{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T05:00:15Z","timestamp":1778562015154,"version":"3.51.4"},"reference-count":95,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2005,12,1]],"date-time":"2005-12-01T00:00:00Z","timestamp":1133395200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Primary Care: Clinics in Office Practice"],"published-print":{"date-parts":[[2005,12]]},"DOI":"10.1016\/j.pop.2005.09.001","type":"journal-article","created":{"date-parts":[[2007,1,10]],"date-time":"2007-01-10T14:28:46Z","timestamp":1168439326000},"page":"1057-1081","source":"Crossref","is-referenced-by-count":5,"title":["Management of Coronary Heart Disease: Stable Angina, Acute Coronary Syndrome, Myocardial Infarction"],"prefix":"10.1016","volume":"32","author":[{"given":"Shalin B.","family":"Mehta","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen-Chih","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.pop.2005.09.001_bib1","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/S0735-1097(83)80072-2","article-title":"Computer-assisted diagnosis in the noninvasive evaluation of patients with suspected coronary disease","volume":"1","author":"Diamond","year":"1983","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.pop.2005.09.001_bib2","unstructured":"Gibbons RJ, Abrams J, Chatterjee K, et al. ACC\/AHA 2002 guideline update for the management of patients with chronic stable angina: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines (Committee to Update the 1999 Guidelines for the Management of Patients with Chronic Stable Angina). 2002. Available at: www.acc.org\/clinical\/guidelines\/stable\/stable.pdf. Accessed May 1, 2005."},{"key":"10.1016\/j.pop.2005.09.001_bib3","series-title":"Heart disease: a textbook of cardiovascular medicines","first-page":"1232","article-title":"Unstable angina","author":"Cannon","year":"2001"},{"key":"10.1016\/j.pop.2005.09.001_bib4","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1056\/NEJM199605163342007","article-title":"The evaluation of chest pain in women","volume":"334","author":"Douglas","year":"1996","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pop.2005.09.001_bib5","unstructured":"Braunwald E, Antman EM, Beasley JW, et al. American College of Cardiology\/American Heart Association Committee on the Management of Patients With Unstable Angina. ACC\/AHA 2002 guideline update for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines (Committee on the Management of Patients With Unstable Angina). 2002. Available at: http:\/\/www.acc.org\/clinical\/guidelines\/unstable\/incorporated\/index.htm. Accessed May 1, 2005."},{"key":"10.1016\/j.pop.2005.09.001_bib6","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1001\/jama.283.7.897","article-title":"The International Registry of Acute Aortic Dissection (IRAD): new insights into an old disease","volume":"283","author":"Hagan","year":"2000","journal-title":"JAMA"},{"key":"10.1016\/j.pop.2005.09.001_bib7","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1001\/archinte.1985.00360010085013","article-title":"Acute chest pain in the emergency room. Identification and examination of low-risk patients","volume":"145","author":"Lee","year":"1985","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.pop.2005.09.001_bib8","first-page":"345","article-title":"Episodes of care for chest pain: a preliminary report from MIRNET. Michigan Research Network","volume":"38","author":"Klinkman","year":"1994","journal-title":"J Fam Prac"},{"key":"10.1016\/j.pop.2005.09.001_bib9","series-title":"Heart disease: a textbook of cardiovascular medicines","first-page":"1272","article-title":"Chronic coronary artery disease","author":"Gersh","year":"2001"},{"key":"10.1016\/j.pop.2005.09.001_bib10","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1161\/circ.54.3.947585","article-title":"Grading of angina pectoris","volume":"54","author":"Campeau","year":"1976","journal-title":"Circulation"},{"key":"10.1016\/j.pop.2005.09.001_bib11","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1161\/01.CIR.80.2.410","article-title":"Unstable angina: a classification","volume":"80","author":"Braunwald","year":"1989","journal-title":"Circulation"},{"key":"10.1016\/j.pop.2005.09.001_bib12","series-title":"Ischemic heart disease: a rational basis for clinical practice and clinical research","author":"Maseri","year":"1995"},{"key":"10.1016\/j.pop.2005.09.001_bib13","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/S0025-6196(12)61257-9","article-title":"Coronary heart disease in residents of Rochester, Minnesota, IV. Prognostic value of the resting electrocardiogram at the time of initial diagnosis of angina pectoris","volume":"59","author":"Connolly","year":"1984","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.pop.2005.09.001_bib14","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1067\/mje.2001.112110","article-title":"Hyperventilation and cold-pressor stress echocardiography for noninvasive diagnosis of coronary artery spasm","volume":"14","author":"Hirano","year":"2001","journal-title":"J Am Soc Echocardiogr"},{"key":"10.1016\/j.pop.2005.09.001_bib15","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1097\/00001573-200309000-00011","article-title":"Does electron beam computer tomography provide added value in the diagnosis of coronary artery disease?","volume":"18","author":"Fuseini","year":"2003","journal-title":"Curr Opin Cardiol"},{"key":"10.1016\/j.pop.2005.09.001_bib16","unstructured":"Cheitlin MD, Armstrong WF, Aurigemma GP, et al. American College of Cardiology, American Heart Association, ASE. ACC\/AHA\/ASE 2003 guideline update for the clinical application of echocardiography: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines (ACC\/AHA\/ASE Committee to Update the 1997 Guidelines for the Clinical Application of Echocardiography). Available at: www.acc.org\/clinical\/guidelines\/echo\/index.pdf, 2003. Accessed May 1, 2005."},{"key":"10.1016\/j.pop.2005.09.001_bib17","unstructured":"Gibbons RJ, Balady GJ, Bricker JT, Chaitman BR, Fletcher GF, Froelicher VF, et al. American College of Cardiology\/American Heart Association Task Force on Practice Guidelines. Committee to Update the 1997 Exercise Testing Guidelines. ACC\/AHA 2002 guideline update for exercise testing: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines (Committee on Exercise Testing). 2002. Available at: www.acc.org\/clinical\/guidelines\/exercise\/dirIndex.htm. Accessed May 1, 2005."},{"key":"10.1016\/j.pop.2005.09.001_bib18","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1056\/NEJM197906143002402","article-title":"Analysis of probability as an aid in the clinical diagnosis of coronary-artery disease","volume":"300","author":"Diamond","year":"1979","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pop.2005.09.001_bib19","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1016\/0002-9343(83)90406-0","article-title":"Estimating the likelihood of significant coronary artery disease","volume":"75","author":"Pryor","year":"1983","journal-title":"Am J Med"},{"key":"10.1016\/j.pop.2005.09.001_bib20","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/0002-9343(90)90090-Z","article-title":"Using the patient's history to estimate the probability of coronary artery disease: a comparison of primary care and referral practices","volume":"89","author":"Sox","year":"1990","journal-title":"Am J Med"},{"key":"10.1016\/j.pop.2005.09.001_bib21","doi-asserted-by":"crossref","first-page":"81","DOI":"10.7326\/0003-4819-118-2-199301150-00001","article-title":"Value of the history and physical in identifying patients at increased risk for coronary artery disease","volume":"118","author":"Pryor","year":"1993","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.pop.2005.09.001_bib22","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1161\/01.CIR.80.1.87","article-title":"Exercise-induced ST depression in the diagnosis of coronary artery disease: a meta-analysis","volume":"80","author":"Gianrossi","year":"1989","journal-title":"Circulation"},{"key":"10.1016\/j.pop.2005.09.001_bib23","unstructured":"Klocke FJ, Baird MG, Lorell BH, et al. American College of Cardiology, American Heart Association, American Society for Nuclear Cardiology. ACC\/AHA\/ASNC guidelines for the clinical use of cardiac radionuclide imaging: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines (ACC\/AHA\/ASNC Committee to Revise the 1995 Guidelines for the Clinical Use of Radionuclide Imaging). Available at http:\/\/www.acc.org\/clinical\/guidelines\/radio\/rni_fulltext.pdf, 2003. Accessed May 1, 2005."},{"key":"10.1016\/j.pop.2005.09.001_bib24","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1111\/j.1540-8175.1999.tb00140.x","article-title":"Advances in exercise echocardiography","volume":"16","author":"Marwick","year":"1999","journal-title":"Echocardiography"},{"key":"10.1016\/j.pop.2005.09.001_bib25","doi-asserted-by":"crossref","first-page":"25D","DOI":"10.1016\/0002-9149(95)90108-6","article-title":"Comparison of stress echocardiography and stress myocardial perfusion scintigraphy for diagnosing coronary artery disease and assessing its severity","volume":"75","author":"O'Keefe","year":"1995","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.pop.2005.09.001_bib26","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1136\/hrt.2004.044396","article-title":"British Society of Echocardiography. Stress echocardiography for the diagnosis and risk stratification of patients with suspected or known coronary artery disease: a critical appraisal. Supported by the British Society of Echocardiography","volume":"91","author":"Senior","year":"2005","journal-title":"Heart"},{"key":"10.1016\/j.pop.2005.09.001_bib27","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/0002-9343(84)90437-6","article-title":"Factors affecting sensitivity and specificity of exercise electrocardiography: multivariable analysis","volume":"77","author":"Hlatky","year":"1984","journal-title":"Am J Med"},{"key":"10.1016\/j.pop.2005.09.001_bib28","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1016\/0002-8703(95)90072-1","article-title":"Comparison of the sensitivity and specificity of exercise electrocardiography in biased and unbiased populations of men and women","volume":"130","author":"Morise","year":"1995","journal-title":"Am Heart J"},{"key":"10.1016\/j.pop.2005.09.001_bib29","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/S0025-6196(12)60573-4","article-title":"Selection of optimal drug therapy for the patient with angina pectoris","volume":"60","author":"Shub","year":"1985","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.pop.2005.09.001_bib30","doi-asserted-by":"crossref","first-page":"835","DOI":"10.7326\/0003-4819-114-10-835","article-title":"Low-dose aspirin therapy for chronic stable angina. A randomized, placebo-controlled clinical trial","volume":"114","author":"Ridker","year":"1991","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.pop.2005.09.001_bib31","first-page":"81","article-title":"Collaborative overview of randomised trials of antiplatelet therapy, I: prevention of death, myocardial infarction and stroke by prolonged antiplatelet therapy in various categories of patients","volume":"308","year":"1995","journal-title":"BMJ"},{"key":"10.1016\/j.pop.2005.09.001_bib32","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1136\/bmj.324.7329.71","article-title":"Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients","volume":"324","year":"2002","journal-title":"BMJ"},{"key":"10.1016\/j.pop.2005.09.001_bib33","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1016\/S0140-6736(96)09457-3","article-title":"A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE)","volume":"348","year":"1996","journal-title":"Lancet"},{"key":"10.1016\/j.pop.2005.09.001_bib34","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/0002-9149(91)90518-P","article-title":"Comparison of celiprolol and propranolol in stable angina pectoris. Celiprolol International Angina Study Group","volume":"67","author":"Frishman","year":"1991","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.pop.2005.09.001_bib35","doi-asserted-by":"crossref","first-page":"1730","DOI":"10.1136\/bmj.318.7200.1730","article-title":"Beta blockade after myocardial infarction: systematic review and meta regression analysis","volume":"318","author":"Freemantle","year":"1999","journal-title":"BMJ"},{"key":"10.1016\/j.pop.2005.09.001_bib36","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.pcad.2004.04.004","article-title":"Cardiovascular drug class specificity: beta-blockers","volume":"47","author":"Reiter","year":"2004","journal-title":"Prog Cardiovasc Dis"},{"key":"10.1016\/j.pop.2005.09.001_bib37","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/0002-9149(83)90113-3","article-title":"Detrimental effect of propranolol in patients with coronary arterial spasm countered by combination with diltiazem","volume":"52","author":"Tilmant","year":"1983","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.pop.2005.09.001_bib38","doi-asserted-by":"crossref","first-page":"897","DOI":"10.7326\/0003-4819-112-12-897","article-title":"Potentiation of cocaine induced coronary vasoconstriction by beta-adrenergic blockade","volume":"112","author":"Lange","year":"1990","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.pop.2005.09.001_bib39","doi-asserted-by":"crossref","first-page":"1927","DOI":"10.1001\/jama.281.20.1927","article-title":"Meta-analysis of trials comparing beta-blockers, calcium antagonists, and nitrates for stable angina","volume":"281","author":"Heidenreich","year":"1999","journal-title":"JAMA"},{"key":"10.1016\/j.pop.2005.09.001_bib40","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S0033-0620(97)80023-0","article-title":"Cocaine-induced myocardial ischemia and infarction: pathophysiology, recognition, and management","volume":"40","author":"Pitts","year":"1997","journal-title":"Prog Cardiovasc Dis"},{"key":"10.1016\/j.pop.2005.09.001_bib41","doi-asserted-by":"crossref","first-page":"350","DOI":"10.4037\/ajcc2004.13.4.350","article-title":"Prinzmetal's angina","volume":"13","author":"Keller","year":"2004","journal-title":"Am J Crit Care"},{"key":"10.1016\/j.pop.2005.09.001_bib42","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.1016\/S0140-6736(00)02262-5","article-title":"Diltiazem in acute myocardial infarction treated with thrombolytic agents: a randomised placebo-controlled trial. Incomplete Infarction Trial of European Research Collaborators Evaluating Prognosis Post-Thrombolysis (INTERCEPT)","volume":"355","author":"Boden","year":"2000","journal-title":"Lancet"},{"key":"10.1016\/j.pop.2005.09.001_bib43","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1056\/NEJM199610103351504","article-title":"Effect of amlodipine on morbidity and mortality in severe chronic heart failure. Prospective Randomized Amlodipine Survival Evaluation Study Group","volume":"335","author":"Packer","year":"1996","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pop.2005.09.001_bib44","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1161\/01.CIR.96.3.856","article-title":"Effect of the calcium antagonist felodipine as supplementary vasodilator therapy in patients with chronic heart failure treated with enalapril: V-HeFT III","volume":"96","author":"Cohn","year":"1997","journal-title":"Circulation"},{"key":"10.1016\/j.pop.2005.09.001_bib45","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1001\/jama.1995.03530080036038","article-title":"The risk of myocardial infarction associated with antihypertensive drug therapies","volume":"274","author":"Psaty","year":"1995","journal-title":"JAMA"},{"key":"10.1016\/j.pop.2005.09.001_bib46","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/0002-9343(83)90858-6","article-title":"Nitroglycerin and long-acting nitrates in clinical practice","volume":"74","author":"Abrams","year":"1983","journal-title":"Am J Med"},{"key":"10.1016\/j.pop.2005.09.001_bib47","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/0002-8703(85)90493-4","article-title":"Improved coronary supply: prevailing mechanism of action of nitrates in chronic stable angina","volume":"110","author":"Kaski","year":"1985","journal-title":"Am Heart J"},{"key":"10.1016\/j.pop.2005.09.001_bib48","doi-asserted-by":"crossref","first-page":"391","DOI":"10.2165\/00003495-198734030-00005","article-title":"Glyceryl trinitrate (nitroglycerin) and the organic nitrates. Choosing the method of administration","volume":"34","author":"Abrams","year":"1987","journal-title":"Drugs"},{"issue":"Suppl 1","key":"10.1016\/j.pop.2005.09.001_bib49","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1023\/A:1007750706831","article-title":"Oral nitrates: more than symptomatic therapy in coronary artery disease?","volume":"11","author":"Thadani","year":"1997","journal-title":"Cardiovasc Drugs Ther"},{"key":"10.1016\/j.pop.2005.09.001_bib50","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/S0735-1097(98)00656-1","article-title":"ACC\/AHA expert consensus document. Use of sildenafil (Viagra) in patients with cardiovascular disease","volume":"33","author":"Cheitlin","year":"1999","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.pop.2005.09.001_bib51","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1056\/NEJM199209033271001","article-title":"Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the Survival and Ventricular Enlargement trial","volume":"327","author":"Pfeffer","year":"1992","journal-title":"N Engl J Med"},{"issue":"8875","key":"10.1016\/j.pop.2005.09.001_bib52","first-page":"821","article-title":"Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure. The Acute Infarction Ramipril Efficacy (AIRE) Study Investigators","volume":"342","year":"1993","journal-title":"Lancet"},{"key":"10.1016\/j.pop.2005.09.001_bib53","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1056\/NEJM200001203420301","article-title":"Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators","volume":"342","author":"Yusuf","year":"2000","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pop.2005.09.001_bib54","doi-asserted-by":"crossref","first-page":"2058","DOI":"10.1056\/NEJMoa042739","article-title":"PEACE Trial Investigators. Angiotensin-converting-enzyme inhibition in stable coronary artery disease","volume":"351","author":"Braunwald","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pop.2005.09.001_bib55","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/S0140-6736(94)91963-1","article-title":"Effect of coronary artery bypass graft surgery on survival: overview of 10-year results from randomised trials by the Coronary Artery Bypass Graft Surgery Trialists Collaboration","volume":"344","author":"Yusuf","year":"1994","journal-title":"Lancet"},{"key":"10.1016\/j.pop.2005.09.001_bib56","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1056\/NEJM199201023260102","article-title":"A comparison of angioplasty with medical therapy in the treatment of single-vessel coronary artery disease. Veterans Affairs ACME Investigators","volume":"326","author":"Parisi","year":"1992","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pop.2005.09.001_bib57","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1056\/NEJMoa035071","article-title":"SIRIUS Investigators. Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery","volume":"349","author":"Moses","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pop.2005.09.001_bib58","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1056\/NEJMoa032441","article-title":"TAXUS-IV Investigators. A polymer-based, paclitaxel-eluting stent in patients with coronary artery disease","volume":"350","author":"Stone","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pop.2005.09.001_bib59","unstructured":"Braunwald E, Mark DB, Jones RH, et al. AHCPR clinical practice guideline no 10, unstable angina: diagnosis and management, May 1994. Unstable angina: diagnosis and management. Available at: http:\/\/www.ncbi.nlm.nih.gov\/books\/bv.fcgi?rid=hstat6.chapter.21322. Accessed May 1, 2005."},{"key":"10.1016\/j.pop.2005.09.001_bib60","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1001\/jama.284.7.835","article-title":"The TIMI risk score for unstable angina\/non-ST elevation MI: A method for prognostication and therapeutic decision making","volume":"284","author":"Antman","year":"2000","journal-title":"JAMA"},{"key":"10.1016\/j.pop.2005.09.001_bib61","doi-asserted-by":"crossref","first-page":"1879","DOI":"10.1056\/NEJM200106213442501","article-title":"Comparison of early invasive and conservative strategies in patients with unstable coronary syndromes treated with the glycoprotein IIb\/IIIa inhibitor tirofiban","volume":"344","author":"Cannon","year":"2001","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pop.2005.09.001_bib62","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1056\/NEJM198308183090703","article-title":"Protective effects of aspirin against acute myocardial infarction and death in men with unstable angina: results of a Veterans Administration Cooperative Study","volume":"309","author":"Lewis","year":"1983","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pop.2005.09.001_bib63","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1056\/NEJM198511283132201","article-title":"Aspirin, sulfinpyrazone, or both in unstable angina. Results of a Canadian multicenter trial","volume":"313","author":"Cairns","year":"1985","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pop.2005.09.001_bib64","doi-asserted-by":"crossref","first-page":"89","DOI":"10.2165\/00002018-199819020-00002","article-title":"Adverse haematological effects of ticlopidine: prevention, recognition and management","volume":"19","author":"Love","year":"1998","journal-title":"Drug Saf"},{"key":"10.1016\/j.pop.2005.09.001_bib65","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1056\/NEJMoa010746","article-title":"Clopidogrel in Unstable Angina to Prevent Recurrent Events Trial Investigators. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation","volume":"345","author":"Yusuf","year":"2001","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pop.2005.09.001_bib66","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1001\/jama.1996.03540100055028","article-title":"Adding heparin to aspirin reduces the incidence of myocardial infarction and death in patients with unstable angina, a meta-analysis","volume":"276","author":"Oler","year":"1996","journal-title":"JAMA"},{"key":"10.1016\/j.pop.2005.09.001_bib67","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1001\/jama.292.1.89","article-title":"Efficacy and bleeding complications among patients randomized to enoxaparin or unfractionated heparin for antithrombin therapy in non-ST-Segment elevation acute coronary syndromes: a systematic overview","volume":"292","author":"Petersen","year":"2004","journal-title":"JAMA"},{"key":"10.1016\/j.pop.2005.09.001_bib68","first-page":"2049","article-title":"Clinical outcomes of bivalirudin for ischemic heart disease","volume":"100","author":"Kong","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pop.2005.09.001_bib69","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1161\/01.CIR.89.4.1545","article-title":"Effect of tissue plasminogen activator and a comparison of early invasive and conservative strategies in unstable angina and non-Q-wave myocardial infarction results of the TIMI IIIB trial","volume":"89","author":"TIMI IIIB Investigators","year":"1994","journal-title":"Circulation"},{"issue":"Suppl 4","key":"10.1016\/j.pop.2005.09.001_bib70","doi-asserted-by":"crossref","first-page":"49S","DOI":"10.1016\/S0735-1097(02)02835-8","article-title":"Glycoprotein IIb\/IIIa inhibition in early intent-to-stent treatment of acute coronary syndromes: EPISTENT, ADMIRAL, CADILLAC, and TARGET","volume":"41","author":"Moliterno","year":"2003","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.pop.2005.09.001_bib71","doi-asserted-by":"crossref","first-page":"1893","DOI":"10.1056\/NEJMoa032292","article-title":"Valsartan in Acute Myocardial Infarction Trial Investigators. Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both","volume":"349","author":"Pfeffer","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pop.2005.09.001_bib72","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1016\/j.jacc.2004.07.002","article-title":"ACC\/AHA guidelines for the management of patients with ST-elevation myocardial infarction: executive summary: a report of the ACC\/AHA Task Force on Practice Guidelines","volume":"44","author":"Antman","year":"2004","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.pop.2005.09.001_bib73","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.1056\/NEJM200106213442503","article-title":"Platelet glycoprotein IIb\/IIIa inhibition with coronary stenting for acute myocardial infarction","volume":"344","author":"Montalescot","year":"2001","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pop.2005.09.001_bib74","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1016\/S0735-1097(03)00919-7","article-title":"ZWOLLE Myocardial Infarction Study Group. Symptom-onset-to-balloon time and mortality in patients with acute myocardial infarction treated by primary angioplasty","volume":"42","author":"De Luca","year":"2003","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.pop.2005.09.001_bib75","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1161\/01.CIR.0000121424.76486.20","article-title":"Time delay to treatment and mortality in primary angioplasty for acute myocardial infarction: every minute of delay counts","volume":"109","author":"De Luca","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.pop.2005.09.001_bib76","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/S0140-6736(94)91161-4","volume":"343","year":"1994","journal-title":"Lancet"},{"key":"10.1016\/j.pop.2005.09.001_bib77","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1016\/S0140-6736(05)80089-3","article-title":"Individual risk assessment for intracranial hemorrhage during thrombolytic therapy","volume":"342","author":"Simoons","year":"1993","journal-title":"Lancet"},{"key":"10.1016\/j.pop.2005.09.001_bib78","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1016\/S0735-1097(02)01878-8","article-title":"Zwolle Myocardial Infarction Study Group. Reperfusion therapy in elderly patients with acute myocardial infarction: a randomized comparison of primary angioplasty and thrombolytic therapy","volume":"39","author":"de Boer","year":"2002","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.pop.2005.09.001_bib79","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1016\/S0735-1097(98)00609-3","article-title":"Effect of angiotensin converting enzyme inhibition on sudden cardiac death in patients following acute myocardial infarction. A meta-analysis of randomized clinical trials","volume":"33","author":"Domanski","year":"1999","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.pop.2005.09.001_bib80","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1056\/NEJMoa010615","article-title":"Blood transfusion in elderly patients with acute myocardial infarction","volume":"345","author":"Wu","year":"2001","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pop.2005.09.001_bib81","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1056\/NEJMoa030207","article-title":"Eplerenone Post-Acute Myocardial Infarction Heart Failure Efficacy and Survival Study Investigators. Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction","volume":"348","author":"Pitt","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pop.2005.09.001_bib82","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1136\/bmj.287.6388.324","article-title":"Long term effect on mortality of stopping smoking after unstable angina and myocardial infarction","volume":"287","author":"Daly","year":"1983","journal-title":"Br Med J (Clin Res Ed)"},{"key":"10.1016\/j.pop.2005.09.001_bib83","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1056\/NEJM199903043400903","article-title":"A controlled trial of sustained-release bupropion, a nicotine patch, or both for smoking cessation","volume":"340","author":"Jorenby","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pop.2005.09.001_bib84","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1056\/NEJM199309303291401","article-title":"The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus","volume":"329","author":"The Diabetes Control and Complications Trial Research Group","year":"1993","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pop.2005.09.001_bib85","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1016\/S0002-9149(99)80683-3","article-title":"Effect of intensive diabetes management on macrovascular events and risk factors in the Diabetes Control and Complications Trial. Randomized Controlled Trial","volume":"75","year":"1995","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.pop.2005.09.001_bib86","doi-asserted-by":"crossref","first-page":"2560","DOI":"10.1001\/jama.289.19.2560","article-title":"The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report","volume":"289","author":"Chobanian","year":"2003","journal-title":"JAMA"},{"key":"10.1016\/j.pop.2005.09.001_bib87","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1056\/NEJM199511163332001","article-title":"Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia","volume":"333","author":"Shepherd","year":"1995","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pop.2005.09.001_bib88","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1056\/NEJM199811053391902","article-title":"Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels","volume":"339","author":"Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group","year":"1998","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pop.2005.09.001_bib89","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1016\/j.jacc.2004.07.001","article-title":"Implications of recent clinical trials for the national cholesterol education program adult treatment panel III guidelines","volume":"44","author":"Grundy","year":"2004","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.pop.2005.09.001_bib90","series-title":"Cardiac rehabilitation as secondary prevention. Clinical practice guideline no. 17","author":"Wenger","year":"1995"},{"key":"10.1016\/j.pop.2005.09.001_bib91","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/S0025-7125(05)70217-0","article-title":"Effects of exercise and cardiac rehabilitation on cardiovascular outcomes","volume":"84","author":"Ades","year":"2000","journal-title":"Med Clin North Am"},{"key":"10.1016\/j.pop.2005.09.001_bib92","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1056\/NEJMoa043399","article-title":"Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT) Investigators. Amiodarone or an implantable cardioverter-defibrillator for congestive heart failure","volume":"352","author":"Bardy","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pop.2005.09.001_bib93","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1056\/NEJMoa013474","article-title":"Prophylactic implantation of a defibrillator in patients with myocardial infarction and reduced ejection fraction","volume":"346","author":"Moss","year":"2002","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pop.2005.09.001_bib94","doi-asserted-by":"crossref","first-page":"1882","DOI":"10.1056\/NEJM199912163412503","article-title":"Multicenter Unsustained Tachycardia Trial Investigators. A randomized study of the prevention of sudden death in patients with coronary artery disease","volume":"341","author":"Buxton","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pop.2005.09.001_bib95","doi-asserted-by":"crossref","first-page":"2481","DOI":"10.1056\/NEJMoa041489","article-title":"Prophylactic use of an implantable cardioverter-defibrillator after acute myocardial infarction","volume":"351","author":"Hohnloser","year":"2004","journal-title":"N Engl J Med"}],"container-title":["Primary Care: Clinics in Office Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S009545430500076X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S009545430500076X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,4,19]],"date-time":"2020-04-19T17:42:36Z","timestamp":1587318156000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S009545430500076X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,12]]},"references-count":95,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2005,12]]}},"alternative-id":["S009545430500076X"],"URL":"https:\/\/doi.org\/10.1016\/j.pop.2005.09.001","relation":{},"ISSN":["0095-4543"],"issn-type":[{"value":"0095-4543","type":"print"}],"subject":[],"published":{"date-parts":[[2005,12]]}}}