{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T12:01:13Z","timestamp":1793016073239,"version":"4.5.0"},"reference-count":75,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["ZYGX2013Z004"],"award-info":[{"award-number":["ZYGX2013Z004"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002338","name":"Ministry of Education of the People&apos;s Republic of China","doi-asserted-by":"publisher","award":["A03003023901010"],"award-info":[{"award-number":["A03003023901010"]}],"id":[{"id":"10.13039\/501100002338","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["30900483"],"award-info":[{"award-number":["30900483"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81171406"],"award-info":[{"award-number":["81171406"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81301279"],"award-info":[{"award-number":["81301279"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["91132721"],"award-info":[{"award-number":["91132721"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["61125304"],"award-info":[{"award-number":["61125304"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["61035006"],"award-info":[{"award-number":["61035006"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005890","name":"Ministry of Health of the People&apos;s Republic of China","doi-asserted-by":"publisher","award":["201002003"],"award-info":[{"award-number":["201002003"]}],"id":[{"id":"10.13039\/501100005890","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Progress in Neuro-Psychopharmacology and Biological Psychiatry"],"published-print":{"date-parts":[[2015,1]]},"DOI":"10.1016\/j.pnpbp.2014.07.007","type":"journal-article","created":{"date-parts":[[2014,8,1]],"date-time":"2014-08-01T09:19:02Z","timestamp":1406884742000},"page":"18-26","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":64,"special_numbering":"C","title":["Disrupted structural connectivity network in treatment-naive depression"],"prefix":"10.1016","volume":"56","author":[{"given":"Zhiliang","family":"Long","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xujun","family":"Duan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yifeng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing-ping","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huafu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.pnpbp.2014.07.007_bb0005","doi-asserted-by":"crossref","first-page":"e17","DOI":"10.1371\/journal.pcbi.0030017","article-title":"Efficiency and cost of economical brain functional networks","volume":"3","author":"Achard","year":"2007","journal-title":"PLoS Comput Biol"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0010","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.pscychresns.2008.03.012","article-title":"Resting state corticolimbic connectivity abnormalities in unmedicated bipolar disorder and unipolar depression","volume":"171","author":"Anand","year":"2009","journal-title":"Psychiatry Res Neuroimaging"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0015","doi-asserted-by":"crossref","first-page":"4307","DOI":"10.1523\/JNEUROSCI.5061-11.2012","article-title":"Topologically convergent and divergent structural connectivity patterns between patients with remitted geriatric depression and amnestic mild cognitive impairment","volume":"32","author":"Bai","year":"2012","journal-title":"J Neurosci"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0020","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1093\/cercor\/bhq153","article-title":"Orbitofrontal contributions to human working memory","volume":"21","author":"Barbey","year":"2011","journal-title":"Cereb Cortex"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0025","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/S0006-3223(01)01336-1","article-title":"Reduced volume of orbitofrontal cortex in major depression","volume":"51","author":"Bremner","year":"2002","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0030","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1146\/annurev-clinpsy-040510-143934","article-title":"Brain graphs: graphical models of the human brain connectome","volume":"7","author":"Bullmore","year":"2011","journal-title":"Annu Rev Clin Psychol"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0035","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1126\/science.1154433","article-title":"Orbitofrontal dysfunction in patients with obsessive\u2013compulsive disorder and their unaffected relatives","volume":"321","author":"Chamberlain","year":"2008","journal-title":"Science"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0040","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.biopsych.2011.09.005","article-title":"Fronto-striato-cerebellar dysregulation in adolescents with depression during motivated attention","volume":"71","author":"Chantiluke","year":"2012","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0045","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1111\/j.1399-5618.2005.00230.x","article-title":"Evidence for orbitofrontal pathology in bipolar disorder and major depression, but not in schizophrenia","volume":"7","author":"Cotter","year":"2005","journal-title":"Bipolar Disord"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0050","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1038\/nrn3027","article-title":"Neural mechanisms of the cognitive model of depression","volume":"12","author":"Disner","year":"2011","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0055","doi-asserted-by":"crossref","first-page":"e45972","DOI":"10.1371\/journal.pone.0045972","article-title":"Increased cortical-limbic anatomical network connectivity in major depression revealed by diffusion tensor imaging","volume":"7","author":"Fang","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0060","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1007\/s002219900240","article-title":"Effects of excitotoxic lesions in the ventral striatopallidal\u2013thalamocortical pathway on odor reversal learning: inability to extinguish an incorrect response","volume":"131","author":"Ferry","year":"2000","journal-title":"Exp Brain Res"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0065","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1111\/j.1469-7610.2006.01673.x","article-title":"Reward-related decision-making in pediatric major depressive disorder: an fMRI study","volume":"47","author":"Forbes","year":"2006","journal-title":"J Child Psychol Psychiatry"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0070","first-page":"22","article-title":"Network scaling effects in graph analytic studies of human resting-state FMRI data","volume":"4","author":"Fornito","year":"2010","journal-title":"Front Syst Neurosci"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0075","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.biopsych.2009.08.022","article-title":"Functional connectivity bias of the orbitofrontal cortex in drug-free patients with major depression","volume":"67","author":"Frodl","year":"2010","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0080","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1093\/cercor\/bhn102","article-title":"Mapping anatomical connectivity patterns of human cerebral cortex using in vivo diffusion tensor imaging tractography","volume":"19","author":"Gong","year":"2009","journal-title":"Cereb Cortex"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0085","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.pnpbp.2012.11.003","article-title":"Decreased interhemispheric resting-state functional connectivity in first-episode, drug-naive major depressive disorder","volume":"41","author":"Guo","year":"2013","journal-title":"Prog Neuro-Psychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0090","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.pnpbp.2013.01.010","article-title":"Abnormal resting-state cerebellar\u2013cerebral functional connectivity in treatment-resistant depression and treatment sensitive depression","volume":"44","author":"Guo","year":"2013","journal-title":"Prog Neuro-Psychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0095","doi-asserted-by":"crossref","first-page":"e159","DOI":"10.1371\/journal.pbio.0060159","article-title":"Mapping the structural core of human cerebral cortex","volume":"6","author":"Hagmann","year":"2008","journal-title":"PLoS Biol"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0105","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1111\/j.2044-8260.1967.tb00530.x","article-title":"Development of a rating scale for primary depressive illness","volume":"6","author":"Hamilton","year":"1967","journal-title":"Br J Soc Clin Psychol"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0100","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1016\/j.biopsych.2007.12.015","article-title":"Neural substrates of increased memory sensitivity for negative stimuli in major depression","volume":"63","author":"Hamilton","year":"2008","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0110","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1097\/WCO.0b013e32833aa567","article-title":"Graph theoretical modeling of brain connectivity","volume":"23","author":"He","year":"2010","journal-title":"Curr Opin Neurol"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0115","doi-asserted-by":"crossref","first-page":"2035","DOI":"10.1073\/pnas.0811168106","article-title":"Predicting human resting-state functional connectivity from structural connectivity","volume":"106","author":"Honey","year":"2009","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0120","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.pscychresns.2009.02.001","article-title":"Cortico-limbic response to personally challenging emotional stimuli after complete recovery from depression","volume":"172","author":"Hooley","year":"2009","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0125","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1176\/appi.ajp.2010.09101513","article-title":"High-field magnetic resonance imaging of suicidality in patients with major depressive disorder","volume":"167","author":"Jia","year":"2010","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0130","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.neulet.2011.08.017","article-title":"A preliminary study of the dysregulation of the resting networks in first-episode medication-naive adolescent depression","volume":"503","author":"Jin","year":"2011","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0135","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1017\/S0954579401003030","article-title":"Effects of early stress on brain structure and function: implications for understanding the relationship between child maltreatment and depression","volume":"13","author":"Kaufman","year":"2001","journal-title":"Dev Psychopathol"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0140","doi-asserted-by":"crossref","first-page":"2794","DOI":"10.1523\/JNEUROSCI.4655-08.2009","article-title":"Selective aspiration or neurotoxic lesions of orbital frontal areas 11 and 13 spared monkeys' performance on the object discrimination reversal task","volume":"29","author":"Kazama","year":"2009","journal-title":"J Neurosci"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0145","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1503\/jpn.120117","article-title":"Functional connectivity between the amygdala and prefrontal cortex in medication-naive individuals with major depressive disorder","volume":"38","author":"Kong","year":"2013","journal-title":"J Psychiatry Neurosci"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0150","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1097\/WNR.0b013e3283546264","article-title":"Mapping inter-regional connectivity of the entire cortex to characterize major depressive disorder: a whole-brain diffusion tensor imaging tractography study","volume":"23","author":"Korgaonkar","year":"2012","journal-title":"Neuroreport"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0380","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopsych.2014.02.018","article-title":"Abnormal structural networks characterize major depressive disorder: a connectome analysis","author":"Korgaonkar","year":"2014","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0160","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1038\/nrn1747","article-title":"The human orbitofrontal cortex: linking reward to hedonic experience","volume":"6","author":"Kringelbach","year":"2005","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0165","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/S0006-3223(00)01042-8","article-title":"Reduction of orbital frontal cortex volume in geriatric depression","volume":"48","author":"Lai","year":"2000","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0170","doi-asserted-by":"crossref","first-page":"198701","DOI":"10.1103\/PhysRevLett.87.198701","article-title":"Efficient behavior of small-world networks","volume":"87","author":"Latora","year":"2001","journal-title":"Phys Rev Lett"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0175","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1016\/j.pnpbp.2007.12.009","article-title":"Neural correlates of affective processing in response to sad and angry facial stimuli in patients with major depressive disorder","volume":"32","author":"Lee","year":"2008","journal-title":"Prog Neuro-Psychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0180","doi-asserted-by":"crossref","first-page":"2207","DOI":"10.1002\/hbm.20662","article-title":"Altered sleep brain functional connectivity in acutely depressed patients","volume":"30","author":"Leistedt","year":"2009","journal-title":"Hum Brain Mapp"},{"issue":"2","key":"10.1016\/j.pnpbp.2014.07.007_bb0385","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1089\/brain.2013.0211","article-title":"Handedness- and hemisphere-related differences in small-world networks: a diffusion tensor imaging tractography study","volume":"4","author":"Li","year":"2014","journal-title":"Brain Connect"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0190","doi-asserted-by":"crossref","first-page":"238","DOI":"10.3389\/fnhum.2012.00238","article-title":"The impact of poverty on the development of brain networks","volume":"6","author":"Lipina","year":"2012","journal-title":"Front Hum Neurosci"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0200","doi-asserted-by":"crossref","first-page":"e39516","DOI":"10.1371\/journal.pone.0039516","article-title":"Altered cerebellar functional connectivity with intrinsic connectivity networks in adults with major depressive disorder","volume":"7","author":"Liu","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0390","article-title":"Multivariate classification of social anxiety disorder using whole brain functional connectivity","author":"Liu","year":"2013","journal-title":"Brain Struct Funct"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0205","doi-asserted-by":"crossref","first-page":"16876","DOI":"10.1523\/JNEUROSCI.4136-10.2010","article-title":"Diffusion tensor tractography reveals abnormal topological organization in structural cortical networks in Alzheimer's disease","volume":"30","author":"Lo","year":"2010","journal-title":"J Neurosci"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0210","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1016\/j.jad.2013.03.004","article-title":"Altered brain structural connectivity in post-traumatic stress disorder: a diffusion tensor imaging tractography study","volume":"150","author":"Long","year":"2013","journal-title":"J Affect Disord"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0215","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1176\/appi.ajp.2010.10101419","article-title":"Resting-state functional connectivity in treatment-resistant depression","volume":"168","author":"Lui","year":"2011","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0220","doi-asserted-by":"crossref","first-page":"e45263","DOI":"10.1371\/journal.pone.0045263","article-title":"Resting-state functional connectivity bias of middle temporal gyrus and caudate with altered gray matter volume in major depression","volume":"7","author":"Ma","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0225","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/s00429-010-0280-y","article-title":"Cortico-basal ganglia circuitry: a review of key research and implications for functional connectivity studies of mood and anxiety disorders","volume":"215","author":"Marchand","year":"2010","journal-title":"Brain Struct Funct"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0230","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1037\/0735-7044.111.6.1273","article-title":"The olfactory thalamocortical system and odor reversal learning examined using an asymmetrical lesion paradigm in rats","volume":"111","author":"McBride","year":"1997","journal-title":"Behav Neurosci"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0395","doi-asserted-by":"crossref","first-page":"065103","DOI":"10.1103\/PhysRevE.71.065103","article-title":"Intensity and coherence of motifs in weighted complex networks","volume":"71","author":"Onnela","year":"2005","journal-title":"Phys Rev E Stat Nonlinear Soft Matter Phys"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0240","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1017\/S0033291701004305","article-title":"Treatment resistant depression and axis I co-morbidity","volume":"31","author":"Petersen","year":"2001","journal-title":"Psychol Med"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0245","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1111\/j.1749-6632.1999.tb09278.x","article-title":"Prefrontal cortical networks related to visceral function and mood","volume":"877","author":"Price","year":"1999","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0250","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.tics.2011.12.011","article-title":"Neural circuits underlying the pathophysiology of mood disorders","volume":"16","author":"Price","year":"2012","journal-title":"Trends Cogn Sci"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0260","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1016\/S0006-3223(99)00041-4","article-title":"Morphometric evidence for neuronal and glial prefrontal cell pathology in major depression","volume":"45","author":"Rajkowska","year":"1999","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0255","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.biopsych.2005.04.013","article-title":"Prominent reduction in pyramidal neurons density in the orbitofrontal cortex of elderly depressed patients","volume":"58","author":"Rajkowska","year":"2005","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0265","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/0014-4886(81)90273-9","article-title":"Effect of orbitofrontal and temporal neocortical lesions of the affiliative behavior of vervet monkeys (Cercopithecus aethiops sabaeus)","volume":"73","author":"Raleigh","year":"1981","journal-title":"Exp Neurol"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0270","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/0306-4522(90)90142-Q","article-title":"The effects of excitotoxic lesions of the basal forebrain on the acquisition, retention and serial reversal of visual discriminations in marmosets","volume":"34","author":"Roberts","year":"1990","journal-title":"Neuroscience"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0275","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1016\/j.neuroimage.2009.10.003","article-title":"Complex network measures of brain connectivity: uses and interpretations","volume":"52","author":"Rubinov","year":"2010","journal-title":"Neuroimage"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0280","doi-asserted-by":"crossref","first-page":"181","DOI":"10.3109\/10401239409149001","article-title":"Diagnostic and statistical manual of mental disorders, 3rd ed. (DSM-III), adaptive functioning in young Swedish suicides","volume":"6","author":"Runeson","year":"1994","journal-title":"Ann Clin Psychiatry"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0285","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1016\/j.neuroimage.2010.01.028","article-title":"Surface area and cortical thickness descriptors reveal different attributes of the structural human brain networks","volume":"50","author":"Sanabria-Diaz","year":"2010","journal-title":"Neuroimage"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0290","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1016\/j.neubiorev.2009.01.004","article-title":"Bipolar and major depressive disorder: neuroimaging the developmental\u2013degenerative divide","volume":"33","author":"Savitz","year":"2009","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0295","doi-asserted-by":"crossref","first-page":"2565","DOI":"10.1093\/cercor\/bhr039","article-title":"Diffusion tensor tractography reveals disrupted topological efficiency in white matter structural networks in multiple sclerosis","volume":"21","author":"Shu","year":"2011","journal-title":"Cereb Cortex"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0300","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1385\/NI:2:2:145","article-title":"The small world of the cerebral cortex","volume":"2","author":"Sporns","year":"2004","journal-title":"Neuroinformatics"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0400","series-title":"Conference proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society IEEE Engineering in Medicine and Biology Society Conference","first-page":"1419","article-title":"Graphic patterns of cortical functional connectivity of depressed patients on the basis of EEG measurements","author":"Sun","year":"2011"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0310","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.biopsych.2004.10.028","article-title":"A differential pattern of neural response toward sad versus happy facial expressions in major depressive disorder","volume":"57","author":"Surguladze","year":"2005","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0315","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1016\/j.jpsychires.2010.02.010","article-title":"Depression is associated with increased sensitivity to signals of disgust: a functional magnetic resonance imaging study","volume":"44","author":"Surguladze","year":"2010","journal-title":"J Psychiatr Res"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0320","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.pscychresns.2010.06.001","article-title":"fMRI activation in the amygdala and the orbitofrontal cortex in unmedicated subjects with major depressive disorder","volume":"183","author":"Townsend","year":"2010","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0325","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1006\/nimg.2001.0978","article-title":"Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain","volume":"15","author":"Tzourio-Mazoyer","year":"2002","journal-title":"Neuroimage"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0335","doi-asserted-by":"crossref","first-page":"15775","DOI":"10.1523\/JNEUROSCI.3539-11.2011","article-title":"Rich-club organization of the human connectome","volume":"31","author":"van den Heuvel","year":"2011","journal-title":"J Neurosci"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0330","doi-asserted-by":"crossref","first-page":"10844","DOI":"10.1523\/JNEUROSCI.2964-08.2008","article-title":"Microstructural organization of the cingulum tract and the level of default mode functional connectivity","volume":"28","author":"van den Heuvel","year":"2008","journal-title":"J Neurosci"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0405","article-title":"Diffusion toolkit: a software package for diffusion imaging data processing and tractography","volume":"3720","author":"Wang","year":"2007","journal-title":"Proc Int Soc Mag Reson Med"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0340","first-page":"16","article-title":"Graph-based network analysis of resting-state functional MRI","volume":"4","author":"Wang","year":"2010","journal-title":"Front Syst Neurosci"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0350","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1038\/30918","article-title":"Collective dynamics of \u2018small-world\u2019 networks","volume":"393","author":"Watts","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0410","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0075058","article-title":"Abnormal functional connectivity of amygdala in late-onset depression was associated with cognitive deficits","volume":"8","author":"Yue","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0360","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1016\/j.neuroimage.2010.06.041","article-title":"Network-based statistic: identifying differences in brain networks","volume":"53","author":"Zalesky","year":"2010","journal-title":"Neuroimage"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0365","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.biopsych.2011.05.018","article-title":"Disrupted brain connectivity networks in drug-naive, first-episode major depressive disorder","volume":"70","author":"Zhang","year":"2011","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0370","doi-asserted-by":"crossref","first-page":"2912","DOI":"10.1093\/brain\/awr223","article-title":"Altered functional\u2013structural coupling of large-scale brain networks in idiopathic generalized epilepsy","volume":"134","author":"Zhang","year":"2011","journal-title":"Brain"},{"key":"10.1016\/j.pnpbp.2014.07.007_bb0375","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/j.biopsych.2011.10.035","article-title":"Evidence of a dissociation pattern in resting-state default mode network connectivity in first-episode, treatment-naive major depression patients","volume":"71","author":"Zhu","year":"2012","journal-title":"Biol Psychiatry"}],"container-title":["Progress in Neuro-Psychopharmacology and Biological Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278584614001390?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278584614001390?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T10:40:19Z","timestamp":1777545619000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0278584614001390"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1]]},"references-count":75,"alternative-id":["S0278584614001390"],"URL":"https:\/\/doi.org\/10.1016\/j.pnpbp.2014.07.007","relation":{},"ISSN":["0278-5846"],"issn-type":[{"value":"0278-5846","type":"print"}],"subject":[],"published":{"date-parts":[[2015,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Disrupted structural connectivity network in treatment-naive depression","name":"articletitle","label":"Article Title"},{"value":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pnpbp.2014.07.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}