{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T10:36:39Z","timestamp":1773916599040,"version":"3.50.1"},"reference-count":127,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,2,1]],"date-time":"2016-02-01T00:00:00Z","timestamp":1454284800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100003176","name":"Ministerio de Educaci\u00f3n, Cultura y Deporte","doi-asserted-by":"publisher","award":["AGL2008-04892-C03-02"],"award-info":[{"award-number":["AGL2008-04892-C03-02"]}],"id":[{"id":"10.13039\/501100003176","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Progress in Neuro-Psychopharmacology and Biological Psychiatry"],"published-print":{"date-parts":[[2016,2]]},"DOI":"10.1016\/j.pnpbp.2015.08.007","type":"journal-article","created":{"date-parts":[[2015,8,18]],"date-time":"2015-08-18T02:15:25Z","timestamp":1439864125000},"page":"1-16","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"special_numbering":"C","title":["Age-dependent effects of esculetin on mood-related behavior and cognition from stressed mice are associated with restoring brain antioxidant status"],"prefix":"10.1016","volume":"65","author":[{"given":"Sagrario","family":"Mart\u00edn-Arag\u00f3n","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c1ngel","family":"Villar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juana","family":"Bened\u00ed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.pnpbp.2015.08.007_bb0005","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1017\/S0317167100013433","article-title":"Brain region specific monoamine and oxidative changes during restraint stress","volume":"39","author":"Ahmad","year":"2012","journal-title":"Can. J. Neurol. Sci."},{"issue":"1","key":"10.1016\/j.pnpbp.2015.08.007_bb0585","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1007\/s11357-011-9325-2","article-title":"A complex dietary supplement augments spatial learning, brain mass, and mitochondrial electron transport chain activity in aging mice","volume":"35","author":"Aksenov","year":"2013","journal-title":"Age (Dordr.)"},{"issue":"6","key":"10.1016\/j.pnpbp.2015.08.007_bb0015","doi-asserted-by":"crossref","first-page":"835","DOI":"10.3945\/jn.113.174649","article-title":"Grape powder supplementation prevents oxidative stress-induced anxiety-like behavior, memory impairment, and high blood pressure in rats","volume":"143","author":"Allam","year":"2013","journal-title":"J. Nutr."},{"key":"10.1016\/j.pnpbp.2015.08.007_bb0590","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.bbr.2014.03.032","article-title":"Loss of motor coordination in an aging mouse model","volume":"267","author":"Allen","year":"2014","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.pnpbp.2015.08.007_bb0025","series-title":"American Psychiatric Association, Diagnostic and Statistical Manual for Mental Disorders","author":"American Psychiatric Association","year":"2000"},{"issue":"4","key":"10.1016\/j.pnpbp.2015.08.007_bb9000","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1142\/S0219635214500253","article-title":"Cognitive effects of acute restraint stress in male albino rats and the impact of pretreatment with quetiapine versus ghrelin","volume":"13","author":"Amin","year":"2014","journal-title":"J. Integr. Neurosci."},{"issue":"6","key":"10.1016\/j.pnpbp.2015.08.007_bb0030","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1038\/nrn2648","article-title":"Stress signaling pathways that impair prefrontal cortex structure and function","volume":"10","author":"Arnsten","year":"2009","journal-title":"Nat. Rev. Neurosci."},{"issue":"8","key":"10.1016\/j.pnpbp.2015.08.007_bb0595","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1016\/j.freeradbiomed.2009.01.019","article-title":"An in vitro screening cascade to identify neuroprotective antioxidants in ALS","volume":"46","author":"Barber","year":"2009","journal-title":"Free Radic. Biol. Med."},{"issue":"1","key":"10.1016\/j.pnpbp.2015.08.007_bb0600","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/S0021-9258(19)50881-X","article-title":"A spectrophotometric method for measuring the breakdown of hydrogen peroxide by catalase","volume":"195","author":"Beers","year":"1952","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.pnpbp.2015.08.007_bb0045","doi-asserted-by":"crossref","first-page":"609421","DOI":"10.1155\/2012\/609421","article-title":"Preclinical and clinical evidence of antioxidant effects of antidepressant agents: implications for the pathophysiology of major depressive disorder","volume":"2012","author":"Behr","year":"2012","journal-title":"Oxidative Med. Cell. Longev."},{"issue":"6","key":"10.1016\/j.pnpbp.2015.08.007_bb0605","doi-asserted-by":"crossref","first-page":"628","DOI":"10.4088\/JCP.13m08454","article-title":"The efficacy of adjunctive N-acetylcysteine in major depressive disorder: a double-blind, randomized, placebo-controlled trial","volume":"75","author":"Berk","year":"2014","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.pnpbp.2015.08.007_bb0610","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0165-0327(00)00199-3","article-title":"Antioxidative enzyme activities and lipid peroxidation in major depression: alterations by antidepressant treatments","volume":"64","author":"Bilici","year":"2001","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.pnpbp.2015.08.007_bb0615","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.physbeh.2013.05.012","article-title":"Factors influencing behavior in the forced swim test","volume":"118","author":"Bogdanova","year":"2013","journal-title":"Physiol. Behav."},{"issue":"1","key":"10.1016\/j.pnpbp.2015.08.007_bb0620","first-page":"212","article-title":"Action of caffeine on the spontaneous motility of the mouse","volume":"158","author":"Boissier","year":"1965","journal-title":"Arch. Int. Pharmacodyn. Ther."},{"issue":"3","key":"10.1016\/j.pnpbp.2015.08.007_bb0630","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/0149-7634(94)00050-B","article-title":"Role of the serotonergic system in the forced swimming test","volume":"19","author":"Borsini","year":"1995","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.pnpbp.2015.08.007_bb0635","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/S0278-5846(98)00009-8","article-title":"Evaluation of efficacies of different classes of antidepressants in the forced swimming test in mice at different ages","volume":"22","author":"Bourin","year":"1998","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.pnpbp.2015.08.007_bb0640","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein\u2013dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal. Biochem."},{"issue":"3","key":"10.1016\/j.pnpbp.2015.08.007_bb0645","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1038\/sj.npp.1300282","article-title":"Stress sensitization of ethanol withdrawal-induced reduction in social interaction: inhibition by CRF-1 and benzodiazepine receptor antagonists and a 5-HT1A-receptor agonist","volume":"29","author":"Breese","year":"2004","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.pnpbp.2015.08.007_bb0650","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.expneurol.2012.10.024","article-title":"Folic acid prevents depressive-like behavior and hippocampal antioxidant imbalance induced by restraint stress in mice","volume":"40","author":"Budni","year":"2013","journal-title":"Exp. Neurol."},{"issue":"5","key":"10.1016\/j.pnpbp.2015.08.007_bb0655","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/j.neuint.2007.06.025","article-title":"Childhood and adolescent depression: why do children and adults respond differently to antidepressant drugs?","volume":"51","author":"Bylund","year":"2007","journal-title":"Neurochem. Int."},{"issue":"2\u20133","key":"10.1016\/j.pnpbp.2015.08.007_bb0660","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.ejphar.2010.06.043","article-title":"Antidepressant-like effect of scopoletin, a coumarin isolated from Polygala sabulosa (Polygalaceae) in mice: evidence for the involvement of monoaminergic systems","volume":"643","author":"Capra","year":"2010","journal-title":"Eur. J. Pharmacol."},{"issue":"8","key":"10.1016\/j.pnpbp.2015.08.007_bb0665","doi-asserted-by":"crossref","first-page":"3248","DOI":"10.1523\/JNEUROSCI.19-08-03248.1999","article-title":"Characterization of progressive motor deficits in mice transgenic for the human Huntington's disease mutation","volume":"19","author":"Carter","year":"1999","journal-title":"J. Neurosci."},{"issue":"1","key":"10.1016\/j.pnpbp.2015.08.007_bb0670","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.bbr.2008.06.027","article-title":"Age related differences in stress-induced neurobehavioral responses in rats: modulation by antioxidants and nitrergic agents","volume":"194","author":"Chakraborti","year":"2008","journal-title":"Behav. Brain Res."},{"issue":"3","key":"10.1016\/j.pnpbp.2015.08.007_bb0675","doi-asserted-by":"crossref","first-page":"259","DOI":"10.5625\/lar.2011.27.3.259","article-title":"Esculetin inhibits N-methyl-d-aspartate neurotoxicity via glutathione preservation in primary cortical cultures","volume":"27","author":"Chang-Ryul","year":"2011","journal-title":"Lab. Anim. Res."},{"issue":"11","key":"10.1016\/j.pnpbp.2015.08.007_bb0680","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1038\/sj.mp.4001863","article-title":"Cellular and molecular mechanisms of hippocampal activation by acute stress are age-dependent","volume":"11","author":"Chen","year":"2006","journal-title":"Mol. Psychiatry"},{"issue":"10","key":"10.1016\/j.pnpbp.2015.08.007_bb0685","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1093\/gerona\/glt030","article-title":"Increased muscle force production and bone mineral density in ActRIIB-Fc-treated mature rodents","volume":"68","author":"Chiu","year":"2013","journal-title":"J. Gerontol. A Biol. Sci. Med. Sci."},{"issue":"2","key":"10.1016\/j.pnpbp.2015.08.007_bb0690","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1080\/10253890701560119","article-title":"Evaluation of effects of previous exposure to an acute stressor before testing for depression-like behaviours in mice","volume":"11","author":"Chourbaji","year":"2008","journal-title":"Stress"},{"issue":"2","key":"10.1016\/j.pnpbp.2015.08.007_bb0695","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1007\/BF00404370","article-title":"Exploratory behavior in chronic disulfoton poisoning in mice","volume":"20","author":"Clark","year":"1971","journal-title":"Psychopharmacologia"},{"key":"10.1016\/j.pnpbp.2015.08.007_bb0700","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.pnpbp.2013.05.002","article-title":"A proposal for refining the forced swim test in Swiss mice","volume":"45","author":"Costa","year":"2013","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.pnpbp.2015.08.007_bb9005","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.bbi.2012.12.017","article-title":"Microglial activation, increased TNF and SERT expression in the prefrontal cortex define stress-altered behaviour in mice susceptible to anhedonia","volume":"29","author":"Couch","year":"2013","journal-title":"Brain Behav. Immun."},{"issue":"1","key":"10.1016\/j.pnpbp.2015.08.007_bb0705","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/S0006-8993(98)01258-X","article-title":"Behavioral phenotyping of transgenic and knockout mice: experimental design and evaluation of general health, sensory functions, motor abilities, and specific behavioral tests","volume":"835","author":"Crawley","year":"1999","journal-title":"Brain Res."},{"issue":"3","key":"10.1016\/j.pnpbp.2015.08.007_bb0710","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0014-2999(01)01628-4","article-title":"Noradrenergic lesions differentially alter the antidepressant-like effects of reboxetine in a modified forced swim test","volume":"436","author":"Cryan","year":"2002","journal-title":"Eur. J. Pharmacol."},{"issue":"3","key":"10.1016\/j.pnpbp.2015.08.007_bb0720","first-page":"325","article-title":"Effects of lipid peroxidation on neurotransmitters uptake by rat synaptosomes","volume":"37","author":"Dabrowiecki","year":"1985","journal-title":"Pol. J. Pharmacol. Pharm."},{"issue":"e2609","key":"10.1016\/j.pnpbp.2015.08.007_bb0170","article-title":"Measuring motor coordination in mice","volume":"75","author":"Deacon","year":"2013","journal-title":"J. Vis. Exp."},{"issue":"4","key":"10.1016\/j.pnpbp.2015.08.007_bb0725","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1080\/03610738108259823","article-title":"Age-related differences in behavior across the life span of the C57BL\/6J mouse","volume":"7","author":"Dean","year":"1981","journal-title":"Exp. Aging Res."},{"key":"10.1016\/j.pnpbp.2015.08.007_bb0730","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1196\/annals.1308.057","article-title":"Age-related differences in elevated plus maze behavior between adolescent and adult rats","volume":"1021","author":"Doremus","year":"2004","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.pnpbp.2015.08.007_bb0185","doi-asserted-by":"crossref","first-page":"940830","DOI":"10.1155\/2013\/940830","article-title":"Pomegranate supplementation improves affective and motor behavior in mice after radiation exposure","volume":"2013","author":"Dulcich","year":"2013","journal-title":"Evid. Based Complement. Alternat. Med."},{"issue":"2","key":"10.1016\/j.pnpbp.2015.08.007_bb0735","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1136\/ard.60.2.158","article-title":"Esculetin inhibits cartilage resorption induced by interleukin 1alpha in combination with oncostatin M","volume":"60","author":"Elliott","year":"2001","journal-title":"Ann. Rheum. Dis."},{"issue":"10","key":"10.1016\/j.pnpbp.2015.08.007_bb0740","doi-asserted-by":"crossref","first-page":"4765","DOI":"10.1073\/pnas.93.10.4765","article-title":"Age-related losses of cognitive function and motor skills in mice are associated with oxidative protein damage in the brain","volume":"93","author":"Forster","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.pnpbp.2015.08.007_bb0205","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.pneurobio.2012.01.007","article-title":"Dissecting the age-related decline on spatial learning and memory tasks in rodent models: N-methyl-d-aspartate receptors and voltage-dependent Ca2+ channels in senescent synaptic plasticity","volume":"96","author":"Foster","year":"2012","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.pnpbp.2015.08.007_bb0745","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.pnpbp.2013.12.012","article-title":"Agmatine abolishes restraint stress-induced depressive-like behavior and hippocampal antioxidant imbalance in mice","volume":"50","author":"Freitas","year":"2014","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"issue":"1","key":"10.1016\/j.pnpbp.2015.08.007_bb0750","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.neulet.2010.11.001","article-title":"Effects of a constant light environment on hippocampal neurogenesis and memory in mice","volume":"488","author":"Fujioka","year":"2011","journal-title":"Neurosci. Lett."},{"issue":"2","key":"10.1016\/j.pnpbp.2015.08.007_bb0755","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1177\/0891988714522697","article-title":"Depressive symptoms and longitudinal changes in cognition: Women's Health Initiative Study of Cognitive Aging","volume":"27","author":"Goveas","year":"2014","journal-title":"J. Geriatr. Psychiatry Neurol."},{"issue":"1","key":"10.1016\/j.pnpbp.2015.08.007_bb0760","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/0003-2697(80)90139-6","article-title":"Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine","volume":"106","author":"Griffith","year":"1980","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.pnpbp.2015.08.007_bb0765","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.neulet.2014.04.004","article-title":"Cognitive improvement of mice induced by exercise prior to traumatic brain injury is associated with cytochrome c oxidase","volume":"570","author":"Gu","year":"2014","journal-title":"Neurosci. Lett."},{"issue":"1","key":"10.1016\/j.pnpbp.2015.08.007_bb0770","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1097\/MCO.0000000000000134","article-title":"Glutathione redox imbalance in brain disorders","volume":"18","author":"Gu","year":"2015","journal-title":"Curr. Opin. Clin. Nutr. Metab. Care"},{"issue":"1\u20133","key":"10.1016\/j.pnpbp.2015.08.007_bb0775","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.ejphar.2006.04.054","article-title":"Protections of pinocembrin on brain mitochondria contribute to cognitive improvement in chronic cerebral hypoperfused rats","volume":"542","author":"Guang","year":"2006","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.pnpbp.2015.08.007_bb0780","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.neuropharm.2014.06.021","article-title":"d-serine prevents cognitive deficits induced by acute stress","volume":"86","author":"Guercio","year":"2014","journal-title":"Neuropharmacology"},{"issue":"2","key":"10.1016\/j.pnpbp.2015.08.007_bb0785","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.pbb.2008.12.010","article-title":"Differential role of nitric oxide (NO) in acute and chronic stress induced neurobehavioral modulation and oxidative injury in rats","volume":"92","author":"Gulati","year":"2009","journal-title":"Pharmacol. Biochem. Behav."},{"issue":"Pt 5","key":"10.1016\/j.pnpbp.2015.08.007_bb0790","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1042\/BST0351147","article-title":"Biochemistry of oxidative stress","volume":"35","author":"Halliwell","year":"2007","journal-title":"Biochem. Soc. Trans."},{"issue":"9","key":"10.1016\/j.pnpbp.2015.08.007_bb0795","doi-asserted-by":"crossref","first-page":"1876","DOI":"10.1016\/j.neubiorev.2011.02.016","article-title":"Mapping patterns of depression-related brain regions with cytochrome oxidase histochemistry: relevance of animal affective systems to human disorders, with a focus on resilience to adverse events","volume":"35","author":"Harro","year":"2011","journal-title":"Neurosci. Biobehav. Rev."},{"issue":"6","key":"10.1016\/j.pnpbp.2015.08.007_bb0800","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.1016\/j.biochi.2013.02.014","article-title":"Antiarthritic and antiinflammatory propensity of 4-methylesculetin, a coumarin derivative","volume":"95","author":"Hemshekhar","year":"2013","journal-title":"Biochimie"},{"issue":"7","key":"10.1016\/j.pnpbp.2015.08.007_bb0805","doi-asserted-by":"crossref","first-page":"1942","DOI":"10.1523\/JNEUROSCI.11-07-01942.1991","article-title":"Neuronal expression of nuclear and mitochondrial genes for cytochrome oxidase (CO) subunits analyzed by in situ hybridization: comparison with CO activity and protein","volume":"11","author":"Hevner","year":"1991","journal-title":"J. Neurosci."},{"issue":"1","key":"10.1016\/j.pnpbp.2015.08.007_bb0275","doi-asserted-by":"crossref","first-page":"e16646","DOI":"10.1371\/journal.pone.0016646","article-title":"Fluoxetine exerts age-dependent effects on behavior and amygdala neuroplasticity in the rat","volume":"6","author":"Homberg","year":"2011","journal-title":"PLoS One"},{"issue":"6","key":"10.1016\/j.pnpbp.2015.08.007_bb0810","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1017\/S1041610210002346","article-title":"Heterogeneity in symptom profiles among older adults diagnosed with major depression","volume":"23","author":"Hybels","year":"2011","journal-title":"Int. Psychogeriatr."},{"issue":"5","key":"10.1016\/j.pnpbp.2015.08.007_bb0815","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/0197-4580(93)90101-G","article-title":"Chronic treatment of aged mice with l-deprenyl produces marked striatal MAO-B inhibition but no beneficial effects on survival, motor performance, or nigral lipofuscin accumulation","volume":"14","author":"Ingram","year":"1993","journal-title":"Neurobiol. Aging"},{"issue":"2","key":"10.1016\/j.pnpbp.2015.08.007_bb0820","first-page":"207","article-title":"Passive avoidance in two inbred strains of mice: conditioned emotional response and specific avoidance","volume":"282","author":"Jaffard","year":"1976","journal-title":"C. R. Acad. Sci. Hebd. Seances Acad. Sci. D"},{"issue":"1","key":"10.1016\/j.pnpbp.2015.08.007_bb0825","doi-asserted-by":"crossref","first-page":"221","DOI":"10.2466\/pr0.1967.21.1.221","article-title":"An improved one-trial passive avoidance learning situation","volume":"21","author":"Jarvik","year":"1967","journal-title":"Psychol. Rep."},{"issue":"1","key":"10.1016\/j.pnpbp.2015.08.007_bb0830","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.jad.2005.10.007","article-title":"Clinical correlates of anxious depression among elderly patients with depression","volume":"90","author":"Jeste","year":"2006","journal-title":"J. Affect. Disord."},{"issue":"2","key":"10.1016\/j.pnpbp.2015.08.007_bb0305","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/BF00537801","article-title":"A rotarod suitable for quantitative measurements of motor incoordination in naive mice","volume":"259","author":"Jones","year":"1968","journal-title":"Naunyn Schmiedebergs Arch. Exp. Pathol. Pharmakol."},{"issue":"3","key":"10.1016\/j.pnpbp.2015.08.007_bb0835","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1007\/BF02690894","article-title":"The putative role of free radicals in the loss of neuronal functioning in senescence","volume":"27","author":"Joseph","year":"1992","journal-title":"Integr. Physiol. Behav. Sci."},{"issue":"6","key":"10.1016\/j.pnpbp.2015.08.007_bb0840","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1007\/s12272-012-0610-0","article-title":"Inhibitory activity of coumarins from Artemisia capillaris against advanced glycation endproduct formation","volume":"35","author":"Jung","year":"2012","journal-title":"Arch. Pharm. Res."},{"issue":"1","key":"10.1016\/j.pnpbp.2015.08.007_bb0845","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S1074-7427(02)00007-2","article-title":"Decursin from Angelica gigas mitigates amnesia induced by scopolamine in mice","volume":"79","author":"Kang","year":"2003","journal-title":"Neurobiol. Learn. Mem."},{"issue":"10","key":"10.1016\/j.pnpbp.2015.08.007_bb0850","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1016\/j.phymed.2013.03.014","article-title":"Evaluation of anti-obesity effect of Aegle marmelos leaves","volume":"20","author":"Karmase","year":"2013","journal-title":"Phytomedicine"},{"issue":"17","key":"10.1016\/j.pnpbp.2015.08.007_bb0855","doi-asserted-by":"crossref","first-page":"8206","DOI":"10.1021\/jf8014365","article-title":"Protective effects of dietary chamomile tea on diabetic complications","volume":"56","author":"Kato","year":"2008","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.pnpbp.2015.08.007_bb0860","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.jneumeth.2014.06.012","article-title":"Marble burying as a test of the delayed anxiogenic effects of acute immobilisation stress in mice","volume":"233","author":"Kedia","year":"2014","journal-title":"J. Neurosci. Methods"},{"issue":"21","key":"10.1016\/j.pnpbp.2015.08.007_bb0865","doi-asserted-by":"crossref","first-page":"1944","DOI":"10.1016\/j.lfs.2007.02.023","article-title":"Nodakenin, a coumarin compound, ameliorates scopolamine-induced memory disruption in mice","volume":"80","author":"Kim","year":"2007","journal-title":"Life Sci."},{"issue":"11","key":"10.1016\/j.pnpbp.2015.08.007_bb0870","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1111\/j.1745-7254.2008.00878.x","article-title":"Protective effect of esculetin against oxidative stress-induced cell damage via scavenging reactive oxygen species","volume":"29","author":"Kim","year":"2008","journal-title":"Acta Pharmacol. Sin."},{"issue":"Pt 1","key":"10.1016\/j.pnpbp.2015.08.007_bb0875","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.neuroimage.2013.05.070","article-title":"Cytochrome c oxidase response to changes in cerebral oxygen delivery in the adult brain shows higher brain-specificity than haemoglobin","volume":"85","author":"Kolyva","year":"2014","journal-title":"Neuroimage"},{"issue":"3","key":"10.1016\/j.pnpbp.2015.08.007_bb0880","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1089\/jmf.2006.0207","article-title":"Quercetin protects against acute immobilization stress-induced behaviors and biochemical alterations in mice","volume":"11","author":"Kumar","year":"2008","journal-title":"J. Med. Food"},{"key":"10.1016\/j.pnpbp.2015.08.007_bb0360","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/1472-6882-10-18","article-title":"Effect of St. John's Wort (Hypericum perforatum) treatment on restraint stress-induced behavioral and biochemical alteration in mice","volume":"10","author":"Kumar","year":"2010","journal-title":"BMC Complement. Altern. Med."},{"issue":"30","key":"10.1016\/j.pnpbp.2015.08.007_bb0885","doi-asserted-by":"crossref","first-page":"3797","DOI":"10.2174\/1381612043382693","article-title":"Studies on coumarins and coumarin-related compounds to determine their therapeutic role in the treatment of cancer","volume":"10","author":"Lacy","year":"2004","journal-title":"Curr. Pharm. Des."},{"issue":"4","key":"10.1016\/j.pnpbp.2015.08.007_bb0890","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1016\/0006-291X(76)90747-6","article-title":"Glutathione peroxidase activity in selenium-deficient rat liver","volume":"71","author":"Lawrence","year":"1976","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.pnpbp.2015.08.007_bb0895","doi-asserted-by":"crossref","first-page":"259","DOI":"10.5625\/lar.2011.27.3.259","article-title":"Esculetin inhibits N-methyl-d-aspartate neurotoxicity via glutathione preservation in primary cortical cultures","volume":"27","author":"Lee","year":"2011","journal-title":"Lab. Anim. Res."},{"issue":"2","key":"10.1016\/j.pnpbp.2015.08.007_bb0900","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1016\/j.gene.2013.05.069","article-title":"A current review of molecular mechanisms regarding osteoarthritis and pain","volume":"527","author":"Lee","year":"2013","journal-title":"Gene"},{"issue":"1\u20132","key":"10.1016\/j.pnpbp.2015.08.007_bb0905","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.pain.2009.02.024","article-title":"The impact of age on emotional and cognitive behaviours triggered by experimental neuropathy in rats","volume":"144","author":"Leite-Almeida","year":"2009","journal-title":"Pain"},{"issue":"14","key":"10.1016\/j.pnpbp.2015.08.007_bb0910","doi-asserted-by":"crossref","first-page":"8526","DOI":"10.1073\/pnas.1332809100","article-title":"Reversal of age-related learning deficits and brain oxidative stress in mice with superoxide dismutase\/catalase mimetics","volume":"100","author":"Liu","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"1","key":"10.1016\/j.pnpbp.2015.08.007_bb0915","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/0014-2999(76)90270-3","article-title":"Automatic registration of behaviour related to dopamine and noradrenaline transmission","volume":"36","author":"Ljungberg","year":"1976","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.pnpbp.2015.08.007_bb0920","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/j.jad.2014.06.001","article-title":"Curcumin for the treatment of major depression: a randomised, double-blind, placebo controlled study","volume":"167","author":"Lopresti","year":"2014","journal-title":"J. Affect. Disord."},{"issue":"3","key":"10.1016\/j.pnpbp.2015.08.007_bb0925","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1111\/j.1432-1033.1974.tb03714.x","article-title":"Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase","volume":"47","author":"Marklund","year":"1974","journal-title":"Eur. J. Biochem."},{"issue":"Suppl. 1","key":"10.1016\/j.pnpbp.2015.08.007_bb0930","first-page":"S75","article-title":"Oxygen active species-scavenger properties of coumarins","volume":"10","author":"Mart\u00edn-Arag\u00f3n","year":"1996","journal-title":"Phytother. Res."},{"issue":"1","key":"10.1016\/j.pnpbp.2015.08.007_bb0935","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1159\/000021978","article-title":"Effects of the antioxidant (6,7-dihydroxycoumarin) esculetin on the glutathione system and lipid peroxidation in mice","volume":"44","author":"Mart\u00edn-Arag\u00f3n","year":"1998","journal-title":"Gerontology"},{"issue":"2\u20133","key":"10.1016\/j.pnpbp.2015.08.007_bb0940","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.ejphar.2008.11.010","article-title":"Differential sensitivity to SSRI and tricyclic antidepressants in juvenile and adult mice of three strains","volume":"602","author":"Mason","year":"2009","journal-title":"Eur. J. Pharmacol."},{"issue":"11","key":"10.1016\/j.pnpbp.2015.08.007_bb0945","doi-asserted-by":"crossref","first-page":"4470","DOI":"10.1016\/S0021-9258(18)97085-7","article-title":"On the reaction mechanism of yeast glutathione reductase","volume":"240","author":"Massey","year":"1965","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.pnpbp.2015.08.007_bb0950","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/0531-5565(78)90049-9","article-title":"Simple technique for evaluation of vitality loss in aging mice, by testing their muscular coordination and vigor","volume":"13","author":"Miquel","year":"1978","journal-title":"Exp. Gerontol."},{"issue":"26","key":"10.1016\/j.pnpbp.2015.08.007_bb0955","doi-asserted-by":"crossref","first-page":"9371","DOI":"10.1073\/pnas.0504011102","article-title":"Stress duration modulates the spatiotemporal patterns of spine formation in the basolateral amygdala","volume":"102","author":"Mitra","year":"2005","journal-title":"PNAS"},{"issue":"1","key":"10.1016\/j.pnpbp.2015.08.007_bb0960","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1007\/s12031-012-9892-4","article-title":"Protective effects of ascorbic acid on behavior and oxidative status of restraint-stressed mice","volume":"49","author":"Moretti","year":"2013","journal-title":"J. Mol. Neurosci."},{"key":"10.1016\/j.pnpbp.2015.08.007_bb0445","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1038\/nrn3200","article-title":"The ageing cortical synapse: hallmarks and implications for cognitive decline","volume":"13","author":"Morrison","year":"2012","journal-title":"Nat. Rev. Neurosci."},{"issue":"5","key":"10.1016\/j.pnpbp.2015.08.007_bb0965","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1016\/j.neurobiolaging.2011.09.022","article-title":"Brain regional angiogenic potential at the neurovascular unit during normal aging","volume":"33","author":"Murugesan","year":"2012","journal-title":"Neurobiol. Aging"},{"issue":"1","key":"10.1016\/j.pnpbp.2015.08.007_bb0970","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1124\/jpet.106.115121","article-title":"Circadian-dependent learning and memory enhancement in nociceptin receptor-deficient mice with a novel KUROBOX apparatus using stress-free positive cue task","volume":"321","author":"Nagai","year":"2007","journal-title":"J. Pharmacol. Exp. Ther."},{"issue":"3","key":"10.1016\/j.pnpbp.2015.08.007_bb0975","first-page":"105","article-title":"Behavioral assessment of antidepressants (1)\u2014the forced swimming test: a review of its theory and practical application","volume":"12","author":"Naitoh","year":"1992","journal-title":"Yakubutsu Seishin Kodo"},{"issue":"1","key":"10.1016\/j.pnpbp.2015.08.007_bb0980","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1037\/0882-7974.8.1.81","article-title":"Activity memory and aging: the role of motor retrieval and strategic processing","volume":"8","author":"Norris","year":"1993","journal-title":"Psychol. Aging"},{"issue":"4","key":"10.1016\/j.pnpbp.2015.08.007_bb0985","first-page":"387","article-title":"Brain imaging for oxidative stress and mitochondrial dysfunction in neurodegenerative diseases","volume":"58","author":"Okazawa","year":"2014","journal-title":"Q. J. Nucl. Med. Mol. Imaging"},{"issue":"6","key":"10.1016\/j.pnpbp.2015.08.007_bb0990","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1016\/j.pnpbp.2010.09.013","article-title":"The age-dependent effects of selective serotonin reuptake inhibitors in humans and rodents: a review","volume":"35","author":"Olivier","year":"2011","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"issue":"2","key":"10.1016\/j.pnpbp.2015.08.007_bb0995","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1007\/s00213-002-1269-x","article-title":"Simultaneous analyses of the neurochemical and behavioral effects of the norepinephrine reuptake inhibitor reboxetine in a rat model of antidepressant action","volume":"165","author":"Page","year":"2003","journal-title":"Psychopharmacology (Berlin)"},{"issue":"1","key":"10.1016\/j.pnpbp.2015.08.007_bb1000","first-page":"158","article-title":"Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase","volume":"70","author":"Paglia","year":"1967","journal-title":"J. Lab. Clin. Med."},{"issue":"10","key":"10.1016\/j.pnpbp.2015.08.007_bb0490","doi-asserted-by":"crossref","first-page":"1818","DOI":"10.1074\/mcp.M700158-MCP200","article-title":"Proteomics identification of proteins in human cortex using multidimensional separations and MALDI tandem mass spectrometer","volume":"6","author":"Pan","year":"2007","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1016\/j.pnpbp.2015.08.007_bb1005","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.pnpbp.2012.10.017","article-title":"Antioxidants as potential therapeutics for neuropsychiatric disorders","volume":"46","author":"Pandya","year":"2013","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"issue":"1\u20132","key":"10.1016\/j.pnpbp.2015.08.007_bb1010","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/s11010-012-1342-7","article-title":"Esculetin promotes type I procollagen expression in human dermal fibroblasts through MAPK and PI3K\/Akt pathways","volume":"368","author":"Park","year":"2012","journal-title":"Mol. Cell. Biochem."},{"issue":"6","key":"10.1016\/j.pnpbp.2015.08.007_bb0505","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/j.nutres.2015.05.005","article-title":"Grape powder treatment prevents anxiety-like behavior in a rat model of aging","volume":"35","author":"Patki","year":"2015","journal-title":"Nutr. Res."},{"issue":"21","key":"10.1016\/j.pnpbp.2015.08.007_bb1015","doi-asserted-by":"crossref","first-page":"3884","DOI":"10.2174\/1381612811319210013","article-title":"Current developments of coumarin compounds in medicinal chemistry","volume":"19","author":"Peng","year":"2013","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.pnpbp.2015.08.007_bb0515","doi-asserted-by":"crossref","first-page":"153","DOI":"10.3389\/fnsys.2014.00153","article-title":"Effects of non-pharmacological or pharmacological interventions on cognition and brain plasticity of aging individuals","volume":"8","author":"Pieramico","year":"2014","journal-title":"Front. Syst. Neurosci."},{"key":"10.1016\/j.pnpbp.2015.08.007_bb1020","first-page":"746","article-title":"Immobility stress induces depression-like behavior in the forced swim test in mice: effect of magnesium and imipramine","volume":"58","author":"Poleszak","year":"2006","journal-title":"Pharmacol. Rep."},{"issue":"2","key":"10.1016\/j.pnpbp.2015.08.007_bb1025","first-page":"327","article-title":"Behavioral despair in mice: a primary screening test for antidepressants","volume":"229","author":"Porsolt","year":"1977","journal-title":"Arch. Int. Pharmacodyn. Ther."},{"issue":"9","key":"10.1016\/j.pnpbp.2015.08.007_bb1030","doi-asserted-by":"crossref","first-page":"636","DOI":"10.3109\/00207454.2013.785542","article-title":"Naringin protects memory impairment and mitochondrial oxidative damage against aluminum-induced neurotoxicity in rats","volume":"123","author":"Prakash","year":"2013","journal-title":"Int. J. Neurosci."},{"issue":"6\u20138","key":"10.1016\/j.pnpbp.2015.08.007_bb1035","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/j.neuint.2008.09.012","article-title":"Inhibition of mitochondrial respiratory chain in brain of rats subjected to an experimental model of depression","volume":"53","author":"Rezin","year":"2008","journal-title":"Neurochem. Int."},{"issue":"4","key":"10.1016\/j.pnpbp.2015.08.007_bb1040","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.jbtep.2013.03.002","article-title":"Cognitive vulnerability to anxiety in the stress generation process: further investigation of the interaction effect between the looming cognitive style and anxiety sensitivity","volume":"44","author":"Riskind","year":"2013","journal-title":"J. Behav. Ther. Exp. Psychiatry"},{"key":"10.1016\/j.pnpbp.2015.08.007_bb1045","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.bbr.2013.07.009","article-title":"Antidepressant-like responses in the forced swimming test elicited by glutathione and redox modulation","volume":"253","author":"Rosa","year":"2013","journal-title":"Behav. Brain Res."},{"issue":"6","key":"10.1016\/j.pnpbp.2015.08.007_bb1050","doi-asserted-by":"crossref","first-page":"477","DOI":"10.2165\/11633190-000000000-00000","article-title":"Antioxidants as antidepressants: fact or fiction?","volume":"26","author":"Scapagnini","year":"2012","journal-title":"CNS Drugs"},{"issue":"2","key":"10.1016\/j.pnpbp.2015.08.007_bb1055","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.jneumeth.2010.03.026","article-title":"A rotarod test for evaluation of motor skill learning","volume":"189","author":"Shiotsuki","year":"2010","journal-title":"J. Neurosci. Methods"},{"issue":"6","key":"10.1016\/j.pnpbp.2015.08.007_bb1065","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/S0531-5565(99)00039-X","article-title":"The effects of dietary antioxidants on psychomotor performance in aged mice","volume":"34","author":"Shukitt-Hale","year":"1999","journal-title":"Exp. Gerontol."},{"issue":"6","key":"10.1016\/j.pnpbp.2015.08.007_bb1070","doi-asserted-by":"crossref","first-page":"1558","DOI":"10.1016\/S1734-1140(13)71517-2","article-title":"Oxidative stress markers in affective disorders","volume":"65","author":"Siwek","year":"2013","journal-title":"Pharmacol. Rep."},{"key":"10.1016\/j.pnpbp.2015.08.007_bb1075","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1002\/9780470110188.ch13","article-title":"Spectrophotometric assay of cytochrome c oxidase","volume":"2","author":"Smith","year":"1955","journal-title":"Methods Biochem. Anal."},{"issue":"1","key":"10.1016\/j.pnpbp.2015.08.007_bb0580","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.nutres.2014.11.008","article-title":"Grape powder prevents cognitive, behavioral, and biochemical impairments in a rat model of posttraumatic stress disorder","volume":"35","author":"Solanki","year":"2015","journal-title":"Nutr. Res."},{"issue":"3","key":"10.1016\/j.pnpbp.2015.08.007_bb1080","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1002\/jnr.23164","article-title":"Neuroprotective effects of umbelliferone and esculetin in a mouse model of Parkinson's disease","volume":"91","author":"Subramaniam","year":"2013","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.pnpbp.2015.08.007_bb1085","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/0006-8993(80)90981-6","article-title":"Intracellular brain pH and the pathway of a fat soluble pH indicator across the blood\u2013brain barrier","volume":"186(2)","author":"Sundt","year":"1980","journal-title":"Brain Res."},{"issue":"1","key":"10.1016\/j.pnpbp.2015.08.007_bb1090","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.etap.2014.04.028","article-title":"Viola mandshurica ethanolic extract prevents high-fat-diet-induced obesity in mice by activating AMP-activated protein kinase","volume":"38","author":"Sung","year":"2014","journal-title":"Environ. Toxicol. Pharmacol."},{"issue":"1","key":"10.1016\/j.pnpbp.2015.08.007_bb1095","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S0014-2999(98)00223-4","article-title":"Changes in head-dipping behavior in the hole-board test reflect the anxiogenic and\/or anxiolytic state in mice","volume":"350","author":"Takeda","year":"1998","journal-title":"Eur. J. Pharmacol."},{"issue":"3","key":"10.1016\/j.pnpbp.2015.08.007_bb1100","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/0003-2697(69)90064-5","article-title":"Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues","volume":"27","author":"Tietze","year":"1969","journal-title":"Anal. Biochem."},{"issue":"1","key":"10.1016\/j.pnpbp.2015.08.007_bb1105","first-page":"99","article-title":"Assaying for maximal cytochrome c oxidase activity in fish muscle","volume":"5","author":"Tyler","year":"1995","journal-title":"BAM"},{"key":"10.1016\/j.pnpbp.2015.08.007_bb1110","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.biocel.2006.07.001","article-title":"Free radicals and antioxidants in normal physiological functions and human disease","volume":"39","author":"Valko","year":"2007","journal-title":"Int. J. Biochem. Cell Biol."},{"issue":"1","key":"10.1016\/j.pnpbp.2015.08.007_bb1115","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0166-4328(00)00240-0","article-title":"Behavioural analysis of four mouse strains in an anxiety test battery","volume":"115","author":"Van Gaalen","year":"2000","journal-title":"Behav. Brain Res."},{"issue":"6","key":"10.1016\/j.pnpbp.2015.08.007_bb1120","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1111\/j.1471-4159.2012.07744.x","article-title":"A natural coumarin derivative esculetin offers neuroprotection on cerebral ischemia\/reperfusion injury in mice","volume":"121","author":"Wang","year":"2012","journal-title":"J. Neurochem."},{"issue":"3","key":"10.1016\/j.pnpbp.2015.08.007_bb1125","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/0091-3057(81)90273-2","article-title":"Locomotor activity in morphine-treated rats: effects of and comparisons between cocaine, procaine, and lidocaine","volume":"15","author":"Wiechman","year":"1981","journal-title":"Pharmacol. Biochem. Behav."},{"issue":"2","key":"10.1016\/j.pnpbp.2015.08.007_bb1130","doi-asserted-by":"crossref","first-page":"108","DOI":"10.2174\/1570159X11666131120231448","article-title":"Novel therapeutic targets in depression and anxiety: antioxidants as a candidate treatment","volume":"12","author":"Xu","year":"2014","journal-title":"Curr. Neuropharmacol."},{"issue":"2","key":"10.1016\/j.pnpbp.2015.08.007_bb1135","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.pnpbp.2008.11.010","article-title":"In vivo antioxidant status: a putative target of antidepressant action","volume":"33","author":"Zafir","year":"2009","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"issue":"5","key":"10.1016\/j.pnpbp.2015.08.007_bb1140","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1017\/S1461145713001661","article-title":"Effects of curcumin on chronic, unpredictable, mild, stress-induced depressive-like behaviour and structural plasticity in the lateral amygdala of rats","volume":"17","author":"Zhang","year":"2014","journal-title":"Int. J. Neuropsychopharmacol."}],"container-title":["Progress in Neuro-Psychopharmacology and Biological Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278584615300270?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278584615300270?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,10]],"date-time":"2024-06-10T15:50:41Z","timestamp":1718034641000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0278584615300270"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2]]},"references-count":127,"alternative-id":["S0278584615300270"],"URL":"https:\/\/doi.org\/10.1016\/j.pnpbp.2015.08.007","relation":{},"ISSN":["0278-5846"],"issn-type":[{"value":"0278-5846","type":"print"}],"subject":[],"published":{"date-parts":[[2016,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Age-dependent effects of esculetin on mood-related behavior and cognition from stressed mice are associated with restoring brain antioxidant status","name":"articletitle","label":"Article Title"},{"value":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pnpbp.2015.08.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}