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Neuropsychopharmacol."},{"key":"10.1016\/j.pnpbp.2017.02.020_bb0710","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/j.jpsychires.2010.07.012","article-title":"Effects of gustatory stimulation on brain activity during hunger and satiety in females with restricting-type anorexia nervosa: an fMRI study","volume":"45","author":"Vocks","year":"2011","journal-title":"J. Psychiatry Res."},{"key":"10.1016\/j.pnpbp.2017.02.020_bb9000","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1002\/cne.20512","article-title":"Architecture and neurocytology of monkey cingulate gyrus","volume":"485","author":"Vogt","year":"2005","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.pnpbp.2017.02.020_bb0715","doi-asserted-by":"crossref","first-page":"3191","DOI":"10.1098\/rstb.2008.0107","article-title":"Overlapping neuronal circuits in addiction and obesity: evidence of systems pathology","volume":"363","author":"Volkow","year":"2008","journal-title":"Philos. Trans. R. Soc. Lond. Ser. B Biol. Sci."},{"key":"10.1016\/j.pnpbp.2017.02.020_bb0720","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.tics.2010.11.001","article-title":"Reward, dopamine and the control of food intake: implications for obesity","volume":"15","author":"Volkow","year":"2011","journal-title":"Trends Cogn. Sci."},{"key":"10.1016\/j.pnpbp.2017.02.020_bb0725","doi-asserted-by":"crossref","first-page":"1842","DOI":"10.1176\/appi.ajp.2007.07040575","article-title":"Altered reward processing in women recovered from anorexia nervosa","volume":"164","author":"Wagner","year":"2007","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.pnpbp.2017.02.020_bb0730","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1038\/sj.npp.1301443","article-title":"Altered insula response to a taste stimulus in individuals recovered from restricting-type anorexia nervosa","volume":"33","author":"Wagner","year":"2008","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.pnpbp.2017.02.020_bb0735","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1002\/eat.20699","article-title":"Altered striatal response to reward in bulimia nervosa after recovery","volume":"43","author":"Wagner","year":"2010","journal-title":"Int. J. Eat. Disord."},{"key":"10.1016\/j.pnpbp.2017.02.020_bb0740","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1162\/jocn_a_00238","article-title":"Inducing negative affect increases the reward value of appetizing foods in dieters","volume":"24","author":"Wagner","year":"2012","journal-title":"J. Cogn. Neurosci."},{"key":"10.1016\/j.pnpbp.2017.02.020_bb0745","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1176\/appi.ajp.2012.12081074","article-title":"The enigmatic persistence of anorexia nervosa","volume":"170","author":"Walsh","year":"2013","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.pnpbp.2017.02.020_bb0750","doi-asserted-by":"crossref","first-page":"6475","DOI":"10.1523\/JNEUROSCI.23-16-06475.2003","article-title":"Functional specialization within medial frontal cortex of the anterior cingulate for evaluating effort-related decisions","volume":"23","author":"Walton","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.pnpbp.2017.02.020_bb0755","doi-asserted-by":"crossref","first-page":"1911","DOI":"10.1007\/s00213-016-4222-0","article-title":"A role for the endocannabinoid 2-arachidonoyl-sn-glycerol for social and high-fat food reward in male mice","volume":"233","author":"Wei","year":"2016","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.pnpbp.2017.02.020_bb0760","doi-asserted-by":"crossref","first-page":"2135","DOI":"10.1002\/hbm.21345","article-title":"Diagnosing different binge-eating disorders based on reward-related brain activation patterns","volume":"33","author":"Weygandt","year":"2012","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.pnpbp.2017.02.020_bb0765","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/S0896-6273(02)00965-0","article-title":"Brain reward circuitry, insights from unsensed incentives","volume":"36","author":"Wise","year":"2002","journal-title":"Neuron"},{"key":"10.1016\/j.pnpbp.2017.02.020_bb0770","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1037\/a0017252","article-title":"Now or later? Striatum and insula activation to immediate versus delayed rewards","volume":"3","author":"Wittman","year":"2010","journal-title":"J. Neurosci. Psychol. 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