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Sci."},{"issue":"3","key":"10.1016\/j.pnpbp.2024.111194_bb0390","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1007\/s00406-020-01110-5","article-title":"Intravenous arketamine for treatment-resistant depression: open-label pilot study","volume":"271","author":"Leal","year":"2021","journal-title":"Eur. Arch. Psychiatry Clin. Neurosci."},{"key":"10.1016\/j.pnpbp.2024.111194_bb0395","doi-asserted-by":"crossref","first-page":"698","DOI":"10.3389\/fimmu.2018.00698","article-title":"Microglia and beyond: innate immune cells as regulators of brain development and behavioral function","volume":"9","author":"Lenz","year":"2018","journal-title":"Front. 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Neurol."},{"issue":"2","key":"10.1016\/j.pnpbp.2024.111194_bb0525","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/S0893-133X(98)00067-0","article-title":"Ketamine-induced NMDA receptor hypofunction as a model of memory impairment and psychosis","volume":"20","author":"Newcomer","year":"1999","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.pnpbp.2024.111194_bb0530","doi-asserted-by":"crossref","first-page":"169","DOI":"10.12688\/f1000research.4439.1","article-title":"Myelin-specific T helper 17 cells promote adult hippocampal neurogenesis through indirect mechanisms","volume":"3","author":"Niebling","year":"2014","journal-title":"F1000Res"},{"key":"10.1016\/j.pnpbp.2024.111194_bb0535","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.neuropharm.2015.07.034","article-title":"Positive allosteric modulators of alpha 7 nicotinic acetylcholine receptors reverse ketamine-induced schizophrenia-like deficits in rats","volume":"101","author":"Nikiforuk","year":"2016","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.pnpbp.2024.111194_bb0540","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.neuropharm.2016.01.035","article-title":"The effects of a 5-HT5A receptor antagonist in a ketamine-based rat model of cognitive dysfunction and the negative symptoms of schizophrenia","volume":"105","author":"Nikiforuk","year":"2016","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.pnpbp.2024.111194_bb0545","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.1038\/nm.3407","article-title":"Development, maintenance and disruption of the blood-brain barrier","volume":"19","author":"Obermeier","year":"2013","journal-title":"Nat. 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Behav."},{"issue":"4","key":"10.1016\/j.pnpbp.2024.111194_bb0610","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1054\/mehy.2000.1203","article-title":"The Th2-hypothesis of schizophrenia: a strategy to identify a subgroup of schizophrenia caused by immune mechanisms","volume":"56","author":"Schwarz","year":"2001","journal-title":"Med. Hypotheses"},{"issue":"s1","key":"10.1016\/j.pnpbp.2024.111194_bb0615","doi-asserted-by":"crossref","first-page":"S75","DOI":"10.3233\/JPD-223418","article-title":"B lymphocytes in Parkinson\u2019s disease","volume":"12","author":"Scott","year":"2022","journal-title":"J. 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