{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,11]],"date-time":"2026-11-11T21:42:24Z","timestamp":1794433344861,"version":"4.9.1"},"reference-count":53,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100013327","name":"H. Lundbeck A\/S","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013327","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Progress in Neuro-Psychopharmacology and Biological Psychiatry"],"published-print":{"date-parts":[[2021,8]]},"DOI":"10.1016\/j.pnpbp.2021.110285","type":"journal-article","created":{"date-parts":[[2021,2,18]],"date-time":"2021-02-18T19:10:42Z","timestamp":1613675442000},"page":"110285","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":41,"special_numbering":"C","title":["Melancholic features in major depression \u2013 a European multicenter study"],"prefix":"10.1016","volume":"110","author":[{"given":"Markus","family":"Dold","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucie","family":"Bartova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gernot","family":"Fugger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Kautzky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marleen M.M.","family":"Mitschek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Fabbri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stuart","family":"Montgomery","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Zohar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Souery","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julien","family":"Mendlewicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Serretti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siegfried","family":"Kasper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.pnpbp.2021.110285_bb0005","series-title":"Diagnostic and Statistical Manual of Mental Disorders","author":"APA","year":"2013"},{"key":"10.1016\/j.pnpbp.2021.110285_bb0010","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1176\/appi.ajp.2015.14020181","article-title":"Depression subtypes in predicting antidepressant response: a report from the iSPOT-D trial","volume":"172","author":"Arnow","year":"2015","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.pnpbp.2021.110285_bb0015","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1080\/15622975.2019.1635270","article-title":"Results of the European Group for the Study of Resistant Depression (GSRD) - basis for further research and clinical practice","volume":"20","author":"Bartova","year":"2019","journal-title":"World J. Biol. Psychiatry"},{"key":"10.1016\/j.pnpbp.2021.110285_bb0020","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/13651501.2017.1306082","article-title":"Pharmacological treatment of unipolar depressive disorders: summary of WFSBP guidelines","volume":"21","author":"Bauer","year":"2017","journal-title":"Int. J. Psychiatry Clin. Pract."},{"key":"10.1016\/j.pnpbp.2021.110285_bb0025","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.jad.2011.04.032","article-title":"Randomized comparison of selective serotonin reuptake inhibitor (escitalopram) monotherapy and antidepressant combination pharmacotherapy for major depressive disorder with melancholic features: a CO-MED report","volume":"133","author":"Bobo","year":"2011","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.pnpbp.2021.110285_bb0030","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1111\/j.1600-0447.2007.00970.x","article-title":"Treatment response in melancholia","author":"Brown","year":"2007","journal-title":"Acta Psychiatr. Scand. Suppl."},{"key":"10.1016\/j.pnpbp.2021.110285_bb0035","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/j.pnpbp.2010.10.019","article-title":"Psychomotor retardation in depression: biological underpinnings, measurement, and treatment","volume":"35","author":"Buyukdura","year":"2011","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.pnpbp.2021.110285_bb0040","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.comppsych.2012.05.012","article-title":"Clinical differences between melancholic and nonmelancholic depression as defined by the CORE system","volume":"54","author":"Caldieraro","year":"2013","journal-title":"Compr. Psychiatry"},{"key":"10.1016\/j.pnpbp.2021.110285_bb0045","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1097\/NMD.0b013e3182a5c06e","article-title":"Prevalence of psychotic symptoms in those with melancholic and nonmelancholic depression","volume":"201","author":"Caldieraro","year":"2013","journal-title":"J. Nerv. Ment. Dis."},{"key":"10.1016\/j.pnpbp.2021.110285_bb0050","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1124\/pr.117.014977","article-title":"International union of basic and clinical pharmacology CIV: the neurobiology of treatment-resistant depression: from antidepressant classifications to novel pharmacological targets","volume":"70","author":"Caraci","year":"2018","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.pnpbp.2021.110285_bb0055","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1080\/09540261.2020.1765748","article-title":"Relative effectiveness of augmentation treatments for treatment-resistant depression","volume":"32","author":"Carter","year":"2020","journal-title":"Int. Rev. Psychiatry"},{"key":"10.1016\/j.pnpbp.2021.110285_bb0060","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1177\/0269881115581093","article-title":"Evidence-based guidelines for treating depressive disorders with antidepressants: a revision of the 2008 British Association for Psychopharmacology guidelines","volume":"29","author":"Cleare","year":"2015","journal-title":"J. Psychopharmacol."},{"key":"10.1016\/j.pnpbp.2021.110285_bb0065","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1002\/da.22580","article-title":"Melancholic and atypical depression as predictor and moderator of outcome in cognitive behavior therapy and pharmacotherapy for adult depression","volume":"34","author":"Cuijpers","year":"2017","journal-title":"Depress. Anxiety"},{"key":"10.1016\/j.pnpbp.2021.110285_bb0070","first-page":"131","article-title":"Citalopram: clinical effect profile in comparison with clomipramine: a controlled multicenter study","volume":"90","author":"Danish University Antidepressant Group","year":"1986","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.pnpbp.2021.110285_bb0075","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1080\/13651501.2016.1248852","article-title":"Evidence-based pharmacotherapy of treatment-resistant unipolar depression","volume":"21","author":"Dold","year":"2017","journal-title":"Int. J. Psychiatry Clin. Pract."},{"key":"10.1016\/j.pnpbp.2021.110285_bb0080","doi-asserted-by":"crossref","first-page":"1960","DOI":"10.1016\/j.euroneuro.2016.10.005","article-title":"Pharmacological treatment strategies in unipolar depression in European tertiary psychiatric treatment centers - a pharmacoepidemiological cross-sectional multicenter study","volume":"26","author":"Dold","year":"2016","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.pnpbp.2021.110285_bb0085","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1016\/j.euroneuro.2018.10.003","article-title":"Clinical factors associated with augmentation treatment with second-generation antipsychotics and lithium in major depression - results from a European multicenter study","volume":"28","author":"Dold","year":"2018","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.pnpbp.2021.110285_bb0090","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1111\/acps.12870","article-title":"Clinical correlates of augmentation\/combination treatment strategies in major depressive disorder","volume":"137","author":"Dold","year":"2018","journal-title":"Acta Psychiatr. Sand."},{"key":"10.1016\/j.pnpbp.2021.110285_bb0095","doi-asserted-by":"crossref","DOI":"10.4088\/JCP.17m12090","article-title":"Psychotic features in patients with major depressive disorder: a report from the European group for the study of resistant depression","volume":"80","author":"Dold","year":"2019","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.pnpbp.2021.110285_bb0100","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.pnpbp.2012.11.009","article-title":"Melancholic and atypical major depression - connection between cytokines, psychopathology and treatment","volume":"43","author":"Dunjic-Kostic","year":"2013","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.pnpbp.2021.110285_bb0105","doi-asserted-by":"crossref","first-page":"109638","DOI":"10.1016\/j.pnpbp.2019.109638","article-title":"Major depression and comorbid diabetes - findings from the European group for the study of resistant depression","volume":"94","author":"Fugger","year":"2019","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.pnpbp.2021.110285_bb0110","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0048200","article-title":"Clinical patterns and treatment outcome in patients with melancholic, atypical and non-melancholic depressions","volume":"7","author":"Gili","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.pnpbp.2021.110285_bb0115","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1136\/jnnp.23.1.56","article-title":"A rating scale for depression","volume":"23","author":"Hamilton","year":"1960","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.pnpbp.2021.110285_bb2000","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.jad.2015.03.021","article-title":"Dose equivalents of antidepressants: evidencebased recommendations from randomized controlled trials","volume":"180","author":"Hayasaka","year":"2015","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.pnpbp.2021.110285_bb0120","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1192\/bjp.169.1.68","article-title":"Prediction of ECT response: validation of a refined sign-based (CORE) system for defining melancholia","volume":"169","author":"Hickie","year":"1996","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.pnpbp.2021.110285_bb0125","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1046\/j.1440-1614.2001.01025.x","article-title":"Melancholia: definitions, risk factors, personality, neuroendocrine markers and differential antidepressant response","volume":"36","author":"Joyce","year":"2002","journal-title":"Aust. N. Z. J. Psychiatr."},{"key":"10.1016\/j.pnpbp.2021.110285_bb0130","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1034\/j.1600-0447.2003.00120.x","article-title":"A differential response to nortriptyline and fluoxetine in melancholic depression: the importance of age and gender","volume":"108","author":"Joyce","year":"2003","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/j.pnpbp.2021.110285_bb0135","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.euroneuro.2015.01.001","article-title":"The combined effect of genetic polymorphisms and clinical parameters on treatment outcome in treatment-resistant depression","volume":"25","author":"Kautzky","year":"2015","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.pnpbp.2021.110285_bb0140","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1080\/10401230600614496","article-title":"Clinical and demographic factors associated with DSM-IV melancholic depression","volume":"18","author":"Khan","year":"2006","journal-title":"Ann. Clin. Psychiatry"},{"key":"10.1016\/j.pnpbp.2021.110285_bb0145","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.cpr.2004.09.001","article-title":"The empirical status of melancholia: implications for psychology","volume":"25","author":"Leventhal","year":"2005","journal-title":"Clin. Psychol. Rev."},{"key":"10.1016\/j.pnpbp.2021.110285_bb0150","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/j.psychres.2015.11.009","article-title":"Melancholic features in inpatients with major depressive disorder associate with differential clinical characteristics and treatment outcomes","volume":"238","author":"Lin","year":"2016","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.pnpbp.2021.110285_bb0155","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.4088\/JCP.v69n1201","article-title":"Response to a selective serotonin reuptake inhibitor (citalopram) in major depressive disorder with melancholic features: a STAR*D report","volume":"69","author":"McGrath","year":"2008","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.pnpbp.2021.110285_bb0160","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1017\/S0033291704002806","article-title":"Co-morbidity and stability of melancholic features in DSM-IV major depressive disorder","volume":"34","author":"Melartin","year":"2004","journal-title":"Psychol. Med."},{"key":"10.1016\/j.pnpbp.2021.110285_bb0165","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1192\/bjp.134.4.382","article-title":"A new depression scale designed to be sensitive to change","volume":"134","author":"Montgomery","year":"1979","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.pnpbp.2021.110285_bb0170","doi-asserted-by":"crossref","DOI":"10.1002\/mpr.1569","article-title":"Subtypes of depression and their overlap in a naturalistic inpatient sample of major depressive disorder","volume":"27","author":"Musil","year":"2018","journal-title":"Int. J. Methods Psychiatr. Res."},{"key":"10.1016\/j.pnpbp.2021.110285_bb0175","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1034\/j.1600-0447.2000.101001021.x","article-title":"Subtyping depression by clinical features: the Australasian database","volume":"101","author":"Parker","year":"2000","journal-title":"Acta Psychiatr. Sand."},{"key":"10.1016\/j.pnpbp.2021.110285_bb0180","doi-asserted-by":"crossref","first-page":"117","DOI":"10.4088\/JCP.v62n0209","article-title":"Assessing the comparative effectiveness of antidepressant therapies: a prospective clinical practice study","volume":"62","author":"Parker","year":"2001","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.pnpbp.2021.110285_bb0185","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.jad.2009.10.001","article-title":"Inching toward Bethlehem: mapping melancholia","volume":"123","author":"Parker","year":"2010","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.pnpbp.2021.110285_bb0190","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.jad.2012.06.042","article-title":"Discriminating melancholic and non-melancholic depression by prototypic clinical features","volume":"144","author":"Parker","year":"2013","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.pnpbp.2021.110285_bb0195","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1016\/j.comppsych.2013.02.010","article-title":"Validation of a new prototypic measure of melancholia","volume":"54","author":"Parker","year":"2013","journal-title":"Compr. Psychiatry"},{"key":"10.1016\/j.pnpbp.2021.110285_bb0200","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1111\/bdi.12501","article-title":"Defining melancholia: a core mood disorder","volume":"19","author":"Parker","year":"2017","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.pnpbp.2021.110285_bb0205","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0165-0327(96)00014-6","article-title":"Pharmacotherapy for major depression with melancholic features: relative efficacy of tricyclic versus selective serotonin reuptake inhibitor antidepressants","volume":"39","author":"Perry","year":"1996","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.pnpbp.2021.110285_bb0210","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1176\/ajp.151.12.1735","article-title":"Comparative efficacy of selective serotonin reuptake inhibitors and tricyclics in the treatment of melancholia","volume":"151","author":"Roose","year":"1994","journal-title":"Am. J. Psychiatry"},{"issue":"Suppl. 8","key":"10.1016\/j.pnpbp.2021.110285_bb0215","first-page":"4","article-title":"The varied clinical presentations of major depressive disorder","volume":"68","author":"Rush","year":"2007","journal-title":"J. Clin. Psychiatry"},{"issue":"Suppl. 20","key":"10.1016\/j.pnpbp.2021.110285_bb0220","first-page":"22","article-title":"The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10","volume":"59","author":"Sheehan","year":"1998","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.pnpbp.2021.110285_bb0225","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1111\/j.1600-0447.1998.tb10115.x","article-title":"Are in-patient depressives more often of the melancholic subtype? Danish University Antidepressant Group","volume":"98","author":"Stage","year":"1998","journal-title":"Acta Psychiatr. Sand."},{"key":"10.1016\/j.pnpbp.2021.110285_bb0230","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1002\/da.20875","article-title":"A comparison of melancholic and nonmelancholic recurrent major depression in Han Chinese women","volume":"29","author":"Sun","year":"2012","journal-title":"Depress. Anxiety"},{"key":"10.1016\/j.pnpbp.2021.110285_bb0235","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1016\/j.jad.2020.01.139","article-title":"Melancholic versus nonmelancholic major depression compared","volume":"266","author":"Tondo","year":"2020","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.pnpbp.2021.110285_bb0240","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.jad.2011.02.014","article-title":"Melancholic, atypical and anxious depression subtypes and outcome of treatment with escitalopram and nortriptyline","volume":"132","author":"Uher","year":"2011","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.pnpbp.2021.110285_bb0245","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1177\/0269881120953983","article-title":"Antidepressant responses in direct comparisons of melancholic and non-melancholic depression","volume":"34","author":"Undurraga","year":"2020","journal-title":"J. Psychopharmacol."},{"key":"10.1016\/j.pnpbp.2021.110285_bb0250","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.jad.2012.06.004","article-title":"Response to antidepressants in major depressive disorder with melancholic features: the CRESCEND study","volume":"144","author":"Yang","year":"2013","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.pnpbp.2021.110285_bb0255","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.jad.2016.04.039","article-title":"A meta-analysis of cognitive performance in melancholic versus non-melancholic unipolar depression","volume":"201","author":"Zaninotto","year":"2016","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.pnpbp.2021.110285_bb0260","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1001\/archpsyc.1986.01800030052005","article-title":"The validity of four definitions of endogenous depression. II. Clinical, demographic, familial, and psychosocial correlates","volume":"43","author":"Zimmerman","year":"1986","journal-title":"Arch. Gen. Psychiatry"}],"container-title":["Progress in Neuro-Psychopharmacology and Biological Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278584621000440?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278584621000440?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T19:54:26Z","timestamp":1759521266000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0278584621000440"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8]]},"references-count":53,"alternative-id":["S0278584621000440"],"URL":"https:\/\/doi.org\/10.1016\/j.pnpbp.2021.110285","relation":{},"ISSN":["0278-5846"],"issn-type":[{"value":"0278-5846","type":"print"}],"subject":[],"published":{"date-parts":[[2021,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Melancholic features in major depression \u2013 a European multicenter study","name":"articletitle","label":"Article Title"},{"value":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pnpbp.2021.110285","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"110285"}}