{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T02:39:42Z","timestamp":1790735982438,"version":"4.1.0"},"reference-count":58,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,7,1]],"date-time":"2015-07-01T00:00:00Z","timestamp":1435708800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,7,1]],"date-time":"2015-07-01T00:00:00Z","timestamp":1435708800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Progress in Neuro-Psychopharmacology and Biological Psychiatry"],"published-print":{"date-parts":[[2015,7]]},"DOI":"10.1016\/j.pnpbp.2015.02.009","type":"journal-article","created":{"date-parts":[[2015,2,20]],"date-time":"2015-02-20T00:16:53Z","timestamp":1424391413000},"page":"60-65","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":57,"special_numbering":"C","title":["NMDA receptor activation regulates sociability by its effect on mTOR signaling activity"],"prefix":"10.1016","volume":"60","author":[{"given":"Jessica A.","family":"Burket","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew D.","family":"Benson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy H.","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen I.","family":"Deutsch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.pnpbp.2015.02.009_bb0005","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.brainresbull.2013.10.006","article-title":"Balb\/c mice treated with D-cycloserine arouse increased social interest in conspecifics","volume":"99","author":"Benson","year":"2013","journal-title":"Brain Res Bull"},{"issue":"7","key":"10.1016\/j.pnpbp.2015.02.009_bb0010","doi-asserted-by":"crossref","first-page":"1603","DOI":"10.1038\/npp.2014.7","article-title":"Parvalbumin cell ablation of NMDA-R1 causes increased resting network excitability with associated social and self-care deficits","volume":"39","author":"Billingslea","year":"2014","journal-title":"Neuropsychopharmacol Off Publ Am Coll Neuropsychopharmacol"},{"issue":"1","key":"10.1016\/j.pnpbp.2015.02.009_bb0015","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.bbr.2006.06.025","article-title":"BALB\/c mice: low sociability and other phenotypes that may be relevant to autism","volume":"176","author":"Brodkin","year":"2007","journal-title":"Behav Brain Res"},{"issue":"2","key":"10.1016\/j.pnpbp.2015.02.009_bb0020","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1037\/0735-7044.122.2.483","article-title":"Social behavior phenotypes in fragile X syndrome, autism, and the Fmr1 knockout mouse: theoretical comment on McNaughton et al. (2008)","volume":"122","author":"Brodkin","year":"2008","journal-title":"Behav Neurosci"},{"issue":"6","key":"10.1016\/j.pnpbp.2015.02.009_bb0035","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.brainresbull.2010.08.014","article-title":"MK-801, a noncompetitive NMDA receptor antagonist, elicits circling behavior in the genetically inbred Balb\/c mouse strain","volume":"83","author":"Burket","year":"2010","journal-title":"Brain Res Bull"},{"issue":"5","key":"10.1016\/j.pnpbp.2015.02.009_bb0040","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.brainresbull.2010.07.006","article-title":"Locomotor activity of the genetically inbred Balb\/c mouse strain is suppressed by a socially salient stimulus","volume":"83","author":"Burket","year":"2010","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.pnpbp.2015.02.009_bb0025","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.brainresbull.2013.05.003","article-title":"D-Cycloserine improves sociability in the BTBR T+ Itpr3tf\/J mouse model of autism spectrum disorders with altered Ras\/Raf\/ERK1\/2 signaling","volume":"96","author":"Burket","year":"2013","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.pnpbp.2015.02.009_bb0030","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.brainresbull.2013.11.005","article-title":"Rapamycin improves sociability in the BTBR T(+)Itpr3(tf)\/J mouse model of autism spectrum disorders","volume":"100","author":"Burket","year":"2014","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.pnpbp.2015.02.009_bb0045","series-title":"The neuroscience of autism spectrum disorders","author":"Buxbaum","year":"2012"},{"key":"10.1016\/j.pnpbp.2015.02.009_bb0050","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.neuropharm.2012.11.003","article-title":"Behavioural and EEG effects of chronic rapamycin treatment in a mouse model of tuberous sclerosis complex","volume":"67","author":"Cambiaghi","year":"2013","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.pnpbp.2015.02.009_bb0055","doi-asserted-by":"crossref","first-page":"61","DOI":"10.3389\/fped.2014.00061","article-title":"New experimental treatments for core social domain in autism spectrum disorders","volume":"2","author":"Canitano","year":"2014","journal-title":"Front Pediatr"},{"issue":"12","key":"10.1016\/j.pnpbp.2015.02.009_bb0060","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1016\/j.molmed.2011.07.008","article-title":"mTOR: a pathogenic signaling pathway in developmental brain malformations","volume":"17","author":"Crino","year":"2011","journal-title":"Trends Mol Med"},{"issue":"10","key":"10.1016\/j.pnpbp.2015.02.009_bb0065","doi-asserted-by":"crossref","first-page":"1795","DOI":"10.1093\/hmg\/ddp092","article-title":"Autism-specific copy number variants further implicate the phosphatidylinositol signaling pathway and the glutamatergic synapse in the etiology of the disorder","volume":"18","author":"Cusc\u00f3","year":"2009","journal-title":"Hum Mol Genet"},{"issue":"1","key":"10.1016\/j.pnpbp.2015.02.009_bb0170","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.jpsychires.2013.10.008","article-title":"Prescriptive variables for d-cycloserine augmentation of exposure therapy for posttraumatic stress disorder","volume":"48","author":"De Kleine","year":"2014","journal-title":"J Psychiatr Res"},{"issue":"1\u20132","key":"10.1016\/j.pnpbp.2015.02.009_bb0090","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/S0091-3057(96)00347-4","article-title":"Inbred mouse strains differ in sensitivity to \u201cpopping\u201d behavior elicited by MK-801","volume":"57","author":"Deutsch","year":"1997","journal-title":"Pharmacol Biochem Behav"},{"issue":"4","key":"10.1016\/j.pnpbp.2015.02.009_bb0080","first-page":"255","article-title":"Inbred mouse strains differ in their sensitivity to an antiseizure effect of MK-801","volume":"21","author":"Deutsch","year":"1998","journal-title":"Clin Neuropharmacol"},{"issue":"1","key":"10.1016\/j.pnpbp.2015.02.009_bb0070","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.brainresbull.2010.10.006","article-title":"D-Cycloserine improves the impaired sociability of the Balb\/c mouse","volume":"84","author":"Deutsch","year":"2011","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.pnpbp.2015.02.009_bb0075","series-title":"Compr Book Autism Spectr Disord [Internet]","article-title":"Impaired sociability of the Balb\/c mouse, an animal model of autism spectrum disorders, is attenuated by NMDA receptor agonist interventions: clinical implications","author":"Deutsch","year":"2011"},{"key":"10.1016\/j.pnpbp.2015.02.009_bb0085","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.brainres.2011.12.040","article-title":"D-cycloserine improves sociability and spontaneous stereotypic behaviors in 4-week old mice","volume":"1439","author":"Deutsch","year":"2012","journal-title":"Brain Res"},{"issue":"5","key":"10.1016\/j.pnpbp.2015.02.009_bb0095","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1038\/npp.2013.317","article-title":"D-cycloserine augmentation of exposure therapy for post-traumatic stress disorder: a pilot randomized clinical trial","volume":"39","author":"Difede","year":"2014","journal-title":"Neuropsychopharmacol Off Publ Am Coll Neuropsychopharmacol"},{"key":"10.1016\/j.pnpbp.2015.02.009_bb0100","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.neuropharm.2012.05.015","article-title":"From genes to cognition in tuberous sclerosis: implications for mTOR inhibitor-based treatment approaches","volume":"68","author":"Ehninger","year":"2013","journal-title":"Neuropharmacology"},{"issue":"2","key":"10.1016\/j.pnpbp.2015.02.009_bb0105","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.molmed.2010.10.002","article-title":"Rapamycin for treating tuberous sclerosis and autism spectrum disorders","volume":"17","author":"Ehninger","year":"2011","journal-title":"Trends Mol Med"},{"key":"10.1016\/j.pnpbp.2015.02.009_bb0110","doi-asserted-by":"crossref","first-page":"47","DOI":"10.3389\/fnana.2011.00047","article-title":"The role of striatal-enriched protein tyrosine phosphatase (STEP) in cognition","volume":"5","author":"Fitzpatrick","year":"2011","journal-title":"Front Neuroanat"},{"key":"10.1016\/j.pnpbp.2015.02.009_bb0115","article-title":"Autism spectrum disorder profile in neurofibromatosis type I","volume":"5","author":"Garg","year":"2014","journal-title":"J Autism Dev Disord"},{"issue":"5","key":"10.1016\/j.pnpbp.2015.02.009_bb0120","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1093\/schbul\/sbs012","article-title":"D-cycloserine: an evolving role in learning and neuroplasticity in schizophrenia","volume":"38","author":"Goff","year":"2012","journal-title":"Schizophr Bull"},{"issue":"2\u20133","key":"10.1016\/j.pnpbp.2015.02.009_bb0125","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.schres.2008.08.012","article-title":"Once-weekly D-cycloserine effects on negative symptoms and cognition in schizophrenia: an exploratory study","volume":"106","author":"Goff","year":"2008","journal-title":"Schizophr Res"},{"issue":"7","key":"10.1016\/j.pnpbp.2015.02.009_bb0130","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1111\/j.1601-183X.2009.00504.x","article-title":"Assessment of NMDA receptor NR1 subunit hypofunction in mice as a model for schizophrenia","volume":"8","author":"Halene","year":"2009","journal-title":"Genes Brain Behav"},{"issue":"2","key":"10.1016\/j.pnpbp.2015.02.009_bb0135","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.tins.2009.11.003","article-title":"mTOR signaling: at the crossroads of plasticity, memory and disease","volume":"33","author":"Hoeffer","year":"2010","journal-title":"Trends Neurosci"},{"issue":"3","key":"10.1016\/j.pnpbp.2015.02.009_bb0140","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1523\/JNEUROSCI.4489-06.2007","article-title":"The cationic amino acid transporters CAT1 and CAT3 mediate NMDA receptor activation-dependent changes in elaboration of neuronal processes via the mammalian target of rapamycin mTOR pathway","volume":"27","author":"Huang","year":"2007","journal-title":"J Neurosci"},{"issue":"1","key":"10.1016\/j.pnpbp.2015.02.009_bb0145","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.brainresbull.2010.10.010","article-title":"D-serine improves dimensions of the sociability deficit of the genetically-inbred Balb\/c mouse strain","volume":"84","author":"Jacome","year":"2011","journal-title":"Brain Res Bull"},{"issue":"3\u20134","key":"10.1016\/j.pnpbp.2015.02.009_bb0150","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.brainresbull.2011.03.004","article-title":"D-Cycloserine enhances social exploration in the Balb\/c mouse","volume":"85","author":"Jacome","year":"2011","journal-title":"Brain Res Bull"},{"issue":"6","key":"10.1016\/j.pnpbp.2015.02.009_bb0155","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1002\/aur.218","article-title":"Genetically inbred Balb\/c mice differ from outbred Swiss Webster mice on discrete measures of sociability: relevance to a genetic mouse model of autism spectrum disorders","volume":"4","author":"Jacome","year":"2011","journal-title":"Autism Res"},{"key":"10.1016\/j.pnpbp.2015.02.009_bb0160","doi-asserted-by":"crossref","first-page":"225","DOI":"10.3389\/fnagi.2014.00225","article-title":"The effects of aging on the BTBR mouse model of autism spectrum disorder","volume":"6","author":"Jasien","year":"2014","journal-title":"Front Aging Neurosci"},{"key":"10.1016\/j.pnpbp.2015.02.009_bb0165","article-title":"Transient inhibition of the ERK pathway prevents cerebellar developmental defects and improves long-term motor functions in murine models of neurofibromatosis type 1","volume":"4","author":"Kim","year":"2015","journal-title":"eLife"},{"issue":"2","key":"10.1016\/j.pnpbp.2015.02.009_bb0175","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1007\/s00213-008-1196-6","article-title":"Mice with reduced NMDA receptor glycine affinity model some of the negative and cognitive symptoms of schizophrenia","volume":"200","author":"Labrie","year":"2008","journal-title":"Psychopharmacology (Berl)"},{"issue":"4","key":"10.1016\/j.pnpbp.2015.02.009_bb0180","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1172\/JCI37934","article-title":"The genetic and neurobiologic compass points toward common signaling dysfunctions in autism spectrum disorders","volume":"119","author":"Levitt","year":"2009","journal-title":"J Clin Invest"},{"issue":"3","key":"10.1016\/j.pnpbp.2015.02.009_bb0185","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1007\/BF02245335","article-title":"D-cycloserine enhances social behaviour in individually-housed mice in the resident-intruder test","volume":"116","author":"McAllister","year":"1994","journal-title":"Psychopharmacology (Berl)"},{"issue":"2","key":"10.1016\/j.pnpbp.2015.02.009_bb0190","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1111\/j.1601-183X.2007.00330.x","article-title":"Autism-like behavioral phenotypes in BTBR T+tf\/J mice","volume":"7","author":"McFarlane","year":"2008","journal-title":"Genes Brain Behav"},{"issue":"21","key":"10.1016\/j.pnpbp.2015.02.009_bb0200","doi-asserted-by":"crossref","first-page":"5546","DOI":"10.1523\/JNEUROSCI.5540-06.2007","article-title":"A mouse model of tuberous sclerosis: neuronal loss of Tsc1 causes dysplastic and ectopic neurons, reduced myelination, seizure activity, and limited survival","volume":"27","author":"Meikle","year":"2007","journal-title":"J Neurosci"},{"issue":"21","key":"10.1016\/j.pnpbp.2015.02.009_bb0195","doi-asserted-by":"crossref","first-page":"5422","DOI":"10.1523\/JNEUROSCI.0955-08.2008","article-title":"Response of a neuronal model of tuberous sclerosis to mammalian target of rapamycin (mTOR) inhibitors: effects on mTORC1 and Akt signaling lead to improved survival and function","volume":"28","author":"Meikle","year":"2008","journal-title":"J Neurosci"},{"issue":"1","key":"10.1016\/j.pnpbp.2015.02.009_bb0205","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1007\/s00213-005-2199-1","article-title":"N-Methyl-D-aspartate receptors as a target for improved antipsychotic agents: novel insights and clinical perspectives","volume":"179","author":"Millan","year":"2005","journal-title":"Psychopharmacology (Berl)"},{"issue":"5","key":"10.1016\/j.pnpbp.2015.02.009_bb0210","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/j.euroneuro.2014.03.008","article-title":"Negative symptoms of schizophrenia: clinical characteristics, pathophysiological substrates, experimental models and prospects for improved treatment","volume":"24","author":"Millan","year":"2014","journal-title":"Eur Neuropsychopharmacol J Eur Coll Neuropsychopharmacol"},{"issue":"4","key":"10.1016\/j.pnpbp.2015.02.009_bb0215","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1111\/j.1471-4159.2010.06835.x","article-title":"NR2B\u2013NMDA receptor-mediated increases in intracellular Ca2+ concentration regulate the tyrosine phosphatase, STEP, and ERK MAP kinase signaling","volume":"114","author":"Paul","year":"2010","journal-title":"J Neurochem"},{"issue":"1","key":"10.1016\/j.pnpbp.2015.02.009_bb0220","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1038\/nn989","article-title":"NMDA-mediated activation of the tyrosine phosphatase STEP regulates the duration of ERK signaling","volume":"6","author":"Paul","year":"2003","journal-title":"Nat Neurosci"},{"issue":"5","key":"10.1016\/j.pnpbp.2015.02.009_bb0225","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1016\/j.conb.2012.02.015","article-title":"Cellular and synaptic network defects in autism","volume":"22","author":"Pe\u00e7a","year":"2012","journal-title":"Curr Opin Neurobiol"},{"issue":"5","key":"10.1016\/j.pnpbp.2015.02.009_bb0230","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1016\/j.conb.2012.04.008","article-title":"Targeted treatment trials for tuberous sclerosis and autism: no longer a dream","volume":"22","author":"Sahin","year":"2012","journal-title":"Curr Opin Neurobiol"},{"issue":"2","key":"10.1016\/j.pnpbp.2015.02.009_bb0235","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1089\/cap.2013.0106","article-title":"Randomized placebo-controlled D-cycloserine with cognitive behavior therapy for pediatric posttraumatic stress","volume":"24","author":"Scheeringa","year":"2014","journal-title":"J Child Adolesc Psychopharmacol"},{"issue":"2","key":"10.1016\/j.pnpbp.2015.02.009_bb0240","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1523\/JNEUROSCI.3696-09.2010","article-title":"Dysregulation of mTOR signaling in fragile X syndrome","volume":"30","author":"Sharma","year":"2010","journal-title":"J Neurosci"},{"issue":"4","key":"10.1016\/j.pnpbp.2015.02.009_bb0245","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1038\/npp.2009.201","article-title":"Repetitive self-grooming behavior in the BTBR mouse model of autism is blocked by the mGluR5 antagonist MPEP","volume":"35","author":"Silverman","year":"2010","journal-title":"Neuropsychopharmacol Off Publ Am Coll Neuropsychopharmacol"},{"issue":"5","key":"10.1016\/j.pnpbp.2015.02.009_bb0250","doi-asserted-by":"crossref","first-page":"e35885","DOI":"10.1371\/journal.pone.0035885","article-title":"The interaction between early life epilepsy and autistic-like behavioral consequences: a role for the mammalian target of rapamycin (mTOR) pathway","volume":"7","author":"Talos","year":"2012","journal-title":"PLoS One"},{"issue":"7413","key":"10.1016\/j.pnpbp.2015.02.009_bb0255","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1038\/nature11310","article-title":"Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice","volume":"488","author":"Tsai","year":"2012","journal-title":"Nature"},{"issue":"3","key":"10.1016\/j.pnpbp.2015.02.009_bb0260","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1097\/WNF.0000000000000033","article-title":"A trial of D-cycloserine to treat stereotypies in older adolescents and young adults with autism spectrum disorder","volume":"37","author":"Urbano","year":"2014","journal-title":"Clin Neuropharmacol"},{"key":"10.1016\/j.pnpbp.2015.02.009_bb0265","doi-asserted-by":"crossref","DOI":"10.1176\/appi.neuropsych.13070155","article-title":"A trial of D-cycloserine to treat the social deficit in older adolescents and young adults with autism spectrum disorders","author":"Urbano","year":"2015","journal-title":"J Neuropsychiatry Clin Neurosci"},{"key":"10.1016\/j.pnpbp.2015.02.009_bb0270","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1146\/annurev.genom.5.061903.180050","article-title":"Autism as a paradigmatic complex genetic disorder","volume":"5","author":"Veenstra-Vanderweele","year":"2004","journal-title":"Annu Rev Genomics Hum Genet"},{"issue":"3","key":"10.1016\/j.pnpbp.2015.02.009_bb0275","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1176\/appi.ajp.2007.07050776","article-title":"Augmentation of behavior therapy with D-cycloserine for obsessive\u2013compulsive disorder","volume":"165","author":"Wilhelm","year":"2008","journal-title":"Am J Psychiatry"},{"issue":"1","key":"10.1016\/j.pnpbp.2015.02.009_bb0280","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1111\/j.1601-183X.2010.00582.x","article-title":"Reduced scent marking and ultrasonic vocalizations in the BTBR T+tf\/J mouse model of autism","volume":"10","author":"W\u00f6hr","year":"2011","journal-title":"Genes Brain Behav"},{"issue":"7402","key":"10.1016\/j.pnpbp.2015.02.009_bb0285","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1038\/nature11208","article-title":"Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function","volume":"486","author":"Won","year":"2012","journal-title":"Nature"},{"issue":"8","key":"10.1016\/j.pnpbp.2015.02.009_bb0290","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/j.ijdevneu.2007.09.008","article-title":"Social deficits in BTBR T+tf\/J mice are unchanged by cross-fostering with C57BL\/6J mothers","volume":"25","author":"Yang","year":"2007","journal-title":"Int J Dev Neurosci Off J Int Soc Dev Neurosci"}],"container-title":["Progress in Neuro-Psychopharmacology and Biological Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278584615000421?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278584615000421?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T19:43:13Z","timestamp":1759520593000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0278584615000421"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,7]]},"references-count":58,"alternative-id":["S0278584615000421"],"URL":"https:\/\/doi.org\/10.1016\/j.pnpbp.2015.02.009","relation":{},"ISSN":["0278-5846"],"issn-type":[{"value":"0278-5846","type":"print"}],"subject":[],"published":{"date-parts":[[2015,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"NMDA receptor activation regulates sociability by its effect on mTOR signaling activity","name":"articletitle","label":"Article Title"},{"value":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pnpbp.2015.02.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}