{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T03:49:12Z","timestamp":1648525752461},"reference-count":49,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2006,12,1]],"date-time":"2006-12-01T00:00:00Z","timestamp":1164931200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Primary Care: Clinics in Office Practice"],"published-print":{"date-parts":[[2006,12]]},"DOI":"10.1016\/j.pop.2006.09.007","type":"journal-article","created":{"date-parts":[[2007,1,10]],"date-time":"2007-01-10T14:28:46Z","timestamp":1168439326000},"page":"903-921","source":"Crossref","is-referenced-by-count":0,"title":["Common Questions in Managing Hyperlipidemia"],"prefix":"10.1016","volume":"33","author":[{"given":"Irene M.","family":"Rosen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"II","given":"Richard W.","family":"Sams","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.pop.2006.09.007_bib1","unstructured":"Number of office visits (in thousands) by patients age 45 to 64 to selected specialties ranked by the 20 most frequent principal diagnoses by the physician (ICD-9 three digit code in parentheses), 2002. Available at: http:\/\/www.aafp.org\/x25058.xml. Accessed on December 28, 2005."},{"key":"10.1016\/j.pop.2006.09.007_bib2","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1161\/01.CIR.0000133317.49796.0E","article-title":"Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines","volume":"110","author":"Grundy","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.pop.2006.09.007_bib3","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.1056\/NEJMe058052","article-title":"Low-density lipoprotein cholesterol in patients with stable coronary artery disease\u2014is it time to shift our goals?","volume":"352","author":"Pitt","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pop.2006.09.007_bib4","first-page":"549","article-title":"Strength of Recommendation Taxonomy (SORT): A patient-centered approach to grading evidence in the medical literature","volume":"69","author":"Ebell","year":"2004","journal-title":"Am Fam Physician"},{"key":"10.1016\/j.pop.2006.09.007_bib5","doi-asserted-by":"crossref","first-page":"3143","DOI":"10.1161\/circ.106.25.3143","article-title":"Third report of the National Cholesterol Education Program (NCEP) Expert Panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III)","volume":"106","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.pop.2006.09.007_bib6","unstructured":"National Heart, Lung and Blood Institute. http:\/\/www.nhlbi.nih.gov\/guidelines\/cholesterol. Accessed December 2005."},{"key":"10.1016\/j.pop.2006.09.007_bib7","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1001\/jama.286.2.180","article-title":"Validation of the Framingham Coronary Heart Disease Prediction Scores: results of a multiple ethnic groups investigation","volume":"286","author":"D'Agostino","year":"2001","journal-title":"JAMA"},{"key":"10.1016\/j.pop.2006.09.007_bib8","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1001\/archinte.165.7.725","article-title":"Effects of different antilipidemic agents and diets on mortality","volume":"165","author":"Studer","year":"2005","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.pop.2006.09.007_bib9","doi-asserted-by":"crossref","first-page":"2511","DOI":"10.1097\/00007611-199310001-00003","article-title":"Cholesterol and the older adult","volume":"86","author":"Kaiser","year":"1993","journal-title":"South Med J"},{"key":"10.1016\/j.pop.2006.09.007_bib10","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S0140-6736(02)09327-3","article-title":"MRC\/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomized placebo-controlled trial","volume":"360","author":"Vaughan","year":"2002","journal-title":"Lancet"},{"key":"10.1016\/j.pop.2006.09.007_bib11","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1056\/NEJMoa050461","article-title":"Intensive lipid lowering with atorvastatin in patients with stable coronary artery disease","volume":"352","author":"LaRosa","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pop.2006.09.007_bib12","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1016\/S0140-6736(03)12948-0","volume":"361","author":"Sever","year":"2003","journal-title":"Lancet"},{"key":"10.1016\/j.pop.2006.09.007_bib13","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1056\/NEJMoa040583","article-title":"Pravastatin or Atorvastatin Evaluation and Infection Therapy\u2013Thrombolysis in Myocardial Infarction 22 Investigators. Intensive versus moderate lipid lowering with statins after acute coronary syndromes","volume":"350","author":"Cannon","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pop.2006.09.007_bib14","doi-asserted-by":"crossref","first-page":"7B","DOI":"10.1016\/S0002-9149(98)00031-9","article-title":"Hypertriglyceridemia as a cardiovascular risk factor","volume":"81","author":"Austin","year":"1998","journal-title":"Am J Cardiol"},{"issue":"Suppl M","key":"10.1016\/j.pop.2006.09.007_bib15","first-page":"M8","article-title":"The emergence of triglycerides as a significant independent risk factor in coronary artery disease","volume":"19","author":"Assmann","year":"1998","journal-title":"Eur Heart J"},{"key":"10.1016\/j.pop.2006.09.007_bib16","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1161\/01.CIR.100.5.475","article-title":"Elevated serum triglyceride levels and long-term mortality in patients with coronary heart disease","volume":"100","author":"Haim","year":"1999","journal-title":"Circulation"},{"key":"10.1016\/j.pop.2006.09.007_bib17","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1056\/NEJM199908053410604","article-title":"Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high density lipoprotein cholesterol","volume":"341","author":"Rubins","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pop.2006.09.007_bib18","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1001\/jama.1975.03240160024021","article-title":"Clofibrate and niacin in coronary heart disease","volume":"231","author":"The Coronary Drug Project Research Group","year":"1975","journal-title":"JAMA"},{"key":"10.1016\/j.pop.2006.09.007_bib19","unstructured":"Boehringer SK. Niacin use: an update. Pharmacist's Letter\/Prescriber's Letter 2005;21(12):211207."},{"key":"10.1016\/j.pop.2006.09.007_bib20","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1016\/S0140-6736(05)67394-1","article-title":"Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins","volume":"366","author":"Baigent","year":"2005","journal-title":"Lancet"},{"key":"10.1016\/j.pop.2006.09.007_bib21","doi-asserted-by":"crossref","first-page":"1793","DOI":"10.1001\/archinte.159.15.1793","article-title":"Clinical outcomes in statin treatment trials. A meta-analysis","volume":"159","author":"Ross","year":"1999","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.pop.2006.09.007_bib22","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.1001\/jama.279.20.1615","article-title":"Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels. Results of AFCAPS\/TexCAPS","volume":"279","author":"Downs","year":"1998","journal-title":"JAMA"},{"key":"10.1016\/j.pop.2006.09.007_bib23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1136\/bmj.321.7267.983","article-title":"Use of lipid lowering drugs for primary prevention of coronary heart disease: a meta-analysis of randomised trials","volume":"321","author":"Pignone","year":"2000","journal-title":"BMJ"},{"key":"10.1016\/j.pop.2006.09.007_bib24","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1016\/j.amjmed.2004.04.022","article-title":"Effects of statins on stroke prevention in patients with and without coronary heart disease: a meta-analysis of randomized controlled trials","volume":"117","author":"Briel","year":"2004","journal-title":"Am J Med"},{"issue":"3","key":"10.1016\/j.pop.2006.09.007_bib25","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD002091","article-title":"Interventions in the management of serum lipids for preventing stroke recurrence","author":"Manktelow","year":"2002","journal-title":"Cochrane Databases Syst Rev"},{"key":"10.1016\/j.pop.2006.09.007_bib26","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1056\/NEJM200008033430502","article-title":"Pravastatin therapy and the risk of stroke","volume":"343","author":"White","year":"2000","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pop.2006.09.007_bib27","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/S0140-6736(04)15690-0","article-title":"Effects of cholesterol-lowering with simvastatin on stroke and other major vascular events in 20,536 people with cerebrovascular disease or other high-risk conditions","volume":"363","author":"Collins","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.pop.2006.09.007_bib28","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/S0002-9343(03)00303-6","article-title":"Evaluating the benefits of treating dyslipidemia: the importance of diabetes as a risk factor","volume":"115","author":"Grover","year":"2003","journal-title":"Am J Med"},{"key":"10.1016\/j.pop.2006.09.007_bib29","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/S0002-9343(01)00978-0","article-title":"The effects of interventions to prevent cardiovascular disease in patients with type 2 diabetes mellitus","volume":"111","author":"Huang","year":"2001","journal-title":"Am J Med"},{"key":"10.1016\/j.pop.2006.09.007_bib30","doi-asserted-by":"crossref","first-page":"1850","DOI":"10.1001\/jama.285.14.1850","article-title":"Use of statins and risk of fractures","volume":"285","author":"Van Staa","year":"2001","journal-title":"JAMA"},{"key":"10.1016\/j.pop.2006.09.007_bib31","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1056\/NEJMoa011090","article-title":"Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease","volume":"345","author":"Brown","year":"2001","journal-title":"N Engl J Med"},{"issue":"10B","key":"10.1016\/j.pop.2006.09.007_bib32","doi-asserted-by":"crossref","first-page":"21K","DOI":"10.1016\/S0002-9149(02)02968-5","article-title":"Combination therapy for combined dyslipidemia","volume":"90","author":"Xydakis","year":"2002","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.pop.2006.09.007_bib33","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/S0025-7125(16)30184-5","article-title":"Drug treatment of dyslipoproteinemia","volume":"78","author":"Larsen","year":"1994","journal-title":"Med Clin North Am"},{"key":"10.1016\/j.pop.2006.09.007_bib34","unstructured":"Kehoe, WA. Combination cholesterol-lowering therapy. Pharmacist's Letter\/Prescriber's Letter 2003;19:190304."},{"key":"10.1016\/j.pop.2006.09.007_bib35","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1345\/aph.10315","article-title":"Statin-fibrate combination therapy","volume":"35","author":"Shek","year":"2001","journal-title":"Ann Pharmacother"},{"key":"10.1016\/j.pop.2006.09.007_bib36","doi-asserted-by":"crossref","first-page":"2409","DOI":"10.1161\/01.CIR.0000068312.21969.C8","article-title":"Effect of ezetimibe coadministered with atorvastatin in 628 patients with primary hypercholesterolemia","volume":"107","author":"Ballantyne","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.pop.2006.09.007_bib37","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/S0735-1097(02)02030-2","article-title":"ACC\/AHA\/NHLBI clinical advisory on the use and safety of statins","volume":"40","author":"Pasternak","year":"2002","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.pop.2006.09.007_bib38","doi-asserted-by":"crossref","first-page":"3051","DOI":"10.1161\/CIRCULATIONAHA.105.555482","article-title":"The safety of rosuvastatin as used in common clinical practice: a postmarketing analysis","volume":"111","author":"Alsheikh-Ali","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.pop.2006.09.007_bib39","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1136\/bmj.322.7277.11","article-title":"Cholesterol reduction and non-illness mortality: meta-analysis of randomised clinical trials","volume":"322","author":"Muldoon","year":"2001","journal-title":"BMJ"},{"key":"10.1016\/j.pop.2006.09.007_bib40","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1111\/j.1532-5415.2005.53106.x","article-title":"Relationship between plasma lipids and all-cause mortality in nondemented elderly","volume":"53","author":"Schupf","year":"2005","journal-title":"J Am Geriatr Soc"},{"key":"10.1016\/j.pop.2006.09.007_bib41","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1046\/j.1525-1497.2000.03509.x","article-title":"Blood cholesterol screening","volume":"15","author":"Craig","year":"2000","journal-title":"J Gen Intern Med"},{"key":"10.1016\/j.pop.2006.09.007_bib42","doi-asserted-by":"crossref","first-page":"1959","DOI":"10.1056\/NEJM200106283442601","article-title":"Measurement of c-reactive protein for the targeting of statin therapy in the primary prevention of acute coronary events","volume":"344","author":"Ridker","year":"2001","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pop.2006.09.007_bib43","doi-asserted-by":"crossref","first-page":"2677","DOI":"10.1161\/01.CIR.102.22.2677","article-title":"Fish oil-derived fatty acids, docosahexaenoic acid and docosapentaenoic acid, and the risk of acute coronary events: the Kuopio ischaemic heart disease risk factor study","volume":"102","author":"Rissanen","year":"2000","journal-title":"Circulation"},{"key":"10.1016\/j.pop.2006.09.007_bib44","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/S0002-9343(01)01114-7","article-title":"N-3 polyunsaturated fatty acids in coronary heart disease: a meta-analysis of randomized controlled trials","volume":"112","author":"Bucher","year":"2002","journal-title":"Am J Med"},{"key":"10.1016\/j.pop.2006.09.007_bib45","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1161\/01.CIR.99.6.779","article-title":"Mediterranean diet, traditional risk factors, and the rate of cardiovascular complications after myocardial infarction","volume":"99","author":"De Lorgeril","year":"1999","journal-title":"Circulation"},{"key":"10.1016\/j.pop.2006.09.007_bib46","doi-asserted-by":"crossref","first-page":"420","DOI":"10.7326\/0003-4819-133-6-200009190-00009","article-title":"Garlic for treating hypercholesterolemia. A meta-analysis of randomized clinical trial","volume":"133","author":"Stevinson","year":"2000","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.pop.2006.09.007_bib47","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1056\/NEJM199508033330502","article-title":"Meta-analysis of the effects of soy protein intake on serum lipids","volume":"333","author":"Anderson","year":"1995","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pop.2006.09.007_bib48","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1093\/ajcn\/69.1.30","article-title":"Cholesterol-lowering effects of dietary fiber: a meta-analysis","volume":"69","author":"Brown","year":"1999","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.pop.2006.09.007_bib49","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.1001\/archinte.163.12.1448","article-title":"Cholesterol-lowering effect of a theaflavin-enriched green tree extract: a randomized controlled trial","volume":"163","author":"Maron","year":"2003","journal-title":"Arch Intern Med"}],"container-title":["Primary Care: Clinics in Office Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0095454306000753?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0095454306000753?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,23]],"date-time":"2019-04-23T16:56:20Z","timestamp":1556038580000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0095454306000753"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,12]]},"references-count":49,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2006,12]]}},"alternative-id":["S0095454306000753"],"URL":"https:\/\/doi.org\/10.1016\/j.pop.2006.09.007","relation":{},"ISSN":["0095-4543"],"issn-type":[{"value":"0095-4543","type":"print"}],"subject":[],"published":{"date-parts":[[2006,12]]}}}