{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T06:56:10Z","timestamp":1788245770123,"version":"build-2803163510"},"reference-count":53,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100017534","name":"333 Project of Jiangsu Province","doi-asserted-by":"publisher","award":["2022)3\\u201329-052"],"award-info":[{"award-number":["2022)3\\u201329-052"]}],"id":[{"id":"10.13039\/501100017534","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010854","name":"Jiangsu Provincial Commission of Health and Family Planning","doi-asserted-by":"publisher","award":["M2020031"],"award-info":[{"award-number":["M2020031"]}],"id":[{"id":"10.13039\/501100010854","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010854","name":"Jiangsu Provincial Commission of Health and Family Planning","doi-asserted-by":"publisher","award":["LR2022015"],"award-info":[{"award-number":["LR2022015"]}],"id":[{"id":"10.13039\/501100010854","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010854","name":"Jiangsu Provincial Commission of Health and Family Planning","doi-asserted-by":"publisher","award":["LKZ2023020"],"award-info":[{"award-number":["LKZ2023020"]}],"id":[{"id":"10.13039\/501100010854","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017962","name":"Jiangsu Commission of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100017962","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Progress in Neuro-Psychopharmacology and Biological Psychiatry"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1016\/j.pnpbp.2025.111302","type":"journal-article","created":{"date-parts":[[2025,2,25]],"date-time":"2025-02-25T03:02:30Z","timestamp":1740452550000},"page":"111302","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Identifying periphery biomarkers of first-episode drug-na\u00efve patients with schizophrenia using machine-learning-based strategies"],"prefix":"10.1016","volume":"137","author":[{"given":"Bo","family":"Pan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueying","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianjun","family":"Weng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaofeng","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaqin","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doudou","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangrong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaowei","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.pnpbp.2025.111302_bb0005","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/0006-3223(94)91163-0","article-title":"T-cell subsets in acute psychotic schizophrenic patients","volume":"35","author":"Achiron","year":"1994","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.pnpbp.2025.111302_bb0010","doi-asserted-by":"crossref","DOI":"10.1093\/bib\/bbab128","article-title":"Machine learning approach to gene essentiality prediction: a review","volume":"22","author":"Aromolaran","year":"2021","journal-title":"Brief. Bioinform."},{"key":"10.1016\/j.pnpbp.2025.111302_bb0015","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0032618","article-title":"Marked reduction of AKT1 expression and deregulation of AKT1-associated pathways in peripheral blood mononuclear cells of schizophrenia patients","volume":"7","author":"van Beveren","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.pnpbp.2025.111302_bb0020","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1093\/schbul\/sbac089","article-title":"Neutrophil to lymphocyte ratio in patients with a first episode of psychosis: a two-year longitudinal follow-up study","volume":"48","author":"Bioque","year":"2022","journal-title":"Schizophr. Bull."},{"key":"10.1016\/j.pnpbp.2025.111302_bb0025","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1002\/ajmg.b.31006","article-title":"Preliminary evidence of ubiquitin proteasome system dysregulation in schizophrenia and bipolar disorder: convergent pathway analysis findings from two independent samples","volume":"153b","author":"Bousman","year":"2010","journal-title":"Am. J. Med. Genet. B Neuropsychiatr. Genet."},{"key":"10.1016\/j.pnpbp.2025.111302_bb0030","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1023\/A:1010933404324","article-title":"Random forests","volume":"45","author":"Breiman","year":"2001","journal-title":"Mach. Learn."},{"key":"10.1016\/j.pnpbp.2025.111302_bb0035","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.celrep.2016.12.019","article-title":"Pan-cancer Immunogenomic analyses reveal genotype-Immunophenotype relationships and predictors of response to checkpoint blockade","volume":"18","author":"Charoentong","year":"2017","journal-title":"Cell Rep."},{"key":"10.1016\/j.pnpbp.2025.111302_bb0040","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1186\/1471-2105-8-74","article-title":"Gene selection with multiple ordering criteria","volume":"8","author":"Chen","year":"2007","journal-title":"BMC Bioinform."},{"key":"10.1016\/j.pnpbp.2025.111302_bb0045","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1038\/s41380-022-01854-7","article-title":"Neuroimmune transcriptome changes in patient brains of psychiatric and neurological disorders","volume":"28","author":"Chen","year":"2023","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.pnpbp.2025.111302_bb0050","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/1471-2105-7-3","article-title":"Gene selection and classification of microarray data using random forest","volume":"7","author":"Diaz-Uriarte","year":"2006","journal-title":"BMC Bioinform."},{"key":"10.1016\/j.pnpbp.2025.111302_bb0055","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1038\/npp.2013.255","article-title":"DeltaFosB induction in prefrontal cortex by antipsychotic drugs is associated with negative behavioral outcomes","volume":"39","author":"Dietz","year":"2014","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.pnpbp.2025.111302_bb0060","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1146\/annurev-clinpsy-032816-045037","article-title":"Machine learning approaches for clinical psychology and psychiatry","volume":"14","author":"Dwyer","year":"2018","journal-title":"Annu. Rev. Clin. Psychol."},{"key":"10.1016\/j.pnpbp.2025.111302_bb0065","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0155631","article-title":"Peripheral immune cell populations associated with cognitive deficits and negative symptoms of treatment-resistant schizophrenia","volume":"11","author":"Fernandez-Egea","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.pnpbp.2025.111302_bb0070","doi-asserted-by":"crossref","first-page":"1","DOI":"10.18637\/jss.v033.i01","article-title":"Regularization paths for generalized linear models via coordinate descent","volume":"33","author":"Friedman","year":"2010","journal-title":"J. Stat. Softw."},{"key":"10.1016\/j.pnpbp.2025.111302_bb0075","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1097\/YCO.0000000000000498","article-title":"MRI investigation of immune dysregulation in schizophrenia","volume":"32","author":"Gangadin","year":"2019","journal-title":"Curr. Opin. Psychiatry"},{"key":"10.1016\/j.pnpbp.2025.111302_bb0080","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1186\/s12888-023-04760-6","article-title":"The association between schizophrenia and white blood cells count: a bidirectional two-sample Mendelian randomization study","volume":"23","author":"Gao","year":"2023","journal-title":"BMC Psychiatry"},{"key":"10.1016\/j.pnpbp.2025.111302_bb0085","doi-asserted-by":"crossref","DOI":"10.2202\/1544-6115.1536","article-title":"Lasso logistic regression, GSoft and the cyclic coordinate descent algorithm: application to gene expression data","volume":"9","author":"Garcia-Magarinos","year":"2010","journal-title":"Stat. Appl. Genet. Mol. Biol."},{"key":"10.1016\/j.pnpbp.2025.111302_bb0090","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.1038\/mp.2016.3","article-title":"A meta-analysis of blood cytokine network alterations in psychiatric patients: comparisons between schizophrenia, bipolar disorder and depression","volume":"21","author":"Goldsmith","year":"2016","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.pnpbp.2025.111302_bb0095","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.schres.2016.07.006","article-title":"Transcriptome-wide mega-analyses reveal joint dysregulation of immunologic genes and transcription regulators in brain and blood in schizophrenia","volume":"176","author":"Hess","year":"2016","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.pnpbp.2025.111302_bb0100","doi-asserted-by":"crossref","first-page":"232","DOI":"10.3389\/fgene.2019.00232","article-title":"Central and peripheral changes in FOS expression in schizophrenia based on genome-wide gene expression","volume":"10","author":"Huang","year":"2019","journal-title":"Front. Genet."},{"key":"10.1016\/j.pnpbp.2025.111302_bb0105","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1111\/acps.13140","article-title":"Meta-analysis of total and differential white blood cell counts in schizophrenia","volume":"142","author":"Jackson","year":"2020","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/j.pnpbp.2025.111302_bb0110","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/S0955-0674(97)80068-3","article-title":"AP-1 function and regulation","volume":"9","author":"Karin","year":"1997","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.pnpbp.2025.111302_bb0115","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/S2215-0366(14)00122-9","article-title":"Inflammation and immunity in schizophrenia: implications for pathophysiology and treatment","volume":"2","author":"Khandaker","year":"2015","journal-title":"Lancet Psychiatry"},{"key":"10.1016\/j.pnpbp.2025.111302_bb0120","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1038\/s41587-019-0201-4","article-title":"Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype","volume":"37","author":"Kim","year":"2019","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.pnpbp.2025.111302_bb0125","doi-asserted-by":"crossref","first-page":"43","DOI":"10.2478\/enr-2020-0006","article-title":"C-Fos and FosB\/DeltaFosB colocalizations in selected forebrain structures after olanzapine, amisulpride, aripiprazole, and quetiapine single administration in rats preconditioned by two different mild stressors sequences","volume":"54","author":"Kiss","year":"2020","journal-title":"Endocr. Regul."},{"key":"10.1016\/j.pnpbp.2025.111302_bb0130","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1186\/1471-2105-9-559","article-title":"WGCNA: an R package for weighted correlation network analysis","volume":"9","author":"Langfelder","year":"2008","journal-title":"BMC Bioinform."},{"key":"10.1016\/j.pnpbp.2025.111302_bb0135","doi-asserted-by":"crossref","first-page":"2078","DOI":"10.1093\/bioinformatics\/btp352","article-title":"The sequence alignment\/map format and SAMtools","volume":"25","author":"Li","year":"2009","journal-title":"Bioinformatics"},{"key":"10.1016\/j.pnpbp.2025.111302_bb0140","doi-asserted-by":"crossref","first-page":"9929","DOI":"10.2147\/OTT.S259336","article-title":"Long non-coding RNA NCK1-AS1 serves an oncogenic role in gastric cancer by regulating miR-137\/NUP43 Axis","volume":"13","author":"Li","year":"2020","journal-title":"Onco Targets Ther"},{"key":"10.1016\/j.pnpbp.2025.111302_bb0145","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1093\/bioinformatics\/btt656","article-title":"featureCounts: an efficient general purpose program for assigning sequence reads to genomic features","volume":"30","author":"Liao","year":"2014","journal-title":"Bioinformatics"},{"key":"10.1016\/j.pnpbp.2025.111302_bb0150","first-page":"8468","article-title":"MiRNA-409-5p dysregulation promotes imatinib resistance and disease progression in children with chronic myeloid leukemia","volume":"23","author":"Liu","year":"2019","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"key":"10.1016\/j.pnpbp.2025.111302_bb0155","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1186\/s13059-014-0550-8","article-title":"Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2","volume":"15","author":"Love","year":"2014","journal-title":"Genome Biol."},{"key":"10.1016\/j.pnpbp.2025.111302_bb0160","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.brainresbull.2016.08.008","article-title":"Impact of repeated asenapine treatment on FosB\/DeltaFosB expression in the forebrain structures under normal conditions and mild stress preconditioning in the rat","volume":"127","author":"Majercikova","year":"2016","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.pnpbp.2025.111302_bb0165","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1001\/jamapsychiatry.2019.3360","article-title":"Schizophrenia-an overview","volume":"77","author":"McCutcheon","year":"2020","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.pnpbp.2025.111302_bb0170","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1093\/schbul\/sby024","article-title":"Inflammation in schizophrenia: Pathogenetic aspects and therapeutic considerations","volume":"44","author":"Muller","year":"2018","journal-title":"Schizophr. Bull."},{"key":"10.1016\/j.pnpbp.2025.111302_bb0175","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1038\/nmeth.3337","article-title":"Robust enumeration of cell subsets from tissue expression profiles","volume":"12","author":"Newman","year":"2015","journal-title":"Nat. Methods"},{"key":"10.1016\/j.pnpbp.2025.111302_bb0180","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/0920-9964(94)00039-B","article-title":"Abnormal distributions of T-lymphocyte subsets in the cerebrospinal fluid of patients with acute schizophrenia","volume":"14","author":"Nikkila","year":"1995","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.pnpbp.2025.111302_bb0185","doi-asserted-by":"crossref","first-page":"83","DOI":"10.2478\/enr-2019-0010","article-title":"Clozapine impact on FosB\/DeltaFosB expression in stress preconditioned rats: response to a novel stressor","volume":"53","author":"Osacka","year":"2019","journal-title":"Endocr. Regul."},{"key":"10.1016\/j.pnpbp.2025.111302_bb0190","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1093\/schbul\/12.1.83","article-title":"Biological studies of schizophrenia in Europe","volume":"12","author":"Prilipko","year":"1986","journal-title":"Schizophr. Bull."},{"key":"10.1016\/j.pnpbp.2025.111302_bb0195","doi-asserted-by":"crossref","first-page":"97","DOI":"10.17116\/jnevro202012004197","article-title":"The functional activity of neutrophils in paranoid schizophrenia and Alzheimer\u2019s disease","volume":"120","author":"Proskurnina","year":"2020","journal-title":"Zh. Nevrol. Psikhiatr. Im. S S Korsakova"},{"key":"10.1016\/j.pnpbp.2025.111302_bb0200","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1006\/exnr.2000.7612","article-title":"Enhancement of laminar FosB expression in frontal cortex of rats receiving long chronic clozapine administration","volume":"168","author":"Rodriguez","year":"2001","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.pnpbp.2025.111302_bb0205","doi-asserted-by":"crossref","first-page":"2000","DOI":"10.3390\/genes12122000","article-title":"Spatial and temporal expression of high-mobility-group nucleosome-binding (HMGN) genes in brain areas associated with cognition in individuals with down syndrome","volume":"12","author":"Rodriguez-Ortiz","year":"2021","journal-title":"Genes (Basel)"},{"key":"10.1016\/j.pnpbp.2025.111302_bb0210","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.schres.2017.10.023","article-title":"Improving individual predictions: machine learning approaches for detecting and attacking heterogeneity in schizophrenia (and other psychiatric diseases)","volume":"214","author":"Schnack","year":"2019","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.pnpbp.2025.111302_bb0215","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/S0920-9964(98)00175-3","article-title":"T-cell subsets in schizophrenia: a comparison between drug-naive first episode patients and chronic schizophrenic patients","volume":"38","author":"Sperner-Unterweger","year":"1999","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.pnpbp.2025.111302_bb0220","doi-asserted-by":"crossref","DOI":"10.1016\/j.artmed.2019.101704","article-title":"Machine learning and big data: implications for disease modeling and therapeutic discovery in psychiatry","volume":"99","author":"Tai","year":"2019","journal-title":"Artif. Intell. Med."},{"key":"10.1016\/j.pnpbp.2025.111302_bb0225","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.2217\/fon-2017-0690","article-title":"High NUP43 expression might independently predict poor overall survival in luminal a and in HER2+ breast cancer","volume":"14","author":"Tian","year":"2018","journal-title":"Future Oncol."},{"key":"10.1016\/j.pnpbp.2025.111302_bb0230","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1016\/j.cell.2006.05.027","article-title":"Dynamic nuclear pore complexes: life on the edge","volume":"125","author":"Tran","year":"2006","journal-title":"Cell"},{"key":"10.1016\/j.pnpbp.2025.111302_bb0235","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1038\/mp.2016.90","article-title":"Postmortem evidence of cerebral inflammation in schizophrenia: a systematic review","volume":"21","author":"Trepanier","year":"2016","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.pnpbp.2025.111302_bb0240","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1161\/CIRCRESAHA.118.313944","article-title":"Translational medicine in the era of big data and machine learning","volume":"123","author":"Weintraub","year":"2018","journal-title":"Circ. Res."},{"key":"10.1016\/j.pnpbp.2025.111302_bb0245","doi-asserted-by":"crossref","first-page":"3226","DOI":"10.1007\/s12035-024-04461-5","article-title":"Identification of immune-related biomarkers of schizophrenia in the central nervous system using Bioinformatic methods and machine learning algorithms","volume":"62","author":"Weng","year":"2025","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.pnpbp.2025.111302_bb0250","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.jpsychires.2022.06.007","article-title":"Identifying crucial biomarkers in peripheral blood of schizophrenia and screening therapeutic agents by comprehensive bioinformatics analysis","volume":"152","author":"Xie","year":"2022","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.pnpbp.2025.111302_bb0255","doi-asserted-by":"crossref","first-page":"3247","DOI":"10.1016\/j.febslet.2015.09.008","article-title":"Crystal structure of human nuclear pore complex component NUP43","volume":"589","author":"Xu","year":"2015","journal-title":"FEBS Lett."},{"key":"10.1016\/j.pnpbp.2025.111302_bb0260","doi-asserted-by":"crossref","DOI":"10.2202\/1544-6115.1128","article-title":"A general framework for weighted gene co-expression network analysis","volume":"4","author":"Zhang","year":"2005","journal-title":"Stat. Appl. Genet. Mol. Biol."},{"key":"10.1016\/j.pnpbp.2025.111302_bb0265","doi-asserted-by":"crossref","DOI":"10.3389\/fncel.2023.1256184","article-title":"Identification of immune-related biomarkers in peripheral blood of schizophrenia using bioinformatic methods and machine learning algorithms","volume":"17","author":"Zhu","year":"2023","journal-title":"Front. Cell. Neurosci."}],"container-title":["Progress in Neuro-Psychopharmacology and Biological Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278584625000569?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278584625000569?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T19:28:07Z","timestamp":1762284487000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0278584625000569"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":53,"alternative-id":["S0278584625000569"],"URL":"https:\/\/doi.org\/10.1016\/j.pnpbp.2025.111302","relation":{},"ISSN":["0278-5846"],"issn-type":[{"value":"0278-5846","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Identifying periphery biomarkers of first-episode drug-na\u00efve patients with schizophrenia using machine-learning-based strategies","name":"articletitle","label":"Article Title"},{"value":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pnpbp.2025.111302","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"111302"}}