612.2002","article-title":"Neurogenesis in the adult brain","volume":"22","author":"Gage","year":"2002","journal-title":"J Neurosci"},{"issue":"3","key":"10.1016\/j.pnpbp.2013.12.017_bb0075","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/0361-9230(90)90241-Q","article-title":"Startle response models of sensorimotor gating and habituation deficits in schizophrenia","volume":"25","author":"Geyer","year":"1990","journal-title":"Brain Res Bull"},{"issue":"1","key":"10.1016\/j.pnpbp.2013.12.017_bb0080","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1002\/jnr.490210104","article-title":"Axotomy of the rat facial nerve leads to increased CR3 complement receptor expression by activated microglial cells","volume":"21","author":"Graeber","year":"1988","journal-title":"J Neurosci Res"},{"issue":"3","key":"10.1016\/j.pnpbp.2013.12.017_bb0085","first-page":"230","article-title":"Hereditary acholuric jaundice in the rat","volume":"50","author":"Gunn","year":"1944","journal-title":"Can Med Assoc J"},{"issue":"4","key":"10.1016\/j.pnpbp.2013.12.017_bb0090","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/j.pnpbp.2009.02.013","article-title":"Hyperbilirubinemia-related behavioral and neuropathological changes in rats: a possible schizophrenia animal model","volume":"33","author":"Hayashida","year":"2009","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"issue":"2","key":"10.1016\/j.pnpbp.2013.12.017_bb0095","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1006\/exnr.1997.6561","article-title":"Microglia responses in the CNS following sciatic nerve transection in C57BL\/Wld(s) and BALB\/c mice","volume":"146","author":"He","year":"1997","journal-title":"Exp Neurol"},{"issue":"2\u20133","key":"10.1016\/j.pnpbp.2013.12.017_bb0100","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.neulet.2008.10.006","article-title":"Minocycline increases phosphorylation and membrane insertion of neuronal GluR1 receptors","volume":"447","author":"Imbesi","year":"2008","journal-title":"Neurosci Lett"},{"issue":"1\u20133","key":"10.1016\/j.pnpbp.2013.12.017_bb0105","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.schres.2011.06.018","article-title":"Microglial activation in a neuroinflammational animal model of schizophrenia \u2014 a pilot study","volume":"131","author":"Juckel","year":"2011","journal-title":"Schizophr Res"},{"issue":"1","key":"10.1016\/j.pnpbp.2013.12.017_bb0110","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.biopsych.2005.06.006","article-title":"Repeated methamphetamine treatment impairs recognition memory through a failure of novelty-induced ERK1\/2 activation in the prefrontal cortex of mice","volume":"59","author":"Kamei","year":"2006","journal-title":"Biol Psychiatry"},{"issue":"1\u20133","key":"10.1016\/j.pnpbp.2013.12.017_bb0115","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.schres.2007.01.019","article-title":"Risperidone significantly inhibits interferon-gamma-induced microglial activation in vitro","volume":"92","author":"Kato","year":"2007","journal-title":"Schizophr Res"},{"issue":"1\u20133","key":"10.1016\/j.pnpbp.2013.12.017_bb0120","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.schres.2011.08.005","article-title":"Adjunct minocycline to clozapine treated patients with persistent schizophrenia symptoms","volume":"133","author":"Kelly","year":"2011","journal-title":"Schizophr Res"},{"issue":"2","key":"10.1016\/j.pnpbp.2013.12.017_bb0125","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1152\/physrev.00011.2010","article-title":"Physiology of microglia","volume":"91","author":"Kettenmann","year":"2011","journal-title":"Physiol Rev"},{"key":"10.1016\/j.pnpbp.2013.12.017_bb0130","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.pnpbp.2012.02.001","article-title":"Viral infection, inflammation and schizophrenia","volume":"42","author":"Kneeland","year":"2013","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"issue":"5","key":"10.1016\/j.pnpbp.2013.12.017_bb0135","doi-asserted-by":"crossref","first-page":"520","DOI":"10.4088\/JCP.09m05117yel","article-title":"Adjuvant aspirin therapy reduces symptoms of schizophrenia spectrum disorders: results from a randomized, double-blind, placebo-controlled trial","volume":"71","author":"Laan","year":"2010","journal-title":"J Clin Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.12.017_bb0140","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.brainres.2007.03.080","article-title":"Minocycline, a second-generation tetracycline, as a neuroprotective agent in an animal model of schizophrenia","volume":"18","author":"Levkovitz","year":"2007","journal-title":"Brain Res"},{"issue":"2","key":"10.1016\/j.pnpbp.2013.12.017_bb0145","doi-asserted-by":"crossref","first-page":"138","DOI":"10.4088\/JCP.08m04666yel","article-title":"A double-blind, randomized study of minocycline for the treatment of negative and cognitive symptoms in early-phase schizophrenia","volume":"71","author":"Levkovitz","year":"2010","journal-title":"J Clin Psychiatry"},{"issue":"56","key":"10.1016\/j.pnpbp.2013.12.017_bb0150","first-page":"1742","article-title":"Morphological features of microglial cells in the hippocampal dentate gyrus of Gunn rat: a possible schizophrenia animal model","volume":"9","author":"Liaury","year":"2012","journal-title":"J Neuroinflammation"},{"issue":"1","key":"10.1016\/j.pnpbp.2013.12.017_bb0155","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1006\/exnr.1997.6762","article-title":"Role of glutamate receptor-mediated excitotoxicity in bilirubin-induced brain injury in the Gunn rat model","volume":"150","author":"McDonald","year":"1998","journal-title":"Exp Neurol"},{"issue":"2","key":"10.1016\/j.pnpbp.2013.12.017_bb0160","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1001\/archpsyc.1988.01800260109013","article-title":"Adult schizophrenia following prenatal exposure to an influenza epidemic","volume":"45","author":"Mednick","year":"1988","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.12.017_bb0165","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.pnpbp.2011.11.003","article-title":"Developmental neuroinflammation and schizophrenia","volume":"42","author":"Meyer","year":"2013","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"issue":"7","key":"10.1016\/j.pnpbp.2013.12.017_bb0170","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/j.biopsych.2011.04.013","article-title":"Meta-analysis of cytokine alterations in schizophrenia: clinical status and antipsychotic effects","volume":"70","author":"Miller","year":"2011","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.12.017_bb0175","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.pnpbp.2012.03.010","article-title":"Prenatal inflammation and neurodevelopment in schizophrenia: a review of human studies","volume":"42","author":"Miller","year":"2013","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2013.12.017_bb0180","doi-asserted-by":"crossref","first-page":"399","DOI":"10.4236\/ojpsych.2012.224056","article-title":"Minocycline for schizophrenia: a critical review","volume":"2","author":"Miyaoka","year":"2012","journal-title":"Open J Psychiatry"},{"issue":"1","key":"10.1016\/j.pnpbp.2013.12.017_bb0185","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/j.pnpbp.2006.08.013","article-title":"Possible antipsychotic effects of minocycline in patients with schizophrenia","volume":"31","author":"Miyaoka","year":"2007","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"issue":"5","key":"10.1016\/j.pnpbp.2013.12.017_bb0190","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1097\/WNF.0b013e3181593d45","article-title":"Minocycline as adjunctive therapy for schizophrenia: an open-label study","volume":"31","author":"Miyaoka","year":"2008","journal-title":"Clin Neuropharmacol"},{"issue":"2","key":"10.1016\/j.pnpbp.2013.12.017_bb0195","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1007\/s00213-007-0955-0","article-title":"Improvement by minocycline of methamphetamine-induced impairment of recognition memory in mice","volume":"196","author":"Mizoguchi","year":"2008","journal-title":"Psychopharmacology (Berl)"},{"issue":"2","key":"10.1016\/j.pnpbp.2013.12.017_bb0200","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1007\/BF03033242","article-title":"Schizophrenia as an inflammation-mediated dysbalance of glutamatergic neurotransmission","volume":"10","author":"Muller","year":"2006","journal-title":"Neurotox Res"},{"issue":"14","key":"10.1016\/j.pnpbp.2013.12.017_bb0205","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.2174\/138161208784480243","article-title":"COX-2 inhibition in schizophrenia and major depression","volume":"14","author":"Muller","year":"2008","journal-title":"Curr Pharm Des"},{"issue":"2","key":"10.1016\/j.pnpbp.2013.12.017_bb0210","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.molmed.2003.12.003","article-title":"Molecular basis of bilirubin-induced neurotoxicity","volume":"10","author":"Ostrow","year":"2004","journal-title":"Trends Mol Med"},{"key":"10.1016\/j.pnpbp.2013.12.017_bb0215","series-title":"The rat brain in stereotaxic coordinates","author":"Paxinos","year":"2007"},{"issue":"2","key":"10.1016\/j.pnpbp.2013.12.017_bb0220","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1093\/jnen\/59.2.137","article-title":"Increase in HLA-DR immunoreactive microglia in frontal and temporal cortex of chronic schizophrenics","volume":"59","author":"Radewicz","year":"2000","journal-title":"J Neuropathol Exp Neurol"},{"issue":"10","key":"10.1016\/j.pnpbp.2013.12.017_bb0225","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1038\/ng.940","article-title":"Genome-wide association study identifies five new schizophrenia loci","volume":"43","author":"Ripke","year":"2011","journal-title":"Nat Genet"},{"issue":"3","key":"10.1016\/j.pnpbp.2013.12.017_bb0230","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1002\/ajmg.10307","article-title":"Investigation of linkage and association\/linkage disequilibrium of HLA A-, DQA1-, DQB1-, and DRB1- alleles in 69 sib-pair- and 89 trio-families with schizophrenia","volume":"114","author":"Schwab","year":"2002","journal-title":"Am J Med Genet"},{"issue":"1","key":"10.1016\/j.pnpbp.2013.12.017_bb0235","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1006\/bbrc.1999.1646","article-title":"Inhibition of glutamate uptake by unconjugated bilirubin in cultured cortical rat astrocytes: role of concentration and pH","volume":"265","author":"Silva","year":"1999","journal-title":"Biochem Biophys Res Commun"},{"issue":"2","key":"10.1016\/j.pnpbp.2013.12.017_bb0240","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.jpsychires.2006.10.013","article-title":"Immunological aspects in the neurobiology of suicide: elevated microglial density in schizophrenia and depression is associated with suicide","volume":"42","author":"Steiner","year":"2008","journal-title":"J Psychiatr Res"},{"issue":"10","key":"10.1016\/j.pnpbp.2013.12.017_bb0245","first-page":"2112","article-title":"Should tetracycline treatment be used more extensively for rheumatoid arthritis? Metaanalysis demonstrates clinical benefit with reduction in disease activity","volume":"30","author":"Stone","year":"2003","journal-title":"J Rheumatol"},{"key":"10.1016\/j.pnpbp.2013.12.017_bb0250","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.nbd.2012.11.001","article-title":"Roles of glial cells in schizophrenia: possible targets for therapeutic approaches","volume":"53","author":"Takahashi","year":"2013","journal-title":"Neurobiol Dis"},{"issue":"10","key":"10.1016\/j.pnpbp.2013.12.017_bb0255","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1176\/appi.ajp.2010.09081187","article-title":"The hippocampal formation in schizophrenia","volume":"167","author":"Tamminga","year":"2010","journal-title":"Am J Psychiatry"},{"issue":"2","key":"10.1016\/j.pnpbp.2013.12.017_bb0260","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.ajp.2012.09.007","article-title":"The effects of antipsychotics on behavioral abnormalities of the Gunn rat (unconjugated hyperbilirubinemia rat), a rat model of schizophrenia","volume":"6","author":"Tsuchie","year":"2013","journal-title":"Asian Journal of Psychiatry"},{"issue":"9","key":"10.1016\/j.pnpbp.2013.12.017_bb0265","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1016\/j.biopsych.2008.04.025","article-title":"Microglia activation in recent-onset schizophrenia: a quantitative (R)-[11C]PK11195 positron emission tomography study","volume":"64","author":"van Berckel","year":"2008","journal-title":"Biol Psychiatry"},{"issue":"9690","key":"10.1016\/j.pnpbp.2013.12.017_bb0270","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/S0140-6736(09)60995-8","article-title":"Schizophrenia","volume":"374","author":"van Os","year":"2009","journal-title":"Lancet"},{"issue":"3\u20134","key":"10.1016\/j.pnpbp.2013.12.017_bb0275","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1023\/B:MEBR.0000043984.73063.d8","article-title":"Microglia","volume":"19","author":"van Rossum","year":"2004","journal-title":"Metab Brain Dis"},{"issue":"6","key":"10.1016\/j.pnpbp.2013.12.017_bb0280","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1038\/sj.mp.4002056","article-title":"Mice lacking the AMPA GluR1 receptor exhibit striatal hyperdopaminergia and \u2018schizophrenia-related\u2019 behaviors","volume":"13","author":"Wiedholz","year":"2008","journal-title":"Mol Psychiatry"},{"issue":"26","key":"10.1016\/j.pnpbp.2013.12.017_bb0285","doi-asserted-by":"crossref","first-page":"15769","DOI":"10.1073\/pnas.95.26.15769","article-title":"Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia","volume":"95","author":"Yrjanheikki","year":"1998","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"8","key":"10.1016\/j.pnpbp.2013.12.017_bb0290","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1016\/j.pnpbp.2006.05.015","article-title":"Protective effects of minocycline on behavioral changes and neurotoxicity in mice after administration of methamphetamine","volume":"30","author":"Zhang","year":"2006","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"issue":"1\u20133","key":"10.1016\/j.pnpbp.2013.12.017_bb0300","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ejphar.2006.05.047","article-title":"Protective effects of minocycline on 3,4-methylenedioxymethamphetamine-induced neurotoxicity in serotonergic and dopaminergic neurons of mouse brain","volume":"544","author":"Zhang","year":"2006","journal-title":"Eur J Pharmacol"},{"issue":"9","key":"10.1016\/j.pnpbp.2013.12.017_bb0295","doi-asserted-by":"crossref","first-page":"2004","DOI":"10.1038\/sj.npp.1301313","article-title":"Minocycline attenuates hyperlocomotion and prepulse inhibition deficits in mice after administration of the NMDA receptor antagonist dizocilpine","volume":"32","author":"Zhang","year":"2007","journal-title":"Neuropsychopharmacology"}],"container-title":["Progress in Neuro-Psychopharmacology and Biological Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278584613002972?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278584613002972?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,5]],"date-time":"2019-08-05T14:56:50Z","timestamp":1565017010000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0278584613002972"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4]]},"references-count":60,"alternative-id":["S0278584613002972"],"URL":"https:\/\/doi.org\/10.1016\/j.pnpbp.2013.12.017","relation":{},"ISSN":["0278-5846"],"issn-type":[{"value":"0278-5846","type":"print"}],"subject":[],"published":{"date-parts":[[2014,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Minocycline improves recognition memory and attenuates microglial activation in Gunn rat: A possible hyperbilirubinemia-induced animal model of schizophrenia","name":"articletitle","label":"Article Title"},{"value":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pnpbp.2013.12.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}