{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T20:53:12Z","timestamp":1778705592570,"version":"3.51.4"},"reference-count":185,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T00:00:00Z","timestamp":1753401600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003407","name":"Ministero dell\u2019Istruzione, dell\u2019Universit\u00e0 e della Ricerca","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003407","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Progress in Neuro-Psychopharmacology and Biological Psychiatry"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1016\/j.pnpbp.2025.111458","type":"journal-article","created":{"date-parts":[[2025,7,20]],"date-time":"2025-07-20T14:24:00Z","timestamp":1753021440000},"page":"111458","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Updates on first- and second-generation antidepressants used in the treatment of traumatic brain injury-induced depression"],"prefix":"10.1016","volume":"141","author":[{"given":"Nicla","family":"Tranchida","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca","family":"Inferrera","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salvatore","family":"Cuzzocrea","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marika","family":"Cordaro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosanna","family":"Di Paola","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.pnpbp.2025.111458_bb0005","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1080\/01616412.2015.1110402","article-title":"Traumatic brain injury decreases serotonin transporter expression in the rat cerebrum","volume":"38","author":"Abe","year":"2016","journal-title":"Neurol. Res."},{"issue":"1","key":"10.1016\/j.pnpbp.2025.111458_bb0010","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1007\/s12028-020-00994-4","article-title":"Contusion progression following traumatic brain injury: a review of clinical and radiological predictors, and influence on outcome","volume":"34","author":"Adatia","year":"2021","journal-title":"Neurocrit. Care."},{"issue":"1","key":"10.1016\/j.pnpbp.2025.111458_bb0015","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.imr.2019.01.001","article-title":"Should RCT's be used as the gold standard for evidence based medicine?","volume":"8","author":"Ahuja","year":"2019","journal-title":"Integr Med Res"},{"key":"10.1016\/j.pnpbp.2025.111458_bb0020","doi-asserted-by":"crossref","unstructured":"Alam, A., Z. Voronovich, and J.A. Carley, A review of therapeutic uses of mirtazapine in psychiatric and medical conditions. Prim Care Companion CNS Disord, 2013. 15(5).","DOI":"10.4088\/PCC.13r01525"},{"issue":"16","key":"10.1016\/j.pnpbp.2025.111458_bb0025","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1089\/neu.2014.3651","article-title":"Patterns of depression treatment in Medicare beneficiaries with depression after traumatic brain injury","volume":"32","author":"Albrecht","year":"2015","journal-title":"J. Neurotrauma"},{"issue":"6","key":"10.1016\/j.pnpbp.2025.111458_bb0030","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1017\/S0033291715002986","article-title":"A prospective examination of Axis I psychiatric disorders in the first 5 years following moderate to severe traumatic brain injury","volume":"46","author":"Alway","year":"2016","journal-title":"Psychol. Med."},{"issue":"4","key":"10.1016\/j.pnpbp.2025.111458_bb0035","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/j.freeradbiomed.2008.04.038","article-title":"Oxidative stress and modification of synaptic proteins in hippocampus after traumatic brain injury","volume":"45","author":"Ansari","year":"2008","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.pnpbp.2025.111458_bb0040","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.bbr.2018.04.009","article-title":"Evaluation of early chronic functional outcomes and their relationship to pre-frontal cortex and hippocampal pathology following moderate-severe traumatic brain injury","volume":"348","author":"Arulsamy","year":"2018","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.pnpbp.2025.111458_bb0045","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.apmr.2003.08.117","article-title":"Psychiatric challenges in the first 6 years after traumatic brain injury: cross-sequential analyses of Axis I disorders","volume":"85","author":"Ashman","year":"2004","journal-title":"Arch. Phys. Med. Rehabil."},{"issue":"5","key":"10.1016\/j.pnpbp.2025.111458_bb0050","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1016\/j.apmr.2008.11.005","article-title":"A randomized controlled trial of sertraline for the treatment of depression in persons with traumatic brain injury","volume":"90","author":"Ashman","year":"2009","journal-title":"Arch. Phys. Med. Rehabil."},{"issue":"6","key":"10.1016\/j.pnpbp.2025.111458_bb0055","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1097\/HTR.0000000000000098","article-title":"Comparison of cognitive behavioral therapy and supportive psychotherapy for the treatment of depression following traumatic brain injury: a randomized controlled trial","volume":"29","author":"Ashman","year":"2014","journal-title":"J. Head Trauma Rehabil."},{"issue":"2","key":"10.1016\/j.pnpbp.2025.111458_bb0060","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1227\/00006123-198602000-00023","article-title":"Pathophysiology of cerebrospinal fluid in head injury: part 1 pathological changes in cerebrospinal fluid solute composition after traumatic injury","volume":"18","author":"Bakay","year":"1986","journal-title":"Neurosurgery"},{"issue":"5","key":"10.1016\/j.pnpbp.2025.111458_bb0065","first-page":"206","article-title":"Insights into the mechanisms of action of the MAO inhibitors phenelzine and tranylcypromine: a review","volume":"17","author":"Baker","year":"1992","journal-title":"J. Psychiatry Neurosci."},{"issue":"10","key":"10.1016\/j.pnpbp.2025.111458_bb0070","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.3109\/02699052.2013.801513","article-title":"Treatment for depression following mild traumatic brain injury in adults: a meta-analysis","volume":"27","author":"Barker-Collo","year":"2013","journal-title":"Brain Inj."},{"issue":"10","key":"10.1016\/j.pnpbp.2025.111458_bb0075","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1080\/02699052.2020.1797169","article-title":"The management of depression following traumatic brain injury: A systematic review with meta-analysis","volume":"34","author":"Beedham","year":"2020","journal-title":"Brain Inj."},{"issue":"2","key":"10.1016\/j.pnpbp.2025.111458_bb0080","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.neuroimage.2008.04.254","article-title":"Longitudinal changes in patients with traumatic brain injury assessed with diffusion-tensor and volumetric imaging","volume":"42","author":"Bendlin","year":"2008","journal-title":"Neuroimage"},{"issue":"5","key":"10.1016\/j.pnpbp.2025.111458_bb0085","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1016\/j.mcna.2014.06.013","article-title":"Major Depression","volume":"98","author":"Bentley","year":"2014","journal-title":"Med. Clin. North Am."},{"issue":"7-8","key":"10.1016\/j.pnpbp.2025.111458_bb0090","doi-asserted-by":"crossref","first-page":"664","DOI":"10.3109\/02699052.2011.576306","article-title":"Effectiveness of physical therapy for improving gait and balance in individuals with traumatic brain injury: a systematic review","volume":"25","author":"Bland","year":"2011","journal-title":"Brain Inj."},{"issue":"10","key":"10.1016\/j.pnpbp.2025.111458_bb0095","doi-asserted-by":"crossref","first-page":"1693","DOI":"10.4103\/1673-5374.238604","article-title":"Depression following a traumatic brain injury: uncovering cytokine dysregulation as a pathogenic mechanism","volume":"13","author":"Bodnar","year":"2018","journal-title":"Neural Regen. Res."},{"issue":"11","key":"10.1016\/j.pnpbp.2025.111458_bb0100","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.1089\/neu.2018.6127","article-title":"A systematic review of closed head injury models of mild traumatic brain injury in mice and rats","volume":"36","author":"Bodnar","year":"2019","journal-title":"J. Neurotrauma"},{"issue":"1","key":"10.1016\/j.pnpbp.2025.111458_bb0105","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/0014-2999(75)90238-1","article-title":"The monoamine oxidase B inhibitor deprenyl potentiates phenylethylamine behaviour in rats without inhibition of catecholamine metabolite formation","volume":"34","author":"Braestrup","year":"1975","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.pnpbp.2025.111458_bb0110","doi-asserted-by":"crossref","first-page":"26","DOI":"10.3389\/fnagi.2013.00026","article-title":"Brain injury, neuroinflammation and Alzheimer's disease","volume":"5","author":"Breunig","year":"2013","journal-title":"Front. Aging Neurosci."},{"key":"10.1016\/j.pnpbp.2025.111458_bb0115","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1046\/j.1528-1157.44.s10.3.x","article-title":"The epidemiology of traumatic brain injury: a review","volume":"44","author":"Bruns","year":"2003","journal-title":"Epilepsia"},{"issue":"1","key":"10.1016\/j.pnpbp.2025.111458_bb0120","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1001\/archgenpsychiatry.2007.8","article-title":"Neural substrates of symptoms of depression following concussion in male athletes with persisting postconcussion symptoms","volume":"65","author":"Chen","year":"2008","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.pnpbp.2025.111458_bb0125","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1007\/s12975-011-0125-x","article-title":"Blood\u2013brain barrier pathophysiology in traumatic brain injury","volume":"2","author":"Chodobski","year":"2011","journal-title":"Transl. Stroke Res."},{"issue":"7","key":"10.1016\/j.pnpbp.2025.111458_bb0130","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0219137","article-title":"Selective serotonin reuptake inhibitors and risk of epilepsy after traumatic brain injury\u2013A population based cohort study","volume":"14","author":"Christensen","year":"2019","journal-title":"PLoS One"},{"issue":"10128","key":"10.1016\/j.pnpbp.2025.111458_bb0135","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1016\/S0140-6736(17)32802-7","article-title":"Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis","volume":"391","author":"Cipriani","year":"2018","journal-title":"Lancet"},{"issue":"1","key":"10.1016\/j.pnpbp.2025.111458_bb0140","first-page":"89","article-title":"The Glasgow Coma Scale: a European and global perspective on enhancing practice","volume":"33","author":"Cook","year":"2021","journal-title":"Critical Care Nursing Clinics"},{"issue":"8","key":"10.1016\/j.pnpbp.2025.111458_bb0145","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1089\/ars.2012.4981","article-title":"Traumatic brain injury: oxidative stress and neuroprotection","volume":"19","author":"Cornelius","year":"2013","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.pnpbp.2025.111458_bb0150","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1742-2094-9-236","article-title":"New perspectives on central and peripheral immune responses to acute traumatic brain injury","volume":"9","author":"Das","year":"2012","journal-title":"J. Neuroinflammation"},{"issue":"6","key":"10.1016\/j.pnpbp.2025.111458_bb0155","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/j.encep.2016.05.006","article-title":"Antidepressant and tolerance: Determinants and management of major side effects","volume":"42","author":"David","year":"2016","journal-title":"Encephale"},{"issue":"5","key":"10.1016\/j.pnpbp.2025.111458_bb0160","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1177\/0271678X241234770","article-title":"Non-pharmacological interventions for traumatic brain injury","volume":"44","author":"Davis","year":"2024","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.pnpbp.2025.111458_bb0165","series-title":"Traumatic Brain Injury (TBI)","author":"Dawodu","year":"2012"},{"issue":"3","key":"10.1016\/j.pnpbp.2025.111458_bb0170","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.neuchi.2020.11.010","article-title":"Diagnosis clinical criteria of sport related concussion: Toward an operational criteria definition in France","volume":"67","author":"Decq","year":"2021","journal-title":"Neurochirurgie"},{"issue":"7","key":"10.1016\/j.pnpbp.2025.111458_bb0175","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1002\/pmrj.12657","article-title":"Prevalence of depression and anxiety disorders following mild traumatic brain injury","volume":"14","author":"Delmonico","year":"2022","journal-title":"PM&R"},{"issue":"7","key":"10.1016\/j.pnpbp.2025.111458_bb0180","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1177\/0963689717714098","article-title":"Inflammation relates to chronic behavioral and neurological symptoms in military personnel with traumatic brain injuries","volume":"26","author":"Devoto","year":"2017","journal-title":"Cell Transplant."},{"issue":"4","key":"10.1016\/j.pnpbp.2025.111458_bb0185","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.3171\/2017.10.JNS17352","article-title":"Estimating the global incidence of traumatic brain injury","volume":"130","author":"Dewan","year":"2018","journal-title":"J. Neurosurg."},{"issue":"6","key":"10.1016\/j.pnpbp.2025.111458_bb0190","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1089\/neu.2007.0439","article-title":"Blast-Induced Brain Injury and Posttraumatic Hypotension and Hypoxemia","volume":"26","author":"DeWitt","year":"2008","journal-title":"J. Neurotrauma"},{"issue":"4","key":"10.1016\/j.pnpbp.2025.111458_bb0195","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1111\/j.1600-0447.1992.tb01472.x","article-title":"Treatment resistance of depression after head injury: a preliminary study of amitriptyline response","volume":"85","author":"Dinan","year":"1992","journal-title":"Acta Psychiatr. Scand."},{"issue":"51","key":"10.1016\/j.pnpbp.2025.111458_bb0200","first-page":"25","article-title":"especially with other psychotropics","volume":"10","author":"Drug interactions with selective serotonin reuptake inhibitors","year":"2001","journal-title":"Prescrire Int"},{"issue":"3","key":"10.1016\/j.pnpbp.2025.111458_bb0205","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1001\/archpsyc.64.3.327","article-title":"The role of dopamine in the pathophysiology of depression","volume":"64","author":"Dunlop","year":"2007","journal-title":"Arch. Gen. Psychiatry"},{"issue":"3","key":"10.1016\/j.pnpbp.2025.111458_bb0210","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1097\/HTR.0000000000000177","article-title":"Evaluating the psychometric properties of 3 depression measures in a sample of persons with traumatic brain injury and major depressive disorder","volume":"31","author":"Dyer","year":"2016","journal-title":"J. Head Trauma Rehabil."},{"issue":"38","key":"10.1016\/j.pnpbp.2025.111458_bb0215","doi-asserted-by":"crossref","first-page":"9962","DOI":"10.1523\/JNEUROSCI.1898-15.2016","article-title":"Interfering with the chronic immune response rescues chronic degeneration after traumatic brain injury","volume":"36","author":"Ert\u00fcrk","year":"2016","journal-title":"J. Neurosci."},{"issue":"9","key":"10.1016\/j.pnpbp.2025.111458_bb0220","doi-asserted-by":"crossref","first-page":"e2019686","DOI":"10.1001\/jamanetworkopen.2020.19686","article-title":"Prevalence of depression symptoms in US adults before and during the COVID-19 pandemic","volume":"3","author":"Ettman","year":"2020","journal-title":"JAMA Netw. Open"},{"issue":"3","key":"10.1016\/j.pnpbp.2025.111458_bb0225","first-page":"289","volume":"32","author":"Fakhoury","year":"2021","journal-title":"Depression following traumatic brain injury: a comprehensive overview."},{"issue":"1","key":"10.1016\/j.pnpbp.2025.111458_bb0230","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1001\/archpsyc.61.1.53","article-title":"Psychiatric illness following traumatic brain injury in an adult healthMaintenance organization population","volume":"61","author":"Fann","year":"2004","journal-title":"Arch. Gen. Psychiatry"},{"issue":"12","key":"10.1016\/j.pnpbp.2025.111458_bb0235","doi-asserted-by":"crossref","first-page":"2383","DOI":"10.1089\/neu.2009.1091","article-title":"Treatment for depression after traumatic brain injury: a systematic review","volume":"26","author":"Fann","year":"2009","journal-title":"J. Neurotrauma"},{"issue":"5","key":"10.1016\/j.pnpbp.2025.111458_bb0240","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1097\/HTR.0000000000000322","article-title":"Sertraline for major depression during the year following traumatic brain injury: a randomized controlled trial","volume":"32","author":"Fann","year":"2017","journal-title":"J. Head Trauma Rehabil."},{"issue":"5","key":"10.1016\/j.pnpbp.2025.111458_bb0245","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1016\/j.biopsych.2021.07.008","article-title":"Treatment of psychiatric problems after traumatic brain injury","volume":"91","author":"Fann","year":"2022","journal-title":"Biol. Psychiatry"},{"issue":"20","key":"10.1016\/j.pnpbp.2025.111458_bb0250","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1093\/eurheartj\/ehu100","article-title":"Risk of arrhythmia induced by psychotropic medications: a proposal for clinical management","volume":"35","author":"Fanoe","year":"2014","journal-title":"Eur. Heart J."},{"issue":"3","key":"10.1016\/j.pnpbp.2025.111458_bb0255","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/S0304-3940(00)00977-0","article-title":"Temporal profile of release of interleukin-1\u03b2 in neurotrauma","volume":"284","author":"Fassbender","year":"2000","journal-title":"Neurosci. Lett."},{"issue":"4","key":"10.1016\/j.pnpbp.2025.111458_bb0260","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1097\/00131746-200407000-00005","article-title":"The role of monoamine oxidase inhibitors in current psychiatric practice","volume":"10","author":"Fiedorowicz","year":"2004","journal-title":"J. Psychiatr. Pract."},{"key":"10.1016\/j.pnpbp.2025.111458_bb0265","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1007\/s10787-012-0164-2","article-title":"Neuroinflammation: beneficial and detrimental effects after traumatic brain injury","volume":"21","author":"Finnie","year":"2013","journal-title":"Inflammopharmacology"},{"issue":"1","key":"10.1016\/j.pnpbp.2025.111458_bb0270","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1007\/s12028-022-01609-w","article-title":"Time course and clinical significance of hematoma expansion in moderate-to-severe traumatic brain injury: an observational cohort study","volume":"38","author":"Fletcher-Sandersj\u00f6\u00f6","year":"2023","journal-title":"Neurocrit. Care."},{"issue":"2","key":"10.1016\/j.pnpbp.2025.111458_bb0275","doi-asserted-by":"crossref","first-page":"43","DOI":"10.3390\/pharmacy6020043","article-title":"Comprehension of top 200 prescribed drugs in the US as a resource for pharmacy teaching, training and practice","volume":"6","author":"Fuentes","year":"2018","journal-title":"Pharmacy"},{"issue":"7","key":"10.1016\/j.pnpbp.2025.111458_bb0280","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1089\/neu.2017.5371","article-title":"Geriatric Traumatic Brain Injury: Epidemiology, Outcomes, Knowledge Gaps, and Future Directions","volume":"35","author":"Gardner","year":"2018","journal-title":"J. Neurotrauma"},{"issue":"11","key":"10.1016\/j.pnpbp.2025.111458_bb0285","doi-asserted-by":"crossref","first-page":"772","DOI":"10.7326\/0003-4819-155-11-201112060-00009","article-title":"Comparative benefits and harms of second-generation antidepressants for treating major depressive disorder: an updated meta-analysis","volume":"155","author":"Gartlehner","year":"2011","journal-title":"Ann. Intern. Med."},{"issue":"7","key":"10.1016\/j.pnpbp.2025.111458_bb0290","doi-asserted-by":"crossref","first-page":"4141","DOI":"10.1007\/s12035-022-02822-6","article-title":"A literature review of traumatic brain injury biomarkers","volume":"59","author":"Ghaith","year":"2022","journal-title":"Mol. Neurobiol."},{"issue":"1","key":"10.1016\/j.pnpbp.2025.111458_bb0295","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.psychres.2014.01.046","article-title":"Lower health related quality of life in US military personnel is associated with service-related disorders and inflammation","volume":"216","author":"Gill","year":"2014","journal-title":"Psychiatry Res."},{"issue":"6","key":"10.1016\/j.pnpbp.2025.111458_bb0300","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1038\/sj.bjp.0707253","article-title":"Tricyclic antidepressant pharmacology and therapeutic drug interactions updated","volume":"151","author":"Gillman","year":"2007","journal-title":"Br. J. Pharmacol."},{"issue":"13","key":"10.1016\/j.pnpbp.2025.111458_bb0305","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1089\/neu.2013.3080","article-title":"Delayed increases in microvascular pathology after experimental traumatic brain injury are associated with prolonged inflammation, blood\u2013brain barrier disruption, and progressive white matter damage","volume":"31","author":"Glushakova","year":"2014","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.pnpbp.2025.111458_bb0310","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21249532","article-title":"Dremencov Mechanism of Action of Atypical Antipsychotic Drugs in Mood Disorders","volume":"21","author":"Grinchii","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"4","key":"10.1016\/j.pnpbp.2025.111458_bb0315","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1136\/emj.2009.076596","article-title":"Analysis of amitriptyline overdose in emergency medicine","volume":"28","author":"G\u00fcloglu","year":"2011","journal-title":"Emerg. Med. J."},{"issue":"4","key":"10.1016\/j.pnpbp.2025.111458_bb0320","doi-asserted-by":"crossref","first-page":"535","DOI":"10.23736\/S1973-9087.21.06491-1","article-title":"Comorbidity in traumatic brain injury and functional outcomes: a systematic review","volume":"57","author":"Hanafy","year":"2021","journal-title":"Eur J Phys Rehabil Med"},{"issue":"10","key":"10.1016\/j.pnpbp.2025.111458_bb0325","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1089\/neu.2008.0735","article-title":"Traumatic brain injury and long-term quality of life: findings from an Australian study","volume":"26","author":"Hawthorne","year":"2009","journal-title":"J. Neurotrauma"},{"issue":"12","key":"10.1016\/j.pnpbp.2025.111458_bb0330","first-page":"1147","article-title":"Blood-brain barrier disruption is an early event that may persist for many years after traumatic brain injury in humans","volume":"74","author":"Hay","year":"2015","journal-title":"J. Neuropathol. Exp. Neurol."},{"issue":"4","key":"10.1016\/j.pnpbp.2025.111458_bb0335","doi-asserted-by":"crossref","DOI":"10.3390\/ijms20040822","article-title":"Strategies to Treat Chronic Pain and Strengthen Impaired Descending Noradrenergic Inhibitory System","volume":"20","author":"Hayashida","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.pnpbp.2025.111458_bb0340","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.brainres.2015.12.024","article-title":"Therapies negating neuroinflammation after brain trauma","volume":"1640","author":"Hellewell","year":"2016","journal-title":"Brain Res."},{"key":"10.1016\/j.pnpbp.2025.111458_bb0345","first-page":"25","article-title":"Chronic SSRI stimulation of astrocytic 5-HT2B receptors change multiple gene expressions\/editings and metabolism of glutamate, glucose and glycogen: a potential paradigm shift","volume":"9","author":"Hertz","year":"2015","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.pnpbp.2025.111458_bb0350","article-title":"New generation antidepressants for depression in children and adolescents: a network meta-analysis","volume":"5","author":"Hetrick","year":"2021","journal-title":"Cochrane Database Syst. Rev."},{"issue":"2","key":"10.1016\/j.pnpbp.2025.111458_bb0355","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1007\/s11065-022-09543-6","article-title":"Effectiveness of Pharmacotherapy for Depression after Adult Traumatic Brain Injury: an Umbrella Review","volume":"33","author":"Hicks","year":"2023","journal-title":"Neuropsychol. Rev."},{"issue":"6","key":"10.1016\/j.pnpbp.2025.111458_bb0360","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1055\/s-0031-1286287","article-title":"AGNP Consensus Guidelines for Therapeutic Drug Monitoring in Psychiatry: Update 2011","volume":"44","author":"Hiemke","year":"2011","journal-title":"Pharmacopsychiatry"},{"issue":"1","key":"10.1016\/j.pnpbp.2025.111458_bb0365","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1037\/a0038550","article-title":"A brief history of the development of antidepressant drugs: from monoamines to glutamate","volume":"23","author":"Hillhouse","year":"2015","journal-title":"Exp. Clin. Psychopharmacol."},{"issue":"5","key":"10.1016\/j.pnpbp.2025.111458_bb0370","doi-asserted-by":"crossref","DOI":"10.1097\/00004714-199010000-00007","article-title":"Apathy and Indifference in Patients on Fluvoxamine: and Fluoxetine","volume":"10","author":"Hoehn-Saric","year":"1990","journal-title":"J. Clin. Psychopharmacol."},{"issue":"3","key":"10.1016\/j.pnpbp.2025.111458_bb0375","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1080\/026990501300005659","article-title":"Traumatic brain injury (TBI) 10? 20 years later: a comprehensive outcome study of psychiatric symptomatology, cognitive abilities and psychosocial functioning","volume":"15","author":"Hoofien","year":"2001","journal-title":"Brain Inj."},{"issue":"3","key":"10.1016\/j.pnpbp.2025.111458_bb0380","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.pscychresns.2010.10.003","article-title":"Brain morphometry changes and depressive symptoms after traumatic brain injury","volume":"191","author":"Hudak","year":"2011","journal-title":"Psychiatry Res. Neuroimaging"},{"issue":"10","key":"10.1016\/j.pnpbp.2025.111458_bb0385","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1089\/neu.2007.0295","article-title":"Inflammation in human brain injury: Intracerebral concentrations of IL-1 \u03b1, IL-1 \u03b2, and their endogenous inhibitor IL-1ra","volume":"24","author":"Hutchinson","year":"2007","journal-title":"J. Neurotrauma"},{"issue":"5","key":"10.1016\/j.pnpbp.2025.111458_bb0390","doi-asserted-by":"crossref","first-page":"519","DOI":"10.2174\/1568007023338987","article-title":"Serotonin transporters","volume":"1","author":"Inoue","year":"2002","journal-title":"Current Drug Targets-CNS & Neurological Disorders"},{"key":"10.1016\/j.pnpbp.2025.111458_bb0395","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.yebeh.2016.01.029","article-title":"Proconvulsant effects of antidepressants - What is the current evidence?","volume":"61","author":"Johannessen Landmark","year":"2016","journal-title":"Epilepsy Behav."},{"issue":"4","key":"10.1016\/j.pnpbp.2025.111458_bb0400","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/0165-0327(93)90047-N","article-title":"Depression following traumatic brain injury: a 1 year longitudinal study","volume":"27","author":"Jorge","year":"1993","journal-title":"J. Affect. Disord."},{"issue":"1","key":"10.1016\/j.pnpbp.2025.111458_bb0405","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1001\/archpsyc.61.1.42","article-title":"Major depression following traumatic brain injury","volume":"61","author":"Jorge","year":"2004","journal-title":"Arch. Gen. Psychiatry"},{"issue":"10","key":"10.1016\/j.pnpbp.2025.111458_bb0410","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1001\/jamapsychiatry.2016.2189","article-title":"Sertraline for preventing mood disorders following traumatic brain injury: a randomized clinical trial","volume":"73","author":"Jorge","year":"2016","journal-title":"JAMA psychiatry"},{"issue":"1","key":"10.1016\/j.pnpbp.2025.111458_bb0415","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/0014-2999(92)90511-2","article-title":"Presynaptic inhibition by clonidine of neurotransmitter amino acid release in various brain regions","volume":"217","author":"Kamisaki","year":"1992","journal-title":"Eur. J. Pharmacol."},{"issue":"4","key":"10.1016\/j.pnpbp.2025.111458_bb0420","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1272\/jnms.70.313","article-title":"Therapeutic Effects of Milnacipran (Serotonin Noradrenalin Reuptake Inhibitor) on Depression Following Mild and Moderate Traumatic Brain Injury","volume":"70","author":"Kanetani","year":"2003","journal-title":"Journal of Nippon Medical School"},{"issue":"8","key":"10.1016\/j.pnpbp.2025.111458_bb0425","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.2174\/1570159X15666170613083606","article-title":"Recent advances in pathophysiology of traumatic brain injury","volume":"16","author":"Kaur","year":"2018","journal-title":"Curr. Neuropharmacol."},{"issue":"2 Suppl 3","key":"10.1016\/j.pnpbp.2025.111458_bb0430","first-page":"E267","article-title":"Methodology for clinical research","volume":"63","author":"Kiani","year":"2022","journal-title":"J Prev Med Hyg"},{"issue":"3","key":"10.1016\/j.pnpbp.2025.111458_bb0435","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/S0306-4522(01)00300-1","article-title":"The selective 5-HT1A receptor agonist repinotan HCl attenuates histopathology and spatial learning deficits following traumatic brain injury in rats","volume":"106","author":"Kline","year":"2001","journal-title":"Neuroscience"},{"issue":"3","key":"10.1016\/j.pnpbp.2025.111458_bb0440","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1136\/eb-2013-101268","article-title":"Review: SSRIs and TCAs equally effective at treating chronic depression and dysthemia; SSRIs are associated with fewer adverse events than TCAs","volume":"16","author":"Kocsis","year":"2013","journal-title":"Evid Based Ment Health"},{"key":"10.1016\/j.pnpbp.2025.111458_bb0445","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.taap.2017.11.012","article-title":"Anxiolytic-and antidepressant-like effects of Silymarin compared to diazepam and fluoxetine in a mouse model of mild traumatic brain injury","volume":"338","author":"Kosari-Nasab","year":"2018","journal-title":"Toxicol. Appl. Pharmacol."},{"issue":"3","key":"10.1016\/j.pnpbp.2025.111458_bb0450","doi-asserted-by":"crossref","first-page":"E47","DOI":"10.1097\/HTR.0000000000000439","article-title":"The effect of antidepressants on depression after traumatic brain injury: a meta-analysis","volume":"34","author":"Kreitzer","year":"2019","journal-title":"J. Head Trauma Rehabil."},{"issue":"8","key":"10.1016\/j.pnpbp.2025.111458_bb0455","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1016\/j.bbi.2012.06.008","article-title":"Neuroinflammation after traumatic brain injury: opportunities for therapeutic intervention","volume":"26","author":"Kumar","year":"2012","journal-title":"Brain Behav. Immun."},{"issue":"8","key":"10.1016\/j.pnpbp.2025.111458_bb0460","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1001\/archpsyc.57.8.787","article-title":"Reduced brain norepinephrine and dopamine release in treatment-refractory depressive illness: evidence in support of the catecholamine hypothesis of mood disorders","volume":"57","author":"Lambert","year":"2000","journal-title":"Arch. Gen. Psychiatry"},{"issue":"7-8","key":"10.1016\/j.pnpbp.2025.111458_bb0465","doi-asserted-by":"crossref","first-page":"959","DOI":"10.3109\/02699051003789229","article-title":"Genetic predictors of response to treatment with citalopram in depression secondary to traumatic brain injury","volume":"24","author":"Lanct\u00f4t","year":"2010","journal-title":"Brain Inj."},{"issue":"11","key":"10.1016\/j.pnpbp.2025.111458_bb0470","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.1111\/j.1460-9568.1993.tb00217.x","article-title":"Noradrenaline decreases transmission of NMDA-and non-NMDA-receptor mediated monosynaptic EPSPs in rat prefrontal neurons in vitro","volume":"5","author":"Law-Tho","year":"1993","journal-title":"Eur. J. Neurosci."},{"issue":"2","key":"10.1016\/j.pnpbp.2025.111458_bb0475","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1002\/hup.668","article-title":"Comparing effects of methylphenidate, sertraline and placebo on neuropsychiatric sequelae in patients with traumatic brain injury","volume":"20","author":"Lee","year":"2005","journal-title":"Hum. Psychopharmacol. Clin. Exp."},{"issue":"3","key":"10.1016\/j.pnpbp.2025.111458_bb0480","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.neuchi.2020.02.002","article-title":"Definition and epidemiology of mild traumatic brain injury","volume":"67","author":"Lefevre-Dognin","year":"2021","journal-title":"Neurochirurgie"},{"issue":"1-3","key":"10.1016\/j.pnpbp.2025.111458_bb0485","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.ejphar.2013.07.022","article-title":"Dopamine D3 receptor as a new pharmacological target for the treatment of depression","volume":"719","author":"Leggio","year":"2013","journal-title":"Eur. J. Pharmacol."},{"issue":"4","key":"10.1016\/j.pnpbp.2025.111458_bb0490","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1176\/jnp.6.4.443","article-title":"The frontal lobes and traumatic brain injury","volume":"6","author":"Levin","year":"1994","journal-title":"The Journal of neuropsychiatry and clinical neurosciences"},{"issue":"5","key":"10.1016\/j.pnpbp.2025.111458_bb0495","doi-asserted-by":"crossref","first-page":"350","DOI":"10.4037\/ajcc2021163","article-title":"Admission Glasgow Coma Scale score as a predictor of outcome in patients without traumatic brain injury","volume":"30","author":"Li","year":"2021","journal-title":"Am. J. Crit. Care"},{"key":"10.1016\/j.pnpbp.2025.111458_bb0500","doi-asserted-by":"crossref","first-page":"8","DOI":"10.3389\/fneur.2018.00008","article-title":"Microglia and CNS interleukin-1: beyond immunological concepts","volume":"9","author":"Liu","year":"2018","journal-title":"Front. Neurol."},{"key":"10.1016\/j.pnpbp.2025.111458_bb0505","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2019.172775","article-title":"Pharmacological and non-pharmacological interventions of depression after traumatic brain injury: a systematic review","volume":"865","author":"Liu","year":"2019","journal-title":"Eur. J. Pharmacol."},{"issue":"12","key":"10.1016\/j.pnpbp.2025.111458_bb0510","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1016\/j.tips.2010.09.005","article-title":"Neuroprotection for traumatic brain injury: translational challenges and emerging therapeutic strategies","volume":"31","author":"Loane","year":"2010","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.pnpbp.2025.111458_bb0515","first-page":"97","article-title":"Neuroinflammatory responses to traumatic brain injury: etiology, clinical consequences, and therapeutic opportunities","author":"Lozano","year":"2015","journal-title":"Neuropsychiatr. Dis. Treat."},{"issue":"11","key":"10.1016\/j.pnpbp.2025.111458_bb0520","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1016\/S1474-4422(22)00309-X","article-title":"Traumatic brain injury: progress and challenges in prevention, clinical care, and research","volume":"21","author":"Maas","year":"2022","journal-title":"The Lancet Neurology"},{"issue":"6","key":"10.1016\/j.pnpbp.2025.111458_bb0525","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1097\/00024382-200115060-00002","article-title":"Differential release of interleukines 6, 8, and 10 in cerebrospinal fluid and plasma after traumatic brain injury","volume":"15","author":"Maier","year":"2001","journal-title":"Shock"},{"key":"10.1016\/j.pnpbp.2025.111458_bb0530","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.bbr.2014.05.047","article-title":"Volumetrics relate to the development of depression after traumatic brain injury","volume":"271","author":"Maller","year":"2014","journal-title":"Behav. Brain Res."},{"issue":"1","key":"10.1016\/j.pnpbp.2025.111458_bb0535","article-title":"Traumatic brain injury, microglia, and Beta amyloid","volume":"2012","author":"Mannix","year":"2012","journal-title":"Int. J. Alzheimers Dis."},{"key":"10.1016\/j.pnpbp.2025.111458_bb0540","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/BF01411725","article-title":"CSF neurotransmitter metabolites in comatose head injury patients during changes in their clinical state","volume":"138","author":"Markianos","year":"1996","journal-title":"Acta Neurochir."},{"issue":"6","key":"10.1016\/j.pnpbp.2025.111458_bb0545","doi-asserted-by":"crossref","first-page":"688","DOI":"10.3109\/02699052.2015.1004755","article-title":"Updated clinical practice guidelines for concussion\/mild traumatic brain injury and persistent symptoms","volume":"29","author":"Marshall","year":"2015","journal-title":"Brain Inj."},{"key":"10.1016\/j.pnpbp.2025.111458_bb0550","series-title":"Diagnostic Approach to Atypical Parkinsonian Syndromes. Continuum (Minneap Minn)","first-page":"1117","volume":"22(4 Movement Disorders)","author":"McFarland","year":"2016"},{"issue":"11","key":"10.1016\/j.pnpbp.2025.111458_bb0555","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1016\/j.apmr.2010.05.017","article-title":"Position statement: definition of traumatic brain injury","volume":"91","author":"Menon","year":"2010","journal-title":"Arch. Phys. Med. Rehabil."},{"issue":"4","key":"10.1016\/j.pnpbp.2025.111458_bb0560","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1002\/da.22084","article-title":"Cytokine targets in the brain: impact on neurotransmitters and neurocircuits","volume":"30","author":"Miller","year":"2013","journal-title":"Depress. Anxiety"},{"issue":"2","key":"10.1016\/j.pnpbp.2025.111458_bb0565","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1111\/j.1471-4159.1989.tb07349.x","article-title":"Noradrenaline metabolism in neocortex and hippocampus following transient forebrain ischemia in rats: relation to development of selective neuronal necrosis","volume":"53","author":"Miyauchi","year":"1989","journal-title":"J. Neurochem."},{"issue":"11","key":"10.1016\/j.pnpbp.2025.111458_bb0570","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1080\/02699052.2016.1186839","article-title":"Depression following traumatic brain injury: A functional connectivity perspective","volume":"30","author":"Moreno-L\u00f3pez","year":"2016","journal-title":"Brain Inj."},{"issue":"1","key":"10.1016\/j.pnpbp.2025.111458_bb0575","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/0006-8993(91)91162-T","article-title":"Noradrenergic potentiation of excitatory transmitter action in cerebrocortical slices: evidence for mediation by an \u03b11 receptor-linked second messenger pathway","volume":"546","author":"Mouradian","year":"1991","journal-title":"Brain Res."},{"issue":"10","key":"10.1016\/j.pnpbp.2025.111458_bb0580","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1080\/026990599121197","article-title":"Paroxetine versus citalopram treatment of pathological crying after brain injury","volume":"13","author":"Muller","year":"1999","journal-title":"Brain Inj."},{"issue":"5","key":"10.1016\/j.pnpbp.2025.111458_bb0585","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1097\/WNF.0000000000000233","article-title":"Determination of Monoamine Oxidase A and B Activity in Long-Term Treated Patients With Parkinson Disease","volume":"40","author":"M\u00fcller","year":"2017","journal-title":"Clin. Neuropharmacol."},{"issue":"3","key":"10.1016\/j.pnpbp.2025.111458_bb0590","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1136\/bmjebm-2018-110891","article-title":"The effect of publication bias magnitude and direction on the certainty in evidence","volume":"23","author":"Murad","year":"2018","journal-title":"BMJ Evid Based Med"},{"issue":"13-14","key":"10.1016\/j.pnpbp.2025.111458_bb0595","doi-asserted-by":"crossref","first-page":"1508","DOI":"10.3109\/02699052.2013.823562","article-title":"Role of fibrinogen in cerebrovascular dysfunction after traumatic brain injury","volume":"27","author":"Muradashvili","year":"2013","journal-title":"Brain Inj."},{"issue":"7","key":"10.1016\/j.pnpbp.2025.111458_bb0600","doi-asserted-by":"crossref","first-page":"77","DOI":"10.3390\/brainsci7070077","article-title":"Localization of fibrinogen in the vasculo-astrocyte interface after cortical contusion injury in mice","volume":"7","author":"Muradashvili","year":"2017","journal-title":"Brain sciences"},{"issue":"4","key":"10.1016\/j.pnpbp.2025.111458_bb0605","doi-asserted-by":"crossref","DOI":"10.1097\/00001199-198712000-00007","article-title":"Tricyclic antidepressant therapy after traumatic brain injury","volume":"2","author":"Mysiw","year":"1987","journal-title":"J. Head Trauma Rehabil."},{"issue":"1","key":"10.1016\/j.pnpbp.2025.111458_bb0610","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1097\/00002060-198802000-00006","article-title":"Amitriptyline for post-traumatic agitation","volume":"67","author":"Mysiw","year":"1988","journal-title":"Am J Phys Med Rehabil"},{"issue":"10","key":"10.1016\/j.pnpbp.2025.111458_bb0615","doi-asserted-by":"crossref","first-page":"531","DOI":"10.2188\/jea.JE20220147","article-title":"Development and validation of a novel method for converting the Japan Coma Scale to Glasgow Coma Scale","volume":"33","author":"Nakajima","year":"2023","journal-title":"Journal of Epidemiology"},{"issue":"5","key":"10.1016\/j.pnpbp.2025.111458_bb0620","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/j.psym.2020.04.012","article-title":"Treatment of Depression After Traumatic Brain Injury: A Systematic Review Focused on Pharmacological and Neuromodulatory Interventions","volume":"61","author":"Narapareddy","year":"2020","journal-title":"Psychosomatics"},{"issue":"1","key":"10.1016\/j.pnpbp.2025.111458_bb0625","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1038\/sj.mp.4002066","article-title":"Atypical antipsychotic-induced metabolic side effects: insights from receptor-binding profiles","volume":"13","author":"Nasrallah","year":"2008","journal-title":"Mol. Psychiatry"},{"issue":"7","key":"10.1016\/j.pnpbp.2025.111458_bb0630","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2023.e18342","article-title":"Mild traumatic brain injury as a pathological process","volume":"9","author":"Naumenko","year":"2023","journal-title":"Heliyon"},{"issue":"11","key":"10.1016\/j.pnpbp.2025.111458_bb0635","doi-asserted-by":"crossref","first-page":"1921","DOI":"10.1089\/neu.2009.0895","article-title":"Impact of early administration of sertraline on depressive symptoms in the first year after traumatic brain injury","volume":"26","author":"Novack","year":"2009","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.pnpbp.2025.111458_bb0640","article-title":"Preventive Services Task Force Evidence Syntheses, formerly Systematic Evidence Reviews, in Screening for Depression in Adults and Older Adults in Primary Care: An Updated Systematic","author":"O'Connor","year":"2009","journal-title":"Review"},{"issue":"3","key":"10.1016\/j.pnpbp.2025.111458_bb0645","article-title":"Update on Antidepressants","volume":"21","author":"O'Shanick","year":"2006","journal-title":"J. Head Trauma Rehabil."},{"issue":"14","key":"10.1016\/j.pnpbp.2025.111458_bb0650","doi-asserted-by":"crossref","first-page":"1620","DOI":"10.1089\/neu.2017.5379","article-title":"Depression in the first year after traumatic brain injury","volume":"35","author":"Ouellet","year":"2018","journal-title":"J. Neurotrauma"},{"issue":"2","key":"10.1016\/j.pnpbp.2025.111458_bb0655","doi-asserted-by":"crossref","first-page":"174","DOI":"10.2174\/0929867326666190124121725","article-title":"Obesity Therapy: How and Why?","volume":"27","author":"Paccosi","year":"2020","journal-title":"Curr. Med. Chem."},{"issue":"2","key":"10.1016\/j.pnpbp.2025.111458_bb0660","doi-asserted-by":"crossref","first-page":"109","DOI":"10.4103\/0975-5950.154810","article-title":"Trends in management of myofacial pain","volume":"5","author":"Pal","year":"2014","journal-title":"Natl J Maxillofac Surg"},{"issue":"3","key":"10.1016\/j.pnpbp.2025.111458_bb0665","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1097\/00001199-199906000-00002","article-title":"Sensitivity of three recent questionnaires to mild traumatic brain injury\u2014Related effects","volume":"14","author":"Paniak","year":"1999","journal-title":"J. Head Trauma Rehabil."},{"key":"10.1016\/j.pnpbp.2025.111458_bb0670","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1007\/s10571-016-0400-1","article-title":"Pathophysiology associated with traumatic brain injury: current treatments and potential novel therapeutics","volume":"37","author":"Pearn","year":"2017","journal-title":"Cell. Mol. Neurobiol."},{"issue":"14","key":"10.1016\/j.pnpbp.2025.111458_bb0675","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1089\/neu.2019.6735","article-title":"Pharmacological and Non-Pharmacological Interventions for Depression after Moderate-to-Severe Traumatic Brain Injury: A Systematic Review and Meta-Analysis","volume":"37","author":"Peppel","year":"2020","journal-title":"J. Neurotrauma"},{"issue":"11","key":"10.1016\/j.pnpbp.2025.111458_bb0680","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1089\/neu.2017.5506","article-title":"Placebo effects in traumatic brain injury","volume":"35","author":"Polich","year":"2018","journal-title":"J. Neurotrauma"},{"issue":"5","key":"10.1016\/j.pnpbp.2025.111458_bb0685","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1017\/S0033291715002640","article-title":"Efficacy of motivational interviewing and cognitive behavioral therapy for anxiety and depression symptoms following traumatic brain injury","volume":"46","author":"Ponsford","year":"2016","journal-title":"Psychol. Med."},{"issue":"2","key":"10.1016\/j.pnpbp.2025.111458_bb0690","article-title":"Psychotropic prescribing in psychiatric disorders in neurological diseases: stroke, traumatic brain injury, multiple sclerosis, and epilepsy","volume":"77","author":"Pretorian","year":"2024","journal-title":"Psihiatru. ro"},{"issue":"3","key":"10.1016\/j.pnpbp.2025.111458_bb0695","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1002\/ana.22455","article-title":"Inflammation after trauma: microglial activation and traumatic brain injury","volume":"70","author":"Ramlackhansingh","year":"2011","journal-title":"Ann. Neurol."},{"issue":"3","key":"10.1016\/j.pnpbp.2025.111458_bb0700","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1176\/appi.neuropsych.11080188","article-title":"Diffusion tensor imaging atlas-based analyses in major depression after mild traumatic brain injury","volume":"24","author":"Rao","year":"2012","journal-title":"The Journal of neuropsychiatry and clinical neurosciences"},{"issue":"8","key":"10.1016\/j.pnpbp.2025.111458_bb0705","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1177\/0269881107083845","article-title":"An open-label study of citalopram for major depression following traumatic brain injury","volume":"22","author":"Rapoport","year":"2008","journal-title":"J. Psychopharmacol."},{"issue":"9","key":"10.1016\/j.pnpbp.2025.111458_bb0710","doi-asserted-by":"crossref","first-page":"16629","DOI":"10.4088\/JCP.09m05086blu","article-title":"A randomized controlled trial of antidepressant continuation for major depression following traumatic brain injury","volume":"71","author":"Rapoport","year":"2010","journal-title":"The Journal of clinical psychiatry"},{"issue":"16","key":"10.1016\/j.pnpbp.2025.111458_bb0715","doi-asserted-by":"crossref","first-page":"3530","DOI":"10.1002\/jnr.22510","article-title":"Increase in blood-brain barrier permeability, oxidative stress, and activated microglia in a rat model of blast-induced traumatic brain injury","volume":"88","author":"Readnower","year":"2010","journal-title":"J. Neurosci. Res."},{"issue":"1","key":"10.1016\/j.pnpbp.2025.111458_bb0720","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/S0003-9993(98)90215-5","article-title":"Depression following traumatic brain injury","volume":"79","author":"Rosenthal","year":"1998","journal-title":"Arch. Phys. Med. Rehabil."},{"issue":"7","key":"10.1016\/j.pnpbp.2025.111458_bb0725","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1176\/appi.ajp.2011.10111645","article-title":"Combining medications to enhance depression outcomes (CO-MED): acute and long-term outcomes of a single-blind randomized study","volume":"168","author":"Rush","year":"2011","journal-title":"Am. J. Psychiatry"},{"issue":"7","key":"10.1016\/j.pnpbp.2025.111458_bb0730","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1089\/neu.2008.0586","article-title":"Classification of traumatic brain injury for targeted therapies","volume":"25","author":"Saatman","year":"2008","journal-title":"J. Neurotrauma"},{"issue":"4","key":"10.1016\/j.pnpbp.2025.111458_bb0735","doi-asserted-by":"crossref","first-page":"253","DOI":"10.2344\/anpr-64-04-14","article-title":"Anesthetic Considerations for Patients on Antidepressant Therapy-Part I","volume":"64","author":"Saraghi","year":"2017","journal-title":"Anesth. Prog."},{"issue":"1","key":"10.1016\/j.pnpbp.2025.111458_bb0740","doi-asserted-by":"crossref","first-page":"75","DOI":"10.2190\/15AH-JB7Q-U94T-JEAF","article-title":"Antidepressants not effective in headache associated with minor closed head injury","volume":"18","author":"Saran","year":"1989","journal-title":"The International Journal of Psychiatry in Medicine"},{"key":"10.1016\/j.pnpbp.2025.111458_bb0745","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1007\/s00068-004-1394-9","article-title":"The role of neuroinflammation in traumatic brain injury","volume":"30","author":"Schmidt","year":"2004","journal-title":"European Journal of Trauma"},{"key":"10.1016\/j.pnpbp.2025.111458_bb0750","series-title":"StatPearls Publishing Copyright \u00a9 2025","author":"Sheffler","year":"2025"},{"key":"10.1016\/j.pnpbp.2025.111458_bb0755","series-title":"Serotonin and norepinephrine reuptake inhibitors","first-page":"145","author":"Shelton","year":"2019"},{"issue":"7","key":"10.1016\/j.pnpbp.2025.111458_bb0760","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1038\/nrneurol.2010.74","article-title":"Blood\u2013brain barrier breakdown as a therapeutic target in traumatic brain injury","volume":"6","author":"Shlosberg","year":"2010","journal-title":"Nat. Rev. Neurol."},{"issue":"6","key":"10.1016\/j.pnpbp.2025.111458_bb0765","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1176\/appi.ajp.2009.08111676","article-title":"Depression and cognitive complaints following mild traumatic brain injury","volume":"166","author":"Silver","year":"2009","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.pnpbp.2025.111458_bb0770","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12888-019-2076-9","article-title":"Antidepressants for depression after concussion and traumatic brain injury are still best practice","volume":"19","author":"Silverberg","year":"2019","journal-title":"BMC psychiatry"},{"issue":"1","key":"10.1016\/j.pnpbp.2025.111458_bb0775","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1080\/02699052.2017.1376756","article-title":"Prevalence of depression after TBI in a prospective cohort: The SHEFBIT study","volume":"32","author":"Singh","year":"2018","journal-title":"Brain Inj."},{"issue":"3","key":"10.1016\/j.pnpbp.2025.111458_bb0780","doi-asserted-by":"crossref","first-page":"556","DOI":"10.3171\/2009.9.JNS09626","article-title":"Prevalence and impact of diffuse axonal injury in patients with moderate and severe head injury: a cohort study of early magnetic resonance imaging findings and 1-year outcome","volume":"113","author":"Skandsen","year":"2010","journal-title":"J. Neurosurg."},{"issue":"3","key":"10.1016\/j.pnpbp.2025.111458_bb0785","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1176\/appi.neuropsych.18070158","article-title":"Pharmacotherapy effectiveness in treating depression after traumatic brain injury: a meta-analysis","volume":"31","author":"Slowinski","year":"2019","journal-title":"The Journal of neuropsychiatry and clinical neurosciences"},{"issue":"4","key":"10.1016\/j.pnpbp.2025.111458_bb0790","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1097\/00001199-200307000-00003","article-title":"Diffuse axonal injury in head trauma","volume":"18","author":"Smith","year":"2003","journal-title":"J. Head Trauma Rehabil."},{"issue":"4","key":"10.1016\/j.pnpbp.2025.111458_bb0795","doi-asserted-by":"crossref","DOI":"10.1016\/j.apmr.2025.01.329","article-title":"Adaptive Rock Climbing as a Recreational Therapy for Spinal Cord Injury and Brain Injury: Findings From a Mixed-Methods Pilot Study","volume":"106","author":"Smith","year":"2025","journal-title":"Arch. Phys. Med. Rehabil."},{"issue":"10","key":"10.1016\/j.pnpbp.2025.111458_bb0800","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1017\/S1092852900024020","article-title":"Mechanism of Action of Trazodone: a Multifunctional Drug","volume":"14","author":"Stahl","year":"2009","journal-title":"CNS Spectrums"},{"issue":"4","key":"10.1016\/j.pnpbp.2025.111458_bb0805","first-page":"159","article-title":"A Review of the Neuropharmacology of Bupropion, a Dual Norepinephrine and Dopamine Reuptake Inhibitor","volume":"6","author":"Stahl","year":"2004","journal-title":"Prim Care Companion J Clin Psychiatry"},{"issue":"3","key":"10.1016\/j.pnpbp.2025.111458_bb0810","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1001\/jamapsychiatry.2018.4288","article-title":"Risk of posttraumatic stress disorder and major depression in civilian patients after mild traumatic brain injury: a TRACK-TBI study","volume":"76","author":"Stein","year":"2019","journal-title":"JAMA psychiatry"},{"key":"10.1016\/j.pnpbp.2025.111458_bb0815","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/B978-0-444-63954-7.00003-3","article-title":"Mild traumatic brain injury and concussion: terminology and classification","volume":"158","author":"Sussman","year":"2018","journal-title":"Handb. Clin. Neurol."},{"issue":"2","key":"10.1016\/j.pnpbp.2025.111458_bb0820","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1089\/neu.1993.10.135","article-title":"Unilateral cortical contusion injury in the rat: vascular disruption and temporal development of cortical necrosis","volume":"10","author":"Sutton","year":"1993","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.pnpbp.2025.111458_bb0825","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1007\/s00701-005-0651-y","article-title":"A systematic review of brain injury epidemiology in Europe","volume":"148","author":"Tagliaferri","year":"2006","journal-title":"Acta Neurochir."},{"issue":"7872","key":"10.1016\/j.pnpbp.2025.111458_bb0830","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S0140-6736(74)91639-0","article-title":"Assessment of coma and impaired consciousness: a practical scale","volume":"304","author":"Teasdale","year":"1974","journal-title":"Lancet"},{"issue":"8","key":"10.1016\/j.pnpbp.2025.111458_bb0835","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1016\/j.arcmed.2014.11.006","article-title":"The blood\u2013brain barrier as a target in traumatic brain injury treatment","volume":"45","author":"Thal","year":"2014","journal-title":"Arch. Med. Res."},{"issue":"7","key":"10.1016\/j.pnpbp.2025.111458_bb0840","doi-asserted-by":"crossref","DOI":"10.4088\/JCP.11096tx4c","article-title":"MAOIs and depression treatment guidelines","volume":"73","author":"Thase","year":"2012","journal-title":"J Clin Psychiatry"},{"issue":"4","key":"10.1016\/j.pnpbp.2025.111458_bb0845","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1002\/phar.1576","article-title":"Combination therapy with monoamine oxidase inhibitors and other antidepressants or stimulants: strategies for the management of treatment-resistant depression","volume":"35","author":"Thomas","year":"2015","journal-title":"Pharmacotherapy"},{"issue":"10","key":"10.1016\/j.pnpbp.2025.111458_bb0850","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1001\/jama.282.10.954","article-title":"Trends in hospitalization associated with traumatic brain injury","volume":"282","author":"Thurman","year":"1999","journal-title":"Jama"},{"issue":"2","key":"10.1016\/j.pnpbp.2025.111458_bb0855","doi-asserted-by":"crossref","DOI":"10.1097\/CNQ.0000000000000301","article-title":"Pharmacologic Treatment of Neurobehavioral Sequelae Following Traumatic Brain Injury","volume":"43","author":"Traeger","year":"2020","journal-title":"Crit. Care Nurs. Q."},{"issue":"10","key":"10.1016\/j.pnpbp.2025.111458_bb0860","first-page":"1245","article-title":"Adverse effects associated with selective serotonin reuptake inhibitors and tricyclic antidepressants: a meta-analysis","volume":"159","author":"Trindade","year":"1998","journal-title":"Cmaj"},{"issue":"1","key":"10.1016\/j.pnpbp.2025.111458_bb0865","first-page":"26","article-title":"Managing depressive disorders in patients with epilepsy","volume":"4","author":"Trivedi","year":"2007","journal-title":"Psychiatry (Edgmont)"},{"issue":"7433","key":"10.1016\/j.pnpbp.2025.111458_bb0870","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1038\/nature11740","article-title":"Dopamine neurons modulate neural encoding and expression of depression-related behaviour","volume":"493","author":"Tye","year":"2013","journal-title":"Nature"},{"issue":"10","key":"10.1016\/j.pnpbp.2025.111458_bb0875","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1176\/ajp.152.10.1493","article-title":"Psychiatric disorders and functional disability in outpatients with traumatic brain injuries","volume":"152","author":"Uomoto","year":"1995","journal-title":"Am. J. Psychiatry"},{"issue":"5","key":"10.1016\/j.pnpbp.2025.111458_bb0880","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1001\/jamaneurol.2016.0091","article-title":"Pathophysiologic Mechanisms of Cerebral Ischemia and Diffusion Hypoxia in Traumatic Brain Injury","volume":"73","author":"Veenith","year":"2016","journal-title":"JAMA Neurology"},{"issue":"5","key":"10.1016\/j.pnpbp.2025.111458_bb0885","doi-asserted-by":"crossref","first-page":"341","DOI":"10.2165\/00002512-199813050-00002","article-title":"Monoamine oxidase inhibitors. A perspective on their use in the elderly","volume":"13","author":"Volz","year":"1998","journal-title":"Drugs Aging"},{"issue":"4","key":"10.1016\/j.pnpbp.2025.111458_bb0890","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1002\/ana.20611","article-title":"Validation of a new coma scale: the FOUR score","volume":"58","author":"Wijdicks","year":"2005","journal-title":"Annals of Neurology: Official Journal of the American Neurological Association and the Child Neurology Society"},{"issue":"2","key":"10.1016\/j.pnpbp.2025.111458_bb0895","doi-asserted-by":"crossref","DOI":"10.1097\/00004714-199004000-00009","article-title":"The Incidence of Seizures during Tricyclic Antidepressant Drug Treatment in a Brain-Injured Population","volume":"10","author":"Wroblewski","year":"1990","journal-title":"J. Clin. Psychopharmacol."},{"issue":"22","key":"10.1016\/j.pnpbp.2025.111458_bb0900","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000006989","article-title":"Tricyclic antidepressants for preventing migraine in adults","volume":"96","author":"Xu","year":"2017","journal-title":"Medicine (Baltimore)"},{"issue":"4","key":"10.1016\/j.pnpbp.2025.111458_bb0905","doi-asserted-by":"crossref","first-page":"3260","DOI":"10.1039\/C5CP05771J","article-title":"Identification of the inhibitory mechanism of FDA approved selective serotonin reuptake inhibitors: an insight from molecular dynamics simulation study","volume":"18","author":"Xue","year":"2016","journal-title":"Phys. Chem. Chem. Phys."},{"issue":"1\u20132","key":"10.1016\/j.pnpbp.2025.111458_bb0910","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/S0161-813X(03)00097-4","article-title":"Clinical pharmacology of MAO inhibitors: safety and future","volume":"25","author":"Yamada","year":"2004","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.pnpbp.2025.111458_bb0915","series-title":"Seminars in speech and language","article-title":"Behavioral and social interventions for individuals with traumatic brain injury: A summary of the research with clinical implications","author":"Ylvisaker","year":"2005"},{"key":"10.1016\/j.pnpbp.2025.111458_bb0920","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.brainres.2009.11.052","article-title":"Unilateral lesion of the nigrostriatal pathway decreases the response of interneurons in medial prefrontal cortex to 5-HT2A\/2C receptor stimulation in the rat","volume":"1312","author":"Zhang","year":"2010","journal-title":"Brain Res."},{"key":"10.1016\/j.pnpbp.2025.111458_bb0925","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1742-2094-10-106","article-title":"Anti-inflammatory and immunomodulatory mechanisms of mesenchymal stem cell transplantation in experimental traumatic brain injury","volume":"10","author":"Zhang","year":"2013","journal-title":"J. Neuroinflammation"}],"container-title":["Progress in Neuro-Psychopharmacology and Biological Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S027858462500212X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S027858462500212X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T19:29:18Z","timestamp":1765913358000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S027858462500212X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":185,"alternative-id":["S027858462500212X"],"URL":"https:\/\/doi.org\/10.1016\/j.pnpbp.2025.111458","relation":{},"ISSN":["0278-5846"],"issn-type":[{"value":"0278-5846","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Updates on first- and second-generation antidepressants used in the treatment of traumatic brain injury-induced depression","name":"articletitle","label":"Article Title"},{"value":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pnpbp.2025.111458","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"111458"}}