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Med."},{"key":"10.1016\/j.pnpbp.2025.111490_bb0345","doi-asserted-by":"crossref","first-page":"7654","DOI":"10.1523\/JNEUROSCI.0091-13.2013","article-title":"Maternal immune activation during gestation interacts with Disc1 point mutation to exacerbate schizophrenia-related behaviors in mice","volume":"33","author":"Lipina","year":"2013","journal-title":"J. Neurosci."},{"key":"10.1016\/j.pnpbp.2025.111490_bb0350","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1007\/s10519-007-9164-1","article-title":"Identification of genetic and epigenetic variations in a rat model for neurodevelopmental disorders","volume":"37","author":"van Loo","year":"2007","journal-title":"Behav. Genet."},{"key":"10.1016\/j.pnpbp.2025.111490_bb0355","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41467-020-16218-4","article-title":"Interneuron hypomyelination is associated with cognitive inflexibility in a rat model of schizophrenia","volume":"11","author":"Maas","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.pnpbp.2025.111490_bb0360","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/j.bbi.2012.01.011","article-title":"Maternal immune activation yields offspring displaying mouse versions of the three core symptoms of autism","volume":"26","author":"Malkova","year":"2012","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.pnpbp.2025.111490_bb0365","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1038\/s41398-020-00890-7","article-title":"Intranasal oxytocin increases heart-rate variability in men at clinical high risk for psychosis: a proof-of-concept study","volume":"10","author":"Martins","year":"2020","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.pnpbp.2025.111490_bb0370","doi-asserted-by":"crossref","DOI":"10.1038\/tp.2017.80","article-title":"Maternal immune activation results in complex microglial transcriptome signature in the adult offspring that is reversed by minocycline treatment","volume":"7","author":"Mattei","year":"2017","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.pnpbp.2025.111490_bb0375","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.biopsych.2013.07.011","article-title":"Prenatal poly(I:C) exposure and other developmental immune activation models in rodent systems","volume":"75","author":"Meyer","year":"2014","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.pnpbp.2025.111490_bb0380","doi-asserted-by":"crossref","first-page":"4752","DOI":"10.1523\/JNEUROSCI.0099-06.2006","article-title":"The time of prenatal immune challenge determines the specificity of inflammation-mediated brain and behavioral pathology","volume":"26","author":"Meyer","year":"2006","journal-title":"J. Neurosci."},{"key":"10.1016\/j.pnpbp.2025.111490_bb0385","first-page":"241","article-title":"The neurodevelopmental impact of prenatal infections at different times of pregnancy: the earlier the worse?","volume":"13","author":"Meyer","year":"2007","journal-title":"Neuroscience"},{"key":"10.1016\/j.pnpbp.2025.111490_bb0390","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1038\/sj.mp.4002042","article-title":"Adult behavioral and pharmacological dysfunctions following disruption of the fetal brain balance between pro-inflammatory and IL-10-mediated anti-inflammatory signaling","volume":"13","author":"Meyer","year":"2008","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.pnpbp.2025.111490_bb0395","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.molmed.2016.01.006","article-title":"Molecular risk factors for schizophrenia","volume":"22","author":"Modai","year":"2016","journal-title":"Trends Mol. Med."},{"key":"10.1016\/j.pnpbp.2025.111490_bb0400","article-title":"Characterizing maternal isolation-induced ultrasonic vocalizations in a gene\u2013environment interaction rat model for autism","volume":"e12841","author":"M\u00f6hrle","year":"2023","journal-title":"Genes, Brain Behav"},{"key":"10.1016\/j.pnpbp.2025.111490_bb0405","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.schres.2014.07.048","article-title":"Deficits in anticipatory but not consummatory pleasure in people with recent-onset schizophrenia spectrum disorders","volume":"159","author":"Mote","year":"2014","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.pnpbp.2025.111490_bb0410","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.bbi.2018.09.005","article-title":"Evolution of a maternal immune activation (mIA) model in rats: early developmental effects","volume":"75","author":"Murray","year":"2019","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.pnpbp.2025.111490_bb0415","doi-asserted-by":"crossref","DOI":"10.1017\/S1461145707008401","article-title":"Oxidative stress in psychiatric disorders: evidence base and therapeutic implications","author":"Ng","year":"2008","journal-title":"Int. J. Neuropsychopharmacol."},{"key":"10.1016\/j.pnpbp.2025.111490_bb0420","doi-asserted-by":"crossref","first-page":"1934","DOI":"10.2174\/1570159X21666230221093644","article-title":"Neurobehavioral profiles of six genetically-based rat models of schizophrenia- related symptoms","volume":"21","author":"Oliveras","year":"2023","journal-title":"Curr. Neuropharmacol."},{"key":"10.1016\/j.pnpbp.2025.111490_bb0425","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1038\/s41467-019-14122-0","article-title":"Synaptic density marker SV2A is reduced in schizophrenia patients and unaffected by antipsychotics in rats","volume":"11","author":"Onwordi","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.pnpbp.2025.111490_bb0430","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1038\/s41380-018-0041-5","article-title":"Synaptic loss in schizophrenia: a meta-analysis and systematic review of synaptic protein and mRNA measures","volume":"24","author":"Osimo","year":"2019","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.pnpbp.2025.111490_bb0435","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.1126\/science.1202529","article-title":"Synaptic pruning by microglia is necessary for Normal brain development","volume":"333","author":"Paolicelli","year":"2011","journal-title":"Science (80)"},{"key":"10.1016\/j.pnpbp.2025.111490_bb0440","doi-asserted-by":"crossref","DOI":"10.1016\/j.physbeh.2020.113113","article-title":"Effects of prenatal exposure to valproic acid or poly(I:C) on ultrasonic vocalizations in rat pups: the role of social cues","volume":"225","author":"Potasiewicz","year":"2020","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.pnpbp.2025.111490_bb0445","first-page":"10","article-title":"Oxytocin as a modulator of synaptic plasticity: implications for neurodevelopmental disorders","author":"Rajamani","year":"2018","journal-title":"Front. Synaptic Neurosci."},{"key":"10.1016\/j.pnpbp.2025.111490_bb0450","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.neubiorev.2014.11.005","article-title":"Mitochondrial dysfunction in schizophrenia: pathways, mechanisms and implications","volume":"48","author":"Rajasekaran","year":"2015","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.pnpbp.2025.111490_bb0455","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1007\/s11517-006-0119-0","article-title":"Heart rate variability: a review","volume":"44","author":"Rajendra Acharya","year":"2006","journal-title":"Med. Biol. Eng. Comput."},{"key":"10.1016\/j.pnpbp.2025.111490_bb0460","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.ynstr.2016.02.007","article-title":"Maternal immune activation epigenetically regulates hippocampal serotonin transporter levels","volume":"4","author":"Reisinger","year":"2016","journal-title":"Neurobiol. Stress"},{"key":"10.1016\/j.pnpbp.2025.111490_bb0465","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1038\/sj.ejhg.5201571","article-title":"Molecular genetic studies of schizophrenia","volume":"14","author":"Riley","year":"2006","journal-title":"Eur. J. Hum. Genet."},{"key":"10.1016\/j.pnpbp.2025.111490_bb0470","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1038\/nature13595","article-title":"Biological insights from 108 schizophrenia-associated genetic loci","volume":"511","author":"Ripke","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.pnpbp.2025.111490_bb0475","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0006-8993(95)01379-2","article-title":"Rats bred for enhanced apomorphine susceptibility have elevated tyrosine hydroxylase mRNA and dopamine D2-receptor binding sites in nigrostriatal and tuberoinfundibular dopamine systems","volume":"710","author":"Rots","year":"1996","journal-title":"Brain Res."},{"key":"10.1016\/j.pnpbp.2025.111490_bb0480","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0044816","article-title":"Comprehensive analysis of ultrasonic vocalizations in a mouse model of fragile X syndrome reveals limited, call type specific deficits","volume":"7","author":"Roy","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.pnpbp.2025.111490_bb0485","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.brainresbull.2019.02.005","article-title":"Cumulative multiple early life hits- a potent threat leading to neurological disorders","volume":"147","author":"Sarkar","year":"2019","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.pnpbp.2025.111490_bb0490","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1038\/nature11015","article-title":"Autistic-like behaviours and hyperactivity in mice lacking ProSAP1\/Shank2","volume":"486","author":"Schmeisser","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.pnpbp.2025.111490_bb0495","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1038\/npp.2014.95","article-title":"Neurodevelopment, GABA system dysfunction, and schizophrenia","volume":"40","author":"Schmidt","year":"2014","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.pnpbp.2025.111490_bb0500","article-title":"Oxytocin effects on resting-state heart rate variability in women: the role of childhood rearing experiences","volume":"3","author":"Schoormans","year":"2020","journal-title":"Compr. Psychoneuroendocrinol."},{"key":"10.1016\/j.pnpbp.2025.111490_bb0505","doi-asserted-by":"crossref","first-page":"e240","DOI":"10.1038\/tp.2013.16","article-title":"Maternal immune activation and strain specific interactions in the development of autism-like behaviors in mice","volume":"3","author":"Schwartzer","year":"2013","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.pnpbp.2025.111490_bb0510","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1177\/0956797612469210","article-title":"An upside to adversity?: moderate cumulative lifetime adversity is associated with resilient responses in the face of controlled stressors","volume":"24","author":"Seery","year":"2013","journal-title":"Psychol. Sci."},{"key":"10.1016\/j.pnpbp.2025.111490_bb0515","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1038\/nature16549","article-title":"Schizophrenia risk from complex variation of complement component 4","volume":"530","author":"Sekar","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.pnpbp.2025.111490_bb0520","doi-asserted-by":"crossref","DOI":"10.1038\/srep34240","article-title":"Increased GABA B receptor signaling in a rat model for schizophrenia","volume":"6","author":"Selten","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.pnpbp.2025.111490_bb0525","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.bbr.2007.02.016","article-title":"Acquisition and expression of a socially mediated separation response","volume":"182","author":"Shair","year":"2007","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.pnpbp.2025.111490_bb0530","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1037\/a0024945","article-title":"Anticipatory pleasure predicts motivation for reward in major depression","volume":"121","author":"Sherdell","year":"2012","journal-title":"J. Abnorm. Psychol."},{"key":"10.1016\/j.pnpbp.2025.111490_bb0535","doi-asserted-by":"crossref","DOI":"10.1038\/s41537-020-0102-z","article-title":"The clinical course of schizophrenia in women and men\u2014a nation-wide cohort study","volume":"6","author":"Sommer","year":"2020","journal-title":"NPJ Schizophr."},{"key":"10.1016\/j.pnpbp.2025.111490_bb0540","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1038\/s41537-021-00151-6","article-title":"Autonomic nervous system dysfunction in schizophrenia: impact on cognitive and metabolic health","volume":"7","author":"Stogios","year":"2021","journal-title":"NPJ Schizophr."},{"key":"10.1016\/j.pnpbp.2025.111490_bb0545","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1007\/s00213-017-4776-5","article-title":"N-acetyl cysteine reverses bio-behavioural changes induced by prenatal inflammation, adolescent methamphetamine exposure and combined challenges","volume":"235","author":"Swanepoel","year":"2018","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.pnpbp.2025.111490_bb0550","doi-asserted-by":"crossref","DOI":"10.1016\/j.schres.2013.05.028","article-title":"Definition and description of schizophrenia in the DSM-5","author":"Tandon","year":"2013","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.pnpbp.2025.111490_bb0555","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/S0165-0327(00)00338-4","article-title":"A model of neurovisceral integration in emotion regulation and dysregulation","volume":"61","author":"Thayer","year":"2000","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.pnpbp.2025.111490_bb0560","doi-asserted-by":"crossref","unstructured":"Trubetskoy, V., Pardi\u00f1as, A.F., Qi, T., Panagiotaropoulou, G., Awasthi, S., Bigdeli, T.B., Bryois, J., Chen, C.-Y., Dennison, C.A., Hall, L.S., Lam, M., Watanabe, K., Frei, O., Ge, T., Harwood, J.C., Koopmans, F., Magnusson, S., Richards, A.L., Sidorenko, J., Wu, Y., Zeng, J., Grove, J., Kim, M., Li, Z., Voloudakis, G., Zhang, W., Adams, M., Agartz, I., Atkinson, E.G., Agerbo, E., Al Eissa, M., Albus, M., Alexander, M., Alizadeh, B.Z., Alptekin, K., Als, T.D., Amin, F., Arolt, V., Arrojo, M., Athanasiu, L., Azevedo, M.H., Bacanu, S.A., Bass, N.J., Begemann, M., Belliveau, R.A., Bene, J., Benyamin, B., Bergen, S.E., Blasi, G., Bobes, J., Bonassi, S., Braun, A., Bressan, R.A., Bromet, E.J., Bruggeman, R., Buckley, P.F., Buckner, R.L., Bybjerg-Grauholm, J., Cahn, W., Cairns, M.J., Calkins, M.E., Carr, V.J., Castle, D., Catts, S. V, Chambert, K.D., Chan, R.C.K., Chaumette, B., Cheng, W., Cheung, E.F.C., Chong, S.A., Cohen, D., Consoli, A., Cordeiro, Q., Costas, J., Curtis, C., Davidson, M., Davis, K.L., de Haan, L., Degenhardt, F., DeLisi, L.E., Demontis, D., Dickerson, F., Dikeos, D., Dinan, T., Djurovic, S., Duan, J., Ducci, G., Dudbridge, F., Eriksson, J.G., Fa\u00f1an\u00e1s, L., Faraone, S. V, Fiorentino, A., Forstner, A., Frank, J., Freimer, N.B., Fromer, M., Frustaci, A., Gadelha, A., Genovese, G., Gershon, E.S., Giannitelli, M., Giegling, I., Giusti-Rodr\u00edguez, P., Godard, S., Goldstein, J.I., Gonz\u00e1lez Pe\u00f1as, J., Gonz\u00e1lez-Pinto, A., Gopal, S., Gratten, J., Green, M.F., Greenwood, T.A., Guillin, O., G\u00fcl\u00f6ks\u00fcz, S., Gur, R.E., Gur, R.C., Guti\u00e9rrez, B., Hahn, E., Hakonarson, H., Haroutunian, V., Hartmann, A.M., Harvey, C., Hayward, C., Henskens, F.A., Herms, S., Hoffmann, P., Howrigan, D.P., Ikeda, M., Iyegbe, C., Joa, I., Juli\u00e0, A., K\u00e4hler, A.K., Kam-Thong, T., Kamatani, Y., Karachanak-Yankova, S., Kebir, O., Keller, M.C., Kelly, B.J., Khrunin, A., Kim, S.-W., Klovins, J., Kondratiev, N., Konte, B., Kraft, J., Kubo, M., Ku\u010dinskas, V., Ku\u010dinskiene, Z.A., Kusumawardhani, A., Kuzelova-Ptackova, H., Landi, S., Lazzeroni, L.C., Lee, P.H., Legge, S.E., Lehrer, D.S., Lencer, R., Lerer, B., Li, M., Lieberman, J., Light, G.A., Limborska, S., Liu, C.-M., L\u00f6nnqvist, J., Loughland, C.M., Lubinski, J., Luykx, J.J., Lynham, A., Macek, M., Mackinnon, A., Magnusson, P.K.E., Maher, B.S., Maier, W., Malaspina, D., Mallet, J., Marder, S.R., Marsal, S., Martin, A.R., Martorell, L., Mattheisen, M., McCarley, R.W., McDonald, C., McGrath, J.J., Medeiros, H., Meier, S., Melegh, B., Melle, I., Mesholam-Gately, R.I., Metspalu, A., Michie, P.T., Milani, L., Milanova, V., Mitjans, M., Molden, E., Molina, E., Molto, M.D., Mondelli, V., Moreno, C., Morley, C.P., Muntan\u00e9, G., Murphy, K.C., Myin-Germeys, I., Nenadi\u0107, I., Nestadt, G., Nikitina-Zake, L., Noto, C., Nuechterlein, K.H., O'Brien, N.L., O'Neill, F.A., Oh, S.-Y., Olincy, A., Ota, V.K., Pantelis, C., Papadimitriou, G.N., Parellada, M., Paunio, T., Pellegrino, R., Periyasamy, S., Perkins, D.O., Pfuhlmann, B., Pietil\u00e4inen, O., Pimm, J., Porteous, D., Powell, J., Quattrone, D., Quested, D., Radant, A.D., Rampino, A., Rapaport, M.H., Rautanen, A., Reichenberg, A., Roe, C., Roffman, J.L., Roth, J., Rothermundt, M., Rutten, B.P.F., Saker-Delye, S., Salomaa, V., Sanjuan, J., Santoro, M.L., Savitz, A., Schall, U., Scott, R.J., Seidman, L.J., Sharp, S.I., Shi, J., Siever, L.J., Sigurdsson, E., Sim, K., Skarabis, N., Slominsky, P., So, H.-C., Sobell, J.L., S\u00f6derman, E., Stain, H.J., Steen, N.E., Steixner-Kumar, A.A., St\u00f6gmann, E., Stone, W.S., Straub, R.E., Streit, F., Strengman, E., Stroup, T.S., Subramaniam, M., Sugar, C.A., Suvisaari, J., Svrakic, D.M., Swerdlow, N.R., Szatkiewicz, J.P., Ta, T.M.T., Takahashi, A., Terao, C., Thibaut, F., Toncheva, D., Tooney, P.A., Torretta, S., Tosato, S., Tura, G.B., Turetsky, B.I., \u00dc\u00e7ok, A., Vaaler, A., van Amelsvoort, T., van Winkel, R., Veijola, J., Waddington, J., Walter, H., Waterreus, A., Webb, B.T., Weiser, M., Williams, N.M., Witt, S.H., Wormley, B.K., Wu, J.Q., Xu, Z., Yolken, R., Zai, C.C., Zhou, W., Zhu, F., Zimprich, F., Atba\u015fo\u011flu, E.C., Ayub, M., Benner, C., Bertolino, A., 2022. Mapping genomic loci implicates genes and synaptic biology in schizophrenia. Nature 604, 502\u2013508. Doi: https:\/\/doi.org\/10.1038\/s41586-022-04434-5.","DOI":"10.1038\/s41586-022-04434-5"},{"key":"10.1016\/j.pnpbp.2025.111490_bb0565","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyt.2014.00048","article-title":"Gene-environment interactions in severe mental illness","author":"Uher","year":"2014","journal-title":"Front. Psychiatry"},{"key":"10.1016\/j.pnpbp.2025.111490_bb0570","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/j.bbr.2009.10.042","article-title":"Gene expression profiling in brain regions of a rat model displaying schizophrenia-related features","volume":"207","author":"Van Schijndel","year":"2010","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.pnpbp.2025.111490_bb0575","doi-asserted-by":"crossref","DOI":"10.3389\/fnbeh.2014.00268","article-title":"Maternal care affects the phenotype of a rat model for schizophrenia","volume":"8","author":"van Vugt","year":"2014","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.pnpbp.2025.111490_bb0580","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1523\/JNEUROSCI.4831-11.2012","article-title":"Prenatal immune activation interacts with genetic Nurr1 deficiency in the development of attentional impairments","volume":"32","author":"Vuillermot","year":"2012","journal-title":"J. Neurosci."},{"key":"10.1016\/j.pnpbp.2025.111490_bb0585","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1177\/0963721410377744","article-title":"Neurodevelopment and schizophrenia: broadening the focus","volume":"19","author":"Walker","year":"2010","journal-title":"Curr. Dir. Psychol. Sci."},{"key":"10.1016\/j.pnpbp.2025.111490_bb0590","doi-asserted-by":"crossref","first-page":"3500","DOI":"10.1073\/pnas.83.10.3500","article-title":"Synaptophysin: a marker protein for neuroendocrine cells and neoplasms","volume":"83","author":"Wiedenmann","year":"1986","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.pnpbp.2025.111490_bb0595","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1097\/FBP.0000000000000688","article-title":"Preweaning environmental enrichment alters neonatal ultrasonic vocalisations in a rat model for prenatal infections","volume":"33","author":"Wilkin-Krug","year":"2022","journal-title":"Behav. 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