{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T20:47:08Z","timestamp":1762980428543},"reference-count":39,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Progress in Pediatric Cardiology"],"published-print":{"date-parts":[[2017,9]]},"DOI":"10.1016\/j.ppedcard.2017.06.007","type":"journal-article","created":{"date-parts":[[2017,7,10]],"date-time":"2017-07-10T15:45:55Z","timestamp":1499701555000},"page":"23-27","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Noncompaction cardiomyopathy and heterotaxy syndrome"],"prefix":"10.1016","volume":"46","author":[{"given":"Hugo R.","family":"Martinez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephanie M.","family":"Ware","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcus S.","family":"Schamberger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John J.","family":"Parent","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ppedcard.2017.06.007_bb0005","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1161\/CIRCULATIONAHA.106.174287","volume":"113","author":"Maron","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0010","doi-asserted-by":"crossref","DOI":"10.1038\/nrcardio.2016.207","article-title":"Left ventricular noncompaction cardiomyopathy: cardiac, neuromuscular, and genetic factors","author":"Finsterer","year":"2017","journal-title":"Nat Rev Cardiol"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0015","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.ijcard.2015.03.065","article-title":"Reference values for left and right ventricular trabeculation and non-compacted myocardium","volume":"185","author":"Andre","year":"2015","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0020","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1016\/j.amjcard.2014.07.025","article-title":"Characteristics of trabeculated myocardium burden in young and apparently healthy adults","volume":"114","author":"Tizon-Marcos","year":"2014","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0025","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/j.jacc.2015.06.017","article-title":"Isolated noncompaction of the left ventricle in adults","volume":"66","author":"Hussein","year":"2015","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0030","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1002\/ajmg.c.31369","article-title":"Molecular mechanism of ventricular trabeculation\/compaction and the pathogenesis of the left ventricular noncompaction cardiomyopathy (LVNC)","volume":"163C","author":"Zhang","year":"2013","journal-title":"Am J Med Genet C: Semin Med Genet"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0035","doi-asserted-by":"crossref","first-page":"2477","DOI":"10.1016\/j.ijcard.2012.05.095","article-title":"Left ventricular non-compaction: prevalence in congenital heart disease","volume":"167","author":"Stahli","year":"2013","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0040","doi-asserted-by":"crossref","first-page":"1446","DOI":"10.1093\/eurheartj\/ehq508","article-title":"Left ventricular non-compaction revisited: a distinct phenotype with genetic heterogeneity?","volume":"32","author":"Oechslin","year":"2011","journal-title":"Eur Heart J"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0045","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.jacc.2005.03.045","article-title":"Left ventricular non-compaction: insights from cardiovascular magnetic resonance imaging","volume":"46","author":"Petersen","year":"2005","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0050","first-page":"301","article-title":"Non-compaction cardiomyopathy-echocardiographic diagnosis","volume":"3","author":"Bax","year":"2002","journal-title":"Eur J Echocardiogr"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0055","doi-asserted-by":"crossref","first-page":"2166","DOI":"10.1016\/j.jacc.2016.08.053","article-title":"Long-term prognostic value of cardiac magnetic resonance in left ventricle noncompaction: a prospective multicenter study","volume":"68","author":"Andreini","year":"2016","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0060","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1016\/j.jacc.2016.05.096","article-title":"Left ventricular noncompaction: a distinct genetic cardiomyopathy?","volume":"68","author":"Arbustini","year":"2016","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0065","doi-asserted-by":"crossref","first-page":"2672","DOI":"10.1161\/01.CIR.0000100664.10777.B8","article-title":"Clinical characterization of left ventricular noncompaction in children: a relatively common form of cardiomyopathy","volume":"108","author":"Pignatelli","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0070","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1016\/j.cardfail.2006.08.002","article-title":"Clinical features of isolated ventricular noncompaction in adults long-term clinical course, echocardiographic properties, and predictors of left ventricular failure","volume":"12","author":"Aras","year":"2006","journal-title":"J Card Fail"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0075","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1016\/j.amjcard.2009.05.062","article-title":"Isolated left ventricular noncompaction syndrome","volume":"104","author":"Stanton","year":"2009","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0080","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.4330\/wjc.v6.i11.1156","article-title":"Importance of genetic evaluation and testing in pediatric cardiomyopathy","volume":"6","author":"Tariq","year":"2014","journal-title":"World J Cardiol"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0085","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1093\/cvr\/cvu193","article-title":"Scrib: Rac1 interactions are required for the morphogenesis of the ventricular myocardium","volume":"104","author":"Boczonadi","year":"2014","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0090","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1086\/380998","article-title":"Identification and functional analysis of ZIC3 mutations in heterotaxy and related congenital heart defects","volume":"74","author":"Ware","year":"2004","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0095","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1161\/CIRCGENETICS.115.001026","article-title":"Loss of function mutations in NNT are associated with left ventricular noncompaction","volume":"8","author":"Bainbridge","year":"2015","journal-title":"Circ Cardiovasc Genet"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0100","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1177\/2150135110397670","article-title":"Heterotaxy: lessons learned about patterns of practice and outcomes from the congenital heart surgery database of the society of thoracic surgeons","volume":"2","author":"Jacobs","year":"2011","journal-title":"World J Pediatr Congenit Heart Surg"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0105","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1007\/s00246-016-1435-2","article-title":"The impact of concomitant left ventricular non-compaction with congenital heart disease on perioperative outcomes","volume":"37","author":"Ramachandran","year":"2016","journal-title":"Pediatr Cardiol"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0110","doi-asserted-by":"crossref","DOI":"10.1136\/openhrt-2015-000328","article-title":"Predictors of poor outcome among children with heterotaxy syndrome: a retrospective review","volume":"3","author":"McGovern","year":"2016","journal-title":"Open Heart"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0115","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1017\/S1047951105001708","article-title":"Hearts with isomerism of the right atrial appendages - one of the worst forms of disease in 2005","volume":"15","author":"Freedom","year":"2005","journal-title":"Cardiol Young"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0120","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1097\/00125817-200005000-00002","article-title":"Heterotaxy: associated conditions and hospital-based prevalence in newborns","volume":"2","author":"Lin","year":"2000","journal-title":"Genet Med"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0125","doi-asserted-by":"crossref","first-page":"1909","DOI":"10.1161\/01.CIR.94.8.1909","article-title":"Failure to detect connexin43 mutations in 38 cases of sporadic and familial heterotaxy","volume":"94","author":"Gebbia","year":"1996","journal-title":"Circulation"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0130","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1097\/00001573-200405000-00005","article-title":"Molecular genetics of heterotaxy syndromes","volume":"19","author":"Belmont","year":"2004","journal-title":"Curr Opin Cardiol"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0135","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1002\/humu.22457","article-title":"Genetic and functional analyses of ZIC3 variants in congenital heart disease","volume":"35","author":"Cowan","year":"2014","journal-title":"Hum Mutat"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0140","doi-asserted-by":"crossref","DOI":"10.1098\/rstb.2015.0406","article-title":"Copy number variation as a genetic basis for heterotaxy and heterotaxy-spectrum congenital heart defects","volume":"371","author":"Cowan","year":"2016","journal-title":"Philos Trans R Soc Lond Ser B Biol Sci"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0145","doi-asserted-by":"crossref","first-page":"2814","DOI":"10.1161\/CIRCULATIONAHA.106.649038","article-title":"Congenital heart disease and other heterotaxic defects in a large cohort of patients with primary ciliary dyskinesia","volume":"115","author":"Kennedy","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0150","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1378\/chest.13-1704","article-title":"Laterality defects other than situs inversus totalis in primary ciliary dyskinesia: insights into situs ambiguus and heterotaxy","volume":"146","author":"Shapiro","year":"2014","journal-title":"Chest"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0155","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1161\/CIRCRESAHA.106.142406","article-title":"Disruption of planar cell polarity signaling results in congenital heart defects and cardiomyopathy attributable to early cardiomyocyte disorganization","volume":"101","author":"Phillips","year":"2007","journal-title":"Circ Res"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0160","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1002\/dvdy.20719","article-title":"Heart defects in X-linked heterotaxy: evidence for a genetic interaction of Zic3 with the nodal signaling pathway","volume":"235","author":"Ware","year":"2006","journal-title":"Dev Dyn"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0165","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1002\/ajmg.c.30228","article-title":"Disorders of left-right asymmetry: heterotaxy and situs inversus","volume":"151C","author":"Sutherland","year":"2009","journal-title":"Am J Med Genet C: Semin Med Genet"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0170","doi-asserted-by":"crossref","first-page":"e33","DOI":"10.5935\/abc.20130158","article-title":"Dextrocardia with situs inversus associated with non-compaction cardiomyopathy","volume":"101","author":"Goncalves","year":"2013","journal-title":"Arq Bras Cardiol"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0175","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1136\/heart.86.6.666","article-title":"Echocardiographic and pathoanatomical characteristics of isolated left ventricular non-compaction: a step towards classification as a distinct cardiomyopathy","volume":"86","author":"Jenni","year":"2001","journal-title":"Heart"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0180","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.1016\/S0003-4975(01)03039-9","article-title":"Improving outcomes of the Fontan operation in children with atrial isomerism and heterotaxy syndromes","volume":"72","author":"Azakie","year":"2001","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0185","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.jtcvs.2008.10.027","article-title":"Biventricular repair in patients with heterotaxy syndrome","volume":"137","author":"Lim","year":"2009","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0190","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1006\/geno.2001.6638","article-title":"Circletail, a new mouse mutant with severe neural tube defects: chromosomal localization and interaction with the loop-tail mutation","volume":"78","author":"Murdoch","year":"2001","journal-title":"Genomics"},{"key":"10.1016\/j.ppedcard.2017.06.007_bb0195","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1038\/nature01618","article-title":"Identification of Vangl2 and Scrb1 as planar polarity genes in mammals","volume":"423","author":"Montcouquiol","year":"2003","journal-title":"Nature"}],"container-title":["Progress in Pediatric Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1058981317300942?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1058981317300942?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,2,10]],"date-time":"2019-02-10T11:34:25Z","timestamp":1549798465000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1058981317300942"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9]]},"references-count":39,"alternative-id":["S1058981317300942"],"URL":"https:\/\/doi.org\/10.1016\/j.ppedcard.2017.06.007","relation":{},"ISSN":["1058-9813"],"issn-type":[{"value":"1058-9813","type":"print"}],"subject":[],"published":{"date-parts":[[2017,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Noncompaction cardiomyopathy and heterotaxy syndrome","name":"articletitle","label":"Article Title"},{"value":"Progress in Pediatric Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ppedcard.2017.06.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}